Transfer Device for Fluid Transmission

Abstract

A transfer device 2 for fluid transmission from a storage bottle 1 to a receiving unit, comprising at least one housing with a housing insert or inset which comprises at least one transfer needle 8, 9 and a needle protector. To ensure sufficient safety for the personnel, a new transfer device 2 is suggested which is suited for screwing on a disposable syringe 3 and may be directly connected to a storage bottle 1. Here, the transfer device 2 consists of only few elements which on the one hand ensure a reliable function and on the other hand prevent any contact with toxic medicine. To this end, the housing has a tubular design and has at one end an open cylinder section with at least one locking unit for a storage bottle 1, and at the other end an opening for a housing insert.

Claims

1. A transfer device (2) for fluid transmission, in particular of toxic medicine, from a storage bottle (1) to a receiving unit, comprising at least one housing (25) with a housing insert or inset (40) comprising at least one transfer needle (8, 9) and a needle protector, characterized in that the housing (25) having a tubular design and comprising, at one end, an open cylinder section with at least one locking unit for a storage bottle (1), and at the other end an opening (50) for the housing insert or inset (40).

2. A transfer device (2) according to claim 1, wherein the housing insert or inset (40) consists of a pot-like intermediate part (28) which comprises, in the axial direction towards the radial bottom surface, one integrally moulded first and second pins (6, 27, 31) each on both sides.

3. A transfer device (2) according to claim 1, wherein a through bore extends through the pins (6, 27, 31).

4. A transfer device (2) according to claim 1, wherein a first pin (6, 27, 31) protruding from the bottom surface to the outside is provided for shifting on a needle protector, and/or a second pin (6, 27, 31) protruding from the bottom surface is provided within the pot-like indentation for centring.

5. A transfer device (2) according to claim 1, wherein the pot-like indentation is closable with a lid (35) to which a third pin (6, 27, 31) with a Luer-Lock thread (4) is integrally moulded.

6. A transfer device (2) according to claim 1, wherein the intermediate part (28) and the lid (35) may be connected or welded by laser welding to each other via locking elements.

7. A transfer device (2) according to claim 1, wherein a valve disk (45), a valve seal, a filter frame (47) with openings (53), a hydrophobic membrane filter and/or an activated-carbon filter are located in the pot-like indentation.

8. A transfer device (2) according to claim 1, wherein the needle protector consists of an elastic material which comprises at one end a bore (26, 29, 32, 41, 42) which is provided for receiving a second pin (6, 27, 31) of the bottom surface and is has an accordion-like shape.

9. A transfer device (2) according to claim 1, wherein the needle protector comprises a disc and a cylindrical elevation (23) on the side facing outwards.

10. A transfer device (2) according to claim 1, wherein the elevation (23) comprises a centrical surface which may be punctured by at least one needle, and/or the centrical surface comes to lie against a seal (63) of the storage bottle (1).

11. A transfer device (2) according to claim 1, wherein the needle protector is, when the transfer device (2) is placed onto a storage bottle (1), compressed in the axial direction, and thereby the needles come out of the centrical surface.

12. A transfer device (2) according to claim 1, wherein the needle protector is configured to receive two transfer needles (8, 9), one transfer needle (8, 9) being provided for sucking the liquid out of the storage bottle (1), and a second transfer needle (8, 9) being provided for air supply, and/or the second transfer needle (8, 9) forms an air duct which is connected to the outside air via a filter arrangement.

13. A transfer device (2) according to claim 1, wherein the air duct is sealed by a valve seal which opens when air enters and remains in a closed position in case of any overpressure in the storage bottle (1).

14. A transfer device (2) according to claim 1, wherein the valve seal is equipped with a one-sided edge swelling, or a filter frame (47) or a filter disk is equipped with an edge-sided bulge (51).

15. A transfer device (2) according to claim 1, wherein the cylinder section comprises, by two diametrically opposed recesses each, a tube wall section formed between the recesses.

16. A transfer device (2) according to claim 1, wherein the tube wall section is equipped at one end with a locking hook (36) and comprises at the other end a pressing surface (20, 21) protruding from the tube wall section, and/or the tube wall section is only connected with the housing (25) via a web (38) in an elastically movable manner.

17. A transfer device according to claim 1 in which the transfer needle (8, 9) is protected by said needle protector formed of an elastic material, wherein the needle protector is at one end placed on the housing inset and at the other end comprises an annular rubber seal (24) which is provided for abutment against a rubber seal of the storage bottle (1).

18. A transfer device according to claim 17 in which the needle protector is accordion-like.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0034] In the drawings:

[0035] FIG. 1 shows a storage bottle with a transfer device and a disposable syringe placed thereon in a perspective view,

[0036] FIG. 2 shows the representation of FIG. 1 in a perspective sectional view,

[0037] FIG. 3 shows the transfer device in an enlarged representation with the storage bottle and the disposable syringe in a perspective sectional view,

[0038] FIG. 4 shows the transfer device in a perspective view,

[0039] FIG. 5 shows the transfer device in a perspective sectional view,

[0040] FIG. 6 shows the individual parts of the transfer device in a perspective exploded view,

[0041] FIG. 7 shows the transfer device in the region of the intermediate part in an enlarged sectional side view,

[0042] FIG. 8 shows the individual parts of the filter unit in a perspective exploded view,

[0043] FIG. 9 shows a transfer device with a disposable syringe and an infusion bag before the transfer device is placed in a perspective view, and

[0044] FIG. 10 shows the representation according to FIG. 9 after the transfer device has been placed in a perspective view.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0045] FIG. 1 shows a storage bottle 1 with a transfer device 2 and a disposable syringe 3 placed thereon in a perspective view. The storage bottle 1 consists of a cylindrical glass vessel which is first rounded in the upper region and passes over into a tapering neck of the bottle. The transfer device 2 is placed on this tapering neck of the bottle, wherein furthermore the disposable syringe 3 is screwed on a threaded section of the transfer device 2.

[0046] FIG. 2 shows the arrangement according to FIG. 1 consisting of a storage bottle 1, a transfer device 2, and a disposable syringe 3 in a perspective view. The disposable syringe 3 is here connected to a pin 6 of the transfer device 2 via a Luer-Lock thread 4 so that, when the piston 7 is pulled out, the liquid may be sucked out of the storage bottle 1 via a transfer needle 8. Simultaneously, via a transfer needle 9 and a provided filter unit 10, air from outside may get, via the filter unit 10 and the transfer needle 9, into the interior of the storage bottle 2 to cause pressure compensation. The two transfer needles 8, 9 are here surrounded by a protective covering 11 within the transfer device 2 and come out of a front face of the protective covering 11 when the transfer device 2 is being placed onto the storage bottle 1 due to the fact that the protective covering 11 having an accordion-like shape is simultaneously compressed when it is placed on. If the transfer device 2 is removed from the storage bottle 1 and thus the front face of the protective covering is no longer in contact with the rubber seal of the storage bottle 1, the protective covering will slide back into its original position so that the two transfer needles 8, 9 are completely enclosed by the protective covering 11. Further details of the transfer device 2 are illustrated in the following figures.

[0047] FIG. 3 shows the transfer device 2 with the storage bottle 1 and the disposable syringe 3 in a perspective enlarged view. In this enlarged view, one can see the Luer-Lock thread 4 onto which the disposable syringe 3 has been screwed and which thus forms a liquid-tight connection with the transfer device 2. The storage bottle 1 is supported by two tube wall sections 15, 16 which are provided with a hook 17, 18 at the end. The hooks 17, 18 here grip around the neck 19 of the storage bottle 1. To release the transfer device 2, the tube wall sections 15, 16 each have a pressing surface 20, 21, where during the compression of the pressing surfaces 20, 21, the tube wall sections 15, 16 are moved radially to the outside and thereby the hooks 17, 18 release the neck 19 of the bottle.

[0048] When the transfer device 2 is placed onto the storage bottle 1, the front face 22 of the cylindrical elevation 23 abuts against a rubber seal 24B of the storage bottle 1. When the transfer device 2 is pushed further onto the storage bottle 1, the two transfer needles 8, 9 puncture the rubber seal 24 while the protective covering 11 is simultaneously compressed. The protective covering 11 is here guided via a rubber seal 24 within the cylindrical housing 25 of the transfer device 1. The rubber seal 24 and the protective covering 11 are here integrally formed, wherein at least the protective covering 11 is designed to be elastic. The end of the protective covering 11 opposed to the rubber seal 24 has a bore 26 which is placed onto a pin 27 of the intermediate part 28. The pin 27 furthermore serves to receive the two transfer needles 8, 9, the first transfer needle 8 being directly connected with the interior 30 of the disposable syringe 3 via a bore 29. The bore 29 here extends starting from the pin 27 of the transfer needle 8 via a second pin 31 to the Luer-Lock thread 4 and thus into the interior 30.

[0049] The second transfer needle 9 serves the air supply for the storage bottle 1 and is also received in the pin 27, wherein a bore 32 leads to a filter unit 10. The filter unit 10 can be seen in FIG. 7 more in detail.

[0050] FIG. 4 shows the transfer device 2, as it is already known from the previous FIGS. 1 to 3, in a side view. The lower end of the transfer device 2 has a Luer-Lock thread 4 onto which the disposable syringe (not shown) may be screwed. The Luer-Lock thread 4 is directly integrally connected with a lid 35 which is connected with the cylindrical housing 25 via two locking hooks 36 distributed across the circumference. As an alternative, it is possible to effect welding, in particular laser welding, between the lid 35 and the housing 25. The opposite end of the housing 25 has the tube wall sections 15, 16 which may grip around the neck of the storage bottle with one hook 17, 18 each not visible in this view. In the representation according to FIG. 4, a protecting cap 37 is placed on the tube wall sections 15, 16 which additionally protects the transfer device 2 from impurities and is removed when the transfer device 2 is employed. To release the transfer device 2 from the storage bottle 1, the tube wall sections 15, 16 are provided with a pressing surface 20, 21 which protrude from the cylindrical housing 25 and are connected with the housing 25 by connection via a web 38 so as to be elastically movable. If trough-shaped indentations 39 are present on the surface of the cylindrical housing 25, these are only used for improving the haptic of the housing 25.

[0051] FIG. 5 shows, in a perspective sectional view, the transfer device 2 according to FIG. 4. The protecting cap 37 is placed on the transfer device 2 and is tightly seated on the cylindrical tube wall sections 15, 16 and may be simply drawn off. For placement onto the storage bottle, the tube wall sections 15, 16 are equipped with the hooks 17, 18 which may grip around the neck of the storage bottle. The movability of the locking elements is here ensured by the pressing surfaces 20, 21 with respect to the cylindrical housing 25 so that, while the two pressing surfaces 20, 21 are compressed, the hooks 17, 18 are moved radially to the outside so that the storage bottle 1 or the neck of the bottle, respectively, are released. The two transfer needles 8, 9 are, when the transfer device 2 is not yet placed on a storage bottle 1, completely surrounded by the protective covering 11, wherein the tips of the transfer needles 8, 9 are received in a recess of the cylindrical rubber seal 24 which simultaneously serves as guidance in the cylindrical housing 25. The cylindrical rubber seal 24 and the protective covering 11 are integrally formed so that, when the protective covering 11 is compressed, the two transfer needles 8, 9 may project from the front face 22, the front face 22 being provided directly for abutment against the seal of the storage bottle 1. The transfer needle 8 is here connected with the bore of the Luer-Lock thread via a bore 29 so that sucked-in liquid will directly get into the disposable syringe. The second transfer needle 9 is in contrast connected with the filter unit 10 via a bore 32 which permits air to enter.

[0052] FIG. 6 shows the individual parts of the transfer device 2 in a perspective exploded view. As was already described in FIGS. 1 to 5, the transfer device 2 consists of a protecting cap 37, a cylindrical housing 25 with tubular wall sections 15, 16 and hooks 17, 18, wherein a release 20, 21 is possible by means of the pressing surfaces 20, 21. Within the cylindrical walls of the housing 25, the protective covering 11 with a rubber sealing 24 is movably held and pulled over the two transfer needles 8, 9 so that any contact is excluded. The two transfer needles 8, 9 can only get out of the protective covering 11 if it is pushed together like an accordion. The pushing together is only effected if the front face 22 abuts against the seal of the storage bottle 1 during placement. An intermediate part 28 serves to receive the filter unit 10, wherein the intermediate part 28 externally comprises a pin 27 which is provided for placing the protective covering 11 and simultaneously receives the two transfer needles 8, 9. A second pin 31 is located within the pot-like intermediate part 28 and permits a centrical accommodation of the individual parts of the filter unit 10. The intermediate part 28 with the filter unit 10 is furthermore closed by a lid 35 which is connected with the intermediate part 28 by means of two locking hooks 36. As an alternative, laser welding is possible. The lid 35 comprises a Luer-Lock thread 4 so that commercially available syringes may be screwed onto this Luer-Lock thread 4.

[0053] FIG. 7 shows a housing insert or inset 40 in a perspective sectional view. The housing insert or inset 40 consists of an intermediate part 28 with a filter unit 10 and a bottom 35 to which a Luer-Lock thread 4 is integrally moulded. A pin 27 protruding to the outside is provided for receiving the two transfer needles (not shown), wherein these are received in a bore 41 and 42, respectively. The transfer needles may be, for example, glued into the bore 41, 42. The bore 41 is furthermore followed by a bore 29 having a smaller diameter which directly ends in a fluid channel 43. The fluid channel 43 extends through the external connecting piece of the housing insert or inset 40 so that it ends in a connected disposable syringe with the Luer-Lock thread. Via the bore 29, 41 and the fluid channel 43, there is thus a direct connection from the disposable syringe via the transfer needle to the liquid after the storage bottle has been placed. The second transfer needle is received in the bore 42 which also passes over into a tapering bore 32. The bore 32 initially extends axially, but subsequently passes over into a radial bore 44. The radial bore 44 is guided to the filter unit 10.

[0054] The second pin 31, which receives the fluid channel 43, is provided for centring the filter unit 10. The annular space formed by the pin 31 and the outer wall serves to accommodate a valve disk 45 which is supported by a filter frame 47. The filter frame 47 has a recess 48 in which a hydrophobic filter disk 49 comes to lie and includes several openings 52. The valve disk 45 is arranged opposite to an opening 50 of the radial bore 44. To obtain a pre-tension, either the valve disk 45 is provided with a radial bulge 51, or as an alternative, the filter frame 47 may be provided with a comparable bulge. By virtue of the bulge 51, a pre-tension is created onto the valve disk 45 which leads to the air duct being closed in the rest position. This is because the bulge forces the valve disk 45 to flex when in its quiescent state, and the flexure induces within the valve disk a pre-tension, or reactive force, which urges the valve disk against the opposing surface of the filter frame 47 to form a sealing interface along the extent of the bulge where the bulge and the filter frame are in contact.

[0055] The flow conditions in normal operation are as follows. Via the Luer-Lock thread 4, the fluid channel 43, the bore 29 and 41 and the transfer needle, there is a direct connection from the disposable syringe to the interior of the storage bottle. Thus, by drawing up the disposable syringe, the medicine may be sucked from the storage bottle. If there are optionally air bubbles in the disposable syringe, these may be put back into the storage bottle by turning the complete transfer device and exerting a pressure onto the piston of the disposable syringe.

[0056] To prevent a vacuum from forming in the storage bottle, the storage bottle is connected with the filter unit 10 via the second transfer needle which is seated in the bore 42, via the bore 32, the radial bore 44 and the opening 50. By the valve disk 45 being pre-tensioned, no leakage of liquid from the storage bottle to the filter unit 10 through the provided valve disk 45 is possible. In contrast, for avoiding a vacuum in the storage bottle, air may enter the filter unit 10 via an opening. Through the hydrophobic filter disk 49 and the filter frame 47 with its openings 52 and the valve disk 45, the air gets into the opening 50 and thereby into the storage bottle via the radial bore 44 and the bore 32 and the second transfer needle. This is the normal air supply which, due to the pre-tension of the valve disk 45, only opens when there is a vacuum in the storage bottle. If via the disposable syringe, liquid, and optionally also air bubbles are supplied into the storage bottle and thus an overpressure could be formed in the storage bottle, this overpressure cannot get to the filter unit 10 via the second transfer needle, the bore 32 and the radial bore 44 because the valve disk 45 closes the opening 50. In this manner, it is ensured that no droplets of the medicine can get outside. It is moreover ensured that the hydrophobic filter 49 is not getting clogged by droplets thereby preventing air from entering through the filter unit 10. The admission of air is always required when the liquid is sucked off from the storage bottle.

[0057] FIG. 8 shows again the individual parts of the housing insert or inset 40 in a perspective exploded view. The housing insert or inset 40 consists of an intermediate part 28 with a pin 27 protruding to the outside for receiving the two transfer needles and an internal pin 31 which causes the centring of the further materials required for the filter unit 10. The intermediate part 28 has a pot-like design and thus permits to receive the further elements of the filter unit 10, wherein several gradations are present within the intermediate part 28. The opening 50 here first ends in a ring channel 2 where the valve disk 45, for example of silicone rubber, is located which has an annular bulge 51 at the edge. The valve disk 45 is followed by a filter frame 47 which is equipped with openings 52 so that air may flow into the transfer device over a large opening cross-section. Underneath the filter frame 47, a hydrophobic filter disk 49 is received in a recess, followed by a foam filter 54 which is enriched with activated carbon. The intermediate part 28 is closed by a lid 35 which permits a locking with the intermediate part 28 via two locking hooks 36. As an alternative, it is possible, to weld the lid 35 and the intermediate part 28 to each other, in particular by laser welding. The annual cavity of the intermediate part 28 is thus completely filled by the elements of the filter unit 10, and the intermediate part 28 is, after it has been assembled and sealed with the lid 35, slid into the open cylindrical end of the housing 25 of the transfer device 2. In this case, too, the intermediate part 28 may be connected with the housing 25 by means of laser welding so that a solid modular unit is available.

[0058] FIG. 9 shows the transfer device 2 with the disposable syringe 3 known from FIG. 1 in a perspective view after the disposable syringe has been filled. The transfer device 2 here permits the connection to an infusion bag 60. The infusion bag 60 has an outgoing port 61 and an incoming port 62 which is compatible with the transfer device 2. Thus, the prefilled disposable syringe with the transfer device 2 may be placed onto the port 62, and by means of the piston, the medicine may be put into the infusion bag. To this end, the two injection needles are pushed into a seal 63 of the infusion bag by pushing back the protective covering so that they obtain a connection to the interior of the infusion bag 60. Instead of the compatible port, the infusion bag 60 could also be provided with a Luer-Lock thread to be able to directly connect the disposable syringe.

[0059] FIG. 10 shows the same arrangement as FIG. 9 in a perspective view after the disposable syringe 3 with the transfer device 2 has been connected to the infusion bag 60, and the medicine has been injected into the infusion bag 60 by means of the piston 7.

LIST OF REFERENCE NUMERALS

[0060] 1 storage bottle

[0061] 2 transfer device

[0062] 3 disposable syringe

[0063] 4 Luer-Lock thread

[0064] 6 pin

[0065] 7 piston

[0066] 8 transfer needle

[0067] 9 transfer needle

[0068] 10 filter unit

[0069] 11 protective covering

[0070] 15 tube wall sections

[0071] 16 tube wall sections

[0072] 17 hook

[0073] 18 hook

[0074] 19 neck of the bottle

[0075] 20 pressing surface

[0076] 21 pressing surface

[0077] 22 front face

[0078] 23 elevation

[0079] 24 rubber seal

[0080] 25 housing

[0081] 26 bore

[0082] 27 pin

[0083] 28 intermediate part

[0084] 29 bore

[0085] 30 interior

[0086] 31 pin

[0087] 32 bore

[0088] 35 lid

[0089] 36 locking hook

[0090] 37 protecting cap

[0091] 38 web

[0092] 39 indentations

[0093] 40 housing insert or inset

[0094] 41 bore

[0095] 42 bore

[0096] 43 fluid channel

[0097] 44 radial bore

[0098] 45 valve disk

[0099] 47 filter frame

[0100] 48 recess

[0101] 49 filter disk

[0102] 50 opening

[0103] 51 bulge

[0104] 52 opening

[0105] 53 recess

[0106] 54 foam filter

[0107] 60 infusion bag

[0108] 61 port

[0109] 62 port

[0110] 63 seal

[0111] Attention is directed to all papers and documents which are filed concurrently with or previous to this specification in connection with this application and which are open to public inspection with this specification, and the contents of all such papers and documents are incorporated herein by reference.

[0112] All of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and/or all of the steps of any method or process so disclosed, may be combined in any combination, except combinations where at least some of such features and/or steps are mutually exclusive.

[0113] Each feature disclosed in this specification (including any accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise. Thus, unless expressly stated otherwise, each feature disclosed is one example only of a generic series of equivalent or similar features.

[0114] The invention is not restricted to the details of the foregoing embodiment(s). The invention extends to any novel one, or any novel combination, of the features disclosed in this specification (including any accompanying claims, abstract and drawings), or to any novel one, or any novel combination, of the steps of any method or process so disclosed.