NEW DELIVERY SYSTEM

Abstract

The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.

Claims

1. Delivery system consisting of (a) a solid core, which comprises at least one water-soluble vitamin, and (b) an inner coating comprising at least one fermentable biopolymer, which is crosslinked, and (c) an outer coating which is resistant to stomach conditions and releasing in the small intestine.

2. Delivery system according to claim 1, wherein the solid core comprises vitamin B2.

3. Delivery system according to claim 1, wherein the material of the inner coating is chosen from group consisting of alginate, chitosan, pectin, cyclodextrin as well as other gums.

4. Delivery system according to claim 1, wherein the inner coating layer is crosslinked with Mg and/or Ca ions.

5. Delivery system according to claim 1, wherein the outer coating is chosen from group consisting of shellac, methacrylate copolymers and fats.

6. Process of production delivery systems according to claim 1, wherein the process is carried out batchwise.

7. Process of production delivery systems according to claim 1, wherein the process is carried out continuously.

8. Process for the production of a premix, dietary supplement, food product, feed product, personal care product or pharmaceutical product using at least one delivery systems according to claim 1.

9. Premix, dietary supplement, food product, feed product, personal care product or pharmaceutical product comprising at least one delivery systems according to claim 1.

Description

EXAMPLES

Example 1

[0069] 12 g Na alginate (grinsted sodium alginate) were dissolved in 568 g water at 50 C. with stirring. 1.5 g Ca chloride dihydrate was dissolved in 148.5 g water. 80 g granulated Riboflavin (B2 Universal, DSM) was filled in a fluid-bed processor (WFP mini, DMR, Wurster configuration). All coating steps were performed at a product temperature of about 40 C. The alginate solution was sprayed on the fluidized Riboflavin granulate first. After spraying of the alginate solution, the feeding tube was briefly rinsed with water. The Ca chloride solution was sprayed on the inner coating at 40 C. for hardening. After the hardening solution, 117 g aqueous shellac preparation with a solids content of 25% (Aquagold SSB, Stroever) was sprayed as outer coating. After spraying of the shellac, the product was dried in the fluid bed. 103 g coated granules were obtained.

[0070] Composition of the final coated granulate was 60% Riboflavin, 9% alginate, 1% Ca chloride and 30% shellac.

[0071] Protection of riboflavin under stomach conditions was tested with 0.1N HCl at 37.5 C. using a USP-4 (SOTAX) apparatus. After 1 hours less than 20% of the riboflavin was released.