Topical Formulation Cures and Heals a Variety of Skin Conditions Including Ulcers, Decubitus Ulcers, Cancer, Abrasions and other Conditions and also accelerates the curing and healing of those Conditions

Abstract

A formulation consisting of Thymol Iodide, in a Lanolin, Petrolatum, Zinc Oxide, Olive Oil base is applied to a topical skin lesion. Observed also and after discussions with patients, caregivers and patient relatives, it was discovered that a certain formulation consisting of an active pharmaceutical ingredient together with a specific base formulation promoted curing and accelerated healing of a variety of conditions. This formulation was examined for its superior effectiveness leading to the discovery found within this patent application.

Such a formulation will have a drastic reduction of healthcare costs because the topical application of this formulation will effect improvement, cure and accelerated healing resulting in no need for costly operations, hospitalizations, or long-term treatment.

Claims

1. A topical formulation for the treatment of ulcerations, decubitus ulcers, skin infections, wounds, skin cancer and other skin conditions the pharmaceutical topical preparation may be in an ointment, cream, gel, liquid, emulsion, semi-solid, or other form that permits contact with the surface of the skin and it may also be used on, within, or on top of a bandage, device or dressing, said formulation containing Thymol Iodide C20H24I2O2 with a Molecular Weight of 550.23 in concentrations from 0.001% to 100.0% with the ideal concentration from 0.70% to 1.0%.

2. A formulation as described in claim 1 further comprising: A base substance that is used to contain the Thymol Iodide and provide protection for the skin, such a base substance is Lanolin providing over 30 fatty acids to the formulation said amount of Lanolin that can be used is from 0% to 100% with the ideal concentration from 30.8% to 60.8%.

3. A formulation as described in claim 1 further comprising: A base substance that is used to contain the Thymol Iodide and provide protection for the skin, such a base substance was determined to be Petrolatum which is an ointment base and provides an occlusive dressing over the skin, said amount of Petrolatum that can be used is from 0% to 100% with the ideal concentration from 24.0% to 54%.

4. A formulation as described in claim 1 further comprising: A protective, astringent, antiseptic, substance that offers some lethality to cancerous cells and offers protection for the skin, such a substance was founded to be Zinc Oxide, said amount of Zinc Oxide that can be used is from 0% to 100% with the ideal concentration from 4% to 14%.

5. A formulation as described in claim 1 further comprising: An emollient base substance that is used to contain the Thymol Iodide, such an emollient base substance was determined to be Olive Oil, said Olive Oil in addition to being an emollient base, provides fatty acids to the formulation which are converted into Acetyl Coenzyme A and effect an enhanced healing of ulcerations, skin infections, wounds, skin cancer and other skin conditions when applied to the skin with said amount of Olive Oil that can be used from 0% to 100% with the ideal concentration from 0% to 10.7%.

6. A formulation consisting of Thymol Iodide, Lanolin, Petrolatum, Zinc Oxide and Olive Oil prepared as a pharmaceutical topical preparation in an ointment, cream, gel, liquid, emulsion, semi-solid, or other form that permits contact with the surface of the skin and which may also be used on, within, or on top of a bandage, device or dressing.

7. A formulation as described in claim 6 further comprising: Thymol Iodide 0.85%, Lanolin 45.8%, Petrolatum 39.0%, Zinc Oxide 9.0%, Olive Oil 5.35% prepared as a pharmaceutical topical preparation in an ointment, cream, gel, liquid, emulsion, semi-solid, or other form that permits contact with the surface of the skin and which may also be used on, within, or on top of a bandage, device or dressing.

8. A formulation consisting of at least one antimicrobial/anti-infective agent that is safe and effective for the treatment of ulcerations, skin infections, wounds, cancer and other skin conditions and a pharmaceutical base that provides fatty acids and a protective, astringent, antiseptic, substance that is preferably lethal to cancerous cells and offers protection for the skin.

9. A formulation as described in claim 8 prepared as a pharmaceutical topical preparation in an ointment, cream, gel, liquid, emulsion, semi-solid, or other form that permits contact with the surface of the skin and which may also be used on, within, or on top of a bandage, device or dressing.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0024] This invention will now be described in detail.

[0025] The pharmaceutical topical preparation may be in an ointment, cream, gel, liquid, emulsion, semi-solid, or other form that permits contact with the surface of the skin. It may also be used on, within, or on top of a bandage, device or dressing. This invention consists of the following ingredients for the purposes so presented: [0026] 1At least one antimicrobial/anti-infective agent that is safe and effective for the treatment of ulcerations, skin infections, wounds, cancer and other skin conditions. Such an agent was discovered to be Thymol Iodide C.sub.20H.sub.24I.sub.2O.sub.2 with a Molecular Weight of 550.23 in concentrations from 0.001% to 100.0% with the ideal concentration from 0.70% to 1.0%. Thymol Iodide has for its main purpose to provide an antiseptic, antibacterial, antifungal and other antimicrobial/antiviral environment. This environment is paramount to the regrowth of tissue and protection of the wound from a contaminated environment. Thymol Iodide also promotes the healing of ulcerations, wounds, and skin infection. Thymol iodide has also been used internally for healing cancerous pleural effusions but the inventiveness here is that it heals cancerous lesions externally on the skin as well when left in contact with the lesion. [0027] 2A base substance that is used to contain the Thymol Iodide and provide protection for the skin. Such a base substance was determined to be Lanolin. In addition to being an ointment base, lanolin provides over 30 fatty acids which are converted into Acetyl Coenzyme A and effect an enhanced healing of the of ulcerations, skin infections, wounds, skin cancer and other skin conditions. The lanolin is also able to retain and absorb water from the environment and within the skin. The amount of Lanolin that can be used is from 0% to 100% with the ideal concentration from 30.8% to 60.8%. If lanolin is not used as a portion of the base, a replacement base preferably contains a fatty acid. [0028] 3A base substance that Is used to contain the Thymol Iodide and provide protection for the skin. Such a base substance was determined to be Petrolatum. In addition to being an ointment base, Petrolatum provides an occlusive dressing over the skin. The amount of Petrolatum that can be used is from 0% to 100% with the ideal concentration from 24.0% to 54%. If petrolatum is not used as a portion of the base, a replacement base preferably provides an occlusive dressing to the skin. [0029] 4A protective, astringent, antiseptic, substance that is preferably lethal to cancerous cells and offers protection for the skin. It was founded that Zinc Oxide is such a substance. The amount of Zinc Oxide that can be used is from 0% to 100% with the ideal concentration from 4% to 14%. If zinc oxide is not used the replacement substance should provide protective, astringent, antiseptic, and be lethal to cancer cells. [0030] 5An emollient base substance that is used to contain the Thymol Iodide. Such an emollient base substance was determined to be Olive Oil. In addition to being an emollient base, Olive Oil provides fatty acids which are converted into Acetyl Coenzyme A and effect an enhanced healing of ulcerations, skin infections, wounds, skin cancer and other skin conditions. The amount of Olive Oil that can be used is from 0% to 100% with the ideal concentration from 0% to 10.7%. If Olive Oil is not used as a portion of the base, a replacement emollient base substance preferably contains fatty acids. [0031] 6The complete finished product may be prepared by any suitable method or with any suitable equipment as know by those familiar with the art of Pharmacy and Manufacturing Pharmacy. The completed finished product may be prepared with use of heat or at room temperature without any heat. [0032] 7To produce a batch of the finished product using heat, the following procedure was used: Heat a supply of Lanolin to 140 F. Heat a separate supply of Petrolatum to 137 F. Charge a 5 Liter stainless-steel mixing bowl with 170 G of Thymol Iodide. Add 1,070 G Olive Oil to the Thymol Iodide and mix high speed 3 minutes or until uniformly dispersed. Charge 7,800 G of heated Petrolatum into stainless-steel mixer bowl of Thoroughbred Mixer. Charge 1,800 G of Zinc Oxide into the Thoroughbred Mixer. Mix for 5 minutes or until uniformly dispersed. Add 9,160 G of heated Lanolin to the Thoroughbred Mixer. Mix for 5 minutes or until uniform. Add the Thymol Iodide-Olive Oil mix in the 5 Liter mixer bowl to the blend in the Thoroughbred Mixer. Mix for 5 minutes or until uniform. Allow to cool, transfer batch to filling machine and fill into final container. [0033] 8To produce a batch of the finished product without using heat, the following procedure was used: Charge a 5 Liter stainless-steel mixing bowl with 170 G of Thymol Iodide. Add 1,070 G Olive Oil to the Thymol Iodide and mix high speed 3 minutes or until uniformly dispersed. Charge 7,800 G of Petrolatum into stainless-steel mixer bowl of Thoroughbred Mixer. Charge 1,800 G of Zinc Oxide into the Thoroughbred Mixer. Mix for 5 minutes or until uniformly dispersed. Add 9,160 G of Lanolin to the Thoroughbred Mixer. Mix for 5 minutes or until uniform. Add the Thymol Iodide-Olive Oil mix in the 5 Liter mixer bowl to the blend in the Thoroughbred Mixer. Mix for 5 minutes or until uniform. Transfer batch to filling machine and fill into final container.