Oil-in-water emulsions of which the oil phase is in the form of a mixture of drops of different sizes

Abstract

The present invention relates to a composition, in particular cosmetic, in the form of an oil-in-water emulsion, comprising a continuous aqueous phase and a dispersed oil phase in the form of drops (G1) and drops (G2), wherein the size of the drops (G1) is less than 500 ?m and the size of the drops (G2) is greater than 500 ?m.

Claims

1. A composition in the form of an oil-in-water emulsion, comprising a continuous aqueous phase and a dispersed oil phase in the form of drops (G1) and (G2), wherein the drops (G1) comprise an oil phase and a shell formed of at least one anionic polymer (PA1) and at least one cationic polymer (PC1), wherein the size of the drops (G1) is less than 500 ?m, wherein the drops (G2) comprise an oil phase and a shell, said shell being formed of at least one anionic polymer (PA2), identical to or different from (PA1), and at least one cationic polymer (PC2), identical or different from (PC1), wherein the size of the drops (G2) is greater than 500 ?m, wherein the drops (G1) and (G2) are different in nature, in regard to the nature of the anionic and cationic polymers, or oils and/or additional compounds and/or active agents wherein the anionic polymers (PA1) and (PA2) are hydrophilic, and the cationic polymers (PC1) and (PC2) are liposoluble, and wherein the composition does not include a surfactant.

2. The composition according to claim 1, wherein the oil phase of the drops (G2) comprises at least one gelling agent.

3. The composition according to claim 1, wherein the oil phase of the drops (G1) and/or drops (G2) comprises at least one oil (H1) selected from the group consisting of hydrocarbon-based oils of animal origin, synthetic esters and ethers, linear or branched hydrocarbons of mineral or synthetic origin, silicone oils, fatty alcohols having from 8 to 26 carbon atoms, fluorinated oils partially hydrocarbonated and/or siliconated and their mixtures.

4. The composition according to claim 1, wherein the anionic polymers (PA1) and (PA2), which are identical or different, are polymers comprising monomeric units comprising at least one carboxylic acid function.

5. The composition according to claim 1, wherein the composition comprises from 0.01% to 10% by weight of anionic polymer(s) (PA1) and (PA2), relative to the total weight of the composition.

6. The composition according to claim 1, wherein the cationic polymers (PC1) and (PC2), identical or different, have the following formula: ##STR00004## in which: R.sub.1, R.sub.2 and R.sub.3, independently of each other, represent OH or CH.sub.3; R.sub.4 represents a CH.sub.2group or a XNHgroup in which X is a divalent alkylene radical with C3 or C4; x is an integer from 10 to 5000; y is an integer between 2 and 1000; and z is an integer between 0 and 10.

7. The composition according to claim 1, wherein the drops (G1) and (G2) comprise from 0.01% to 10% by weight of cationic polymer(s) (PC1) and (PC2), relative to the total weight of the oil phase of the drops (G1) and (G2).

8. The composition according to claim 2, wherein the drop gelling agent (G2) is selected from the group consisting of organic, inorganic, polymeric or molecular lipophilic gelling agents; fatty substances that are solid at room temperature and pressure; and their mixtures.

9. The composition according to claim 8 wherein the gelling agent is selected from the group consisting of polyacrylates, dextrin and fatty acid esters, esters of glycerol and fatty acid(s), polyamides, and mixtures thereof.

10. The composition according to claim 9, wherein the dextrin and fatty acid esters are selected from the group consisting of dextrin palmitates, dextrin myristates, dextrin palmitates/ethylhexanoates, and mixtures thereof.

11. The composition according to claim 8, wherein the gelling agent is selected from the group consisting of modified clays, silicas and mixtures thereof.

12. The composition according to claim 1, wherein the composition comprises a weight ratio drops (G1)/drops (G2) of between 0.03 and 50.

13. The composition according to claim 1, further comprising at least one active agent selected from hydrating agents, healing agents, depigmenting agents, UV filters, desquamating agents, antioxidants, agents stimulating the synthesis of dermal and/or epidermal macromolecular agents, contracting agents, antiperspirants, soothing agents, anti-aging agents, perfuming agents and mixtures thereof.

14. The composition according to claim 1, characterized in that the drops (G1) and/or (G2) further comprise at least one coloring agent.

15. The composition according to claim 1, wherein the composition comprises more than 10% by weight of oil phase relative to the total weight of the composition.

16. A composition in the form of an oil-in-water emulsion, comprising a continuous aqueous phase and a dispersed oil phase in the form of drops (G1) and (G2), wherein the drops (G1) comprise an oil phase and a shell formed of at least one anionic polymer (PA1) and at least one cationic polymer (PC1), wherein the size of the drops (G1) is less than 500 ?m, wherein the drops (G2) comprise an oil phase and a shell, said shell being formed of at least one anionic polymer (PA2), identical to or different from (PA1), and at least one cationic polymer (PC2), identical or different from (PC1), wherein the size of the drops (G2) is greater than 500 ?m, and wherein the drops (G1) and (G2) are different in nature, in regard to the nature of the anionic and cationic polymers, or oils and/or additional compounds and/or active agents, wherein the anionic polymers (PA1) and (PA2) are hydrophilic, and the cationic polymers (PC1) and (PC2) are lipophilic or liposoluble, wherein the anionic polymer (PA1) is selected from the group consisting of carbomers and copolymers of acrylic acid or maleic acid and other monomers, said other monomers being selected from the group consisting of: acrylamide, alkyl acrylates, C.sub.5-C.sub.8 alkyl acrylates, C.sub.10-C.sub.30 alkyl acrylates, C.sub.12-C.sub.22 alkyl methacrylates, methoxy-polyethylene glycol methacrylates, hydroxyester acrylates, crosspolymer acrylates, and mixtures thereof, and the composition does not include a surfactant.

17. The composition of claim 16, wherein the anionic polymer (PA1) is selected from the group consisting of carbomers and crosslinked acrylates/C.sub.10-30 alkyl acrylate copolymers.

18. The composition of claim 16, wherein the anionic polymer (PA1) is a carbomer.

19. The composition of claim 1, wherein at least one of the cationic polymers (PC1) and (PC2) is amodimethicone.

20. The composition of claim 16, wherein at least one of the cationic polymers (PC1) and (PC2) is amodimethicone.

Description

EXAMPLES

Example 1: Surfactants/Gelled Drops (G2) Compatibility

(1) The present study aims to evaluate the compatibility of gelled drops (G2) according to the invention in contact with two surfactants commonly used in the aqueous phases of cosmetic creams.

(2) The drops (G2) considered in this study are stained blue for visualization in surfactant solutions and in creams. These gelled drops (G2) were obtained by means of a hot microfluidic device (about 80? C.) as described in FR1558850 by implementing the aqueous and oil phases described in the table below:

(3) TABLE-US-00001 % w/w Name INCI name PHASES % w/w AQUEOUS PHASE Osmosis water Water 87.59 78.84 Microcare PE Phenoxyethanol 0.89 0.80 Microcare PTG Pentylenglycol 2.22 2.00 Tego Carbomer 340 FD Carbomer 0.22 0.20 Glycerine codex (99%) Glycerin 9.00 8.10 EDETA BD Disodium EDTA 0.036 0.03 Sodium Hydroxide Sodium Hydroxide 0.033 0.03 Pellets PRS codex 100.00 90.00 OILY PHASE DUB ININ Isononyl 84.50 8.45 Isononanoate Rheopearl KL2 Dextrin Palmitate 15.00 1.50 Phat Blue DC6204 CI 61565, CI 60725 0.0039 0.00039 KF 8004 Amodimethicone 0.50 0.05 100.00 10.00

(4) Once the emulsion was made, the gelled drops (G2) were isolated from the aqueous phase by filtration before the tests described below.

(5) The gelled drops (G2) obtained thus have the following composition:

(6) TABLE-US-00002 Drops (G2) DUB ININ Isononyl Isononanoate 84.50 Rheopearl KL2 Dextrin Palmitate 15.00 Phat Blue DC6204 CI 61565, CI 60725 0.0039 KF 8004 Amodimethicone 0.50 Tego Carbomer 340 FD Carbomer * Total 100.00 *The carbomer used is present in the drops (G2) only at the level of the membrane and therefore in a non-quantifiable manner.

(7) ATest with Two Surfactants

(8) The behavior of the gelled drops (G2) is studied in the presence of the two surfactants, namely Montanov 68 EC and Simulsol 165.

(9) For this purpose, the four compositions described in the two tables below are prepared:

(10) TABLE-US-00003 Name INCI name % w/w Osmosis water Water Qsp* Microcare PE Phenoxyethanol 0.39 Microcare PTG Pentylenglycol 0.97 Tego Carbomer Carbomer 0.06 340FD EDETA BD Disodium EDTA 0.01 Sodium Hydroxide Sodium Hydroxide 0.01 Pellets PRS codex TENSIOACTIF (Cetearyl alcohol & Cetearyl glucoside) 2-10 (Montanov 68 EC OR OU Simulsol 165) (PEG 100 Stearate & Glyceryl Stearate) Drops (G2) Isononyl Isononanoate, CI 61565, CI 5.00 60725, coacervate (amodimethicone + carbomer), Dextrin Palmitate Total 100.00 *qsp: sufficient quantity for

(11) with:

(12) TABLE-US-00004 Composition No. 183 2% Montanov 68 EC 184 7% Montanov 68 EC 185 5% Simulsol 165 186 10% Simulsol 165

(13) The drops (G2) were incorporated into these compositions by manual mixing with a spatula for 30 seconds. The stability of the drops (G2) for these formulas 183, 184, 185 and 186 was observed for 1 month at room temperature (RT) and 50? C. The objective of the test at 50? C. is to bring the composition under consideration into accelerated aging conditions.

(14) Results

(15) TABLE-US-00005 Composition T? C. VISUAL OBSERVATIONS TEXTURE of drops (G2) 183 TA G2 blue, spherical, suspended The G2 spread well on the (2% in the continuous phase skin. Montanov 50? C. G2 blue, spherical, smaller G2 more resistant (=more 68 EC) than TA, suspended in the viscous gelled oil); more viscous continuous spread more with more phase. difficulty. 184 TA G2 blue, spherical, suspended The G2 spread well on the (7% in the continuous phase. skin. Montanov 50? C. G2 blue, spherical, smaller G2 more resistant (=more 68 EC) than TA, suspended in the viscous gelled oil); more viscous continuous spread more with more phase. difficulty. 185 TA G2 blue, spherical, which The G2 spread well on the (5% cream on the surface of the skin. Simulsol continuous phase. 165) 50? C. G2 blue-green, spherical, G2 harder and some are smaller than TA and which solid grains difficult to cream faster than TA. remove. 186 TA G2 blue, spherical, suspended The G2 spread well on the (10% in the continuous phase. skin. Simulsol 50? C. G2 green-blue, spherical, G2 harder and some are 165) even smaller than 185 at 50? C. solid grains difficult to and which cream on the remove. surface of the continuous phase.

(16) In general, it is found that the size of the drops (G2) decreases over time while their viscosity increases when the compositions are maintained at 50? C.

(17) BTest in Three Rich Creams

(18) In the same manner as in the aforementioned compositions, the above drops (G2) are incorporated at 10% into 3 different rich creams: CNBC-1; CNBC-2; CNBC-3.

(19) Composition of Rich Cream CNBC-1

(20) TABLE-US-00006 Name INCI name % w/w Osmosis water Water qsp Microcare PE Phenoxyethanol 0.8 Microcare PTG Pentylenglycol 2.0 Keltrol CGT Xanthan Gum 0.3 Glycerin Glycerin 3.0 Montanov 68 EC Cetearyl alcohol & Cetearyl glucoside 8.0 Miglyol 812 N Caprylic/Capric Triglyceride 15.0 Lipex Shea Butyrospermum Parkii (Shea) Butter 2.0 JAUNE COVARINE CI 11710 (and) Glycerin (and) Aqua 0.1 W 1793 (and) Sodium Laureth Sulfate Total 100.00 * qsp: sufficient quantity for

(21) Composition of Rich Cream CNBC-2

(22) TABLE-US-00007 Name INCI name % w/w Osmosis water Water qsp Microcare PE Phenoxyethanol 0.8 Microcare PTG Pentylenglycol 2.0 Satiaxane CX 911 Xanthan Gum 0.3 Glycerin Glycerin 5.0 Simulsol 165 PEG 100 Stearate & Glyceryl Stearate 4.0 Lipex 102 Butyrospermum Parkii (Shea) Butter 7.0 Lanette 22 Behenyl alcohol 2.0 Sweet Almond Oil Prunus Amygdalus Dulcis (Sweet 12.0 Almond) Oil ROUGE COVARINE CI 73360 (and) Glycerin (and) Aqua 0.1 W 3792 (and) PVP Total 100.00 * qsp: sufficient quantity for

(23) Composition of Rich Cream CNBC-3

(24) TABLE-US-00008 % Name INCI name w/w Osmosis water Water qsp Microcare PE Phenoxyethanol 0.8 Microcare PTG Pentylenglycol 2.0 Keltrol CGT Xanthan Gum 0.3 Glycerin Glycerin 3.0 Montanov 68 EC Cetearyl alcohol & Cetearyl glucoside 5.0 Lanette 22 Behenyl Alcohol 13.0 Lipex L'sens Soybean Glycerides (and) Butyrospermum 2.0 Parkii Butter Unsaponifiables BLEU COVARINE CI 74160 (and) Glycerin (and) Aqua 0.1 W 6795 (and) Sodium Laureth Sulfate Total 100.00 * qsp: sufficient quantity for

(25) The stability of the drops (G2) in these 3 compositions was also studied for 1 month at ambient temperature (RT) and 50? C.

(26) Results

(27) TABLE-US-00009 Sample T? C. VISUAL OBSERVATIONS TEXTURE CNBC-1 TA G2 blue, spherical; Representative of rich Orange cream cream CNBC-1 50? C. G2 blue, spherical, but with a Hardened cream, very slight decrease in size; consistent with the Orange cream sample, some solid grains upon application (=G2 harder) CNBC-2 TA G2 blue, spherical; Representative of rich Pink cream cream CNBC-2 50? C. G2 much less blue than TA, All G2 have become spherical, with a decrease in small, solid grains). The size; Pink cream cream is more fluid on application than TA. CNBC-3 TA G2 blue, spherical; Representative of rich Bluish cream cream CNBC-3 50? C. G2 blue, spherical; The G2 are more Bluish cream tending towards noticeable than TA; green (yellowing) isolated, the drops (G2) feel more consistent than at TA. Again, there is a tendency for drops (G2) to become smaller and stronger at 50? C.

(28) Conclusion

(29) The present study shows that the size of the drops (G2) decreases over time while their viscosity/hardness increases (increase of the local concentration of oily gelling agent) when the latter are in the presence of surfactants or compositions comprising them.

(30) This phenomenon is characterized by a compositional maturation resulting in a migration of a part of the oily phase of the drops (G2) to the surfactants located in the continuous phase of the creams. This has the effect of strongly degrading the organoleptic properties of the composition comprising drops (G2).

(31) Given the stability constraints over time required in the cosmetics field, these results show the impossibility of using drops (G2) in conventional cosmetic compositions (i.e. including surfactants).

Example 2: Preparation of a Composition According to the Invention with Procedure No. 1

(32) A composition according to the invention was prepared by mixing, on the one hand, an emulsion (E1) comprising drops (G1) and, on the other hand, an emulsion (E2) comprising gelled drops (G2).

(33) 1. Preparation of the Emulsion (E1)

(34) a. Preparation of a Premix: Lauroyl Lysine was added to the glycerin with stirring, then the mixture was stirred for 10 minutes and the absence of agglomerates was checked.

(35) b. Preparation of a 10% sodium hydroxide solution: sodium hydroxide and osmosis water were mixed and then stirred for 10 minutes; and the homogeneity of the solution thus obtained was checked.

(36) c. Preparation of the aqueous phase (OFI): the osmosis water was then incorporated, followed by phenoxyethanol, and then pentylene glycol and then disodium EDTA; the carbomer TEGO CARBOMER 340 FD and CARBOPOL ULTREZ 21 POLYMER were sprinkled on the surface; it was allowed to stand until the total hydration of the carbomers (20-30 minutes) and mixed with stirring using a deflocculator; it was stirred until the total solubilization of the carbomers (about 30 minutes); the aforementioned premix (a.) was incorporated then the whole was stirred for 10 minutes; the above-mentioned sodium hydroxide solution (b.) was added and then the whole was stirred for 10 minutes; and the homogeneity of the solution was verified.

(37) The aqueous phase (OFI) thus obtained comprises the following constituents:

(38) TABLE-US-00010 Name INCI name % w/w Osmosis water Water qsp MICROCARE PE Phenoxyethanol 1.2346 MICROCARE Pentyleneglycol 2.7435 EMOLLIENT PTG TEGO CARBOMER Carbomer 0.2333 340 FD CARBOPOL ULTREZ Acrylates/C10-30 Alkyl 0.50 21 POLYMER Acrylate Crosspolymer GLYCERINE CODEX Glycerin 12.3457 EDETA BD Disodium EDTA 0.0412 AMIHOPE? LL Lauroyl Lysine 3.7037 SOLUTION SOUDE ? 10% Sodium Hydroxide 0.1 Total 100.00 * qsp: sufficient quantity for

(39) d. Preparation of the oily phase (IFI): the amodimethicone and the isononyl isononanoate were incorporated, then the whole was gently stirred without incorporating any air bubbles; the homogeneity of the solution was verified; the octyldodecanol was incorporated and then stirred for 3 minutes; PLANTEC REFINED SHEA BUTTER was incorporated; the mixture thus obtained was heated with stirring to 60? C. for 5 minutes, then the homogeneity of the solution was checked; a perfume was incorporated and then stirred for 3 minutes; the homogeneity of the solution was verified.

(40) The oily phase (IFI) thus obtained comprises the following constituents:

(41) TABLE-US-00011 Name INCI name % w/w ISONONANOATE Isononyl Isononanoate qsp D'ISONONYLE - DUB ININ EUTANOL G Octyldodecanol 19 PLANTEC REFINED Butyrospermum Parkii 19 SHEA BUTTER Perfume Perfume 3.33 CAS-3131 Amodimethicone 0.2 Total 100.00

(42) a Preparation of the basic solution (BFI): sodium hydroxide and osmosis water were mixed and then stirred for 10 minutes; and the homogeneity of the solution thus obtained was checked.

(43) The basic solution (BFI) thus obtained comprises the following constituents:

(44) TABLE-US-00012 Name INCI name % w/w OSMOSIS WATER Water 89.90 SOLUTION MIXED to 10% Sodium Hydroxide 10.10 Total 100.00

(45) f. Preparation of the emulsion (E1):

(46) To prepare this emulsion, 10% by weight of oily phase (IFI), 81% of aqueous phase (OFI) and 9% of basic solution (BFI) were used: the aqueous phase (OFI) was weighed as described above; the oil phase (IFI) was weighed as described above; the oil phase and the aqueous phase were then separately placed in a water bath at 60? C. for about 15 minutes, while checking that the temperature of the two phases was the same; the aqueous phase was stirred; the oil phase is progressively incorporated; the stirring speed was gradually increased so as to always have a vortex; then stirred for 15 minutes; it was then cooled to room temperature with stirring; the ethanol was added with stirring; after 10 minutes of stirring, the basic solution (BFI) was incorporated and the stirring speed was gradually increased so as to always have a vortex; finally, the mixture was stirred for 15 minutes while cooling the mixture with a cold water bath.

(47) The final emulsion (E1) thus obtained comprises the following ingredients:

(48) TABLE-US-00013 AQUEOUS PHASE GEL % w/w % w/w Name INCI name phases final Osmosis water Water qsp qsp Microcare PE Phenoxyethanol 1.11 1.00 Microcare PTG Pentylenglycol 2.47 2.22 Tego Carbomer Carbomer 0.21 0.19 340 FD Carbopol Ultrez Acrylates/C10-30 0.45 0.405 21 Polymer Alkyl Acrylate Crosspolymer Glycerine codex Glycerin 11.11 10.00 (99%) EDETA BD Disodium EDTA 0.04 0.033 AMIHOPE? LL Lauroyl Lysine 3.33 3.00 Denatured ethyl Ethanol 5.56 5.00 alcohol BITREX/ TBA Sodium Hydroxide Sodium Hydroxide 0.11 0.008 Pellets PRS codex

(49) 2. Preparation of the Emulsion (E2)

(50) a. Preparation of a 10% Sodium Hydroxide Solution: sodium hydroxide and osmosis water were mixed and then stirred for 10 minutes; and the homogeneity of the solution thus obtained was checked.

(51) b. Preparation of the Aqueous Phase (OF2): osmosis water, phenoxyethanol, pentylene glycol, and disodium EDTA were incorporated; the carbomer TEGO CARBOMER 340 FD was sprinkled on the surface; it was allowed to stand until the total hydration of the carbomer (about 20-30 minutes) and then put together with stirring using a deflocculator; it was stirred until complete solubilization of the carbomer (about 30 minutes) and glycerine was incorporated; the whole was then stirred for 5 minutes; the above-mentioned sodium hydroxide solution (a) was added and then the whole was stirred for 10 minutes; and the homogeneity of the solution has been verified.

(52) The aqueous phase (OF2) thus obtained comprises the following constituents:

(53) TABLE-US-00014 Name INCI name % w/w Osmosis water Water qsp Microcare PE Phenoxyethanol 0.89 Microcare PTG Pentylenglycol 2.22 Tego Carbomer 340 FD Carbomer 0.22 Glycerine codex (99%) Glycerin 9.00 EDETA BD Disodium EDTA 0.036 Sodium Hydroxide Sodium Hydroxide 0.033 Pellets PRS codex 100.00

(54) c. Preparation of the Oil Phase (IF2): the amodimethicone and the isononyl isononanoate were incorporated and the mixture was gently agitated without incorporating any air bubbles; this mixture was heated to 80? C.; dextrin palmitate was incorporated while maintaining the temperature; it was stirred for 30 minutes; the homogeneity of the solution was verified.

(55) The oil phase (IF2) thus obtained comprises the following constituents:

(56) TABLE-US-00015 Name INCI name % w/w DUB ININ Isononyl Isononanoate qsp Rheopearl KL2 Dextrin Palmitate 15.00 CAS-3131 Amodimethicone 0.20 100.00

(57) d. Preparation of the Emulsion (E2):

(58) The emulsion (E2) is prepared according to a hot microfluidic process (approximately 80? C.), in particular as described in application FR1558850.

(59) TABLE-US-00016 OF2 150 IF2 20

(60) The final emulsion (E2) thus obtained, comprising monodisperse gelled drops (G2) with a diameter of approximately 800 ?m, comprises the following ingredients:

(61) TABLE-US-00017 % w/w % w/w Name INCI name phases Final AQUEOUS PHASE Osmosis water Water 87.5973 78.84 Microcare PE Phenoxyethanol 0.8889 0.80 Microcare PTG Pentylenglycol 2.2222 2.00 Tego Carbomer 340 FD Carbomer 0.2222 0.20 Glycerine codex (99%) Glycerin 9.00 8.10 EDETA BD Disodium EDTA 0.0360 0.03 Sodium Hydroxide Sodium Hydroxide 0.0333 0.030 Pellets PRS codex 100.00 90.00 OIL PHASE DUB ININ Isononyl Isononanoate 84.80 8.48 Rheopearl KL2 Dextrin Palmitate 15.00 1.50 CAS-3131 Amodimethicone 0.20 0.02 100.00 10.00

(62) 3. Preparation of the Composition According to the Invention

(63) The composition according to the invention was then obtained by mixing the above-mentioned emulsions (E1) and (E2) as described below.

(64) The emulsion (E2) was filtered using a strainer or sieve whose pore size is smaller than the diameter of the drops (G2) so as to eliminate all or part of the aqueous phase (OF2). The drops (G2) in the colander are then removed to be introduced into the emulsion (E1) with gentle stirring.

(65) Depending on the desired visual aspect and texture, the ratio E1/E2 in mass varies; thus, the drops (G2) may represent between 1% and 20%, or even between 5% and 15%, by weight relative to the total weight of the composition according to the invention.

Example 3: Preparation of a Composition According to the Invention with Procedure No. 2

(66) A procedure for preparing a composition according to the invention described in this example 3 differs from that described in Example 2 in that the gelled drops (G2) are manufactured directly from an emulsion (E1).

(67) 1. Preparation of the Emulsion (E1)

(68) This is the emulsion (E1) described in Example 2 above but which differs by: the absence of basic solution (BFI), so as to maintain the very fluid nature of this emulsion (E1). Thus, the emulsion (E1) has a viscosity of less than 3000 cPs, as measured at 25? C. according to the measurement protocol relating thereto and described above. the addition of CREASPERSE IRON BLUE in the oil phase (IFI) at the end of the preparation protocol of the latter, with homogenization for 5 minutes.

(69) The final emulsion (E1) thus obtained comprises the following ingredients:

(70) TABLE-US-00018 % w/w % w/w Name INCI name Phases final AQUEOUS PHASE GEL Osmosis water Water qsp qsp Microcare PE Phenoxyethanol 1.11 1.00 Microcare PTG Pentylenglycol 2.47 2.222 Teqo Carbomer Carbomer 0.210 0.89 340 FD Carbopol Ultrez Acrylates/C10-30 0.45 0.405 21 Polymer Alkyl Acrylate Crosspolymer Glycerine codex Glycerin 11.11 10.00 (99%) EDETA BD Disodium EDTA 0.04 0.033 AMIHOPE? LL Lauroyl Lysine 3.33 3.00 Denatured ethyl Ethanol 5.56 5.00 alcohol BITREX/ TBA Sodium Hydroxide Sodium Hydroxide 0.1 0.008 Pellets PRS codex OIL PHASE DUB ININ Isononyl Isononanoate 58.47 5.847 EUTANOL G Octyldodecanol 19.00 1.90 PLANTEC REFINED Butyrospermum Parkii 19.00 1.90 SHEA BUTTER CREASPERSE CI 77510 (and) 0.004 0.0036 IRON BLUE Hydrogenated Polydecene (and) Hydroxystearic Acid Perfume Perfume 3.33 0.333 CAS-3131 Amodimethicone 0.20 0.02

(71) 2. Preparation of the Composition According to the Invention

(72) The composition according to the invention is prepared according to a hot microfluidic process (approximately 80? C.), in particular as described in the application FR1558850 using the emulsion (E1) above as aqueous phase (OF) and the oil phase (IF2) described below for the formation of drops (G2).

(73) TABLE-US-00019 OIL PHASE (IF2) DUB ININ Isononyl Isononanoate qsp Rheopearl KL2 Dextrin Palmitate 15.00 CREASPERSE CI 77510 (and) Hydrogenated 0.01 IRON BLUE Polydecene (and) Hydroxystearic Acid CAS-3131 Amodimethicone 0.20 TOTAL 100.00

(74) The composition according to the invention is prepared according to a hot microfluidic process (approximately 80? C.), in particular as described in the application FR1558850.

(75) The flow rates considered (in mL/h) for this reason are the following:

(76) TABLE-US-00020 OF (=emulsion (E1) 150 IF2 20

(77) The manufacture of the drops (G2) is therefore simultaneous with the manufacture of the composition according to the invention. At the end of the manufacture of this composition, a base solution (BFI), identical to that described in Example 2, may be added, preferably microfluidically, so as to enhance the viscosity of the aqueous phase in the composition according to the invention, and thus suspend the drops (G2).

(78) The compositions according to the invention presented in Examples 2 and 3 are particularly advantageous visually and sensorially. Visually, the consumer is faced with compositions comprising drops (G2) visible to the naked eye. On the sensory level, the texture of these compositions is evolutionary. The first moments of application are very aqueous with a marked brittle effect. Then, the feeling evolves towards an oily veil that fades to leave a light and hydrated skin. In parallel, we feel the gelled drops (G2) melt under the effect of spreading which provides an enhanced oily effect.

Example 4: Preparation of a Transparent Composition According to the Invention with Procedure No. 2

(79) The composition of Example 4 differs from that described in Example 3 in that the continuous aqueous phase and the drops (G1) and (G2) are transparent and the oil phase of the drops (G2) is devoid of gelling agent.

(80) 1. Preparation of the Emulsion (E1)

(81) TABLE-US-00021 Name INCI name % w/w Aqueous phase (OFI) Osmosis water Water qsp MICROCARE PE PHENOXYETHANOL, 0.73 AQUA MICROCARE PENTYLENE 1.82 EMOLLIENT PTG GLYCOL, AQUA CARBOPOL ETD CARBOMER 0.13 2050 POLYMER GLYCERINE CODEX GLYCERIN, AQUA 22.76 ZEMEA PROPANEDIOL PROPANEDIOL 13.65 CARBOPOL ULTREZ Carbomer 0.13 30 NIACINAMIDE PC Niacinamide 4.55 EDETA BD DISODIUM EDTA 0.038 Oil phase (IFI) CSF-3100 Dimethicone 10.63 Perfume Fragrance 0.35 CAS-3131 Amodimethicone 0.02 TOTAL 100

(82) 2. Preparation of the Composition According to the Invention

(83) The oil phase (IF2) for drop formation (G2) is described below.

(84) TABLE-US-00022 OIL PHASE (IF2) DUB ININ Isononyl Isononanoate qsp Rheopearl KL2 Dextrin palmitate 0 or 15 (optional) CREASPERSE CI 77510 (and) 0 or 0.01 IRON BLUE (optional) Hydrogenated Polydecene (and) Hydroxystearic Acid CAS-3131 Amodimethicone 0.20 TOTAL 100.00

(85) Optionally, the oil phase (IF2) may further comprise at least one gelling agent and/or a coloring agent so as to affect the visual aspect of the drop (G2).

(86) When the IF2 is devoid of gelling agent, the procedure for preparing the composition according to Example 4 differs from that described in Example 3 in that it is carried out at room temperature; wherein this procedure may therefore advantageously require the use of an intermediate fluid (FI) comprising only Isononyl Isononanoate, as described in WO2012/120043.

(87) The flow rates considered (in mL/h) are as follows:

(88) TABLE-US-00023 OF (=emulsion (E1) 150 FI (optional) 2 IF2 20

(89) The manufacture of the drops (G2) is therefore simultaneous with the manufacture of the composition according to the invention. At the end of the manufacture of this composition, a base solution (BFI), identical to that described in Example 2, may be added, preferably microfluidically, so as to enhance the viscosity of the aqueous phase in the composition according to the invention, and thus suspend the drops (G2).

Example 5: Example of a Cosmetic Composition

(90) A composition as described in the table below may be prepared according to one of the manufacturing methods described in the present invention and, in particular, according to the method described in Example 3 above.

(91) TABLE-US-00024 % w/w Name INCI name final AQUEOU PHASE GEL Osmosis water Water qsp Microcare PE Phenoxyethanol 0.1-1% Microcare PTG Pentylenglycol 0.5-4% Tego Carbomer Carbomer 0.01-1% 340 FD Carbopol Ultrez Acrylates/C10-30 0.1-2% 21 Polymer Alkyl Acrylate Crosspolymer Glycerine codex Glycerin 1-15% (99%) EDETA BD Disodium EDTA 0.01-0.5% Denatured ethyl Ethanol .sup.1-6% alcohol BITREX/ TBA Sodium Hydroxide Sodium Hydroxide 0.001-0.1% Pellets PRS codex OIL PHASE of the drops (G1) DUB ININ Isononyl Isononanoate 1-10% Isostearyl Neopentanoate 0.5-5% Isodecyl neopentanoate 0.5-5% Isododecane 0.5-5% PLANTEC REFINED Butyrospermum Parkii 0.5-5% SHEA BUTTER Squalane 0.1-5% CREASPERSE CI 77510 (and) .sup.0-1% IRON BLUE Hydrogenated Polydecene (and) Hydroxystearic Acid Perfume Perfume 0.1-1% CAS-3131 Amodimethicone 0.01-0.5%.sup. OIL PHASE of the drops (G2) DUB ININ Isononyl Isononanoate 0.1-5% Isostearyl Neopentanoate 0.5-5% Octyldodecyl myristate 0.5-5% Neopentyl glycol 0.5-5% diheptanoate and isododecane Rheopearl KL2 Dextrin Palmitate 0.5-5% CREASPERSE CI 77510 (and) .sup.0-1% IRON BLUE Hydrogenated Polydecene (and) Hydroxystearic Acid CAS-3131 Amodimethicone 0.01-0.5% TOTAL 100.00

(92) A composition according to Example 5 may be applied every morning on the face to moisturize, strengthen the barrier function, protect and bring radiance to the skin.

(93) It has been observed that a composition according to Example 5, in use, especially as indicated above, allows prolonged microdiffusion of the active ingredients, in particular moisturizing and anti-aging agents, and in fact provides a continuous action in the heart of the skin.