Ultrasound imaging system with a transmit pulse sequence generator circuit
10687782 ยท 2020-06-23
Assignee
Inventors
Cpc classification
A61B8/4483
HUMAN NECESSITIES
A61B8/481
HUMAN NECESSITIES
A61B8/44
HUMAN NECESSITIES
International classification
Abstract
A method and apparatus of generating a sequence of pulses by a transmit signal generator. The transmit signal generator has a multiplexer that is connected to a binary counter and one of the output lines of the binary counter provides the sequence of pulses.
Claims
1. A transmit signal generator for generating a sequence of pulses, comprising: a 2.sup.n-to-1 multiplexer having 2.sup.n input lines, one of the 2.sup.n input lines being connected to ground or zero potential, n selector lines connected to a selector signal and an output line providing an output of the multiplexer, the multiplexer operable to select one of the 2.sup.n input lines as the output of the multiplexer based on the selector signal; and a 2.sup.n-bit binary counter having a clock signal input line connected to a clock signal input, a reset signal input line connected to a reset signal input, a clock enable line connected to the output line of the multiplexer providing the output of the multiplexer as an input signal for the clock enable line, and 2.sup.n output lines, one of the 2.sup.n output lines providing a sequence of pulse as an output of the transmit signal generator and the remaining 2.sup.n output lines of the binary counter each connected to one of the remaining 2.sup.n input lines of the multiplexer; wherein the output of the transmit signal generator provides a continuous pulse or an N pulse sequence as the output based on the selector signal and the reset signal input initiating generation of the sequence of pulses, wherein N2.sup.n and n is an integer.
2. The transmit signal generator of claim 1, further comprising an inverter between the output line of the multiplexer and the clock enable line for inverting the output of the multiplexer and providing the inverted output as the input signal for the clock enable line of the binary counter.
3. The transmit signal generator of claim 1, wherein the one of the 2.sup.n input lines connected to ground or zero potential is a least significant bit of the input lines of the multiplexer.
4. The transmit signal generator of claim 1, wherein the one of the 2.sup.n output lines providing the sequence of pulses as the output is a least significant bit of the 2.sup.n output lines of the binary counter.
5. The transmit signal generator of claim 1, wherein N is 1 or x, and x=2.sup.n.
6. The transmit signal generator of claim 1, wherein the selector signal is set to 00, 01, 10 and 11 to provide the sequence of a continuous, single, two and four pulse output, respectively, as the output of the transmit signal generator.
7. The transmit signal generator of claim 1, wherein the clock signal input for the binary counter has a frequency of H Hz and the output of the transmit signal generator has a frequency of H/2.sup.n Hz.
8. The transmit signal generator of claim 1, wherein the binary counter is a 2.sup.n-bit frequency counter comprising 2.sup.n Toggle flip-flop (T-FF) circuits and (2.sup.n-2) AND gates.
9. The transmit signal generator of claim 8, wherein at least one of the T-FF circuits comprises a Data flip-flop (D-FF) circuit and an inverter.
10. The transmit signal generator of claim 8, wherein at least one of the T-FF circuits comprises a Data flip-flop (D-FF), two inverters, two AND gates and an OR gate.
11. An ultrasound imaging system, comprising the transmit signal generator of claim 1.
12. The transmit signal generator of claim 1, further comprising: at least one (2.sup.n-2) integer-number detector circuit; each of the 2.sup.n output lines of the binary counter connected to each of the at least one integer-number detector circuit as input; and each of the at least one integer-number detector circuit having an output line connected to one of the remaining 2.sup.n input lines of the multiplexer, wherein N is a positive integer number.
13. The transmit signal generator of claim 12, wherein each of the at least one integer-number detector circuit comprise an AND gate and a plurality of inverters.
14. The transmit signal generator of claim 12, wherein the selector signal is set to 00, 01, 10 and 11 respectively to provide the sequence of a continuous, single, three and five pulse output as the output of the transmit signal generator.
15. A method of generating a sequence of pulses, comprising the steps of: providing a 2.sup.n-to-1 multiplexer having 2.sup.n input lines, n selector lines and an output line providing an output of the multiplexer; connecting one of the 2.sup.n input lines to ground or zero potential; providing a selector signal to the n selector lines for selecting one of the 2.sup.n input lines of the multiplexer as the output of the multiplexer based on the selector signal; providing a 2.sup.n-bit binary counter having a clock signal input line, a reset signal input line, a clock enable line, and 2.sup.n output lines; providing a clock signal input to the clock signal input line and a reset signal input to the reset signal input line; and providing an input signal for the clock enable line by connecting the clock enable line to the output line of the multiplexer, the binary counter providing an output signal based on the clock signal input, the reset signal input and the input signal for the clock enable line; wherein one of the 2.sup.n output lines providing a sequence of pulse as an output of the transmit signal generator, each of the remaining 2.sup.n output lines of the binary counter is connected to one of the remaining 2.sup.n input lines of the multiplexer, the output of the transmit signal generator is providing a continuous pulse or an N pulse sequence as the output based on the selector signal and the reset signal input initiates generation of the sequence of pulses, wherein N2.sup.n and n is an integer.
16. The method of claim 15, further comprising: providing at least one (2.sup.n-2) integer-number detector circuit; and connecting each of the 2.sup.n output lines of the binary counter to each of the at least one integer-number detector circuit as input, each of the at least one integer-number detector circuit having an output line connected to one of the remaining 2.sup.n input lines of the multiplexer, wherein N is a positive integer number.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1) The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the principle of the invention. In the drawings:
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DETAILED DESCRIPTION OF THE INVENTION
(20) For simplicity and clarity, the Figures of the present disclosure illustrate a general manner of construction of various embodiments. Descriptions and details of well-known features and techniques may be omitted to avoid unnecessarily obscuring the discussion of described embodiments of the present disclosure. It should be understood that the elements of the Figures are not necessarily drawn to scale, and that the dimensions of some elements may be exaggerated relative to other elements for enhancing understanding of described embodiments.
(21) The proposed technology is discussed herewith in detail in reference to the Figures. This disclosure describes various embodiments related to a ultrasound transmit (Tx) pulse sequence generator circuit (PSGC) that generates a pulse signal with a selectable number of pulses. This circuit is compact, flexible, low-power, comparable with digital technology, easily implementable on a FPGA (Field Programmable Gate Array) chip, and can be integrated into a semiconductor chip. The PSGC takes clock signal input, reset signal input, and pulse selector inputs (s0, s1, s2, etc.). It generates a pulse sequence output (tps).
(22) As noted above,
(23) The pulse selector inputs s1 (130) and s0 (140) determine the number of pulses present in the pulse sequence output 150. For example, the number of pulses in the pulse sequence output 150 that may be selected are 1, 2, 4, 8, etc. In one combination of the pulse selector inputs s1 (130) and s0 (140), the pulse sequence output 150 may be a continuous pulse.
(24) As noted above,
(25) The input signal line 220 is connected to 0V/ground/zero potential. However, it should be understood that this is merely illustrative, and the other input signal lines may instead be connected to 0V/ground/zero potential. For example, in some embodiments of the PSGC 200, the input signal line 225, 230 or 235 may be connected to 0V/ground/zero potential. The selection made by the multiplexer 210 between the input signals (220, 225, 230, 235) is determined by the pulse selector inputs (205/s1, 215/s0). Therefore, one of the input signals (220, 225, 230, 235) is selected and forwarded as the output signal 240 based on the pulse selector inputs (205/s1, 215/s0).
(26) The counter circuit 250 takes clock enable signal ce 255, input clock signal 260, reset signal 265 and generates output signals 270, 275, 280 and 285. The output signal 285 provides a pulse sequence output for the PSGC 200. The remaining output signals 270, 275 and 280 respectively provide input signals 235, 230, 225 for the multiplexer 210. However, it should be understood that this is merely illustrative, and the other output signals may instead be used for providing the pulse sequence output. For example, in some embodiments of the PSGC 200, the output signals 270, 275 or 280 may provide the pulse sequence output. In that case, the remaining output signals would accordingly be connected to provide input signals for the multiplexer 210. As shown in
(27) PSGC 200 uses a counter circuit 250 with clock enable signal ce as an active-high signal input. Therefore, the inverter gate 245 is required to connect the output signal 240 of the multiplexer 210 to the clock enable signal ce 255 through the inverter gate 245. However, it should be understood that this is merely illustrative, and other embodiments of PSGC 200 may not require the inverter gate 245. For example, a counter circuit 250 in an embodiment of PSGC 200 may present the clock enable signal ce as an active-low signal input, and therefore, would not require inverter gate 245.
(28) In some embodiments, the PSGC 200 divides the input clock signal 260 by half and generates the output signal 285. For example, a 20 MHz output signal 285 is generated from a 40 MHz input clock signal 260 and a 10 MHz output signal 285 is generated from a 20 MHz input clock signal 260. The reset signal 265 determines the starting of the output signal 285. In a non-limiting example, the reset signal 265 is initially active-high and when the reset signal 265 ends, the output signal 285 starts. In some embodiments, the reset signal 265 may initially be held active-low and when the reset signal 265 turns high, the output signal 285 starts.
(29) The pulse selector inputs 205 and 215 determine the number of pulses present in the output signal 285. For example, the number of pulses in the output signal 285 that may be selected are 1, 2, 4, 8, etc. In one combination of the pulse selector inputs 205 and 215, the output signal 285 may be a continuous pulse.
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(31) Referring to
(32) Referring to
(33) Referring to
(34) In a variation of the PSGC 200 in
(35) As noted above,
(36) Each of the T-FF circuits (305, 325, 355, 375) takes clock enable signal ce, input clock signal ck, reset signal res and generates output signal q. In a T-FF, if the T input is high, the T-FF changes states (i.e. toggles) whenever the clock input is strobed. However, if the T input is low, the T-FF holds the previous value. Moreover, when T is held high, the T-FF divides the input clock frequency by two. For example, if the clock frequency is 40 MHz, the output frequency obtained from the T-FF is 20 MHz. Clock signal 330 and reset signal 340, respectively, provide input clock signal ck and reset signal res for all the four T-FF circuits (305, 325, 355, 375).
(37) Enable signal 307 provides clock enable signal ce for the T-FF 305. When the enable signal 307 is high, the T-FF 305 generates an output signal 00 350. The output signal 00 350 is provided as an input to the clock enable signal ce of T-FF 325 and the AND gates 310, 320. Once T-FF 325 is enabled, T-FF 325 generates an output signal 01 352. The output signal 01 352 is provided as an input to both the AND gates 310, 320. The output 314 of the AND gate 310 is provided as an input to the clock enable signal ce of T-FF 355. Once T-FF 355 is enabled, T-FF 355 generates an output signal 02 354. The output signal 02 354 is provided as an input to the AND gate 320, which then generates an output 316. The output 316 is provided as an input to the clock enable signal ce of T-FF 375. Once T-FF 375 is enabled, T-FF 375 generates an output signal 03 356.
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(41) A multiplexer is a switch to select one of several analog or digital input signals and pass the selected input signal to a single output line. A multiplexer of 2.sup.n inputs has n select lines, which are used to select which input line to send to the output line. The multiplexer can be considered as a multiple-input, single output switch. A circuit diagram of an example of a 4-to-1 multiplexer is shown in
(42) There are many ways to implement a 4-to-1 multiplexer 1010.
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(44) As noted above, the number of pulses in the pulse sequence output generated by the PSGC 200 can be 1, 2, 4, 8, 16 etc. The number of pulses generated in the sequence is in power of two number, except for the continuous pulse sequence. Another embodiment of the PSGC is shown in
(45) As noted above,
(46) The input signal 1220 is connected to 0V/ground/zero potential. However, it should be understood that this is merely illustrative, and the other input signals may instead be connected to 0V/ground/zero potential. For example, in some embodiments of the PSGC 1200, the input signal 1225, 1230 or 1235 may be connected to 0V/ground/zero potential. The selection made by the multiplexer 1210 between the input signals (1220, 1225, 1230, 1235) is determined by the pulse selector inputs (1205/s1, 1215/s0). Therefore, one of the input signals (1220, 1225, 1230, 1235) is selected and forwarded as the output signal 1240 based on the pulse selector inputs (1205/s1, 1215/s0).
(47) The counter circuit 1250 takes clock enable signal ce 1255, input clock signal 1260, reset signal 1265 and generates output signals 1270, 1275, 1280 and 1285. The output signal 1285 provides a pulse sequence output for the PSGC 1200. All the output signals 1270, 1275, 1280 and 1285 provide input signals for the det3 and det5. In addition, the output signal 1280 provides an input signal 1225 for the multiplexer 1225. Outputs from det3 and det5 respectively are provided as input signals 1230 and 1235 for the multiplexer 1210. However, it should be understood that this is merely illustrative, and the other output signals may instead be used for providing the pulse sequence out. For example, in some embodiments of the PSGC 1200, the output signals 1270, 1275 or 1280 may provide the pulse sequence output. In that case, the remaining connections between the counter circuit 1250, det3, det5 and the multiplexer 1210 remain unchanged. As shown in
(48) The PSGC 1200 uses a counter circuit 1250 with the clock enable signal ce as an active-high signal input. Therefore, the inverter gate 1245 is required to connect the output signal 1240 of the multiplexer 1210 to the clock enable signal ce 1255 through the inverter gate 1245. However, it should be understood that this is merely illustrative, and other embodiments of the PSGC 1200 may not require the inverter gate 1245. For example, a counter circuit 1250 in an embodiment of the PSGC 1200 may present the clock enable signal ce as an active-low signal input, and therefore, would not require the inverter gate 1245.
(49) In some embodiments, the PSGC 1200 divides the input clock signal 1260 by half and generates the output signal 1285. For example, the 20 MHz output signal 1285 is generated from the 40 MHz input clock signal 1260 and the 10 MHz output signal 1285 is generated from the 20 MHz input clock signal 1260. The reset signal 1265 determines the starting of the output signal 1285. In a non-limiting example, the reset signal 1265 is initially active-high and when the reset signal 1265 ends, the output signal 1285 starts. In some embodiments, the reset signal 1265 may initially be held active-low and when the reset signal 1265 turns high, the output signal 1285 starts.
(50) The pulse selector inputs 1205 and 1215 determine the number of pulses present in the output signal 1285. For example, the number of pulses in the output signal 1285 that may be selected are 1, 3, 5, etc. In one combination of the pulse selector inputs 1205 and 1215, the output signal 1285 may be a continuous pulse. As discussed above,
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(52) Referring to
(53) The input clock signal and reset signal may be respectively connected to the input clock signal 1260 and reset signal 1265 of
(54) Similarly, the input clock signal and reset signal may be respectively connected to the input clock signal 1260 and reset signal 1265 of
(55) In a variation of the PSGC 1200 in
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(57) In
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(59) There are many applications for the embodiments of a PSGC as disclosed herein. The proposed technology is discussed herewith in detail in reference to an ultrasound probe. However, it should be understood that this is merely illustrative, and the proposed technology has other applications and uses. Non-limiting examples include a general purpose trigger signal generator, general purpose pulse burst generator, one-shot timer, strobe light etc.
(60) The ultrasound imaging system 1500 measures the reflectivity of tissue to sound waves. It can also measure velocity of moving objects, e.g. blood flow. The system 1500 provides a non-invasive imaging system without exposing a person to any radiation. The system 1500 consists of a transducer array 1565 that is used both as a transmitter and a receiver. In a transmission mode, the transmitter converts an oscillating voltage into mechanical vibrations, which transmits a series of sound pressure waves into the body. In a receiving mode, the receiver converts backscattered sound pressure waves into electrical signals. In a non-limiting example, the transducer array 1565 is comprised of an array of piezoelectric transducer elements that transmit focused energy into the body and receive the resulting reflections. The transducer array 1565 may have 32 to as many as 512 elements and may operate at frequencies from 1 MHz to 15 MHz.
(61) The ultrasound imaging system 1500 also has a transmitter/receiver (T/R) switch 1560. As noted above, the transducer array 1565 may have 32 to as many as 512 elements, but the system may have fewer transmitters and receivers than the number of available transducer elements. In these cases, a T/R switch 1560 located in the system 1500 is used as multiplexer to connect a specific transducer element to a specific transmitter/receiver pair.
(62) The ultrasound imaging system 1500 also has a Personal Computer and Field Programmable Gate Array (PC/FPGA) 1515 with one or more microprocessors that directs the operation of the entire system. The PC 1515 senses the settings of the controls and input devices, such as the keyboard, and executes the commands to control the hardware to function in the desired mode. It orchestrates the necessary setup of the transmit and receive beamformers 1550 as well as the signal processing, display, and output functions. Another important duty of the computer is to regulate and estimate the level of acoustic output in real time.
(63) The ultrasound imaging system 1500 also has a transmit clock 1520 that provides an input clock signal for various components of the system 1500. As discussed above, the PSGC 200 and 1200 both respectively receive input clock signals 260 and 1260. The transmit clock 1520 provides an input signal to the transmit signal generator 1510. Various embodiments of the transmit signal generators (i.e. PSGC 200 and 1200) are discussed above.
(64) The transmit signal generator 1510 transmits its output signal to a transmit beamformer 1550 that typically generates the necessary digital transmit signals with the proper timing and phase to produce a focused transmit signal. The ultrasound imaging system 1500 may generate complex transmit waveforms using an arbitrary waveform generator to optimize image quality. In these cases, the transmit beamformer 1550 may generate digital 8-bit to 10-bit words at rates of approximately 40 MHz to produce the required transmit waveform.
(65) A high-voltage transmit driver 1555 conditions the transmit waveform from the transmit beamformer 1550 and transmits the conditioned transmit waveform to the T/R switch 1560. As discussed above, a T/R switch 1560 located in the system 1500 connects a specific transducer element to a specific transmitter/receiver pair.
(66) The T/R switch 1560 is connected to a Low Noise Pre-Amplifier (LNA) 1545. It is desirable that the LNA 1545 have excellent noise performance and sufficient gain. The transducer element from the transducer array 1565 may be directly/indirectly connected to the LNA 1545 through a relatively long coaxial transducer cable terminated into relatively low impedance at the LNA's 1545 input. The signal received from the transducer array 1565 is amplified by the LNA 1545 and later conditioned by a variable gain amplifier 1535 and a programmable gain amplifier 1530.
(67) During the ultrasound send-receive cycle, the magnitude of reflected signal depends on the depth of penetration. The purpose of Time Gain Control (TGC) is to normalize the signal amplitude with time; compensating for depth. When the image is displayed, similar material should have similar brightness, regardless of depth and this is achieved by Linear-in-dB Gain, which means the decibel gain is a linear function of the control voltage. A time gain signal generator 1540 is connected to variable gain amplifier 1535 for TGC.
(68) The signal from the programmable gain amplifier 1505 is then transmitted to an analog to digital converter to convert the analog amplified received signal into a digital format for further processing to the PC 1515. The analog to digital converter 1505 receives an input from a receive clock 1525. Various components of the ultrasound imaging system 1500 are connected to the PC 1515 and are not discussed in detail here.
(69) Additional features and functionality of the ultrasound imaging system 1500 should generally be understood and are not discussed in further detail herein. Additionally, it should be understood that the various components described with respect to the transmit signal generator are merely illustrative. Accordingly, the ultrasound imaging system 1500 may include additional components, fewer components, alternative components, and/or the like without departing from the scope of the present disclosure.
(70) Referring now to
(71) Step 1620 includes providing a 2.sup.n-bit binary counter having a clock signal input line, a reset signal input line, a clock enable line, and 2.sup.n output lines, connecting the clock signal input line to a clock signal input, connecting the reset signal input line to a reset signal input, connecting the clock enable line to the output line of the multiplexer for providing the output of the multiplexer as an input signal for the clock enable line, one of the 2.sup.n output lines providing a sequence of pulse as an output of the transmit signal generator, and connecting each of the remaining 2.sup.n output lines of the binary counter to one of the remaining 2.sup.n input lines of the multiplexer. Step 1640 is then followed to generate a sequence of 1, 2, 4, 8, . . . n pulses. According to step 1640, the output of the transmit signal generator is providing a continuous pulse or an N pulse sequence as the output based on the selector signal and the reset signal input initiating generation of the sequence of pulses, wherein N2.sup.n and n is an integer.
(72) If an odd number (i.e. 1, 3, 5, . . . n), another integer (e.g. 6, 12, 14; numbers that are not obtained by using power of 2) or a continuous number of pulses are to be generated, then the method 1600 is followed as discussed below. The numbers discussed above are identified herein as positive integer numbers. An embodiment of method 1600 for generating a positive integer number of pulses at 1610 includes the steps of providing a 2.sup.n-to-1 multiplexer having 2.sup.n input lines, n selector lines and an output line providing an output of the multiplexer, connecting one of the 2.sup.n input lines to ground or zero potential, and connecting the n selector lines to a selector signal, the multiplexer selecting one of the 2.sup.n input lines as the output of the multiplexer based on the selector signal.
(73) At 1620, the method includes providing a 2.sup.n bit binary counter having a clock signal input line, a reset signal input line, a clock enable line, and 2.sup.n output lines, connecting the clock signal input line to a clock signal input, connecting the reset signal input line to a reset signal input, connecting the clock enable line to the output line of the multiplexer providing the output of the multiplexer as an input signal for the clock enable line, one of the 2.sup.n output lines providing a sequence of pulse as an output of the transmit signal generator, and connecting another of the 2.sup.n output lines of the binary counter to one of the 2.sup.n input lines of the multiplexer.
(74) At 1630, the method includes providing (2.sup.n-2) integer-number detector circuits and connecting each of the 2.sup.n output lines of the binary counter to each of the integer-number detector circuits as an input, each of the integer-number detector circuits having an output line connected to one of the remaining 2.sup.n input lines of the multiplexer. Integer-number detector circuits 1295, 1290 are discussed above in reference to
(75) However, it should be understood that this is merely illustrative, and other arrangements of the ultrasound imaging system and transmit signal generator relative to the above discussed various components thereof are contemplated and included within the scope of the present disclosure.
(76) The foregoing detailed description has been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit embodiments to the precise form disclosed. Many modifications and variations are possible in light of the above teaching. The described embodiments were chosen in order to explain principles and practical applications, to thereby enable others skilled in the art to best utilize various embodiments and with various modifications as are suited to the particular use contemplated. It is intended that the scope be defined by the claims appended hereto.