Method for Setting a Control Device or a Closed-Loop Control Device of a Blood Treatment Apparatus, and Devices

Abstract

A method for setting a control device or a closed-loop control device of a blood treatment apparatus, includes providing, determining or reading out a correction factor and correcting the flow value and/or the treatment target entered by the user by or about the correction factor. Furthermore, the present disclosure relates to a blood treatment apparatus, a digital storage medium, a computer program product, and a computer program.

Claims

1-14. (canceled)

15. A method for setting a control device of a blood treatment apparatus, the blood treatment apparatus comprising: a blood pump connectable to an extracorporeal blood circuit and configured to convey blood through the extracorporeal blood circuit; a dialysis liquid inlet line; a dialysis liquid pump configured to convey dialysis liquid through at least one of the dialysis liquid inlet line, an ultrafiltration pump flow, and an effluent pump; an input device configured to receive at least one of a flow value to be achieved or effected during an upcoming blood treatment session and a treatment target to be achieved by the completion of the upcoming blood treatment session, wherein the at least one of the flow value and the treatment target is achieved or effected by at least one of the blood pump, the dialysis liquid pump, the ultrafiltration pump flow, and the effluent pump; a reading device configured to read and store the at least one of the flow value and the treatment target; a control device configured for controlling or regulating the blood treatment apparatus after the start of the upcoming blood treatment session based on the at least one of the flow value and the treatment targets; and a storage device; the method comprising: a) providing, determining, or reading out a correction factor; and b) correcting the at least one of the flow value and the treatment target received by the input device, about or by the correction factor.

16. The method according to claim 15, wherein the correction factor is stored as a constant in the storage device and is provided by the storage device.

17. The method according to claim 15, wherein the treatment target is a treatment outcome or result relative to or over the treatment duration.

18. The method according to claim 15, wherein the correction factor is between 10% and 30%.

19. The method according to claim 15, wherein the correction factor effects a correction between 10% and 30%, of at least one of the flow value and the treatment target.

20. The method according to claim 15, wherein the correction factor is received by the input device.

21. A blood treatment apparatus comprising: a blood pump, connectable to an extracorporeal blood circuit and configured to convey blood through the extracorporeal blood circuit; a dialysis liquid inlet line; a dialysis liquid pump configured to convey dialysis liquid through at least one of the dialysis liquid inlet line, an ultrafiltration pump flow, and an effluent pump; an input device configured to receive at least one of a flow value to be achieved or effected during an upcoming blood treatment session and a treatment target to be achieved by the completion of the upcoming blood treatment session, wherein the at least one of the flow value and the treatment target is achieved or effected by at least one of the blood pump, the dialysis liquid pump, the ultrafiltration pump flow, and the effluent pump; a reading device configured to read and store the at least one flow value and treatment targets; a storage device; and a control device configured to control or regulate the blood treatment apparatus after the start of the upcoming blood treatment session based on the at least of the flow value and the treatment target; wherein the controller is configured to execute a method comprising: a) providing, determining, or reading out a correction factor; and b) correcting the at least one flow value or the treatment target received by the input device, about or by the correction factor.

22. The blood treatment apparatus according to claim 21, wherein the treatment target is a treatment outcome or result relative to or over the treatment duration.

23. The blood treatment apparatus according to claim 21, wherein the correction factor is stored as a constant in the storage device and is provided by the storage device.

24. The blood treatment apparatus according to claim 21, wherein the correction factor is between 10% and 30%.

25. The blood treatment apparatus according to claim 21, wherein the correction factor effects a correction between 10% and 30% of the at least one flow value and treatment target.

26. The blood treatment apparatus according to claim 21, wherein input device is configured to receive the correction factor.

27. The blood treatment apparatus according to claim 21, wherein the blood treatment apparatus is a peritoneal dialysis apparatus, hemodialysis apparatus, hemofiltration apparatus, hemodiafiltration dialysis apparatus, a chronic renal replacement therapy apparatus, or a continuous renal replacement therapy apparatus.

28. A digital storage medium with electronically readable control signals, configured to interact with a programmable computer system such that the machine-induced steps of a method comprising: a) providing, determining, or reading out a correction factor; b) correcting the at least one of a flow value and a treatment target received by the input device of a blood treatment apparatus, about or by the correction factor; wherein the blood treatment apparatus comprises: a blood pump, connectable to an extracorporeal blood circuit and configured to convey blood through the extracorporeal blood circuit; a dialysis liquid inlet line; a dialysis liquid pump configured to convey dialysis liquid through at least one of the dialysis liquid inlet line, an ultrafiltration pump flow, and an effluent pump; an input device configured to receive at least one of a flow value to be achieved or effected during an upcoming blood treatment session and a treatment target to be achieved by the completion of the upcoming blood treatment session, wherein the at least one of the flow value and the treatment target is achieved or effected by at least one of the blood pump, the dialysis liquid pump, the ultrafiltration pump flow, and the effluent pump; a reading device configured to read and store the at least one flow value and treatment targets; a storage device; and a control device configured to control or regulate the blood treatment apparatus after the start of the upcoming blood treatment session based on the at least of the flow value and the treatment target.

29. The digital storage medium according to claim 28, wherein the method further comprises: storing the correction factor as a constant in the storage device of the blood treatment apparatus.

Description

BRIEF DESCRIPTION OF THE FIGURES

[0064] The present invention is exemplarily explained below with regard to the accompanying drawings in which identical reference numerals refer to the same or similar components. The following applies:

[0065] FIG. 1 shows a simplified illustration of an embodiment of a blood treatment apparatus having an extracorporeal blood circuit;

[0066] FIG. 2 exemplarily shows a graphic illustration of the 24-hour course of a blood treatment session without using the method;

[0067] FIG. 3 shows a graphic illustration of the 24-hour course of a blood treatment session with an exemplary embodiment of the method; and

[0068] FIG. 4 shows the course of an exemplary embodiment of the method in a flow diagram.

DETAILED DESCRIPTION OF THE FIGURES

[0069] FIG. 1 shows a greatly simplified illustration of a blood treatment apparatus 1000, connected to an extracorporeal blood circuit 3000 and to an only roughly indicated discharge hose system having an optional effluent bag 4000. The extracorporeal blood circuit 3000 comprises a first line 3010, herein in the form of an arterial line section.

[0070] The first line 3010 is in fluid communication with a blood treatment device, herein a blood filter or dialyzer 3030 by way of example. The blood filter 3030 comprises a dialysis liquid chamber 3030a and a blood chamber 3030b, which are separated from each other by a mostly semi-permeable membrane 3030c.

[0071] The extracorporeal blood circuit 3000 further comprises at least a second line 3050, herein in the form of a venous line section or a return line. Both the first line 3010 and the second line 3050 may serve for connection to the vascular system of the patient who is not illustrated.

[0072] The first line 3010 is optionally connected to a (first) hose clamp 3020 for blocking or closing the line 3010. The second line 3050 is optionally connected to a (second) hose clamp 3060 for blocking or closing the line 3050.

[0073] The blood treatment apparatus 1000 which is represented, only by some of its devices and merely schematically, in FIG. 1, comprises a blood pump 1010. During the patient's treatment the blood pump 1010 conveys blood through sections of the extracorporeal blood circuit 3000 and towards the blood filter or dialyzer 3030. This is indicated by the small arrow tips, which are used in FIG. 1 to generally illustrate the direction of flow

[0074] Fresh dialysis liquid is pumped from a source 2000 along the dialysis liquid inlet line 1040 into the dialysis liquid chamber 3030a, by a pump 1210 for dialysis liquid, which may be designed as a roller pump or as an otherwise occluding pump. The dialysis liquid leaves the dialysis liquid chamber 3030a in the direction of the basin 6000, as dialysate possibly enriched by filtrate, and is herein referred to as effluent.

[0075] The source 2000 may be, for example a bag or a container. Further, the source 2000 may also be a fluid line from which the online and/or continuously generated or mixed liquid is provided, for example a hydraulic outlet or connection of the blood treatment apparatus 1000.

[0076] A further source 2010 with substitute may be optionally provided. It may correspond to the source 2000 or be a separate source.

[0077] At the bottom right of FIG. 1 is indicated where the discharge hose system with the effluent bag 4000 is connected to the blood treatment apparatus 1000.

[0078] In addition to the aforementioned blood pump 1010, the arrangement in FIG. 1 further comprises purely optionally a series of further pumps, in each case optional, namely the pump 1110 for substitute, the pump 1210 for dialysis liquid and the pump 1310 for the effluent.

[0079] The pump 1210 is provided to supply dialysis liquid, from a source 2000, for example a bag, via an optional existing bag heater with a bag H2 to the blood filter 3030, via a dialysis liquid inlet line 1040.

[0080] The thus supplied dialysis liquid exits from the blood filter 3030 via a dialysate outlet line 1020, supported by the pump 1310, and may be discarded.

[0081] Upstream of blood pump 1010 an optional arterial sensor PS1 is provided. During the patient's treatment it measures the pressure in the arterial line.

[0082] Downstream of the blood pump 1010, but upstream of the blood filter 3030 and if provided, upstream of a coupling site 25 for heparin, a further optional pressure sensor PS2 is provided. It measures the pressure upstream of the blood filter 3030 (pre-hemofilter).

[0083] Another further pressure sensor may be provided as PS4 downstream of the blood filter 3030, however preferably upstream of the pump 1310, in the dialysate outlet line 1020 to measure the filtrate pressure of the blood filter 3030.

[0084] Blood, which leaves the blood filter 3030, passes through an optional venous blood chamber 29, which may comprise a deaeration device 31 and which may be in fluid communication with a further pressure sensor PS3.

[0085] A control device or a closed-loop control device 1500 for controlling or regulating the blood treatment apparatus 1000 may be provided and may be in signal communication and/or control communication with all the a.m. components of the blood treatment apparatus 1000.

[0086] Furthermore, an input device 100, a reading device 150 and a storage device 160 are connected to the blood treatment apparatus 1000 in signal communication and/or control communication.

[0087] FIG. 2 shows a treatment result d (in [ml/kg*h]) over the time t (in [h]) upon completion of a common blood treatment session set for 24 hours for the acute treatment of the patient with two interruptions starting after 6 hours respectively after 17 hours. The interruptions can each be recognized by the drop of Q.sub.dia. Q.sub.dia corresponds to the flow of the dialysis pump 1210. Other pump flows, for instance Q.sub.B for the blood pump 1010, Q.sub.UF for the ultrafiltration pump or flows of the effluent pump may as well be affected by the interruptions.

[0088] The treatment result is also affected by both interruptions: d decreases further upon and during each interruption. This would require a regulating mechanism in order to achieve the desired treatment result d.sub.targ of 25 ml/kg*h until the completion or the end of the predetermined 24 hours.

[0089] As can be seen in FIG. 2, the set treatment target d.sub.targ is not reached after 24 hours due to both interruptions, because the actual achieved treatment result dart is less than d.sub.targ.

[0090] FIG. 3 shows the course of a blood treatment session with the same interruptions like in FIG. 2, herein however by using an exemplary embodiment of the method. The treatment target was automatically corrected upwards already before the beginning of the treatment session, i.e. at t less than or equal to 0, by a correction factor (here exemplarily by 20%). Pump flows and/or other machine parameters were raised to the new, higher, corrected treatment target d.sub.korr. Based thereon, the set, initial treatment target is achieved after 24 hours; d.sub.targ=d.sub.act applies.

[0091] FIG. 4 shows the course of an exemplary embodiment of the method in a flow diagram.

[0092] In this, S1 describes the input of the correction factor f.sub.korr or the reading out thereof from the storage device 160.

[0093] The step S2 describes the setting of the initial value d.sub.korr taking into consideration the correction factor f.sub.korr, added to the treatment target d.sub.targ.

[0094] Step S3 represents the running treatment over 24 hours, with interruptions of the treatment session.

[0095] Step S4 represents achieving the treatment target d.sub.targ at the end of the 24-hour treatment session, wherein preferably d.sub.act=d.sub.targ is achieved.

LIST OF REFERENCE NUMERALS

[0096] 25 addition site for heparin (optional) [0097] 29 venous blood chamber [0098] 31 deaeration device [0099] 100 input device [0100] 150 reading device [0101] 160 storage device [0102] 1000 blood treatment apparatus [0103] 1010 blood pump [0104] 1020 dialysate outlet line, effluent inlet line [0105] 1040 dialysis liquid inlet line [0106] 1110 pump for substituate [0107] 1210 dialysis liquid pump [0108] 1310 pump for dialysate or effluent [0109] 1500 control device or closed-loop control device [0110] 2000 dialysis liquid source [0111] 2010 substituate source, optional [0112] 3000 extracorporeal blood circuit [0113] 3010 first line (arterial line section) [0114] 3020 (first) hose clamp [0115] 3030 blood filter or dialyzer [0116] 3030a dialysis liquid chamber [0117] 3030b blood chamber [0118] 3030c semi-permeable membrane [0119] 3050 second line (venous line section) [0120] 3060 (second) hose clamp [0121] 4000 effluent bag [0122] 6000 basin [0123] H2 bag heating with bag (dialysis liquid) [0124] H1 bag heating with bag (substituate) [0125] PS1, PS2 arterial pressure sensor (optional) [0126] PS3 venous pressure sensor (optional) [0127] PS4 pressure sensor for measuring the filtrate pressure [0128] d.sub.act actually reached treatment result [0129] d.sub.targ set treatment target [0130] d.sub.korr corrected treatment target [0131] f.sub.korr correction factor, predetermined correction factor [0132] Q.sub.dia dialysis liquid pump flow [0133] Q.sub.B blood pump flow [0134] Q.sub.UF ultrafiltration pump flow