Medicament delivery device

Abstract

Examples include a medicament delivery device including a housing, a medicament delivery member assembly configured to be moved from an initial position to a penetration position and from the penetration position back to the initial position, a penetration and withdrawal mechanism, an activation mechanism, and a stop mechanism, where the penetration and withdrawal mechanism includes a driver operably connected to the medicament delivery member assembly and to the activation and stop mechanism, a drive element operably connected to the driver, a biased force element connected to the drive element, and a switching element arranged between the driver and the drive element, where operation of the stop mechanism allows the biased force element to interact with the drive element, causing movement of the switching element such that the driver is moved in an opposite direction and moves the medicament delivery member assembly back to the initial position.

Claims

1. A medicament delivery device comprising: a housing; a medicament delivery member; a rotator sleeve configured to control movement of the medicament delivery member, wherein the medicament delivery member is arranged coaxially with the rotator sleeve; a first button; a second button; a drive element; a biased force element; and a switching element, wherein operation of the first button is configured to cause the biased force element to interact with the drive element, causing movement of the switching element such that the rotator sleeve is moved in a first rotational direction to move the medicament delivery member coaxially with respect to the rotator sleeve to a penetration position from an initial position; and wherein operation of the second button is configured to cause the biased force element to further interact with the drive element, causing movement of the switching element such that the rotator sleeve is moved in a second rotational direction that is opposite the first rotational direction to move the medicament delivery member coaxially with respect to the rotator sleeve back to the initial position.

2. The medicament delivery device according to claim 1, wherein the drive element comprises a flexible, non-elastic band wound around the rotator sleeve.

3. The medicament delivery device according to claim 1, wherein pulling of the drive element is configured to cause rotation of the rotator sleeve, in turn causing a linear movement of the medicament delivery member.

4. The medicament delivery device according to claim 1, wherein the rotator sleeve comprises a spiral-shaped groove.

5. The medicament delivery device according to claim 4, wherein the spiral-shaped groove is suitable for cooperating with protrusions on the medicament delivery member.

6. The medicament delivery device according to claim 1, wherein the housing comprises a tubular post provided with a groove.

7. The medicament delivery device according to claim 6, wherein the medicament delivery member is arranged to fit into the tubular post and is provided with protrusions fitting into the groove.

8. The medicament delivery device according to claim 1, wherein the switching element is releasably attached to the rotator sleeve.

9. The medicament delivery device according to claim 1, wherein the switching element is arranged to alter a winding direction of the drive element around the rotator sleeve.

10. The medicament delivery device according to claim 1, wherein the switching element is configured to detach from the rotator sleeve when the medicament delivery member has reached the penetration position.

11. The medicament delivery device according to claim 1, wherein the switching element comprises a pin.

12. The medicament delivery device according to claim 11, wherein the switching element further comprises a band that is wound around the pin and configured for reversing a winding direction of the drive element around the rotator sleeve.

13. The medicament delivery device according to claim 1, wherein the first button is configured to lock the rotator sleeve in a non-activated position.

14. The medicament delivery device according to claim 13, wherein the first button is manually operable release the rotator sleeve.

15. The medicament delivery device according to claim 1, wherein the second button is configured to lock the rotator sleeve in the penetration position.

16. The medicament delivery device according to claim 15, wherein the second button is arranged to release the rotator sleeve.

17. The medicament delivery device according to claim 1, further comprising an electrical drive unit configured upon activation to expel a dose of medicament from a medicament container arranged in the medicament delivery device.

18. The medicament delivery device according to claim 17, wherein the electrical drive unit is configured to be activated by the first button.

19. The medicament delivery device according to claim 17, wherein the electrical drive unit is configured to be deactivated by the second button.

20. The medicament delivery device according to claim 1, further comprising a medicament delivery member holder comprising a central transversal wall to which the medicament delivery member is attached, the medicament delivery member comprising a pointed penetration end and a connection end for a conduit for medicament.

21. The medicament delivery device according to claim 1, wherein the rotator sleeve is operably connected to the medicament delivery member and to the drive element, wherein said switching element is releasably attached to said rotator sleeve, wherein said switching element is arranged to alter a winding direction of said drive element around said rotator sleeve, and wherein said switching element is detached from said rotator sleeve when the medicament delivery member has reached said penetration position.

Description

BRIEF DESCRIPTION OF DRAWINGS

(1) In the following detailed description of the invention, reference will be made to the accompanying drawings, of which

(2) FIG. 1 is a perspective view of a medicament delivery device according to the invention,

(3) FIG. 2 is a perspective view of the medicament delivery device of FIG. 1 with a housing part removed,

(4) FIG. 3 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(5) FIG. 4 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(6) FIG. 5 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(7) FIG. 6 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(8) FIG. 7 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(9) FIG. 8 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(10) FIG. 9 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(11) FIG. 10 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(12) FIG. 11 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(13) FIG. 12 is a detailed view of components comprised in the medicament delivery device of FIG. 1.

(14) FIG. 13 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(15) FIG. 14 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(16) FIG. 15 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(17) FIG. 16 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(18) FIG. 17 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(19) FIG. 18 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(20) FIG. 19 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(21) FIG. 20 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

(22) FIG. 21 is a detailed view of a functional state of the medicament delivery device of FIG. 1.

DETAILED DESCRIPTION OF THE INVENTION

(23) The exemplary embodiment shown in the drawings comprises a proximal housing part 10 and a distal housing part 12, FIG. 1. It is however to be understood that the device can comprise further housing parts depending on design and production issues. The housing parts are arranged to accommodate a number of elements and mechanisms as will be described. Preferably, the assembled housing has a generally flat, rectangular shape having a measure or thickness, viewed along a proximal-distal axis, PDA, that is much less than the dimensions in the other two directions, vertical axis VA and horizontal axis HA. The distal housing part 12 is preferably arranged with a lid 13 for access to the interior of the medicament delivery device.

(24) An activation mechanism 14 is arranged in the device for activating different functions of the device as will be described, see FIG. 2. The activation mechanism 14 comprises a push button 16, FIGS. 1 to 3, i.e. a start button, extending through a passage of the distal housing part 12. The start button 16 comprises a generally tubular body 20 provided with an end wall 22, FIG. 3, which acts as contact surface for a user as will be described. The end wall 22 of the start button 16 may be arranged with indicia that provide the user with information regarding its function, such as the word ON, indicating to a user that this is the button that activates the device. A centrally positioned shaft 24 is arranged on the end wall, extending in the proximal direction. The shaft 24 is arranged to fit into a generally tubular guide post 26 in the proximal housing part 10, FIG. 4.

(25) The body 20 of the start button 16 is further arranged with a cut-out 28, FIG. 3. One side surface 30 of the cut-out is arranged with an inclination, which inclination is intended to act on an inclined surface 32 of a start locking element 34 of the activation mechanism 14. The start locking element 34 is provided with a downwardly directed seat portion 36 that is designed to fit into a corresponding post 38, FIG. 4, arranged on the inner surface of the distal housing part 10. Further the start locking element 34 is arranged with flexible, inclined, arms 40 that are to interact with posts 42 arranged at the edge of the post 38 of the distal housing part 10. The start locking element 34 is further arranged with a protrusion 44 provided with side surfaces. The protrusion 44 is arranged to interact with a corresponding protrusion 46 on a driver that in the embodiment shown is designed as a generally tubular rotator sleeve 48, FIG. 5, comprised in a penetration and withdrawal mechanism. The protrusion 46 on the rotator sleeve 48 is attached to a generally radially outwardly extending tongue 50. The rotator sleeve 48 is journalled on a generally tubular post 52 arranged on the inner surface of the proximal housing part, FIG. 4. The rotator sleeve 48 is also arranged with two outwardly directed tongues 54, which are placed in line with each other as seen in the longitudinal direction of the rotator sleeve 48, FIG. 5a. Each tongue 54 is arranged with a generally semi-circular cut-out 56 as well as a hole or passage 58, the functions of which will be described below. The rotator sleeve 48 is further arranged with two spiral grooves 60 on its inner surface extending on opposite sides thereof.

(26) A medicament delivery member assembly is further arranged, comprising a medicament delivery member holder 62 of a generally tubular shape is arranged in the post 52, FIG. 2, of the proximal housing part 10. The medicament delivery member holder 62 has a central transversal wall 64 to which a medicament delivery member 66 is attached, having a pointed penetration end and a connection end for a conduit 67 for medicament, FIG. 2. The medicament delivery member holder 62 is arranged with outwardly extending, generally rectangular protrusions 68 on opposite sides. These rectangular protrusions 68 are arranged to fit into longitudinally extending grooves 70 in the post 52, FIG. 4, thereby allowing linear movement of the medicament delivery member holder 62, but providing a rotational lock. Radially outside the rectangular protrusions 68, generally cylindrical protrusions 72 are arranged, which cylindrical protrusions 72 are intended to fit into the spiral grooves 60 of the rotator sleeve 48.

(27) Further, a thin band-shaped element 74, a drive element, comprised in the penetration and withdrawal mechanism, FIG. 6, is connected to the rotator sleeve 48 with an end piece that is bent around a first attachment pin 76, FIG. 7, which first attachment pin 76 extends through the holes 58 of the tongues 54 of the rotator sleeve 48. As seen in FIG. 7b, the drive element 74 is then wound around the outer surface of the rotator sleeve 48 in a clockwise direction almost 360 degrees. It is then wound 180 degrees around a second attachment pin 78, also comprised in the penetration and withdrawal mechanism, which second attachment pin 78 is placed in the semi-circular cut-outs 56 of the tongues 54 of the rotator sleeve 48. The drive element 74 is then fed anti-clockwise around the rotator sleeve 48 and then outside a generally arc-shaped support wall 80, FIG. 4. An edge of the support wall 80 is arranged with a seat 82, into which seat 82 the second attachment pin 78 will be placed as described below.

(28) The drive element 74 then extends along the inner of the proximal housing part up to a post 84, FIG. 2, provided with a rounded support surface, around which the drive element 74 is wound. The free end of the drive element 74 is then attached to a force element in the form of a clock spring 86, FIGS. 2 and 6, also comprised in the penetration and withdrawal mechanism. The force element 86 is wound around a generally cylindrical spring hub 88 with an inner end attached to the spring hub 88, which in turn is journalled on a post 90 fixed in the proximal housing part 10.

(29) The proximal housing part 10 is further arranged to accommodate a medicament container 92, FIG. 2. In the preferred embodiment, the medicament container 92 comprises a generally tubular body with a first end arranged with a passage. Inside the passage a generally resilient stopper 94 is arranged, closing the passage, which stopper 94 is movable inside the body. The opposite second end of the body is preferably arranged with a neck portion 96, having a central opening. The opening of the neck portion 96 is sealed by a membrane or septum 97 of a pierceable material, FIG. 8. In the vicinity of the neck portion 96 of the medicament container 92, a piercing element 98 is arranged. The piercing element 98 comprises a generally tubular body 100, FIGS. 2, 8, arranged fixed to the proximal housing part between support walls 102, FIG. 4, and having an inner diameter somewhat larger than the diameter of the neck portion 96 of the medicament container 92. The body 100 of the piercing element 98 is arranged with a central wall 104, FIG. 8. A hollow piercing needle 106 is attached to the centre of the central wall 104. The piercing needle 106 is connected to the conduit 67 that runs to the medicament delivery member 66.

(30) Further a stop button 108 is arranged to the device. It comprises a button with the same design as the start button, FIG. 9. It is arranged to interact with a stop locking element stop 110 having the same function and design as the locking element interacting with the start button. Thus the stop button 108 is arranged with an inclined surface 112 arranged to interact with an inclined surface 114 of the stop locking element 110. The button is arranged with a shaft 116 fitting in a post 117 of the distal housing part 10. Further, the stop locking element 110 of the stop button 108 is arranged with a protrusion 118 that is designed to inter-engage with the protrusion 46 on the rotator sleeve 48 in a manner that will be described below. The stop button 108 extends through a passage in the distal housing part 12 adjacent the passage of the start button, FIG. 1. The stop button 108 may also be arranged with indicia that provide the user with information regarding its function, such as the word OFF, indicating to a user that this is the button that de-activates the device.

(31) The device further comprises a drive unit 120, FIG. 10. The drive unit 120 comprises an electric motor 122 placed inside the housing and held in place by support surfaces of the proximal housing part 10. The electric motor 122 is arranged with a drive shaft 124. A first cog wheel 126 of a transmission 128 is attached to the drive shaft 124. The first cog wheel 126 is in engagement with a second cog wheel 130 of the transmission 128, where the second cog wheel 130 is journalled in seats 132 in the proximal housing part 10. The second cog wheel 130 is in engagement with circumferentially arranged teeth 134 of a generally ring-shaped plunger rod drive wheel 136, FIG. 11. The inner surface of the plunger rod drive wheel 136 is arranged with threads 138, FIG. 11. These threads 138 are in turn arranged to be in engagement with thread segments 140 of a first plunger rod element 142. The first plunger rod element 142 has a generally rectangular shape as seen in a cross-sectional view, where the thread segments 140 are arranged in the corners of the first plunger rod element 142, as seen in FIG. 11. The proximal end of the first plunger rod element 142 is directed towards the first end of the medicament container 92, wherein the proximal end of the first plunger rod element 142 is intended to be moved in contact with the stopper 94, as will be described below. The dimensions of the first plunger rod element 142 are such that it will fit into the tubular body of the medicament container 92.

(32) The first plunger rod element 142 is arranged with two elongated grooves 144 on opposite sides thereof. These grooves 144 are intended to cooperate with guide beams 146 arranged extending from a plunger rod element holder 148. The guide beams 146 are arranged on opposite sides of a passage 150 in the plunger rod element holder 148, and the first plunger rod element 142 extends through the passage 150 in an initial position. The guide beams 146 are designed such that they have complementary shapes to, and fit into, the elongated grooves 144 of the first plunger rod element 142. Radially outwardly directed surfaces of the guide beams 146 are designed with a curved shape so as to act as support surfaces for the plunger rod drive wheel 136.

(33) The plunger rod element holder 148 is further arranged with a generally rectangularly shaped storage compartment 152, which storage compartment 152 has four side walls and extends generally perpendicularly to the passage 150. In the storage compartment 152, a number of further plunger rod elements 154 are placed. The further plunger rod elements 154 have a shape generally corresponding to the first plunger rod element 142 as seen in FIG. 12, i.e. having a generally rectangular cross-sectional shape, where the corners are provided with thread segments 156, and with longitudinal grooves 158. The further plunger rod elements 154 are arranged with first 160 and second 162 connection elements at their ends, where the first plunger rod element 142 is arranged with a first connection element 160 at its distal end. The first connection element 160 comprises a transversally arranged groove 164. The side edges of the groove 164 are arranged with inwardly directed ledges 166, where the groove 164 and each ledge 166 form a slit 168. Stop surfaces 170 are arranged at a lower end of the slits 168 as seen in FIG. 12b. A flexible tongue 172 is arranged in the groove 164, having a certain inclination as well as a wedge-shaped end protrusion 174.

(34) A further plunger rod element 154 that is placed adjacent the first plunger rod element 142 is arranged with a second connection element 162 at its end facing towards the first plunger rod element 142. The second connection element 162 comprises two proximally directed ledges 176, designed with a distance between them, generally corresponding to the width of the groove 164 of the first connection element 160. At the free ends of the ledges 176 outwardly extending protrusions 178 are arranged, which protrusions 178 have a cross-sectional shape complementary to the shape of the slits 168 such that the protrusions 178 can slide into the slits 168 when a further plunger rod element 154 is moved in a direction transversal to the longitudinal direction of the plunger rod elements, as will be described.

(35) Further, an end surface 180 of the further plunger rod element 154 between the protrusions 178 is arranged with an attachment member 182, with which the flexible tongue 172 with its wedge-shaped end protrusion 174 may engage when the plunger rod elements are connected as described. All further plunger rod elements 154 in the storage compartment 152 are arranged with the mentioned first and second connection elements 160, 162 so as to create an elongated plunger rod by the interconnected plunger rod elements. The plunger rod elements in the compartment are urged towards the passage 150 by an end piece 184, FIG. 11, placed at the top of the stack of further plunger rod elements 154 in the storage compartment 152. The end piece 184 is tensioned by a generally flat spring element 186 with one end seated in the end piece 184 and the opposite end in contact with the bottom surface 188 of the plunger rod element holder 148.

(36) The device is further arranged with a suitable power source 190, FIG. 10b, that in the embodiment shown is a battery of a generally flat and circular shape, a so called button cell. It is however to be understood that other types of power sources are feasible within the scope of the invention. For instance if the force requirement is large, then larger batteries may be needed. The poles of the battery are connected to leads where a first lead 192 is connected to a first input connector 194 of the electric motor 122. A second lead 196 runs from the battery 190 to a first contact surface 198, FIG. 10a, arranged on a side surface of the post 84. A second contact surface 200 is arranged on the side surface of the post 84 with a distance to the first contact surface 198. A third lead 202 runs from the second contact surface to a second input connector 204 of the electric motor 122. Further the drive element 74 is arranged with a conductive surface 206, FIG. 2, the function of which will be explained below.

(37) The device is intended to function as follows. When delivered to a user, it is energized in that the force element 86 is tensioned and held in that state by the drive element 74 wound around the rotator sleeve as seen in FIG. 7a, wherein the rotator sleeve 48 is held against rotating by the protrusion 44 of the start locking element 34 of the start button 16 engaging the protrusion 46 of the rotator sleeve 48 as seen in FIG. 13.

(38) When the device is to be used the lid 13 on the distal housing part 12 is opened and a medicament container 92 is placed in the interior of the device, after which the lid 13 is closed. The device is then attached to the body of the patient with suitable elements. That could for example be an adhesive on the proximal surface of the proximal housing part 10, elastic straps around the body of the patient, for example.

(39) When a user is to administer a dose of medicament, the start button is depressed. This causes the inclined surface 30 of the start button 16 to act on the inclined surface 32 of the start locking element 34, whereby the start locking element 34 is moved away from the rotator sleeve 48. This movement causes the protrusion 44 of the start locking element to move out of engagement with the protrusion 46 of the rotator sleeve 48, thus releasing the rotator sleeve 48, FIG. 14. Because of the force from the force element 84 pulling on the drive element 74, and due to the drive element 74 being wound around the outer surface of the rotator sleeve 48, the rotator sleeve 48 will rotate around the post 52. Due to the connection between the rotator sleeve 48 and the medicament delivery member holder 62 with its cylindrical protrusions 72 placed in the spiral grooves 60 of the rotator sleeve 48 and due to the rectangular protrusions 68 of the medicament delivery member holder 62 being arranged in the grooves 70 of the post 52, rotation of the rotator sleeve 48 will cause the medicament delivery member holder 62 with the medicament delivery member 66 to move in the proximal direction, causing a penetration of the tissue of the user, FIG. 15.

(40) During rotation of the rotator sleeve 48, it will come to a rotational position where the second attachment pin 78 will be pulled out of the semi-circular cut-outs 56 and will reach the seat 82 at the edge of the support wall 80 and will be held there, whereby the rotation of the rotator sleeve 48 will stop due to that the drive element 74 now is wound in the opposite direction around the rotator sleeve. However, the rotator sleeve 48 is prevented from being rotated in the opposite direction because the tongue 50 of the rotator sleeve with the protrusion 46 will, during rotation, come in contact and pass the protrusion 118 of the stop locking element 110 of the stop button 108, FIG. 16. Thus, the rotator sleeve 48 is held stationary with the force element 86 still tensioned.

(41) When the force element 86 is pulling the drive element 74, the drive element 74 will slide around the post 84. This will cause the conductive surface 206 to also be wound around the post 84 at the position where the second attachment pin is released and the rotation of the rotator sleeve stops. Now the conductive surface 206 is in contact with the two contact surfaces 198 and 200 whereby the electric circuit is closed and the electric motor 122 is activated and starts to rotate its drive shaft 124. Thus the first cogwheel 126 starts rotating and the rotation of the first cogwheel 126 is transmitted to the second cogwheel 130 of the transmission 128 and then to the plunger rod drive wheel 136 via its teeth 134. Since the threads 138 of the plunger rod drive wheel 136 are in contact with the thread segments 140 of the first plunger rod element 142, the first plunger rod element 142 is moved in the direction of the medicament container 92. When the proximal end of the first plunger rod element 142 comes in contact with the stopper 94, it will slide the medicament container 92 towards the piercing element 98 due to the incompressibility of the medicament inside the medicament container 92, FIGS. 17 and 18. The sliding of the medicament container 92 will cause the needle of the piercing element 98 to penetrate the septum 97 of the neck portion 96 of the medicament container 92, thereby creating a fluid passage between the medicament container 92 and the medicament delivery member 66, FIG. 18. Further movement of the first plunger rod element 142 will move the stopper 94 inside the medicament container 92 towards its neck portion 96, whereby medicament will be forced through the fluid connection and through the medicament delivery member 66, thereby delivering medicament to the user.

(42) When the first plunger rod element 142 has moved a distance towards and inside the medicament container 92, the space behind the first plunger rod element 142 is so large that a further plunger rod element 154 may be pushed in the vertical direction by the flat band spring element 186 acting on the uppermost positioned end piece 184 in the storage compartment 152. When the following further plunger rod elements 154 are pushed downwards in the vertical direction, they are connected to a previous plunger rod element in that the protrusions 178 of the second connection elements 162 of the further plunger rod element 154 segment fit into the slits 168 of the groove 164 of the first connection element 160 and wherein the plunger rod elements are inter-locked by the flexible tongues 172 engaging the attachment members 182. In this manner a sequential building of a continuous plunger rod is performed with the segments while performing injection of medicament from the medicament container 92 through the medicament delivery member 66.

(43) When the plunger rod has pushed the stopper 94 inside the medicament container 92 to the most proximal position, whereby the dose delivery sequence is ended, the device can be switched off. In order to do this the stop button 108 is depressed. The pushing of the stop button 108 causes its inclined surface 112 to act on the inclined surface 114 of the stop locking element 110 so that it is moved away from the protrusion 46 of the rotator sleeve 48 as seen in a radial direction, FIG. 19. This movement causes the protrusion 118 of the locking element to move out of contact with the protrusion 46 of the rotator sleeve 48, whereby the rotator sleeve 48 is released. Due to the remaining force of the force element 86, it will pull on the drive element 74, which in turn will cause the rotator sleeve 48 to rotate, however in the opposite direction due to the winding direction of the drive element 74 around the rotator sleeve 48, see arrow in FIG. 20. Because of the connection between the rotator sleeve 48 and the medicament delivery member holder 62, the spiral grooves 60 of the rotator sleeve 48 will cause the medicament delivery member holder 62 to move in the distal direction, causing a withdrawal of the medicament delivery member 66 from the body of the user. At the same time, the conductive surface 206 of the drive element 74 is moved from the contact surfaces of the post, FIG. 22, whereby the electric motor 122 is stopped. The medicament delivery device can now be removed from the body and recharged or discarded.

(44) It is to be understood that the embodiment described above and shown in the drawings is to be regarded only as a non-limiting example of the invention and that it may be modified in many ways within the scope of the patent claims.

COMPONENT LIST

(45) 10 proximal housing part 12 distal housing part 13 lid 14 activation mechanism 16 start button 18 passage 20 tubular body 22 end wall 24 shaft 26 guide post 28 cut-out 30 side surface 32 inclined surface 34 start locking element 36 seat portion 38 post 40 flexible arm 42 post 44 protrusion 46 protrusion 48 driver, rotator sleeve 50 tongue 52 post 54 tongue 56 cut-out 58 hole 60 spiral groove 62 medicament delivery member holder 64 wall 66 medicament delivery member 67 conduit 68 rectangular protrusion 70 groove 72 cylindrical protrusion 74 drive element 76 first attachment pin 78 second attachment pin 80 support wall 82 seat 84 post 86 force element 88 spring hub 90 post 92 medicament container 94 stopper 96 neck portion 97 septum 98 piercing element 100 body 102 support wall 104 central wall 106 piercing needle 108 stop button 110 stop locking element 112 inclined surface 114 inclined surface 116 shaft 117 post 118 protrusion 120 drive unit 122 electric motor 124 drive shaft 126 first cog wheel 128 transmission 130 second cog wheel 132 seat 134 teeth 136 plunger rod drive wheel 138 threads 140 thread segment 142 first plunger rod element 144 groove 146 guide beam 148 plunger rod element holder 150 passage 152 storage compartment 154 further plunger rod element 156 thread segment 158 groove 160 first connection 162 second connection 164 groove 166 ledge 168 slit 170 stop surface 172 flexible tongue 174 wedge-shaped protrusion 176 ledge 178 protrusion 180 end surface 182 attachment member 184 end piece 186 spring element 188 bottom surface 190 power source, battery 192 first lead 194 first input connector 196 second lead 198 first contact surface 200 second contact surface 202 third lead 204 second input connector 206 conductive surface