IRIS COLOR CHANGING METHOD

Abstract

The invention is related to iris color changing method that ensures a color change in iris by shedding the layer that contain the cells with melanin pigments in the upper superficial part and stroma of the iris, colored part of the eye, through photo-disruptive effect.

Claims

1. (canceled)

2. (canceled)

3. A method for iris color changing, by diffusing the layer which has the cells that contains melanin pigments on upper surface of the iris, colored part of the eye, and its stroma, comprising: (1) applying 532 nanometer wavelength laser beam having a 1000 micrometer spot diameter to the pupillary iris region; (2) applying a 532 nanometer wavelength laser beam having a 1000 micrometer spot diameter to region of the iris between the pupillary region and the ciliary region of the iris; (3) applying a 1064 nanometer wavelength laser beam having 8 micrometer spot diameters to a region of the collarette of the iris wherein there are blood vessel anastomosis, while the direction of the focus of the eye moves either clockwise or counterclockwise; and (4) applying a 1064 nanometer wavelength laser beam having 8 micrometer spot diameters to a ciliary region of the iris, while the direction of the focus of the eye moves either clockwise, or counterclockwise.

4. The method of claim 3, further comprising: (5) applying 532 nanometer wavelength laser beam having a 2000 micrometer diameter spot size to a ciliary region of the iris.

5. The method of claim 3, further comprising: (6) irrigating the iris pigments in the front, that is anterior, chamber, by with a solution comprising BSS Plus or Isolyte solution.

6. The method of claim 4, further comprising: after said irrigating step (6), (7) applying a 532 nanometer wavelength laser beam having 1000 micrometer diameter spot size to a pupilary region of the iris; and after said irrigating step (6), (8) applying a 532 nanometer wavelength laser beam having 2000 micrometer diameter spot size to a ciliary region of the iris.

7. The method of claim 3, further comprising: after steps numbered (1) to (4), (9) determining whether there are pigmented areas in the superficial layer and/or stroma of iris.

8. The method of claim 7 wherein, if further comprising: after step (9), repeating at least one of steps (1) to (4).

9. The method of claim 1, further comprising: prior to steps (1), (2), (3), and (4), applying to the eye Pilokarpin HCl to constrict the pupil of the eye; and prior to steps (1), (2), (3), and (4), applying to the eye Proparakain HCl to anesthetize the eye.

10. The method of claim 1, further comprising: prior to step (1), interposing a YAG laser capsulotomy lens between the eye and the source of the laser beam, so that the 532 nanometer wavelength laser beam having a 1000 micrometer spot diameter of step (1) pass through the YAG laser capsulotomy lens before reaching the eye.

11. The method of claim 1, further comprising: prior to step (2), interposing a YAG laser iridotomy lens between the eye and the source of the laser beam, so that the 532 nanometer wavelength laser beam having a 1000 micrometer spot diameter of step (2) pass through the YAG laser iridotomy lens before reaching the eye.

12. The method of claim 1, further comprising: prior to step (3), interposing a YAG laser iridotomy lens between the eye and the source of the laser beam, so that 1064 nanometer wavelength laser beam having 8 micrometer spot diameters of step (3) pass through the YAG laser iridotomy lens before reaching the eye.

13. The method of claim 1, further comprising: prior to step (4), interposing a YAG laser iridotomy lens between the eye and the source of the laser beam, so that the 1064 nanometer wavelength laser beam having 8 micrometer spot diameters of step (4) pass through the YAG laser iridotomy lens before reaching the eye.

14. The procedure defined in 5, repeating the applying steps of claim 3 and then repeating the irrigating step of claim 5.

15. The procedure of claim 3, wherein during the step (3), the laser beam is vertical to the iris.

16. The method of claim 1, further comprising: prior to step (3), interposing a YAG laser iridotomy lens between the eye and the source of the laser beam, so that 1064 nanometer wavelength laser beam having 8 micrometer spot diameters of step (3) pass through the YAG laser iridotomy or capsulotomy lens before reaching the eye.

17. The method of claim 4, further comprising: after said irrigating step (6), (7) applying a 532 nanometer wavelength laser beam having 50-1000 micrometer diameter spot size to a pupilary region of the iris; and after said irrigating step (6), (8) applying a 532 nanometer wavelength laser beam having 2000 micrometer diameter spot size to a ciliary region of the iris.

18. The method of claim 1, further comprising: prior to step (1), interposing a YAG laser capsulotomy lens between the eye and the source of the laser beam, so that the 532 nanometer wavelength laser beam having a 1000 micrometer spot diameter of step (1) pass through the YAG laser capsulotomy lens before reaching the eye.

19. The method of claim 1, further comprising: prior to step (2), interposing a YAG laser iridotomy lens between the eye and the source of the laser beam, so that the 532 nanometer wavelength laser beam having a 50-1000 micrometer spot diameter of step (2) pass through the YAG laser iridotomy lens before reaching the eye.

Description

EXPLANATION OF THE INVENTION

[0023] Iris color changing method developed with this invention was not developed for diagnosis or treatment purposes. Iris color changing method developed in this invention is for cosmetic and aesthetic purposes only. That is to say, a person with brown eyes or other colored eyes is not the cause of any disease. This method is for changing the color of eyes for aesthetic purposes only. The invention is a method for changing the color of the iris, prior to laser operation, pre-laser preparation (preoperative), laser application and post-laser (postoperative) to Irrigation Aspiration (I/A) operation of the eye under sterile conditions when required;

[0024] aTwice 2% Pilokarpin HCl (Pilosed) with 5 minute intervals 15 minutes prior to laser application to create myosis effect and three times Proparakain HCl 0.5% (Alcaine) with 5 minute intervals 10 minutes prior for anesthesia are dropped. This way myosis and anesthesia is ensured. (Because iris evens out when Pilokarpin is dropped, it should be noted that a small decrease would occur in normal thickness).

[0025] bWhen laser is applied to pupillary iris, collaret and ciliary iris, YAG laser capsulotomy lens shall be put on and when you want to apply laser to peripheral ciliary iris area the 1-2 mm part of the peripheral of iris starting from limbus or by observing the iris in more detail, it should be applied by putting on YAG laser iridotomy lens,

[0026] cAvoiding laser beam in the pupil area,

[0027] dApplying 532 nanometer wavelength 1000 micrometer spot diameter laser application to Pupillary iris (Pupillary area of iris),

[0028] eApplying laser beam with 532 nanometer wavelength and 1000 micrometer spot diameter to Collarette (Swollen circle between pupillary and ciliary areas of the iris. Because in this area blood vessels are concentrated and anastomosed, in order to decrease bleeding) area,

[0029] fIf adequate pigment shedding and pupillary iris color lightening can't be achieved with 532 nanometer wavelength in Pupillary Iris and Collarette area; approach these areas carefully, don't approach the pupilla, focus on the anterior facet of iris, don't focus on the posterior facet pigment epithelium, penetration depth in which the laser beam effects shouldn't exceed 200-300 micrometers, leaving iris stromal cavity on the iris posterior facet that the laser doesn't effect to avoid break down of pupillary function at 200 micrometers, very carefully apply to the collarette area where blood vessel anastomosis are placed, laser beam shall be vertical to the iris and applied at 1064 nanometer wavelength at 8 micrometer spot diameter by decreasing the power of the laser and whilst directing the eye upwards, right, downwards and left (according to whichever clock dial it shall be done, the opposite clock dial shall be looked at),

[0030] gCiliary iris (Ciliary area of the iris) laser beam shall be vertical to the iris and applied at 1064 nanometer wavelength at 1064 wavelength, 8 micrometer spot diameter and penetration depth below 300 micrometers, and whilst directing the eye upwards, right, downwards and left (according to whichever clock dial it shall be done, the opposite clock dial shall be looked at) to break the superficial layer faster

[0031] hWhen the number of pigments shedding from the superficial layer of ciliary iris to the front chamber is less than 25 large particles or 100 small cells in an area of 1 mm.sup.3, laser beam shall be applied to the deep layers of Ciliary Iris area at 532 nanometer wavelength, 2000 micrometer spot diameter in the same session,

[0032] iWhen the number of pigments shedding from the superficial layer of ciliary iris to the front chamber is more than 25 large particles or 100 small cells, don't apply 2000 micrometer spot diameter laser beam at 532 nanometer wavelength to the deep layers of Ciliary Iris area in the same session, pause the laser operation and irrigate the iris pigments in the front chamber through Irrigation Aspiration (I/A) under sterile conditions with BSS Plus or Isolyte solution (BSS Plus contains: 4.6 mg Glutation disulphide Solution, 2.19 mg Sodium bicarbonate Solution, 0.433 mg Sodium phosphate Solution, 7.44 mg Sodium chloride Solution, 0.395 mg Potassium chloride Solution, 3.85 mg Calcium chloride dihydrate Solution, 23.0 mg Dextrose anhidrosis Solution, 5.0 mg Magnesium chloride hexahydrate Solution or Isolyte contains: Sodium acetate 3H.sub.20 0.64%, Sodium chloride 0.5%, Sodium citrate 0.075%, Potassium chloride 0.075%, Calcium chloride dihydrate 0.035%, Magnesium chloride 6H.sub.20 0.031%) (In this way glaucoma risk is decreased and it's ensured for the laser to achieve the tissue with more effectiveness in the next session).

[0033] jApplication of respectively 1000 and 2000 micrometers spot diameter laser beam with 532 nanometer wavelength in Pupillary and Ciliary area after FA, consists of the steps above and takes approximately five to ten minutes per eye.

[0034] After steps (a, b, c, d, e, f, g, h, i and j) above, in a biomicroscopic examination on the eye applied with steps (a, b, c, d, e, f, g, h, i and j), if there are pigmented areas in the superficial layer and/or stroma of iris, steps required out of a, b, c, d, e, f, g, h, i and j are re-applied as necessary, the session is repeated until the pigmented areas disappear.