Trace element solution

Abstract

A trace element solution comprises at least the following metals zinc directly and/or indirectly from Zn-EDTA and/or Zn oxide; manganese directly and/or indirectly from Mn-EDTA and/or manganese carbonate; copper directly and/or indirectly from Cu-EDTA and/or copper oxide and/or copper sulphate, and/or copper carbonate; selenium derived directly and/or indirectly from Na.sub.2SeO.sub.4 and/or Na.sub.2SeO.sub.3. The metals are present in a solution of water, chlorocresol and/or benzyl alcohol, at a concentration of metals of at least 95 mg/ml. The pH of the trace element solution adjusted by means of 30% NaOH in an injectable trace element solution that is visually stable.

Claims

1. A trace element solution, which comprises at least the following metals: (a) zinc directly and/or indirectly from Zn-EDTA and/or Zn oxide, wherein zinc is present in at least 65 mg/ml zinc directly and/or indirectly from Zn-EDTA and/or Zn oxide; (b) manganese directly and/or indirectly from Mn-EDTA and/or manganese carbonate; (c) copper directly and/or indirectly from Cu-EDTA and/or copper oxide and/or copper sulphate, and/or copper carbonate; and (d) selenium derived directly and/or indirectly from Na.sub.2SeO.sub.4 and/or Na.sub.2SeO.sub.3, wherein the metals are present in a solution of water, chlorocresol and/or benzyl alcohol, at a concentration of metals of at least 95 mg/ml; wherein the pH of the trace element solution adjusted by means of 30% NaOH in an injectable trace element solution that is visually stable; and wherein a ratio of zinc to manganese is at least 6.5:1.

2. The trace element solution of claim 1, wherein manganese is present in at least 10 mg/ml manganese directly and/or indirectly from Mn-EDTA and/or manganese carbonate.

3. The trace element solution of claim 1, wherein copper is present in at least 15 mg/ml copper directly and/or indirectly from Cu-EDTA and/or copper oxide and/or copper sulphate, and/or copper carbonate.

4. The trace element solution of claim 1, wherein selenium is present in at least 5 mg/ml selenium derived directly and/or indirectly from Na.sub.2SeO.sub.4 and/or Na.sub.2SeO.sub.3.

5. The trace element solution of claim 1, wherein a ratio of zinc to copper is at least 4:1.

6. The trace element solution of claim 1, wherein a ratio of zinc to selenium is at least 13:1.

7. The trace element solution of claim 1, further comprises iodine.

8. The trace element solution of claim 7, wherein iodine is present in 50 mg/ml.

9. The trace element solution of claim 7, wherein the iodine is derived from potassium iodide.

Description

EXAMPLE 1

(1) Specifications

(2) TABLE-US-00001 g/L Zinc 65 Manganese 10 Copper 15 Selenium 5 Iodine 50 (A) 1. Purified water 637.255 2. Mn-EDTA (14.12%) 70.83 3. Zn-EDTA (16.36%) 397.31 4. Cu-EDTA (15.98%) 93.89 5. Mix with silverson until solution is clear (B) 1. pH: Record pH 2. heat to 50° C. Add chlorocresol and mix 1.1 until dissolved (±10 mins) 3. pH: Record pH OR 1. pH: record pH 2. Add benzyl alcohol and mix until 10.46 dissolved (±10 mins) 3. pH: Record pH 4. Cool to <25° C. and add Na.sub.2SeO.sub.4 or 11.96/10.95 Na.sub.2SeO.sub.3 5. pH: 6. Potassium Iodide 65.407 (C) 1. Adjust pH to 7/7.5/8 with 30% NaOH 2. SG: 1.275-1.35 3. Filter solution

EXAMPLE 2

(3) Specifications

(4) TABLE-US-00002 g/L Zinc 65 Manganese 10 Copper 15 Selenium 5 (A) 6. Purified water 637.255 7. Mn-EDTA (14.12%) 70.83 8. Zn-EDTA (16.36%) 397.31 9. Cu-EDTA (15.98%) 93.89 10. Mix with silverson until solution is clear (B) 4. pH: record 5. Heat to 50° C. and add chlorocresol and mix 1.1 until dissolved (±10 mins) 6. pH: Record OR 7. pH: 8. Add benzyl alcohol and mix until dissolved 10.46 (±10 mins) 9. pH: 10. Cool to <25° C. and add Na.sub.2SeO.sub.4 or 11.96/10.95 Na.sub.2SeO.sub.3 11. pH: (C) 1. Adjust pH to 7/7.5/8 with 30% NaOH 2. SG: 1.275-1.35 3. Filter solution

EXAMPLE 3

(5) Specifications

(6) TABLE-US-00003 g/L Zinc 70 Manganese 10 Copper 15 Selenium 5 Iodine 50 (A) 11. Purified water 637.255 12. Mn-EDTA (14.12%) 70.83 13. Zn-EDTA (16.36%) 427.87 14. Cu-EDTA (15.98%) 93.89 15. Mix with silverson until solution is clear (B) 7. pH: Record pH 8. Heat to 50° C. and Add chlorocresol and 1.1 mix until dissolved (±10 mins) 9. pH: Record pH OR 12. pH : 13. Add benzyl alcohol and mix until 10.46 dissolved (±10 mins) 14. pH : 15. Cool to <20° C. and add Na.sub.2SeO.sub.4 or 11.96/10.95 Na.sub.2SeO.sub.3 16. pH : 17. Potassium Iodide 65.407 (C) 1. Adjust pH to 7/7.5/8 with 30% NaOH 2. SG: 1.275-1.35 3. Filter solution

EXAMPLE 4

(7) TABLE-US-00004 g/L Zinc 70 Manganese 10 Copper 15 Selenium 5 (A) 16. Purified water 637.255 17. Mn-EDTA (14.12%) 70.83 18. Zn-EDTA (16.36%) 427.87 19. Cu-EDTA (15.98%) 93.89 20. Mix with silverson until solution is clear (B) 10. pH : Record pH 11. Heat to 50° C. and Add chlorocresol and 1.1 mix until dissolved (±10 mins) 12. pH : Record pH OR 18. pH : 19. Add benzyl alcohol and mix until dissolved 10.46 (±10 mins) 20. pH : 21.Cool to <20° C. and add Na.sub.2SeO.sub.4 or 11.96/10.95 Na.sub.2SeO.sub.3 22. pH : (C) 1. Adjust pH to 7/7.5/8 with 30% NaOH 2. SG: 1.275-1.35 3. Filter solution