Cosmetic preparation comprising pulverized hydrophobic substances

Abstract

A substance, which is in principle insoluble in a cosmetic or dermatological preparation, is converted into a powdery product by absorption onto a carrier, wherein said powdery product can be distributed better in the preparation. The preparations comprise water and one or more hydrophobic substances or substance mixtures which are liquid and pasty at room temperature and/or meltable up to a temperature of 150 C. and which are absorbed on one or more particulate carriers. The hydrophobic substance or substance mixture in itself is insoluble or sparingly soluble in the preparation and the carriers are characterized by a particle size ranging from 5 nm to 2 mm, a tamped density of between 50 kg/m.sup.3 and 1400 kg/m.sup.3 and a spherical, fibrous, flocculated and/or sponge-like particulate form.

Claims

1. A cosmetic or dermatological preparation, wherein the preparation is present in the form of a packaged product which comprises water and, incorporated therein, one or more powdery materials comprising or consisting of (i) one or more hydrophobic substances or substance mixtures which comprise one or more of ubiquinone, thymol, and oryzanol, are liquid or pasty at room temperature and/or meltable up to a temperature of 150 C. and on their own are insoluble or sparingly soluble in a remainder of the preparation, bound by at least one of adhesion, impregnation, agglomeration to (ii) one or more particulate carriers having an average particle size in a range of from 5 nm to 2 mm and a tamped density of from 50 kg/m.sup.3 to 1400 kg/m.sup.3, and being of a spherical, fibrous, flocculated and/or sponge-like form.

2. A cosmetic or dermatological preparation, wherein the preparation is present in the form of a packaged product which comprises water and, incorporated therein, one or more powdery materials comprising or consisting of (i) one or more hydrophobic substances or substance mixtures which comprise at least one of farnesol and dimethyl phenyl butanol, are liquid or pasty at room temperature and/or meltable up to a temperature of 150 C. and on their own are insoluble or sparingly soluble in a remainder of the preparation, bound by at least one of adhesion, impregnation, agglomeration to (ii) one or more particulate carriers having an average particle size in a range of from 5 nm to 2 mm and a tamped density of from 50 kg/m.sup.3 to 1400 kg/m.sup.3, and being of a spherical, fibrous, flocculated and/or sponge-like form.

3. A cosmetic or dermatological preparation, wherein the preparation is present in the form of a packaged product which comprises water and, incorporated therein, one or more powdery materials comprising or consisting of (i) one or more hydrophobic substances or substance mixtures which comprise at least one oil-soluble UV filter, are liquid or pasty at room temperature and/or meltable up to a temperature of 150 C. and on their own are insoluble or sparingly soluble in a remainder of the preparation, bound by at least one of adhesion, impregnation, agglomeration to (ii) one or more particulate carriers having an average particle size in a range of from 5 nm to 2 mm and a tamped density of from 50 kg/m.sup.3 to 1400 kg/m.sup.3, and being of a spherical, fibrous, flocculated and/or sponge-like form.

4. The preparation of claim 3, wherein the at least one oil-soluble UV filter comprises at least one of butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

5. The preparation of claim 3, wherein (i) has been bound to (ii) by a Concentrated Powder Form (CPF) process.

6. The preparation of claim 3, wherein (ii) comprises a polysaccharide.

7. The preparation of claim 6, wherein (ii) comprises cellulose and/or a cellulose derivative.

8. The preparation of claim 6, wherein (ii) comprises a starch.

9. The preparation of claim 3, wherein (ii) comprises one or more of silica and a silicate.

10. The preparation of claim 3, wherein (ii) comprises one or more of a nylon and lauroyl lysine.

11. The preparation of claim 3, wherein the one or more powdery materials consist of (i) and (ii).

12. The preparation of claim 3, wherein the one or more powdery materials are free of emulsifiers and stabilizers.

Description

DETAILED DESCRIPTION OF THE INVENTION

(1) The carrier substances are powder substances customarily used in cosmetics. They are preferably selected from the group of polysaccharides and silicas and derivatives thereof; powder substances as are used in decorative cosmetics as filler and sensory additive are also possible. The list below of carrier materials that can be used advantageously should in no way be limiting:

(2) Polysaccharides: starches from different plant sources, e.g. corn starch, potato starch, rice starch, wheat starch, and derivatives thereof (e.g. trade names: Amylogum CLS from Avebe, C*EmCap from Cerestar, DryFlo grades from Akzo Nobel celluloses and derivatives, e.g. Avicel grades from FMC Biopolymer, Arbocel, Vitacel, Vivapur grades from J. Rettenmaier & Shne GmbH.

(3) Further fillers such as lauroyl lysine (Amihope LL), nylon grades (e.g. Orgasol grades from Arkema) or silicates such as calcium silicate (Hubersorb from Huber) can be used. In the case of the silicas, preferably grades from the series of Aerosils from Evonik Degussa can be used.

(4) The powdery products include the hydrophobic substances or substance mixtures (a.) and the particulate carriers (b.) on which they are absorbed, or preferably they consist only of these two constituents a.) and b.).

(5) It is possible to dispense with the addition of emulsifiers or stabilizers in the powdery products.

(6) A further preferred criterion is that the powdery products are produced according to the CPF process.

(7) According to the invention, the hydrophobic substance or the substance mixture is characterized in that, by itself, it is insoluble or sparingly soluble in the preparation. Here, a hydrophobic substance or a hydrophobic substance mixture is characterized in that it is immiscible with water. Solubility is the property of a substance to dissolve homogeneously in a liquid or melt.

(8) As a result of pulverizing the hydrophilic substances or substance mixtures, also referred to as active ingredients or active solutions, it is now possible according to the invention to incorporate these without further auxiliaries such as solubility promoters or emulsifiers into formulations in which they are not soluble in a homogeneous manner, i.e. without phase separation.

(9) I.e. a substance that is in principle insoluble in a cosmetic or dermatological preparation is converted to a powdery product as a result of absorption on a carrier and homogeneously distributed in the preparation, where the substance insoluble in the hydrophilic formulation is bonded as hydrophobic solution to the carrier. The powder laden with active ingredients does not dissolve here in the preparation, but is present in the formulation such as a sensory additive as powder, only additionally laden with liquid.

(10) Pulverization advantageously takes place according to the CPF process. Reference is hereby expressly made to the CPF processes described in documents WO 99 17868 A1, EP 1 021 241 A1 and EP 0 744 992 A1. The disclosures made therein are in their entirety also part of the present application.

(11) The CPF process makes it possible to produce powdery solids from liquids. The process principle consists in dissolving a gas in the liquid to be pulverized under elevated pressure, preferably until a gas-saturated solution is obtained. Compared to pure liquid, such a solution has a series of favorable properties:

(12) Thus, normally, the viscosity of this solution is lowered by several orders of magnitude compared to the pure liquid at the same temperature, and the interfacial tension is also considerably reduced.

(13) The pressurized liquid/gas solution is then fed to a decompression element and rapidly decompressed therein. Before the decompression element, in the decompression element or after it, in particular shortly after the decompression element, a solid, powdery auxiliary, the particulate carrier, is admixed with the liquid substance or substance mixture to be pulverized or the liquid/gas solution.

(14) The gas used can in principle be any gas which is sufficiently soluble in the liquid substance or substance mixture to be pulverized. For example, the gas that can be used is carbon dioxide, a hydrocarbon, in particular methane, ethane, propane, butane, ethene, propene or a halogenated hydrocarbon, an ether, an inert gas, in particular nitrogen, helium or argon, a gaseous oxide, in particular dinitrogen oxide or sulfur dioxide, and ammonia. A mixture of two or more of the aforementioned gases can also be used. The increased pressure under which the gas is dissolved in the liquid substance or substance mixture can be in the range from 5 bar to 800 bar, although preferably the pressure is in the range from 10 bar to 350 bar and particularly preferably in the range from 20 bar to 250 bar.

(15) Preferably, the dissolution of the gas in the liquid substance or substance mixture is accelerated by mixing the gas with the liquid substance or substance mixture. This mixing can be achieved for example by shaking or rolling the pressurized container in which the liquid to be pulverized has been introduced. Alternatively, the solution that is formed in the pressurized container can be stirred using a stirrer. Another option of achieving thorough mixing of the liquid to be pulverized with the gas consists in recirculating the liquid phase present in the pressurized container and/or the gas phase, i.e. pumping it/them from the pressurized container and introducing it/them again to the pressurized container in the region of the respective other phase. A further option is the use of a static mixer. The aforementioned procedures can of course also be combined.

(16) The CPF process functions in principle with any solid, powdery carrier.

(17) The substance to be pulverized, the active solution, is bound here to the carrier particle by adhesion, impregnation and/or agglomeration. Surprisingly, the CPF process does not lead to a closed envelope being formed. Capsules are not formed. Consequently, the hydrophobic active solution can detach from the particulate carrier as soon as the laden particles come into an environment in which the active solution is soluble and/or to which there exists an affinity. Thus, for example, the hydrophobic substances can bind with the skin sebum on the skin and thus attach to the skin. The release then takes place also with a time delay and thus leads to a long-lasting effect.

(18) On account of the special production technology with CPF technology, the substance, active ingredient on the particles is already present in predissolved form at the site of action and can be very rapidly released. The thus improved solubility is comparable with that of instant coffee compared to coffee powder.

(19) According to the invention, hydrophobic substance, substance mixture, active ingredient or active solution to be pulverized are to be understood as meaning all substances that are liquid or pasty at room temperature and/or meltable up to a temperature of 150 C.

(20) The active solution is preferably liquid at room temperature, but can also be pasty to solid if it is then meltable at a temperature up to 150 C.

(21) Preferred cosmetic active ingredients which can be present in the preparation and are preferably pulverized by means of CPF are to be selected from the group of antibacterial, antiperspirant, anti-aging, skin-calming and/or moisturizing active ingredients.

(22) Deodorant active ingredients such as farnesol, dimethyl phenyl butanol or other active ingredients, such as ubiquinone, thymol or oryzanol, can likewise be selected. Furthermore, oil-soluble UV filters can be used, e.g. Butyl Methoxydibenzoylmethane or Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine.

(23) Further active ingredients can be selected from the group of extracts, such as e.g. of/from Persea Gratissima, Fucus Vesiculosas, Hamamelis Virginiana, Chamomilla Recutita flower extract, cotton seed oil, Simmondsia Chinensis (jojoba) oil, menthol, Glycyrrhiza Glabra.

(24) According to the invention, now hydrophobic deodorant actives can for example be incorporated into water-containing formulations.

(25) The substances, active ingredients or active solutions to be incorporated are insoluble or only sparingly soluble in the preparation. The solubility is the property of a substance to dissolve homogeneously in a liquid. Substance or substance mixtures which cannot dissolve completely in the solvent or can only dissolve inhomogeneously in solvents are referred to as insoluble or sparingly soluble, respectively.

(26) The cosmetic and dermatological preparations according to the invention can also comprise cosmetic auxiliaries and further active ingredients, as are customarily used in such preparations, e.g. preservatives, preservation aids, bactericides, perfumes, substances for preventing foaming, dyes and colored pigments, thickeners, moisturizing and/or humectant substances, fats, oils, waxes or other customary constituents of a cosmetic or dermatological formulation, such as alcohols, polyols, polymers, foam stabilizers, electrolytes, organic solvents or silicone derivatives, provided the addition does not adversely affect the required properties as regards solubility.