Cover removal system for use in controlled environment enclosures
10781091 ยท 2020-09-22
Assignee
Inventors
- Christopher Procyshyn (Surrey, CA)
- Ross M. Gold (North Vancouver, CA)
- Steve Sang Joon Park (Oakville, CA)
- Jeroen Immerzeel (Squamish, CA)
- Paul NOWAKCZYK (Welland, CA)
Cpc classification
B65B55/027
PERFORMING OPERATIONS; TRANSPORTING
B25J11/00
PERFORMING OPERATIONS; TRANSPORTING
B67B7/14
PERFORMING OPERATIONS; TRANSPORTING
B25J21/00
PERFORMING OPERATIONS; TRANSPORTING
G01N2035/0405
PHYSICS
B65B69/00
PERFORMING OPERATIONS; TRANSPORTING
G01N2035/00277
PHYSICS
B65B57/02
PERFORMING OPERATIONS; TRANSPORTING
International classification
B67B7/14
PERFORMING OPERATIONS; TRANSPORTING
B65B57/02
PERFORMING OPERATIONS; TRANSPORTING
G01N35/00
PHYSICS
B65B69/00
PERFORMING OPERATIONS; TRANSPORTING
B25J11/00
PERFORMING OPERATIONS; TRANSPORTING
B25J21/00
PERFORMING OPERATIONS; TRANSPORTING
B65B55/02
PERFORMING OPERATIONS; TRANSPORTING
Abstract
An apparatus and method are presented for removing container covers within a controlled environment enclosure without using gloves. The apparatus comprises an articulated arm apparatus and a gripping apparatus and can further comprise a controller. The articulated arm apparatus can be configurable for holding and moving a container in three dimensions; and the gripping apparatus can be configured for gripping a container cover sealing the container. The method comprises moving the container using the articulated arm apparatus while holding a gripping area of the container cover substantially stationary using the gripping apparatus. The apparatus can further comprise a sensor configured for supplying information to the controller for determining the location of the container cover gripping area and an orientation of the container cover. The method can further comprise inspecting the container cover using the sensor. The container can be moved along a path and within a space determined by the controller.
Claims
1. An apparatus comprising a controlled environment enclosure having an aseptic interior; within the controlled environment enclosure an articulated arm apparatus and a separate rotary gripping apparatus; wherein the articulated arm apparatus is configurable for holding and moving a container in three dimensions; and the rotary gripping apparatus is configured for gripping in a substantially stationary position a gripping area of a container cover sealing the container when the articulated arm apparatus is moving the container.
2. The apparatus of claim 1, wherein: the articulated arm apparatus is configurable for holding and moving a container in three dimensions; the rotary gripping apparatus is configured for gripping a gripping area of a container cover sealing the container.
3. The apparatus of claim 2, wherein: the rotary gripping apparatus comprises two gripping elements having facing mutually engagable surfaces, at least one of the two gripping elements being rotatable about a common axis with the other of the two gripping elements to grip the gripping area of the container cover between the two facing mutually engagable surfaces; and the articulated arm apparatus comprises at least two arm segments, at least one arm segment being configurable to hold the container.
4. The apparatus of claim 2, wherein the articulated arm apparatus and the rotary gripping apparatus can be separated by a distance large enough for the gripping apparatus to not interfere with the working of the articulated arm apparatus.
5. The apparatus of claim 2, further comprising a controller for controlling at least the articulated arm apparatus and the gripping apparatus.
6. The apparatus of claim 5, wherein the moving the container is moving the container along a path that is determined by the controller and the moving the container is contained within a space determined by the controller.
7. The apparatus of claim 5, further comprising a sensor configured for supplying information to the controller for determining at least one of a location of the container cover gripping area and an orientation of the container cover.
8. The apparatus of claim 2, wherein the articulated arm apparatus is at least one of automatically controlled and reprogrammable.
9. The apparatus of claim 2, wherein the gripping apparatus is at least one of automatically controlled and reprogrammable.
10. An apparatus for peeling a cover from a pharmaceutical tub sealed with the cover, the apparatus comprising: a controlled environment enclosure configured for maintaining within an interior of the enclosure an aseptic condition and an air pressure different from an air pressure exterior to the enclosure; a mechanical gripper positioned within the controlled environment enclosure, the gripper having mutually facing upper and lower arms, the arms disposed and configured for gripping and holding substantially stationary a gripping area of the cover by mutually engaging the cover between grip surfaces of the arms when the arms are mutually engaged; and an automated mechanical holder positioned within the controlled environment enclosure, disposed and configured for engaging the pharmaceutical tub and for moving the tub to peel the cover from the tub while the gripper holds the gripping area of the cover substantially stationary.
11. The apparatus of claim 10 further comprising an air filter in fluid communication with an interior of the controlled environment enclosure, the filter configured for providing within the interior of the enclosure air filtered through the filter.
12. The apparatus of claim 10 further comprising a controller for controlling at least the automated mechanical holder and the gripper.
13. The apparatus of claim 12, wherein the controller determines a path for movement of the pharmaceutical tub and the controller determines the movement of the pharmaceutical tub to be contained within a space.
14. The apparatus of claim 12, further comprising a sensor configured for supplying information to the controller for determining at least one of a location of the pharmaceutical tub cover gripping area and an orientation of the pharmaceutical tub cover.
15. The apparatus of claim 10, wherein the automated mechanical holder is at least one of automatically controlled and reprogrammable.
16. The apparatus of claim 10, wherein the gripper is at least one of automatically controlled and reprogrammable.
17. The method of claim 10 wherein the controlled environment enclosure is configured for maintaining with an interior of the enclosure and air pressure different from an air pressure exterior to the enclosure.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1) In the drawings, which are not necessarily drawn to scale, like numerals may describe similar components in different views. Like numerals having different letter suffixes may represent different instances of similar components. The drawings illustrate generally, by way of example, but not by way of limitation, various embodiments discussed in the present document.
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DETAILED DESCRIPTION
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(18) The apparatus 100 can further comprise of a sensor 160 for sensing the container 114.
(19) The controlled environment enclosure 120 can comprise windows 121, an inlet filter 130, an inlet valve 131, a blower 132, an outlet filter 133 and an outlet valve 134. The characteristics of blower 132, inlet filter 130, and outlet filter 133 are chosen to yield a controlled environment inside controlled environment enclosure 120. The contents of the controlled environment enclosure 120 can be protected by airflow while having one or more openings (not shown).
(20) In another embodiment the controlled environment enclosure 120 can be fully sealed and be operated at a positive or negative pressure differential relative to the surroundings. Those skilled in the art will understand that several other filter and blower arrangements can be used to establish a controlled environment inside controlled environment enclosure 120. A suitable controlled environment can be obtained, for example without limitation, by means of any one or more of turbulent airflow, horizontal unidirectional airflow and vertical unidirectional airflow.
(21) The operation of the gripping apparatus 113 and the articulated arm apparatus 115 is controlled by a means located outside of environment enclosure 120. In some embodiments the means of controlling apparatus 113, apparatus 115 and enclosure 120 require a local or remote operator input device such as joy stick control, push button control, emergency stop, touch screen human machine interface, keyboard, mouse, handheld device or the like. Typically one or more of such input devices are connected to a controller 140. In
(22) The controller 140 provides control instructions to apparatus 100 over control line 150. Control line 140 is a schematic representation of all of the required mechanical linkages, electrical wiring, pneumatic, hydraulic and wireless connections to operate apparatus 100.
(23) The container 114 can be manipulated inside the controlled environment enclosure 120 by mechanical means, for example, an articulated arm apparatus 115. Suitable robotic arm manipulation systems for mechanically manipulating the container 114 include, but are not limited to, 6-axis robotic arms, Selective Compliant Articulated Robot Arm (SCARA) systems, r-theta robots, and assemblies of linear actuators and rotary actuators, or combinations thereof.
(24) In one embodiment of the apparatus 100 the articulated arm apparatus 115 can be the articulated arm apparatus described in U.S. Provisional Patent application 61/596,698, which is incorporated herein by reference.
(25) The controlled environment enclosure 120, in some examples, includes a sensor 160 for sensing the container 114 and a container cover 116 for the container 114. In the example shown in
(26) In other embodiments of this invention the controlled environment chamber 120 contains articulated arm apparatus 115 plus at least one further articulated arm apparatus (not shown in the interest of clarity). The additional at least one further articulated arm apparatus can be used, for example, for activities that can follow removal of the container cover 116 from the container 114. Apparatus 100 can be used for functions preceding the function of the filling system described in U.S. patent application Ser. No. 12/393,183, which is incorporated herein by reference.
(27) In yet another embodiment gripping apparatus 113 is added to a filling system as described in U.S. patent application Ser. No. 61/033,682, with element 30 of U.S. patent application Ser. No. 61/033,682 as the equivalent of articulated arm apparatus 115 of the present specification, chamber 20 of U.S. patent application Ser. No. 61/033,682 as the equivalent of controlled environment enclosure 120 of the present specification, and optical sensor 12 of U.S. patent application Ser. No. 61/033,682 as the equivalent of sensor 160 of the present specification. U.S. patent application Ser. No. 61/033,682 is hereby incorporated by reference.
(28) The articulation of arm apparatus 115 can be remoted operated by the operator. In another embodiment the articulated arm apparatus 115 can be an automatically controlled articulated arm. In yet another embodiment the articulated arm apparatus can be a reprogrammable automatically controlled articulated arm.
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(31) The container cover 116 can extend outside the outline of the top lip 302 of the tub 114 in at least one location, and typically extends outside the outline of the top lip 302 in a plurality of locations. The at least one area of container cover 116 that extends outside the outline of the top lip 302 provides a gripping area 301 that can be used as access for clamping. Clamping on the gripping area 301 can be complicated by the flexibility of the material of the container cover 116. The gripping area 301 can be level, bent upwards, or bent downwards.
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(33) In one embodiment of the gripping apparatus 113 the lower arm 404 is stationary and upper arm 406 is rotatable about a cylindrical axis of main shaft 403. In another embodiment of the gripping apparatus 113 the upper arm 406 is stationary and lower arm 404 is rotatable about the cylindrical axis of main shaft 403. In yet a further embodiment both upper arm 406 and lower arm 404 are rotatable about the cylindrical axis of main shaft 403.
(34) The gripping apparatus 113 can be remotely operated by the operator. In another embodiment the gripping apparatus 113 can be automatically controlled. In yet another embodiment the gripping apparatus 113 can be a reprogrammable automatically controlled gripping apparatus.
(35) We now describe at the hand of
(36) In one example embodiment, shown in
(37) The cover gripping sequence can be initiated by rotating [520] the upper arm 406 and the lower arm 404 of the gripping apparatus 113 with respect to each other by an angle that separates the mutually facing grip surfaces 407 and 408 located on respectively lower arm 404 and upper arm 406 by at least the width of the container 114. This can be done by rotating one or both of the arms 406 and 404.
(38) The method further comprises manipulating [530] articulated arm apparatus 115 to move the container 114 along the trajectory that places the gripping area 301 above the grip surface 407 of the lower arm 404. This has the result of moving [532] the container 114 towards the lower arm 404 in a trajectory that results in a bottom surface of the top lip 302 of container 114 nearing or contacting the grip surface 407 of the lower arm 404. At least during the last section of the approach, the container 114 can be moved to cause the bottom surface of the top lip 302 to substantially slide along the grip surface 407 of the lower arm 404. During this section of the approach, the tip of the lower arm 404 can be bending [534] the gripping area 301 upward in the case where gripping area 301 happens to be orientated downward to below the top lip 302.
(39) The method further comprises rotating [540] upper arm 406 to grip the gripping area 301. This comprises moving [542] the tip of upper arm 406 comprising the surface 408 over the container cover 116 during its travel to the gripping area 301. As the upper arm 406 approaches the gripping area 301, it can slide over the container cover 116 above the top surface of top lip 302. During this action, the tip of the upper arm 406 can be bending [544] down to a substantially horizontal orientation any upward bent parts of cover 116, including specifically the gripping area 301.
(40) In another example embodiment of the method, shown in
(41) The cover gripping sequence can, as above, be initiated with the rotating [550] of the upper arm 406 and the lower arm 404 of the gripping apparatus 113 with respect to each other by an angle that separates the mutually facing grip surfaces 407 and 408 located on respectively lower arm 404 and upper arm 406 by at least the width of the container 114.
(42) The method further comprises manipulating [560] articulated arm apparatus 115 to move the container 114 along the trajectory that places the gripping area 301 below the grip surface 408 of the upper arm 406. This has the result of moving [562] the container 114 towards the upper arm 406 in a trajectory that results in a top surface of the top lip 302 of container 114, covered by cover 116, nearing or contacting the grip surface 408 of the upper arm 406. At least during the last section of the approach, the container 114 can be moved to cause the top surface of the top lip 302, covered by cover 116, to substantially slide along the surface 408 of the upper arm 406. During this section of the approach, the tip of the upper arm 406 can be bending [564] the gripping area 301 downward in the case where gripping area 301 happens to be orientated upward to above the top lip 302.
(43) The method further comprises rotating [570] the lower arm 404 to grip the gripping area 301. This comprises moving [572] the tip of lower arm 404 comprising the grip surface 407 under the bottom surface of top lip 302 during its travel to the gripping area 301. As the lower arm 404 approaches the gripping area 301, it can slide along the bottom surface of top lip 302. During this action, the tip of the lower arm 404 can be bending [574] up to a substantially horizontal orientation any downward bent parts of cover 116, including specifically the gripping area 301.
(44) The gripping apparatus 113 works for a wide range of thickness of the container cover 116 by clamping the gripping area 301 of container cover 116 in between the mutually facing grip surfaces 407 and 408 located on respectively the lower arm 404 and the upper arm 406.
(45) The method provides for removing [580] the container cover 116 in the controlled environment enclosure 420. This is shown in expanded form in
(46) Referring to the articulated arm apparatus 115 and the gripping apparatus 113 as shown in
(47) In another embodiment the container cover 116 can be removed by a more general direction of motion of container 114 by manipulating [584] articulated arm apparatus 115 while the gripping apparatus 113 is holding the gripping area 301 substantially stationary. In this embodiment the articulated arm apparatus 115 is not limited to being rotated. This motion of the container 114 can be executed in a fashion and direction such as to remove the container cover 116 simultaneously along two edges of the container 114, starting from the gripping area 301.
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(49) The sensor 160 can be used for verifying the completeness of removal of the container cover 116. If, for some undetermined reason, the gripping apparatus 113 were to lose its grip on the container cover 116 during the removal of the container cover 116, the articulated arm apparatus 115 can continue moving the container 114 with the partially removed container cover 116. In the event of such partial removal of container cover 116; the previously described process of orienting substantially horizontally any up-or downward bent areas of the cover 116, including the gripping area 301, can be repeated after the articulated arm apparatus 115 repositions the gripping area 301 near the tip of the lower arm 404. If the gripping area 301 were to be no longer available, for example if the gripping area 301 were torn off, the process of gripping the gripping area 301 can be repeated after redirecting the articulated arm apparatus 115 to another suitable available gripping area 301.
(50) For the sake of clearly differentiating between the different manipulations that are undertaken by the articulated arm apparatus 120, we refer to the manipulating [584] of the articulated arm apparatus 120 to remove the cover 116 as a first manipulation, and the manipulating [530] and [560] of the articulated arm apparatus 120 to position the container 114 between the lower arm 402 and the upper arm 406 as a second manipulating, while we refer to the manipulating [582] of the articulated arm apparatus 120 to lower the container 114 or to rotate the container 114 about an axis substantially in the plane of the cover 116 as a third manipulating. The gripping apparatus 113 is not limited to the example shown in
(51) Additional Notes
(52) The drawings and the associated descriptions are provided to illustrate embodiments of the invention and not to limit the scope of the invention. Reference in the specification to one embodiment or an embodiment is intended to indicate that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least an embodiment of the invention. The appearances of the phrase in one embodiment or an embodiment in various places in the specification are not necessarily all referring to the same embodiment.
(53) As used in this disclosure, except where the context requires otherwise, the term comprise and variations of the term, such as comprising, comprises and comprised are not intended to exclude other additives, components, integers or steps.
(54) In the foregoing specification, the invention has been described with reference to specific embodiments thereof. It will, however, be evident that various modifications and changes may be made thereto without departing from the broader spirit and scope of the invention. The specification and drawing are, accordingly, to be regarded in an illustrative rather than a restrictive sense. It should be appreciated that the present invention should not be construed as limited by such embodiments.
(55) From the foregoing description it will be apparent that the present invention has a number of advantages, some of which have been described herein, and others of which are inherent in the embodiments of the invention described or claimed herein. Also, it will be understood that modifications can be made to the device, apparatus and method described herein without departing from the teachings of subject matter described herein. As such, the invention is not to be limited to the described embodiments except as required by the appended claims.
PARTS LIST
(56) 100 apparatus
(57) 113 gripping apparatus
(58) 114 container
(59) 115 articulated arm apparatus
(60) 116 container cover
(61) 120 controlled environment enclosure
(62) 140 controller
(63) 150 control line
(64) 160 sensor
(65) 121 window
(66) 130 inlet filter
(67) 131 inlet valve
(68) 132 blower
(69) 133 outlet filter
(70) 134 outlet valve
(71) 201 step
(72) 301 gripping area
(73) 302 top lip
(74) 401 base flange
(75) 402 radial seal
(76) 403 main shaft
(77) 404 lower arm
(78) 405 radial seal
(79) 406 upper arm
(80) 407 grip surface
(81) 408 grip surface
(82) [210] sensing the orientation of the gripping area
(83) [512] communicating the sensed orientation to
(84) [514] determining a trajectory
(85) [520] rotating the upper arm and the lower arm with respect to each other
(86) [530] manipulating the articulated arm apparatus
(87) [532] moving the container toward the lower arm
(88) [534] bending up the gripping area
(89) [540] rotating the upper arm to grip the gripping area
(90) [542] moving the tip of the upper arm over the container cover
(91) [544] bending down bent parts of the cover including the gripping area
(92) [550] rotating the upper arm
(93) [560] manipulating the articulated arm apparatus
(94) [562] moving the container toward the upper arm
(95) [564] bending down the gripping area
(96) [570] rotating the lower arm to grip the gripping area
(97) [572] moving the tip of lower arm under the bottom surface of the container top lip
(98) [574] bending up bent parts of the cover including the gripping area
(99) [580] removing the container cover
(100) [582] manipulating the articulated arm apparatus to establish clearance for arms
(101) [584] moving the container in a substantially diagonal trajectory