Chinese Medicine Composition for Treating Gastric Reflux
20200261532 ยท 2020-08-20
Inventors
Cpc classification
A61K36/899
HUMAN NECESSITIES
A61K36/48
HUMAN NECESSITIES
A61K36/73
HUMAN NECESSITIES
A61K35/618
HUMAN NECESSITIES
A61K36/899
HUMAN NECESSITIES
A61K2300/00
HUMAN NECESSITIES
A61K2300/00
HUMAN NECESSITIES
A61K36/9066
HUMAN NECESSITIES
A61K36/48
HUMAN NECESSITIES
A61K36/9066
HUMAN NECESSITIES
International classification
A61K36/9066
HUMAN NECESSITIES
A61K36/73
HUMAN NECESSITIES
A61K35/618
HUMAN NECESSITIES
Abstract
A Chinese medicine composition for treating gastric reflux, comprising the following raw materials in parts by weight: 2-15 g of turmeric root tuber, 2-10 g of Gardenia jasminoides, 2-15 g of bamboo shavings, 2-10 g of Panax notoginseng, 3-12 g of ginger, 10-30 g of nacre, 3-12 g of fermented soybean, 5-20 g of cuttlebone, 3-12 g of honey-fried licorice root, 5-25 g of loquat leaf, 3-15 g of dried tangerine peel, 5-25 g of dandelion, and 5-25 g of jujube. The preparation method comprises the following steps: collecting and washing the raw materials; boiling the raw materials in water; combining, concentrating and cooling filtrates; adding ethanol so that the alcohol content is 20-80%; recovering ethanol; concentrating a supernatant into a thick paste; and saving the thick paste for later use. The thick paste is dried and prepared into corresponding formulations, including pills, tablets, powders, granules or soup bags.
Claims
1. A Chinese medicine composition for treating gastric reflux, comprising the following raw materials in parts by weight: 2-15 g of turmeric root tuber, 2-10 g of Gardenia jasminoides, 2-15 g of bamboo shavings, 2-10 g of Panax notoginseng, 3-12 g of ginger, 10-30 g of nacre, 3-12 g of fermented soybean, 5-20 g of cuttlebone, 3-12 g of licorice root, 5-25 g of loquat leaf, 3-15 g of dried tangerine peel, 5-25 g of dandelion, and 5-25 g of jujube.
2. The Chinese medicine composition according to claim 1, comprising the following raw materials in parts by weight: 8-12 g of turmeric root tuber, 4-7 g of Gardenia jasminoides, 8-12 g of bamboo shavings, 2-5 g of Panax notoginseng, 3-5 g of ginger, 20-27 g of nacre, 5-8 g of fermented soybean, 12-17 g of cuttlebone, 5-8 g of licorice root, 10-20 g of loquat leaf, 7-10 g of dried tangerine peel, 12-17 g of dandelion, and 12-17 g of jujube.
3. The Chinese medicine composition according to claim 1, comprising the following raw materials in parts by weight: 10 g of turmeric root tuber, 5 g of Gardenia jasminoides, 10 g of ginger-fried bamboo shavings, 3 g of Panax notoginseng, 2 pieces of ginger, 25 g of nacre, 6 g of fermented soybean, 15 g of cuttlebone, 6 g of honey-fried licorice root, 15 g of loquat leaf, 9 g of dried tangerine peel, 15 g of dandelion, and 15 g of jujube.
4. The Chinese medicine composition according to claim 1, wherein the bamboo shavings is ginger-fried bamboo shavings.
5. The Chinese medicine composition according to claim 4, wherein the ginger-fried bamboo shavings is made of bamboo shavings and ginger by any one process of frying, steaming or baking.
6. The Chinese medicine composition according to claim 1, wherein the licorice root is honey-fried licorice root.
7. The Chinese medicine composition according to claim 6, wherein the preparation method of the honey-fried licorice root comprises the following steps: the honey is firstly refined into medium honey in a pot, then stirred evenly with licorice root slices over a slow fire, taken out from the pot, and then baked in a curing barn or a baking oven at 60-70 C. until hands don't stick, then taken out and cooled in air.
8. The Chinese medicine composition according to claim 7, wherein the weight ratio between the licorice root and the honey is 4-5: 1-2.
9. The Chinese medicine composition according to claim 1, wherein the Chinese medicine composition is formulated into pills, tablets, powders, granules or soup bags.
Description
DESCRIPTION OF THE EMBODIMENTS
[0052] The invention will be further illustrated below in detail in conjunction with the following embodiments.
Embodiment 1
[0053] Collecting 2 g of turmeric root tuber, 2 g of Gardenia jasminoides, 2 g of ginger bamboo shavings, 2 g of Panax notoginseng, 2 pieces of ginger, 10 g of nacre, 3 g of fermented soybean, 5 g of cuttlebone, 3 g of honey-fried licorice root, 5 g of loquat leaf, 3 g of dried tangerine peel, 5 g of dandelion, and 5 g of jujube and washing, boiling the raw materials in water; combining, concentrating and cooling filtrates, adding ethanol so that the alcohol content is 20-80%, recovering ethanol, concentrating a supernatant into a thick paste; and saving the thick paste for later use. Into the thick paste is added -cyclodextrin, heated to dissolve, stirred, filtered, and spray dried at an inlet hot air temperature of 180 C. and an outlet air temperature of 80 C. Flavouring agent is added into the spray-dried powders and blended evenly. The materials are processed by dry granulation at 40 C., integrated into granules and packaged into bags, to obtain the granules of the invention for treating gastric reflux by recovering the elasticity of the sphincter.
Embodiment 2
[0054] Collecting 15 g of turmeric root tuber, 10 g of Gardenia jasminoides, 15 g of ginger bamboo shavings, 10 g of Panax notoginseng, 2 pieces of ginger, 30 g of nacre, 12 g of fermented soybean, 20 g of cuttlebone, 12 g of honey-fried licorice root, 25 g of loquat leaf, 15 g of dried tangerine peel, 25 g of dandelion, and 25 g of jujube and washing, boiling the raw materials in water; combining, concentrating and cooling filtrates, adding ethanol so that the alcohol content is 20-80%, recovering ethanol, concentrating a supernatant into a thick paste; and saving the thick paste for later use. Into the thick paste is added -cyclodextrin, heated to dissolve, stirred, filtered, and spray dried at an inlet hot air temperature of 180 C. and an outlet air temperature of 80 C. Flavouring agent is added into the spray-dried powders and blended evenly. The materials are processed by dry granulation at 40 C., integrated into granules and packaged into bags, to obtain the granules of the invention for treating gastric reflux by recovering the elasticity of the sphincter.
Embodiment 3
[0055] Collecting 15 g of turmeric root tuber, 8 g of Gardenia jasminoides, 10 g of ginger bamboo shavings, 10 g of Panax notoginseng, 2 pieces of ginger, 20 g of nacre, 12 g of fermented soybean, 10 g of cuttlebone, 8 g of honey-fried licorice root, 20 g of loquat leaf, 15 g of dried tangerine peel, 20 g of dandelion, and 20 g of jujube and washing, boiling the raw materials in water; combining, concentrating and cooling filtrates, adding ethanol so that the alcohol content is 20-80%, recovering ethanol, concentrating a supernatant into a thick paste; and saving the thick paste for later use. Into the thick paste is added 95% ethanol twice the weight of the paste, stirred thoroughly and left stand for 24 to 48 hours at room temperature, taking the supernatant. The precipitate is washed with 65% ethanol for 1 to 2 times. The washing liquid is combined with the supernatant, and if there is any alcohol extract, it is also combined with the supernatant, filtered and clarified, then charged into a reduced pressure concentration tank or an alcohol recovery tower to recover ethanol until the medicine liquid has no alcohol taste. The medicine liquid is diluted with distilled water, heated to 100 C. for the colloid aggregation, adjusted to pH 4.5-5.0, then stored at low temperature for 24 hours so that the aggregated colloid can be precipitated, and then filtered to clarification, into which is then added a proper amount of corrective agent and preservative and left stand, then filtered and clarified, and stored at low temperature. The final purification and filtration should be done before filling, and the filtrate should be checked to be clear by a light detector, and then sealed in nutrition bottles with straight tubes and easy-open caps on a machine, with each oral liquid bottle filled with 10 ml, that is the oral liquid of the invention for treating gastric reflux by recovering the elasticity of the sphincter.
Embodiment 4
[0056] Collecting 10 g of turmeric root tuber, 5 g of Gardenia jasminoides, 10 g or ginger bamboo shavings, 3 g of Panax notoginseng, 2 pieces of ginger, 25 g of nacre, 6 g of fermented soybean, 15 g of cuttlebone, 6 g of honey-fried licorice root, 15 g of loquat leaf, 9 g or dried tangerine peel, 15 g of dandelion, and 15 g of jujube and washing, boiling the raw materials in water; combining, concentrating and cooling filtrates, adding ethanol so that the alcohol content is 20-80%, recovering ethanol, concentrating a supernatant into a thick paste; and saving the thick paste for later use. Into the thick paste is added -cyclodextrin, heated to dissolve, stirred, filtered, and spray dried at an inlet hot air temperature of 180 C. and an outlet air temperature of 80 C. Flavouring agent is added into the spray-dried powders and blended evenly. The materials are processed by dry granulation at 40 C., integrated into granules and packaged into bags, to obtain the granules of the invention for treating gastric reflux by recovering the elasticity of the sphincter.