Compact telescope configurations for light scanning systems and methods of using the same
10835119 ยท 2020-11-17
Assignee
Inventors
- Joseph A. Izatt (Durham, NC, US)
- Francesco Larocca (Durham, NC, US)
- Theodore Dubose (Durham, NC, US)
- Derek Nankivil (Durham, NC, US)
Cpc classification
A61B3/12
HUMAN NECESSITIES
International classification
A61B3/12
HUMAN NECESSITIES
A61B3/10
HUMAN NECESSITIES
Abstract
Compact telescope configurations for light scanning systems and related methods are disclosed. According to an aspect, a system for imaging or relaying an image of an object includes a first optical element having a first focal length f.sub.1 for imaging or relaying an image of an object at the distance f.sub.1 from the first optical element. The system also includes a second optical element having a second focal length f.sub.2 for receiving an image of the object from the first optical element and for focusing an output of the image at the distance f.sub.2 from the second optical element on a side that opposes the first optical element. The first optical element and the second optical element are separated by a distance of approximately [Formula I], wherein r is the finite radius of curvature of the wavefront of light located at the object or image of the object.
Claims
1. A system comprising: an optical coherence tomography (OCT) probe including a light scanner for imaging an object; a first optical element having a first focal length f.sub.1 for imaging or relaying an image of the object at the distance f.sub.1 from the first optical element; a second optical element having a second focal length f.sub.2 and having an optical axis substantially aligned with an optical axis of the first optical element for receiving an image of the object from the first optical element and for focusing an output of the image at the scanner at the distance f.sub.2 from the second optical element on a side that opposes the first optical element; and wherein the first optical element and the second optical element are separated by a distance d, wherein d is defined as a distance of 5% of
2. The system of claim 1, wherein the optical elements are lenses.
3. The system of claim 1, wherein the first optical element and the second optical element are biconvex lenses.
4. The system of claim 1, wherein the first optical element is a biconvex lens.
5. The system of claim 4, further comprising a plano-concave lens positioned between the first optical element and the second optical element, and having an optical axis substantially aligned with the optical axes of the first and second optical elements.
6. The system of claim 1, further comprising an eye positioned at the distance f.sub.2 from the second lens.
7. The system of claim 1, wherein the light scanner is a microelectromechanical system (MEMS) scanner.
8. The system of claim 1, wherein the light scanner is operably connected to scanning laser ophthalmoscopy (SLO) equipment for imaging the subject.
9. The system of claim 1, wherein the light scanner is operably connected to scanning optical coherence tomography (OCT) equipment for imaging the subject.
10. The system of claim 1, wherein the light scanner is operably connected to scanning optical coherence tomography (OCT) equipment and laser ophthalmoscopy (SLO) equipment for imaging the subject.
11. The system of claim 1, wherein r is between 0 and infinity.
12. The system of claim 11, wherein r is between the value of
13. The system of claim 1, further comprising a field flattening element to reduce field curvature induced by the system design.
14. The system of claim 13, wherein a field flattening element is located near an intermediate focal or image plane.
15. The system of claim 13, wherein a field flattening element is the closest optical element surface to an intermediate focal or image plane.
16. The system of claim 1, wherein the first and second elements are combined into a single optical element with focal length
17. The system of claim 1, wherein the first optical element and the second optical element are meniscus lenses.
18. The system of claim 17, further comprising one meniscus and two biconvex lenses positioned between the first optical element and the second optical element, and having an optical axis substantially aligned with the optical axes of the first and second optical elements.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1) The foregoing aspects and other features of the present subject matter are explained in the following description, taken in connection with the accompanying drawings, wherein:
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DETAILED DESCRIPTION
(14) For the purposes of promoting an understanding of the principles of the present disclosure, reference will now be made to various embodiments and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the disclosure is thereby intended, such alteration and further modifications of the disclosure as illustrated herein, being contemplated as would normally occur to one skilled in the art to which the disclosure relates.
(15) Articles a and an are used herein to refer to one or to more than one (i.e. at least one) of the grammatical object of the article. By way of example, an element means at least one element and can include more than one element.
(16) In this disclosure, comprises, comprising, containing and having and the like can have the meaning ascribed to them in U.S. Patent law and can mean includes, including, and the like; consisting essentially of or consists essentially likewise has the meaning ascribed in U.S. Patent law and the term is open-ended, allowing for the presence of more than that which is recited so long as basic or novel characteristics of that which is recited is not changed by the presence of more than that which is recited, but excludes prior art embodiments.
(17) Ranges provided herein are understood to be shorthand for all of the values within the range. For example, a range of 1 to 50 is understood to include any number, combination of numbers, or sub-range from the group consisting 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50.
(18) Unless specifically stated or obvious from context, as used herein, the term about is understood as within a range of normal tolerance in the art, for example within 2 standard deviations of the mean. The term about can be understood as within 10%, 9%, 8%, 7%, 6%, 5%, 4%, 3%, 2%, 1%, 0.5%, 0.1%, 0.05%, or 0.01% of the stated value. Unless otherwise clear from context, all numerical values provided herein are modified by the term about.
(19) Unless otherwise defined, all technical terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs.
(20) In accordance with embodiments of the disclosed subject matter, compact light scanning systems are provided that utilize a converging beam prior to the scanner to minimize the empty space within the telescope and field correcting optics to compensate for optical aberrations. In accordance with embodiments, the systems can be used as part of a combined scanning laser ophthalmoscopy and optical coherence tomography handheld probe. As a result of the presently disclosed subject matter, the size of telescopes in light scanning systems can be significantly reduced by minimizing the empty space within the telescope and correcting for the resulting error optically both before and after the light scanner.
(21) Systems and methods disclosed herein may be used in, for example, bar scanners, laser printers, endoscopes, confocal microscopes, SLO, OCT systems, and other devices that utilize both telescopes or beam expanders and light scanning. This compact design in a light scanner can be important for reducing the size of such equipment. These compact designs can facilitate better portability and increased comfort for the operator.
(22) Compact telescope design can be especially important for retinal imaging modalities, such as SLO and OCT, when developing handheld probe designs. Because of limitations in the aperture size of current high-speed 2D scanning mirrors, large magnifications are often necessary to optimize the imaging resolution at the retina. Some traditional methods of reducing telescope size while preserving magnification require reducing the focal lengths of the optics used in the telescope by a constant factor. However, practical constraints such as the minimum working distance from the light scanner to the telescope and from the telescope to the eye can pose fundamental limits to the extent to which the focal lengths of the telescope optics can be decreased. The presently disclosed subject matter can be used to further reduce the telescope size beyond that possible by simply reducing the focal lengths of the telescope optics. Further, the presently disclosed subject matter can also be applied to any suitable telescope between two light scanners that serve to image one scanner on to the other.
(23) As referred to herein, an optical element may be any suitable component for manipulating light. For example, an optical element may be a lens. In other examples, a refractive optical element may include dioptrics, catoptrics, catadioptrics, diffractive optics, the like and any combination thereof. Also, it should be understood that when a particular optical element (e.g., a lens) is referred to herein, then any other suitable one or more optical elements may replace the particular optical element for achieving the same function as will be understood by those of skill in the art.
(24) As referred to herein, a light scanner may be any suitable component for scanning light. For example, a scanner may be a 2D microelectromechanical system (MEMS) scanner. In other examples, a light scanner may be a galvanometric scanner, resonant scanner, reflective polygon scanner, rotating prism scanner, optical phased array, the like, or any combination thereof. Also, it should be understood that when a particular light scanner (e.g., a MEMS scanner) is referred to herein, then any other suitable one or more light scanners may replace the particular optical element for achieving the same function as will be understood by those of skill in the art.
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In this case,
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(28) By approximating L1 and L2 as thin, paraxial lenses, the following expression for the total length of the telescope l can be derived:
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By normalizing this expression by the total length of a 4f telescope, 2f.sub.1+2f.sub.2, a general expression for the fractional length of the telescope, L, can be derived:
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where R=r/f.sub.1 (normalized radius of curvature) and M=f.sub.2/f.sub.1 (lateral magnification of the telescope). A plot of the latter term in this equation, the fractional reduction in telescope length, is shown in
(31) However, if purely paraxial lenses are used, a small value of r induces a high field curvature. In the previous work, the field curvature was induced intentionally, but for many imaging systems field curvature is undesirable as it leads to regions of the image being out of focus. To quantify the degradation of the image, consider a Gaussian input beam of diameter D. The beam can converge after a distance r, giving it a divergence angle of
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and therefore a Rayleigh range of
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The image can be said to be out of focus if the beam is scanned to an angle .sub.max such that the focus of the scanned beam is a Rayleigh range away from the focus of the unscanned beam. The expression for .sub.max is:
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A plot of .sub.max versus r for a variety of input beam diameters is shown in
(35) If the application calls for a scan angle greater than .sub.max or the scan is within .sub.max but the blur at the edges of the image is too great, additional optics can be introduced to reduce the field curvature. One method for reducing field curvature is to simply introduce a zero-power field flattening lens into the system. If r<f.sub.1, there can be a focal plane between the scanner and L1; otherwise, there can be a focal plane between L1 and L2. Typically, the field flattener (an example location of which is represented by box 120 in
(36) A second method to remove field curvature may be to design custom optics for L1 that incorporate focusing power, aberration correction, and field flattening in a low number of elements. Although custom optics are a more expensive option, this approach will result in the lowest total amount of aberration (including field curvature).
(37) A compact telescope design in accordance with embodiments disclosed herein may be used to prototype an SLO and OCT handheld probe. For example,
(38) SLO images were acquired at 14.8 frames per second (fps) with 500 lines per frame and 675 pixels per line by using a 5 MHz digitizer, applying a 3.7 kHz sinusoidal waveform to the fast axis of the MEMS scanner, and utilizing both the forward and backward sweeps of the sinusoidal scan as separate lines in the frame. For OCT imaging, B-scans were acquired at 40 fps with 500 A-scans/B-scan and 2048 pixels/A-scan, by using a 20 kHz A-scan rate (limited by the speed of the spectrometer) and a 40 Hz sawtooth waveform to the fast axis of the MEMS scanner.
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(40) With continued reference to
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(42) At the smaller FOV, the SLO visualized parafoveal cones as close as a 3.8 eccentricity without adaptive optics. OCT images were acquired at a 6.4 FOV as shown in the image labeled D in
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(45) The presently disclosed subject matter provides, for example, a compact telescope design for constructing very compact SLO and OCT handheld probes with high imaging quality. A system in accordance with the present disclosure may be used for reducing the size of other devices that utilize both telescopes and light scanning such as bar scanners, laser printers, endoscopes, confocal microscopes, and the like.
(46) In accordance with embodiments of the present disclosure,
(47) The various techniques described herein may be implemented with hardware or software or, where appropriate, with a combination of both. Thus, the methods and apparatus of the disclosed embodiments, or certain aspects or portions thereof, may take the form of program code (i.e., instructions) embodied in tangible media, such as floppy diskettes, CD-ROMs, hard drives, or any other machine-readable storage medium, wherein, when the program code is loaded into and executed by a machine, such as a computer, the machine becomes an apparatus for practicing the presently disclosed subject matter. In the case of program code execution on programmable computers, the computer will generally include a processor, a storage medium readable by the processor (including volatile and non-volatile memory and/or storage elements), at least one input device and at least one output device. One or more programs may be implemented in a high level procedural or object oriented programming language to communicate with a computer system. However, the program(s) can be implemented in assembly or machine language, if desired. In any case, the language may be a compiled or interpreted language, and combined with hardware implementations.
(48) The described methods and apparatus may also be embodied in the form of program code that is transmitted over some transmission medium, such as over electrical wiring or cabling, through fiber optics, or via any other form of transmission, wherein, when the program code is received and loaded into and executed by a machine, such as an EPROM, a gate array, a programmable logic device (PLD), a client computer, a video recorder or the like, the machine becomes an apparatus for practicing the presently disclosed subject matter. When implemented on a general-purpose processor, the program code combines with the processor to provide a unique apparatus that operates to perform the processing of the presently disclosed subject matter.
(49) Features from one embodiment or aspect may be combined with features from any other embodiment or aspect in any appropriate combination. For example, any individual or collective features of method aspects or embodiments may be applied to apparatus, system, product, or component aspects of embodiments and vice versa.
(50) While the embodiments have been described in connection with the various embodiments of the various figures, it is to be understood that other similar embodiments may be used or modifications and additions may be made to the described embodiment for performing the same function without deviating therefrom. Therefore, the disclosed embodiments should not be limited to any single embodiment, but rather should be construed in breadth and scope in accordance with the appended claims. One skilled in the art will readily appreciate that the present subject matter is well adapted to carry out the objects and obtain the ends and advantages mentioned, as well as those inherent therein. The present examples along with the methods described herein are presently representative of various embodiments, are exemplary, and are not intended as limitations on the scope of the present subject matter. Changes therein and other uses will occur to those skilled in the art which are encompassed within the spirit of the present subject matter as defined by the scope of the claims.