CANNABINOID-INFUSED POST-OPERATIVE DENTAL DRESSING
20200163746 ยท 2020-05-28
Inventors
Cpc classification
A61F7/02
HUMAN NECESSITIES
A61F7/12
HUMAN NECESSITIES
A61K9/009
HUMAN NECESSITIES
A61F2007/108
HUMAN NECESSITIES
A61C19/063
HUMAN NECESSITIES
A61L2300/30
HUMAN NECESSITIES
A61K36/9066
HUMAN NECESSITIES
International classification
A61K36/9066
HUMAN NECESSITIES
A61F7/02
HUMAN NECESSITIES
A61K9/00
HUMAN NECESSITIES
A61L15/42
HUMAN NECESSITIES
A61F7/12
HUMAN NECESSITIES
A61K9/70
HUMAN NECESSITIES
Abstract
A dental dressing to promote hemostasis, reduce inflammation, alleviate pain, and lower incidence of infection associated with dental surgical procedures. The dressing comprises a three-dimensional absorbent matrix to assist in the removal of exudate associated with iatrogenic trauma, and embedded cannabinoid-infused therapeutic phytoconstituents to provide substantially localized therapy to the surgical site. The cannabinoid-infused therapeutic phytoconstituents are substantially contained within a porous dressing pouch shapeable to substantially engage the iatrogenic trauma while fitting generally over and about the surgical site. At least part of the dressing matrix substantially conforms to the surgical site, thereby engaging the therapeutic phytoconstituents intimately with the iatrogenic trauma.
Claims
1. A dental dressing pouch for an oral surgical site, which comprises: a three-dimensional absorbent matrix including a porous dressing material to assist in the removal of exudate associated with iatrogenic trauma, and; at least one cannabinoid-infused therapeutic phytoconstituent within said porous dressing material to provide substantially localized therapy to a surgical site, wherein said at least one cannabinoid-infused therapeutic phytoconstituent contained within said porous dressing material form a pliable pouch shapeable to substantially engage an iatrogenic trauma fitting generally over and about the surgical site.
2. The dressing pouch of claim 1, wherein at least part of said three-dimensional dressing matrix substantially conforms to the surgical site, thereby engaging said at least one cannabinoid-infused therapeutic phytoconstituent intimately with the iatrogenic trauma.
3. The dressing pouch of claim 1, wherein said dressing pouch is one of a filter-paper, a muslin, a silk, a cotton gauze, a tulle, a cotton, and/or a combination thereof.
4. The dressing pouch of claim 1, wherein said dressing pouch includes one of a hydrogel, an alginate, a hydrofibre, a chitosan, and/or a combination thereof.
5. The dressing pouch of claim 1, which further includes a tea and turmeric mixed with said at least one cannabinoid within said porous dressing material.
6. The dressing pouch of claim 5, wherein said mixture is substantially non-migrating.
7. The dressing pouch of claim 6, wherein said porous dressing material is formed in a generally rectangular-shaped porous dressing pouch.
8. The dressing pouch of claim 6, wherein said porous dressing material is formed in a generally circular-shaped porous dressing pouch.
9. The dressing pouch of claim 6, wherein said porous dressing material is formed in a generally U-shaped porous dressing pouch to engage one or more exposed alveoli.
10. The dressing pouch of claim 6, wherein said porous dressing material is formed in substantially U-shaped cross section and is elongated to engage a plurality of adjacent exposed alveoli.
11. The dressing pouch of claim 6, wherein said porous dressing material is formed wherein said porous dressing pouch is substantially H-shaped to engage substantially aligned maxillary and mandibular exposed alveoli.
12. The dressing pouch of claim 6, wherein said porous dressing pouch includes a substantially H-shaped cross section and is elongated to engage a plurality of adjacent, substantially aligned, exposed maxillary and mandibular alveoli.
13. The dressing pouch of claim 1, wherein said porous dressing material further includes a moisture-liberating element.
14. The dressing pouch of claim 1, wherein said porous dressing material includes a moisture-liberating element having at least one of a hydrogel, hydrocolloid, and hydrofibre.
15. The dressing pouch of claim 1, wherein said porous dressing material includes a topical agent element.
16. The dressing pouch of claim 15, wherein said topical agent element includes clove oil (eugenol) infused with cannabidiol.
17. The dressing pouch of claim 16, wherein said topical agent element includes one of benzocaine, iodophorm, soluble aspirin, zinc oxide, and/or a combination thereof.
18. The dressing pouch of claim 1, wherein said cannabinoid-infused therapeutic phytoconstituent further includes a thermally active gel-like substance.
19. The dressing pouch of claim 15, wherein said thermally active gel-like substance provides localized cooling as a therapeutic benefit.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0020] The following example embodiments are representative of exemplar techniques and structures designed to carry out the objects of the present general inventive concept, but the present general inventive concept is not limited to these example embodiments. In the accompanying drawings and illustrations, the sizes and relative sizes, shapes, and qualities of lines, entities, and regions may be exaggerated for clarity. A wide variety of additional embodiments will be more readily understood and appreciated through the following detailed description of the example embodiments, with reference to the accompanying drawings in which:
[0021]
[0022]
[0023]
[0024]
[0025]
[0026]
[0027]
[0028]
[0029]
[0030]
[0031]
[0032]
[0033]
[0034]
[0035]
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
[0036] Reference will now be made to various example embodiments of the present inventive concept, examples of which are illustrated in the accompanying drawings and illustrations. The exemplar embodiments are described herein in order to explain the present general inventive concept by referring to the figures. The following detailed description is provided to clarify the methods, apparatuses, and/or systems described herein. Accordingly, various changes, modifications, and equivalents of the methods, apparatuses, and/or systems described herein will be apparent to those of ordinary skill in the art.
[0037] A dental wound dressing 100 for dental surgical procedures, in accordance with various embodiments of the present general inventive concept, is shown generally in
[0038] A dental dressing 100 for treating dental surgical procedures includes an exterior dressing pouch 101. The dressing pouch 101 can be a comprised of dressing material that adapts to various spatial requirements. For instance, one suitable dressing pouch 101 material is cotton gauze. Cotton gauze can be shaped, configured, and adjusted to conform to a given space. Moreover, cotton gauze is readily adaptable to the particular morphology and topology concerns of an exposed tooth socket, for example. Also important, gauze provides an appropriate medium to absorb blood and other exudate from the wound site. One skilled in the art will understand that the present general inventive concept is, of course, not limited to using gauze. For example, filter-paper, muslin, silk, cotton swabs, tulle, and the like, or any combination thereof, can also be utilized to achieve excellent clinical efficacy. In addition, dressing pouches containing topical agents and bio-ingredients such as, for example, hydrogel, alginate, hydrofibre, collagen, chitosan, or any combination thereof, can also be utilized. Other suitable dressing pouches will be apparent to those skilled in the art, and may be used without deviating from the scope or spirit of the present general inventive concept.
[0039] Contained substantially within the dressing pouch 101, is a cannabinoid-infused phytotherapeutic matrix 102. In the illustrated embodiment, the phytotherapeutic matrix 102 is substantially comprised of tea blends, turmeric and cannabinoids. More specifically, in the illustrated embodiment, the phytotherapeutic matrix 102 is substantially comprised of a substantially non-migrating mixture. Otherwise stated, the phytotherapeutic matrix 102 in the present embodiment is semi-rigid and effective at substantially retaining its shape under pressure.
[0040] Additionally, in some embodiments of the general present inventive concept, the phytotherapeutic matrix 102 can include a thermally active gel-like substance. Otherwise stated, the matrix 102 can substantially retain its temperature after introduction into hot or cold environments and subsequent removal therefrom. For example, the dressing can be placed in a refrigerator or freezer until cooled to a desired temperature. Upon removal from the cold environment, the dressing will substantially retain its cold temperature and subsequently provide cooling of the surgical site when placed within the oral cavity.
[0041] One skilled in the art will understand that the present general inventive concept is not limited to a phytotherapeutic matrix 102 that includes gel. On the contrary, other substances with similar properties can comprise the phytotherapeutic matrix 102. For instance, ammonium nitrate and water contained within a common housing member can combine to produce an endothermic reaction resulting in a cold product. Similarly, cannabinoid-infused clove oil can also be mixed into the matrix and stored in a cold environment. Of course, in order to create a phytotherapeutic matrix 102, the above-mentioned ingredients will have to be contained in a porous dressing pouch that can be readily inserted into an oral cavity and engage a surgical site, while also substantially fitting between contiguous teeth. Further, in some embodiments, the porous dressing pouch can be relatively pliable, so as to prevent damage to teeth exerting pressure on the dental dressing 100. One skilled in the art will recognize that several polymer-based materials can also be utilized to create the porous dressing pouch that is adaptable for insertion into an oral cavity. One skilled in the art will also understand, however, that the present general inventive concept is not limited to the above-mentioned substances. Other substances capable of retaining a cold temperature and being contained within a porous dressing pouch can also be used without departing from the scope or spirit of the present general inventive concept.
[0042]
[0043] When engaging an exposed tooth socket, the phytotherapeutic matrix 102 can be oriented in such a way that it substantially covers and surrounds the exposed tooth socket while also fitting between contiguous teeth. More specifically, when engaging an exposed tooth socket, the cover portions of the present example embodiments can sit on top of, or be disposed directly beneath, one or more exposed tooth sockets, while the two tapered arm members laterally flank one or more exposed tooth sockets on opposing sides of the oral epithelium. Otherwise stated, the phytotherapeutic matrix 102 can superpose the exposed tooth socket as well as engage both sides of the oral epithelium and gingival tissue proximate the exposed socket, with one arm member engaging the facial surface of the proximate gum tissue, and the other arm member engaging the lingual surface of the proximate gum tissue.
[0044] The primary difference between the embodiment illustrated in
[0045]
[0046] Each exposed tooth socket 401, and for that matter any iatrogenic trauma, contains particular morphological and topological concerns. For example, an exposed tooth socket 401 generally contains a cavity, into which the root of a tooth is generally disposed and secured to the alveolar (jaw) bone with periodontal ligaments. Further, the gingival tissue immediately abutting and surrounding the cavity has distinct contours and shapes. For instance, the marginal and attached gingiva contain depressions, grooves, and indentations. In this regard, the dressing 100 can substantially conform to the topology and morphology of the exposed tooth socket 401 and proximate gingival and epithelial tissue, and can be compressed to apply appropriate pressure for promoting hemostasis. The dressing pouch 101 can also be compressed in such a way that part of it actually extends into the cavity in the open socket 401. The pressure applied by the dressing pouch 101 substantially assists the wound site in achieving hemostasis.
[0047] Additionally, the dressing pouch 101 can be compressed against and into the exposed tooth socket 401 to fully engage the cannabinoid-infused phytotherapeutic matrix 102 with the exposed tooth socket 401. The phytotherapeutic matrix 102 substantially covers and encompasses the exposed tooth socket and proximate tissue to relieve pain and reduce inflammation, while fitting substantially between contiguous teeth. The therapeutic effectiveness of the phytotherapeutic matrix 102 is significantly influenced by its proximity to the exposed tooth socket and proximate soft tissue. The proximity of the phytotherapeutic matrix 102 to the exposed tooth socket is directly affected by the amount and degree of compression of the dressing pouch 101 between the phytotherapeutic matrix 102 and the exposed socket.
[0048] Referring now to
[0049]
[0050] In the embodiments illustrated in
[0051] In the embodiments depicted in
[0052] In the illustrated embodiments, the moisture-liberating elements 801 are disposed between the topical agent elements 901 and the phytotherapeutic matrix 102, all embedded and contained substantially within the dressing pouch 101. Most topical agents envisioned to be included in the elements 901 are water soluble. Therefore, disposing the moisture-liberating element 801 between the topical agent and the phytotherapeutic matrix 102 will ensure that the topical agent element 901 becomes moist, thus facilitating topical application to the surgical site or exposed tooth socket 401. Furthermore, the therapeutic effectiveness of the topical agent element 901 is optimized by disposing it proximate to the wound site. However, one skilled in the art will understand that the relative disposition of the moisture-liberating elements 801 and the topical agent elements 901 described herein is non-limiting.
[0053] In the embodiments illustrated in
[0054]
[0055]
[0056]
[0057]
[0058]
[0059] In some instances, a patient has both rows of teeth extracted. Otherwise stated, it is possible to have both maxillary 1101 and mandibular 1102 full row extractions at substantially the same time. Therefore, in some embodiments of the present general inventive concept, two dental dressings 100 having U-shaped cross-sections can each independently engage the maxillary row 1101 and mandibular row 1102. In this embodiment, because two distinct dental dressings 100 are being used, a straw or other feeding apparatus can be inserted into the oral cavity between the two dental dressings 100. On the other hand, in other embodiments, one dental dressing having an H-shaped cross section can engage both the maxillary and mandibular row of exposed tooth sockets. However, in this embodiment, a straw or like device will not be able to be inserted into the patient's oral cavity because of the occluding dental dressing engaging both the upper and lower rows of tooth sockets (or surgical site).
[0060] The embodiments described herein provide a dental dressing 100 for an iatrogenic trauma or (extended) surgical site including a phytotherapeutic matrix 102 embedded and contained substantially within a dressing pouch 101. The dressing pouch 101 can be adaptable to conform to various shapes and contours as required by the particular anatomy and underlying topology. The phytotherapeutic matrix 102 can be sized and shaped to engage an exposed tooth socket and flank opposing sides of the oral epithelium, while fitting substantially between contiguous teeth. In some embodiments, the cannabinoid-infused phytotherapeutic matrix 102 includes a semi-rigid, substantially non-migrating thermally active gel-like material contained within a housing member. Following a tooth extraction, for example, patients can place the dental dressing 100 in a cold environment so that the dressing becomes cold. Subsequently, the patient can remove the dental dressing 100 from the cold environment and introduce it into their oral cavity. The dressing pouch 101 can be compressed into the exposed socket, thereby engaging the embedded phytotherapeutic matrix 102 with the exposed tooth socket. The dressing pouch 101, and the applied pressure, will help absorb exudate and promote vasoconstriction, while the cold phytotherapeutic matrix 102 will reduce inflammation, promote vasoconstriction, and relieve pain.
[0061] In other embodiments, the phytotherapeutic matrix 102 includes ammonium nitrate and water substantially contained within a polymer-based housing member. Patients/caregivers can cause the phytotherapeutic matrix 102 to become cold by effectuating an endothermic reaction with the ammonium nitrate and water, by, for example, shaking the matrix 102 or inserting water into a housing member that already contains ammonium nitrate. Similarly, after the endothermic reaction takes place to produce a cold phytotherapeutic matrix 102, the dental dressing 100 can be placed within the patient's oral cavity in the same manner described herein above.
[0062] In some embodiments of the dental dressing 100, the phytotherapeutic matrix 102 is shaped substantially like a U, and sized to engage, for example, one exposed tooth socket. In other embodiments, the phytotherapeutic matrix 102 is shaped generally like a U, but with tapered side members angularly extending from a cover portion. In yet other embodiments, the phytotherapeutic matrix 102 has a U-shaped cross section, but is elongated to substantially engage an extended surgical site, for example, a plurality of adjacent, exposed tooth sockets. In yet other embodiments, the phytotherapeutic matrix 102 is shaped generally like an H, with perpendicular or angled, tapered or non-tapered side members extending from a cover portion, to substantially engage substantially aligned maxillary 1101 and mandibular 1102 exposed tooth sockets. In other embodiments, the phytotherapeutic matrix 102 has an H-shaped cross section, but is elongated to substantially engage an extended surgical site, for example, a plurality of adjacent, substantially aligned maxillary and mandibular exposed tooth sockets.
[0063] In some embodiments, the dental dressing 100 includes a hydrogel element 801 embedded and contained substantially within the dressing pouch 101. In other embodiments, the dental dressing 100 includes an element 801 substantially comprised of hydrogel, hydrocolloid, hydrofibre, and/or any combination thereof. One skilled in the art will recognize that other, moisture-liberating elements can also be used without deviating from the scope or spirit of the general present inventive concept. These moisture-liberating elements 801 are particularly applicable in instances where a dry socket evolves after tooth extraction.
[0064] In some embodiments, the dental dressing 100 includes an active topical agent element 901. In other embodiments, the active topical agent element 901 includes medications like eugenol, benzocaine, iodophorm, soluble aspirin, zinc oxide, or any combination thereof. One skilled in the art will recognize that the present general inventive concept is not limited to the use of the specific substances described herein, but can also encompass other, topical agents that can be included in the element 901 for topical application to an exposed tooth socket.
[0065] Numerous variations, modifications, and additional embodiments are possible, and accordingly, all such variations, modifications, and embodiments are to be regarded as being within the spirit and scope of the present inventive concept. For example, regardless of the content of any portion of this application, unless clearly specified to the contrary, there is no requirement for the inclusion in any claim herein or of any application claiming priority hereto of any particular described or illustrated activity or element, any particular sequence of such activities, or any particular interrelationship of such elements. Moreover, any activity can be repeated, any activity can be performed by multiple entities, and/or any element can be duplicated.
[0066] The above described embodiments are set forth by way of example and are not for the purpose of limiting the scope of the present inventive concept. It will be readily apparent that obvious modifications, derivations and variations can be made to the embodiments without departing from the scope of the present inventive concept. Accordingly, the claims appended hereto should be read in their full scope including any such modifications, derivations and variations.