HEAT TRANSFER LIQUID FOR A TEMPERATURE CONTROL DEVICE FOR EXTRACORPOREAL CIRCULATION

Abstract

The present application refers to a heat transfer liquid for a temperature control device for human body temperature control during extracorporeal circulation, a temperature control device, the use of heat transfer liquid for extracorporeal circulation and a method of human body temperature control using a heat transfer liquid. The head transfer liquid consists of ethylene glycol or propylene glycol at about 25 volume-percent to about 35 volume-percent, hydrogen peroxide at 0.05 volume-percent or less and sterile, filtered and de-mineralized water as rest.

Claims

1. A heat transfer liquid for human body temperature control during extracorporeal circulation, the heat transfer liquid comprising a glycol disinfectant to inhibit microbial growth, the heat transfer liquid being deliverable from a temperature control device to a heat exchanger located separately from a temperature control device.

2. The heat transfer liquid of claim 1 wherein the heat transfer liquid comprises at least 25 volume percent of glycol.

3. The heat transfer liquid of claim 2 wherein the glycol is selected from the group consisting of ethylene glycol and propylene glycol.

4. The heat transfer liquid of claim 3 further comprising less than about 0.05 volume percent hydrogen peroxide.

5. The heat transfer liquid of claim 4 further comprising at least 65 volume percent of water.

6. The heat transfer liquid of claim 1 wherein the heat transfer liquid comprises no more than 35 volume percent glycol.

7. The heat transfer liquid of claim 6 wherein the heat transfer liquid comprising at least 25 volume percent of glycol.

8. The heat transfer liquid of claim 3 wherein the heat transfer liquid comprises about 30 volume percent glycol.

9. The heat transfer liquid of claim 1 wherein the heat exchanger has a first inlet to receive the heat transfer liquid and a first outlet to remove heat transfer liquid and further wherein the heat exchanger has a second inlet to receive blood from the human body and a second outlet to remove the blood from the heat exchanger.

10. A temperature control system for human body temperature control during extracorporeal circulation, comprising: a temperature control liquid including a disinfectant comprising glycol to inhibit microbial growth; a temperature control device adapted to heat or cool the temperature control liquid; a heat exchanger having a blood flow portion and a temperature control liquid flow portion, the heat exchanger configured to alter the temperature of blood flowing through the blood flow portion; and a display coupled to and providing information about the temperature control system; wherein the temperature control device and the heat exchanger are connected with tubing such that flow of temperature control liquid into the heat exchanger is substantially perpendicular to the flow of at least one blood inlet into the heat exchanger.

11. The temperature control system of claim 10 wherein the heat exchanger has a first inlet to receive the heat transfer liquid and a first outlet to remove heat transfer liquid and further wherein the heat exchanger has a second inlet to receive blood from the human body and a second outlet to remove the blood from the heat exchanger.

12. The temperature control system of claim 10 further comprising a computer interface and wherein the temperature control system is adapted to heat or cool the heat transfer liquid based on an input provided by a user at the computer interface.

13. The temperature control system of claim 10 further comprising a disinfectant sensor for measuring a concentration of the disinfectant in the temperature control liquid.

14. The temperature control system of claim 13 wherein the display provides an indication of the disinfection status of the temperature control liquid.

15. The temperature control system of claim 14 wherein the indication includes a recommendation to add disinfectant or exchange the temperature control liquid.

16. The temperature control system of claim 14 wherein the display further provides an indication of the measured concentration of the disinfectant.

17. The temperature control system of claim 10 wherein the temperature control liquid includes at least 25 volume percent of glycol.

18. The temperature control system of claim 10 wherein the temperature control liquid includes no more than 35 volume percent of glycol.

19. The temperature control system of claim 10 wherein the temperature control liquid includes hydrogen peroxide.

20. The temperature control system of claim 10 wherein the flow of temperature control liquid into the heat exchanger is substantially perpendicular to the flow of a blood inlet into the heat exchanger and a blood outlet out of the heat exchanger.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0019] FIG. 1 shows a schematic diagram illustrating a temperature control device in a heat exchanging system.

DETAILED DESCRIPTION OF PREFERRED EMBODIMENT

[0020] FIG. 1 shows a schematic diagram of a heat exchanger 10 for human body temperature control during extracorporeal circulation. The heat exchanger 10 comprises a blood side 12 and a heat transfer liquid side 14 in which blood and a heat transfer liquid are respectively circulated.

[0021] The temperature of the heat transfer liquid used in the heat exchanger 10 is controlled by a heater and/or cooler 24, i.e. a temperature control device. The heater and/or cooler 24 is a device which is capable of heating or cooling or heating and cooling the heat transfer liquid. Preferably, the heater or cooler is capable of both heating and cooling the heat transfer liquid so that a defined temperature of the heat transfer liquid can be maintained. The heater and/or cooler 24 is part of a heat transfer liquid side circuit 26 in which the heat transfer liquid is circulated for operating the heat exchanger 10 in controlling the temperature of the human body of a patient.

[0022] The heater and/or cooler 24 may be provided with a disinfectant sensor 16 configured for measuring a concentration of a disinfectant in the heat transfer liquid in the heater and/or cooler 2. The result of the measurement of the sensor 16 may be transmitted to a computer 18 which may control a first display 20 which may indicate the measured concentration of disinfectant in the heat transfer liquid and a second display 22 which may indicate the consequence of the measured concentration. In particular, the second display 22 may indicate whether the disinfection status of the heat transfer liquid is ok, whether disinfectant is to be added or whether the heat transfer liquid is to be exchanged.

[0023] The heat transfer liquid circulated in the heat transfer liquid side circuit 26 of the present embodiment consists of ethylene glycol or propylene glycol at 30 volume-percent, hydrogen peroxide at 0.02 volume-percent and sterile, filtered and de-mineralized water as rest. In particular the hydrogen peroxide may be considered by the sensor 16 as disinfectant and a concentration of hydrogen peroxide may be measured by the sensor 16, But also a concentration of ethylene glycol or propylene glycol can be determined by the sensor 16 or a different sensor.

[0024] Measuring the concentration of disinfectant, be it hydrogen peroxide, ethylene glycol or propylene glycol is, however, optional and not essential for the present disclosure.