Fluid handling containers, systems, and related methods
10597211 ยท 2020-03-24
Assignee
Inventors
Cpc classification
B65D77/065
PERFORMING OPERATIONS; TRANSPORTING
B01F33/453
PERFORMING OPERATIONS; TRANSPORTING
B01F33/813
PERFORMING OPERATIONS; TRANSPORTING
B67D7/08
PERFORMING OPERATIONS; TRANSPORTING
B01F35/513
PERFORMING OPERATIONS; TRANSPORTING
International classification
B65D77/06
PERFORMING OPERATIONS; TRANSPORTING
B67D7/08
PERFORMING OPERATIONS; TRANSPORTING
Abstract
An apparatus (10) receives an at least partially flexible vessel (14) adapted for receiving a fluid. The apparatus (10) may include an overpack (12) and a partition (16) removably positioned in an interior of the overpack (12). The partition (16) may extend generally transverse to a sidewall (12b) and generally aligned with a floor (12c) of the overpack (12) to form a compartment for receiving the vessel (14). The partition (16) may also form part of a carrier (17) for the vessel (14). A filling station for filling containers (10) is also disclosed, as are related methods.
Claims
1. An apparatus for receiving an at least partially flexible vessel adapted for receiving a fluid, comprising: an overpack including a base having a floor and an upstanding sidewall forming an interior for receiving the vessel; and a partition removably positioned in the interior of the overpack, the partition extending generally transverse to the sidewall and generally aligned with the floor to form a compartment in the interior of the overpack for receiving the vessel; wherein the base of the overpack includes a door for providing access to an exterior compartment of the base.
2. The apparatus of claim 1, wherein the overpack includes at least one hanger for hanging the overpack.
3. The apparatus of claim 2, wherein the base includes the at least one hanger.
4. The apparatus of claim 1, wherein the overpack includes an upper wall adapted for receiving a conduit for connecting with the vessel in the overpack.
5. The apparatus of claim 4, wherein the partition is adapted for receiving the conduit.
6. The apparatus of claim 1, wherein the partition includes an apex formed by a pair of sloped walls adapted for causing fluid to drain from the vessel.
7. The apparatus of claim 1, further including a coupler adapted for forming a non-contact coupling with a component in the vessel.
8. The apparatus of claim 7, wherein the component comprises a magnetic agitator, and the coupler comprises a material for forming a magnetic coupling with the magnetic agitator.
9. The apparatus of claim 1, further including a retainer for removably retaining the partition within the interior compartment of the overpack.
10. The apparatus of claim 1, wherein the overpack further includes at least one receiver adapted for receiving a lifting device.
11. The apparatus of claim 1, wherein the overpack comprises a handle, the handle comprising at least one opening formed in at least one sidewall of the overpack, the opening adapted for being grasped by a hand of a user.
12. The apparatus of claim 1, further including a tubing positioned in a space between an upper surface of the partition and a lower surface of an upper wall of the overpack.
13. The apparatus of claim 1, further including a carrier adapted for receiving the vessel and for nesting in the interior of the overpack.
14. The apparatus of claim 1, further including a support for supporting the partition in at least an inverted condition of the overpack.
15. An apparatus, comprising: an at least partially flexible vessel adapted for receiving a fluid, the vessel including an agitator; an overpack including a base having a floor and an upstanding sidewall forming an interior for receiving the vessel; and a partition removably positioned in the interior of the overpack, the partition extending generally transverse to the sidewall and generally aligned with the floor to form a compartment in the interior of the overpack for receiving the vessel.
16. The apparatus of claim 15, wherein the base of the overpack includes a door for providing access to an exterior compartment of the base separate from the interior of the vessel.
17. An apparatus, comprising: at least partially flexible vessel adapted for receiving a fluid, the vessel including an upper portion having a conduit for communicating fluid to or from an interior compartment of the at least partially flexible vessel, and a lower portion; an overpack including a base having a floor for supporting the lower portion of the at least partially flexible vessel and an upstanding sidewall forming an interior; and a partition removably positioned in the interior of the overpack, the partition extending generally transverse to the sidewall and generally aligned with the floor, the partition forming a first compartment in the interior of the overpack for receiving the at least partially flexible vessel and a second compartment for receiving the conduit connected to the upper portion of the at least partially flexible vessel; and a hanger associated with the base of the overpack for hanging the vessel in an inverted condition for draining the fluid from the interior compartment of the at least partially flexible vessel through the conduit.
18. The apparatus of claim 17, wherein the base of the overpack includes a door for providing access to an exterior compartment of the base below the floor.
19. The apparatus of claim 17, wherein the hanger comprises a pair of hangers, each of the pair of hangers including an opening for aligning for receiving a support for supporting the overpack in an inverted condition.
20. The apparatus of claim 19, wherein each hanger comprises a flap connected to the overpack.
Description
BRIEF DESCRIPTION OF THE DRAWING FIGURES
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
DETAILED DESCRIPTION
(14) Reference is now made to
(15) A divider or partition 16 is located in the interior of the overpack 12 to form a compartment for receiving the vessel or bag 14, and is generally oriented in a plane parallel to the upper and lower walls 12a, 12c and thus transverse to the sidewall 12b. In one aspect of the disclosure, the partition 16 is removable from the interior compartment of the overpack 12, yet capable of being retained in a particular position (such as adjacent to the upper portion of the bag 14) when the overpack is inverted. This retention may be accomplished by way of an attachment to the overpack 12, such as by using mechanical fasteners R (e.g., clips, screws, bolts, or the like) for connecting to the inner surface of the sidewall(s) 12b. Alternatively, fasteners in the form of adhesives (including tape), hook-and-loop fasteners, magnets, or the like could be used, alone or in combination with other fasteners. Still another alternative, as described in more detail below, is to provide vertically extending supports (such as spacers, blocks, legs, posts, dowels, etc., whether integral or otherwise) for supporting the partition 16 when the overpack 12 is inverted (which supports would engage the lower wall, which it should be appreciated is the upper wall 12a in the non-inverted condition).
(16) Prior to being fixed in place, the partition 16 in the illustrated embodiment may be moved to a desired position along the interior of the overpack 12. This ability for relative movement advantageously allows the container 10 to be used in connection with a variety of shapes and sizes of bags, simply by making the necessary height adjustment. Further, this may allow for reuse of the overpack 12 with a replacement bag (possibly of a different size or shape), once a fluid processing operation is completed.
(17) As shown in
(18) The partition 16 may be arranged to expose any ports 14a associated with the bag 14. This may be done by providing an opening 16a in the partition 16 sized and shaped to accommodate any port fitment. Specifically, the opening 16a may be arranged to allow the fitment base to register therein. This registration may provide an assurance as to the location of the ports 14a, which may be desirable for reasons that will be understood upon reviewing the following disclosure.
(19) As mentioned previously,
(20) The flap or flaps, when present, should allow for the passage of the fluid, such as through the conduit 18, even when closed. This may be accomplished by providing an opening O for this purpose (which may be in any one flap, or between multiple flaps). Alternatively, this opening may be provided in the sidewall 12b or lower wall 12c of the overpack 12, if necessary or desired for a particular operation. Likewise, there could be one or more openings in more than one of these walls 12a, 12b, 12c, as necessary or desired.
(21) Another aspect of the disclosure relates to the ability to recover the fluid from the bag 14 by inverting it, as shown in
(22) To facilitate use in an inverted condition, the overpack 12 may be provided with one or more hangers. For example, as shown in
(23) In this condition, the aligned openings 20a forming the hangers may readily receive a support structure for supporting the entire container 10 in the inverted condition. For instance, the structure for positioning in the openings 20a may comprise the bifurcated components, such as forks F, of a lifting device D. This lifting device D may be static, as shown in
(24) In some instances, the bag 14 may include a component used during the fluid processing operation, such as for example a magnetic agitator 22 for agitating the fluid as the result of a non-contact coupling with an external motive device (which avoids the need to dynamic seals and shafts and thus helps to maintain the sterile condition of the interior compartment of the bag, when such is desired for a particular processing regimen). Such a magnetic agitator 22 may be retained against lateral movement by a post 22a (as described in detail in U.S. Pat. No. 7,481,572, the disclosure of which is incorporated herein by reference), but may be allowed to move along the post in the vertical direction (note arrow V) in order to accommodate the formation of a non-contact (e.g., magnetic) coupling with an external motive device (not shown).
(25) To prevent such movement prior to use or after inversion, and thus reduce the risk of potential perforation should the walls of the bag come into contact with any part of the agitator 22 (such as the blades typically included), a retainer in the form of an external coupler 24 may be provided for forming a non-contact (again, possibly magnetic) coupling with the agitator 22. In one embodiment, this coupler 24 may be a thin, disc-shaped structure formed of a magnetic material, and may include a central opening for receiving any locator projection (not shown) for ensuring proper alignment.
(26) As shown in
(27) It should also be appreciated that the inclusion of the mixer in the vessel (bag 14) allows for the single container 10 to be used for filling, processing, and then dispensing. Indeed, in cases where the fluid is not homogenized during filling, or when time has passed since filling such that the fluid has perhaps separated or settling has occurred, the mixer may advantageously be used for agitation and re-suspension prior to dispensing the fluid.
(28) The container 10 may also be adapted to allow for easy manual lifting in either the inverted or non-inverted condition. Turning to
(29) Turning back to
(30) With continued reference to
(31) Turning to
(32) With further reference to
(33) Each branch line 106 may connect with the free end of the conduit 18 of each container 10 for which filling is desired (possibly with a suitable relief valve to allow air to escape the vessel during filling), or may be connected directly to the port 14 of the flexible vessel, as shown. Each branch line 106 is also associated with a valve, such as a pinch valve 108 (e.g., ACRO Model 284 or Model 958), for controlling the fluid flow. Accordingly, by opening the valves and pumping the fluid through the delivery line 104, it flows through the branch lines 106 and ultimately to the containers 10. Once filled to the desired level, the delivery may be halted by closing the valve 108. The filled container 10 may be removed from the system 100 for later use, such as by being palletized as previously described and shown in
(34) In many instances, the filling of the vessels of each container 10 may not proceed at the same level due to various factors, such as flow rates, pressure, folds, and the like. Rather than having an operator visually monitor the filling operation or use level sensors, which may lead to inconsistent results in the event the bag 14 becomes folded in the overpack 12 prior to or during filling, the filling operation may be automated by associating each valve with a control system that controls the valve in order to regulate the fluid flow. As an example, each container 10 may be associated with a scale 110 for weighing the container 10 and fluid F. Using feedback, such as an output signal from a controller (see
(35) Once filling is complete, the bag 14 or vessel of each container 14 may be sealed. This may be done using an aseptic tube sealing system for sealing the conduit 18, such as a QUICKSEAL device. Alternatively, a fitting may be provided on the conduit 18, including possibly one incorporating a sterile filter.
(36) Still referencing
(37) An upstream pump, such as a peristaltic pump 114, may be used to control the flow to this bag 112, such as by opening to allow gas to pass and then closing before fluid is introduced to the delivery line 104. An associated valve 116 (e.g., a PENDOTECH throttling pinch valve) may be used to close delivery line 104 and thus prevent any flow from returning to the source, such as tank 102.
(38) Likewise, once filling is complete, fluid remaining in the line 104 must be purged. A second reservoir, such as a bag 118, may be provided adjacent to the end of the line 104, and may also be associated with a valve, such as a pinch valve 120. This valve 120 is normally closed during the initial purge and filling operation, but then opened when the valves 108 and 116 are closed. The peristaltic pump 114 may then be used to force the remaining fluid to flow into the bag 118 serving as the second reservoir.
(39) With reference again to
(40) A second embodiment of the container 10 is also disclosed, with reference to
(41)
(42) As mentioned above, it should be appreciated that the extensions 17d (whether in the form shown or otherwise, such as for example Styrofoam blocks adhered in place) may be used in connection with other embodiments, such as the embodiment of
(43) An optional step of assembly may be to retain the port 14a of the vessel or bag 14 relative to the carrier 17. As shown in
(44) Turning now to
(45) As mentioned above, the bag 14 is typically formed of one or more layers of thin polymer film, such as polypropylene or polyethelyene. As contrasted with this flexible film, the overpack 12 may be constructed of considerably more rigid materials, such as cardboard, paperboard, plastic, and combinations thereof (with a preference for lightweight materials that can withstand multiple uses and ultimately be recycled). The materials of the overpack 12 may also be reinforced or corrugated for added strength and crush resistance. However, it is also possible to form the overpack 12 of metal in order to provide a more robust container 10, but with corresponding limitations in terms of cost and weight.
(46)
(47) As also shown in
(48) Turning back to
(49) The foregoing descriptions of several embodiments made according to the disclosure of certain inventive principles herein are presented for purposes of illustration and description. The embodiments described are not intended to be exhaustive or to limit the invention to the precise form disclosed and, in fact, any combination of the components of the disclosed embodiments is contemplated. The term flexible as used herein in the context of the vessel refers to a structure of the vessel that, in the absence of auxiliary support, may conform to the shape of the fluid contained in the vessel, as contrasted with a rigid structure, which retains a pre-determined shape when the fluid is present in the vessel. Modifications or variations are possible in light of the above teachings. For instance, measuring of the fluid into the vessels may be achieved using flow meters or a diaphragm pump associated with the branch lines. The wall of the carrier 17 serving as the partition 16 may also be made adjustable such that the carrier may be adapted to accommodate different sizes of bags. The embodiments described were chosen to provide the best illustration of the principles of the invention and its practical application to thereby enable one of ordinary skill in the art to utilize the invention in various embodiments and with various modifications as are suited to the particular use contemplated. All such modifications and variations are within the scope of the invention when interpreted in accordance with the breadth to which it is fairly, legally, and equitably entitled.