Health functional food for reducing and preventing capillary hemorrhage

20200061009 ยท 2020-02-27

    Inventors

    Cpc classification

    International classification

    Abstract

    Provided is a health functional food that contains a variety of active ingredients and can improve blood flow as well as reduce or prevent capillary hemorrhage, which can help to maintain health.

    Claims

    1. A health functional food for reducing or preventing capillary hemorrhage, comprising: 40 to 50 parts by weight of L-glutamine; 40 to 50 parts by weight of L-lysine hydrochloride; 5 to 15 parts by weight of L-arginine; 10 to 20 parts by weight of N-acetyl glucosamine; 10 to 20 parts by weight of a safflower seed extract powder; 0.1 to 5 parts by weight of a cinnamon extract powder; 150 to 200 parts by weight of a white poria cocos Wolf extract powder; 1 to 3 parts by weight of copper gluconate; 1 to 3 parts by weight of glycerin fatty acid ester; 2 to 4 parts by weight of nicotinamide; 4 to 6 parts by weight of a pumpkin extract powder; 50 to 70 parts by weight of a Paeonia japonica extract powder; 1 to 2 parts by weight of vitamin A; 0.1 to 0.5 parts by weight of vitamin B12; 15 to 25 parts by weight of vitamin B1; 0.2 to 0.6 parts by weight of vitamin B6; 100 to 200 parts by weight of vitamin C; 5 to 15 parts by weight of vitamin E; 10 to 20 parts by weight of magnesium oxide; 15 to 25 parts by weight of a mulberry leaf extract powder; 10 to 15 parts by weight of magnesium stearate; 0.1 to 0.3 parts by weight of folic acid; 3 to 7 parts by weight of octacosanol; 100 to 150 parts by weight of an Angelica gigas extract powder; 5 to 10 parts by weight of a Cordyceps sinensis extract powder; 20 to 30 parts by weight of inositol; 10 to 15 parts by weight of silicon dioxide; 5 to 10 parts by weight of titanium dioxide; 1 to 3 parts by weight of Gardenia yellow color; 5 to 15 parts by weight of carboxymethyl cellulose calcium; 5 to 10 parts by weight of quercetin; 5 to 10 parts by weight of a coenzyme; 50 to 80 parts by weight of taurine; 50 to 80 parts by weight of a kudzu extract powder; 10 to 30 parts by weight of a pine bark extract powder; 0.1 to 1.5 parts by weight of ferrous fumarate; 15 to 25 parts by weight of hydroxypropyl methylcellulose (HPMC); and to 25 parts by weight of hydroxypropyl cellulose (HPC).

    Description

    BRIEF DESCRIPTION OF THE DRAWINGS

    [0016] The above and other objects, features and other advantages of the present invention will be more clearly understood from the following detailed description taken in conjunction with the accompanying drawings, in which:

    [0017] FIGS. 1A to 1E are images showing changes in capillaries in test subjects with capillary hemorrhage after administration of two 1,000 mg tablets obtained from food prepared in accordance with Example 1; and

    [0018] FIGS. 2A to 2C are images showing changes in capillaries in test subjects with capillary hemorrhage after administration of two 1,000 mg tablets obtained from food prepared in accordance with Example 2.

    DETAILED DESCRIPTION OF THE INVENTION

    [0019] Hereinafter, preferred examples of the present invention will be described in more detail. However, these examples are provided only for illustration of the present invention and should not construed as limiting the scope of the present invention.

    Example 1

    [0020] In Example 1, a health functional food was prepared in accordance with the following ingredients and compositions.

    [0021] L-glutamine 45.5 mg, L-lysine hydrochloride 45.5 mg, L-arginine (Korea, Daesang Corp.) 10 mg, N-acetyl glucosamine 14 mg, safflower seed extract powder 14 mg, cinnamon extract powder mg, white poria cocos Wolf extract powder 170 mg, copper gluconate 1.917 mg, glycerin fatty acid ester 2.1 mg, nicotinamide (China) 3.2 mg, pumpkin extract powder 5 mg, Paeonia japonica extract powder 60 mg, vitamin A mixture powder (Switzerland) 1.504 mg, vitamin B12 (100%) 0.333 mg, vitamin B1 nitrate (Germany) 20.5 mg, vitamin B6 hydrochloride (Germany) 0.4 mg, vitamin C (United Kingdom) 150 mg, vitamin E mixture powder (DSM) 11.2 mg, magnesium oxide 17 mg, mulberry (leaf) extract powder 21.8 mg, magnesium stearate (Singapore) 12.6 mg, folic acid (Switzerland) 0.166 mg, octacosanol (1%, Korea) 5 mg, Angelica gigas extract powder 110 mg, Cordyceps sinensis extract powder 8.3 mg, inositol 24.5 mg, silicon dioxide 12.6 mg, titanium dioxide 7 mg, Gardenia yellow color (600 PD, Dube Corp. Inc.) 2 mg, carboxymethyl cellulose calcium 10 mg, quercetin 7 mg, coenzyme Q10 (Jupiter International Co., Ltd.) 8.4 mg, taurine 69.5 mg, kudzu (root) extract powder 69.5 mg, pine bark extract powder 16.4 mg, ferrous fumarate 1.08 mg, hydroxypropyl methylcellulose (HPMC) 21 mg, and hydroxypropyl cellulose (HPC) 20 mg.

    [0022] FIGS. 1A to 1E are images showing changes in capillaries in test subjects with capillary hemorrhage after administration of two 1,000 mg tablets obtained from food prepared in accordance with Example 1.

    TABLE-US-00001 TABLE 1 Administration Comparison in images between Name Gender period before and after administration Doo*Hee Male 35 days As can be seen from FIG. 1A, (2018.01.29. to hemorrhage disappeared in the 2018.03.05.) central upper part after administration of food of Example 1 Park*Soon Female 27 days As can be seen from FIG. 1B, (2017.12.01. to hemorrhage disappeared in the 2017.12.28.) right upper part after administration of food of Example 1 Yoon*Ha Male 30 days As can be seen from FIG. 1C, (2018.04.24. to hemorrhage like small spots 018.05.24.) disappeared and capillary wall became bright Lee*Hwa Female 4 months As can be seen from FIG. 1D, (2018.02.05. to hemorrhage disappeared in the left 2018.06.07.) upper part after administration of food of Example 1 Joo*Ok Female 27 days As can be seen from FIG. 1E, (2017.12.01. to overall scattered small hemorrhage 2017.12.28.) almost disappeared after f administration of ood of Example 1

    [0023] As can be seen from FIGS. 1A to 1E and Table 1, when the health functional food of Example 1 according to the present invention is administrated, capillary hemorrhage can be reduced.

    Example 2

    [0024] In Example 2, a health functional food was prepared in accordance with the following ingredients and compositions.

    [0025] L-glutamine 45.5 mg, L-lysine hydrochloride 45.5 mg, L-arginine (Korea, Daesang Corp.) 10 mg, N-acetyl glucosamine 14 mg, safflower seed extract powder 14 mg, cinnamon extract powder 1 mg, white poria cocos Wolf extract powder 110 mg, fermented Hosta longipes leaf powder 60 mg, copper gluconate 1.917 mg, glycerin fatty acid ester 2.1 mg, nicotinamide (China) 3.2 mg, pumpkin extract powder 5 mg, Paeonia japonica extract powder 60 mg, vitamin A mixture powder (Switzerland) 1.504 mg, vitamin B12 (100%) 0.333 mg, vitamin B1 nitrate (Germany) 20.5 mg, vitamin B6 hydrochloride (Germany) 0.4 mg, vitamin C (United Kingdom) 135 mg, vitamin E mixture powder (DSM) 11.2 mg, magnesium oxide 17 mg, mulberry (leaf) extract powder 21.8 mg, fermented Scabiosa mansenensis powder 15 mg, magnesium stearate (Singapore) 12.6 mg, folic acid (Switzerland) 0.166 mg, octacosanol (1%, Korea) 5 mg, Angelica gigas extract powder 110 mg, Cordyceps sinensis extract powder 8.3 mg, inositol 24.5 mg, silicon dioxide 12.6 mg, titanium dioxide 7 mg, Gardenia yellow color (600PD, Dube Corp. Inc.) 2 mg, carboxymethyl cellulose calcium 10 mg, quercetin 7 mg, coenzyme Q10 (Jupiter International Co., Ltd.) 8.4 mg, taurine 69.5 mg, kudzu (root) extract powder 69.5 mg, pine bark extract powder 16.4 mg, ferrous fumarate 1.08 mg, hydroxypropyl methylcellulose (HPMC) 21 mg, and hydroxypropyl cellulose (HPC) 20 mg.

    [0026] Here, the fermented powder was obtained by crushing dried Hosta longipes leaves (or Scabiosa mansenensis), immersing the same in distilled water, seeding a Bacillus subtilis starter, fermenting at 41 C. for 5 days to obtain a fermented product, and lyophilizing and grinding the fermented product.

    [0027] FIGS. 2A to 2C are images showing changes in capillaries in test subjects with capillary hemorrhage after administration of two 1,000 mg tablets obtained from food prepared in accordance with Example 2.

    TABLE-US-00002 TABLE 2 Administration Comparison in images between Name Gender period before and after administration Kim*Sook Female 3 weeks As can be seen from FIG. 2A, (2018.02.02. to hemorrhage disappeared in the 2018.02.23.) central upper part and capillary became entirely bright after administration of food of Example 2 An*Ja Female 3 weeks As can be seen from FIG. 2B, (2018.02.02. to great hemorrhage disappeared in 2018.02.23.) the right upper edge after administration of food of Example 2 Kim*Ja Female 17 days As can be seen from FIG. 2C, (2018.02.05. to great hemorrhage completely 2018.02.22.) disappeared in the central part after administration of food of Example 2

    [0028] As can be seen from FIGS. 2A to 2E and Table 2, when the health functional food of Example 2 according to the present invention is administrated, capillary hemorrhage can be reduced. In addition, Example 2 is different from Example 1 in that Example 2 exhibits an effect of reducing hemorrhage even if the food is administered for a relatively short period. More specifically, Example 1 exhibits an effect of reducing hemorrhage after administration for a period of 30 days or more on average, Example 2 exhibits an effect of reducing hemorrhage after administration for a period of about 20 days on average.

    [0029] The health functional food for reducing or preventing capillary hemorrhage according to the present invention cures wounds in capillaries, thereby reducing or preventing hemorrhage, and in the long term, maximizing strength and elasticity of blood vessels, and preventing and treating blood circulation disorders.

    [0030] As is apparent from the above description, the present invention provides a health functional food that contains a variety of active ingredients and can improve blood flow as well as reduce or prevent capillary hemorrhage, which is advantageously beneficial for maintaining health.

    [0031] The effects of the present invention are not limited to those mentioned above and other effects will be clearly understood to those skilled in the art from the aforementioned description.

    [0032] Although the preferred embodiments of the present invention have been disclosed for illustrative purposes, those skilled in the art will appreciate that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims.