PUFA SALT FORMULATIONS (II)

Abstract

The present patent application relates to novel polyunsaturated fatty acid salt (PUFA salts) solid formulations.

Claims

1. A solid formulation comprising (i) at least one PUFA salt, and (ii) at least one protein hydrolysate from a starch containing plant.

2. Solid formulation according to claim 1, wherein the average particle size (Dv50) of the solid formulation is 10-200 m.

3. Solid formulation according to claim 1, wherein the average particle size (Dv50) of the solid formulation is 200-1000 m.

4. Solid formulation according to claim 1, wherein the average particle size (Dv50) of the solid formulation is more than 1000 m.

5. Solid formulation according to claim 1, wherein the PUFA salts are the sodium, potassium, magnesium and/or calcium salts.

6. Solid formulation according to claim 1, wherein the PUFA salts are chosen from the group consisting of linoleic acid, arachidonic acid, -linolenic acid, dihomo--linolenic acid, -linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid in form of its sodium, potassium and/or calcium salts.

7. Solid formulation according to claim 1, wherein the solid formulation comprises 5-80 wt-%, based on the total weight of the solid formulation, of at least one PUFA salt.

8. Solid formulation according to claim 1, wherein the solid formulation comprising 10-75 wt-%, based on the total weight of the solid formulation, of at least one protein hydrolysate from a starch containing plant.

9. Solid formulation according to claim 1, wherein the solid formulation comprises up to 30 wt-%, based on the total weight of the solid formulation, of at least one gum.

10. Solid formulation according to claim 1, wherein the solid formulation comprises up to 30 wt-%, based on the total weight of the solid formulation, of at least one sugar alcohol.

11. Solid formulation according to claim 1, wherein the solid formulation comprises at least one auxiliary agent, wherein the auxiliary agent is chosen from the group consisting of antioxidants chosen from the groups consisting of ascorbic acid or salts thereof, synthetic tocopherol, natural tocopherol, butylated hydroxytoluene, butylated hydroxyanisole, propyl gallate; tert. butyl hydroxyquinoline, ascorbic acid esters of a fatty acid and ethoxyquin; plasticisers, stabilisers; humectants chosen from the group consisting of glycerine, sorbitol and polyethylene glycol; protective colloids; dyes; fragrances; fillers and buffers.

12. Process of production of the solid formulation wherein (i) the water soluble ingredients of the matrix are mixed in their dry form and then dissolved in water; afterwards (ii) the PUFA salt is added, afterwards (iii) the mixture is spray dried.

13. Food products, feed products, dietary supplements, pharmaceutical products and/or premixes, comprising at least one solid formulation according to claim 1.

14. Use of at least one protein hydrolysate from a starch containing plant for manufacturing a solid formulation comprising at least one PUFA salt.

Description

EXAMPLE 1

[0102] 25 g of maltodextrin (maltodextrin 28-31), 20 g of sodium ascorbate and 80 g of rice hydrolysate (Hyvital Rice CMA 500 from FrieslandCampina Domo) were put (in their dry state) into a beaker and mixed well.

[0103] Afterward 800 g of water were added slowly to this mixture under constant stirring. This solution was heated up to 50 C., and adjust the pH was adjusted (by NaOH or KOH) to 8.5.

[0104] The PUFA salt (the Na salt of MEG-3 4030 EE Oil) was also heated up to 50 C. and then the warm PUFA salt was added to the aqueous solution. A slurry way obtained.

[0105] The so obtained slurry was spray dried (using a GEA MOBILE MINOR), inlet temperature was set at 150180 C., outlet temperature was controlled around 6080 C. A free-flowing powder was obtained.

[0106] Testing of the Solid Formulations

[0107] The storage stability of the produced solid formulations was tested as follows:

[0108] The solid formulations were stored at room temperature and after defined storage times the formulations were evaluated by a sensory panel of experienced and well-trained persons.

[0109] Each person of this panel sniffed at the solid formulations and gave them a value of the sensory scale.

[0110] This sensory scale, which was applied, has values that goes from 0 to 15.0 means no smell 15 means extremely strong.

[0111] The following compositions are tested (the amount of the ingredients is given in gram (g)):

TABLE-US-00001 TABLE 1 Formulations (1-2). The formulation 1 is the one produced as in Example 1. The form 2 is produced according to the method of example 1. Ingredients FORM 1 FORM2 PUFA Na Salt of MEG- 250 250 3 4030 EE Oil Maltodextrin 28-31 25 25 Sodium Ascorbate 15 20 Rice hydrolysate 80 130 Water 1000 1000

TABLE-US-00002 TABLE 2 the sensory results of the forms 1-2 Fishy Marine Complex Other Off FORM 1 initial 0.8 4 weeks 1.0 0.5 8 weeks 1.0 12 weeks 1.0 16 weeks 0.8 20 weeks 0.8 FORM 2 initial 4 weeks 4.0 8 weeks 2.5 12 weeks 3.0 16 weeks 3.5 20 weeks 1.5

[0112] Formulations 3 and 4:

[0113] The formulations are produced in accordance with the process as disclosed in Example 1.

TABLE-US-00003 TABLE 3 formulations 3 and 4 Ingredients FORM 3 FORM 4 PUFA Na Salt 40:30 250 250 Maltodextrin 28-31 25 65 Sodium Ascorbate 20 20 Rice hydrolysate 60 60 TIC Pretested Gum Arabic 70 Spray Dry Powder - Grade #1 Alginate LFR 5/60 30 Water 1000 1000

[0114] Sensory Results

TABLE-US-00004 TABLE 4 sensory results of formulations 3 and 4 Fishy Marine Complex Other Off FORM 3 initial 4 weeks 8 weeks 12 weeks 0.8 16 weeks 20 weeks FORM 4 initial 1.0 4 weeks 2.0 8 weeks 12 weeks 0.8 16 weeks 20 weeks

[0115] Formulations 5 and 6:

TABLE-US-00005 TABLE 5 formulations 5 and 6 (these are comparative examples) Ingredient FORM 5-9 FORM 6 PUFA Na Salt 40:30 250 250 Maltodextrin 28-31 25 25 Sodium Ascorbate 15 15 Supro 313 80 Soy isolate Partially hydro Supro 670 80 Soy isolate Partially hydro

[0116] Sensory Results

TABLE-US-00006 TABLE 6 sensory results of formulations 5 and 6 Fishy Marine Complex Other Off FORM 5 initial 3 4 weeks 5 8 weeks 4 FORM 6 initial 4 4 weeks 4 8 weeks 5

[0117] Formulation 7:

TABLE-US-00007 TABLE 7 formulation 7 (comparative example) Ingredient FORM 7 PUFA Na Salt 40:30 250 Maltodextrin 28-31 25 Sodium Ascorbate 15 Cottonseed hydrolysate 80 Water 1000

[0118] Sensory Results

TABLE-US-00008 TABLE 6 sensory results of formulation 7 Fishy Marine Complex Other Off FORM 7 initial 0 4 weeks 4

[0119] It can be seen from these evaluation tests that the solid formulations according to the present invention are better significantly than such, which are produced with a different (commonly and widely used) matrix material.