Device for applying a product to be distributed on the skin of a user by iontophoresis
10729899 ยท 2020-08-04
Assignee
Inventors
Cpc classification
A61N1/30
HUMAN NECESSITIES
A61N1/325
HUMAN NECESSITIES
International classification
Abstract
A device for applying a product to be distributed on user's skin by iontophoresis, includes a body intended to receive the product to be distributed, including an electric current generator; and an applicator head mounted on the body, the applicator head including: a device for distributing the product to be distributed on the skin; and a first electrode and a second electrode that are separated by an interelectrode zone, the first electrode and the second electrode to receive an electric current from the generator.
Claims
1. A device for applying a product to be distributed on skin of a user by iontophoresis, the device comprising: a body intended to receive the product to be distributed and comprising an electric current generator; and, an applicator head mounted on the body, the applicator head having an upper interface to be applied against the user's skin, the applicator head comprising: at least one distribution means for distributing the product to be distributed on the skin; a first electrode and a second electrode separated by an inter-electrode zone, the first electrode and the second electrode being arranged, respectively, in a first cavity and a second cavity of the applicator head, the inter-electrode zone being formed by an assembly member that has a bottom part, a side wall and an upper surface, the side wall connecting the bottom part to the upper surface, said assembly member arranged between the first electrode and the second electrode and separating the first cavity in which the first electrode is arranged, from the second cavity, in which the second electrode is arranged, the first electrode and the second electrode being set back from said upper surface of the assembly member so that the upper surface of the assembly member is provided closer to the upper interface than the first electrode and the second electrode, the first electrode and the second electrode arranged to receive an electric current from said generator, and a distribution circuit containing distribution channels for distributing the product toward the at least one distribution means, the distribution channels including a first distribution channel having an outlet arranged at a bottom of the first cavity to supply the product in said first cavity and a second distribution channel having an outlet arranged at a bottom of the second cavity to supply the product in said second cavity.
2. The device according to claim 1, wherein the first electrode and the second electrode are situated in a same plane.
3. The device according to claim 2, wherein the upper surface of the assembly member of the inter-electrode zone is situated in a plane parallel to said plane of the first electrode and the second electrode, the plane of the first electrode and the second electrode and the plane of the upper surface of the assembly member of the inter-electrode zone being situated at a predetermined distance from each other.
4. The device according to claim 1, wherein the upper surface of the assembly member of the inter-electrode zone defines an application surface intended to be in contact with the user's skin.
5. The device according to claim 1, wherein the upper surface of the assembly member of the inter-electrode zone has a predetermined minimum distance between the first electrode and the second electrode which is between 5 and 20 mm.
6. The device according to claim 1, wherein the first electrode and the second electrode are arranged downstream from the distribution circuit.
7. The device according to claim 1, wherein the first electrode and the second electrode each have a wall with perforations.
8. The device according to claim 7, wherein the at least one distribution means comprises one or more outlet openings, and wherein the perforations constitute the one or more outlet openings for distributing the product toward the user's skin.
9. The device according to claim 1, further comprising a plate with perforations arranged in the applicator head, the at least one distribution means comprising one or more outlet openings and the perforations constituting the one or more outlet openings for distributing the product toward the user's skin.
10. The device according to claim 1, wherein the product is contained in a cartridge removably connected to the body of the device.
11. The device according to claim 1, wherein the body comprises at least one means for extracting the product from the body toward the applicator head.
12. The device according to claim 1, wherein the applicator head comprises an electrical insulation means which is fluidically interposed between the first electrode and the second electrode, the electrical insulation means being configured so as to permit or prevent passage of the electric current from the first electrode and the second electrode to the body.
13. The device according to claim 12, wherein the electrical insulation means is adapted to be in: a closed position in which the electric current circulates only between the first electrode and the second electrode; or, an open position in which the electric current circulates between the first electrode and the second electrode and in the distribution channels of the applicator head for distributing the product.
14. The device according to claim 13, wherein the electrical insulation means is in the open position when a pressure inside the electrical insulation means reaches a predetermined threshold.
15. The device according to claim 13, wherein the electrical insulation means is arranged on one of the distribution channels leading to the first electrode.
16. The device according to claim 12, wherein the electrical insulation means is a valve.
17. The device according to claim 1, wherein the first electrode is arranged at a center of the applicator head and the second electrode is arranged toward a periphery of the applicator head.
18. The device according to claim 1, wherein the first electrode and the second electrode are set back from said upper surface of the assembly member of the inter-electrode zone so that the first electrode and the second electrode are not in contact with the user's skin during distribution of the product on the user's skin by iontophoresis.
Description
5. LIST OF FIGURES
(1) Other innovative characteristics and advantages will be seen in the following description, provided for reference and in no way restrictive, in reference to the attached drawings, in which:
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6. DETAILED DESCRIPTION
(13) In reference to
(14) The device comprises a body 2 forming a gripping device of the device 1 and an applicator head 3 mounted on the body 2. As visible in
(15) The term product within the meaning of the invention refers to a product in the form of a fluid such as a liquid and/or an aqueous composition.
(16) In reference to
(17) To facilitate comprehension of the invention, we consider that the applicator head 3 extends along a vertical longitudinal axis Z. A horizontal axis X is also represented, which is perpendicular to the vertical longitudinal axis Z and a transverse axis Y such that these three axes X, Y, Z form a right-handed coordinate system as illustrated in
(18) Illustrated more precisely in
(19) On
(20) The application device comprises at least a first electrode 17 and at least a second electrode 18 for iontophoresis. These first and second electrodes 17, 18 are each installed in at least one distribution cavity 92 contained by the application device 1 and able to receive the product to be distributed. In particular, the distribution cavity 92 is formed in the applicator head 3 and is in fluidic communication with at least one distribution opening 91. We observe more precisely on
(21) Advantageously, but not restrictively, the distribution means 11 comprises one or more product outlet openings toward the user's skin, ending at the upper interface of the applicator head 3.
(22) According to a characteristic of the invention, the first electrode 17 and the second electrode 18 each have a wall 27 with perforations 28.
(23) According to a first embodiment illustrated in
(24) According to a second embodiment illustrated in
(25) The first and second electrodes 17, 18 may be arranged in various ways above the upper surface 5 of the base 4. In one embodiment, as illustrated on
(26) In the various embodiments described, the applicator head 3 comprises at least one electrical insulation means 33 which is fluidically interposed between the first electrode 17 and the second electrode 18. This electrical insulation means 33 is configured so as to permit or limit, or even prevent, the passage of electric current between the first electrode 17 and the second electrode 18 via the applicator head 3. In reference to
(27) Advantageously, but not restrictively, the electrical insulation means 33 is situated close to the distribution opening 91 of the distribution channel 16 leading to the first electrode 17 in order to limit as much as possible the leakage currents toward the second electrode 18 via the applicator head.
(28) To permit or limit the passage of current between the first electrode 17 and the second electrode 18 via the applicator head 3, the electrical insulation means 33 is able to be in an open position or a closed position. In the closed position, current circulates only between the first electrode 17 and the second electrode 18, and in the open position, current circulates in a limited manner in the applicator head 3 and in the body 2. The electrical insulation means 33 has a clearance area which, when the electrical insulation means 33 is in the open position, permits the circulation of electric current between the first and the second electrodes 17, 18 and in the distribution channels 16 of the applicator head 3. Nevertheless, this clearance area is so small that the impedance of the path to travel is too great to favor circulation of current via this clearance area. Thus, the electric current circulates almost exclusively in the application interface (skin side) rather than toward the interior of the applicator head 3 and the body 2.
(29) In the open position, the product to be distributed circulates from the body 2 toward the first and second electrodes 17, 18, while in the closed position, the product no longer circulates toward the first electrode 17. Once the product is again extracted from the storage means 84 toward the buffer reservoir 13, the pressure of the product causes the electrical insulation means 33 to open such that the first and second electrode 17, 18 for iontophoresis are supplied with product. The opening pressure of the electrical insulation means 33 is chosen appropriately in relation to the distribution channels 16 supplying the second electrode 18 and the associated pressure loss. Ideally, the pressure loss undergone by the product to be distributed in the passage of the insulation means 33 is equal to the pressure loss of the longer distribution channels 16 supplying the second electrode 18. Alternatively, electrical insulation means 33 may also be arranged on the distribution channels 16 leading to the second electrode 18 for iontophoresis. This advantageously permits balancing the product's circulation toward the first and second electrodes 17, 18 for iontophoresis, and thus optimizing equal supply of product to the first and second electrodes 17, 18 for iontophoresis.
(30) In addition, the insulation means 33 is in the open position when a pressure inside the insulation means 33 reaches a predetermined threshold. Advantageously, but not restrictively, the insulation means 33 is a valve, and preferably, a check valve as illustrated in
(31) The valve is made of a polymer material, such as silicone.
(32) The applicator head 3 comprises the cap 37 or cover secured to the base 4 to hold the first and second electrodes 17, 18 in position in the applicator head 3. The cap 37 comprises the collar 38 which has a central opening 39 through which the base 4 is received. The first and second electrodes 17, 18 as well as the assembly member (application surface 20) are visible through this central opening 39. The collar 38 has an upper surface 101 which is defined in a plane D. This upper surface 101 forms a support ring whose purpose is to create a volume with a low thickness on the skin. This plane D is roughly parallel to the plane C of the application surface 20 of the inter-electrode zone 19. The plane D is also parallel to the plane B of the first and second electrodes 17, 18 for iontophoresis. The collar 38 of the cap 37 includes in its periphery a side skirt 40 intended to cooperate with the wall 7 of the base 4. In particular, between the side skirt 8 and the wall 7 of the base 4, there is provided a flange 41 on which rests a free end 42 of the side skirt 40. The wall 7 of the base 4 also has blind slots 43 (see
(33) Between the inner wall 45 of the side skirt 40 of the cap 37 and the wall 7 of the base 4 is arranged a first gasket 46. In order for the first gasket 46 to be held in position, the wall 7 of the base 4 includes a groove 47 extending in the direction of the perimeter of the wall 7. The first gasket 46 has a ring-shaped body. Advantageously, the first gasket 46 is made of an elastically deformable material. This deformable material is preferably a polymer or a copolymer chosen from one of the following: an ethylene propylene diene monomer (EPDM), a fluorocarbon rubber (FPM), a polyacrylic elastomer (ACM), an ethylene-acrylic copolymer (AEM), a hydrogenated nitrile rubber (HNBR), a VITON, or a butyl.
(34) The applicator head 3 further comprises a connecting member 48 to removably connect the applicator head 3 and the body 2 (see
(35) Advantageously, the product to be distributed is contained in a cartridge 63 which is removably connected to the body 2 of the device. Thus, when the product is exhausted, the cartridge 63 may easily be replaced or refilled.
(36) In reference to
(37) The body 2 comprises at least one extraction means 78 to permit extracting the product in the storage means 84 from the body 2. This means 78 may be manual or motorized. In manual mode, the device may comprise a drive means comprising a portion 83 (see
(38) As a variant, the motorized extraction means 78 comprises a motor (not represented) activating means to permit rotating a distribution mechanism. The motor may be activated via a button accessible on the body 2 of the application device 1. This button is connected to an electronic control circuit 72 to activate the motor.
(39) In the body 2 is also arranged a current generator 71 to permit delivering a low-intensity current to the first and second electrodes 17, 18 arranged in the applicator head 3. The electric current is between 50 microamperes (A) and 6000 A. Preferably, but not restrictively, the electric current is approximately 800 A. The current may be alternating or direct. The electric current generator 71 is controlled by the electronic control circuit 72 installed in the body 2 of the product application device 1 to provide the current. The electronic control circuit 72 is powered by an electric power source 90 that may be a battery or a rechargeable battery on a household power supply grid. Alternatively, the device 1 may comprise an electric power cord (not represented) intended to be connected to the household power supply grid and to power the electronic control circuit 72. To ensure an electrical connection between the current generator 71 and the first and second electrodes 17, 18, these electrodes are each equipped with a pin 73, 73. The pins 73, 73 and the first and second electrodes 17, 18 are formed of a single part. Each pin 73, 73 (see
(40) On
(41) According to a characteristic of the invention, when the product is distributed, a closed circuit is formed with the user's skin, the first electrode 17 and the second electrode 18. In order to avoid skin microlesions creating sensations of discomfort or even pain in the case of strong intensity or prolonged duration, or to detect a problem with functioning or tolerance, the device may include a temperature probe. Advantageously, this temperature probe is integrated in the applicator head 3 of the application device 1 and connected to the electronic control circuit 72.
(42) We will now describe the functioning of the application device. When the application device is powered up, the electronic control circuit 72 sends an order to the current generator 71 which generates a current at the first and second electrodes 17, 18 for iontophoresis. The user activates the extraction means 78 until the product is extracted from the cartridge 63 and collected in the buffer reservoir 13 as a first step. As a second step, the product under pressure triggers the opening of the valve, when the pressure inside the valve reaches a predetermined value, which permits the product to pass into the distribution channels 16 formed in the base 4. The product then empties into the distribution cavity 92 via the distribution openings 91 toward the first and second electrodes 17, 18. The product going through the perforations 28 of the first and second electrodes 17, 18 to the right of the electric field created is transported deep into the skin following the semicircular arched field lines. The distance reached under the skin is between 2 and 10 mm deep.
(43) The invention is described in the preceding as an example. It is understood that those skilled in the art are able to carry out different embodiment variants of the invention, for example, by combining the various above characteristics taken alone or in combination, without departing from the context of the invention.