"Bowl-of-Spaghetti" Type Intrasacular Aneurysm Occlusion Device
20200100795 ยท 2020-04-02
Assignee
Inventors
Cpc classification
A61B2017/12054
HUMAN NECESSITIES
A61B2017/1209
HUMAN NECESSITIES
A61B2017/12077
HUMAN NECESSITIES
A61B2017/00292
HUMAN NECESSITIES
A61B17/1215
HUMAN NECESSITIES
International classification
Abstract
This invention is a bowl-of-spaghetti type intrasacular aneurysm occlusion device including: a catheter; embolic coils; a bowl or cup shaped neck bridge; an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. It is a called a bowl-of-spaghetti type device because the neck bridge can look like a bowl and the embolic coils can look like spaghetti noodles in the bowl.
Claims
1. A bowl-of-spaghetti type intrasacular aneurysm occlusion device comprising: a longitudinal lumen which is configured into be inserted into a person's vasculature; one or more longitudinal embolic members which are configured to be delivered through the longitudinal lumen into an aneurysm sac in the person's vasculature; an expandable proximal member which is configured to be inserted into and expanded within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac.
2. The device in claim 1 wherein the longitudinal lumen is a catheter, the longitudinal embolic members are embolic coils, and the expandable proximal member is a neck bridge.
3. The device in claim 1 wherein the expandable proximal member self expands within the aneurysm sac.
4. The device in claim 1 wherein the expandable proximal member expands into an upward-opening-convex shape.
5. The device in claim 1 wherein the expandable proximal member expands into a bowl or cup shape.
6. The device in claim 1 wherein the expandable proximal member is a neck bridge.
7. The device in claim 6 wherein the neck bridge is a braided or woven stent, lattice, mesh, and/or framework.
8. The device in claim 6 wherein the neck bridge is a 3D printed stent, lattice, mesh, and/or framework.
9. The device in claim 6 wherein the neck bridge is a multi-layer neck bridge which is made by folding and/or compressing a generally spherical or ellipsoidal stent, lattice, mesh, or framework into a multi-layer bowl or cup shaped stent, lattice, mesh, or framework.
10. The device in claim 6 wherein the neck bridge is a multi-layer neck bridge which is made by folding and/or compressing a generally spherical or ellipsoidal stent, lattice, mesh, or framework within the aneurysm sac.
11. The device in claim 6 wherein the neck bridge is a multi-layer neck bridge which is made by folding, twisting, and/or inverting a generally tubular stent, lattice, mesh, or framework into a multi-layer bowl or cup shaped stent, lattice, mesh, or framework.
12. The device in claim 1 wherein the expandable proximal member expands to a diameter which is at least 10% larger than the maximum diameter of the aneurysm neck.
13. The device in claim 1 wherein the expandable proximal member expands to a diameter which is at least 85% of the maximum diameter of the aneurysm sac.
14. The device in claim 1 wherein the expandable proximal member expands to a diameter which is at least 10% larger than the maximum diameter of the aneurysm neck and at least 85% of the maximum diameter of the aneurysm sac.
15. The device in claim 1 wherein the longitudinal lumen connects to and/or protrudes into the opening in the expandable proximal member.
16. The device in claim 1 wherein the closure mechanism is remotely-activated by the application of electromagnetic energy.
17. The device in claim 1 wherein the closure mechanism closes the opening in the expandable proximal member and detaches an embolic longitudinal member which has been inserted into the aneurysm sac.
18. The device in claim 1 wherein the closure mechanism closes the opening in the expandable proximal member, detaches an embolic longitudinal member which has been inserted into the aneurysm sac, and detaches the longitudinal lumen from the expandable proximal member so that the longitudinal lumen can be withdrawn from the person's vasculature.
19. A bowl-of-spaghetti type intrasacular aneurysm occlusion device comprising: a catheter which is inserted into a person's vasculature; one or more embolic coils which are delivered through the catheter into an aneurysm sac; a neck bridge which expands into a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
20. A bowl-of-spaghetti type method of occluding an aneurysm comprising: inserting a catheter into a person's vasculature; inserting a neck bridge on or through the catheter into an aneurysm sac in the person's vasculature; expanding the neck bridge into a bowl or cup shape within the aneurysm sac, wherein the neck bridge is expanded to a diameter which is larger than the maximum diameter of the aneurysm neck; inserting one or more embolic coils into the aneurysm through the catheter and through an opening in the neck bridge; closing the opening in the neck bridge; and withdrawing the catheter from the person's vasculature.
Description
BRIEF INTRODUCTION TO THE FIGURES
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[0050]
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DETAILED DESCRIPTION OF THE FIGURES
[0053] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: a longitudinal lumen (e.g. a catheter) which is configured into be inserted into a person's vasculature; one or more longitudinal embolic members (e.g. coils) which are configured to be delivered through the longitudinal lumen into an aneurysm sac in the person's vasculature; an expandable proximal member (e.g. a bowl-shaped neck bridge) which is configured to be inserted and expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member spans the aneurysm neck; an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac. This is a called bowl-of-spaghetti device because, from a lateral perspective, the expandable proximal member looks like a bowl and the plurality of longitudinal embolic members look like spaghetti noodles in the bowl.
[0054] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can also be described as comprising: a catheter which is inserted into a person's vasculature; coils which are delivered through the catheter into an aneurysm sac; a bowl-shaped neck bridge which self-expands within a proximal portion the aneurysm sac to a diameter which is larger than the aneurysm neck; an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0055]
[0056]
[0057] With respect to specific components,
[0058] The example shown in
[0059] In this example, the longitudinal lumen is configured to be inserted into a blood vessel, wherein this blood vessel is the parent vessel from which an aneurysm has formed. The longitudinal embolic members are configured to travel through the longitudinal lumen and be inserted into the aneurysm sac. The expandable proximal member is configured to travel through the longitudinal lumen, be inserted into the aneurysm sac, and self expand within the aneurysm sac. The expandable proximal member is configured to substantially occlude the aneurysm neck after it is expanded. The longitudinal embolic members are inserted into the aneurysm sac through a central opening of the expandable proximal member. The expandable proximal member prevents the longitudinal flexible members from protruding into the parent vessel of the aneurysm. In this example, the expandable proximal member is a mesh. In this example, the closure mechanism is a cord. In this example, pulling a cord detaches loops which hold an elastic ring in the expandable proximal member open, thereby closing the opening in the proximal expandable member.
[0060] In an example, a longitudinal lumen can be a removable catheter. In an example, a longitudinal lumen can be configured to be inserted into a blood vessel from which an aneurysm sac has formed. In an example, one or more longitudinal embolic members can be embolic coils. In an example, a longitudinal embolic member can be configured to travel through a longitudinal lumen and inserted into an aneurysm sac. In an example, the function of this device can be described as aneurysm coil jailing using an expandable proximal member. The expandable proximal member prevents the one or more longitudinal flexible members (e.g. coils) from protruding into the parent vessel of an aneurysm. In an example, an expandable proximal member can be an expandable intrasacular mesh, braid, lattice, or framework. In an example, an expandable proximal member can be toroidal. In an example, an expandable proximal member can be an expandable (toroidal) proximal member that is configured to be inserted into and expanded within aneurysm sac. In an example, an expandable (toroidal) proximal member can remain in the aneurysm sac after implantation of the device.
[0061] In an example, an expandable proximal member can self expand after it is inserted into an aneurysm sac. In an example, an expandable (toroidal) proximal member can self expand because it comprises shape memory material. In an example, an expandable proximal member can comprise a mesh, network, lattice, or radial array of wires or other stiff fibers. In an example, an expandable proximal member can be reinforced with wires or other stiff fibers. In an example, an expandable proximal member can be made from metal, a polymer, or both. In an example, an expandable proximal member can be made with nitinol (or other nickel titanium alloy), cobalt-chrome alloy (cobalt chromium), gold, palladium, platinum, steel (e.g. stainless steel), tantalum, titanium, and/or tungsten.
[0062] In an example, an expandable proximal member can expand in a radial-expansion plane that is substantively parallel with the plane defined by a central circumference of an aneurysm neck. In an example, an expandable proximal member can be expanded at a distance from a central circumference of an aneurysm neck from which its radial expansion contacts the aneurysm sac at the sac's maximum circumference. In an example, an expandable proximal member can be expanded at a distance from a central circumference of the aneurysm neck from which its radial expansion contacts the aneurysm sac at a sac circumference that is greater than the central circumference of the aneurysm neck. In an example, an expandable proximal member can function as an intrasacular stent or neck bridge.
[0063] In an example, an expandable proximal member can have a toroidal shape, bowl shape, convex lens shape, cup shape, paraboloid (of revolution) shape, inverted umbrella shape, or hemispherical shape. In an example, an expandable proximal member can have an annular shape, cylindrical shape doughnut shape, ring shape, tire shape, or wheel shape. In an example, an expandable proximal member can have a disk shape. In an example, an expandable proximal member can have a dome shape. In an example, an expandable proximal member can be a spherical stent which has been collapsed into a hemispherical shape. In an example, an expandable proximal member can comprise a spherical stent which is collapsed into a hemisphere in order to create a double-layer barrier near an aneurysm neck.
[0064] In an example, an expandable proximal member can have an adjustable opening through which one or more embolic members are inserted into an aneurysm sac. In an example, one or more longitudinal embolic members can be inserted into an aneurysm sac through an opening in a expandable proximal member after the expandable proximal member has been expanded within an aneurysm sac. In an example, a plurality of embolic members can be inserted into an aneurysm sac through a central opening in an expandable proximal member and the expandable proximal member can have a sufficiently tight fit with the aneurysm walls that none of the embolic members escape into the parent blood vessel. In an example, embolic members can be inserted into an aneurysm sac through a one-way valve in a hole (e.g. opening) in an expandable proximal member.
[0065] In an example, an expandable proximal member can further comprise an opening through which embolic members are introduced into the enclosure and a closure mechanism, associated with the opening, wherein the closure mechanism is configured to be actuated to reduce a size of the opening. In an example, a hole (e.g. opening) in an expandable proximal member can be closed after an aneurysm sac has been filled with embolic members inserted through the hole. In an example, a closure mechanism can be integrated into an expandable proximal member to prevent embolic members from escaping through the opening by which they were inserted into the expandable proximal member. In an example, a closure mechanism can be remotely actuated by a device user to reduce a size of the opening. In an example, a closure mechanism can comprise a one-way valve that automatically lets embolic members into the aneurysm sac, but does not let them out. In an example, a closure mechanism can include a cord which is pulled from a remote location outside the body to detach an expandable proximal member from a catheter and close an opening in the expandable proximal member.
[0066] In an example, a closure mechanism can be selected from the group consisting of: drawstring, elastic ring, loop, and tie-off. In an example, a closure mechanism can be a pull cord or wire. In an example, a closure mechanism can be a plug or valve. In an example, a closure mechanism can be selected from the group consisting of: adhesive, electromagnetic energy, fusible member, and fusion. In an example, a closure mechanism can be selected from the group consisting of: clasp, clip, shape-memory material, and snap. In an example, a closure mechanism can be selected from the group consisting of: cap, seal, and threaded member.
[0067] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (b) an inflatable toroidal neck bridge which is expanded to a diameter which is larger than the diameter of the aneurysm neck; (e) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (f) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In an alternative example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided multi-layer neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0068] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is at least 20% larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided Nitinol neck bridge (e.g. stent, framework, lattice, or mesh) which is inserted into the aneurysm sac in a first shape, then is expanded (e.g. self-expands) within the aneurysm sac into an ellipsoidal second shape, and then is compressed and/or folded into a bowl or cup third shape with a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0069] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided, knitted, or woven neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is at least 90% of the maximum diameter of the aneurysm sac in a plane which is parallel to the plane of the aneurysm neck; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a double-layer neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a hemispherical shape within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge is created by compressing a spherical mesh into a double-layer hemispherical mesh; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0070] In an example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a multi-layer neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck, wherein the multi-layer neck bridge is made from a tubular braid which is tied (or twisted or otherwise radially constrained) at a selected location along the length of the tube and then inverted (or folded or everted) over itself relative to that selected location; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0071] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a multi-layer, upward-facing-convex neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) made with nitinol cobalt chromium which expands (e.g. self-expands) into a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0072] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding into a bowl or cup shape with a diameter which is larger than the diameter of the aneurysm neck, wherein the proximal half of the neck bridge has a first porosity level, wherein the distal half of the neck bridge has a second porosity level, and wherein the second porosity level is greater than the first porosity level; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck, wherein the neck bridge further comprises at least one radiopaque marker; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0073] In an example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac at a location from which it contacts the aneurysm sac at a sac circumference that is greater than the central circumference of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0074] In an example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) into a hemispherical shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac, wherein the coils have an average first cross-sectional area; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac, wherein the opening has a second cross-sectional area when open and a third cross-sectional area when closed, wherein the second cross-sectional area is at least 10% greater than the first cross-sectional area, and wherein the first cross-sectional area is at least 10% greater than the third cross-sectional area; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0075] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises an electromagnetic actuator. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to an inverted umbrella shape within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0076] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are transported through the catheter and inserted into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which is transported through the catheter in a radially-more-constrained first configuration, inserted into the aneurysm sac, and then expanded (e.g. self expanded) from the first configuration to a radially-less-constrained second hemispherical configuration, wherein the second configuration has a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0077] In an example, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a hydrogel closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In yet another embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a tensile ring which closes the opening after the coils have been inserted into the aneurysm sac.
[0078] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an electromagnetic closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a non-central opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0079] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a opening in the outer (e.g. peripheral) half of the cross-sectional area neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an elastic-ring opening in the neck bridge through which the catheter protrudes and through which coils are inserted into the aneurysm sac, wherein the elastic-ring closes when the catheter is removed from the opening.
[0080] In an example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in base of the neck bridge through which the coils are inserted into the aneurysm sac; (e) an electromagnetic detachment and closure mechanism which detaches one or more segment of embolic coils and closes the opening so that the segments do not escape out of the aneurysm sac. In an alternative example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter extends and through which coils are inserted into the aneurysm sac; and (e) a closure mechanism which detaches a segment of embolic coil, withdraws the catheter from the opening, and closes the opening.
[0081] A bowl-of-spaghetti type intrasacular aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter extends and through which coils are inserted into the aneurysm sac; and (e) one or more closure mechanisms which detach one or more embolic coils, withdraw the catheter from the opening, and close the opening after the aneurysm sac has been filled with one or more embolic coils. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0082] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, wherein neck of the aneurysm has a maximum diameter with a first length, wherein the aneurysm sac has a maximum diameter (in a plane which is parallel to the plane of the aneurysm neck) with a second length, wherein the neck bridge is expanded within the aneurysm sac to a third diameter with a third length, wherein the third length is greater than 120% of the first length, and wherein the third length is greater than 80% of the second length; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0083] In one possible embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is at least 10% larger than the diameter of the aneurysm neck; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a remotely-activated closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) with a helical wire which expands (e.g. self-expands) into a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0084] In an example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a Nitinol neck bridge (e.g. stent, framework, lattice, or mesh) which is inserted into the aneurysm sac in a first shape, then expanded (e.g. self-expands) within the aneurysm sac into an ellipsoidal second shape, and then compressed and/or folded into a bowl or cup third shape with a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a shaped neck bridge (e.g. stent, lattice, mesh, or framework) which is inserted into the aneurysm sac, is expanded (e.g. self-expands) into a substantially spherical shape within the aneurysm sac, and then is collapsed into a double-layer, upward-opening, bowl shape which substantially covers the inside of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0085] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a upwardly-concave neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a longitudinal lumen (e.g. a catheter); (b) one or more longitudinal embolic members (e.g. embolic coils) which are inserted into an aneurysm sac; (c) an expandable proximal member (e.g. a bowl or cup shaped neck bridge) which is expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck; (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac.
[0086] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a longitudinal lumen (e.g. a catheter); (b) one or more longitudinal embolic members (e.g. embolic coils) which are inserted into an aneurysm sac; (c) an expandable proximal member (e.g. an upward-opening convex stent) which is expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck; (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the expandable proximal member through which the coils are inserted into the aneurysm sac; (e) an electrical coil detachment (e.g. cutting) mechanism which detaches (e.g. cuts) one or more segments of embolic coils after a portion of the embolic coils has been inserted into the aneurysm sac; and (f) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0087] In an embodiment, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member is a spherical stent which has been collapsed or folded into a double-layer hemispherical shape; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In yet another embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism is a rotatable closure mechanism.
[0088] A bowl-of-spaghetti type aneurysm occlusion device can alternatively comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism comprises electromagnetic energy which is applied to the opening. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises expansion of a hydrogel.
[0089] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a spring or elastic member with a first configuration which does not block (or otherwise close) the opening and a second configuration which blocks (or otherwise closes) the opening, wherein the spring or elastic member is changed from its first configuration to its second configuration by stopping the transmission of electromagnetic energy.
[0090] A bowl-of-spaghetti type intrasacular aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism is closed by the transmission of electrical energy to it. Alternatively, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) to an inverted dome shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0091] In an embodiment, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac so as to completely cover the inside of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which reduces the size of the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a remotely-controlled (one-way) valve with a first configuration allows coils to be inserted through the opening into the aneurysm sac, but does not allow coils to escape out of the aneurysm sac, and a second configuration which allows coils to be pulled out of the aneurysm sac.
[0092] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an upward-facing-convex neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In an alternative example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an upward-facing-convex neck bridge self-expands within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge is made from nitinol (or other nickel titanium alloy), cobalt-chrome alloy (cobalt chromium), gold, palladium, platinum, steel (e.g. stainless steel), tantalum, titanium, and/or tungsten; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0093] In an example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) allowing the neck bridge to self-expand into a spherical or ellipsoidal first shape; (c) axially contracting, compressing, and/or folding the neck bridge from the first shape into a double-layer bowl or cup second shape; (d) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (e) closing the opening in the neck bridge. In another example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the aneurysm sac into a hemispherical shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge.
[0094] In an example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the proximal half of the aneurysm sac into a convex shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. Alternatively, a aneurysm occlusion method can be embodied in: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge into a bowl or cup shape with a diameter which is between 90% and 100% of the maximum diameter of the aneurysm sac; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. In another example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) releasing the neck bridge to self expand into a bowl or cup shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and then (d) closing the opening in the neck bridge.
[0095] In an embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a 3D-printed neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0096] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided, knitted, or woven neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0097] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a cross-sectionally-asymmetric neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) to a disk shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; (e) a coil detachment (e.g. cutting) mechanism which detaches (e.g. cuts) one or more segments of embolic coils after a portion of the embolic coils has been inserted into the aneurysm sac; and (f) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0098] In an example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a multi-layer, arcuate neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an electromagnetic closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a multi-layer, upward-facing-convex neck bridge (e.g. stent, lattice, mesh, or framework) which is expanded within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0099] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the catheter extends and through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which retracts the catheter from the opening and closes the opening after the coils have been inserted into the aneurysm sac.
[0100] A bowl-of-spaghetti type intrasacular aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding into a bowl or cup shape with a diameter which is larger than the diameter of the aneurysm neck, wherein the proximal half of the neck bridge has a first mesh density, wherein the distal half of the neck bridge has a second mesh density, and wherein the second mesh density is less than the first mesh density; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0101] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck, wherein the neck bridge further comprises a radiopaque marker at its proximal end; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which self-expands into a barrel shape within the aneurysm sac, wherein we all have fun when the barrel is rolled out, with due credit to the Andrews Sisters; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0102] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self expands) to a bowl or cup shaped within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck, but smaller than the maximum diameter of the aneurysm sac; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0103] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In an alternative example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a MEMS actuator.
[0104] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are transported through the catheter and inserted into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which is transported through the catheter in a radially-more-constrained first configuration, inserted into the aneurysm sac, and then expanded (e.g. self expanded) into a radially-less-constrained second configuration, wherein the second configuration has a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are transported through the catheter and inserted into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which is transported through the catheter in a radially-more-constrained first configuration, inserted into the aneurysm sac, and then expanded (e.g. self expanded) from the first configuration to a radially-less-constrained second disk-shaped configuration, wherein the second configuration has a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0105] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a magnetic closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an adhesive closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0106] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an electromagnetic closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism is remotely-activated by a device user. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a non-central opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0107] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a plurality of non-central openings in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) one or more closure mechanisms which close the plurality of openings after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an off-center opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0108] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in base of the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In an alternative example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter extends and through which coils are inserted into the aneurysm sac; and (e) a closure mechanism which detaches an embolic coil, withdraws the catheter from the opening, and closes the opening.
[0109] In an example, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter protrudes and through which the coils are inserted into the aneurysm sac, wherein the opening automatically closes when the catheter is removed from the opening. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a first diameter, wherein the aneurysm neck has a second diameter, wherein the aneurysm sac has a maximum third diameter in a plane which is parallel to the aneurysm neck, and wherein the first diameter is at least 110% of the second diameter and at least 70% of the third diameter; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0110] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, wherein neck of the aneurysm has a maximum diameter with a first length, wherein the aneurysm sac as maximum diameter (in a plane which is parallel to the plane of the aneurysm neck) with a second length, wherein the neck bridge is expanded within the aneurysm sac to a third diameter with a third length, wherein the third length is greater than 110% of the first length, and wherein the third length is greater than 90% of the second length; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is at least 20% larger than the diameter of the aneurysm neck; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a remotely-activated closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0111] In an embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) with a radially-more-constrained first configuration and a radially-less-constrained second configuration, wherein the neck bridge is inserted into the aneurysm sac in its first configuration and self-expands into its second configuration; wherein the neck bridge has a bowl, cup, hemispherical, and/or paraboloidal shape in its second configuration; and wherein the neck bridge has a diameter which is greater than the diameter of the aneurysm neck in its second configuration; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0112] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a paraboloid-shaped neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a shaped neck bridge (e.g. stent, lattice, mesh, or framework) which is inserted into the aneurysm sac, is expanded (e.g. self-expands) into a substantially ellipsoidal shape within the aneurysm sac, and then is collapsed into a double-layer, upward-opening, bowl shape which substantially covers the inside of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0113] In one possible embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a upwardly-convex neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0114] In an embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a longitudinal lumen (e.g. a catheter) which is configured into be inserted into a person's vasculature; (b) one or more longitudinal embolic members (e.g. embolic coils) which are configured to be delivered through the longitudinal lumen into an aneurysm sac; (c) an expandable proximal member (e.g. a bowl or cup shaped neck bridge) which is configured to be inserted and expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member spans the aneurysm neck; and (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac.
[0115] A bowl-of-spaghetti type aneurysm occlusion device can alternatively comprise: (a) a longitudinal lumen (e.g. a catheter) which is configured into be inserted into a person's vasculature; (b) one or more longitudinal embolic members (e.g. embolic coils) which are configured to be delivered through the longitudinal lumen into an aneurysm sac; (c) an expandable proximal member (e.g. an upward-opening-convex neck bridge) which is configured to be inserted and expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member spans the aneurysm neck; (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac. In yet another embodiment, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) to a disk shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the expandable proximal member through which the coils are inserted into the aneurysm sac; (e) an electromagnetic coil detachment (e.g. cutting) mechanism which detaches (e.g. cuts) one or more segments of embolic coils after a portion of the embolic coils has been inserted into the aneurysm sac; and (f) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0116] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member is a tubular stent which has been inverted (or everted) into a double-layer convex shape; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprise a rotatable wire or catheter which is remotely rotated by a device user.
[0117] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism comprises electromagnetic energy which is applied to fuse opening closed. Alternatively, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism is a cap, seal, and/or threaded member.
[0118] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a spring or elastic member with a first configuration which does not block (or otherwise close) the opening and a second configuration which blocks (or otherwise closes) the opening, wherein the spring or elastic member is changed from its first configuration to its second configuration by transmitting a pulse of electrical current to it. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0119] In an example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which reduces the size of the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, conforming to the walls of the most proximal one-third of the aneurysm sac; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which reduces the size of the opening after the coils have been inserted into the aneurysm sac.
[0120] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a non-central opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an upward-facing-convex neck bridge (e.g. stent, lattice, mesh, or framework) which self-expands within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge further comprises a mesh, network, lattice, or radial array of wires or other stiff fibers; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0121] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an upward-opening convex neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge is created by tying (or otherwise radially-constraining) and then inverting a portion of a tubular mesh; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type method for occluding an aneurysm can be embodied in: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the aneurysm sac into a paraboloidal shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through a central opening in the neck bridge; and (d) closing the opening in the neck bridge.
[0122] In an example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the aneurysm sac of the into a convex shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. In another example, a aneurysm occlusion method can comprise: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the proximal half of the aneurysm sac into a hemispherical shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge.
[0123] In an example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge into a bowl or cup shape with a diameter which is at least 20% wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. In an alternative example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a 3D-printed neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is at least 20% larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0124] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is at least 20% larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is at least 20% larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0125] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided, knitted, or woven neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a cross-sectionally-asymmetric neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0126] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a knitted, woven, or braided neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a multi-layer, concave neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an electromagnetic closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0127] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, framework, lattice, or mesh) which is inserted into the aneurysm sac in a first shape, then is expanded (e.g. self-expands) within the aneurysm sac into a spherical second shape, and then is compressed and/or folded into a hemispherical third shape with a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In an alternative example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) into a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a chemical closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0128] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck, wherein the neck bridge is made from a plurality of braided filaments; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck, wherein the neck bridge further comprises a radiopaque marker at its distal end; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0129] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge or stent expands in a radial-expansion plane which is parallel to the plane of the circumference of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self expands) to a bowl or cup shape within the proximal half of the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0130] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding into a bowl or cup shape with a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge has a proximal portion with a first porosity level and a distal portion with a second porosity level, and wherein the second porosity level is greater than the first porosity level; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0131] In an example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are transported through the catheter and inserted into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which is transported through the catheter in a radially-more-constrained first configuration, inserted into the aneurysm sac, and then expanded (e.g. self expanded) into a radially-less-constrained second bowl or cup shaped configuration, wherein the second configuration has a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0132] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils with a first cross-sectional shape which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac, wherein the opening has the first cross-sectional shape when it is open and a second cross-sectional shape when it is closed; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a pull-cord or pull-wire closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism closes the opening when a device user pulls on a cord or wire.
[0133] In one possible embodiment, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an elastic ring which closes the opening after the coils have been inserted into the aneurysm sac. In yet another embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a circular opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0134] In an example, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a opening in the neck bridge through which the coils are inserted into the aneurysm sac, wherein the opening is closer to the circumference of the neck bridge than to its central axis; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a plurality of openings in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) one or more closure mechanisms which close the plurality of openings after the coils have been inserted into the aneurysm sac.
[0135] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an off-center opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter extends and through which coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0136] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter extends and through which coils are inserted into the aneurysm sac; and (e) a closure mechanism which detaches the catheter from the neck bridge and closes the opening after coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter protrudes into the aneurysm sac.
[0137] In an example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a first diameter, wherein the aneurysm neck has a second diameter, wherein the aneurysm sac has a maximum third diameter in a plane which is parallel to the aneurysm neck, and wherein the first diameter is at least 125% of the second diameter and at least 80% of the third diameter; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0138] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a remotely-activated closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0139] In one possible embodiment, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) bowl or cup shape with a maximum first diameter, wherein the aneurysm neck has a maximum second diameter, wherein the aneurysm sac and a maximum third diameter, wherein the first diameter is between 125% and 300% of the size of the second diameter; and wherein the first diameter is between 75% and 100% of the size of the third diameter; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) with a radially-more-constrained first configuration and a radially-less-constrained second configuration; wherein the neck bridge is inserted into the aneurysm sac in its first configuration and then expanded into its second configuration; wherein the neck bridge has a bowl, cup, hemispherical, and/or paraboloidal shape in its second configuration; and wherein the neck bridge has a diameter which is greater than 90% of the maximum diameter of the aneurysm sac in its second configuration; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0140] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a resilient neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a toroidal neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0141] In an embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an arcuate neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a device to occlude an aneurysm can comprise: (a) a longitudinal lumen (e.g. a catheter); (b) one or more longitudinal embolic members (e.g. embolic coils) which are inserted into an aneurysm sac; (c) an expandable proximal member (e.g. a downwardly-convex neck bridge) which is expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck; (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac.
[0142] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a longitudinal lumen (e.g. a catheter); (b) one or more longitudinal embolic members (e.g. embolic coils) which are inserted into an aneurysm sac; (c) an expandable proximal member (e.g. an upward-opening-convex neck bridge) which is expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck; (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) to a disk shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the expandable proximal member through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0143] In an embodiment, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a drawstring, elastic ring, loop, and/or tie-off In an alternative example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a moveable plug or valve.
[0144] A bowl-of-spaghetti type aneurysm occlusion device can alternatively comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a clasp, clip, or snap. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a spring or elastic member with a first configuration which does not block (or otherwise close) the opening and a second configuration which blocks (or otherwise closes) the opening.
[0145] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism has a first configuration which does not block (or otherwise close) the opening and a second configuration which blocks (or otherwise closes) the opening, wherein the closure mechanism is changed from its first configuration to its second configuration by stopping the transmission of electrical current to it.
[0146] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member has a toroidal shape, bowl shape, convex lens shape, cup shape, paraboloid (of revolution) shape, inverted umbrella shape, and/or hemispherical shape after it has been expanded; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In an example, Arnold can see a bowl of spaghetti and say Vista La Pasta, Baby. In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is at least 20% larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which reduces the size of the opening after the coils have been inserted into the aneurysm sac.
[0147] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which reduces the size of the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism is remotely activated from a location outside the person's body by a device user. In another example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more longitudinal embolic members (e.g. embolic coils) which are inserted into an aneurysm sac; (c) an expandable upward-opening-convex neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac.
[0148] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an upward-facing-convex neck bridge self-expands within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge is made from a metal; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) and inflatable member (e.g. balloon); (d) a multi-layer, upward-facing-convex, neck bridge (e.g. stent, lattice, mesh, or framework) which is expanded by the inflatable member within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (e) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (f) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0149] In an embodiment, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the proximal half of the aneurysm sac into a paraboloidal shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through a central opening in the neck bridge; and (d) closing the opening in the neck bridge. In another example, a bowl-of-spaghetti type method for occluding an aneurysm can be embodied in: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the aneurysm sac of the into a hemispherical shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge.
[0150] In an example, a aneurysm occlusion method can comprise: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge into a bowl or cup shape with a diameter which is at least 20% wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. In an alternative example, a bowl-of-spaghetti type method for occluding an aneurysm can be embodied in: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge into a bowl or cup shape with a diameter which is between 90% and 100% of the maximum diameter of the aneurysm sac; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided multi-layer neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is at least 20% larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0151] In an example, an intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, an intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac; (c) an opening in the neck bridge; (d) liquid embolic material which is inserted into the aneurysm sac through the opening and then congeals within the aneurysm sac; and (e) a closure mechanism which closes the opening after the liquid embolic material has been inserted into the aneurysm sac. In another example, a aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided Nitinol neck bridge (e.g. stent, framework, lattice, or mesh) which is inserted into the aneurysm sac in a first shape, then is expanded (e.g. self-expands) within the aneurysm sac into a spherical second shape, and then is compressed and/or folded into a hemispherical third shape with a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0152] A bowl-of-spaghetti type intrasacular aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a braided, knitted, or woven neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a double-layer neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0153] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a multi-layer neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0154] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a multi-layer, convex neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an electromagnetic closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In yet another embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, framework, lattice, or mesh) which is inserted into the aneurysm sac in a first shape, then is expanded (e.g. self-expands) within the aneurysm sac into an ellipsoidal second shape, and then is compressed and/or folded into a bowl or cup third shape with a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0155] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a concave shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a prolate or oblate spheroidal shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0156] In one possible embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck, wherein the neck bridge further comprises one or more portions made with bismuth; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0157] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within the aneurysm sac at a location from which it contacts the aneurysm sac at the sac's maximum circumference; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0158] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self expands) to a bowl or cup shape within the most proximal one-third of the volume of the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac, wherein the coils have an average first cross-sectional area; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac, wherein the opening has a second cross-sectional area when open and a third cross-sectional area when closed, wherein the second cross-sectional area is at least 25% greater than the first cross-sectional area, and wherein the first cross-sectional area is at least 25% greater than the third cross-sectional area; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0159] A bowl-of-spaghetti type aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) within an aneurysm sac, expanding into a bowl or cup shape with a diameter which is larger than the diameter of the aneurysm neck, wherein the proximal half of the neck bridge has a first porosity level, wherein the distal half of the neck bridge has a second porosity level, and wherein the second porosity level is greater than the first porosity level; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which is inserted into the aneurysm sac, is expanded (e.g. self-expands) into a substantially spherical shape within the aneurysm sac, and then is collapsed into a double-layer, upward-opening, hemispherical shape which substantially covers the inside of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0160] In an embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are transported through the catheter and inserted into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which is transported through the catheter in a radially-more-constrained first configuration, inserted into the aneurysm sac, and then expanded (e.g. self expanded) from the first configuration to a radially-less-constrained second ellipsoidal configuration, wherein the second configuration has a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0161] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a spring which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) an electrical energy closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0162] A bowl-of-spaghetti type intrasacular aneurysm occlusion device can also comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a hexagonal opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more helical embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a opening in the neck bridge through which the coils are inserted into the aneurysm sac, wherein the opening is closer to the cross-sectional perimeter of the neck bridge than to the central axis of the neck bridge; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0163] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a quadrilateral opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in base of the neck bridge through which the coils are inserted into the aneurysm sac; (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac; and (f) a detachment mechanism which cuts or otherwise detaches segments of embolic coils.
[0164] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coil which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter extends and through which coils are inserted into the aneurysm sac; and (e) a closure mechanism which detaches a segment of embolic coil, detaches the catheter from the neck bridge, and closes the opening. In an alternative example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) an opening in the neck bridge through which the catheter extends and through which coils are inserted into the aneurysm sac; and (e) a closure mechanism which detaches the catheter from the opening and closes the opening.
[0165] In an example, an intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) bowl or cup shape with a maximum first diameter, wherein the aneurysm neck has a maximum second diameter, wherein the aneurysm sac and a maximum third diameter, wherein the first diameter is greater than the second diameter and less than the third diameter; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, an intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac; (c) an opening in the neck bridge; (d) a plurality of compressible embolic members (e.g. hydrogels or microsponges) which are inserted into the aneurysm sac through the opening; and (e) a closure mechanism which closes the opening after the liquid embolic material has been inserted into the aneurysm sac. In an example, an aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a first diameter, wherein the aneurysm neck has a second diameter, wherein the aneurysm sac has a maximum third diameter in a plane which is parallel to the aneurysm neck, and wherein the first diameter is at least 150% of the second diameter and at least 95% of the third diameter; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0166] In one possible embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac, expanding to a diameter which at least 90% of the maximum diameter of the aneurysm sac in a plane parallel to the aneurysm neck; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a remotely-activated closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) bowl or cup shape with a maximum first diameter, wherein the aneurysm neck has a maximum second diameter, wherein the aneurysm sac and a maximum third diameter, wherein the first diameter is between 110% and 200% of the size of the second diameter; and wherein the first diameter is between 85% and 100% of the size of the third diameter; (d) an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0167] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a Nitinol neck bridge (e.g. stent, framework, lattice, or mesh) which is inserted into the aneurysm sac in a first shape, then expanded (e.g. self-expands) within the aneurysm sac into a spherical second shape, and then compressed and/or folded into a hemispherical third shape with a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. Alternatively, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a shaped neck bridge (e.g. stent, lattice, mesh, or framework) which is inserted into the aneurysm sac, is expanded (e.g. self-expands) into a substantially ellipsoidal shape within the aneurysm sac, and then is collapsed into a double-layer, upward-opening, substantially paraboloidal shape which substantially covers the inside of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0168] In an embodiment, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) a toroidal neck bridge (e.g. stent, lattice, mesh, or framework) which is expanded within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0169] An aneurysm occlusion device can also comprise: (a) a longitudinal lumen (e.g. a catheter) which is configured into be inserted into a person's vasculature; (b) one or more longitudinal embolic members (e.g. embolic coils) which are configured to be delivered through the longitudinal lumen into an aneurysm sac; (c) an expandable proximal member (e.g. a bowl or cup shaped neck bridge) which is configured to be inserted and expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member spans the aneurysm neck after the expandable proximal member has been expanded; (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac. In another example, an intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) a neck bridge (e.g. stent, lattice, mesh, or framework) which expands (e.g. self-expands) to a bowl or cup shape within the aneurysm sac; (c) an opening in the neck bridge; (d) one or more string-of-pearls type longitudinal embolic members (e.g. microsponges connected by filaments) which are inserted into the aneurysm sac through the opening; and (e) a closure mechanism which closes the opening after the liquid embolic material has been inserted into the aneurysm sac. In another example, an aneurysm occlusion device can comprise: (a) a longitudinal lumen (e.g. a catheter); (b) one or more longitudinal embolic members (e.g. embolic coils) which are inserted into an aneurysm sac; (c) an expandable proximal member (e.g. an upwardly-convex neck bridge) which is expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck; (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac.
[0170] In an example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a longitudinal lumen (e.g. a catheter) which is configured into be inserted into a person's vasculature; (b) one or more longitudinal embolic members (e.g. embolic coils) which are configured to be delivered through the longitudinal lumen into an aneurysm sac; (c) an expandable proximal member (e.g. an upward-opening-convex neck bridge) which is configured to be inserted and expanded (e.g. self-expanded) within a proximal portion the aneurysm sac to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member spans the aneurysm neck; and (d) an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac. In an alternative example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member is a spherical stent which has been collapsed or folded into a hemispherical shape; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0171] In an embodiment, a device to occlude an aneurysm can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a pull cord or pull wire.
[0172] A bowl-of-spaghetti type intrasacular aneurysm occlusion device can alternatively comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism is an adhesive which is released into the opening. In another example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises application of electromagnetic energy to shape-memory material.
[0173] In an embodiment, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the closure mechanism further comprises a spring or elastic member with a first configuration which does not block (or otherwise close) the opening and a second configuration which blocks (or otherwise closes) the opening, wherein the spring or elastic member is changed from its first configuration to its second configuration by the transmission of electromagnetic energy. In another example, a device to occlude an aneurysm can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac, wherein the opening is held open by the transmission of electromagnetic energy and closes when the transmission of electromagnetic energy is stopped.
[0174] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the expandable proximal member has an annular shape, cylindrical shape doughnut shape, ring shape, tire shape, or wheel shape after it has been expanded; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0175] In an example, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is at least 50% larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which reduces the size of the opening after the coils have been inserted into the aneurysm sac. In another example, a bowl-of-spaghetti type aneurysm occlusion device can be embodied in: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an expandable proximal member (e.g. neck bridge) which expands (e.g. self-expands) within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a one-way valve which allows coils to be inserted through the opening into the aneurysm sac, but does not allow coils to escape out of the aneurysm sac.
[0176] A bowl-of-spaghetti type intrasacular aneurysm occlusion device can alternatively comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an inflatable toroidal neck bridge (e.g. stent, lattice, mesh, or framework) which is expanded within an aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. In yet another embodiment, a bowl-of-spaghetti type aneurysm occlusion device can comprise: (a) a catheter; (b) one or more embolic coils which are inserted through the catheter into an aneurysm sac; (c) an upward-facing-convex neck bridge self-expands within the aneurysm sac, expanding to a diameter which is larger than the diameter of the aneurysm neck, wherein the neck bridge is made from a polymer; (d) a (central) opening in the neck bridge through which the coils are inserted into the aneurysm sac; and (e) a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0177] In one possible embodiment, a bowl-of-spaghetti type method for occluding an aneurysm can be embodied in: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) allowing the neck bridge to self-expand into a spherical or ellipsoidal first shape; (c) axially contracting, compressing, and/or folding the neck bridge from the first shape into a double-layer hemispherical second shape; (d) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (e) closing the opening in the neck bridge. In another example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the aneurysm sac into a convex shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge.
[0178] In an example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a braided neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge in the aneurysm sac of the into a paraboloidal shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. In an alternative example, a bowl-of-spaghetti type method for occluding an aneurysm can comprise: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) expanding the neck bridge into a bowl or cup shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and (d) closing the opening in the neck bridge. In another example, a aneurysm occlusion method can be embodied in: (a) inserting a neck bridge (e.g. stent, lattice, mesh, or framework) into an aneurysm sac; (b) releasing the neck bridge to self expand into a bowl or cup shape with a diameter which is wider than the diameter of the aneurysm neck; (c) inserting embolic coils into the aneurysm sac through an opening in the neck bridge; and then (d) closing the opening in the neck bridge.
[0179] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: a longitudinal lumen which is configured into be inserted into a person's vasculature; one or more longitudinal embolic members which are configured to be delivered through the longitudinal lumen into an aneurysm sac in the person's vasculature; an expandable proximal member which is configured to be inserted into and expanded within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac.
[0180] In an example, a longitudinal lumen can be a catheter, longitudinal embolic members can be embolic coils, and an expandable proximal member can be a neck bridge. In an example, an expandable proximal member (e.g. neck bridge) can self expand within the aneurysm sac. In an example, an expandable proximal member (e.g. neck bridge) can expand into an upward-opening-convex shape. In an example, an expandable proximal member (e.g. neck bridge) can expand into a bowl or cup shape. In an example, an expandable proximal member (e.g. neck bridge) can be a braided or woven stent, lattice, mesh, and/or framework. In an example, an expandable proximal member (e.g. neck bridge) can be a 3D printed stent, lattice, mesh, and/or framework.
[0181] In an example, an expandable proximal member (e.g. neck bridge) can be a multi-layer neck bridge which is made by folding and/or compressing a generally spherical or ellipsoidal stent, lattice, mesh, or framework into a multi-layer bowl or cup shaped stent, lattice, mesh, or framework. In an example, an expandable proximal member (e.g. neck bridge) can be a multi-layer neck bridge which is made by folding and/or compressing a generally spherical or ellipsoidal stent, lattice, mesh, or framework within the aneurysm sac. In an example, an expandable proximal member (e.g. neck bridge) can be a multi-layer neck bridge which is made by folding, twisting, and/or inverting a generally tubular stent, lattice, mesh, or framework into a multi-layer bowl or cup shaped stent, lattice, mesh, or framework.
[0182] In an example, an expandable proximal member (e.g. neck bridge) can expand to a diameter which is at least 10% larger than the maximum diameter of the aneurysm neck. In an example, an expandable proximal member (e.g. neck bridge) can expand to a diameter which is at least 85% of the maximum diameter of the aneurysm sac. In an example, an expandable proximal member (e.g. neck bridge) can expand to a diameter which is at least 10% larger than the maximum diameter of the aneurysm neck and at least 85% of the maximum diameter of the aneurysm sac. In an example, a longitudinal lumen (e.g. catheter) can connect to and/or protrude into the opening in the expandable proximal member.
[0183] In an example, a closure mechanism can be remotely-activated by the application of electromagnetic energy. In an example, a closure mechanism can close the opening in the expandable proximal member and detach an embolic longitudinal member which has been inserted into the aneurysm sac. In an example, a closure mechanism can close the opening in the expandable proximal member, detach an embolic longitudinal member which has been inserted into the aneurysm sac, and detach the longitudinal lumen from the expandable proximal member so that the longitudinal lumen can be withdrawn from the person's vasculature.
[0184] In an example, a bowl-of-spaghetti type intrasacular aneurysm occlusion device can comprise: a catheter which is inserted into a person's vasculature; one or more embolic coils which are delivered through the catheter into an aneurysm sac; a neck bridge which expands into a bowl or cup shape within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck; an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac.
[0185] In an example, a bowl-of-spaghetti type method of occluding an aneurysm can comprise: inserting a catheter into a person's vasculature; inserting a neck bridge on or through the catheter into an aneurysm sac in the person's vasculature; expanding the neck bridge into a bowl or cup shape within the aneurysm sac, wherein the neck bridge is expanded to a diameter which is larger than the maximum diameter of the aneurysm neck; inserting one or more embolic coils into the aneurysm through the catheter and through an opening in the neck bridge; closing the opening in the neck bridge; and withdrawing the catheter from the person's vasculature.