Injector
10926033 ยท 2021-02-23
Assignee
Inventors
Cpc classification
F42B3/04
MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
F42B12/54
MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
A61M5/30
HUMAN NECESSITIES
F42B3/006
MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
F15B15/19
MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
International classification
A61M5/20
HUMAN NECESSITIES
F42B12/54
MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
A61M5/30
HUMAN NECESSITIES
Abstract
An injector can include an ignition device having a partition member which forms a first space to store a gunpowder and which is formed of a prescribed rigid material such that the partition member is breached based on a rise in pressure of the first space when the gunpowder is burned. The injector can also include a case including a base section fixed on a side of the ignition device. The case can be arranged in a space inside the injector main body so as to cover the ignition device. The case can define a second space with the partition member of the ignition device and encapsulate, inside the second space, a combustion product of the gunpowder. When the gunpowder burns in the ignition device and pressure inside the second space rises, a part of the case extends so as to approach a prescribed end section.
Claims
1. An injector for injecting an injection objective substance into an injection target region, the injector comprising: an injector main body having a through-hole formed in an axial direction; a piston section arranged so as to be slidable inside the through-hole; a syringe section arranged on a tip side of the injector main body, the syringe section comprising a storage chamber configured to store the injection objective substance, a plunger configured to pressurize the injection objective substance inside the storage chamber as the piston section slides, and a nozzle section including a flow path through which the injection objective substance that is present inside the storage chamber and has been pressurized by the plunger flows, the nozzle configured to eject the injection objective substance from an ejection port formed at a tip of the flow path; an ignition device comprising a partition member which forms a first space to store a gunpowder and which is formed of a prescribed rigid material such that the partition member is breached based on a rise in pressure of the first space when the gunpowder is burned; and a case including a base section fixed on a side of the ignition device, the case arranged in a space inside the injector main body so as to cover the ignition device, the case defining a second space with the partition member of the ignition device and encapsulating, inside the second space, a combustion product generated by combustion of the gunpowder in the ignition device, wherein the case includes: an extending section configured to, based on a rise in pressure inside the second space by gunpowder combustion in the ignition device, extend in an approach direction in which a part of the case approaches a prescribed end section of the piston on a side opposite to an end section opposing the plunger; and a pressing section provided in the part of the case and configured to press the prescribed end section of the piston as the extending section extends, the injector further comprising a cushioning member provided on a prescribed inner wall surface which forms an internal space of the injector main body, the inner wall surface being in a vicinity of an end surface of the through-hole and opposing the part of the case, and when the extending section is extended by gun owder combustion in the inition device, the extending section comes into contact with the cushioning member and the extension of the extending section is stopped.
2. The injector according to claim 1, further comprising a gas generating agent stored inside the second space and configured to generate a prescribed gas by combustion, and wherein the extending section is configured such that the part of the case extends in the approach direction as pressure inside the second space rises in response to gunpowder combustion in the ignition device and combustion of the gas generating agent.
3. The injector according to claim 1, wherein the extending section is formed in a side wall section of the case opposing an inner wall surface that extends in an axial direction of the injector main body so as to be folded in a bellows shape in a state prior to gunpowder combustion in the ignition device, and wherein the extending section is configured so as to extend in the axial direction in response to gunpowder combustion in the ignition device.
4. The injector according to claim 1, wherein the part of the case is an end surface on a tip side of the case, and wherein an area of the tip-side end surface of the case is formed larger than an end surface area of the prescribed end section of the piston section.
5. The injector according to claim 1, wherein the part of the case is thicker than the remaining portions of the case.
6. The injector according to claim 1, wherein a reinforcing plate having a prescribed thickness is provided inside or outside the case in the part of the case.
7. The injector according to claim 1, wherein the case is arranged inside the injector main body so that the pressing section comes into contact with the prescribed end section of the piston section in a state prior to gunpowder combustion in the ignition device.
8. An injector for injecting an injection objective substance into an injection target region, the injector comprising: an injector main body having a through-hole formed in an axial direction; a piston section arranged so as to be slidable inside the through-hole; a syringe section arranged on a tip side of the injector main body, the syringe section comprising a storage chamber configured to store the injection objective substance, a plunger configured to pressurize the injection objective substance inside the storage chamber as the piston section slides, and a nozzle section including a flow path through which the injection objective substance that is present inside the storage chamber and has been pressurized by the plunger flows, the nozzle configured to eject the injection objective substance from an ejection port formed at a tip of the flow path; an ignition device comprising a partition member which forms a first space to store a gunpowder and which is formed of a prescribed rigid material such that the partition member is breached based on a rise in pressure of the first space when the gunpowder is burned; and a case including a base section fixed on a side of the ignition device, the case arranged in a space inside the injector main body so as to cover the ignition device, the case defining a second space with the partition member of the ignition device and encapsulating, inside the second space, a combustion product generated by combustion of the gunpowder in the ignition device, wherein the case includes: an extending section configured to, based on a rise in pressure inside the second space by gunpowder combustion in the ignition device, extend in an approach direction in which a part of the case approaches a prescribed end section of the piston on a side opposite to an end section opposing the plunger, and a pressing section provided in the part of the case and configured to press the prescribed end section of the piston as the extending section extends, and wherein the injector is configured such that, in a state where the extending section is extended to the maximum in response to gunpowder combustion in the ignition device, a prescribed gap is present between the pressing section of the part of the case and a prescribed inner wall surface opposing the pressing section and forming an internal space of the injector main body, the inner wall surface being in a vicinity of an end section of the through-hole and opposing the part of the case.
9. The injector according to claim 8, wherein the pressing section of the part of the case is larger in width than that of the prescribed end section of the piston.
10. The injector according to claim 8, wherein the internal space of the injector main body is larger in width than that of the prescribed end section of the piston.
11. The injector according to claim 8, wherein the internal space of the injector main body houses the case such that a sidewall section of the case does not contact an inner wall of the internal space of the injector main body facing the sidewall section of the case.
12. The injector according to claim 11, wherein an inner wall of the injector main body does not contact an outer wall of the internal space facing the inner wall of the injector main body.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1)
(2)
(3)
(4)
(5)
(6)
DETAILED DESCRIPTION
(7) Hereinafter, a needle-free injector 1 (hereinafter, simply referred to as an injector 1) without a needle will be described as an example of an injector according to an embodiment of the present invention with reference to the drawings. It is to be understood that configurations of the embodiment described below are illustrative and that the present invention is not limited to the configurations of the embodiment described below.
First Embodiment
(8)
(9) In this case, the injector 1 has an injector main body 2, and a syringe section 5 is arranged on a tip side of the injector main body 2. In addition, an initiator 20 that is an ignition device to be described later is arranged at another end section of the injector main body 2. An example of the initiator 20 will be described with reference to
(10) In this case, the initiator 20 is an electric ignition device, and a cup 21 (corresponding to the partition member according to embodiments of the present invention) of which a surface is covered by an insulating cover made of resin defines, inside the cup 21, a space 29 (corresponding to the first space according to embodiments of the present invention) for arranging a gunpowder 22. In addition, a metal header 24 is arranged in the space, and a cylindrical charge holder 23 is provided on an upper surface of the metal header 24. The gunpowder 22 is held by the charge holder 23. A bridge wire 26 which electrically connects one conductive pin 28 with the metal header 24 is arranged in a bottom section of the gunpowder 22. Two conductive pins 28 are fixed to the metal header 24 via an insulator 25 so as to be insulated from each other when voltage is not being applied. Furthermore, an opening of the cup 21 through which the two conductive pins 28 supported by the insulator 25 extend is protected by a resin collar 27 in a state where insulation between the conductive pin 28 is favorably maintained.
(11) In the initiator 20 configured as described above, when voltage is applied between the two conductive pins 28 by an external power source, a current flows through the bridge wire 26 and, accordingly, the gunpowder 22 burns. In this case, in an initial stage of combustion of the gunpowder 22 sealed in the space 29 that is an enclosed space formed by the cup 21 and the resin collar 27, the gunpowder 22 burns while the sealed state of the space 29 is maintained. The cup 21 is formed by a resin material and has certain rigidity and strength. Therefore, while a shape of the cup 21 is more or less maintained until pressure of the space 29 reaches prescribed pressure, once the pressure exceeds the prescribed pressure, a bottom surface section (an area opposing an opening of the charge holder 23) is breached as shown in
(12) Favorable examples of the gunpowder 22 used in the injector 1 include gunpowder (ZPP) containing zirconium and potassium perchlorate, gunpowder (THPP) containing titanium hydride and potassium perchlorate, gunpowder (TiPP) containing titanium and potassium perchlorate, gunpowder (APP) containing aluminum and potassium perchlorate, gunpowder (ABO) containing aluminum and bismuth oxide, gunpowder (AMO) containing aluminum and molybdenum oxide, gunpowder (ACO) containing aluminum and copper oxide, and gunpowder (AFO) containing aluminum and iron oxide, and gunpowder consisting of a combination of a plurality of these gunpowders. These gunpowders exhibit characteristics in that, while high-temperature and high-pressure plasma is generated during combustion immediately after ignition, generated pressure drops abruptly once the temperature drops to normal temperature and a combustive organism condenses since the gunpowders do not contain a gaseous component. It should be noted that gunpowders other than the above may be used as an ignition charge.
(13) Returning to
(14) In addition, a space 31 that is an internal space extending in an axial direction of the injector main body 2 is formed on a side of the initiator 20 inside the injector main body 2, and a through-hole 32 that is an internal space similarly extending in the axial direction of the injector main body 2 is formed on a side of the syringe section 5 inside the injector main body 2. The space 31 and the through-hole 32 are also an internal space that is continuously arranged inside the injector main body 2.
(15) Furthermore, the syringe section 5 provided on a tip side of the injector main body 2 has a syringe section main body 11 having, therein, a storage chamber 33 which stores an injection solution ML, the nozzle section 9 in which a flow path through which the injection solution flows is formed, and a nozzle holder 10 provided with the nozzle section 9. The nozzle holder 10 is attached to the syringe section main body 11 by a holder cap 12 so as to sandwich a gasket 13. In addition, the syringe section main body 11 is mounted by screwing to an end section of the injector main body 2 and, in the mounted state, the through-hole 32 inside the injector main body 2 and the storage chamber 33 inside the syringe section main body 11 become a continuous space. In the mounted state, the injection solution ML is liquid-tightly stored in the storage chamber 33 by a plunger 7, and the plunger 7 is exposed to a side of the through-hole 32. In this case, the plunger 7 is arranged so as to be slidable inside the storage chamber 33 and, due to sliding of the plunger 7, the injection solution ML is pressurized and ejection of the injection solution from the nozzle section 9 is performed. Furthermore, the plunger 7 is formed by a rubber member of which a surface is thinly coated by silicone oil so that the plunger 7 can smoothly slide inside the storage chamber 33.
(16) It should be noted that, in the nozzle holder 10, a single nozzle section 9 may be formed (refer to
(17) Next, a piston 6 made of metal is arranged in the through-hole 32 inside the injector main body 2 and the piston 6 is held so as to be slidable inside the through-hole 32. The piston 6 is formed in roughly a shape of a shaft extending along an axial direction of the through-hole 32, and has an end section (hereinafter, referred to as a first end section) 6a on a side of the space 31 and an end section (hereinafter, referred to as a second end section) 6b on a side of the syringe section 5 or, in other words, in contact with the plunger 7 arranged in the syringe section 5, and an O ring 6c is arranged around the piston 6 so that the piston 6 can smoothly slide inside the through-hole 32.
(18) An extending case 8 that is extended toward the first end section 6a of the piston 6 is fixed by a flange section 8a thereof to an end surface of an end section 2a of the injector main body 2 on a side of the initiator 20, and the extending case 8 is arranged in the space 31 inside the injector main body 2 so as to cover the cup 21 of the initiator 20. In addition, the extending case 8 and an outer surface of the cup 21 of the initiator 20 form a combustion chamber 34 (corresponding to the second space according to embodiments of the present invention) which is an enclosed space. Furthermore, a gas generating agent 40 which generates a prescribed gas by combustion is arranged inside the combustion chamber 34. Examples of the gas generating agent 40 include a single-base smokeless powder consisting of 98 percent by mass of nitrocellulose, 0.8 percent by mass of diphenylamine, and 1.2 percent by mass of potassium sulfate. Furthermore, various gas generating agents used in an airbag gas generator or a seat-belt pretensioner gas generator can also be used.
(19) The gas generating agent 40 burns as a combustion product of the combustion of the gunpowder 22 in the initiator 20 flows into the combustion chamber 34 from the opening of the cup 21 and the gas generating agent 40 is exposed to the combustion product, thereby generating the prescribed gas. It should be noted that the extending case 8 has sufficient strength to prevent the extending case 8 from being breached even by pressure inside the combustion chamber 34 created by the gas generating agent 40. Therefore, a state where the combustion product by the gunpowder 22 and the prescribed gas by the gas generating agent 40 are encapsulated inside the extending case 8 is maintained. With the gas generating agent 40, since the prescribed gas generated during combustion contains a gas component even at normal temperature, a drop rate of generated pressure is low. Furthermore, although a combustion completion time of the gas generating agent 40 during combustion is extremely long as compared to the gunpowder 22 described earlier, by adjusting dimensions or a size, a shape, and particularly a surface profile of the gas generating agent 40 when arranging the gas generating agent 40 inside the combustion chamber 34, the combustion completion time of the gas generating agent 40 can be changed. Adjusting an amount, a shape, or an arrangement of the gas generating agent 40 as described above enables generated pressure inside the combustion chamber 34 to be appropriately adjusted.
(20) In addition, the extending case 8 has a roughly hollow columnar shape, and a bottom section (corresponding to the pressing section according to embodiments of the present invention, and hereinafter referred to as a pressing bottom section) 8b of the extending case 8 on a side of the piston 6 is arranged inside the injector main body 2 in the state before ignition of the initiator 20 and in a state of being in contact with the first end section 6a of the piston 6. Furthermore, an inner wall surface of the injector main body 2 or, in other words, a side wall section of the extending case 8 opposing an inner wall surface of the space 31 is provided with a bellows section 8c (corresponding to the extending section according to embodiments of the present invention) which is extended toward the first end section 6a of the piston 6 by a pressure rise in the combustion chamber 34 attributable to a combustion product ejected from the opening of the cup 21 during combustion of the gunpowder 22 and to the prescribed gas generated from the gas generating agent 40 is burned by the combustion product. In addition, in the state before ignition, the bellows section 8c is arranged in folded state where the bellows section 8c is extensible toward the first end section 6a of the piston 6. An operation of the extending case 8 due to gunpowder combustion in the initiator 20 will be described later. Furthermore, a portion in the side wall section of the extending case 8 where the bellows section 8c is not provided or, in other words, a portion that does not extend will be referred as a non-extending section 8d.
(21) In the injector 1 configured as described above, when the gunpowder 22 burns in the initiator 20, a combustion product is generated and pressure inside the initiator 20 rises. Subsequently, when the pressure reaches the prescribed pressure described earlier, the bottom surface section of the cup 21 is breached and the combustion product is released into the combustion chamber 34 formed between the extending case 8 and the cup 21 and, at the same time, the gas generating agent 40 exposed to the combustion product burns and prescribed gas is generated. Since the combustion product and the prescribed gas are encapsulated in the combustion chamber 34, pressure inside the combustion chamber 34 rises with the generation of the prescribed gas. Accordingly, as the bellows section 8c extends, the pressing bottom section 8b presses the first end section 6a of the piston 6. As a result, pressure energy of the combustion chamber 34 is transferred to the piston 6, thereby pressurizing the injection solution inside the storage chamber 33. In this case, in the initiator 20, since the pressure rise inside the space 29 is not inhibited by an expansion of capacity of the space in which gunpowder combustion takes place as was the case in conventional art until the cup 21 is breached, the cup 21 does not significantly deform and the combustion product remains inside the space 29, thereby enabling the pressure inside the initiator 20 to promptly rise to prescribed pressure. This means that, in the gas generating agent 40 of which combustion is triggered by the combustion product, a combustion timing can be appropriately adjusted. In other words, by promptly raising the pressure inside the initiator 20, a timing at which the combustion product is supplied to the gas generating agent 40 by way of breaching the bottom surface section of the cup 21 can be adjusted to a desired timing suitable for ejection of the injection solution to the injection target region.
(22) A state where ejection of the injection solution is performed which is triggered by the combustion of the gunpowder 22 in the initiator 20 or, in other words, an ejection state of the injection solution in the injector 1 which is executed by an extending operation of the extending case 8 will be described with reference to
(23) Furthermore, in a state prior to combustion, a position of the pressing bottom section 8b of the extending case 8 is represented by X1. In addition, a position of the plunger 7 at this point is represented by P1. In this state, when the gunpowder 22 burns and the cup 21 is breached as described above, the pressure inside the combustion chamber 34 rises as the combustion product diffuses into the combustion chamber 34 and the gas generating agent 40 burns. As described earlier, the bellows section 8c of the extending case 8 is arranged in a folded state where the bellows section 8c is extensible toward the first end section 6a of the piston 6. Due to a pressure rise inside the combustion chamber 34, the bellows section 8c is extended toward the first end section 6a of the piston 6. At this point, the pressing bottom section 8b presses the first end section 6a of the piston 6. Therefore, an end surface of the first end section 6a of the piston 6 with which the pressing bottom section 8b comes into contact is an end surface which receives combustion energy of the gunpowder 22 and the gas generating agent 40. It should be noted that an area of the pressing bottom section 8b is designed larger than an area of the first end section 6a. Therefore, when the bellows section 8c is extended, the pressing bottom section 8b more reliably comes into contact with the first end section 6a of the piston 6 and the combustion energy described above can be transferred to the piston 6.
(24) Pressing by the pressing bottom section 8b causes the piston 6 to slide inside the through-hole 32. In addition, as the piston 6 slides, the plunger 7 presses the injection solution ML and, as a result, the injection solution ML is ejected to the injection target region from the nozzle section 9. In the ejection completion state where ejection of the injection solution ML has been completed, while the pressing bottom section 8b is in contact with the end surface of the first end section 6a of the piston 6 as shown in the lower half of
(25) In this manner, in the injector 1, during the process of combustion of the gunpowder 22, the pressing bottom section 8b of the extending case 8 is to move from the start position X1 in the state prior to combustion to the ejection position X2 in the ejection completion state. A distance of movement (X2X1) of the pressing bottom section 8b corresponds to a distance of movement (P2P1) of the plunger 7 for ejecting the injection solution ML. In addition, in the process of the movement, in the extending case 8, the bellows section 8c is extended and the pressing bottom section 8b moves while the combustion product generated by combustion of the gunpowder 22 and the prescribed gas generated by combustion of the gas generating agent 40 are kept encapsulated in the combustion chamber 34, and the combustion product remains encapsulated in the combustion chamber 34 even in the ejection completion state. By having the extending case 8 continuously encapsulate the combustion product in this manner, an effect of the combustion product and the like on the injection solution ML can be suppressed. Furthermore, in the injector 1, since combustion pressure generated by the combustion of the gunpowder 22 and the combustion of the gas generating agent 40 mainly vibrates the extending case 8, the injector main body 2 is less likely to be vibrated and vibration and noise from the injector main body 2 are reduced.
(26) In addition, the extending case 8 is configured so as to have a prescribed gap D with respect to an inner wall surface 31a which defines the space 31 inside the injector main body 2 and which is in a vicinity of an end section of the through-hole 32 even in the ejection completion state or, in other words, in a state where the extending case 8 is extended to the maximum. It should be noted that, in
(27) As described above, the injector 1 according to the present embodiment suppresses effects of a combustion product and a prescribed gas on the injection solution ML and, at the same time, enables the injection solution ML to be preferably pressurized.
(28) Modifications
(29) While the extending case 8 is arranged inside the injector main body 2 in a state where the pressing bottom section 8b is in contact with the first end section 6a of the piston 6 in the state prior to combustion in the embodiment described above, in an alternative aspect, the extending case 8 may be arranged inside the injector main body 2 in a state where the pressing bottom section 8b is separated from the first end section 6a of the piston 6 in the state prior to combustion as shown in
(30) In addition, while the gas generating agent 40 is stored in the combustion chamber 34 in the embodiment described above, even in an alternative aspect in which the gas generating agent 40 is not stored in the combustion chamber 34, since the pressure rise inside the space 29 is not inhibited by an expansion of capacity of the space in which gunpowder combustion takes place until the cup 21 is breached, the pressure inside the initiator 20 promptly rises to prescribed pressure. As a result, combustion energy of the gunpowder 22 can be effectively generated, the combustion energy can be promptly transferred to the piston 6, and pressurization of the injection solution ML can be performed in a preferable manner. Furthermore, at the same time, since the combustion product continues to be encapsulated by the extending case 8, an effect of the combustion product on the injection solution ML and combustion noise can be suppressed.
Second Embodiment
(31) Next, a second embodiment of the injector 1 will be described with reference to
(32) When combustion of the gunpowder 22 in the initiator 20 and combustion of the gas generating agent 40 occur, the bellows section 8c is extended. Accordingly, the pressing bottom section 8b presses the piston 6 via the first end section 6a. When the bellows section 8c becomes fully extended or before the bellows section 8c is fully extended, the pressing bottom section 8b comes into contact with the inner wall surface 31a via the cushioning member 41 to inhibit the extension of the bellows section 8c. Accordingly, a pressing action on the piston 6 via the extending case 8 is to be stopped. Even in this configuration, effects of a combustion product and a prescribed gas on the injection solution ML can be suppressed and, at the same time, the injection solution ML can be preferably pressurized. Furthermore, since the pressing bottom section 8b is capable of reducing, by coming into contact with the cushioning member 41, an impact received from the side of the inner wall surface 31a during the contact, the extending case 8 is less likely to be damaged, a preferable encapsulation of the combustion product and the like can be realized, and since vibration imparted to the injector main body 2 by the impact is suppressed, vibration and noise from the injector main body 2 are reduced.
Third Embodiment
(33) A third embodiment of the injector 1 will now be described. As described above, in the injector 1 according to embodiments of the present invention, the piston 6 is pressed as the extending case 8 extends. Therefore, in order to maintain an encapsulated state of the combustion product of the gunpowder 22 and the prescribed gas of the gas generating agent 40 in the combustion chamber 34 in a preferable manner, strength of the pressing bottom section 8b of the extending case 8 is favorably increased in consideration of the fact that transfer energy to the piston acts on the pressing bottom section 8b. In consideration thereof, a case thickness of the pressing bottom section 8b may be formed thicker than a case thickness of the non-extending section 8d in the side wall section of the extending case 8.
(34) In addition, alternatively, as shown in
Other Embodiments
(35) With the injector 1 according to embodiments of the present invention, in addition to cases where the injection solution described above is injected into a skin structure, for example, in the field of regenerative medicine with respect to humans, cultured cells, stem cells, and the like can be seeded to cells or scaffold tissue/scaffolds to be used as injection targets. For example, as described in Japanese Patent Application Laid-open No. 2008-206477, cells which can be appropriately determined by a person skilled in the art in accordance with a site of implantation and a purpose of recellularization such as endothelial cells, endothelial progenitor cells, bone marrow cells, preosteoblasts, chondrocytes, fibroblasts, skin cells, muscle cells, liver cells, kidney cells, intestinal cells, stem cells, and any other cells considered in the field of regenerative medicine can be injected by the injector 1. More specifically, prescribed cells are injected and transplanted into a region of transplantation by storing a liquid containing cells to be seeded (a cellular suspension) in the storage chamber 33 and pressurizing the liquid.
(36) In addition, the injector 1 according to embodiments of the present invention can also be used to deliver DNA or the like to cells, scaffold tissue/scaffolds, and the like such as described in Japanese Translation of PCT Application No. 2007-525192. In this case, since the use of the injector 1 according to embodiments of the present invention enables an effect on the cells, scaffold tissue/scaffolds, and the like to be suppressed as compared to delivery using a needle, it can be said that the use of the injector 1 according to embodiments of the present invention is more favorable.
(37) Furthermore, the injector 1 according to embodiments of the present invention can also be used when directly delivering various genes, cancer suppressor cells, a lipid envelope, or the like to object tissue or when administering an antigen gene in order to improve immunity to pathogens. Moreover, the injector 1 can also be used in various fields of disease treatment (the fields described in Japanese Translation of PCT Application No. 2008-508881, Japanese Translation of PCT Application No. 2010-503616, and the like), the field of immunological medicine (the field described in Japanese Translation of PCT Application No. 2005-523679), and the like, and fields in which the injector 1 is usable are not intentionally limited.