DIETETIC PREPARATION AND DRUG FOR GLUCOSE SUPPLY AND DEMENTIA PREVENTION

Abstract

A dietetic preparation for preventing or alleviating a glucose deficiency in the brain of humans or mammals, wherein the preparation contains glucose and at least one glucose-free sweetener, wherein the mixture of glucose and glucose-free sweetener has a sweetening power of 1.5 to 3.0, in particular 2.0.

Claims

1-23. (canceled)

24. A dietetic preparation for preventing or alleviating a glucose deficiency in the brain of humans or mammals, characterized in that the preparation contains glucose and at least one glucose-free sweetener, wherein the mixture of glucose and glucose-free sweetener has a sweetening power of 1.5 to 3.0, in particular 2.0.

25. The dietetic preparation according to claim 24, characterized in that the calorific value of the mixture of glucose and glucose-free sweetener corresponds to 45% to 55% of the calorific value of an amount of sucrose with the same sweetness.

26. The dietetic preparation according to claim 24, characterized in that the preparation contains aspartame, alitame, acesulfame, a stevioside, saccharin, cyclamate, thaumatin, advantam, a suitable derivative of one of these substances, or any mixture of two or more of these substances or suitable derivatives as glucose-free sweetener.

27. The dietetic preparation according to claim 24, characterized in that the preparation contains glycine.

28. The dietetic preparation according to claim 24, characterized in that the preparation contains glucose in the form of glucose syrup.

29. The dietetic preparation according to claim 24, characterized in that the preparation contains glucose in solid crystalline or granular form.

30. The preparation according to claim 24, characterized in that the preparation comprises a transport mediator, wherein the transport mediator is an agent which improves the transport of glucose into the brain and wherein the transport mediator is in particular selected from the group of biguanides, in particular metformin, buformin or phenformin or a derivative of these substances, the group of estrogen-like natural substances, in particular resveratrol, genistein and curcumin or a derivative of these substances, the group of phytopreparations, in particular phytopreparations from the plant species Argemone mexicana, Berberis vulgaris, Coptis chinensis, Eschscholzia californica, Galega officinalis, Hydrastis Canadensis, Panax ginseng, Phellodendron amurense, Tinospora cordifolia or Xanthorhiza simplicissima, or the group of omega-3 fatty acids.

31. The preparation according to claim 30, characterized in that the transport mediator is an agent that activates the glucose transporter GLUT1, preferably an AMPK-activating agent.

32. The preparation according to claim 30, characterized in that the transport mediator is an agent from the group of biguanides.

33. The preparation according to claim 32, characterized in that the transport mediator is metformin, buformin or phenformin or a derivative of these substances.

34. The dietetic preparation according to claim 30, characterized in that the transport mediator is an estrogen-like natural substance.

35. The dietetic preparation according to claim 34, characterized in that the transport mediator is resveratrol, genistein and curcumin or a derivative of these substances.

36. The dietetic preparation according to claim 31, characterized in that the transport mediator is an AMPK-activating phytopreparation.

37. The dietetic preparation according to claim 36, characterized in that the phytopreparation is made of Panax ginseng.

38. The dietetic preparation according to claim 36, characterized in that the phytopreparation is prepared from the plant species Argemone mexicana, Berberis vulgaris, Coptis chinensis, Eschscholzia californica, Galega officinalis, Hydrastis Canadensis, Panax ginseng, Phellodendron amurense, Tinospora cordifolia or Xanthorhiza simplicissima.

39. The dietetic preparation according to claim 30, characterized in that the transport mediator is an omega-3 fatty acid.

40. The dietetic preparation according to claim 30, characterized in that between 0.5% by weight and 10% by weight of the transport mediator are contained in relation the total weight of the preparation.

41. The dietetic preparation according to claim 24, characterized in that the preparation contains a vitamin, preferably vitamin B9 and/or vitamin B12.

42. The dietetic preparation according to claim 24, characterized in that the preparation contains methionine, arginine and/or S-adenosylmethionine.

43. The dietetic preparation according to claim 24, characterized in that the preparation contains flavourings or other flavouring ingredients.

44. Treating or preventing dementia in humans and mammals, while avoiding an increased carbohydrate level in the peripheral bloodstream of the body by using a preparation according to claim 24.

45. Sweetening a nutritional product by using a preparation according to claim 24.

Description

DETAILED DESCRIPTION

Example 1: Sweetened Goat's-Rue Tea

[0054] 700 mg of a cyclamate-saccharin mixture 10:1 is carefully mixed first with 50 g glucose and then with 60 g dried goat's-rue tea. From this a total of 2.5 litres of tea can be made. The sweetened solid tea-sugar mixture is divided into 10 portions and filled into tea bags. Each tea bag is infused with 250 ml of hot water and left to brew for 7 minutes.

[0055] According to the same method, also other sweetened tea blends can be made.

Example 2: Sweetened Matcha Tea Powder and Tea

[0056] 250 mg aspartame is carefully ground with 4 g matcha powder and 4 g glucose for 10 minutes. The trituration is carefully mixed with another 11 g of matcha powder and 36 g glucose for 10 minutes.

[0057] The mixture is infused with 1 to 1.5 litres of hot water according to taste, carefully stirred and optionally filtered. The solid mixture is packaged in 10 tea bags, from each of which 150 to 200 ml of tea are made.

[0058] Flavours, dried limes, orange or lemon peel, dried strawberry or raspberry pieces, ginger powder and the like can be added to improve or vary the taste.

Example 3: Melissa Syrup with Sweetened Glucose

[0059] 7.5 g stevioside, 900 g glucose and 100 g melissa leaves are suspended in 3 litres of water. To refine the taste, sliced lemons and/or orange slices can be added. The mixture is boiled for 3 minutes. Before cooling, 80 citric acid is stirred into the warm mixture. The covered receptacle is left to stand for 36 hours at 4 to 8 C., filtered through a filter cloth and bottled. The syrup is diluted with 5 to 10 parts of water before consumption. According to the same principle, also other syrups, such as peppermint or elderflower syrup, can be made.

Example 4: Sweetened Glucose in a Vitamin Drink

[0060] 360 mg aspartame and 60 g glucose are carefully mixed with 2 g arginine, 1.5 g methionine, 1 g glycine, 5 mg vitamin B6, 300 micrograms vitamin B9 (folic acid) and 4 micrograms vitamin B12 and packaged as 20 individual units. 1 sachet corresponds to the sweetening power of 2 teaspoons of sugar. The mixture can be used to sweeten tea, coffee and lemonades.

[0061] A mixture of 360 mg aspartame and 60 g glucose, 2 g arginine, 1.5 g methionine, 1 g glycine, 5 mg vitamin B6, 300 micrograms vitamin B9 (folic acid) and 4 micrograms vitamin B12 is dissolved in one litre of tea, water or juice. The amount produced is consumed as needed, preferably in portions throughout the day.

Example 5: Sweetened Glucose in a Caffeine-Containing Drink

[0062] To 500 ml saturated soda water 0.5 g sodium carbonate, 420 mg of a cyclamate-saccharin mixture 10:1, 30 g glucose, 150 mg caffeine, 10 mg vitamin B6 and 10 micrograms vitamin B12, as well as flavouring substances and caramel color are added. The solution must be kept closed until use. The amount produced is consumed as needed, preferably in portions throughout the day.

Example 6: Sweetened Glucose in a Cola Drink

[0063] In 1 litre of soda water 325 mg aspartame, 54 g glucose, 0.5 g sodium carbonate, 100 mg caffeine, 0.5 ml phosphoric acid E338, 1 g caramel color E150d and 0.05 g cola tincture are dissolved. The cola drink obtained must be kept closed.

Example 7: Sweetened Glucose with Metformin

[0064] 7 g fine crystalline aspartame is carefully ground with 70 g fine crystalline glucose and 20 g metformin hydrochloride for 10 minutes. Then the trituration is carefully mixed with 930 g glucose for 10 minutes. The sweetening power of the mixture corresponds to that of about 2 kg or 500 teaspoons of sucrose. The mixture is either filled into sachets, pressed into cubes or packaged as a loose mixture.

Example 8: Sweetened Glucose in a Drink Containing Metformin

[0065] 360 mg aspartame and 60 g glucose are dissolved in 1 litre of water (tea). 2 g metformin, 1 g glycine, 1 g adenosylmethionine, 5 mg vitamin B6, 300 micrograms vitamin B9 (folic acid) and 4 micrograms vitamin B12 are added to this solution. The amount produced is consumed as needed, preferably in portions throughout the day.

Example 9: Sweetened Longjing Tea

[0066] 8 g Jing tea mixture is carefully ground with 125 mg aspartame and 20 g glucose. The dry mixture is divided into 4 portions and filled into tea bags, from each of which 125 ml of sweetened tea can be made by infusing with hot water.

[0067] The mixture is infused with 0.5 litres of hot water, carefully stirred and filtered through a tea filter.

[0068] According to the recipe of this example further teas of TCM can be prepared.

Example 10: Sweetened Ginseng Tea

[0069] 30 g ginseng root granules is carefully ground with 1 g of a cyclamate-saccharine mixture 10:1, and 75 g glucose. The dry mixture is divided into 10 portions and filled into tea bags, from each of which 125 ml of sweetened tea can be made by infusing with hot water.

[0070] The mixture is infused with 1.25 litres of hot water, carefully stirred, left to brew and filtered through a tea filter.

Example 11: Sweetened Glucose with Curcumin Omega-3 Fish Oil

[0071] 1 g curcumin (curcuma extract), 10 mg piperine and 0.5 g soy lecithin are carefully mixed with 2 g omega-3 fish oil. 90 mg aspartame and 15 g glucose are dissolved in 250 ml water. The oily and aqueous components are shaken to form an emulsion, wherein the aqueous phase is added in portions. The product must be kept closed. The amount produced is consumed as needed, preferably in portions throughout the day.

Example 12: Sweetened Glucose with Genistein in Omega-3 Fish Oil

[0072] 300 mg soya extract with a minimum content of 30 mg isoflavones and 0.1 g soya lecithin are mixed into 2 g omega-3 fish oil. 1.5 g aspartame, 2.5 g glycine and 15 g glucose are dissolved in 250 ml water. The oily and aqueous components are shaken to form an emulsion, wherein the aqueous phase is added in portions. The product must be kept closed. The amount produced is consumed as needed, preferably in portions throughout the day.

Example 13: Sweetened Glucose with Resveratrol in Omega-3 Fish Oil

[0073] 10 mg pure resveratrol and 0.5 g soy lecithin are mixed into 2 g omega-3 fish oil. 210 mg of a cyclamate-saccharin mixture 10:1 and 15 g glucose are dissolved in 250 ml water and 1 g glycine, 1 g adenosylmethionine, 5 mg vitamin B6, 300 micrograms vitamin B9 (folic acid) and 4 micrograms vitamin B12 are added. The oily and aqueous components are shaken to form an emulsion, wherein the aqueous phase is added in portions. The product must be kept closed. The amount produced is consumed as needed, preferably in portions throughout the day.

Example 14: Sweetened Glucose Through Blending

[0074] 7 g fine crystalline aspartame is carefully ground with 70 g fine crystalline glucose for 10 minutes. Then the trituration is carefully mixed with 930 g glucose for 10 minutes. The mixture is ready for use and can be filled into 200 sachets as single portions.

Example 15: Sweetened Glucose Through Co-Crystallization

[0075] While stirring, 950 g glucose is added in portions to a solution of 50 g cyclamate in 500 ml distilled water. The semi-solid suspension is stirred for 30 minutes and then the water is distilled off in a vacuum at a temperature of less than 40 C. The product obtained is dried in a vacuum at 40 C. for 12 hours.

Example 16: Sweetened Glucose Through Co-Crystallization

[0076] 5 g saccharin and 995 g glucose are almost completely dissolved at 30 C. in 1.5 litres of water. The solution is evaporated in a vacuum at 40 C. The solid product obtained is dried in a vacuum at 40 C. for 16 hours, then ground and sieved.

Example 17: Sweetened Glucose Refined with Glycine

[0077] 6 g crystalline aspartame, 10 g crystalline glycine and 60 g glucose are carefully ground for 10 minutes. Then the trituration is carefully mixed with 930 g glucose for 10 minutes. The mixture is ready to use.