DEVICE AND METHOD FOR CHANGING AN IMPLANTED LENS

Abstract

A device for altering an optical and/or mechanical property of a lens that is implanted in an eye, the device including a laser device, which has a laser beam source that provides a pulsed laser beam and an optical unit, which impinges on the implanted lens with the pulsed laser beam. The device also includes a control device, which controls the laser device such that the optical and/or mechanical property of the lens is altered on the basis of non-linear interaction between the laser beam and the lens material.

Claims

1. (canceled)

2. A method for changing an optical property of an intraocular lens implanted into an eye, said method comprising: measuring a deviation of at least one optical property of the implanted intraocular lens from a predetermined value; determining a required change of the optical property of the implanted intraocular lens to reduce the measured deviation, applying pulsed laser radiation to the implanted intraocular lens, said radiation being applied such that the required change of the optical property is caused by nonlinear interaction between the pulsed laser radiation and material of the implanted intraocular lens; and applying the pulsed laser radiation at a power density at which two photon or multiple photon absorption occurs in the material of the implanted intraocular lens and below a threshold above which optical breakthroughs appear in the material of the implanted intraocular lens.

3. The method as claimed in claim 2, wherein the material of the implanted intraocular lens is characterized by a threshold for optical breakthrough, wherein an optical breakthrough occurs if the power density of the radiation applied to the implanted intraocular lens exceeds the threshold, and wherein the pulsed laser radiation is applied to the implanted intraocular lens such that the power density of the radiation does not exceed the threshold.

4. The method as claimed in claim 2, further comprising applying laser radiation at a pulse duration of less than one picosecond.

5. The method as claimed in claim 2, further comprising applying laser radiation at a pulse duration of less than 500 femtoseconds.

6. The method as claimed in claim 2, further comprising applying laser radiation at a pulse duration of less than 100 femtoseconds.

7. The method as claimed in claim 2, further comprising applying laser radiation with a wavelength of greater than 750 nm.

8. The method as claimed in claim 2, further comprising spatially modulating the pulsed laser radiation and then imaging the pulsed laser radiation onto the implanted intraocular lens.

9. The method as claimed in claim 2, further comprising focusing the pulsed laser radiation into the implanted intraocular lens, and moving the focus within the lens.

10. The method as claimed in claim 2, wherein the non-linear interaction between the laser radiation and the material of the implanted intraocular lens leads to a change in cross-linking of the material of the implanted intraocular lens resulting in a change in refractive index of at least a portion of the implanted intraocular lens.

11. The method as claimed in claim 2, further comprising measuring a residual deviation of at least one optical property of the implanted intraocular lens from the predetermined value after an irradiating step is carried out in which the pulsed laser radiation is applied to the implanted intraocular lens.

12. The method as claimed in claim 11, further comprising applying the pulsed laser radiation is carried out depending on the measured residual deviation.

13. The method as claimed in claim 2, further comprising selecting the wavelength of the pulsed laser radiation in the near-infrared range such that the wavelength of the pulsed laser radiation is approximately n times the wavelength of the UV absorption edge of the implanted intraocular lens material used with n being an integer greater than 1.

14. The method as claimed in claim 2, wherein the lens is implanted into the eye prior to the measuring step.

15. The method as claimed in claim 2, further comprising applying laser radiation with an intensity which is 10 to 100 times lower than the intensity required to produce optical breakthroughs in the material of the implanted intraocular lens.

16. A device for changing an optical property of an intraocular lens implanted into an eye, said device comprising: a laser device including a laser radiation source providing pulsed laser radiation and an optical unit applying said pulsed laser radiation to the implanted intraocular lens, as well as a control device, which controls the laser device such that a change of the optical lens property is effected due to a nonlinear interaction between the laser radiation and the material of the lens; and wherein the control device controls the laser device to apply the pulsed laser radiation at a power density at which two photon or multiple photon absorption occurs in the material of the implanted intraocular lens and below a threshold above which optical breakthroughs appear in the material of the implanted intraocular lens.

17. The device as claimed in claim 16, characterized by a threshold for optical breakthrough, wherein an optical breakthrough occurs if the power density of the radiation applied to the implanted intraocular lens exceeds the threshold, and wherein the pulsed laser radiation is applied to the implanted intraocular lens such that the power density of the radiation does not exceed the threshold.

18. The device as claimed in claim 16, wherein the laser radiation source provides the laser radiation with a wavelength of greater than about 750 nm.

19. The device as claimed in claim 16, wherein the laser radiation source provides the laser radiation with a pulse duration of less than one picoseconds.

20. The device as claimed in claim 16, wherein the laser radiation source provides the laser radiation with a pulse duration of less than about 500 femtoseconds.

21. The device as claimed in claim 16, wherein the laser radiation source provides the laser radiation with a pulse duration of less than about 100 femtoseconds.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The invention will be explained in more detail below, by way of example and with reference to the drawings, wherein:

[0025] FIG. 1 shows a schematic view of a first embodiment of the device according to the invention, and

[0026] FIG. 2 shows a schematic representation of a second embodiment of the device according to the invention.

[0027] While various embodiments are amenable to various modifications and alternative forms, specifics thereof have been shown by way of example in the drawings and will be described in detail. It should be understood, however, that the intention is not to limit the claimed inventions to the particular embodiments described. On the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the subject matter as defined by the claims.

DETAILED DESCRIPTION

[0028] The device for changing an optical and/or mechanical property of a lens implanted into an eye comprises a laser device 1 containing a laser radiation source 2. In this example, the laser radiation source 2 is a TiSa laser, which emits laser pulses S having a wavelength of 780 nm and a pulse duration of 10 fs. The pulse shape and, in particular, the pulse duration can be set by spatially splitting the spectral components of a generated pulse and then providing different optical path lengths for the spatially split spectral components of the pulse and subsequently combining the spectral components in space. Such a procedure is described, for example, in T. Baumert et al., Applied Physics B 65, pages 779-782, 1997, Femtosecond pulse shaping by an evolutionary algorithm with feedback and in T. Brixner et al., Applied Physics B70 [Suppl.], pages 119-124, 2000, Feedback-controlled femtosecond pulse shaping. The contents of both publications are herewith incorporated by reference in the present application.

[0029] Further, the laser device 1 contains an optical unit 3, which is arranged following the laser radiation source 2 and which focuses (S1, S2) the laser radiation S from the laser radiation source 2 and can deflect said radiation in three spatial directions. The schematic view of FIG. 1 shows two different focus positions P1 and P2 within an intraocular lens 4. The intraocular lens is already implanted into the eye (not shown).

[0030] The device further comprises a control device 5, which controls the laser device 1 such that a non-linear optical interaction occurs at the focal points P1, P2. Now, the laser device 1 is controlled such that, due to the non-linear interaction at the points P1 and P2, the desired change of the optical and/or mechanical lens property occurs. The optical lens property may be, for example, the refractive index of the lens. The mechanical property of the lens may be, for example, its shape and/or its rigidity or elasticity. The lens may consist of one single material or of several materials. In particular, the lens may contain a material showing a structural change and/or a change in cross-linking due to the non-linear interaction.

[0031] Particularly suitable lens materials are such materials whose absorption edge on the short-wavelength side of the visible spectrum (i.e. the UV absorption edge) is at approximately the 1/n.sup.th wavelength of the laser radiation used. In many cases, such materials have a relatively large effective cross-section of n-photon absorption. Of course, the corresponding wavelength of the laser radiation may also be selected in the near-infrared range, depending on the UV absorption edge of the lens material used, such that it is n times the wavelength of the UV absorption edge (with n being an integer greater than 1).

[0032] The interaction may be effected such that no optical breakthroughs occur yet. In this case, a very precise change of the lens property is possible. As an alternative, it is possible to select the intensity of the laser radiation such that optical breakthroughs do occur.

[0033] The device preferably also comprises a measuring device 6 by which the imaging properties of the implanted lens 4 can be measured, as schematically indicated by the cone beam D. After carrying out the measurement of the imaging properties, the desired correction or change, respectively, is then calculated (e. g. by the control device) and is then carried out by means of the device for changing an optical and/or mechanical property of the intraocular lens.

[0034] FIG. 2 shows another embodiment of the device. This embodiment differs from the device of FIG. 1 in that no laser beam is deflected, thus moving a focal point within the intraocular lens 4, but a spatially modulated laser beam S3 is imaged onto the lens 4 by means of the optical unit 3 so that the change of the optical and/or mechanical property of the intraocular lens 4 is carried out at once.

[0035] In order to carry out the method for changing an optical and/or mechanical property of a lens implanted into an eye, the intraocular lens 4 implanted into the eye is measured first, according to one embodiment, so as to detect patient-specific aberrations caused, for example, by individual deviations of the cornea from its ideal shape or by positioning errors of the implanted lens. Thus, this measurement allows to determine the deviation of at least one optical property of the implanted lens from a predetermined desired value. Depending on the deviation, the required change of an optical and/or mechanical property of the intraocular lens 4 is then determined. This determining step may be carried out, for example, by the measuring device 6, the control device 5 or another computer not shown. The data are then provided to the control unit 5, unless the control unit 5 has effected said determination itself, which then controls the laser device 1 such that the desired non-linear optical interaction between the pulsed laser radiation and the material of the intraocular lens occurs. Since the laser radiation used is in the infrared range, damage to the cornea as well as to the rest of the eye can be safely avoided.

[0036] Of course, it is also possible to perform the above-described steps (namely measuring step, determining step, irradiating step) several times in succession in order to achieve an optimum correction, if possible.

[0037] Further, prior to the first measuring step, the method may also include the step of implanting the lens into the eye.

[0038] Various embodiments of systems, devices, and methods have been described herein. These embodiments are given only by way of example and are not intended to limit the scope of the claimed inventions. It should be appreciated, moreover, that the various features of the embodiments that have been described may be combined in various ways to produce numerous additional embodiments. Moreover, while various materials, dimensions, shapes, configurations and locations, etc. have been described for use with disclosed embodiments, others besides those disclosed may be utilized without exceeding the scope of the claimed inventions.

[0039] Persons of ordinary skill in the relevant arts will recognize that the subject matter hereof may comprise fewer features than illustrated in any individual embodiment described above. The embodiments described herein are not meant to be an exhaustive presentation of the ways in which the various features of the subject matter hereof may be combined. Accordingly, the embodiments are not mutually exclusive combinations of features; rather, the various embodiments can comprise a combination of different individual features selected from different individual embodiments, as understood by persons of ordinary skill in the art. Moreover, elements described with respect to one embodiment can be implemented in other embodiments even when not described in such embodiments unless otherwise noted.

[0040] Although a dependent claim may refer in the claims to a specific combination with one or more other claims, other embodiments can also include a combination of the dependent claim with the subject matter of each other dependent claim or a combination of one or more features with other dependent or independent claims. Such combinations are proposed herein unless it is stated that a specific combination is not intended.

[0041] Any incorporation by reference of documents above is limited such that no subject matter is incorporated that is contrary to the explicit disclosure herein. Any incorporation by reference of documents above is further limited such that no claims included in the documents are incorporated by reference herein. Any incorporation by reference of documents above is yet further limited such that any definitions provided in the documents are not incorporated by reference herein unless expressly included herein.

[0042] For purposes of interpreting the claims, it is expressly intended that the provisions of 35 U.S.C. 112(f) are not to be invoked unless the specific terms means for or step for are recited in a claim.