Spatiotemporal magnetic field monitoring with hall effect sensors during the MRI scan
10641858 · 2020-05-05
Assignee
Inventors
- Ergin Atalar (Ankara, TR)
- Soheil Taraghinia (Ankara, TR)
- Niyazi Koray Ertan (Ankara, TR)
- Bilal Taşdelen (Osmangazi/Bursa, TR)
Cpc classification
G01R33/3852
PHYSICS
A61B5/055
HUMAN NECESSITIES
G01R33/4625
PHYSICS
A61B5/05
HUMAN NECESSITIES
G01R33/0035
PHYSICS
G01R33/072
PHYSICS
International classification
G01R33/565
PHYSICS
G01R33/00
PHYSICS
A61B5/055
HUMAN NECESSITIES
Abstract
An MRI system includes a gantry having a longitudinal axis (herein z-axis) and a magnet disposed about the gantry for generating a static magnetic field along the longitudinal axis. Additionally, the system comprises a first gradient magnet for generating a gradient magnetic field along the longitudinal axis; a second gradient magnet for generating a gradient magnetic field along a first transverse direction (herein x-axis) orthogonal the longitudinal axis; and a third gradient magnet for generating a gradient magnetic field along a second transverse direction (herein y-axis) orthogonal to the longitudinal axis and the first transverse direction. Magnetic sensors are positioned relative to the gantry to measure gradients of transverse components of magnetic field along one or more of the x, y and z axes. A controller receives measurement signals from the sensors and operates on those signals to determine gradients of the gradient magnetic field along the longitudinal axis.
Claims
1. A magnetic resonance imaging (MRI) system, comprising: a gantry for receiving a subject, said gantry having a longitudinal axis (herein z-axis); a magnet disposed about said gantry for generating a static magnetic field along said longitudinal axis of the gantry; a first gradient magnet for generating a gradient magnetic field along said longitudinal axis; a second gradient magnet for generating a gradient magnetic field along a first transverse direction (herein x-axis) orthogonal said longitudinal axis; a third gradient magnet for generating a gradient magnetic field along a second transverse direction (herein y-axis) orthogonal to said longitudinal axis and said first transverse direction; a plurality of magnetic sensors positioned relative to the gantry for measuring gradients of transverse components of magnetic field along one or more of the x, y and z axes, said magnetic sensors generating signals indicative of said measured transverse magnetic field gradients; and a controller for receiving said signals and operating on said signals to determine gradients of the gradient magnetic field along said longitudinal axis.
2. The MRI system of claim 1, wherein said magnetic sensors comprise Hall effect sensors.
3. The MRI system of claim 1, wherein said controller determines said longitudinal magnetic field gradients for said at least one location by using the following relations:
4. The MRI system of claim 1, wherein said controller receives calibration signals from said plurality of sensors in absence of applied magnetic fields and employs said calibration signals for calibrating said magnetic sensors.
5. The MRI system of claim 1, further comprising a mechanical holder to which said plurality of magnetic sensors can be mounted, said mechanical holder being positioned relative to said gantry and being configured to provide coordinates of each of said plurality of magnetic sensors along x, y, and z-axes.
6. The MRI system of claim 1, further comprising at least one alignment mechanism for aligning at least one of said plurality of magnetic sensors along any of said x and y-axes for measuring magnetic fields along said axes.
7. The MRI system of claim 6, wherein said at least one alignment mechanism comprises a piezoelectric actuator coupled to said at least one of said plurality of magnetic sensors.
8. The MRI system of claim 7, wherein said at least one alignment mechanism operates under control of said controller.
9. The MRI system of claim 8, wherein said controller instructs said alignment mechanism to adjust an orientation of said at least one sensor based on an output voltage signal generated by said least one sensor.
10. The MRI system of claim 9, wherein said alignment mechanism is configured to rotate said sensor in response to a control signal from said controller so as to align said at least one sensor along on of said x and y-axes.
11. A method for measuring a gradient magnetic field in a magnetic resonance system, comprising: positioning a plurality of magnetic sensors relative to a longitudinal axis (herein z-axis) of a gantry; using the plurality of magnetic sensors to collect measurements indicative of: a measurement of a gradient magnetic field along a first transverse direction (herein x-axis) orthogonal to the longitudinal axis, and a measurement of a gradient magnetic field along a second transverse direction (herein y-axis) orthogonal to the longitudinal axis and the first transverse direction; determining a measurement of a gradient magnetic field along the z-axis based on the measurement of the gradient magnetic field along the x-axis and the measurement of a gradient magnetic field along the y-axis.
12. The method of claim 11, wherein the magnetic sensors comprise Hall effect sensors.
13. The method of claim 11, wherein the plurality of magnetic sensors is located within a mechanical holder and positioning the plurality of magnetic sensors relative to the z-axis comprises: aligning the mechanical holder with the z-axis.
14. The method of claim 13, wherein the mechanical holder is aligned using a piezoelectric actuator.
15. The method of claim 14, wherein the piezoelectric actuator aligns the mechanical holder based on signals generated by the plurality of magnetic sensors.
16. A magnetic resonance imaging (MRI) system, comprising: a plurality of magnetic sensors positioned relative to a longitudinal axis (herein z-axis) of a gantry, wherein the plurality of magnetic sensors are configured to collect measurements during an MRI scan comprising: a measurement of a gradient magnetic field along a first transverse direction (herein x-axis) orthogonal to the longitudinal axis, and a measurement of a gradient magnetic field along a second transverse direction (herein y-axis) orthogonal to the longitudinal axis and the first transverse direction; and one or more computers configured to determine a measurement of a gradient magnetic field along the z-axis based on the measurement of the gradient magnetic field along the x-axis and the measurement of the gradient magnetic field along the y-axis.
17. The MRI system of claim 16, wherein the y-axis is orthogonal the x-axis.
18. The MRI system of claim 16, wherein the one or more computers are further configured to: estimate a k-space trajectory of the MRI scan based on the measurement of the gradient magnetic field along the x-axis and the measurement of the gradient magnetic field along the y-axis; and use the k-space trajectory to reconstruct one or more images based on k-space data acquired during the MRI scan.
19. The MRI system of claim 17, wherein the one or more computers are further configured to: estimate patient motion data based on the measurement of the gradient magnetic field along the x-axis and the measurement of the gradient magnetic field along the y-axis; and using the patient motion data to perform motion correction on the one or more images.
20. The MRI system of claim 16, wherein the plurality of magnetic sensors are Hall effect sensors.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1) The foregoing and other aspects of the present invention are best understood from the following detailed description when read in connection with the accompanying drawings. For the purpose of illustrating the invention, there are shown in the drawings embodiments that are presently preferred, it being understood, however, that the invention is not limited to the specific instrumentalities disclosed. Included in the drawings are the following Figures:
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
DETAILED DESCRIPTION
(13) The following disclosure describes the present invention according to several embodiments directed at methods, systems, and apparatuses that perform spatiotemporal magnetic field monitoring with hall effect sensors during the magnetic resonance imaging (MRI) scan. More specifically, Hall effect sensors are used to monitor the spatiotemporal field dynamics of the gradient fields in MRI. Measurement of the z component of the magnetic field (B.sub.z) requires very large dynamic range for the Hall effect sensors due to superposition of encoding fields with main magnetic field (B.sub.0). To address this requirement, the techniques described herein measure the transverse components of the magnetic field in several spatial positions to reconstruct spatiotemporal dependency of Bz. In other words, the transverse magnetic fields can be measured because a static magnetic field does not cause saturation of the sensors and additionally, the spatial map of the magnetic field may be reconstructed up to a desired order of spherical harmonics depending on the number of sensors.
(14)
(15) A magnet (not shown in
(16) A plurality of magnetic sensors 115 are positioned relative to the bore 105 to measure magnitude of the magnetic field at multiple points. From these multiple measurements, the spherical harmonic coefficients of the x- and y-oriented magnetic fields are estimated (as described in further detail below). Later, using the Maxwell equations, the spherical order coefficients of the z-oriented field are obtained. A support structure 125 is used to hold the plurality of magnetic sensors 115 in a fixed position so that, after initial calibration, the plurality of magnetic sensors 115 will stay perpendicular to z position when they are moved to other position. In some embodiments, the support structure 125 is positioned to avoid physical contact with the scanner in order to minimize movement of the support structure 125 due to vibration modulation of the scanner. An additional apparatus may be connected to holder in order to determine the exact position of the sensors.
(17) In general, the magnetic sensors 115 can perform any magnetic field measurement method that directly measures the transverse component and approximates the longitudinal component. For example, in one embodiment, the magnetic sensors are Hall effect sensors. As would be understood by one skilled in the art, the Hall effect is the production of a voltage difference across an electrical conductor when a magnetic field is applied in a direction perpendicular to that of the flow of current. This voltage difference is referred to as the Hall voltage. A Hall effect sensor is a transducer that measures the Hall voltage across the two faces of the transducer when it is placed in a magnetic field (in this case, within the bore 105).
(18) The plurality of magnetic sensors 115 shown in
(19) In order to calibrate the system, some parameters related to sensors may be measured before they are embedded in the system to increase the accuracy of the system. First, due to its potential variance during operations, output voltage of the sensors to zero magnetic field may be calibrated. Second, sensitivity of the sensors may be measured outside of the system with a reliable magnetic field source and voltage measurement device such as oscilloscope to determine the exact sensitivity of the voltage. The output voltage of the sensors can also vary as a function of frequency and frequency response can be calculated. The frequency response can be used to deconvolve the output signals to further increase the accuracy of the system.
(20) Where Hall effect sensors are employed, the locations of the plurality of magnetic sensors 115 should be known in order to solve spherical harmonics equations. There are various ways of measuring the sensor location. In some embodiments, small phantoms are imaged using the MRI to determine the locations of the phantoms in the MR scanner coordinate system. Sensor locations can then be measured at the production stage of the mechanical cover or they can be measured with any conventional measurement technique generally known in the art. In other embodiments, a mechanical holder for the sensors is positioned relative to said bore and configured to provide coordinates of each of the sensors along x, y, and z-axes. This mechanical holder may be mounted, for example, on a conventional RF receive coil's mechanical holder. In still other embodiments, one or more electrical devices are used to measure the location of the sensors such as visible and non-visible optics, gyroscopes etc.
(21) Mechanical vibration of the MRI scanner can also vibrate the plurality of magnetic sensors during scanning. In turn, the sensor vibration can cause modulation of the sensors with the z direction and result in a changing magnetic field due to changing angle with the main magnetic field. Sensors should not physically contact with the MRI scanner because vibration of the scanner can modulate the angle of the sensors in both longitudinal and transverse angles. Modulation in the z direction has severe effects on the main magnetic field B.sub.0. This effect may be reduced by placing the sensors in a mechanical cover with no direct physical contact with the MRI scanner system (as shown in
(22) Continuing with reference to
(23) As an example of the operations performed by the controller 120 in embodiments where the plurality of magnetic sensors 115 are Hall effect sensors, consider the following. The Hall effect sensors are used to measure directly B.sub.z inside the bore 105; however field deviations are on the order of parts-per-million of the B.sub.0 need to be monitored because such deviations can cause artifacts in the images. Such a high dynamic range results in either very low sensitivity or saturation of the MRI sensor. Ideally, when Hall elements are aligned to measure concomitant fields, there will be no interference with the main magnetic fields which will not cause saturation and high sensitivity can be maintained. Additionally, if the direction of the current in Hall element is aligned with the z-direction inside the MRI scanner, the wavelength at the gradient frequencies are very long (104 m), Maxwell equations can be written as follows:
(24)
(25) The last partial derivative of the Bz can be determined from the zero divergence condition as in Equation 2. Therefore, knowledge of transverse fields is adequate to determine the partial derivatives of the B.sub.z (i.e., B.sub.z). However, the spatial direct current (DC) component is not included in this formulation. This DC component can be calculated by assuming that all magnetic fields decay at a distant location as an additional equation. Alternatively, the spatially constant term (i.e., the DC component) may be determined using an additional NMR probe for the direct measurement of the frequency. Because the DC term is not used to calculate B.sub.z, measurement at three points is adequate to measure first order spherical harmonics of B.sub.x and B.sub.y. Note that, at each point there are two sensors oriented for x- and y-directions respectively; therefore, their physical locations are very close but not exactly same. The sensors can even be physically separated by some distance; as long as there are enough sensors for each direction to allow reconstruction of the B.sub.x and B.sub.y fields, the B.sub.z field can be reconstructed. Afterwards, using Equations 1 and 2, B.sub.z can be calculated up to same order spherical harmonics with B.sub.x and B.sub.y. When spherical harmonic terms with unknown coefficients are inserted into Equations 1 and 2, unknown coefficients can be solved by trivial algebraic and analytical expressions or matrix inversion techniques generally known in the art.
(26) Alignment of the plurality of sensors 115 with the z direction is very critical because even few degrees of coupling are enough to saturate the sensors due to the high static field. For example, in the 1 Volt measurement range, 23 mV/mT sensitivity and 3 Tesla B.sub.0 results in a 0.83 degree coupling, which is enough to completely saturate the sensor and similarly this leads to a decrease in the accuracy of the transverse measurements because measurements are multiplied with the cosine of the alignment angle (i.e., cos()).
(27) To address the alignment issues discussed above, various strategies may be employed. For example, in some embodiments, the sensors are manually aligned. In other embodiments, sensors are placed on a mechanical holder which is compatible with the MRI coordinate system. For example in one embodiment, sensors are placed to a precisely manufactured 3D printed cube which has holes on the four sides. Sensors exactly fit to the holes in the cube, which provides the 90 degree alignment of the sensors in the transverse direction. Even if sensors are not aligned in the transverse plane, it is possible to calibrate the system by applying currents to conventional MRI gradient coils. Furthermore, in these embodiments, there may be an additional hole inside the cube where a wire can be placed. When DC current is applied to a wire in the hole, the wire is aligned with z direction due to Lorentz Force induced by the main magnetic field. In this way, alignment in the longitudinal direction can be satisfied.
(28) In other embodiments, an alignment mechanism placed outside of the scanner is used actively to align the sensors by receiving a feedback signal from the output voltage of a sensor because the zero magnetic field output voltage of the sensors are already known. A framework for performing this method is shown in
(29)
(30) The results gathered via monitoring of spatiotemporal magnetic field monitoring can be employed to correct various imperfections and other deviations from ideal conditions that arise during image acquisition. For example, gradient field imperfections are known; therefore, effect of them can be corrected in the image reconstruction. Additionally, the gradient field measurements can be used as a feedback for gradient system itself to correct the gradient system imperfections. Moreover, if the sensors are in physical contact with the patient, patient motion data can be characterized from these field measurements and the effect of patient motion can be corrected in the image post-processing part or sequence itself can be adapted to such motions in real time.
(31)
(32)
(33)
(34)
(35) In order to digitize the data, an Analog to Digital Converter (ADC) with enough temporal resolution and signal-to-noise ratio (SNR) should be used. ADC frequency can be determined by the cutoff frequency of the low pass filter at the output of the sensor and this cutoff frequency should be determined according to noise level of the sensor and required SNR of the gradient field measurements. There is a trivial tradeoff between bandwidth of the sensors and SNR of the magnetic field measurements. Ideally, the ADC should be placed near the sensors as much as possible because eddy current due to E-fields can cause undesired voltage induction in the output cables of the sensors and digitizing the data directly next to sensors is beneficial to minimize the E-field effect. After digitizing the data, data can be carried to processing unit as optical, low-voltage differential signaling (LVDS) or using conventional methods depending on the required data speed, noise level and distance. Also the ADC can be used in a time multiplexed manner to better occupy the bandwidth. In other words, any parallel acquisition of the data from the sensors can be employed.
(36) In one example implementation of the techniques described herein, sensors were placed at certain locations in the bore of the MRI scanner and a calibration gradient waveform was applied in each direction. In order to neglect frequency dependent errors, sensor outputs were measured when calibration gradient waveforms were at the flat top. Furthermore, data was acquired with much higher bandwidth than the sensors have; therefore data was digitally low-pass filtered. Example calibration data and low pass filtered results are shown in
(37)
(38) The main magnet 22, the gradient coil 24, and the RF coil 26 are disposed in a predetermined direction of the gantry 20. The predetermined direction may include a coaxial cylindrical direction, or the like. The object 10 may be positioned on a table 28 insertable into a cylinder along a horizontal axis of the cylinder. The main magnet 22 may generate a static magnetic field for aligning a magnetic dipole moment of the atomic nuclei included in the object 10 in a predetermined direction. As the magnetic field generated by the main magnet is stronger and more uniform, a relatively precise and accurate MR image with respect to the object 10 may be obtained.
(39) The gradient coil 24 includes X, Y, and Z coils that generate gradient magnetic fields in mutually orthogonal X-, Y-, and Z-axis directions. The gradient coil 24 may provide positional information of each part of the object 10 by inducing resonance frequencies differently for each part of the object 10.
(40) The RF coil 26 irradiates RF signals to a patient and receives magnetic resonance signals emitted from the patient. For example, the RF coil 26 may transmit an RF signal having a frequency equal to a frequency of a processional motion toward the atomic nucleus which performs the processional motion to the patient and thereafter, stop transmission of the RF signal and receive the magnetic resonance signal emitted from the patient. For example, the RF coil 26 may generate an electromagnetic signal, having a radio frequency corresponding to the type of atomic nucleus, for example, an RF signal, and apply the generated RF signal to the object 10 so as to transition a certain atomic nucleus from a low energy state to a high energy state. When the electromagnetic signal generated by the RF coil 26 is applied to the certain atomic nucleus, the certain atomic nucleus may transition from the low energy state to the high energy state. Thereafter, when the electromagnetic wave generated by the RF coil 26 is removed, the atomic nucleus to which the electromagnetic wave has been applied may emit electromagnetic waves having a Larmor frequency while transitioning from the high energy state to the low energy state. In other words, when the application of the electromagnetic signal to the atomic nucleus is interrupted, and the atomic nucleus to which the electromagnetic wave is applied transitions from a high-energy state to a low-energy state, the electromagnetic wave having the Larmor frequency may be emitted. Here, the Larmor frequency may mean a frequency at which magnetic resonance is induced in the atomic nucleus.
(41) The RF coil 26 receives the electromagnetic signals irradiated from the atomic nuclei inside the object 10. The RF coil 26 may be implemented as one RF transceiving coil having both a function of generating the electromagnetic wave having the radio frequency corresponding to the type of the atomic nucleus and a function of receiving the electromagnetic waves irradiated from the atomic nucleus. Further, the RF coil 26 may be implemented as each of a transmission RF coil having the function of generating the electromagnetic wave having the radio frequency corresponding to the type of atomic nucleus and a reception RF coil having the function of receiving the electromagnetic wave irradiated from the atomic nucleus.
(42) Further, the RF coil 26 may be fixed to the gantry 20 and may be removable. The removable RF coil 26 may include RF coils for a portion of the object including a head RF coil, a thorax RF coil, a leg RF coil, a neck RF coil, a shoulder RF coil, a wrist RF coil, and an ankle RF coil. The RF coil 26 may communicate with an external device by a wired and/or wireless manner and may perform even dual tune communication according to a communication frequency band. The RF coil 26 may include RF coils of various channels such as 16 channels, 32 channels, 72 channels, and 144 channels.
(43) The gantry 20 may include a display 29 positioned outside the gantry 20 and a display (not illustrated in
(44) The signal transceiving unit 30 controls a gradient magnetic field formed in the gantry 20 according to a predetermined MR sequence and control transmission and reception of the RF signal and the magnetic resonance signal. The signal transceiving unit 30 includes a gradient amplifier 32, a transceiving switch 34, an RF transmitting unit 36, and an RF receiving unit 38.
(45) The gradient amplifier 32 may drive the gradient coil 24 included in the gantry 20 and supply a pulse signal for generating the gradient magnetic field to the gradient coil 24 under the control of the gradient magnetic field control unit 54.
(46) The gradient magnetic field control unit 54 may control the pulse signal supplied from the gradient amplifier 32 to the gradient coil 24. By controlling the pulse signal supplied to the gradient coil 24, the gradient magnetic fields in X-axis, Y-axis, and Z-axis directions may be synthesized. The pulse signal may be implemented by current.
(47) The RF transmitting unit 36 and the RF receiving unit 38 may drive the RF coil 26. The RF transmitting unit 36 may supply the RF pulse of the Larmor frequency to the RF coil 26 and the RF receiving unit 38 may receive the magnetic resonance signal received by the RF coil 26.
(48) The transceiving switch 34 adjusts transmission/reception directions of the RF signal and the magnetic resonance signal. For example, the transceiving switch 34 may cause the RF signal to be irradiated to the object 10 through the RF coil 26 during a transmission mode and the magnetic resonance signal from the object 10 through the RF coil 26 to be received during a reception mode. The transceiving switch 34 may be controlled by a control signal from an RF control unit 56.
(49) The monitoring unit 40 monitors or controls the gantry 20 or devices mounted on the gantry 20. The monitoring unit 40 includes a system monitoring unit 42, an object monitoring unit 44, a table control unit 46, and a display control unit 48.
(50) The system monitoring unit 42 may monitor and control a state of the static magnetic field, the state of the gradient magnetic field, the state of the RF signal, the state of the RF coil, the state of a table, the state of a device for measuring body information of the object, a power supply state, the state of a heat exchanger, the state of a compressor, and the like.
(51) The object monitoring unit 44 may monitor the state of the object 10. For example, the object monitoring unit 44 includes a camera for observing a motion or a position of the object 10, a respiration measuring unit for measuring respiration of the object 10, an ECG measurer for measuring an electrocardiogram of the object 10, or a body temperature measurer for measuring a body temperature of the object 10.
(52) The table control unit 46 may control movement of the table 28 at which the object 10 is positioned. The table control unit 46 may control the movement of the table 28 according to sequence control of the sequence control unit 52. For example, in moving imaging of the object, the table control unit 46 may continuously or intermittently move the table 28 according to the sequence control by the sequence control unit 52 to thereby photograph the object in a field of view (FOV) larger than the FOV of the gantry.
(53) The display control unit 48 may control the displays positioned outside and inside the gantry 20. For example, the display control unit 48 may control on/off of the displays positioned outside and inside the gantry 20 or a screen to be output to the display. Further, when a speaker is positioned inside or outside the gantry 20, the display control unit 48 may control the on/off of the speaker or a sound to be output through the speaker.
(54) The system control unit 50 includes a sequence control unit 52 for controlling a sequence of signals formed in the gantry 20 and a gantry control unit 58 for controlling the devices mounted on the gantry 20.
(55) The sequence control unit 52 includes the gradient magnetic field control unit 54 for controlling the gradient amplifier 32 and the RF control unit 56. The RF control unit 56 may control the RF transmitting unit 36, the RF receiving unit 38, and the transceiving switch 34. The sequence control unit 52 may control the gradient amplifier 32, the RF transmitting unit 36, the RF receiving unit 38, and the transceiving switch 34 according to a pulse sequence received from the operating unit 60. Here, the pulse sequence includes all information required for controlling the gradient amplifier 32, the RF transmitting unit 36, the RF receiving unit 38, and the transceiving switch 34 and may include, for example, information on the intensity, an application time, an application timing, and the like of the pulse signal applied to the gradient coil 24.
(56) The operating unit 60 provides instructions corresponding to the pulse sequence information to the system control unit 50 and control an operation of the entire MRI apparatus. The operating unit 60 includes an image processing unit 62 for processing the magnetic resonance signal received from the RF receiving unit 38, an output unit 64, and an input unit 66.
(57) The image processing unit 62 processes the magnetic resonance signal received from the RF receiving unit 38 to generate magnetic resonance image data for the object 10. The image processing unit 62 may perform various signal processing such as amplification, frequency conversion, phase detection, low frequency amplification, filtering, and the like on the magnetic resonance signal received by the RF receiving unit 38. The image processing unit 62 arranges digital data in k-space data (also referred to as, for example, a Fourier space or a frequency space) of a memory and performs two-dimensional or three-dimensional Fourier transformation of the data to reconfigure the data into image data. Further, the image processing unit 62 may perform synthesis processing or difference arithmetic processing of the image data as necessary. In addition, various signal processing applied to the magnetic resonance signal by the image processing unit 62 may be performed in parallel. For example, a plurality of magnetic resonance signals may be reconfigured into the image data by applying signal processing in parallel to the plurality of magnetic resonance signals received by a multi-channel RF coil.
(58) The output unit 64 may output the image data or the reconfigured image data generated by the image processing unit 62 to the user. In addition, the output unit 64 may output information required for the user to operate the MRI apparatus, such as a UI (user interface), user information, or object information. The output unit 64 may include, for example, a speaker, a printer, a CRT display, an LCD display, a PDP display, an OLED display, an FED display, an LED display, a VFD display, a DLP display, a PFD display, a 3D display, a transparent display, and the like and may include a variety of output devices within other scopes which are apparent to those skilled in the art. The user may input object information, parameter information, a scan condition, the pulse sequence, information on image synthesis and calculation of difference, and the like using the input unit 66. The input unit 66 may include a keyboard, a mouse, a trackball, a voice recognition unit, a gesture recognition unit, a touch screen, and the like and may include various input devices within the other scopes which are apparent to those skilled in the art.
(59) The functions and process steps herein may be performed automatically, wholly or partially in response to user command. An activity (including a step) performed automatically is performed in response to one or more executable instructions or device operation without user direct initiation of the activity.
(60) The system and processes of the figures are not exclusive. Other systems, processes and menus may be derived in accordance with the principles of the invention to accomplish the same objectives. Although this invention has been described with reference to particular embodiments, it is to be understood that the embodiments and variations shown and described herein are for illustration purposes only. Modifications to the current design may be implemented by those skilled in the art, without departing from the scope of the invention. As described herein, the various systems, subsystems, agents, managers and processes can be implemented using hardware components, software components, and/or combinations thereof. No claim element herein is to be construed under the provisions of 35 U.S.C. 112(f), unless the element is expressly recited using the phrase means for.