Painting with biocides composition and/or prolonged release pesticides

Abstract

This invention refers to a paint composition with prolonged release biocides to repel, reduce, and control insects, characterized by: a) A cbp vehicle, preferably a water-based acrylic vinyl paint; b) At least one pyrethroid biocide or its mixture, selected from: b1) microencapsulated deltamethrin as an active ingredient: b2) microencapsulated cypermethrin as an active ingredient; Where said pyrethroid biocides are activated or catalyzed through (PBO) piperonyl butoxide, and Wherein said microcapsules of the active ingredients are obtained through a microencapsulation process by interfacial polymerization, and/or a microencapsulation by ionic gelation process, for a prolonged release with regards to the biocidal active ingredients' interval.

Claims

1. A paint composition with prolonged release biocides to repel, reduce, and control insects, comprising: a) a dispersing medium of a water-based acrylic vinyl paint; b) microcapsules comprising at least one pyrethroid biocide or its mixture, selected from: b1) microencapsulated deltamethrin as an active ingredient; b2) microencapsulated cypermethrin as an active ingredient; and b3) microencapsulated cypermethrin and deltamethrin as active ingredients; c) at least one pyrethroid biocide or its mixture, selected from: c1) cypermethrin slurry; and c2) deltamethrin slurry; where said at least one pyrethroid biocide is activated or catalyzed by piperonyl butoxide (PBO) and dispersed within the vinyl acrylic paint, forming a synergistic effect between the piperonyl butoxide (PBO) and the active ingredients of the microcapsules, as well as between the piperonyl butoxide (PBO) and the slurry and wherein said microcapsules of the active ingredients are obtained by a microencapsulation process through interfacial polymerization, and/or a microencapsulation process through ionic gelation, for an extended release in terms of time of biocidal active ingredients.

2. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 1, wherein said microcapsules of microencapsulated cypermethrin are comprised of: from 20% to 40% mineral oil; 10% to 15% active ingredient of the cypermethrin; from 2% to 5% propylene glycol; from 1% to 4% melamine; from 1% to 4% of chitosan; from 1% to 2% of 50% acetic acid; from 2% to 4% of 25% glutaraldehyde; from 0.1% to 0.5% of 50% sodium hydroxide; from 0.1% to 0.5% of 5% calcium chloride; and distilled water to complete a final volume of an emulsion to be encapsulated.

3. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 1 wherein said microcapsules of microencapsulated deltamethrin are comprised of: from 20% to 30% mineral oil; from 9% to 15% of active ingredient of the deltamethrin; from 15% to 20% propylene glycol; from 1% to 4% of 10 mole nonyl phenol from 1% to 4% melamine; from 1% to 4% of chitosan; from 1% to 2% of 50% acetic acid; from 2% to 4% of 25% glutaraldehyde; from 0.1% to 0.5% of 50% sodium hydroxide; from 0.1% to 0.5% of 5% calcium chloride; and distilled water to complete a final volume of an emulsion to be encapsulated.

4. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 1, wherein said microcapsules of microencapsulated of cypermethrin and deltamethrin are comprised of: from 15% to 20% mineral oil; from 10% to 11% of active ingredients of cypermethrin and deltamethrin (in a 20-20 ratio; from 4% to 9% propylene glycol; from 1% to 3% gelatin, xanthan gum, guar gum, or Arabic gum; from 1% to 3% of chitosan; from 1% to 2% of 50% acetic acid; from 2% to 4% of 25% glutaraldehyde; from 0.1% to 0.5% of 50% sodium hydroxide; from 0.1%10 0.5%% of 5% calcium chloride; distilled water to complete a final volume of an emulsion to be encapsulated.

5. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 2 wherein said microcapsules of encapsulated cypermethrin and microcapsules of deltamethrin are obtained through a microencapsulation process through interfacial polymerization.

6. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 4, wherein said microcapsules of encapsulated cypermethrin and deltamethrin are obtained through a microencapsulation process by ionic gelation.

7. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 1 comprising a) from 60% to 80% of microcapsules of the microencapsulated cypermethrin formulated by microencapsulation by interfacial polymerization; b) from 5% to 8%, of microcapsules of microencapsulated deltamethrin formulated by microencapsulation by interfacial polymerization, b) from 18% to 71.75% of microcapsules of microencapsulated cypermethrin and deltamethrin formulated by microencapsulation by ionic gelation.

8. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 7, having a slurry dispersion in 10 mole nonyl phenol.

9. The paint composition with prolonged release biocides to repel, reduce, and control insects, according to claim 7, wherein the slurry comprising: a) microcapsules of the microencapsulated cypermethrin; b) microcapsules of the microencapsulated deltamethrin; c) Mineral Oil; d) Propylene glycol; and e) 10 mole nonyl phenol.

Description

DESCRIPTION OF THE INVENTION

(1) In general, the paint composition with biocides and/or prolonged-release pesticides to repel, reduce, and control insects consists of a cbp vehicle, preferably a water-based vinyl paint mixed with at least one insecticidal active ingredient with highly effective double microencapsulation; and optionally includes a microencapsulated reflective pigment and/or a microencapsulated high luminosity photoluminant pigment, which generates a dual effect to repel and control insects.

(2) The following are the main physical-chemical properties of the insecticides to be considered when selecting the microcapsule

(3) a.—Alkalinity Resistance

(4) Alkalinity is something natural and common in almost all the materials used in the construction of houses and, with this, in the supports in which the anti-insect paint is going to be applied. This factor is of decisive importance in the application of pesticides since the great majority of active ingredients, particularly organophosphates and carbamates, decompose in alkaline media, needing pH between 5 and 6 to remain relatively stable (Table A).

(5) TABLE-US-00001 TABLE A Average life of some insecticidal active ingredients in aqueous media. Active ingredient Decomposition time (Average life) Diflubenzuron Stable in the pH range between 5 and 7. Hydrolyzes at pH 9. cypermethrin pH 9 (7 days). Stable at a pH 4. Very stable in acid solutions deltamethrin pH 7 (8 hrs.) more stable in medium acid solutions than alkaline ones D-allethrin Stable at a pH 5 after 31 days. pH 7 (500 days) pH 9 (4.3 days) Chlorpyrifos A pH 10 (7 days). It is stable in neutral and slightly acid solutions. Diazinon pH 9 (136 days). pH 7.5 (185 days). pH 5 (31 days). Malathion It hydrolyses rapidly at pH above 7. The optimum pH range is between 5 and 6. Permethrin Stable at a pH between 5 and 6. Methylperimiphos A pH 8 (5 days). pH 5 (7 days). Pyriproxyfen Stable in the pH range betiveen 4 and 9.

(6) The active ingredient microcapsule release mechanisms can be by microcapsule porosity release, thermal expansion, fracture by force, or pressure and friction.

(7) The microcapsules of the present invention maintain the active substances in a 7-9 pH range and the paint maintains an 8-9 pH which achieves an ideal medium for its application and preservation, allowing to have a stability for an adequate time, a half-life that does not harm the painting effectiveness interval

(8) b. Adherence.

(9) Normally, outdoor paints have adhesion on substrates such as concrete, cement, and the rest of the mineral components that are usually found in a façade or work wall; but sometimes there are other types of materials where this type of paint adherence is not satisfactory. A paint is of high adhesion and the microcapsules of the present invention do not interfere at all in this feature.

(10) c. Outdoors Resistance.

(11) This properly is intended to measure the ability of formulations to maintain their properties against all types of external abiotic agents, moisture, solar radiation, heat, pressure, and even biotic agents such as microorganisms, fungi, and other living beings.

(12) In the case of the paintings, all suffer a deterioration—to a greater or lesser degree—when exposed to the inclement weather. The most common effects are yellowing, cracking, and can also heat up (they give off surface dust). To measure their resistance to inclement weather exposed to an “accelerated aging”, subjecting the sample to a UV radiation more intense than normal, as well as, to varying conditions of humidity and heat.

(13) d. Heat Resistance

(14) This property is especially important in insecticides and/or pesticides that have active ingredients of the pyrethroid family, since they degrade very rapidly at high heats. By the formulation of our additive with microcapsules, this has a greater resistance to heat than conventional insecticides individually

(15) e. Wet Rub Resistance

(16) This property, complementary to water resistance, indicates the degree of washability that a coating has. It is also a way to measure the paint resistance in case of very intense rains.

(17) Studies and investigations of the existing insecticides were carried out in order to determine which are suitable for interaction with human beings, domestic animals, farm animals, but, above all, which had the function of repelling and eliminating flying and crawling insects. Thanks to this, the optimal components for this development were determined and selected.

(18) On the other hand, options were analyzed to increase the useful life of the product, as well as its effectiveness from the double microencapsulation process; vital process in the product increasing its useful his and action for more than 24 months.

(19) Next, some insecticides are described in a more non-limiting manner which can be used in the formulation.

(20) TABLE-US-00002 Insecticides Type of Active Presen- Nomenclature product ingredient Toxicity tation Coumaphos Insecticide Coumaphos Toxic Powder Triclorphon Insecticide Metrifonate Moderately toxic Powder Boric acid Insecticide Hydrogen Group II powder borate Moderately toxic dimethyl Insecticide Carbomate Group II Liquid carbomate Moderately toxic Carbofuran Insecticide Carbomate Group II Liquid moderately toxic Alfa Insecticide Cypermethrin Group II powder Cipermethrin Moderately toxic

(21) The paint composition with prolonged release biocides to repel, reduce, and control insects, in preferred embodiment consists of: a) A cbp vehicle, preferably a water-based acrylic vinyl paint; b) At least one pyrethroid biocide or its mixture, selected from: b1) microencapsulated deltamethrin as an active ingredient; b2) microencapsulated cypermethrin as an active ingredient;

(22) Where said pyrethroid biocides are activated or catalyzed by (PBO) piperonyl butoxide.

(23) Alternatively, and optionally as an addition to the paint composition with biocides and/or extended release pesticides to repel, reduce, and control insects, includes at least one of, or the mixture of: c) a microencapsulated photoluminescent pigment, d) a microencapsulated reflecting pigment.

(24) In the case of the composition that includes at least one of, or the mixture of, a microencapsulated photoluminescent pigment and a microencapsulated reflecting pigment, it generates a dual effect providing a strong attraction of insects when the product is applied on any surface, due to the luminosity as a result of the mixture of the described components, works with a high effectiveness and efficiency both during the day and at night thanks to the high luminosity pigments that mainly have the property of glowing in the dark when charging light energy and/or thermal by any source, whether natural or artificial; that is, with the effect of attracting lucifugus insects with positive phototaxis working 24 hours in comparison to 8 hours of traditional products.

(25) Some of the insects attracted by the light component of the present invention composition are moths, flies, mosquitoes, and many other lucifugus insects that have positive phototaxis, meaning they are naturally attracted to it.

(26) Other insects such as cockroaches, insect larvae have negative phototaxis, which means that they will not be attracted by the composition's luminosity but will be repelled or killed by it given the insecticidal composition.

(27) In the preferred invention modality, the biocides microcapsules of the paint composition with prolonged release biocides to repel, reduce, and control insects is made through a microencapsulation process by interfacial polymerization, and a microencapsulation process by ionic gelation for a prolonged release with regards to the biocidal active ingredients' interval.

(28) The microencapsulation comprises a quite heterogeneous set of procedures and employs very diverse techniques and materials within which three stages can be considered to obtain it, the most important to follow for their manufacture are: Nucleus Coating material Characterization

(29) The nucleus is comprised of substances of a liquid nature (mineral oil) in which the active ingredients are incorporated, which can be liquids of (preferably) or emulsified or dispersed solids in a suitable vehicle or related to the polymer liquid.

(30) In the nucleation process, the core material is constituted by solid particles or small drops of liquid and their integration carried out through agitation using adjuvants, stabilizers, antioxidants, and diluents.

(31) The coating materials used must be common between the core and shell since its hydrophilic or hydrophobic nature can cause repulsion of charges and therefore a destabilization of the particle, as a result, the reaction would return and there would be no polymer.

(32) In the characterization, the core material is given under certain conditions that promote their release, these conditions are independent of moisture and pH, as well as, the pressure and mechanical force acting on them.

(33) Variable Identification

(34) The following is considered in the microcapsule release process: 1.—Minimum percentage concentration 2.—Concentration of active ingredient to be released 3.—pH of the medium 4.—Type of paint to use 5.—Heat to apply 6.—Environmental heat 7.—Surface roughness to paint 8.—Insects to eliminate 9.—Endemic insects 10.—Invading insects 11.—Pests 12.—Film thickness
Micro Encapsulation Processes Used a) microencapsulation process by interfacial polymerization, and b) microencapsulation process by ionic gelation

(35) Microcapsules are obtained with the use of these two microencapsulation processes, which offer the advantage of encapsulating the active ingredient and achieving its release in a gradual manner and in stages, allowing handling of several mixtures to achieve this. a) Microencapsulation by interfacial polymerization—In this process, a polymer of a monomer is produced at the interface of two immiscible substances, which gives rise to the formation of a membrane that will later be a precursor of the microcapsule wall. In this form of reaction, the following phenomena are followed: 1. Dispersing the aqueous solution of a water-soluble material in an organic phase to produce a stable w/o emulsion. 2. Formation of a polymeric membrane on the surface of water droplets that is initiated by the addition of a soluble or dispersible complex in the oil of the previous emulsion. 3. Separation of the microcapsules of the organic phase and its transfer to another container to remove the water, the separation of the final microcapsules is done through centrifugation. b) For the gelation process there is an ion exchange of the electric double layer that is formed between the nuclei of the bonding atoms, soluble calcium salt is added to the field of a previously stirred emulsion. The particle size cannot be controlled if the agitator does not have the correct speed.

(36) In external gelation, the soluble calcium salt is added in an A/O emulsion. The particle size cannot be well controlled, and particles tend to coagulate in large masses before acquiring the proper consistency. Also, the particle size that is obtained is big.

(37) In this variety of process, the microcapsule has a relatively simple morphological structure. It is composed of two clearly differentiated elements, the active core and a thin polymeric framework (shell) that surrounds the first one, by the properties of the polymer, a gradual release of these active ingredients is achieved, inserted according to the specific requirements of application of the substrate in which the microcapsules are deposited.

(38) The core is composed of substances of a liquid nature (mineral oil) in which insecticidal active ingredients are incorporated.

(39) The formation of the microcapsule is a complex chemical-physical process with which a suspension of microcapsules ranging between one and several hundred micrometers is obtained. The progressive and controlled release of the microencapsulated active ingredients is achieved thanks to the fact that the nature of the coating polymer allows it.

(40) The fundamental element of the formulation of the additive is the insecticidal and/or biocidal polymeric microcapsule. Optionally and alternatively it can also contain other components such as a photoluminescent pigment of high luminosity whose main charge is calcium carbonate. The polymer is a vinyl and insecticides vary depending on the type of vector, place of application, strategy to follow for the control of the pest and the different regulations.

(41) In any case, they are always insecticidal and acaricidal active ingredients with a broad spectrum of action and frequently used in many insecticide formulations. Thus, pyrethroids are used when you want to perform an immediate control and achieve a great shock effect without requiring a high residuality. Organophosphates are used in the case that it is intended to obtain a prolonged effectiveness against a more immediate effect. In all cases, the paint incorporates a crawler/cockroach repellent insecticide.

(42) Microcapsule Chemical Development A polymer is a chemical substance composed of macromolecules, usually organic, that have been formed by the union of smaller repeating molecules called monomers.

(43) Thus, achieving a formulation with a gradual release and at the same time effective will depend, to a large extent, on the proportions in which these monomers are included to form the resulting polymer, though also on other factors inherent to the manufacturing process such as the moment of incorporation of the insecticide active ingredients and the temperatures reached.

(44) For the different stages of life, for example, of a paint (manufacture—liquid paint) (liquid/dry paint application) (retention—dry paint) of different types of polymer. First, the manufacturing stage in which the polymer is dispersed in water which makes the hardness of the shell be low, when applied and drying begins, its hardness increases, in the case of the hard polymer, the microcapsule would be so rigid that it would not allow an easy release of the active ingredient. On the contrary, in the case of the soft polymer, the release would be so fast that the persistence of the efficiency would be too low. In the case of the polymer of the present invention, the appropriate hardness and flexibility balance is obtained, achieving a high persistence of the effectiveness by controlled release of active ingredients.

(45) Other equally important steps are the addition of fillers and pigments and the active ingredients insecticides and/for pesticides (biocides), and stabilizers, required to form the insecticidal polymer microcapsule that protects the assets in an acidic medium (pH 4-5) to maintain the chemical stability of the same over time and, with it, all their insecticidal properties.

(46) A double shell can be granted to an active ingredient giving it a longer life in its release so that this feature could be controlled over time.

EXAMPLE 1

(47) Cypermethrin microcapsules formulated by microencapsulation through interfacial polymerization of Cypermethrin (active ingredient, biocide).

(48) In the interfacial polymerization, melamine with chitosan and an active agent with the encaser which glutaraldehyde is used and sealed with calcium chloride.

(49) Components

(50) from 20% to 40% mineral oil; 10% to 15% active ingredient (biocide) Cypermethrin; from 2% to 5% propylene glycol 2% to 5% Piperonyl Perbutoxide (PBO) from 1% to 4% of a 15% NF-10 solution from 1% to 4% Melamine from 1% to 4% of Chitosan from 1% to 2% of 50% acetic acid from 2% to 4% of 25% glutaraldehyde from 0.1% to 0.5% of 50% sodium hydroxide from 0.1% to 0.5%% of 5% calcium chloride distilled water as a cbp vehicle

EXAMPLE 2

(51) Deltamethrin microcapsules formulated by microencapsulation through interfacial polymerization of Deltamethrin (active ingredient, biocide).

(52) In the interfacial polymerization, melamine with chitosan and an active agent with the encaser which glutaraldehyde is used and sealed with calcium chloride.

(53) Components

(54) from 20% to 30% mineral oil; from 9% to 15% of active ingredient (biocide) Deltamethrin; from 15% to 20% propylene glycol 2% to 5% Piperonyl Perbutoxide (PBO) from 1% to 4% of a 15% NF-10 solution from 1% to 4% Melamine from 1% to 4% of Chitosan from 1% to 2% of 50% acetic acid from 2% to 4% of 25% glutaraldehyde from 0.1% to 0.5% of 50% sodium hydroxide from 0.1% to 0.5%% of 5% calcium chloride distilled water as a cbp vehicle
Methodology 1.—Weigh melamine and the active ingredient (biocide with mineral oil) (Cypermethrin or Deltamethrin) together with the propylene glycol; 2.—Melamine, the active ingredient (Cypermethrin or Deltamethrin) with mineral oil and propylene glycol are homogeneously incorporated in a reactor for 30 minutes and chitosan previously dispersed in a solution with 50% acetic acid is added; 3.—Stir vigorously until a paste is formed and add a 50% sodium hydroxide solution, piperonyl perbutoxide, 15% NF-10 solution, and a bit of 25% glutaraldehyde; 4.—Stir for 30 minutes and add the remaining 25% glutaraldehyde followed by 5% calcium chloride; 5.—Stir the resulting mixture for 40 minutes and arrange for filtration or, if necessary, decant. The filter paper is washed 3 times with distilled water and the formed product is saved; 6.—Centrifuge and air dry under pressure. 7.—For convenience, use the material dispersed in aqueous solution (slurry) in the form of wet powder 8.—Pack and store in sealed containers and avoiding light)
Microencapsulation Process by Ionic Gelation

(55) In the ionic gelation, gelatin, Guar gum, Xanthan gum, or Arabic gum, and chitosan are used in addition to the active ingredients using an encapsulating agent which is glutaraldehyde and sealed with calcium chloride.

EXAMPLE 3

(56) Cypermethrin-Deltamethrin microcapsules formulated by Microencapsulation through ionic gelation.

(57) Components

(58) from 15% to 20% mineral oil; from 10% to 11% of active ingredient (biocide) Cypermethrin-Deltamethrin (in a 20-20 ratio); from 4% to 9% propylene glycol 2% to 5% Piperonyl Perbutoxide (PBO) from 1% to 4% of a 15% NF-10 solution from 1% to 3% of Gelatin, Guar gum, Xanthan gum, or Arabic gum from 1% to 3% of Chitosan from 1% to 2% of 50% acetic acid from 2% to 4% of 25% glutaraldehyde from 0.1% to 0.5% of 50% sodium hydroxide from 0.1% to 0.5%% of 5% calcium chloride distilled water as a cbp vehicle

(59) In the preferred modality of the invention, the following is used for the formulation of one liter of paint: a) Water based vinyl-acrylic paint as vehicle b) from 60% to 80%, preferably 71.75% of Cypenethrin microcapsules formulated by Microencapsulation by interfacial polymerization; c) from 5% to 8%, preferably 6.73% of Deltamethrin microcapsules formulated by Microencapsulation by interfacial polymerization, b) from 18% to 71.75% of Cypermethrin-Deltamethrin microcapsules formulated by Microencapsulation by interfacial polymerization;

(60) In the paint formulation, the microcapsules of the stabilized and emulsified active agents are mixed together with the paint and direct homogenization for immediate use.

(61) The mixture is made at an agitation speed of 8,000-25,000 rpm obtaining an average viscosity of 950,000 cps and left in constant agitation for 1-5 hrs. to obtain an average viscosity of at least 250,000 cps and stirring another interval of 1.5 hr. to obtain a viscosity of 200,000 cps.

(62) In another of the modalities of the paint formulated as described, slurry is incorporated for an immediate effect in the painting.

(63) The following components are used in the Slurry formulation: a) Cypermethrin 14.21% b) Deltamethrin 4.74% c) Mineral Oil 46.55% d) Propylene glycol 22.98% e) NF-10 at 20%, 11.52%

(64) For its production it is required a specialized high purity stainless steel equipment, it must also be a high speed mixer in stainless steel, and fastened with sealed doors with adjusted grubs to avoid mixture volatility, with speed regulator since at very high speeds, you can break the microcapsule and/or generate a lot of heat inside and this can cause the microcapsule to break and the desired effects decrease or disappear.

(65) This innovation is aimed at controlling and reducing diseases transmitted by insects inability to vulnerable classes, since this additive has low costs and is compatible with 90% of the formulas of paints, regardless of price or brand.

(66) The formulation according to the present invention contains several very important, competitive, and differentiating advantages from the technical and process point of view (double microencapsulation, original formula, and combination with independent biocide elements) as well as, from the practical point of view since said formulation presents a better performance for insect control due to its useful life that exceeds 24 months, as well as, its activated effect. On the other hand, our product can release different active ingredients in different time periods, which does not allow insects to generate immunity to said biocides and/or pesticides over time. Optionally and/or alternatively, luminescent and reflective pigments can be added to the product formulation in such a way that the paint manages to attract lucid insects with positive phototaxis and repel those with negative phototaxis. Finally, from the economic point of view our product has a lower cost compared to existing products and above all, can be used on any surface that, but not limited to, we mention below: substrates such as textiles, paper, plastics, wood, metals, stones, concretes, plasters, and any construction element and interior design. The social benefits are wide since our invention will be a very important player in the control of pests and diseases transmitted by insects.

(67) An important part of the double encapsulation is that through this system we incorporate the use of different microencapsulated insecticide elements that will be released in different intervals (two or more depending on the number of families of insecticides added to the formula). The release programming is controlled from the specific characteristics of the microcapsule used during the manufacturing process (shell size and hardness). The benefits of this system allow elimination resistance that insects develop over time to certain insecticides, since release programming of different families of insecticides over time, reduces the natural evolution of insects to generate resistance and therefore, allows effective pest control.

(68) The combination of microencapsulation methods and use of other materials, as well as the microencapsulation process, make it possible to obtain a product that, due to its nature, has a longer duration compared to environmental factors such as heat, pressure, pH, among others. On the other hand, the product, thanks to the different microencapsulation techniques used, as well as alternative slurry inclusion (optional), allows a release of active ingredients (pyrethroids) in different time intervals. Initially, slurry actively releases the pyrethroids (biocides), subsequently the microcapsules manufactured from the ionic gelation and by interfacial polymerization; the above due to the nature of the shell of each of the products.

(69) On the other hand, this invention through the use of different microencapsulation disciplines allows a greater product effectiveness from the prolonged release of active ingredients at different time intervals because as is well known, insects generate defenses and/or immunity to certain active ingredients to which they are exposed to and it is from this invention that said insects receive different combinations of active ingredients (pyrethroids) over time, reducing their immunity and significantly increasing the effectiveness of the product.

(70) The combination of two microencapsulation techniques allows the release of active agents in three different stages consisting of: 1.—Initial release in a period from 6 months to a year, also observing that it works from 1 to 9 months with an optimum effectiveness achieved by the release of formula components 2. —Average release for a period of 1 to 2 years due to changes in environmental heat, atmospheric pressure, or increased environment humidity, and works in good conditions in a period of 1 to 2.5 years. 3.—Slow or final release for a period of 1 to 3 years due to environmental humidity effects, microcapsules fracture due to mechanical effects, and observation of slow release in a final period of 1 to 4 years of effectiveness, already low but still acceptable.

(71) Improves product effectiveness from prolonged release of active ingredients at different time intervals since, as is well known, insects generate defenses and/or immunity to certain active ingredients to which they are exposed and is as of this invention that said insects receive different combinations of active ingredients (pyrethroids) over time, reducing their immunity, and significantly increasing product effectiveness.

(72) The invention has been sufficiently described so that a person with average skills in this matter can reproduce and obtain the results that we mentioned in the present invention.

(73) However, any skilled person who is competent in the present invention may be able to make modifications not described in the present application, however, if for the application of these modifications in a certain structure or in the manufacturing process of the same, it is required of said matter in the following claims, said structures should be included within the scope of the invention.