INTRAOCULAR SECONDARY LENS AND APPLICATION METHODS THEREOF THAT CAN BE ADHERED ON THE INTRAOCULAR LENS IN PSEUDOPHAKIC EYES

20230041330 · 2023-02-09

    Inventors

    Cpc classification

    International classification

    Abstract

    The present invention relates to an intraocular secondary lens (L) for insertion into the eye other than the lens that is implanted in the eye during cataract surgery so as to change the refractive power and/or to change the direction and shape of the image rays entering the eye in the patient who have undergone cataract surgery and to whom intraocular lenses are inserted. The secondary lens (L) is in a form that can be easily adhered on the primary lens (M) or the capsule (4) in which the primary lens is located and be easily removed from thereto, it has a foldable feature and contains adhesive nanostructures (6) thereon. It can be easily applied to the eye without need for structures such as hole, notch, foot etc. on the primary lens (M) with the invention by means of the nano structures (6) on the secondary lens. Said secondary lens (L) may be in the form of normal refractive, diffractive, accommodative, and toric, trifocal, multifocal, or combinations thereof, or optionally may carry devices with different optical properties.

    Claims

    1. An intraocular secondary lens (L) in the form that is directly implantable on the primary lens or on the capsule (4) containing the primary lens, without any deformation and without making any hole or notching on the primary lens, for use in pseudophakic eyes that have undergone cataract surgery and have had an intraocular lens (primary lens) implanted in the eye, characterized in that; it comprises adhesive nano/micro structures (6) in removable form on the lower contact surface and/or upper contact surface to adhere on the surface where it is implanted.

    2. An intraocular secondary lens (L) according to claim 1, characterized in that; it comprises nano/micro structures (6) only on the lower surface contacting the primary lens (M) or on the lower surface contacting the primary lens (M) and on the upper surface contacting the capsule (4) in case the secondary lens (L) is applied on the primary lens (M) in the capsule (4).

    3. An intraocular secondary lens (L) according to claim 1, characterized in that; it comprises nano/micro structures (6) on its lower surface only in contact with the capsule (4) in case secondary lens (L) is located on the capsule (4).

    4. An intraocular secondary lens (L) according to claim 1, characterized in that; the secondary lens (L) comprises nano/structures (6) with which adhesion to the surface it is placed is provided by using any physical adhesion that has an adhesive effect such as hydrophobic-hydrophobic bonds, Van der Waals bonds, electrostatic bonds, vacuum force etc. and that can be placed on the surface in various forms or methods.

    5. An intraocular secondary lens (L) according to claim 1, characterized in that; the secondary lens (L) is foldable.

    6. An intraocular secondary lens (L) according to claim 1, characterized in that; the secondary lens (L) is made of flexible materials.

    7. An intraocular secondary lens (L) according to claim 1, characterized in that; the secondary lens (L) is made of acrylic, silicone or hydrogel.

    8. An intraocular secondary lens (L) according to claim 1, characterized in that; the optics of the secondary lens (L) is hydrophobic or hydrophilic.

    9. An intraocular secondary lens (L) according to claim 1, characterized in that; the diameter of the secondary lens (L) is between 3-7 mm.

    10. An intraocular secondary lens (L) according to claim 1, characterized in that; the secondary lens (L) is in the form of normal refractive, diffractive, accommodative, toric, trifocal, multifocal, and/or combinations thereof.

    11. An intraocular secondary lens (L) according to claim 1, characterized in that; the secondary lens (L) comprises apparatus with different optical properties.

    12. An intraocular secondary lens (L) according to claim 1, characterized in that; nano/micro structures (6) are between 1-100 microns.

    13. An intraocular secondary lens (L) according to claim 1, characterized in that; nano/micro structures (6) are made of hydrophobic, hydrophilic or superhydrophobic processable biocompatible polymers.

    14. An intraocular secondary lens (L) according to claim 1, characterized in that; it comprises nano/micro structures (6) that can be made by any of the following methods; two-photon lithography, electron microscope lithography, electrospin method, ultraviolet inking-printing-curing, plasma abrasion, colloidal assembly and casting.

    15. An intraocular secondary lens (L) according to claim 1, characterized in that; it comprises a frame (8) bonded with nano/micro structures on the primary lens (M) or on the capsule (4) containing the primary lens wherein the secondary lens is implanted on the primary lens (M) or on the capsule (4) by means of the frame (8).

    Description

    DESCRIPTION OF THE FIGURES

    [0019] In order to understand the advantages of the present invention with its structure and additional elements, it shall be evaluated with the following defined figures.

    [0020] FIG. 1: Front view of the primary intraocular lens (A), (B) front view (C) after insertion into the capsular structure, (C) transverse view of its status in the eye after insertion into the capsule.

    [0021] FIG. 2: 360° location of adhesive nanostructures in the adhered secondary lens.

    [0022] FIG. 3: view of secondary lenses in different structures when adhered on primary lens (A, B) and capsule (C).

    [0023] FIG. 4: view of the locations of adhesive nanostructures dispersed over the secondary lens.

    [0024] FIG. 5: view of the adhesive nanostructures on the secondary lens when they are dispersed as segmented and adhered onto the primary lens.

    [0025] FIG. 6: view of the primary lens when it adheres on the capsule where it is found, by means of adhesive nanostructures placed on the feet on the secondary lens.

    [0026] FIG. 7: side view of the secondary lens when adhered on the primary lens.

    [0027] FIG. 8: view of adhesive nanostructures mounted on or produced on the secondary lens.

    [0028] FIG. 9: views of (A) Spherical, (B) Toric and (C) Multifocal secondary lenses.

    [0029] FIG. 10: Views of the secondary lens (L) implanted by the frame attached on the primary lens (M) or the capsule (4).

    DESCRIPTION OF THE REFERENCES

    [0030] The features of the invention in the figures are enumerated and the corresponding numbers are given below in order to explain the secondary lens developed with this invention better: [0031] 1. Optical plane with refraction of primary lens [0032] 2. Upper leg [0033] 3. Lower leg [0034] 4. Capsule/bag in which the primary lens is implanted [0035] 5. Front capsule border [0036] 6. Nano/micro structure [0037] 7. Foot with nanostructure [0038] 8. Frame [0039] A. Front capsule opening [0040] I. Iris [0041] K. Cornea [0042] L. Secondary lens [0043] M. Primary lens

    DETAILED DESCRIPTION OF THE INVENTION

    [0044] The present invention relates to an adhesive/removable secondary lens so as to be applied on the primary lens or the capsule (4) containing the primary lens, in patients who have undergone cataract surgery and have an intraocular lens (primary lens) implanted in their eye. This intraocular secondary lens comprises nano/micro structures (6) in adhesive form on it so as to attach to the surface where it is implanted. Said secondary lens (L) comprises nano/micro structures (6) on the lower contact surface and/or the upper contact surface so as to adhere on the surface where it is implanted.

    [0045] The secondary lens (L) may comprise nano/micro structures (6) on the lower surface only contacting the primary lens (M) or may comprise nano/micro structures (6) both on the lower surface contacting the primary lens (M) and on the upper surface contacting the capsule (4) in case that the secondary lens (L) is implanted on the primary lens (M) in the capsule (4). The secondary lens (L) comprises nano/micro structures (6) on its lower surface only in contact with the capsule (4) in case it is located on the capsule (4).

    [0046] The intraocular secondary lens (L) subjected to the invention is in foldable form and is made of different flexible materials such as acrylic, silicone or hydrogel. There are nano/micro structures (6) providing adhesion on the surface where the secondary lens (L) contacts with the primary lens (M) or on the surface where it contacts with the capsule (4) containing the primary lens. As in FIGS. 2 and 3, these can be placed on the surface by different manners or methods and they are placed on the legs extending from the secondary lens and adhered onto the capsule (FIG. 3-C).

    [0047] The diameter of the intraocular secondary lens (L) is between 3-7 mm. Therefore, it can be adhered on the lens optics (FIG. 7) only through the front capsule opening (A), also it can be adhered on capsule in the periphery.

    [0048] The optics of the intraocular secondary lens (L) can be hydrophobic or hydrophilic.

    [0049] The nanostructures in the secondary lens (L) can be originated from nature such as octopus suction cups or Tokay gecko foot holder etc. or can have different technical shapes (FIG. 8). The secondary lens (L) can adhere onto the primary lens or to the capsule tissue in which it is found by using any physical adhesion that has an adhesive effect such as hydrophobic-hydrophobic bonds, Van der Waals bonds, electrostatic bonds, vacuum force etc. and they can be adhered and removed like reusable double-sided stickers or Nano gel-like strip tapes.

    [0050] Nano/micro structures (6) have a dimension between 1 nm-100 mm by specific methods such as electron microscope lithography and can be produced with desired shape and structure on the lens and can be implanted on the secondary lens (L) after its production. More nano/microstructures (6) can be implanted on the surface of the secondary lens (L) since the nano/micro structures (6) have such dimensions, therefore the adhesion strength on the surface to which the secondary lens (L) will be adhered increases. The location and configuration of the nanostructures (6) on the secondary lens (L) can be changed as required. Also, these nano/micro structures (6) can be produced with different methods, and they can affect the passage of the rays forming the vision in a small and imperceptible manner since they are very small structures, this difference can be ignored.

    [0051] Nano/micro structures that can be produced from processable biocompatible polymers such as hydrophobic, hydrophilic or superhydrophobic siloxane, polyurethane, acrylic etc. nano/micro structures (6), can be made by nanotechnological methods such as two-photon lithography, electron microscope lithography, electrospin method, ultraviolet inking-printing-curing, plasma abrasion, colloidal assembly and casting, other casting methods etc. and different forms can be given to these nano/micro structures (6).

    [0052] Said secondary lens (L) may be in the form of normal refractive, diffractive, accommodative, toric, trifocal, multifocal, or combinations thereof, or optionally may comprise devices with different optical properties or may be produced for different cosmetic purposes (for example: iris prosthesis) (FIG. 9). Furthermore, the secondary lens (L) can be injected into the eye through small incisions by means of different injectors or can be easily removed from the eye since it is foldable.

    [0053] The optical axis of the secondary lens (L) can be adjusted easily and its location can be easily changed because it can be attached and detached. While the secondary lens (L) to be placed on the primary lens is held on the primary lens (M) by means of the nano/micro structures (6), this implantation procedure can be performed with more than one content and with more than one step. In an embodiment of the invention; the secondary lens (L) can be implanted and removed by means of a frame (8) bonded with nano/micro structures on the primary lens (M) or on the capsule (4) containing the primary lens. This frame (8) can be produced in different shapes and structures in accordance with different secondary lens (L) structures. The secondary lenses (L) with different properties can be easily implanted and removed from the frame (8) placed on the primary lens (M) or the capsule (4). The frame (8) can stay on the eye continuously, and the optical mechanism to be placed on it can be changed many times. Thus, possible trauma on the lens is minimized and multiple lens changes can be easily achieved with a single adhesion (FIG. 10).