HYDROGEL SURGICAL DRESSING PRODUCT HAVING A MULTI-DIMENSIONAL FLEXIBLE HYDROPHILIC STRUCTURE-LINKAGE COMPOSITE

20200046876 ยท 2020-02-13

    Inventors

    Cpc classification

    International classification

    Abstract

    This invention provides a hydrogel surgical dressing product having a designed multi-dimensional flexible hydrophilic structure-linkage composite, comprising: a hydrogel cushion layer, and a multiple of hydrophilic microsphere, wherein said multi-dimensional flexible hydrophilic structure-linkage composite comprising a hydrophilic multi-dimensional flexible structure-linkage membrane, and a multiple of structure-linkage holes positioned into said hydrophilic multi-dimensional flexible structure-linkage membrane, and the sizes of structure-linkage holes changed with the degree of compelling force, resulting in a multi-dimensional flexible structure-linkage relationship and a consolidating structure.

    Claims

    1. A hydrogel surgical dressing product, comprising: a hydrogel cushion layer; and a multi-dimensional flexible hydrophilic structure-linkage composite, wherein said multi-dimensional flexible hydrophilic structure-linkage composite comprising a hydrophilic multi-dimensional flexible structure-linkage membrane, and a multiple of structure-linkage holes positioned into said hydrophilic multi-dimensional flexible structure-linkage membrane, and the sizes of structure-linkage holes change with the degree of compelling force, resulting in a multi-dimensional flexible structure-linkage relationship; characterized in that said hydrogel cushion layer comprising a multiple of hydrophilic structure-linkage fibers and a multiple of hydrogel micro balls, said hydrophilic structure-linkage fiber adsorbs side by side with said hydrogel micro ball in said hydrogel cushion layer; and said hydrogel cushion layer is supported by a hydrophilic structure-linkage network forming through a network connection among said hydrophilic structure-linkage fibers and said hydrophilic structure-linkage fibers, wherein said network connection comprising a first partial connection occurring into said structure-linkage holes, a second partial connection surrounding said structure-linkage holes, and a third connection linking said first partial connection and said second partial connection to form said structure-linkage multi-dimensional flexible structure-linkage relationship; and a multiple of hydrophilic microsphere is positioned in said hydrogel cushion layer, wherein said hydrophilic microsphere adsorbs side by side with said hydrogel micro ball, and adsorbs side by side with said hydrophilic structure-linkage fiber, resulting in a consolidated structure of said hydrogel cushion layer.

    2. A hydrogel surgical dressing product as claimed in claim 1, wherein said hydrophilic structure-linkage fiber comprising a material selected from a group of polymethacrylate, polymethacrylate derivative, polysiloxane derivative, carboxymethylcellulose, alginate, polycarbohydrate, hyaluronic acid, collagen, vegetative protein, gelatin, polylactides, polyethylene pyrrole, polyethylene glycol, and thereof.

    3. A hydrogel surgical dressing product as claimed in claim 1, wherein said hydrogel micro ball comprising a material selected from a group of polymethacrylate, polymethacrylate derivative, polysiloxane derivative, carboxymethylcellulose, alginate, polycarbohydrate, hyaluronic acid, collagen, the vegetative protein, gelatin, polylactides, polyethylene pyrrole, polyethylene glycol, and thereof.

    4. A hydrogel surgical dressing product as claimed in claim 1, wherein said hydrophilic microsphere comprising a material selected from a group of amino acid, water, oxygen, ethyl alcohol, propyl alcohol, glycerine, small molecular water-soluble polymethyl acrylic acid derivative, small molecular polysiloxane derivative, small molecular carboxymethylcellulose, small molecular alginate, small member carbohydrate, small molecular uric acid, small molecular collagen, small molecular vegetative protein, small molecular gelatin, small molecular polylactate, small molecular polyethylene pyrrole, small molecular polyethylene glycol, peptide and thereof.

    5. A hydrogel surgical dressing product as claimed in claim 1, wherein said multi-dimensional flexible hydrophilic structure-linkage composite prepared from materials chosen from the combination of one of the groups of polyvinyl-chloride, polyethylene, ethylene vinyl acetate copolymer, polyvinyl alcohol, polyurethane, polypropylene or polyethylene, Teflon, polysiloxane, polylactate derivatives, water-soluble polymethacrylic acid derivatives, cellulose derivatives, chitosan derivatives, carbon fiber derivatives and thereof.

    6. A hydrogel surgical dressing product as claimed in claim 1, wherein said structure-linkage holes are round.

    Description

    BRIEF DESCRIPTION OF THE DRAWINGS

    [0017] To further clarify various aspects of some embodiments of the present invention, a more particular description of the invention will be rendered by references to specific embodiments thereof, which are illustrated in the appended drawings. It is appreciated that these drawings depict only typical embodiments of the invention and are therefore not to be considered limiting of its scope. The invention will be described and explained with additional specificity and detail through the accompanying drawings in which:

    [0018] FIG. 1 illustrates a perspective view of the hydrogel surgical dressing product with a multi-dimensional flexible hydrophilic structure-linkage composite.

    [0019] FIG. 2 illustrates (A) a cross-sectional view of the wound dressing product in the clinical application and (B) a perspective view of a joint region in clinic treatment.

    DETAILED DESCRIPTION OF THE INVENTION

    [0020] The present invention will now be illustrated by the following examples, which are illustrative of, but not restrictive of, the present invention.

    DESCRIPTION OF NOTATION

    [0021] 1 a hydrogel surgical dressing [0022] 10 a multi-dimensional flexible hydrophilic structure-linkage composite [0023] 13 a hydrophilic multi-dimensional flexible structure-linkage membrane [0024] 15 a structure-linkage hole [0025] 20 a hydrogel cushion layer [0026] 23 a hydrophilic structure-linkage fiber [0027] 25 a hydrogel micro ball [0028] 30 a hydrophilic microsphere [0029] 100 a multi-dimensional flexible protecting film [0030] 1000 wound [0031] 2000 a joint region

    Example 1

    [0032] The present invention provides a hydrogel surgical dressing 1 having a multi-dimensional flexible hydrophilic structure-linkage composite 10, as shown in FIG. 1, comprising: a hydrogel cushion layer 20, and a multi-dimensional flexible hydrophilic structure-linkage composite, wherein said multi-dimensional flexible hydrophilic structure-linkage composite 10 comprising a hydrophilic multi-dimensional flexible structure-linkage membrane 13, and a multiple of structure-linkage holes 15 positioned into said hydrophilic multi-dimensional flexible structure-linkage membrane 13, and the sizes of structure-linkage holes 15 change with the degree of compelling force, resulting in a multi-dimensional flexible structure-linkage relationship. Said hydrogel cushion layer 20 comprising a multiple of hydrophilic structure-linkage fibers 23 and a multiple of hydrogel micro balls 25, said hydrophilic structure-linkage fiber 23 adsorbs side by side with said hydrogel micro ball in said hydrogel cushion layer 20; and said hydrogel cushion layer 20 is supported by a hydrophilic structure-linkage network forming through a network connection among said hydrophilic structure-linkage fibers 23 and said hydrophilic structure-linkage fibers 23, wherein said network connection comprising a first partial connection occurring into said structure-linkage holes 15, a second partial connection surrounding said structure-linkage holes 15, and a third connection linking said first partial connection and said second partial connection to form said multi-dimensional flexible structure-linkage relationship. Said hydrogel cushion layer comprises a multiple of hydrophilic microsphere 30 positioned in said hydrogel cushion layer 20, wherein said hydrophilic microsphere 30 adsorbs side by side with said hydrogel micro ball 25, and adsorbs side by side with said hydrophilic structure-linkage fiber 23, resulting in a consolidated structure of said hydrogel cushion layer 20. Because of the structure prepared from at least two kinds of polymeric network, the hydrophilic structure-linkage network preferably belongs to a kind of interpenetrating polymeric network or semi-interpenetrating polymer network. In the specific application, said hydrophilic microsphere 30 could be movably in said hydrophilic structure-linkage network. The mobility and efficiency of said hydrophilic microsphere 30 could be controlled by the size of said hydrophilic structure-linkage network. Preferably, said hydrophilic structure-linkage fiber 23 comprising a material selected from a group of polymethacrylate, polymethacrylate derivative, polysiloxane derivative, carboxymethylcellulose, alginate, polycarbohydrate, hyaluronic acid, collagen, vegetative protein, gelatin, polylactides, polyethylene pyrrole, polyethylene glycol, and thereof. Preferably, said hydrogel micro ball 25 comprising a material selected from a group of polymethacrylate, polymethacrylate derivative, polysiloxane derivative, carboxymethylcellulose, alginate, polycarbohydrate, hyaluronic acid, collagen, vegetative protein, gelatin, polylactides, polyethylene pyrrole, polyethylene glycol, and thereof. Preferably, said hydrophilic microspherel 30 comprising a material selected from a group of amino acid, water, oxygen, ethyl alcohol, propyl alcohol, glycerine, small molecular water-soluble polymethyl acrylic acid derivative, small molecular polysiloxane derivative, small molecular carboxymethylcellulose, small molecular alginate, small member carbohydrate, small molecular Bolivian uric acid, small molecular collagen, small molecular vegetative protein, small molecular gelatin, small molecular polylactate, small molecular polyethylene pyrrole, small molecular polyethylene glycol, peptide and thereof. Preferably, said structure-linkage holes are round. Preferably, this multi-dimensional flexible hydrophilic structure-linkage composite 10 was prepared from materials chosen from the combination of one of the groups of polyvinyl-chloride, polyethylene, ethylene vinyl acetate copolymer, polyvinyl alcohol, polyurethane, polypropylene or polyethylene, Teflon (PTFE), polysiloxane, polylactate derivatives, water-soluble polymethacrylic acid derivatives, cellulose derivatives, chitosan derivatives, carbon fiber derivatives and thereof. Particularly, the hydrogel surgical dressing 1 having a multi-dimensional flexible hydrophilic structure-linkage composite 10 is employed in clinical applications (see FIG. 2), the hydrogel surgical dressing 1 would contact with a target wound 1000. A multiple dimension flexible protecting film would be employed with said hydrogel surgical dressing 1 to fix said hydrogel surgical dressing 1 to cover said target wound 1000. At the same time, said multiple dimension flexible protecting film has to avoid contact with said target wound 1000. Said hydrophilic microsphere 30 could be movable in said hydrophilic structure-linkage network and employed to carry a nutrient, an enzyme, a growth factor, tissue, metabolite, etc. The mobility and carrying efficiency of said hydrophilic microsphere 30 could be controlled by the size of said hydrophilic structure-linkage network. The present invention provides a designed multi-dimensional flexible hydrophilic structure-linkage module in a hydrogel surgical dressing product to solve the clinical problems of traditional hydrogel dressings, in particular, falling off situation happening after swelling with water or tissue fluid in medical applications. The designed multi-dimensional flexible hydrophilic structure-linkage module provides a multi-dimensional flexible structure-linkage relationship of each parts of said hydrogel surgical dressing 10 instead of the traditional design of multiple adhering layers. The force inducing falling off situation could be dispersing into the multi-dimensional flexible hydrophilic structure-linkage composite. For example, medical treatments of a joint region 2000 was carried out.

    [0033] Having described the invention in detail and by reference to preferred embodiments thereof, it will be apparent that modifications and variations are possible without departing from the scope of the invention which is defined in the appended claims.