SPRAY DEPOSITION SYSTEM AND ITS USE FOR TREATING A LIVING BEING

Abstract

The present invention provides a spray deposition system which comprises a syringe attachment device having a specific adaptor. The adaptor has at least three openings being in fluid connection with each other, wherein at least one first opening of the adaptor is connectable to a needle in a liquid-tight manner, at least one second opening of the adaptor is in fluid connection with surrounding air and at least one third opening of the adaptor is connected to a tube configured to deliver an air flow in a reversible and air-tight manner. Thereby, a connection to a needle is possible in a reversible and liquid-tight manner without having to pierce the tube of the system like in prior art solutions. This provokes that no tube material may clog the needle and no air may leak from the tube. Furthermore, an attachment of the needle to the spray deposition system may be performed faster and safer and alignment of the needle is facilitated. Finally, dulled needles may be employed which ensure a more homogeneous deposition of liquid from the needle.

Claims

1. A spray deposition system, comprising: a) a syringe attachment device having a base with a coupling portion and a top portion, the syringe attachment device comprising: i) a syringe channel configured to receive at least parts of a syringe; and ii) a tube configured to deliver an air flow; b) a handheld device having an upper surface and including a movable slide disposed on the upper surface, wherein the handheld device is configured to be coupled to the coupling portion of the syringe attachment device in an assembled position of the system and wherein the handheld device is configured to control delivery of a treatment solution from the syringe; wherein the syringe attachment device comprises an adaptor having at least three openings in fluid connection with each other, wherein at least one first opening of the adaptor is connectable to a needle in a liquid-tight manner, at least one second opening of the adaptor is in fluid connection with surrounding air and at least one third opening of the adaptor is connected to the tube in a reversible and air-tight manner.

2. The spray deposition system according to claim 1, wherein the at least one first and the at least one second opening of the adaptor are fluidly connected by a first fluid channel, wherein the first fluid channel has i) an approximately straight form; ii) a length configured to accommodate the needle, wherein a tip of the needle becomes located approximately at the same pitch as the at least one third opening; iii) a length of 20 to 40 mm; iv) a first section for liquid-tightly connecting a needle adaptor configured for connecting the needle to the syringe, wherein the first section extends from the at least one first opening of the adaptor towards the at least one second opening of the adaptor, wherein the first section has a diameter of 0.5 to 8 mm and a length of 10 to 20 mm; v) a second section for accommodating the needle, wherein the second section is located away from the at least one first opening of the adaptor, wherein the second section has a diameter of 0.2 to 3 mm and a length of 5 to 15 mm; vi) a third section for spray deposition of contents of the syringe, wherein the third section is located at the at least one second opening, wherein the third section has a conical form, with a diameter of at least 2 mm and a length of 0.5 to 4 mm; and vii) the needle located therein, the needle having a dulled tip.

3. The spray deposition system according to claim 1, wherein the at least one third opening is fluidly connected to the at least one first opening and the at least one second opening of the adaptor by a second fluid channel_, wherein the second fluid channel has i) an essentially straight form; ii) a length of 4 to 40 mm; and iii) a section for accommodating the tube configured to deliver an air flow, wherein the section is located at the at least one third opening, wherein the section has a diameter of 1 to 5 mm, and a shorter length than the second fluid channel.

4. The spray deposition system according to claim 1, wherein the at least one first and the at least one second opening of the adaptor are fluidly connected by a first fluid channel and the at least one third opening of the adaptor is fluidly connected to the at least one first opening and the at least one second opening by a second fluid channel, wherein i) the second fluid channel fluidly connects substantially perpendicular to the first fluid channel, wherein the connection point has the form of a T-shape; and ii) the second fluid channel fluidly connects to the first fluid channel at a section of the first fluid channel at which a part of the needle becomes located which is closer an adaptor of the needle than to a tip of the needle.

5. The spray deposition system according to claim 1, wherein the first opening of the adaptor is configured for reversibly and liquid-tightly connecting to a Luer-lock connector.

6. The spray deposition system according to claim 1, wherein the at least one first opening of the adaptor is connected to the needle.

7. The spray deposition system according to claim 1, wherein the adaptor i) is sterile; and ii) comprises a plastic including polyurethane, polycarbonate, polyvinylchloride, acrylonitrile-butadiene-styrene, or polyurethane SG 95.

8. The spray deposition system according to claim 1, wherein the syringe attachment device comprises i) a bottom surface of the coupling portion, the bottom surface configured to couple with a top portion of the handheld device in the assembled portion; ii) at least one feature on the coupling portion to engage a corresponding feature on an upper surface of the handheld device; iii) an air filter coupled to the tube; iv) an airflow indicator coupled to the tube; and v) the needle having a taper fitting.

9. The spray deposition system according to claim 1, wherein the handheld device comprises i) a movable slide including a plunger driver configured to engage a plunger of a syringe disposed in the syringe channel, wherein the plunger is configured to be electronically positionable or manually positionable; ii) the movable slide being controlled by a threaded shaft, wherein a coupler is configured for engagement with the movable slide and the threaded shaft, and movement of the coupler on the threaded shaft corresponds to movement of the slide on the handheld device; iii) a switch configured to electronically control the movable slide; iv) a battery compartment, wherein an electrical contact of the battery compartment is electrically coupled to the movable slide; v) spray volume indicia; and vi) a first mark and a sterile cover includes a second mark, and wherein the first and second marks are configured for alignment to determine placement of the sterile cover around at least a portion of the handheld device.

10. The spray deposition system according to claim 1, wherein the handheld device i) is inserted into a sterile cover and the sterile cover encloses the handheld device in the assembled position; and ii) is reusable and the syringe attachment device is disposable.

11. The spray deposition system according to claim 1, wherein the spray deposition system further comprises a sterile cover, wherein the sterile cover is i) coupled to the syringe attachment device between a top plate and a bottom plate of the syringe attachment device; ii) wherein a top portion of the syringe attachment device is exposed and the sterile cover surrounds the coupling portion of the syringe attachment device; and wherein the sterile cover is welded to, or bonded with an adhesive to, an outer perimeter of the base of the syringe attachment device.

12. The spray deposition system according to claim 1, wherein the spray deposition system further comprises a sterile cover, wherein the sterile cover i) has a cavity in which the handheld device is at least partially located; or ii) encloses the handheld device; or iii) has a first end which is closed and a second end which is open, wherein the second end is sealable; or iv) is a sheet open on all sides, wherein the handheld device is covered by the sheet and the sheet can be closed such that a seal is created between an interior of the sterile cover and an exterior of the sterile cover.

13. The spray deposition system according to claim 1, wherein the coupling portion of the syringe attachment device is monolithic to the handheld device.

14. The spray deposition system according to claim 1, wherein a portion of the spray deposition system is tolerant to ethylene oxide gas without any functional damage.

15. The spray deposition system according to claim 1, for use in treating a living being, wherein the syringe channel includes a syringe having a solution comprising an active substance which is configured for treating a living being.

Description

EXPLANATION TO THE FIGURES

[0064] Numbers close to a line having one arrow at each end are no reference signs, but actually indicate a length in millimeters (mm) between the two arrows. The same is true for numbers which are followed by the letter R, wherein in this case, the length in millimeters refers to the length of a radius of a circle in millimeters (mm). Numbers close to a curve and/or numbers followed by a degree sign)( do not indicate a length, but actually an angle. All other numbers are reference signs. A list of the reference signs is given below.

[0065] FIG. 1 shows a sideview of a syringe attachment device 1 of a spray deposition system according to the invention. The syringe attachment portion 1 has a base with a coupling portion 2 and a top portion 3 and comprises a syringe channel 4.

[0066] FIG. 2 shows s topview of a syringe attachment device 1 of a spray deposition system according to the invention. The base with the coupling portion 2 can be seen as well as the top portion 3 and the syringe channel 4.

[0067] FIG. 3 shows a frontview of a syringe attachment device 1 of a spray deposition system according to the invention. The base with a coupling portion 2 can be seen as well as the top portion 3 and the syringe channel 4. Additionally, the bottom surface 17 of the coupling portion 2 is illustrated.

[0068] FIG. 4 shows a backview of a syringe attachment device 1 of a spray deposition system according to the invention. Not only the base with a coupling portion 2, the top portion 3 and the syringe channel 4, but also the bottom surface 17 of the coupling portion 2 can be seen.

[0069] FIG. 5 shows a sideview of a handheld device 7 of a spray deposition system according to the invention. The handheld device 7 has a top portion 18 with an upper surface 8 and comprises a moveable slide 9, a plunger driver 21 and a feature 23 for engaging the coupling portion of the syringe attachment device.

[0070] FIG. 6 shows a topview of a handheld device 7 of a spray deposition system according to the invention. The moveable slide 9 and the upper surface 8 with the feature 23 for engaging the coupling portion of the syringe attachment device can be seen. Additionally, the topview of the plunger driver 21 can be seen.

[0071] FIG. 7 shows a frontview of a handheld device 7 of a spray deposition system according to the invention. On the top portion 18 of the handheld device 7, the moveable slide 9 and the upper surface 8 with the feature 23 for engaging the coupling portion of the syringe attachment device is illustrated. Additionally, the frontview of the plunger driver 21 is shown.

[0072] FIG. 8 shows a backview of a handheld device 7 of a spray deposition system according to the invention. The backview of the plunger driver 21 is illustrated.

[0073] FIG. 9 shows an assembled position of the spray deposition system according to the invention. The syringe attachment device 1 with its top portion 3 and syringe channel 4 is coupled to the handheld device 7 via its coupling portion 2. The coupled handheld device 7 and its plunger driver 21 are illustrated.

[0074] FIG. 10 shows a frontview (left) and a sideview (right) of an adaptor 10 of the spray deposition system according to the invention. The first opening 11, the second opening 12 and the third opening 13 of the adaptor 10 are shown. Additionally, the first fluid channel 15 and the second fluid channel 16 of the adaptor 10 are indicated.

[0075] FIG. 11 shows an assembled position of the spray deposition system according to the invention. The syringe attachment device 1 with its top portion 3 and syringe channel 4 is coupled to the handheld device 7 via its coupling portion. The coupled handheld device 7 and its plunger driver 21 are illustrated. The plunger driver 21 is engaged with a plunger 22 of a syringe 5. One end of a needle 14 is connected to the syringe 5 and the other end of the needle 14 is connected to the first opening of the adaptor 10. Further illustrated is the second opening 12 of the adaptor 10 which is in fluid connection with the surrounding environment (air). The third opening of the adaptor 10 is connected to a tube 6 which is configured to deliver an airflow to a first fluid channel of the adaptor 10. The tube 6 is fluidly coupled to an air filter 19 and an airflow indicator 20.

LIST OF REFERENCE SIGNS

[0076] 1: syringe attachment device; [0077] 2: coupling portion of syringe attachment device; [0078] 3: top portion of syringe attachment device; [0079] 4: syringe channel of syringe attachment device; [0080] 5: syringe; [0081] 6: tube configured to deliver an airflow; [0082] 7: handheld device; [0083] 8: upper surface of handheld device; [0084] 9: movable slide of handheld device; [0085] 10: adaptor of syringe attachment device; [0086] 11: first opening of adaptor; [0087] 12: second opening of adaptor; [0088] 13: third opening of adaptor; [0089] 14: needle; [0090] 15: first fluid channel; [0091] 16: second fluid channel; [0092] 17: bottom surface of coupling portion of syringe attachment device; [0093] 18: top portion of handheld device; [0094] 19: air filter (coupled to the tube configured to deliver an airflow); [0095] 20: airflow indicator (coupled to the tube configured to deliver an airflow); [0096] 21: plunger driver of movable slide of handheld device; [0097] 22: plunger of a syringe; [0098] 23: feature of handheld device for engaging coupling portion.