Dry powder inhaler

Abstract

A novel dry powder inhaler. By providing a plurality of capsule chambers (1a, 1b, 1c, 1d) arranged in parallel in a capsule dry powder inhalation device, a medicine dispenser containing active components of a composite product or their mixture separately is provided. The dry powder inhaler has a simple structure and is convenient to operate. In addition, the parameters of air inlet channels and an air outlet channel can be adjusted by means of each capsule chamber (1a, 1b, 1c, 1d) according to the properties of powder of a medicine or a combination, so as to provide an appropriate particle distribution for each active component.

Claims

1. Dry powder inhaler, comprising: capsule chambers (1), which are cylindrical chambers for holding capsules upright, tops of the capsule chambers (1) are open, and bottoms of the capsule chambers (1) are provided with intake ducts ventilating with outside air; actuators (2), comprising puncture needles (21), mounted for a user to operate to move toward a side wall of each of the capsule chambers (1) to puncture the capsules; nozzle (3), comprising an outlet duct (11) under the nozzle (3); wherein, a number of the capsule chambers (1) is two, and all the capsule chambers (1) are arranged in parallel to form an integral multi-capsule chamber, the actuators (2) are mounted individually or in common among the capsule chambers (1), and the actuators (2) are mounted with needles (21) in a width direction of the actuators (2), a screen cover (15) is mounted at a bottom of the outlet duct (11) under the nozzle (3), and a screen (12) is fixed in the screen cover (15) and separately connected to the top of the multi-capsule chamber, making the screen (12) cover the tops of all of the capsule chambers (1), wherein each capsule chamber (1) is provided at the side wall of the capsule chamber (1) with at least one deflected intake duct group, the deflected intake duct group comprises at least two deflected intake ducts (13) which are arranged around a central axis of the capsule chamber (1), and simultaneously deflect clockwise or counterclockwise, wherein a lower part of the outlet duct (11) is divided by a central baffle (111) to form two sub-ducts, which are respectively connected to the top of each capsule chamber (1), each cross-section of each respective sub-duct gradually narrowing from the tops of the capsule chambers towards an upper part of the outlet duct, wherein each cross-section stops narrowing and then remains a same size until the sub-ducts converge together into one duct at the upper part of the outlet duct, wherein the central baffle extends from the tops of the capsule chambers towards the nozzle at least to a point where the sub-ducts stop narrowing, wherein each sub-duct comprises one or more sub-baffles, the sub-baffles divide the sub-duct into narrower ducts, wherein the narrower ducts converge into a respective sub-duct above the sub-baffles.

2. The dry powder inhaler of claim 1, wherein the at least two deflected intake ducts (13) of the deflected intake duct group of each capsule chamber (1) have a same shape and size, and are evenly arranged around the central axis of the capsule chamber (1).

3. The dry powder inhaler of claim 2, wherein the at least two deflected intake ducts (13) of each capsule chamber (1) are tangent to the side wall of their respective capsule chambers (1).

4. The dry powder inhaler of claim 1, wherein an opening of each of the at least two deflected intake ducts (13) on the side wall of each capsule chamber (1) has a long-strip shape, which is arranged longitudinally along the side wall.

5. The dry powder inhaler of claim 1, wherein a size of the intake duct and/or top opening of at least one of the capsule chambers (1) is different from others of the capsule chambers (1).

6. The dry powder inhaler of claim 1, wherein the cross-section of the outlet duct (11) gradually increases in a direction from a top of the central baffle (111) toward the nozzle (3).

7. The dry powder inhaler of claim 6, wherein the cross-section of the outlet duct (11) gradually increases, and then remains the same size.

8. The dry powder inhaler of claim 1, wherein a height of the sub-baffles (112) is lower than a height of the central baffle (111).

9. The dry powder inhaler of claim 1, wherein the cross-section of each sub-baffle (112) is arranged radially with the center baffle (111) as a center.

10. The dry powder inhaler of claim 9, wherein a shape of the cross-section of each sub-baffle (112) is X-shaped, which takes the central baffle (111) as a plane mirror symmetry.

11. The dry powder inhaler of claim 10, wherein an air resistance of the dry powder inhaler is 0.0325 KPa.sup.0.5 minutes/liter.

12. The dry powder inhaler of claim 10, wherein a length of the outlet duct (11) is 25-36 mm.

13. The dry powder inhaler of claim 1, wherein the multi-capsule chamber is composed of a first capsule chamber (1a) and a second capsule chamber (1b) which are closely arranged, and the actuators (2) comprise a first actuator (2a) and a second actuator (2b), which are arranged at both ends of a connecting line where the first capsule chamber (1a) and the second capsule chamber (1b) are located, the first actuator (2a) is movable from both sides of the first capsule chamber (1a) to a middle of the first capsule chamber (1a), and the second actuator (2b) is movable from both sides of the second capsule chamber (1b) to a middle of the second capsule chamber (1b), so as to puncture the capsules in the first capsule chamber (1a) and the second capsule chamber (1b), respectively.

14. The dry powder inhaler of claim 1, further comprising a lower casing, which defines a cavity, the top of which is open and is used for accommodating the multi-capsule chamber inside, the side of the lower casing is provided with gaps that match a number and positions of the actuators, so that part of each actuator is located outside the dry powder inhaler, and the cavity ventilates with outside air.

15. The dry powder inhaler of claim 14, further comprising an adapter plate, which covers the top of the lower casing, and a hollow port is provided at the top of the multi-capsule chamber, the screen cover is detachably mounted to the hollow port so that the screen covers the top of each capsule chamber through the hollow port.

16. The dry powder inhaler of claim 15, further comprising an upper casing, which extends downward from a top of the nozzle, defines a cavity surrounding the outlet duct and the bottom of the cavity being open, and covers the adapter plate when the screen cover is mounted at the hollow port.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

(1) FIG. 1 shows a disassembled view of the structure of a powder release device of this invention.

(2) FIG. 2 shows a sectional view of a capsule chamber of the powder release device shown in FIG. 1

(3) FIG. 3 shows a cross-sectional top view of the capsule chamber shown in FIG. 2.

(4) FIG. 4 shows another sectional view of the capsule chamber of the powder release device shown in FIG. 1.

(5) FIG. 5 shows a structural view of the lower part of the section of the capsule chamber shown in FIG. 4.

(6) FIG. 6 shows another sectional view of the capsule chamber of the powder release device shown in FIG. 1.

(7) FIG. 7 shows a sectional top view of the capsule chamber shown in FIG. 6.

(8) FIG. 8 shows another sectional view of the capsule chamber area of the powder release device shown in FIG. 1.

(9) FIG. 9 shows a sectional top view of the capsule chamber shown in FIG. 8.

(10) FIG. 10 is a partially enlarged view of the impeller at the bottom of the capsule chamber shown in FIG. 9.

(11) FIG. 11 is a sectional view of another capsule chamber area of the powder release device shown in FIG. 1.

(12) FIG. 12 shows a sectional top view of the capsule chamber area shown in FIG. 11.

(13) FIG. 13 shows a disassembled view of the structure of a dry powder inhaler of the present invention.

(14) FIG. 14 is a partial cross-sectional view of the dry powder inhaler shown in FIG. 13.

(15) FIG. 15 is a perspective view of the nozzle of the dry powder inhaler shown in FIG. 13.

(16) FIG. 16 is a perspective view of the screen cover of the dry powder inhaler shown in FIG. 13.

(17) FIG. 17 shows a sectional plan view of the multi-capsule chamber of the dry powder inhaler shown in FIG. 13.

(18) FIG. 18 shows a sectional top view of a multi-capsule chamber of another dry powder inhaler of the present invention.

(19) FIG. 19 shows a sectional top view of a multi-capsule chamber of another dry powder inhaler of the present invention.

(20) FIG. 20 is a partial sectional view of another dry powder inhaler of the present invention.

(21) FIG. 21 is a sectional view of the airflow of the nozzle of the dry powder inhaler shown in FIG. 20.

(22) FIG. 22 is a plan view of the nozzle of the dry powder inhaler shown in FIG. 20.

DETAILED DESCRIPTION OF THE EMBODIMENTS

(23) The present invention will be further described below in conjunction with specific embodiments. However, it should not be understood that the scope of the above subject of this application is only limited to the following embodiments, and any technology implemented based on the content of this application belongs to the scope of this application.

(24) By referring to FIG. 1, FIG. 2 and FIG. 3, FIG. 1 illustrates a specific embodiment of a powder release device of the present invention, comprising: (a) a capsule chamber 1, which is a cylindrical chamber that can receive the capsule, the capsules chamber 1 is provided with an outlet duct 11 at the top thereof, and a ventilating screen 12 is mounted at the junction of the outlet duct 11 and the capsule chamber 1; (b) the actuator 2, which comprises at least one needle 21, which is mounted as it can move to the capsule chamber 1 to puncture the capsule, and at least one part of the actuator 2 is located outside the powder release device for the user to manipulate; (c) the nozzle 3, which is connected to the top of the capsule chamber 1 through the outlet duct 11. By referring to FIG. 2, the capsule chamber 1 is provided with a deflected intake duct group that ventilates with outside air. By referring to, the deflected intake duct group comprises at least two deflected intake ducts 13, which are arranged around the central axis of the capsule chamber and simultaneously deflect clockwise or counterclockwise, in order to provide a spiral airflow that flows from the deflected intake duct group to the top outlet duct 11 when the user inhales.

(25) In this embodiment, the user opens the screen 12 mounted above the capsule chamber 1 first and puts the capsule herein, then presses the actuator 2 to puncture the capsule, and the actuator 2 is then reset by manual operations or elastic means. Since the nozzle 3 ventilates with the capsule chamber 1 through an outlet duct 11, and the capsule chamber 1 ventilates with the external environment through the deflected intake duct group, when the user inhales, the outside air passes through the deflected intake duct group to generate a spiral airflow surrounding the capsule chamber 1, to promote a rapid rotation of the punctured capsule to release the inhalable medicinal powder contained therein. The inhalable medicinal powder moves with the airflow to the outlet duct 11 at the top of the capsule chamber 1 and enters the user's body through the nozzle 3.

(26) It should be noted that the deflected intake duct 13 of this embodiment is deflected clockwise or counterclockwise, but it does not mean that the deflected intake duct group must be opened in the horizontal direction, as long as it can provide a part of the air flow deflected in the horizontal direction. Of course, the at least two deflected intake ducts 13 should be deflected simultaneously. For example, when the deflected intake passages 13 are located on the side wall, they should all face diagonally upward, all face diagonally downward, or all face horizontally.

(27) Compared with the prior art, the powder release device of this embodiment provides the deflected intake duct group in the capsule chamber 1, so that the requirement of the user's inhalation flow when the capsule rotates and releases medicine is greatly reduced, the powder is easier to release and the amount of residue reduces.

(28) The deflected intake ducts 13 of the deflected intake duct group have the same shape and size, and are evenly arranged around the central axis of the capsule chamber 1 to provide more uniform spiral airflow. Since the release of the inhalable powder in the capsule is achieved by the rotation and vibration of the capsule in the capsule chamber 1, but not based on only the rotation, the shapes and sizes of the deflected intake ducts 13 of the deflected intake duct group do not have to be exactly the same.

(29) Compared with the prior art, the powder release device of this embodiment provides the deflected intake duct group in the capsule chamber 1, so that the requirement of the user's inhalation flow rate when the capsule rotates and vibrates to release medicine is greatly reduced, the powder is easier to release and the amount of residue is reduced.

(30) Further preferably, by referring to FIG. 1, in one embodiment, the lower side of the ventilating screen 12 protrudes toward the capsule chamber 1, and this shape can provide a capsule rotating contact surface with less resistance.

(31) Further preferably, by referring to FIG. 2 and FIG. 3, in one embodiment, the deflected intake duct group is provided on the side wall of the capsule chamber 1, and the bottom of the capsule chamber 1 is also provided with an intake duct 14 ventilating with the outside air, which is opened upwards along the central axis of the capsule chamber 1 to provide an air flow throughout the capsule chamber 1 from bottom to top when the user inhales.

(32) In this embodiment, the intake duct 14 at the bottom of the capsule chamber 1 can provide a through airflow throughout the entire capsule chamber 1 from bottom to top when the user inhales, in order to help the top of the capsule to rotate against the ventilating screen 12 at the top of the capsule chamber 1, so that the powder released from the capsules moves toward the top of the outlet duct 11 more smoothly.

(33) In this embodiment, the opening of the deflected intake duct 13 at the side wall of the capsule chamber 1 has a long-strip shape, which is arranged longitudinally along the side wall of the capsule chamber, in order to provide an airflow having a larger surface contact with the capsule when the user inhales, so as to drive the capsule to rotate and vibrate easier in the capsule chamber 1 to release the inhalable powder.

(34) Further preferably, by referring to FIG. 2 and FIG. 3, in one embodiment, the opening of the deflected intake duct 13 at the side wall of the capsule chamber 1 has a long-strip shape which is parallel to the central axis of the capsule chamber, so that when the user inhales, an airflow with a larger surface contact with the capsule and a better applying force direction is provided to drive the capsule to rotate and vibrate more smoothly in the capsule chamber 1 so as to release the inhalable powder.

(35) Further preferably, by referring to FIG. 4 and FIG. 5, in one embodiment, the deflected intake duct group is provided at the lower part of the side wall of the capsule chamber 1, and the intake duct 14 is provided at the bottom of the capsule chamber 1, wherein the intake duct is opened upwards along the central axis of the capsule chamber 1 to provide an air flow throughout the capsule chamber 1 from bottom to top when the user inhales.

(36) The deflected intake duct group is provided at the lower part of the side wall of the capsule chamber 1, which can better provide a through airflow throughout the entire capsule chamber 1 from bottom to top when the user inhales, in order to help the top of the capsule to rotate against the ventilating screen 12 at the top of the capsule chamber 1, so that the powder released from the capsule moves toward the top of the outlet duct 11 more smoothly.

(37) Further preferably, by referring to FIG. 6 and FIG. 7, in one embodiment, the deflected intake duct group is provided at the lower part of the side wall of the capsule chamber 1, and the intake duct 14 is not provided at the bottom of the capsule chamber 1.

(38) The deflected intake duct group is only provided at the lower part of the side wall of the capsule chamber 1, which can also provide a bottom-up airflow when the user inhales, in order to help the top of the capsule to rotate against the ventilating screen 12 at the top of the capsule chamber 1. It can be understood that, in order to make the top of the capsule rotate against the screen 12 at the top of the capsule chamber 1, the through airflow is not necessary, as long as a non-through airflow from bottom to top is enough to lift the capsule.

(39) By referring to FIG. 8, FIG. 9 and FIG. 10, in another embodiment of a powder release device of the present invention, a deflected intake duct group is provided at the bottom of the capsule chamber 1.

(40) In this embodiment, the deflected intake duct group at the bottom of the capsule chamber 1 can also be evenly arranged around the central axis of the capsule chamber, simultaneously deflect clockwise or counterclockwise. When the user inhales, it can provide a part of the spiral airflow that is deflected in the horizontal direction to help the capsule rotate and vibrate to release the inhalable powder, and it can also provide another part of the bottom-to-up through airflow to help the top of the capsule rotate against the ventilating screen 12 at the top of the capsule chamber 1, so that the powder released from the capsule moves towards the top of the outlet duct 11 more smoothly. The structure is simple, and it serves two purposes.

(41) Further preferably, by referring to FIG. 9 and FIG. 10, in one embodiment, the deflected intake duct group at the bottom is arranged as a fixed impeller as a whole.

(42) In this embodiment, the deflected intake duct group of the impeller structure at the bottom of the capsule chamber 1 can be understood as being composed of four deflected intake ducts 13 separated by four blades.

(43) Further preferably, by referring to FIG. 11 and FIG. 12, in one embodiment, each of the bottom and side walls of the capsule chamber 1 is provided with a deflected intake passage group.

(44) In this embodiment, each of the deflected intake duct groups at the bottom of the capsule chamber 1 and those at the side wall serve to provide deflected airflow, wherein the deflected intake duct groups at the bottom of the capsule chamber 1 can also provide a bottom-up through airflow, and the object of the present invention can also be achieved.

(45) By referring to FIG. 13 and FIG. 14, it is an embodiment of a dry powder inhaler of the present invention, comprising: (a) capsule chambers 1 (that is, 1a and 1b in the FIG.), which are cylindrical chambers that can hold a capsule upright, the top of the capsule chambers 1 is open, and the bottom of the capsule chambers 1 is provided with intake ducts 14 that ventilate with the outside air; (b) actuators 2, which comprise puncture needles 21, the puncture needles 21 are mounted for the user to operate to move toward the side walls of the capsule chambers 1 to puncture the capsules; (c) nozzle 3, illustrated in FIG. 13 and FIG. 15, which comprises an outlet duct 11 below the nozzle (for clarity, the lower part of the outlet 11 in FIG. 13 is intercepted and separated for display); wherein, the number of the capsule chambers 1 is two, the two capsule chambers 1 are arranged in parallel to form an integrally formed double-capsule chamber, and the actuators 2 are mounted individually between the capsule chambers 1, each actuator 2 is provided with two needles 21 in the height direction, a screen cover 15 is mounted at the bottom opening of the outlet duct 11, by referring to FIG. 16, a screen 12 is mounted in the screen cover 15 and can be separately connected to the top of the double-capsule chamber, so that the screen 12 covers the tops of the two capsule chambers 1.

(46) In this embodiment, the double capsule-chamber is composed of first capsule chamber 1a and second capsule chamber 1b which are closely arranged, and the first actuator 2a and the second actuator 2b are arranged at both ends of the line where the first capsule chamber 1a and the second capsule chamber 1b are located, the first actuator 2a and the second actuator 2b can move from both sides to the middle so as to puncture the capsules in the first capsule chamber 1a and the second capsule chamber 1b, respectively.

(47) The user separates the screen cover 15 from the top of the double-capsule chamber first, to make the top of the double-capsule chamber open; after filling the capsule chambers 1 with capsules containing different active ingredients, the screen cover 15 is closed to make the screen 12 cover the top of the capsule chambers 1 again; then, the user operates the actuators 2 to move from both sides to the middle so as to puncture the capsules in the first capsule chamber 1a and the second capsule chamber 1b, respectively, and the actuators 2 are reset by elastic components commonly used in the prior art; finally, the user covers the mouth to the nozzle 3 closely and inhales forcefully, and the outside air enters the capsule chambers through the intake duct 14 at the bottom of the capsule chambers 1, so that the capsules vibrate and rotate against the screen 12 to release the powder. The released powder from the capsules passes through the screen 12 into the outlet duct 11 and finally enters the human body.

(48) Although the actuators 2 of this embodiment move from both sides to the middle so as to puncture the capsules in the first capsule chamber 1a and the second capsule chamber 1b, respectively, person skilled in the art can adjust the arrangement of the actuators, for example, the actuators 2 are provided on one side of the line where the first capsule chamber 1a and the second capsule chamber 1b are located, the actuators 2 comprise at least two needles in the width direction, so that when operated, the actuators 2 puncture the capsules in the first capsule chamber 1a and the second capsule chamber 1b at the same time.

(49) Further preferably, by referring to FIG. 17, in one embodiment, the side wall of each capsule chamber 1 is respectively provided with a deflected intake duct group. The deflected intake duct group comprises two deflected intake ducts 13 which are arranged around the central axis of the capsule chamber 1, simultaneously deflect clockwise or counterclockwise, in order to provide a spiral airflow that flows upward from the deflected intake ducts 13 when the user inhales.

(50) Compared with the foregoing embodiment, the inhaler of this embodiment is provided with a deflected intake duct group on the side wall of the capsule chamber 1 to provide a spiral airflow that moves upward from the deflected intake duct 13 when the user inhales. The airflow can help the capsules rotate and vibrate more smoothly to release the inhalable powder, which greatly reduces the requirement of the user's inhalation flow when the capsules rotate and release medicine, and can release the powder easier.

(51) Further preferably, by referring to FIG. 13 and FIG. 14, in one embodiment, the deflected intake duct group is provided at the lower part of the side wall of each capsule chamber 1.

(52) Compared with the previous embodiment, the inhaler of this embodiment provides a deflected intake duct group at the lower part of the capsule chamber 1, which can not only provide a spiral airflow moving upward from the deflected intake duct 13, but also assist the bottom of the intake duct 14 to make the top of the capsule rotate against the screen 12 at the top of the capsule chambers.

(53) Further preferably, by referring to FIG. 17, in one embodiment, the direction of the deflected intake ducts 13 is tangent to the side wall of each capsule chamber 1, so that the spiral airflow can smoothly drive the capsules to rotate.

(54) Further preferably, by referring to FIG. 20, in one embodiment, the lower part of the outlet duct 11 is divided by a central baffle 111 to form a first sub-duct 11a and a second sub-duct 11b, which are respectively connected to the tops of the first capsule chamber and the second capsule chamber, the first sub-duct 11a and the second sub-duct 11b gradually gather from the bottom to top toward the central baffle 111, the cross-sections thereof are gradually narrowed first and then remain unchanged, so that when the user inhales, the airflows in the first capsule chamber 1a and the second capsule chamber 1b are directed along the first sub-duct 11a and the second sub-duct 11b to merge in the upper part of the outlet duct 11 respectively.

(55) By referring to FIG. 21, through the special design of the lower part of the outlet duct 11 of this embodiment, when the user inhales, the airflows in the two capsule chambers can be gathered in the area above the central baffle 111 and converged, and then be directed to flow above the outlet duct, so not only can the drug powder released in the two capsule chambers be fully mixed, but also can the collision with the duct be reduced, thereby the resistance when user inhales can be reduced.

(56) More preferably, by referring to FIG. 20 and FIG. 21, in one embodiment, the cross-section of the outlet duct 11 gradually increases from the top of the central baffle 111 toward the nozzle 3 and then remains unchanged. when the user inhales, the airflows in the two capsule chambers(1a, 1b) can be gathered in the area above the central baffle 111 and converged, and then be directed to flow above the outlet duct, therefore, the cross-section of the outlet duct 11 of the present embodiment gradually increases from the top of the central baffle 111 toward the nozzle 3 and then remains unchanged, which is advantageous for air to flow upwards more smoothly, as the obstruction of the of the inner wall of the airflow duct 11 to the airflow is reduced and the collision of the drug powder in the airflow with the inner wall of the outlet duct 11 is reduced. It can be understood that, in order to achieve the above effect, the cross-section of the outlet duct 11 from the top of the central baffle 111 toward the nozzle 3 does not necessarily gradually increase and then remains unchanged, as long as it does not decrease.

(57) More preferably, by referring to FIG. 22, in one embodiment, the first sub-duct 11a and the second sub-duct 11b further comprise two sub-baffles 112, and the first sub-duct 11a and the second sub-duct 11b are further divided by the sub-baffles 112 into a plurality of narrow ducts that gradually gather from the top of each capsule chamber from bottom to top toward the central baffle 111 respectively, the height of the sub-baffle 112 is lower than that of the central baffle 111. The cross-section of the sub-baffles is X-shaped, which is mirror-symmetrical with the central baffle 111 as the symmetry plane.

(58) In this embodiment, the sub-ducts (11a, 11b) are further divided into six narrow ducts, each narrow duct can guide the direction of the gathered airflow more precisely according to its position, so as to make the airflows from the two capsule chambers (1a, 1b) gather more smoothly and converge on the upper area of the central baffle 111, and then be directed to flow above the outlet duct.

(59) More preferably, by referring to FIG. 20, in one embodiment, the airflows from the first capsule chamber 1a and the second capsule chamber 1b flows along the first sub-channel 11a and the second sub-channel 11b to the upper part of the outlet duct 11 respectively when the user inhales, and the nozzle 3 is provided at a position where the airflows are sufficiently converged, and the height of the outlet duct 11 is 31 mm.

(60) The height of the outlet duct 11 in this embodiment refers to the distance from the top of the capsule chamber to the nozzle 3, as shown in FIG. 21, in the vicinity of the nozzle at the end of the outlet duct, the airflow in the two capsule chambers (1a, 1b) has been fully converged, and the drug powder in the airflow is also fully mixed. Further increasing the distance of the outlet duct will increase the inhalation resistance.

(61) Further preferably, by referring to FIG. 13, FIG. 14 and FIG. 15, in one embodiment, the dry powder inhaler further comprises: (d) the lower casing 4, which defines a cavity, the tope of which is open and is used for accommodating the double-capsule chamber, and the lower casing 4 is provided with two gaps 41 on the side thereof, so that at least one part of the each actuator 2 is provided located outside of the dry powder inhaler for user to operate, the gaps 41 extend downward and widen with respect to the size of the actuators 2 to provide an air intake 42, so that the inside of the cavity can ventilate with the outside air through the air intake 42; (e) the adapter plate 5 which covers the top of the lower casing 4, and a hollow port 51 is provided at the top of the multi-capsule chamber, and a screen cover 15 is detachably mounted to the hollow port 51 so that the screen 12 covers the top of each capsule chamber 1; (f) the upper casing 6, which extends downward from the top of the nozzle 3, defines a cavity that is open at the bottom and surrounds the outlet duct 11, and covers the adapter plate 5 when the screen cover 15 is mounted at the hollow port.

(62) First, the user separates the lower casing 4 and the upper casing 6 so as to separate the screen cover 15 from the top of the double-capsule chamber, then fills each capsule chambers 1 with capsules containing two different active ingredients, and then closes the upper casing 6 and the lower casing 4 so that the screen 12 covers the top of the capsule chambers 1 again; then, the user operates parts of the actuators 2 located out of the casings to puncture the capsules in the capsule chambers 1, the actuators 2 are reset by the elastic components commonly used in the prior art; finally, the user closely fits the mouth to the nozzle 3 and inhales in force, the outside air enters the cavity through the air intake hole 42 of the lower casing 4, and enters the capsule chambers 1 from the intake ducts 14 at the bottom of the capsule chambers 1, so that the capsules vibrate and rotate against the screen 12 to release the powder. The released powder from the capsule enters the outlet duct 11 through the screen 12 and finally enters the human body.

(63) Compared with the previous embodiment, the dry powder inhaler of this embodiment adds the upper casing 6, the lower casing 4 and the adapter plate 5 on the premise of supporting the technical solution of the previous embodiment, thereby increasing the structural firmness of the dry powder inhaler, and making it easy to operate. The upper casing 6, the lower casing 4 and the adapter plate 5 are all conventional components of the same type of dry powder inhaler in the prior art. In this embodiment, the upper casing 6, the lower casing 4 and the adapter plate 5 are also conventional designs in the prior art.

(64) Further preferably, by referring to FIG. 13, FIG. 14 and FIG. 15, in one embodiment, a slit 52 is provided at the junction of the upper casing 6 and the adapter plate 5, so that the internal cavity can ventilate with the outside air through the slit 52. The side wall of the outlet duct 11 is provided with a small hole 113, which is opened in a direction not facing the central axis of the outlet duct 11 to promote airflow rotate in the outlet duct 11 when the user inhales.

(65) When the user inhales, external air can enter the internal cavity of the upper casing 6 through the slit and enter the outlet duct 11 from the small hole 113 of the outlet duct 11 to promote the rotation of the airflow in the outlet duct 11, in this embodiment, after the capsule medicine powder in each capsule chamber 1 is released, it is transmitted in the outlet duct 11 and fully mixed by rotation, so that the moving speed of the airflow arriving at the nozzle 3 is proper and the ingredients are uniform.

(66) Further preferably, by referring to FIG. 14, in one embodiment, the diameter of the outlet duct 11 gradually decreases from bottom to top, and a narrow neck 114 is formed before reaching the outlet, so that the moving speed of the airflow arriving at the nozzle 3 is proper and the ingredients are uniform.

(67) By referring to FIG. 18, it is another embodiment of the dry powder inhaler of the present invention. The multi-capsule chamber is composed of a first capsule chamber 1a, a second capsule chamber 1b, and a third capsule chamber 1c, which are closely arranged into a triangle. The first actuator 2a is arranged on one side of a line where the first capsule chamber 1a and the second capsule chamber 1b are connected, and the first actuator 2a is provided with two needles 21 in the width direction, and the two needles can move to the multi-capsule chamber to puncture the capsules in the first capsule chamber 1a and the second capsule chamber 1b at the same time, and the second actuator 2b is arranged on a side of the third capsule chamber 1c away from the first capsule chamber 1a and the second capsule chamber 1b, and is movable in a direction perpendicular to the straight line where the first capsule chamber 1a and the second capsule chamber 1b lie to puncture the capsule in the third capsule chamber 1c.

(68) This embodiment provides a medicine dispenser containing three active components (or a mixture thereof) in a separated manner by providing three capsule chambers, and an intake duct 14 is provided at the bottom of each capsule chamber 1, and no deflected intake duct group is provided on the side or bottom of each capsule chamber. The arrangement of other components is the same as or similar to that in other embodiments, and details are not described herein again.

(69) Further preferably, by referring to FIG. 18, in one embodiment, the diameter of the bottom intake duct 14 of one capsule chamber 1 is different from that of the other two capsule chambers, so that the intake airflow rate of the capsule chamber is different from that of the other capsule chambers.

(70) In some cases, each component of the combined product needs to achieve a specific particle distribution to maximize its effect. Since each component of the present invention is released separately in each corresponding capsule chamber 1, by adjusting structural characteristics such as the size, position, opening angle, and/or the number of the intake ducts 13, the intake ducts 14, and/or the air outlet duct 11, different aerodynamic parameters can be set for each capsule chamber 1, in order to maximize the therapeutic effect of each active ingredient under the premise of simultaneous administration. In this embodiment, the size of the intake duct 14 at the bottom of the capsule chambers 1 is adjusted to give different air flow rates to affect the particle distribution of the powder in the capsules.

(71) By referring to FIG. 19, it is another embodiment of the dry powder inhaler of the present invention, the multi-capsule chamber 1 is composed of the first capsule chamber 1a, the second capsule chamber 1b, the third capsule chamber 1c and the fourth capsule chamber 1d, which are arranged closely as a square. The first actuator 2a and the second actuator 2b are arranged on the central axis of the square and can move from both sides to the middle, the first actuator 2a and the second actuator 2b comprises at least two needles 21 in the width direction so that the first actuator 2a simultaneously punctures the capsules in the first capsule chamber 1a and the second capsule chamber 1b, and the second actuator 2b simultaneously punctures the capsules in the third capsule chamber 1c and the fourth capsule chamber 1d.

(72) This embodiment provides a medicine dispenser containing four active components (or a mixture thereof) in a separated manner by providing four capsule chambers. Providing four capsule chambers results in a higher requirement for the inhaler for the patient's inspiratory flow. In order to rotate and vibrate the capsule fully to release the inhalable powder, each capsule chamber 1 of this embodiment is provided with a deflected intake duct group at the bottom of the capsule chamber, and the intake duct group is arranged as a fixed impeller to provide a spiral air flow from bottom to top when the user inhales, which effectively promotes the capsule's rotation and vibration to release the inhalable powder. The specific shape of the impeller structure is shown in FIG. 10.

(73) The above are only the specific embodiments of the present invention and are not intended to limit the scope of the present invention. Any equivalent change, modification and combination made by persons skilled in the art without departing from the concept and principle of the present invention shall fall within the protection of this application.