Solubilizer for cosmetic preparations

Abstract

The present invention relates to a mixture comprising (i) one or a plurality of 1,2-alkane diols with 5 through 8 carbon atoms and (ii) one or a plurality of ammonium-, sodium- or potassium-R.sup.alk-sarcosinates, wherein the structural element R.sup.alk represents alkanoyl, alkenoyl or alkadienoyl with 12 through 22 carbon atoms, and optionally (iii) one or a plurality of sodium- or potassium-C10-C16-alkyl-sulfoacetates. The invention further relates to particular compositions and cosmetic preparations, in particular body care products, containing said mixture or composition and methods of production thereof. The present invention further relates to the use of said mixture as solubilizer and for increasing the transparency or decreasing the turbidity of a preparation containing one or a plurality of further organic substances.

Claims

1. A method of increasing the solubility of one or a plurality of organic substances, decreasing the turbidity of a preparation containing one or a plurality of organic substances, increasing the transparency of a preparation containing one or a plurality of organic substances, wherein the organic substances have in each case a log K.sub.OW value in the range from 1 through 12, comprising the step of: mixing the one or more organic substances with a solubilizer mixture comprising: (i) one or more 1,2-alkane diols comprising 5-8 carbon atoms, (ii) one or more ammonium-, sodium- or potassium-R.sup.alk-sarcosinates, wherein R.sup.alk is alkanoyl, alkenoyl or alkadienoyl comprising 12-22 carbon atoms, and (iii) optionally one or more sodium- or potassium-C.sub.10-C.sub.16-alkyl-sulfoacetates.

2. The method of claim 1, wherein the preparation is a dispersion and/or an emulsion.

3. The method of claim 1, wherein the solubilizer mixture comprises: (i) one or more 1,2-alkane diols comprising 5-8 carbon atoms, (ii) one or more ammonium-, sodium- or potassium-R.sup.alk-sarcosinates, wherein R.sup.alk is alkanoyl, alkenoyl or alkadienoyl comprising 12-22 carbon atoms, and (iii) one or more sodium- or potassium-C.sub.10-C.sub.16-alkyl-sulfoacetates.

4. The method of claim 1, wherein the solubilizer mixture comprises: (i) one or more 1,2-alkane diols comprising 5-8 carbon atoms, in an amount of from 5 to 30 weight %, (ii) one or more ammonium-, sodium- or potassium-R.sup.alk-sarcosinates, wherein R.sup.alk is alkanoyl, alkenoyl or alkadienoyl comprising 12-22 carbon atoms, in an amount of from 5 to 30 weight %, and (iii) optionally one or more sodium- or potassium-C.sub.10-C.sub.16-alkyl-sulfoacetates in an amount of from 3 to 22 weight %.

5. The method of claim 1, wherein the solubilizer mixture comprises: (i) one or more 1,2-alkane diols comprising 5-8 carbon atoms, in an amount of from 10 to 20 weight %, (ii) one or more ammonium-, sodium- or potassium-R.sup.alk-sarcosinates, wherein R.sup.alk is alkanoyl, alkenoyl or alkadienoyl comprising 12-22 carbon atoms, in an amount of from 10 to 20 weight %, and (iii) optionally one or more sodium- or potassium-C.sub.10-C.sub.16-alkyl-sulfoacetates in an amount of from 5 to 20 weight %.

6. The method of claim 4 wherein (i) is one or more linear 1,2-alkane diols comprising 5-8 carbon atoms.

7. The method of claim 4 wherein (i) is one or more of 1,2-pentanediol, 1,2-hexanediol and 1,2-octanediol.

8. The method of claim 4 wherein (i) is 1,2-pentanediol.

9. The method of claim 4 wherein (ii) is one or more ammonium-, sodium- or potassium-R.sup.alk-sarcosinates, wherein R.sup.alk is alkanoyl, alkenoyl or alkadienoyl comprising 16-22 carbon atoms.

10. The method of claim 4 wherein (ii) is one or more selected from the group consisting of sodium myristoyl sarcosinate, potassium palmitoyl sarcosinate, sodium stearoyl sarcosinate, sodium oleoyl sarcosinate, potassium oleoyl sarcosinate, sodium linoleoyl sarcosinate, potassium lauroyl sarcosinate, potassium cocoyl sarcosinate, sodium cocoyl sarcosinate, ammonium lauroyl sarcosinate, and ammonium cocoyl sarcosinate.

11. The method of claim 4 wherein (ii) is one or more selected from the group consisting of sodium myristoyl sarcosinate, potassium palmitoyl sarcosinate, sodium stearoyl sarcosinate, sodium oleoyl sarcosinate, potassium oleoyl sarcosinate, and sodium linoleoyl sarcosinate.

12. The method of claim 4 wherein (ii) is sodium oleoyl sarcosinate.

13. The method of claim 4 wherein (iii) is present and is one or more sodium- or potassium-C.sub.10-C.sub.14-alkyl-sulfoacetates.

14. The method of claim 4 wherein (iii) is present and is selected from the group consisting of sodium lauryl sulfoacetate, potassium lauryl sulfoacetate, sodium myristyl sulfoacetate, and potassium myristyl sulfoacetate.

15. The method of claim 4 wherein (iii) is sodium lauryl sulfoacetate.

16. The method of claim 1, wherein (i) is 1,2-pentanediol, and (ii) is sodium oleoyl sarcosinate.

17. The method of claim 4 wherein (i) is 1,2-pentanediol, (ii) is sodium oleoyl sarcosinate and (iii) is sodium lauryl sulfoacetate.

Description

EMBODIMENTS THAT ARE PARTICULARLY PREFERRED ACCORDING TO THE INVENTION

Embodiment 1

(1) Use of pentane-1,2-diol in combination with a compound from the group consisting of sodium oleoyl sarcosinate and sodium lauryl sulfoacetate and mixture thereof as solubilizer for one or a plurality of organic substances, for increasing the solubility of one or a plurality of organic substances, for decreasing the turbidity of a preparation, preferably a dispersion and/or emulsion, containing one or a plurality of organic substances,
and/or for increasing the transparency of a preparation, preferably a dispersion and/or emulsion, containing an organic substance,
wherein the organic substance in each case preferably has a log K.sub.OW value in the range from 1 through 12, preferably in the range from 2 through 10, particularly preferably in the range from 3 through 8.

Embodiment 2

(2) Use according to embodiment 1, characterized in that the organic substance has a log K.sub.OW value in the range from 1 through 12, preferably in the range from 2 through 10, particularly preferably in the range from 3 through 8, and is selected from the group of substances suitable for use in cosmetic preparations, preferably in body care products.

Embodiment 3

(3) Mixture comprising pentane-1,2-diol and sodium oleoyl sarcosinate and optionally sodium lauryl sulfoacetate

Embodiment 4

(4) Mixture according to embodiment 3, comprising 5 through 30 wt. %, preferably 10 through 20 wt. %, preferably 12 through 18 wt. %, particularly preferably 13 through 17 wt. % of pentane-1,2-diol, 5 through 30 wt. %, preferably 10 through 20 wt. %, preferably 12 through 18 wt. %, particularly preferably 13 through 17 wt. % of sodium oleoyl sarcosinate, optionally 3 through 22 wt. %, preferably 5 through 20 wt. %, preferably 8 through 20 wt. %, particularly preferably 11 through 17 wt. % of sodium lauryl sulfoacetate,
wherein the percentages by weight refer in each case to the total mass of the mixture.

Embodiment 5

(5) Mixture according to embodiment 3, characterized in that the weight ratio of pentane-1,2-diol to sodium oleoyl sarcosinate is in the range from 5:1 through 1:5, preferably in the range from 3:1 through 1:3, preferably in the range from 2:1 through 1:2, more preferably in the range from 3:2 through 2:3, particularly preferably in the range from 4:3 through 3:4, quite particularly preferably in the range from 8:7 through 7:8.

Embodiment 6

(6) Mixture according to embodiment 3 or 4, comprising or consisting of 10 through 20 wt. %, preferably 12 through 18 wt. %, preferably 13 through 17 wt. %, particularly preferably 14 through 16 wt. % of pentane-1,2-diol, 10 through 20 wt. %, preferably 12 through 18 wt. %, preferably 13 through 17 wt. %, particularly preferably 13 through 16 wt. % of sodium oleoyl sarcosinate, 5 through 20 wt. %, preferably 8 through 18 wt. %, preferably 11 through 17 wt. %, particularly preferably 12 through 16.5 wt. % of sodium lauryl sulfoacetate, 25 wt. % or more of water, preferably 30 through 60 wt. % water, preferably 35 through 55 wt. % water, optionally sodium oleate, preferably 0.5 through 5 wt. % of sodium oleate, preferably 1 through 3 wt. %, optionally sodium chloride, preferably 1 through 5 wt. % of sodium chloride, preferably 1.5 through 4 wt. %, optionally disodium sulfoacetate, preferably 0.5 through 3 wt. %, preferably 0.6 through 2 wt. %, optionally sodium sulfate, preferably 0.5 through 3 wt. %, preferably 1 through 2 wt. %,
wherein the percentages by weight refer in each case to the total mass of the mixture.

Embodiment 7

(7) Mixture according to any of the embodiments 3 through 6, characterized in that the mixture has a pH value of 6 or higher, preferably a pH value of 6.5 or higher.

Embodiment 8

(8) Composition for the production of a cosmetic preparation, preferably of a body care product, comprising a mixture according to any of the embodiments 3 through 7 and one or a plurality of organic substances with a log K.sub.OW value in the range from 1 through 12, preferably in the range from 2 through 10, particularly preferably in the range from 3 through 8.

Embodiment 9

(9) Composition according to embodiment 8, characterized in that the composition is transparent, preferably has a turbidity of less than 10 NTU (nephelometric turbidity units), preferably of less than 5 NTU, particularly preferably of less than 3 NTU.

Embodiment 10

(10) Composition according to embodiment 8 or 9, characterized in that the total amount of organic substance(s) with a log K.sub.OW value in the range from 1 through 12 is in the range from 0.1 through 5 wt. %, preferably in the range from 0.1 through 3 wt. %, preferably in the range from 0.15 through 1 wt. %, particularly preferably in the range from 0.2 through 0.8 wt. %, in each case relative to the total mass of the composition.

Embodiment 11

(11) Cosmetic preparation, comprising

(12) (i) a mixture according to any of the embodiments 3 through 7 and one or a plurality of organic substances with a log K.sub.OW value in the range from 1 through 12, preferably in the range from 2 through 10, particularly preferably in the range from 3 through 8

(13) or

(14) a composition according to any of the embodiments 8 through 10

(15) and

(16) (ii) optionally further cosmetically effective constituents,

(17) (iii) optionally other constituents.

Embodiment 12

(18) Cosmetic preparation according to embodiment 11, characterized in that the cosmetic preparation is selected from the group of body care products, and preferably is selected from the group consisting of aqueous and aqueous-alcoholic systems such as shower gels, shampoos, alcoholic perfumes, aqueous alcoholic perfumes, aftershave gels, creams, lotions, hair care products, hair styling products.

Embodiment 13

(19) Cosmetic preparation according to embodiment 11 or 12, characterized in that the cosmetic preparation, preferably the body care product, comprises

(20) 0.1 through 15 wt. %, preferably 0.5 through 7 wt. %, more preferably 0.5 through 5 wt. %, and particularly preferably 1 through 3 wt. % of a mixture according to any of the embodiments 3 through 7

(21) or

(22) 0.1 through 15 wt. %, preferably 0.5 through 7 wt. %, more preferably 0.5 through 5 wt. %, and particularly preferably 1 through 3 wt. % of a composition according to any of the embodiments 8 through 10

(23) wherein the percentages by weight are in each case relative to the total mass of the cosmetic preparation.

Embodiment 14

(24) Method of increasing the solubility of an organic substance and/or decreasing the turbidity of a preparation containing an organic substance and/or for increasing the transparency of a preparation containing one or a plurality of organic substances,

(25) wherein the organic substance has in each case a log K.sub.OW value in the range from 1 through 12, preferably in the range from 2 through 10, particularly preferably in the range from 3 through 8,

(26) comprising the step:

(27) mixing the organic substance(s) with a mixture according to any of the embodiments 3 through 7.

Embodiment 15

(28) Method of producing a mixture according to any of the embodiments 3 through 7, a composition according to any of the embodiments 8 through 10 or a cosmetic preparation according to any of the embodiments 11 through 13, comprising the step: mixing of pentane-1,2-diol and sodium oleoyl sarcosinate and optionally sodium lauryl sulfoacetate.

Embodiment 16

(29) Use of pentane-1,2-diol for improving the solubilizing action, in particular the dissolving power, of surfactants, preferably of sodium oleoyl sarcosinate, sodium lauryl sulfoacetate or mixture thereof, preferably a mixture of sodium oleoyl sarcosinate and sodium lauryl sulfoacetate in the weight ratio from 10:1 through 1:4, preferably in the weight ratio from 4:1 through 1:2.

(30) The invention is explained in more detail below, on the basis of examples.

Examples

(31) Unless stated otherwise, all figures given refer to weight.

(32) The raw materials used in the following are commercially available.

(33) The Oleoyl sarcosinate HH used in the following consisted of 54 wt. % of sodium oleoyl sarcosinate, 6 wt. % of sodium oleate and 40 wt. % water.

(34) The Lauryl sulfoacetate VV used in the following contained about 67 wt. % of sodium lauryl sulfoacetate, about 14 wt. % of sodium chloride, 3-10 wt. % of disodium sulfoacetate and 7 wt. % of sodium sulfate and had a water content of less than 1.5 wt. %.

Example 1: Solubilizers (According to the Invention and Comparative Tests)

(35) TABLE-US-00002 U.53787M Z1 Z2 Raw material INCI wt. % wt. % wt. % Oleoyl sarcosinate Sodium oleoyl 25.00 25.00 25.00 HH sarcosinate, sodium oleate Hydrolite 5 Pentylene glycol 15.00 15.00 15.00 (pentane-1,2-diol) 1,2-Propylene Propylene glycol 15.00 glycol Glycerol Glycerol 15.00 Lauryl sulfoacetate Sodium lauryl 20.00 20.00 20.00 VV sulfoacetate, sodium chloride, disodium sulfoacetate, sodium sulfate Demineralized water Aqua To 100 To 100 To 100

(36) The mixture according to the invention U.53787M (pH value: 5.5) was light yellow and clear (transparent), whereas the mixtures Z1 and Z2, not according to the invention, were cloudy and contained incompletely dissolved solid constituents. The mixture according to the invention U.53787M remained clear and stable over a storage time of 6 months in daylight and 5 C., 25 C. or 40 C.

Example 2: Mixtures According to the Invention (Solubilizers)

(37) TABLE-US-00003 A B C Raw material INCI wt. % wt. % wt. % Oleoyl sarcosinate Sodium oleoyl 25.00 25.00 25.00 HH sarcosinate, sodium oleate Hydrolite 5 Pentylene glycol 15.00 15.00 15.00 (pentane-1,2-diol) Lauryl sulfoacetate Sodium lauryl 20.00 20.00 20.00 VV sulfoacetate, sodium chloride, disodium sulfoacetate, sodium sulfate NaOH 50% in water Sodium hydroxide 1.11 1.55 2.00 Demineralized water Aqua To 100 To 100 To 100 pH value 6.0 6.5 7.5

(38) These mixtures according to the invention were clear (transparent) and remained clear and stable over a storage time of 6 months in daylight. The mixtures according to the invention A, B and C showed a further improved dissolving power and even better solubilizing properties than U.53787M from example 1.

Example 3: Storage Stability of Compositions and Preparations According to the Invention

(39) The transparency (clarity) of the compositions was determined after 3 months at the constant storage temperature stated in each case.

Example 3.1: Investigations with Menthyl Lactate

(40) TABLE-US-00004 wt. % wt. % wt. % Frescolat ML (menthyl 0.50 0.40 0.40 lactate) Solubilizer U.53787M from 2.00 2.00 example 1 Solubilizer B from example 2 2.00 Glycerol 5.00 5.00 Pentane-1,2-diol 5.00 1,2-Propylene glycol Water To 100 To 100 To 100 Assessment of turbidity Production at 25 clear clear clear Storage at 5 C. clear clear clear Storage at 40 C. clear clear clear

Example 3.2: Investigations with Dragocid Liquid

(41) TABLE-US-00005 wt. % wt. % wt. % wt. % Dragocid Liquid 1.20 1.20 1.20 1.20 Solubilizer U.53787M from 2.00 2.00 2.00 2.00 example 1 Glycerol 5.00 Pentane-1,2-diol 0.50 3.00 1,2-Propylene glycol 0.50 Water To 100 To 100 To 100 To 100 Assessment of turbidity Production at 25 clear clear clear clear Storage at 5 C. clear clear clear clear Storage at 40 C. clear clear clear clear

(42) Dragocid Liquid is a mixture of phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben and isobutylparaben, commercially available from Symrise.

Example 3.3: Investigations with Bisabolol

(43) TABLE-US-00006 wt. % wt. % wt. % wt. % Bisabolol 0.10 0.10 0.10 0.10 Solubilizer U.53787M from 2.00 2.00 2.00 2.00 example 1 Pentane-1,2-diol 0.50 2.50 1,2-Propylene glycol 3.00 1.00 Water To 100 To 100 To 100 To 100 Assessment of turbidity Production at 25 clear clear clear clear Storage at 5 C. clear clear clear clear Storage at 40 C. clear clear clear clear

(44) TABLE-US-00007 wt. % wt. % Bisabolol 0.10 0.20 Solubilizer U.53787M from example 1 2.00 Solubilizer A from example 2 2.00 Glycerol 4.00 5.00 Water To 100 To 100 Assessment of turbidity Production at 25 clear clear Storage at 5 C. clear clear Storage at 40 C. clear clear

Example 3.4: Investigations with Other Organic Substances

(45) TABLE-US-00008 wt. % Organic substance to be investigated x.xx Solubilizer U.53787M from example 1 2.00 Glycerol 5.00 Water To 100 Assessment of turbidity Production at 25 clear Storage at 5 C. clear Storage at 40 C. clear

(46) The following organic substances to be investigated were incorporated in this framework formulation, in each case in an amount of x.xx wt. %, wherein the respective composition or preparation remained clear and stable for the period of storage at the constant temperature stated in each case:

(47) Sage oil (Salvia officinalis oil) (0.10 wt. %), rose oil (Rosa Damascena Flower Oil) (0.20 wt. %), perfume oil Lait de Rose (0.20 wt. %), perfume oil Lait Vitamine Sun (0.30 wt. %), perfume oil LEau dt (0.20 wt. %), perfume oil Jasmin Flowers (0.30 wt. %), paraffin oil (paraffinum liquidum) (0.10 wt. %) or Crinipan AD (climbazole anti-dandruff agent) (0.10 wt. %).

Formulation Examples

(48) In the following formulation examples, the respective phase containing the PEG-free solubilizer U.53787M according to the invention from example 1 was clear and had a turbidity value of less than 3 NTU (as defined above).

(49) The finished formulations of formulation examples F1 through F9 had a turbidity value of less than 10 NTU (as defined above) (examples F1, F2, F5, F7 and F9) or of less than 3 NTU (formulation examples F3, F4, F6 and F8). Only the yellowish-white emulsion of formulation example F10 had a turbidity value of >10 NTU.

Formulation Example F1: Aftershave Gel

(50) TABLE-US-00009 Phase Raw material INCI wt. % A PEG-free solubilizer Aqua, pentylene glycol, 7.00 U.53787M from sodium lauryl example 1 sulfoacetate, sodium oleoyl sarcosinate, sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Hydrolite 5 Pentylene glycol 5.00 SymSitive Pentylene glycol, 4-t- 1.00 butylcyclohexanol Vitamin-E acetate Tocopheryl acetate 0.50 Frescolat ML Menthyl lactate 0.50 Perfume Fragrance 0.15 Glycerol Glycerol 5.00 B Water Water (aqua) To 100 Pemulen TR2 Acrylates/C10-30 alkyl 1.00 acrylate crosspolymer Extrapone Glacier Glycerol, aqua 1.00 Water GW SymCalmin Butylene glycol, 0.50 pentylene glycol, hydroxyphenyl propamidobenzoic acid NaOH 10% in water Sodium hydroxide 3.15 C Tegosoft PC41 Polyglyceryl-4 caprate 2.00 D Ethanol Alcohol 4.80 Blue dye 1% in water Color 0.50

(51) Production: Dissolve the ingredients of phase A with stirring until clear. For phase B, leave the thickener to swell in water, and add the remaining components with stirring. Add phase A to phase B with stirring, add phase C and phase D one after another with stirring.

(52) The pH value of formulation example F1 was 5.9.

Formulation Example F2: Sunscreen Gel with Sun Protection Factor SPF 20-25

(53) TABLE-US-00010 Phase Raw material INCI wt. % A Water Water (aqua) To 100 Neo Heliopan AP, Disodium phenyl 30.00 10% in water, dibenzimidazole neutralized tetrasulfonate with NaOH Neo Heliopan Phenylbenzimidazole 33.34 hydro, 15% in sulfonic acid water, neutralized with NaOH EDETA BD Disodium EDTA 0.10 Dragosine Carnosine 0.20 B Esaflor HDR Hydroxypropyl guar 1.50 C Biotive Troxerutin Troxerutin 1.60 Red dye Color 0.10 D Hydrolite 5 Pentylene glycol 5.00 Perfume Fragrance 0.10 PEG-free Aqua, pentylene glycol, 0.50 solubilizer sodium lauryl sulfoacetate, U.53787M from sodium oleoyl sarcosinate, example 1 sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate SymDiol 68 1,2-Hexanediol, caprylyl 1.00 glycol

(54) Production: Add the ingredients of phase A together. Add the thickener from phase B with stirring and leave to swell. Then add the components of phase C one after another with stirring. For phase D, dissolve the components until clear and add to phase A/B/C with stirring.

(55) The pH value of formulation example F2 was 7.6.

Formulation Example F3: After Sun Gel

(56) TABLE-US-00011 Phase Raw material INCI wt. % A PEG-free Aqua, pentylene glycol, 15.00 solubilizer sodium lauryl sulfoacetate, U.53787M from sodium oleoyl sarcosinate, example 1 sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Glycerol Glycerin 5.00 Natural alpha- Bisabolol 0.10 bisabolol Vitamin-E acetate Tocopheryl acetate 0.50 Sym Repair Hexyldecanol, bisabolol, 0.50 cetylhydroxyproline palmitamide, stearic acid, Brassica campestris sterols SymHelios 1031 Benzylidene 0.10 dimethoxydimethylindanone Perfume Fragrance 0.20 B Water Water (aqua) To 100 Pemulen TR2 Acrylates/C10-30 alkyl 1.00 acrylate crosspolymer D-Panthenol Panthenol, aqua 0.50 Flowerpone Aqua, pentylene glycol, 1.00 Frangipani PEG-40 hydrogenated castor oil, trideceth-9, bisabolol, Plumeria acutifolia flower extract Extrapone Aqua, glycerol, hydrolyzed 1.00 Pearl GW pearl, xanthan gum NaOH 10% in water Sodium hydroxide 3.00 C Ethanol Alcohol 14.40

(57) Production: Dissolve the ingredients of phase A with stirring until clear. For phase B, leave the thickener to swell in water, add the remaining components with stirring. Add phase A to phase B with stirring, add phase C with stirring.

(58) The pH value of formulation example F3 was 5.8.

Formulation Example F4: Clear Body Tonic

(59) TABLE-US-00012 Phase Raw material INCI wt. % A PEG-free Aqua, pentylene glycol, 7.00 solubilizer sodium lauryl U.53787M from sulfoacetate, sodium example 1 oleoyl sarcosinate, sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Frescolat ML Menthyl lactate 0.80 Perfume Fragrance 1.00 B Water Water (aqua) To 100 Hydrolite 5 Pentylene glycol 5.00 Extrapone Bamboo Propylene glycol, aqua, 1.00 butylene glycol, Bambusa vulgaris shoot extract Extrapone Guarana Aqua, propylene glycol, 1.00 Paullinia cupana seed extract, alcohol C Ethanol Alcohol 25.00 Azorubin 0.1% Color 0.10

(60) Production: Dissolve the ingredients of phase A with stirring until clear. Mix the components of phase B and add to phase A with stirring, add phase C one after another with stirring.

(61) The pH value of formulation example F4 was 6.0.

Formulation Example F5: Self Tan Gel

(62) TABLE-US-00013 Phase Raw material INCI wt. % A PEG-free Aqua, pentylene glycol, 15.00 solubilizer sodium lauryl sulfoacetate, U.53787M from sodium oleoyl sarcosinate, example 1 sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Vitamin E acetate Tocopheryl acetate 0.50 Alpha-Bisabolol Bisabolol 0.10 Natural SymHelios 1031 Benzylidene 0.10 dimethoxydimethylindanone Hydrolite 5 Pentylene glycol 2.50 Glycerol Glycerin 5.00 Perfume Fragrance 0.20 B Water Water (aqua) To 100 Pemulen TR2 Acrylates/C10-30 alkyl 1.00 acrylate crosspolymer Dihydroxyacetone Dihydroxyacetone 5.00 D-Panthenol Panthenol 0.50 Extrapone Aqua, butylene glycol, 1.00 Lotus Flower Nelumbo nucifera flower extract NaOH 10% in water Sodium hydroxide 0.70 C Ethanol Alcohol 5.00

(63) Production: Dissolve the ingredients of phase A with stirring until clear. For phase B, leave the thickener to swell in water, add the remaining components with stirring. Add phase A to phase B with stirring, add phase C with stirring.

(64) The pH value of formulation example F5 was 5.0.

Formulation Example F6: Impregnating Solution for Baby Wipes

(65) TABLE-US-00014 Phase Raw material INCI wt. % A PEG-free Aqua, pentylene 10.00 solubilizer glycol, sodium lauryl U.53787M from sulfoacetate, sodium example 1 oleoyl sarcosinate, sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Natural alpha- Bisabolol 0.10 bisabolol Vitamin-E acetate Tocopheryl acetate 0.50 Hydrolite 5 Pentylene glycol 5.00 Glycerol Glycerin 5.00 Tegosoft PC41 Polyglyceryl-4 caprate 1.00 B Water Water (aqua) To 100 D-Panthenol Panthenol, aqua 0.80 DragoCalm Aqua, glycerin, Avena 1.00 sativa kernel extract Allplant Pelargonium graveolens 1.00 Essence Org flower/leaf/stem water Rose Geranium P

(66) Production: Dissolve the ingredients of phase A with stirring until clear. Mix the components of phase B and add to phase A with stirring.

(67) The pH value of formulation example F6 was 6.2.

Formulation Example F7: Alcohol-Free Body Gel

(68) TABLE-US-00015 Phase Raw material INCI wt. % A PEG-free Aqua, pentylene glycol, 10.00 solubilizer sodium lauryl sulfoacetate, U.53787M from sodium oleoyl sarcosinate, example 1 sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Orange Oil Guinea Citrus aurantium dulcis 0.25 Croatian Lavender Oil Lavandula hybrida oil 0.10 Hydrolite 5 Pentylene glycol 5.00 Vitamin-E acetate Tocopheryl acetate 0.50 Tegosoft PC41 Polyglyceryl-4-caprate 2.00 B Water Water (aqua) To 100 Keltrol CG-T Xanthan gum 0.50 Aristoflex TAC Ammonium acryloyl 1.50 dimethyltaurate/carboxyethyl acrylate crosspolymer Aloe Vera Gel Aloe barbadensis gel 0.50 Concentrate 10/1 Dragosine Carnosine 0.10 SymGlucan Aqua, glycerin, beta-glucan 2.00 D-panthenol Panthenol, aqua 0.50 Orange No. 4 dye Color 0.10 0.1%

(69) Production: Dissolve the ingredients of phase A with stirring until clear. For phase B, leave the thickener to swell in water, add the remaining components with stirring. Add phase A to phase B with stirring.

(70) The pH value of formulation example F7 was 6.0.

Formulation Example F8: Cosmetic Preparation with Plant Extracts

(71) TABLE-US-00016 Phase Raw material INCI wt. % A PEG-free Aqua, pentylene glycol, 10.00 solubilizer sodium lauryl U.53787M from sulfoacetate, sodium example 1 oleoyl sarcosinate, sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Milfoil Oil Achillea millefolium oil 0.10 Egyptian Chamomile Oil Chamomilla recutita 0.20 flower oil Natural alpha- Bisabolol 0.10 bisabolol B SymDiol 68 1,2-Hexanediol, caprylyl 0.50 glycol 1,2-Butylene glycol Butylene glycol 40.00 C Water Water (aqua) To 100

(72) Production: Dissolve the ingredients of phase A with stirring until clear. Mix the components of phase B and add to phase A with stirring. Add phase C with stirring.

(73) The pH value of formulation example F8 was 6.2.

Formulation Example F9: Styling Gel

(74) TABLE-US-00017 Phase Raw material INCI wt. % A PEG-free Aqua, pentylene glycol, 7.00 solubilizer sodium lauryl U.53787M from sulfoacetate, sodium example 1 oleoyl sarcosinate, sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate Hydrolite 5 Pentylene glycol 2.50 SymRepair Hexyldecanol, bisabolol, 1.00 cetylhydroxyproline palmitamide, stearic acid, Brassica campestris sterols Perfume Fragrance 0.30 B Water Water (aqua) To 100 Amaze XT Dehydroxanthan gum 2.00 Hubridur 875 Polyurethane-2 and 5.00 polymethyl methacrylate Dragoderm Glycerin, Triticum 2.00 vulgare gluten, aqua Extrapone Silk Aqua, glycerin, 1.00 hydrolyzed silk Symdiol 68 1,2-Hexanediol, caprylyl 1.00 glycol C Ethanol Alcohol 5.00

(75) Production: Dissolve the ingredients of phase A with stirring until clear. For phase B, leave the thickener to swell in water, add the remaining components with stirring. Add phase A to phase B with stirring, add phase C with stirring.

(76) The pH value of formulation example F9 was 6.6.

Formulation Example F10: Sunscreen Emulsion

(77) TABLE-US-00018 Phase Raw material INCI wt. % A Emulsiphos Potassium cetyl 2.50 phosphate, hydrogenated palm glycerides Cithrol GMM Glyceryl myristate 1.00 Neo Heliopan 357 Butyl 5.00 methoxydibenzoylmethane Neo Heliopan OS Ethylhexyl salicylate 5.00 Neo Heliopan 303 Octocrylene 10.00 Neo Heliopan HMS Homosalate 10.00 Tinosorb S Bis-ethylhexyloxyphenol 4.00 methoxyphenyl triazine Neo Heliopan E 1000 Isoamyl p- 2.00 methoxycinnamate Dragoxat 89 Ethylhexyl isononanoate 3.00 SymMollient S Cetearyl nonanoate 2.00 Antaron - Ganex WP 660 Tricontanyl PVP 2.00 Xiameter PMX-0246 Cyclohexasiloxane (and) 2.00 cyclosiloxane cyclopentasiloxane KF-995 Cyclopentasiloxane 2.00 Silcare Silicone 41M65 Stearyl dimethicone 1.00 EDETA BD Disodium EDTA 0.10 Vitamin E acetate Tocopheryl acetate 0.50 Asensa PR 200 Polyethylene 1.00 Keltrol CG-T Xanthan gum 0.50 Eusolex T-AVO Titanium dioxide, silica 2.00 B Water Aqua (water) 21.86 Neo Heliopan Phenylbenzimidazole 13.34 Hydro, 15% in water, sulfonic acid neutralized with NaOH Glycerol Glycerin 3.00 D-Panthenol 75L Panthenol 0.60 NaOH 10% in water Sodium hydroxide 0.90 PEG-free Aqua, pentylene glycol, 2.00 solubilizer sodium lauryl sulfoacetate, U.53787M from sodium oleoyl sarcosinate, example 1 sodium chloride, disodium sulfoacetate, sodium oleate, sodium sulfate C Phenoxyethanol Phenoxyethanol 0.75 SymClariol Decylene glycol 0.25 D Perfume Fragrance 0.20 Orgasol Caresse Polyamide-5 1.50

(78) Production: Dissolve the ingredients of phase A and of phase B separately at 80 C. and add together with stirring. Add phase C at 60 C. to phase A/B with stirring and then homogenize. Leave to cool to room temperature, with stirring. Add phase D and homogenize again.

(79) The pH value of formulation example F10 was 7.3.