2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS

Abstract

The invention relates to novel compounds of the formula (I)

##STR00001##

in which A.sup.1, A.sup.2, A.sup.3, X, Y, V, R.sup.1, R.sup.2, R.sup.3, R.sup.5, R.sup.6 and n have the meanings mentioned above,
to the use thereof as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for preparation thereof.

Claims

1. A compound of formula (I) ##STR00068## in which A.sup.1 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4a)—, A.sup.2 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4b)—, A.sup.3 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4c)—, X represents oxygen or sulfur, Y represents oxygen or sulfur, R.sup.1 represents (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.3-C.sub.8)-cycloalkyl, halo-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.1-C.sub.6)-alkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.1-C.sub.6)-haloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-haloalkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.8)-cycloalkyl-(C.sub.3-C.sub.8)-cycloalkyl, spiro-(C.sub.3-C.sub.8)-cycloalkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.4-C.sub.12)-bicycloalkyl, (C.sub.1-C.sub.6)-cyanoalkyl, (C.sub.1-C.sub.6)-hydroxyalkyl, (C.sub.1-C.sub.6)-alkoxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.2-C.sub.6)-cyanoalkenyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-cyanoalkynyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.2-C.sub.6)-alkynyl, (C.sub.1-C.sub.6)-haloalkoxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.2-C.sub.6)-alkenyloxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.2-C.sub.6)-haloalkenyloxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.2-C.sub.6)-alkynyloxy-(C.sub.1-C.sub.4)-alkyl, (C.sub.2-C.sub.6)-haloalkynyloxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-alkylthio-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-alkylsulfinyl-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-alkylsulfonyl-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkylthio-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl-(C.sub.1-C.sub.6)-alkyl or tri-(C.sub.1-C.sub.6)-alkylsilyl, R.sup.2, R.sup.4a, R.sup.4b, R.sup.4c independently of one another represent hydrogen, cyano, halogen, (C.sub.1-C.sub.4)-alkyl, (C.sub.1-C.sub.4)-haloalkyl, (C.sub.1-C.sub.4)-cyanoalkyl, (C.sub.1-C.sub.4)-alkoxy-(C.sub.1-C.sub.4)-alkyl, (C.sub.2-C.sub.4)-alkenyl, (C.sub.2-C.sub.4)-haloalkenyl, (C.sub.2-C.sub.4)-cyanoalkenyl, (C.sub.2-C.sub.4)-alkynyl, (C.sub.2-C.sub.4)-haloalkynyl, (C.sub.2-C.sub.4)-cyanoalkynyl, (C.sub.1-C.sub.4)-alkoxy, (C.sub.1-C.sub.4)-haloalkoxy, (C.sub.1-C.sub.4)-alkylthio, (C.sub.1-C.sub.4)-haloalkylthio, (C.sub.1-C.sub.4)-alkylsulfinyl, (C.sub.1-C.sub.4)-haloalkylsulfinyl, (C.sub.1-C.sub.4)-alkylsulfonyl or (C.sub.1-C.sub.4)-haloalkylsulfonyl, R.sup.3 represents hydrogen, cyano, halogen, nitro, hydroxy, amino, SCN, tri-(C.sub.1-C.sub.6)-alkylsilyl, (C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.8)-cycloalkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.8)-cycloalkyl, halo-(C.sub.3-C.sub.8)-cycloalkyl, cyano-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.1-C.sub.6)-cyanoalkyl, (C.sub.1-C.sub.6)-hydroxyalkyl, (C.sub.1-C.sub.6)-alkoxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-cyanoalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.2-C.sub.6)-cyanoalkynyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-cyanoalkoxy, (C.sub.1-C.sub.6)-alkylhydroxyimino, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkyl-(C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-haloalkyl-(C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl, (C.sub.1-C.sub.6)-alkylcarbonyl, (C.sub.1-C.sub.6)-alkylthiocarbonyl, (C.sub.1-C.sub.6)-haloalkylcarbonyl, (C.sub.1-C.sub.6)-alkylcarbonyloxy, (C.sub.1-C.sub.6)-alkoxycarbonyl, (C.sub.1-C.sub.6)-haloalkoxycarbonyl, aminocarbonyl, (C.sub.1-C.sub.6)-alkylaminocarbonyl, (C.sub.1-C.sub.6)-alkylaminothiocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminothiocarbonyl, (C.sub.3-C.sub.8)-cycloalkylaminocarbonyl, (C.sub.1-C.sub.6)-alkylsulfonylamino, (C.sub.1-C.sub.6)-alkylamino, di-(C.sub.1-C.sub.6)-alkylamino, aminosulfonyl, (C.sub.1-C.sub.6)-alkylaminosulfonyl, di-(C.sub.1-C.sub.6)-alkylaminosulfonyl, (C.sub.1-C.sub.6)-alkylsulfoximino, aminothiocarbonyl, (C.sub.1-C.sub.6)-alkylaminothiocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminothiocarbonyl, (C.sub.3-C.sub.8)-cycloalkylamino or NHCO—(C.sub.1-C.sub.6)-alkyl ((C.sub.1-C.sub.6)-alkylcarbonylamino), R.sup.5, R.sup.6 independently of one another represent hydrogen, cyano, halogen, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.3-C.sub.6)-cycloalkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl, (C.sub.1-C.sub.6)-alkylsulfonyloxy, (C.sub.1-C.sub.6)-alkylcarbonyl, (C.sub.1-C.sub.6)-haloalkylcarbonyl, aminocarbonyl, (C.sub.1-C.sub.6)-alkylaminocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminocarbonyl, (C.sub.1-C.sub.6)-alkylsulfonylamino, aminosulfonyl, (C.sub.1-C.sub.6)-alkylaminosulfonyl or di-(C.sub.1-C.sub.6)-alkylaminosulfonyl, n represents 0, 1 or 2, V represents a saturated, partially saturated or heteroaromatic ring which is optionally mono- or polysubstituted by identical or different substituents, and in which at least one carbon atom is replaced by a heteroatom, or represents a saturated or partially saturated carbocyclic ring which is optionally mono- or polysubstituted by identical or different substituents, or represents an aromatic ring which is optionally mono- or polysubstituted, where in each case optionally at least one carbonyl group may be present and/or where possible substituents are in each case as follows: hydrogen, cyano, halogen, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.3-C.sub.6)-cycloalkyl, halo-(C.sub.3-C.sub.8)-cycloalkyl, cyano-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl, (C.sub.1-C.sub.6)-alkylcarbonyl, (C.sub.1-C.sub.6)-haloalkylcarbonyl, aminocarbonyl, (C.sub.1-C.sub.6)-alkylaminocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminocarbonyl, (C.sub.1-C.sub.6)-alkylsulfonylamino, aminosulfonyl, (C.sub.1-C.sub.6)-alkylaminosulfonyl or di-(C.sub.1-C.sub.6)-alkylaminosulfonyl.

2. The compound of formula (I) according to claim 1, in which A.sup.1 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4a)—, A.sup.2 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4b)—, A.sup.3 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4c)—, X represents oxygen or sulfur, Y represents oxygen or sulfur, R.sup.1 represents (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.3-C.sub.8)-cycloalkyl, halo-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.1-C.sub.6)-alkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.1-C.sub.6)-haloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-haloalkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-cyanoalkyl, (C.sub.1-C.sub.6)-hydroxyalkyl, (C.sub.1-C.sub.6)-alkoxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkoxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-alkylthio-(C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-alkylsulfinyl-(C.sub.1-C.sub.6)-alkyl or (C.sub.1-C.sub.6)-alkylsulfonyl-(C.sub.1-C.sub.6)-alkyl, R.sup.2, R.sup.4a, R.sup.4b, R.sup.4c independently of one another represent hydrogen, cyano, halogen, (C.sub.1-C.sub.4)-alkyl, (C.sub.1-C.sub.4)-haloalkyl, (C.sub.2-C.sub.4)-alkenyl, (C.sub.2-C.sub.4)-haloalkenyl, (C.sub.2-C.sub.4)-alkynyl, (C.sub.2-C.sub.4)-haloalkynyl, (C.sub.1-C.sub.4)-alkoxy, (C.sub.1-C.sub.4)-haloalkoxy, (C.sub.1-C.sub.4)-alkylthio, (C.sub.1-C.sub.4)-haloalkylthio, (C.sub.1-C.sub.4)-alkylsulfinyl, (C.sub.1-C.sub.4)-haloalkylsulfinyl, (C.sub.1-C.sub.4)-alkylsulfonyl or (C.sub.1-C.sub.4)-haloalkylsulfonyl, R.sup.3 represents hydrogen, cyano, halogen, tri-(C.sub.1-C.sub.6)-alkylsilyl, (C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.8)-cycloalkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.8)-cycloalkyl, halo-(C.sub.3-C.sub.8)-cycloalkyl, cyano-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.1-C.sub.6)-cyanoalkyl, (C.sub.1-C.sub.6)-alkoxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-cyanoalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.2-C.sub.6)-cyanoalkynyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-cyanoalkoxy, (C.sub.1-C.sub.6)-alkylhydroxyimino, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkyl-(C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-haloalkyl-(C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl, (C.sub.1-C.sub.6)-alkylcarbonyl, (C.sub.1-C.sub.6)-haloalkylcarbonyl, (C.sub.1-C.sub.6)-alkoxycarbonyl, (C.sub.1-C.sub.6)-haloalkoxycarbonyl, aminocarbonyl, (C.sub.1-C.sub.6)-alkylaminocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminocarbonyl, (C.sub.3-C.sub.8)-cycloalkylaminocarbonyl, (C.sub.1-C.sub.6)-alkylsulfonylamino, aminosulfonyl, (C.sub.1-C.sub.6)-alkylaminosulfonyl, di-(C.sub.1-C.sub.6)-alkylaminosulfonyl, (C.sub.1-C.sub.6)-alkylsulfoximino or NHCO—(C.sub.1-C.sub.6)-alkyl ((C.sub.1-C.sub.6)-alkylcarbonylamino), R.sup.5, R.sup.6 independently of one another represent hydrogen, cyano, halogen, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.3-C.sub.6)-cycloalkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl, (C.sub.1-C.sub.6)-alkylsulfonyloxy, (C.sub.1-C.sub.6)-alkylcarbonyl, (C.sub.1-C.sub.6)-haloalkylcarbonyl, aminocarbonyl, (C.sub.1-C.sub.6)-alkylaminocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminocarbonyl, (C.sub.1-C.sub.6)-alkylsulfonylamino, aminosulfonyl, (C.sub.1-C.sub.6)-alkylaminosulfonyl or di-(C.sub.1-C.sub.6)-alkylaminosulfonyl, n represents 0, 1 or 2, V represents a saturated, partially saturated or heteroaromatic ring which is optionally mono- or polysubstituted by identical or different substituents, and in which at least one carbon atom is replaced by a heteroatom, or represents a saturated or partially saturated carbocyclic ring which is optionally mono- or polysubstituted by identical or different substituents, or represents an aromatic ring which is optionally mono- or polysubstituted by identical or different substituents, where in each case optionally at least one carbonyl group may be present and/or where possible substituents are in each case as follows: hydrogen, cyano, halogen, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.3-C.sub.6)-cycloalkyl, halo-(C.sub.3-C.sub.8)-cycloalkyl, cyano-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.6)-cycloalkyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl.

3. The compound of formula (I) according to claim 1, in which A.sup.1 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4a)—, A.sup.2 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4b)—, A.sup.3 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4c)—, X represents oxygen or sulfur, Y represents oxygen or sulfur, R.sup.1 represents (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl or (C.sub.3-C.sub.8)-cycloalkyl, R.sup.2, R.sup.4a, R.sup.4b, R.sup.4c independently of one another represent hydrogen, cyano, halogen, (C.sub.1-C.sub.4)-alkyl or (C.sub.1-C.sub.4)-haloalkyl, R.sup.3 represents hydrogen, cyano, halogen, (C.sub.3-C.sub.8)-cycloalkyl, (C.sub.3-C.sub.8)-cycloalkyl-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.8)-cycloalkyl, halo-(C.sub.3-C.sub.8)-cycloalkyl, cyano-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.1-C.sub.6)-cyanoalkyl, (C.sub.1-C.sub.6)-alkoxy-(C.sub.1-C.sub.6)-alkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-cyanoalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.2-C.sub.6)-cyanoalkynyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-cyanoalkoxy, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl or (C.sub.1-C.sub.6)-alkylsulfoximino, R.sup.5, R.sup.6 independently of one another represent hydrogen, cyano, halogen, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-alkenyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-alkynyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.3-C.sub.6)-cycloalkyl, (C.sub.3-C.sub.6)-cycloalkyl-(C.sub.3-C.sub.6)cycloalkyl, (C.sub.1-C.sub.6)-alkyl-(C.sub.3-C.sub.6)cycloalkyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl, (C.sub.1-C.sub.6)-alkylcarbonyl, (C.sub.1-C.sub.6)-haloalkylcarbonyl, aminocarbonyl, (C.sub.1-C.sub.6)-alkylaminocarbonyl, di-(C.sub.1-C.sub.6)-alkylaminocarbonyl, (C.sub.1-C.sub.6)-alkylsulfonylamino, aminosulfonyl, (C.sub.1-C.sub.6)-alkylaminosulfonyl or di-(C.sub.1-C.sub.6)-alkylaminosulfonyl, n represents 0, 1 or 2, V represents a 5- or 6-membered heteroaromatic ring which is optionally mono- or disubstituted by identical or different substituents, and in which at least one carbon atom is replaced by a heteroatom, or represents a 3-, 4- or 5-membered saturated carbocyclic ring which is optionally mono- or polysubstituted by identical or different substituents, or represents a 5- or 6-membered aromatic ring which is optionally mono- or polysubstituted by identical or different substituents, where in each case optionally at least one carbonyl group may be present and/or where possible substituents are in each case as follows: hydrogen, cyano, halogen, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.3-C.sub.6)-cycloalkyl, halo-(C.sub.3-C.sub.8)cycloalkyl, cyano-(C.sub.3-C.sub.8)-cycloalkyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkoxyimino, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl.

4. The compound of formula (I) according to claim 1, in which A.sup.1 represents nitrogen, A.sup.2 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4b)—, A.sup.3 represents nitrogen, ═N.sup.+(O.sup.−)— or ═C(R.sup.4c)—, X represents oxygen, Y represents oxygen or sulfur, R.sup.1 represents (C.sub.1-C.sub.4)-alkyl, (C.sub.1-C.sub.4)-haloalkyl or (C.sub.3-C.sub.6)-cycloalkyl, R.sup.2 represents hydrogen or (C.sub.1-C.sub.4)-alkyl, R.sup.3 represents hydrogen, cyano, halogen, (C.sub.1-C.sub.6)-alkyl, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.1-C.sub.6)-alkoxy, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl, (C.sub.1-C.sub.6)-haloalkylsulfonyl or (C.sub.1-C.sub.6)-alkoxyimino, R.sup.4b, R.sup.4c independently of one another represent hydrogen or (C.sub.1-C.sub.4)-alkyl, R.sup.5 represents halogen, (C.sub.1-C.sub.6)-haloalkyl, (C.sub.2-C.sub.6)-haloalkenyl, (C.sub.2-C.sub.6)-haloalkynyl, (C.sub.1-C.sub.6)-haloalkoxy, (C.sub.1-C.sub.6)-alkylthio, (C.sub.1-C.sub.6)-haloalkylthio, (C.sub.1-C.sub.6)-alkylsulfinyl, (C.sub.1-C.sub.6)-haloalkylsulfinyl, (C.sub.1-C.sub.6)-alkylsulfonyl or (C.sub.1-C.sub.6)-haloalkylsulfonyl, R.sup.6 represents hydrogen, n represents 0, 1 or 2, V represents cyclopropyl, cyclopentyl, phenyl or pyridinyl, each of which is optionally mono- or disubstituted by identical or different substituents from the group consisting of cyano, halogen, (C.sub.1-C.sub.2)-alkyl, (C.sub.1-C.sub.2)-haloalkyl, (C.sub.3-C.sub.4)-cycloalkyl, cyano-(C.sub.3-C.sub.4)-cycloalkyl, (C.sub.1-C.sub.2)-alkoxy, (C.sub.1-C.sub.2)-haloalkoxy, (C.sub.1-C.sub.2)-alkylthio, (C.sub.1-C.sub.2)-haloalkylthio, (C.sub.1-C.sub.2)-alkylsulfinyl, (C.sub.1-C.sub.2)-haloalkylsulfinyl, (C.sub.1-C.sub.2)-alkylsulfonyl, (C.sub.1-C.sub.2)-haloalkylsulfonyl.

5. The compound of formula (I) according to claim 1, in which A.sup.1 represents nitrogen, A.sup.2 represents ═C(R.sup.4b)—, A.sup.3 represents ═C(R.sup.4c)— or nitrogen, X represents oxygen, Y represents oxygen, R.sup.1 represents methyl, ethyl, n-propyl or isopropyl, R.sup.2 represents hydrogen, R.sup.3 represents hydrogen, R.sup.4b represents hydrogen, R.sup.4c represents hydrogen, R.sup.5 represents bromine, fluoromethyl, difluoromethyl, trifluoromethyl, fluoroethyl (CH.sub.2CFH.sub.2, CHFCH.sub.3), difluoroethyl (CF.sub.2CH.sub.3, CH.sub.2CHF.sub.2, CHFCFH.sub.2), trifluoroethyl, (CH.sub.2CF.sub.3, CHFCHF.sub.2, CF.sub.2CFH.sub.2), tetrafluoroethyl (CHFCF.sub.3, CF.sub.2CHF.sub.2), pentafluoroethyl, trifluoromethoxy, tetrafluoroethoxy (OCHFCF.sub.3, OCF.sub.2CHF.sub.2), pentafluoroethoxy, difluorochloromethoxy, dichlorofluoromethoxy, trifluoromethylthio, trifluoromethylsulfinyl, difluorochloromethylsulfonyl, trifluoromethylsulfonyl or pentafluoroethylsulfonyl, R.sup.6 represents hydrogen, n represents 2, V represents cyclopropyl which is optionally monosubstituted by trifluoromethyl, represents cyclopentyl, represents phenyl which is optionally mono- or disubstituted by identical or different substituents from the group consisting of cyano, fluorine, chlorine, bromine, iodine, methyl, ethyl, trifluoromethyl, methoxy, trifluoromethoxy or cyanocyclopropyl or represents pyridinyl which is optionally monosubstituted by fluorine or methoxy.

6. The compound of formula (I) according to claim 1, in which A.sup.1 represents nitrogen, A.sup.2 represents ═CH—, A.sup.3 represents ═CH— or nitrogen, X represents oxygen, Y represents oxygen, R.sup.1 represents ethyl, R.sup.2 represents hydrogen, R.sup.3 represents hydrogen, R.sup.5 represents bromine, trifluoromethyl, pentafluoroethyl, trifluoromethoxy, tetrafluoroethoxy, pentafluoroethoxy, difluorochloromethylsulfonyl, trifluoromethylsulfonyl or pentafluoroethylsulfonyl, R.sup.6 represents hydrogen, n represents 2, V represents cyclopropyl which is optionally monosubstituted by trifluoromethyl, represents cyclopentyl, represents phenyl which is optionally mono- or disubstituted by identical or different substituents from the group consisting of cyano, fluorine, chlorine, bromine, iodine or cyanocyclopropyl or represents pyridinyl which is optionally monosubstituted by fluorine or methoxy.

7. The compound of formula (I) according to claim 1, in which the compound has a structure below: TABLE-US-00013 Ex. Structure I-01 I-02 I-03 I-04 I-05 I-06 I-07 I-08 I-09 I-10 I-11 I-12 I-13 I-14 I-15 I-16 I-17 I-18 I-19 I-20 I-21 I-22 I-23 I-24 I-25 I-26 I-27 I-28 I-29 I-30 I-31 I-32 I-33 I-34 I-35 I-36 I-37 I-38 I-39 I-40 I-41 I-42 I-43 I-44 I-45 I-46 I-47 I-48 I-49 I-50 I-51 I-52 I-53 I-54 I-55 I-56

8. An agrochemical formulation comprising one or more compounds of formula (I) according to claim 1 and one or more extenders and/or surfactants.

9. The agrochemical formulation according to claim 8, additionally comprising a further agrochemically active compound.

10. A method for controlling one or more animal pests, comprising allowing a compound of formula (I) according to claim 1 or an agrochemical formulation thereof is allowed to act on the animal pests and/or a habitat thereof.

11. A product comprising one or more compounds of formula (I) according to claim 1 or one or more agrochemical formulations thereof for controlling one or more animal pests.

Description

PREPARATION EXAMPLES

Example I-14

2-[5-Ethylsulfonyl-6-[5-(trifluoromethylsulfonyl)-1,3-benzoxazol-2-yl]-2-pyridyl]-4-(3-fluorophenyl)-1,2,4-triazol-3-one

[0538] ##STR00004##

[0539] 200 mg (0.45 mmol) of 2-(3-ethylsulfonyl-6-fluoro-2-pyridyl)-5-(trifluoromethylsulfonyl)-1,3-benzoxazole were dissolved in 10 ml of acetonitrile, 223.0 mg (0.68 mmol) of caesium carbonate, 37.9 mg (0.22 mmol) of potassium iodide and 163.5 mg (0.91 mmol) of 4-(3-fluorophenyl)-1H-1,2,4-triazol-5-one were added and the mixture was stirred at room temperature for 20 h. The reaction mixture was then filtered through silica gel using ethyl acetate, the mother liquor was freed of the solvent under reduced pressure and the residue was purified by column chromatography via preparative HPLC using a water/acetonitrile gradient as mobile phase.

[0540] logP (neutral): 3.43; MH.sup.+: 598; .sup.1H-NMR (400 MHz, D6-DMSO) δ ppm: 1.29 (t, 3H), 3.87 (q, 2H), 7.30-7.34 (m, 1H), 7.61-7.73 (m, 3H), 8.36 (d, 1H), 8.44 (d, 1H), 8.62 (d, 1H), 8.75 (d, 1H), 8.86 (s, 1H), 8.93 (s, 1H).

2-(3-Ethylsulfonyl-6-fluoro-2-pyridyl)-5-(trifluoromethylsulfonyl)-1,3-benzoxazole

[0541] ##STR00005##

[0542] 3.56 g (8.32 mmol) of 2-(3-ethylsulfanyl-6-fluoro-2-pyridyl)-5-(trifluoromethylsulfonyl)-1,3-benzoxazole were dissolved in 200 ml of dichloromethane, 3.75 g (81.5 mmol) of formic acid and 7.48 g (76.9 mmol) of 35% strength hydrogen peroxide were added at room temperature and the mixture was then stirred at room temperature for 17 h. The mixture was diluted with water and sodium bisulfite solution was added, the mixture was stirred for 1 h and saturated sodium hydrogencarbonate solution was then added. The organic phase was separated off, the aqueous phase was extracted twice with dichloromethane and the combined organic phases were then freed of the solvent under reduced pressure. The residue was purified by column chromatography purification by means of preparative HPLC with a water/acetonitrile gradient as eluent.

[0543] logP (neutral): 3.11; MH.sup.+: 439; .sup.1H-NMR (600 MHz, D.sub.6-DMSO) δ ppm: 1.29 (t, 3H), 3.93 (q, 2H), 7.87 (d, 1H), 8.35 (d, 1H), 8.42 (d, 1H), 8.76-8.79 (m, 1H), 8.87 (s, 1H).

2-(3-Ethylsulfanyl-6-fluoro-2-pyridyl)-5-(trifluoromethylsulfonyl)-1,3-benzoxazole

[0544] ##STR00006##

[0545] 825 mg (1.74 mmol) of 2-(3,6-difluoro-2-pyridyl)-5-(trifluoromethylsulfonyl)-1,3-benzoxazole were dissolved in 50 ml of tetrahydrofuran, the mixture was cooled to −20° C. and 77 mg (1.91 mmol) of sodium hydride were added. The reaction was stirred for another 1 h, and 119 mg (1.91 mmol) of ethanethiol, dissolved in 6 ml of tetrahydrofuran, were then added dropwise over 30 minutes at −20 to −10° C. The reaction was stirred for another 2 h at −15 to −8° C. and then poured into ice-water, and the precipitated solid was filtered off. The residue was reacted further without further purification.

[0546] logP (acidic): 4.13; MH.sup.+: 407; .sup.1H-NMR (400 MHz, D.sub.6-DMSO) δ ppm: 1.32 (t, 3H), 3.16 (q, 2H), 7.52-7.55 (m, 1H), 8.24-8.28 (m, 2H), 8.35 (d, 1H), 8.74 (s, 1H).

2-(3,6-Difluoro-2-pyridyl)-5-(trifluoromethylsulfonyl)-1,3-benzoxazole

[0547] ##STR00007##

[0548] 3.35 g (13.8 mmol) of 2-amino-4-(trifluoromethylsulfonyl)phenol, 2.43 g (15.2 mmol) of 3,6-difluoropyridine-2-carboxylic acid and 3.99 g (20.8 mmol) of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDCI) were stirred in 85 ml of pyridine at room temperature for 72 h. The reaction mixture was freed of solvent under reduced pressure, water was added and the mixture was extracted three times with ethyl acetate. The organic phases were combined and dried over sodium sulfate, and the solvent was then distilled off under reduced pressure. The residue was recrystallized from ethyl acetate, filtered off and dried. 1.36 g (3.43 mmol) of the intermediate obtained in this manner were initially charged together with 1.17 g (4.45 mmol) of triphenylphosphine in 20 ml of tetrahydrofuran, and diethyl azodicarboxylate (DEAD, 40% in toluene) was then added dropwise and the mixture was stirred at 50° C. for 6 h. The solvent was then distilled off under reduced pressure and the residue was purified by column chromatography via preparative HPLC using a water/acetonitrile gradient as mobile phase.

[0549] logP (neutral): 3.06; MH.sup.+: 365; .sup.1H-NMR (400 MHz, D.sub.6-DMSO) δ ppm: 7.67-7.71 (m, 1H), 8.27-8.39 (m, 3H), 8.80 (s, 1H).

[0550] In analogy to the examples and according to the above-described preparation processes, the following compounds of the formula (I) can be obtained:

TABLE-US-00001 Ex. Structure I-01 [00008] I-01: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8675 (15.1); 8.8594 (5.4); 8.7602 (5.2); 8.7380 (7.6); 8.6475 (7.8); 8.6252 (5.7); 8.4523 (4.0); 8.4304 (6.6); 8.3697 (3.4); 8.3656 (3.3); 8.3479 (2.1); 8.3436 (2.1); 7.7561 (4.4); 7.7532 (5.9); 7.7342 (7.0); 7.6043 (3.9); 7.5853 (6.8); 7.5649 (4.3); 7.4792 (2.6); 7.4605 (3.8); 7.4421 (1.4); 3.9016 (1.9); 3.8832 (6.6); 3.8647 (6.6); 3.8462 (2.0); 3.3252 (107.9); 2.6756 (0.8); 2.6714 (1.0); 2.6669 (0.8); 2.5246 (3.6); 2.5068 (130.0); 2.5024 (168.2); 2.4979 (123.2); 2.3337 (0.8); 2.3292 (1.0); 2.3247 (0.8); 1.3086 (7.2); 1.2901 (16.0); 1.2716 (7.0); 0.1459 (0.4); 0.0079 (3.7); −0.0002 (93.8); −0.0084 (4.1); −0.1497 (0.4) 1−02 [00009] I-02: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8806 (14.4); 8.8617 (4.8); 8.8574 (4.8); 8.7626 (5.6); 8.7403 (7.8); 8.6306 (7.8); 8.6084 (6.1); 8.4505 (3.8); 8.4287 (6.3); 8.3691 (3.2); 8.3647 (3.1); 8.3473 (1.9); 8.3427 (2.0); 8.3155 (0.4); 7.8148 (0.8); 7.8072 (7.4); 7.8020 (2.6); 7.7904 (3.0); 7.7850 (10.7); 7.7776 (1.2); 7.7721 (0.4); 7.6841 (1.2); 7.6768 (10.4); 7.6714 (3.1); 7.6599 (2.6); 7.6545 (7.5); 7.6470 (0.8); 7.0826 (0.3); 5.7556 (3.4); 3.9018 (1.8); 3.8834 (6.3); 3.8649 (6.4); 3.8465 (1.9); 3.3246 (107.6); 2.6803 (0.4); 2.6759 (0.8); 2.6714 (1.2); 2.6669 (0.8); 2.6623 (0.4); 2.5249 (3.4); 2.5201 (5.3); 2.5114 (69.2); 2.5070 (141.4); 2.5025 (186.1); 2.4979 (134.0); 2.4935 (65.0); 2.3384 (0.4); 2.3337 (0.8); 2.3292 (1.2); 2.3248 (0.8); 1.3540 (3.0); 1.3074 (7.0); 1.2890 (16.0); 1.2705 (6.9); 1.2335 (0.7); 0.1459 (0.8); 0.0079 (6.6); −0.0002 (192.1); −0.0085 (7.4); −0.1496 (0.8) I-03 [00010] I-03: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8451 (4.8); 8.8410 (4.8); 8.7082 (5.2); 8.6860 (7.7); 8.5962 (7.6); 8.5740 (5.5); 8.4345 (3.8); 8.4127 (6.6); 8.3582 (3.7); 8.3510 (13.9); 8.3365 (2.0); 8.3322 (2.0); 8.3152 (0.5); 5.7554 (2.1); 3.8712 (1.9); 3.8528 (6.4); 3.8343 (6.5); 3.8158 (1.9); 3.5073 (0.5); 3.3250 (189.7); 3.1037 (0.7); 3.0928 (1.1); 3.0871 (1.4); 3.0765 (2.7); 3.0677 (1.4); 3.0608 (1.2); 3.0492 (0.7); 2.8914 (0.8); 2.7318 (0.7); 2.6759 (1.0); 2.6714 (1.4); 2.6669 (1.0); 2.5418 (1.2); 2.5247 (4.0); 2.5113 (83.5); 2.5070 (167.6); 2.5025 (219.4); 2.4980 (159.3); 2.4936 (78.4); 2.3338 (1.0); 2.3293 (1.4); 2.3247 (1.0); 1.6093 (0.4); 1.2899 (7.1); 1.2715 (16.0); 1.2530 (7.2); 1.2343 (2.0); 0.9902 (0.5); 0.9776 (3.0); 0.9707 (8.2); 0.9679 (9.4); 0.9650 (9.1); 0.9524 (3.7); 0.9488 (4.8); 0.9432 (3.2); 0.9209 (0.4); 0.8538 (0.3); 0.1460 (0.9); 0.0079 (7.2); −0.0001 (196.1); −0.0084 (7.8); −0.1496 (0.9) I-04 [00011] I-04: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8650 (4.6); 8.8607 (4.7); 8.8317 (13.7); 8.7613 (5.6); 8.7390 (8.0); 8.6354 (7.7); 8.6132 (5.9); 8.4517 (4.0); 8.4299 (6.7); 8.3709 (3.2); 8.3663 (3.1); 8.3490 (1.9); 8.3444 (1.9); 7.8065 (0.4); 7.7977 (4.2); 7.7923 (1.6); 7.7856 (4.5); 7.7804 (2.7); 7.7750 (5.2); 7.7686 (1.7); 7.7629 (4.8); 7.7542 (0.5); 7.4764 (0.4); 7.4675 (4.7); 7.4619 (1.5); 7.4549 (0.7); 7.4501 (1.7); 7.4454 (7.8); 7.4407 (1.8); 7.4290 (1.4); 7.4233 (4.2); 7.4147 (0.4); 3.9023 (1.7); 3.8838 (6.1); 3.8653 (6.2); 3.8469 (1.8); 3.3320 (149.4); 2.6809 (0.4); 2.6763 (0.8); 2.6719 (1.2); 2.6673 (0.9); 2.6627 (0.4); 2.5253 (3.9); 2.5205 (5.9); 2.5118 (69.1); 2.5074 (139.7); 2.5029 (184.0); 2.4983 (135.1); 2.4938 (66.4); 2.3387 (0.4); 2.3343 (0.8); 2.3297 (1.2); 2.3252 (0.8); 2.3207 (0.4); 2.0757 (0.6); 1.3067 (7.0); 1.2883 (16.0); 1.2698 (6.8); 0.1457 (1.0); 0.0078 (7.8); −0.0002 (223.0); −0.0086 (8.6); −0.1498 (1.0) I-05 [00012] I-05: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8855 (12.9); 8.8662 (4.8); 8.8625 (5.0); 8.7656 (5.3); 8.7434 (7.4); 8.6330 (7.2); 8.6107 (5.7); 8.4541 (3.9); 8.4322 (6.5); 8.3730 (3.2); 8.3689 (3.2); 8.3512 (1.9); 8.3468 (2.0); 8.3192 (0.4); 8.1409 (6.2); 7.8142 (5.7); 7.8090 (2.3); 7.7974 (2.8); 7.7919 (11.6); 7.7856 (1.7); 7.7530 (1.5); 7.7464 (11.4); 7.7411 (3.2); 7.7295 (2.2); 7.7241 (6.2); 3.9051 (1.8); 3.8867 (6.2); 3.8682 (6.4); 3.8498 (1.9); 3.3305 (97.0); 2.6798 (1.0); 2.6752 (1.5); 2.6707 (1.1); 2.5457 (0.7); 2.5287 (3.6); 2.5150 (83.8); 2.5108 (174.7); 2.5063 (234.0); 2.5018 (174.1); 2.4978 (88.2); 2.3375 (1.0); 2.3331 (1.5); 2.3287 (1.1); 2.0785 (0.5); 1.3106 (7.1); 1.2922 (16.0); 1.2737 (7.0); 0.0038 (0.5) I-06 [00013] I-06: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 9.0148 (13.1); 8.8654 (5.0); 8.8612 (5.0); 8.7751 (6.6); 8.7528 (7.4); 8.6699 (2.4); 8.6242 (7.2); 8.6020 (5.9); 8.4521 (3.9); 8.4303 (6.6); 8.4215 (1.3); 8.4000 (1.4); 8.3715 (3.3); 8.3672 (3.3); 8.3496 (2.0); 8.3451 (2.1); 8.3137 (2.5); 8.3113 (2.5); 8.1511 (1.3); 8.1297 (1.4); 8.1061 (5.4); 8.1013 (2.3); 8.0892 (3.1); 8.0840 (11.2); 8.0414 (11.0); 8.0363 (3.1); 8.0242 (2.3); 8.0192 (5.6); 7.9811 (1.3); 7.9590 (2.0); 7.8833 (1.9); 7.8781 (0.6); 7.8662 (0.5); 7.8612 (1.3); 7.3972 (0.5); 7.3856 (0.5); 7.3683 (0.4); 5.7395 (2.3); 3.9064 (1.8); 3.8879 (6.3); 3.8694 (6.5); 3.8510 (2.0); 3.8209 (0.4); 3.8024 (1.2); 3.7839 (1.2); 3.7651 (0.4); 3.3256 (180.0); 2.6759 (1.0); 2.6714 (1.3); 2.6670 (1.0); 2.5418 (2.2); 2.5248 (4.0); 2.5113 (83.3); 2.5070 (167.0); 2.5025 (218.5); 2.4980 (158.1); 2.4936 (77.6); 2.3337 (1.0); 2.3293 (1.3); 2.3248 (1.0); 2.0749 (0.5); 1.6487 (0.5); 1.3089 (7.1); 1.2904 (16.0); 1.2719 (7.2); 1.2659 (2.1); 1.2471 (3.2); 1.2287 (1.5); 0.0079 (1.2); −0.0002 (34.3); −0.0085 (1.4) I-07 [00014] I-07: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8294 (14.4); 8.8020 (5.3); 8.7977 (5.2); 8.7591 (5.5); 8.7369 (7.8); 8.6320 (7.7); 8.6097 (6.0); 8.4306 (4.4); 8.4154 (0.9); 8.4088 (6.6); 8.3313 (3.4); 8.3268 (3.2); 8.3159 (0.7); 8.3094 (2.3); 8.3049 (2.2); 8.0049 (0.4); 7.9840 (0.4); 7.7974 (4.3); 7.7919 (1.9); 7.7853 (4.7); 7.7800 (3.0); 7.7747 (5.2); 7.7681 (2.0); 7.7626 (4.8); 7.7538 (0.5); 7.4756 (0.6); 7.4668 (4.9); 7.4611 (1.6); 7.4448 (8.2); 7.4282 (1.6); 7.4227 (4.3); 7.4141 (0.4); 3.8996 (1.9); 3.8812 (6.5); 3.8626 (6.6); 3.8443 (2.0); 3.5532 (0.4); 3.5351 (0.4); 3.3275 (155.4); 2.6759 (0.9); 2.6715 (1.1); 2.6670 (0.9); 2.5113 (76.0); 2.5070 (144.4); 2.5026 (184.2); 2.4981 (132.1); 2.4937 (64.0); 2.3339 (0.8); 2.3293 (1.1); 2.3249 (0.8); 2.0750 (9.1); 1.3055 (7.2); 1.2871 (16.0); 1.2686 (7.1); 1.2078 (0.5); 1.1890 (0.9); 1.1700 (0.7); −0.0002 (4.6) I-08 [00015] I-08: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8811 (14.1); 8.8018 (4.8); 8.7978 (4.9); 8.7611 (5.7); 8.7389 (8.1); 8.6282 (7.9); 8.6060 (6.3); 8.4304 (4.1); 8.4093 (6.2); 8.4087 (6.2); 8.3312 (3.1); 8.3267 (3.1); 8.3162 (0.6); 8.3094 (2.1); 8.3047 (2.1); 7.8145 (0.7); 7.8070 (7.5); 7.8017 (2.6); 7.7901 (3.0); 7.7846 (10.8); 7.7773 (1.2); 7.6847 (1.2); 7.6774 (10.5); 7.6720 (3.0); 7.6604 (2.6); 7.6550 (7.6); 7.6475 (0.7); 3.9010 (1.8); 3.8825 (6.2); 3.8640 (6.3); 3.8456 (1.9); 3.3266 (107.7); 2.6761 (0.7); 2.6715 (1.0); 2.6670 (0.7); 2.5250 (2.5); 2.5203 (3.8); 2.5115 (58.8); 2.5071 (121.7); 2.5025 (161.4); 2.4980 (116.6); 2.4936 (55.9); 2.3340 (0.7); 2.3293 (1.0); 2.3249 (0.7); 2.0752 (0.9); 1.3057 (7.0); 1.2872 (16.0); 1.2687 (6.9); −0.0001 (5.0) I-09 [00016] I-09: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8829 (14.3); 8.8007 (4.8); 8.7964 (4.8); 8.7601 (5.8); 8.7379 (8.2); 8.6266 (7.9); 8.6044 (6.4); 8.4302 (4.1); 8.4083 (6.2); 8.3304 (3.1); 8.3258 (3.0); 8.3159 (0.5); 8.3086 (2.0); 8.3039 (2.1); 7.8157 (0.6); 7.8091 (6.0); 7.8036 (2.2); 7.7923 (3.0); 7.7867 (12.0); 7.7802 (1.6); 7.7490 (1.6); 7.7425 (11.8); 7.7370 (2.9); 7.7256 (2.2); 7.7201 (6.2); 7.7134 (0.6); 3.9009 (1.7); 3.8825 (6.2); 3.8639 (6.3); 3.8455 (1.8); 3.3265 (67.6); 2.6763 (0.5); 2.6718 (0.7); 2.6673 (0.5); 2.5253 (1.8); 2.5206 (2.7); 2.5119 (41.9); 2.5074 (86.0); 2.5029 (113.8); 2.4983 (81.5); 2.4938 (38.6); 2.3343 (0.5); 2.3297 (0.7); 2.3251 (0.5); 2.0754 (2.4); 1.3057 (6.9); 1.2873 (16.0); 1.2687 (6.8); −0.0002 (3.3) I-10 [00017] I-10: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 9.0144 (14.2); 8.8019 (5.0); 8.7978 (5.2); 8.7730 (6.0); 8.7508 (7.6); 8.6215 (7.4); 8.5993 (6.2); 8.5012 (0.5); 8.4803 (0.6); 8.4315 (4.2); 8.4097 (6.3); 8.3942 (0.5); 8.3320 (3.2); 8.3275 (3.2); 8.3149 (0.9); 8.3101 (2.2); 8.3056 (2.2); 8.1902 (1.0); 8.1051 (5.4); 8.0999 (2.7); 8.0882 (3.1); 8.0829 (11.3); 8.0415 (11.2); 8.0364 (3.2); 8.0244 (2.2); 8.0193 (5.6); 3.9042 (1.9); 3.8859 (6.4); 3.8674 (6.5); 3.8490 (1.9); 3.3613 (0.8); 3.3214 (18.0); 2.6756 (1.2); 2.6711 (1.6); 2.6666 (1.2); 2.6622 (0.6); 2.5414 (1.0); 2.5244 (5.9); 2.5111 (99.8); 2.5067 (199.0); 2.5021 (261.2); 2.4976 (191.4); 2.4932 (95.0); 2.3336 (1.2); 2.3290 (1.6); 2.3245 (1.1); 2.3199 (0.6); 2.0743 (5.3); 1.3077 (7.1); 1.2892 (16.0); 1.2708 (6.9); 1.2603 (0.9); 1.2418 (1.4); 1.2233 (0.6); 0.1459 (0.8); 0.0079 (7.4); −0.0002 (178.6); −0.0084 (7.1); −0.1496 (0.8) I-11 [00018] I-11: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8720 (15.6); 8.8014 (4.8); 8.7970 (4.7); 8.7564 (5.8); 8.7342 (8.4); 8.6225 (8.0); 8.6003 (6.6); 8.4297 (4.1); 8.4077 (6.1); 8.3301 (3.1); 8.3254 (2.9); 8.3082 (2.0); 8.3035 (2.0); 7.9639 (0.9); 7.9572 (8.4); 7.9521 (2.7); 7.9403 (3.0); 7.9352 (9.8); 7.9284 (1.0); 7.5972 (1.1); 7.5905 (9.5); 7.5854 (2.8); 7.5736 (2.8); 7.5685 (8.7); 7.5616 (0.8); 5.7578 (4.6); 3.8983 (1.7); 3.8799 (6.2); 3.8614 (6.2); 3.8429 (1.8); 3.3229 (65.1); 2.6755 (0.7); 2.6709 (1.0); 2.6664 (0.7); 2.6621 (0.3); 2.5414 (0.7); 2.5245 (2.9); 2.5197 (4.4); 2.5111 (60.1); 2.5066 (121.0); 2.5020 (157.7); 2.4974 (111.8); 2.4929 (52.2); 2.3335 (0.7); 2.3288 (0.9); 2.3243 (0.7); 1.3034 (6.9); 1.2849 (16.0); 1.2664 (6.8); 1.2360 (0.7); −0.0002 (3.1) I-12 [00019] I-12: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8723 (14.0); 8.8587 (5.0); 8.8545 (5.1); 8.7578 (5.5); 8.7356 (7.8); 8.6262 (7.6); 8.6040 (6.0); 8.4486 (4.0); 8.4268 (6.6); 8.3669 (3.3); 8.3624 (3.3); 8.3451 (2.0); 8.3404 (2.2); 8.3147 (0.5); 8.1347 (4.4); 7.9628 (0.9); 7.9560 (8.2); 7.9512 (3.0); 7.9391 (3.0); 7.9341 (9.6); 7.9275 (1.2); 7.5981 (1.1); 7.5914 (9.2); 7.5866 (3.2); 7.5744 (2.8); 7.5695 (8.6); 7.5628 (1.0); 3.8997 (1.8); 3.8813 (6.4); 3.8628 (6.5); 3.8444 (1.9); 3.3226 (42.4); 2.6758 (0.9); 2.6713 (1.2); 2.6669 (0.9); 2.5416 (0.8); 2.5247 (3.9); 2.5199 (5.8); 2.5112 (72.1); 2.5069 (145.2); 2.5024 (190.8); 2.4978 (140.0); 2.4935 (69.5); 2.3381 (0.4); 2.3337 (0.8); 2.3293 (1.2); 2.3247 (0.9); 2.0743 (1.6); 1.3516 (0.4); 1.3061 (7.1); 1.2876 (16.0); 1.2691 (7.0); 1.2483 (0.4); 1.2300 (0.4); 0.1458 (0.7); 0.0079 (5.6); −0.0002 (166.3); −0.0085 (6.4); −0.1497 (0.8) I-13 [00020] I-13: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9252 (13.6); 8.8664 (4.1); 8.8620 (4.0); 8.7672 (5.2); 8.7449 (7.2); 8.6269 (7.0); 8.6047 (5.8); 8.4534 (3.3); 8.4526 (3.2); 8.4315 (5.5); 8.3721 (2.7); 8.3677 (2.6); 8.3503 (1.6); 8.3457 (1.6); 7.9244 (2.9); 7.9194 (5.5); 7.9144 (3.0); 7.7875 (1.6); 7.7851 (1.9); 7.7824 (1.6); 7.7800 (1.6); 7.7673 (2.2); 7.7649 (2.2); 7.7622 (2.3); 7.7597 (2.0); 7.6386 (2.3); 7.6184 (4.9); 7.5981 (2.9); 7.5457 (2.4); 7.5432 (2.7); 7.5407 (2.6); 7.5382 (2.3); 7.5255 (1.5); 7.5230 (1.6); 7.5204 (1.6); 7.5180 (1.4); 5.7578 (16.0); 3.9048 (1.5); 3.8863 (5.4); 3.8678 (5.4); 3.8493 (1.6); 3.3229 (54.6); 2.6757 (0.6); 2.6712 (0.8); 2.6666 (0.6); 2.5247 (2.1); 2.5198 (3.3); 2.5112 (46.4); 2.5067 (93.8); 2.5022 (122.0); 2.4976 (86.9); 2.4930 (41.0); 2.3336 (0.5); 2.3290 (0.7); 2.3244 (0.5); 1.3084 (5.9); 1.2899 (13.8); 1.2714 (5.8); 0.0080 (0.9); −0.0002 (27.8); −0.0085 (0.9) I-14 [00021] I-14: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9253 (13.9); 8.8673 (4.9); 8.8631 (4.8); 8.7677 (5.6); 8.7454 (7.8); 8.6318 (7.6); 8.6096 (6.0); 8.4535 (3.8); 8.4317 (6.4); 8.3724 (3.2); 8.3681 (3.2); 8.3506 (2.0); 8.3463 (2.0); 7.7349 (1.9); 7.7321 (2.2); 7.7271 (1.6); 7.7113 (1.4); 7.7064 (2.4); 7.7011 (1.7); 7.6754 (1.2); 7.6708 (0.8); 7.6581 (5.1); 7.6553 (4.7); 7.6505 (3.2); 7.6470 (2.6); 7.6424 (2.4); 7.6270 (2.2); 7.6069 (0.8); 7.3443 (0.9); 7.3382 (1.5); 7.3308 (0.9); 7.3267 (1.0); 7.3214 (2.1); 7.3157 (1.5); 7.3027 (1.0); 7.2992 (1.2); 7.2930 (0.8); 5.7578 (8.7); 3.9038 (1.8); 3.8854 (6.3); 3.8669 (6.3); 3.8485 (1.9); 3.3223 (101.8); 2.6753 (1.2); 2.6707 (1.7); 2.6662 (1.2); 2.5603 (0.4); 2.5411 (1.1); 2.5242 (5.0); 2.5107 (102.7); 2.5063 (205.2); 2.5018 (266.6); 2.4972 (192.0); 2.4928 (92.8); 2.3332 (1.1); 2.3286 (1.6); 2.3241 (1.1); 1.3080 (7.0); 1.2895 (16.0); 1.2710 (7.1); 1.2340 (0.6); 1.1692 (0.7); 0.0080 (1.7); −0.0001 (53.8); −0.0084 (1.9) I-15 [00022] I-15: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9197 (11.5); 8.8659 (4.0); 8.8617 (4.0); 8.7660 (4.4); 8.7437 (6.1); 8.6254 (6.0); 8.6032 (4.9); 8.4533 (3.1); 8.4315 (5.2); 8.3717 (2.7); 8.3674 (2.6); 8.3498 (1.6); 8.3455 (1.6); 8.0477 (2.8); 8.0429 (5.1); 8.0380 (3.0); 7.8220 (1.7); 7.8199 (1.9); 7.8171 (1.8); 7.8149 (1.6); 7.8018 (2.0); 7.7996 (2.1); 7.7968 (2.2); 7.7946 (1.8); 7.6772 (1.6); 7.6749 (1.8); 7.6726 (1.8); 7.6704 (1.5); 7.6571 (2.3); 7.6548 (2.5); 7.6525 (2.5); 7.6503 (2.1); 7.5684 (3.0); 7.5482 (4.5); 7.5280 (1.9); 5.7578 (16.0); 3.9046 (1.5); 3.8861 (5.0); 3.8676 (5.1); 3.8493 (1.6); 3.3232 (36.9); 2.6758 (0.5); 2.6714 (0.6); 2.6669 (0.5); 2.5416 (0.4); 2.5248 (2.1); 2.5112 (42.9); 2.5069 (83.9); 2.5024 (107.8); 2.4978 (79.0); 2.4935 (39.5); 2.3336 (0.5); 2.3292 (0.7); 2.3247 (0.5); 1.3084 (5.5); 1.2899 (12.4); 1.2715 (5.5); 0.0079 (0.7); −0.0002 (19.2); −0.0083 (0.9) I-16 [00023] I-16: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8953 (11.0); 8.8660 (3.5); 8.8617 (3.5); 8.7618 (4.3); 8.7396 (6.1); 8.6243 (5.9); 8.6021 (4.8); 8.4530 (2.9); 8.4310 (4.8); 8.3715 (2.4); 8.3670 (2.3); 8.3497 (1.4); 8.3451 (1.4); 8.1689 (2.6); 8.1644 (4.3); 8.1597 (2.7); 7.8346 (1.6); 7.8324 (2.1); 7.8287 (1.7); 7.8125 (3.8); 7.8090 (3.5); 7.7938 (1.9); 7.7918 (1.6); 7.7885 (2.0); 7.3956 (2.5); 7.3755 (4.2); 7.3554 (2.1); 5.7576 (16.0); 3.9028 (1.3); 3.8843 (4.6); 3.8657 (4.7); 3.8473 (1.4); 3.3218 (71.8); 2.6797 (0.4); 2.6753 (0.9); 2.6706 (1.2); 2.6661 (0.9); 2.6615 (0.4); 2.5410 (1.0); 2.5241 (3.6); 2.5194 (5.4); 2.5107 (72.2); 2.5063 (147.6); 2.5017 (194.2); 2.4971 (139.1); 2.4926 (66.3); 2.3376 (0.4); 2.3331 (0.8); 2.3285 (1.1); 2.3240 (0.8); 2.3194 (0.4); 1.3071 (5.2); 1.2887 (12.1); 1.2702 (5.2); 0.0080 (1.2); −0.0002 (39.7); −0.0085 (1.2) I-17 [00024] I-17: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8674 (15.5); 8.8603 (5.4); 8.8560 (5.2); 8.7579 (5.4); 8.7357 (7.7); 8.6345 (7.8); 8.6232 (0.4); 8.6123 (6.0); 8.6023 (0.3); 8.4497 (4.2); 8.4279 (6.9); 8.4129 (0.3); 8.3679 (3.3); 8.3635 (3.4); 8.3462 (2.0); 8.3416 (2.1); 8.3145 (0.5); 7.7886 (1.0); 7.7817 (7.6); 7.7771 (2.8); 7.7651 (2.9); 7.7601 (9.6); 7.7539 (1.2); 7.5545 (1.3); 7.5480 (8.9); 7.5432 (3.1); 7.5313 (2.6); 7.5263 (7.8); 7.5198 (0.9); 3.8981 (1.9); 3.8797 (6.5); 3.8612 (6.6); 3.8427 (2.0); 3.3193 (54.0); 2.6753 (1.0); 2.6708 (1.4); 2.6663 (1.0); 2.6622 (0.5); 2.5242 (4.2); 2.5107 (82.0); 2.5064 (165.8); 2.5019 (218.9); 2.4973 (160.8); 2.4929 (80.2); 2.3331 (1.0); 2.3286 (1.3); 2.3242 (1.0); 2.3199 (0.5); 2.0742 (1.1); 1.8309 (2.3); 1.8178 (6.4); 1.8109 (7.1); 1.7996 (2.7); 1.7603 (0.3); 1.6024 (2.7); 1.5900 (6.8); 1.5831 (6.9); 1.5694 (2.2); 1.3063 (7.1); 1.2879 (16.0); 1.2694 (7.2); 1.2349 (0.4); 1.1692 (1.0); 0.0078 (0.4); −0.0002 (14.1); −0.0083 (0.5) I-18 [00025] I-18: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8670 (13.7); 8.7999 (4.0); 8.7956 (4.0); 8.7565 (4.6); 8.7342 (6.6); 8.6323 (6.7); 8.6101 (5.3); 8.4303 (3.4); 8.4083 (5.2); 8.3301 (2.5); 8.3257 (2.5); 8.3146 (1.1); 8.3085 (1.7); 8.3037 (1.7); 7.7819 (6.2); 7.7769 (2.1); 7.7653 (2.3); 7.7601 (7.8); 7.7536 (0.9); 7.5552 (1.0); 7.5487 (7.3); 7.5436 (2.3); 7.5319 (2.1); 7.5268 (6.2); 7.5202 (0.7); 3.8967 (1.5); 3.8783 (5.2); 3.8598 (5.3); 3.8414 (1.6); 3.3190 (150.8); 2.6797 (1.0); 2.6750 (2.1); 2.6704 (2.9); 2.6660 (2.1); 2.6614 (1.0); 2.5408 (1.3); 2.5240 (8.9); 2.5193 (13.2); 2.5105 (166.4); 2.5061 (339.8); 2.5015 (448.6); 2.4969 (325.2); 2.4924 (157.9); 2.3375 (0.9); 2.3329 (2.0); 2.3283 (2.8); 2.3238 (2.0); 2.3193 (1.0); 2.0738 (16.0); 1.8308 (1.8); 1.8179 (5.0); 1.8109 (5.6); 1.7997 (2.2); 1.6030 (2.1); 1.5903 (5.4); 1.5835 (5.5); 1.5695 (1.7); 1.3048 (5.7); 1.2863 (13.1); 1.2678 (5.6); 0.0080 (1.0); −0.0001 (36.2); −0.0084 (1.2) I-19 [00026] I-19: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9353 (13.6); 8.8665 (5.1); 8.8625 (5.1); 8.7685 (5.7); 8.7463 (7.8); 8.6174 (7.4); 8.5952 (6.1); 8.4533 (4.0); 8.4314 (6.6); 8.3721 (3.4); 8.3680 (3.3); 8.3503 (2.0); 8.3461 (2.0); 8.3170 (0.8); 8.2491 (4.5); 8.2455 (6.1); 8.2424 (4.7); 7.8852 (0.4); 7.8659 (14.1); 7.8637 (11.6); 3.9064 (1.8); 3.8880 (6.3); 3.8695 (6.4); 3.8511 (1.9); 3.3294 (245.4); 2.6759 (1.8); 2.6714 (2.4); 2.6670 (1.8); 2.5249 (7.0); 2.5112 (149.4); 2.5069 (296.8); 2.5025 (384.4); 2.4979 (281.5); 2.4935 (140.0); 2.3337 (1.7); 2.3293 (2.3); 2.3247 (1.7); 2.0753 (0.7); 1.3079 (7.0); 1.2895 (16.0); 1.2710 (7.0); 0.0080 (1.3); −0.0002 (38.8); −0.0084 (1.7) I-20 [00027] I-20: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9420 (13.2); 8.8661 (5.5); 8.8625 (5.9); 8.7688 (5.2); 8.7466 (7.0); 8.6166 (7.1); 8.5944 (5.7); 8.4528 (4.2); 8.4309 (7.0); 8.3717 (3.7); 8.3678 (3.8); 8.3499 (2.2); 8.3457 (2.3); 8.3170 (0.4); 8.1227 (6.3); 8.1165 (6.7); 8.0198 (5.3); 7.9979 (6.3); 7.7631 (3.5); 7.7569 (3.5); 7.7413 (3.0); 7.7350 (3.1); 3.9061 (2.0); 3.8878 (6.7); 3.8693 (6.8); 3.8510 (2.1); 3.3306 (299.4); 2.6716 (2.0); 2.6676 (1.5); 2.5068 (242.3); 2.5026 (317.1); 2.4983 (246.0); 2.3334 (1.4); 2.3293 (1.9); 2.0753 (1.0); 1.3076 (7.3); 1.2892 (16.0); 1.2707 (7.3); −0.0002 (24.2) I-21 [00028] I-21: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8761 (15.0); 8.7321 (5.7); 8.7099 (7.9); 8.5963 (7.9); 8.5741 (6.3); 8.3164 (1.0); 8.1119 (5.5); 8.0894 (6.1); 8.0723 (4.7); 8.0666 (4.8); 7.8149 (0.9); 7.8075 (7.7); 7.8023 (3.0); 7.7907 (3.3); 7.7852 (11.0); 7.7781 (1.4); 7.6844 (1.4); 7.6770 (10.8); 7.6717 (3.5); 7.6600 (2.8); 7.6547 (7.8); 7.6257 (2.7); 7.6197 (2.6); 7.6033 (2.5); 7.5973 (2.5); 3.8996 (1.9); 3.8813 (6.5); 3.8628 (6.6); 3.8444 (2.0); 3.3280 (332.5); 2.6757 (2.5); 2.6713 (3.4); 2.6667 (2.5); 2.5245 (10.8); 2.5110 (210.6); 2.5068 (415.7); 2.5023 (538.1); 2.4978 (397.9); 2.4936 (200.7); 2.3336 (2.4); 2.3291 (3.3); 2.3246 (2.4); 1.2985 (7.1); 1.2800 (16.0); 1.2615 (6.9); 0.1460 (0.8); 0.0079 (7.5); −0.0002 (182.6); −0.0084 (7.4); −0.1496 (0.8) I-22 [00029] I-22: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8237 (13.4); 8.7301 (5.5); 8.7079 (7.8); 8.5996 (7.4); 8.5774 (5.8); 8.3161 (1.0); 8.1115 (5.3); 8.0892 (5.8); 8.0727 (4.4); 8.0671 (4.6); 7.8063 (0.5); 7.7973 (4.2); 7.7916 (1.7); 7.7852 (4.6); 7.7798 (2.8); 7.7745 (5.1); 7.7625 (4.8); 7.7538 (0.5); 7.6258 (2.6); 7.6198 (2.5); 7.6035 (2.3); 7.5975 (2.4); 7.4664 (4.7); 7.4608 (1.6); 7.4445 (7.7); 7.4279 (1.5); 7.4222 (4.1); 7.4135 (0.4); 3.8982 (1.8); 3.8797 (6.2); 3.8612 (6.3); 3.8428 (1.9); 3.3305 (720.8); 2.6757 (3.0); 2.6712 (4.1); 2.6668 (3.0); 2.5246 (13.0); 2.5110 (271.1); 2.5068 (523.4); 2.5024 (665.4); 2.4978 (479.0); 2.4935 (233.4); 2.3335 (3.1); 2.3291 (4.0); 2.3247 (3.0); 1.2982 (7.0); 1.2797 (16.0); 1.2612 (7.0); 1.2355 (1.0); 0.1462 (1.1); 0.0079 (10.3); −0.0001 (272.5); −0.0084 (10.7); −0.1496 (1.1) I-23 [00030] I-23: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8780 (13.1); 8.7313 (5.6); 8.7090 (7.8); 8.5951 (7.3); 8.5729 (5.8); 8.3162 (2.2); 8.1116 (5.3); 8.0892 (5.9); 8.0717 (4.5); 8.0660 (4.5); 7.8096 (5.9); 7.8042 (2.4); 7.7929 (3.2); 7.7872 (12.1); 7.7810 (1.8); 7.7497 (1.8); 7.7433 (11.7); 7.7377 (3.1); 7.7263 (2.4); 7.7209 (6.2); 7.6251 (2.6); 7.6193 (2.5); 7.6027 (2.3); 7.5969 (2.2); 3.8994 (1.8); 3.8810 (6.1); 3.8625 (6.3); 3.8441 (2.0); 3.3258 (367.2); 2.6754 (5.5); 2.6709 (7.4); 2.6664 (5.5); 2.5243 (23.7); 2.5108 (465.2); 2.5065 (917.4); 2.5020 (1182.0); 2.4974 (855.3); 2.4931 (417.9); 2.3332 (5.2); 2.3288 (7.1); 2.3243 (5.2); 1.2982 (7.0); 1.2797 (16.0); 1.2612 (6.9); 1.2361 (0.4); 0.1457 (2.5); 0.0235 (0.5); 0.0079 (22.5); −0.0002 (597.5); −0.0085 (22.9); −0.0362 (0.4); −0.1496 (2.5) I-24 [00031] I-24: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9212 (13.6); 8.7370 (5.6); 8.7148 (7.9); 8.5981 (7.5); 8.5759 (6.0); 8.3164 (0.6); 8.1137 (5.2); 8.0914 (5.9); 8.0745 (4.5); 8.0689 (4.6); 7.7328 (2.3); 7.7279 (1.6); 7.7122 (1.5); 7.7072 (2.5); 7.7015 (1.7); 7.6756 (1.4); 7.6709 (0.9); 7.6558 (5.5); 7.6507 (3.3); 7.6452 (2.5); 7.6407 (2.5); 7.6258 (4.2); 7.6216 (3.4); 7.6053 (3.3); 7.5992 (2.4); 7.3417 (1.0); 7.3359 (1.6); 7.3290 (0.9); 7.3238 (1.1); 7.3186 (2.3); 7.3127 (1.6); 7.3001 (1.0); 7.2968 (1.2); 7.2905 (0.8); 3.9020 (1.8); 3.8834 (6.2); 3.8649 (6.3); 3.8465 (1.9); 3.3308 (317.7); 2.6759 (1.6); 2.6714 (2.1); 2.6668 (1.6); 2.5248 (6.6); 2.5113 (133.6); 2.5070 (264.6); 2.5025 (342.2); 2.4979 (248.8); 2.4936 (122.5); 2.3338 (1.5); 2.3293 (2.0); 2.3248 (1.5); 2.0749 (5.9); 1.3001 (7.0); 1.2888 (2.9); 1.2817 (16.0); 1.2632 (6.8); 0.0080 (1.5); −0.0002 (40.5); −0.0084 (1.6) I-25 [00032] I-25: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9216 (14.5); 8.7365 (5.8); 8.7143 (7.9); 8.5939 (7.8); 8.5717 (6.2); 8.3163 (1.0); 8.1135 (5.5); 8.0911 (6.2); 8.0733 (4.6); 8.0675 (4.6); 7.9257 (3.5); 7.9207 (6.6); 7.9157 (3.6); 7.7879 (2.0); 7.7857 (2.4); 7.7831 (2.1); 7.7807 (2.0); 7.7679 (2.6); 7.7654 (2.8); 7.7629 (2.8); 7.7604 (2.4); 7.6375 (2.9); 7.6271 (2.8); 7.6174 (6.6); 7.6049 (2.6); 7.5974 (5.2); 7.5441 (2.9); 7.5417 (3.2); 7.5392 (3.2); 7.5369 (2.8); 7.5240 (1.8); 7.5215 (2.0); 7.5191 (2.0); 7.5167 (1.7); 3.9025 (1.8); 3.8841 (6.3); 3.8656 (6.4); 3.8472 (1.9); 3.3267 (238.4); 2.6757 (2.4); 2.6711 (3.2); 2.6666 (2.4); 2.5245 (10.4); 2.5110 (207.3); 2.5067 (410.9); 2.5022 (530.3); 2.4976 (383.2); 2.4932 (186.9); 2.3377 (1.1); 2.3335 (2.3); 2.3290 (3.2); 2.3245 (2.3); 2.0747 (4.4); 1.3004 (7.0); 1.2819 (16.0); 1.2634 (6.9); 0.1461 (0.4); 0.0079 (3.5); −0.0002 (97.2); −0.0084 (3.6); −0.1495 (0.4) I-26 [00033] I-26: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9161 (13.6); 8.7354 (5.6); 8.7132 (7.8); 8.5922 (7.5); 8.5700 (6.0); 8.3170 (0.6); 8.1141 (5.4); 8.0917 (6.0); 8.0744 (4.6); 8.0687 (4.7); 8.0489 (3.5); 8.0441 (6.6); 8.0392 (3.6); 7.8204 (2.5); 7.8176 (2.2); 7.8155 (2.1); 7.8002 (2.8); 7.7973 (2.7); 7.6741 (2.3); 7.6719 (2.2); 7.6696 (2.0); 7.6539 (3.2); 7.6518 (3.2); 7.6496 (2.7); 7.6277 (2.6); 7.6217 (2.6); 7.6053 (2.4); 7.5993 (2.4); 7.5677 (3.8); 7.5475 (5.8); 7.5273 (2.5); 3.9024 (1.8); 3.8839 (6.3); 3.8654 (6.4); 3.8470 (1.9); 3.3273 (202.5); 2.6756 (2.0); 2.6711 (2.8); 2.6667 (2.1); 2.5245 (8.7); 2.5109 (174.6); 2.5066 (345.6); 2.5022 (446.1); 2.4976 (324.2); 2.4933 (159.7); 2.3334 (2.0); 2.3290 (2.7); 2.3245 (2.0); 2.0751 (0.3); 1.9890 (0.5); 1.2998 (7.1); 1.2814 (16.0); 1.2628 (7.0); 1.2338 (0.4); 0.1459 (1.0); 0.0079 (8.7); −0.0002 (243.2); −0.0084 (9.5); −0.1496 (1.0) I-27 [00034] I-27: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9520 (15.2); 8.8749 (5.0); 8.8706 (4.9); 8.7822 (6.0); 8.7600 (8.0); 8.6152 (7.8); 8.5930 (6.8); 8.4571 (3.8); 8.4351 (6.6); 8.4223 (6.3); 8.4157 (6.4); 8.3784 (3.3); 8.3740 (3.1); 8.3567 (1.9); 8.3522 (2.0); 8.2159 (3.3); 8.2093 (2.9); 8.1937 (4.0); 8.1871 (3.9); 8.0199 (6.5); 7.9977 (5.4); 3.9125 (1.8); 3.8941 (6.3); 3.8756 (6.4); 3.8571 (1.8); 3.4056 (0.3); 3.3412 (748.4); 2.6841 (0.7); 2.6799 (1.4); 2.6753 (1.9); 2.6708 (1.4); 2.6664 (0.6); 2.5287 (6.7); 2.5153 (123.6); 2.5109 (244.6); 2.5064 (315.0); 2.5018 (223.5); 2.4973 (105.7); 2.3377 (1.4); 2.3331 (1.8); 2.3286 (1.3); 2.3243 (0.6); 1.3122 (7.0); 1.2937 (16.0); 1.2753 (6.8) I-28 [00035] I-28: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 9.0643 (13.2); 8.8732 (4.8); 8.8689 (4.8); 8.7823 (6.1); 8.7601 (8.0); 8.6085 (7.7); 8.5863 (6.8); 8.4567 (3.9); 8.4347 (6.5); 8.3762 (3.3); 8.3719 (3.1); 8.3543 (1.9); 8.3501 (1.9); 8.3186 (1.6); 8.2813 (6.6); 8.2763 (6.6); 8.2459 (5.2); 8.2244 (6.5); 8.0767 (4.1); 8.0715 (3.8); 8.0552 (3.2); 8.0500 (3.2); 3.9123 (1.8); 3.8939 (6.1); 3.8753 (6.2); 3.8571 (1.9); 3.4640 (0.4); 3.3381 (1142.8); 2.6808 (2.2); 2.6764 (4.5); 2.6718 (6.2); 2.6672 (4.5); 2.6626 (2.1); 2.6421 (0.3); 2.6222 (0.4); 2.5252 (20.2); 2.5118 (376.3); 2.5073 (745.0); 2.5028 (980.1); 2.4982 (732.1); 2.4938 (361.4); 2.4239 (0.4); 2.3386 (2.1); 2.3342 (4.4); 2.3296 (6.0); 2.3251 (4.3); 1.3088 (6.9); 1.2904 (16.0); 1.2719 (6.8); 1.2372 (0.4); 0.1460 (3.0); 0.0288 (0.4); 0.0266 (0.4); 0.0243 (0.5); 0.0192 (1.0); 0.0080 (29.4); −0.0002 (782.4); −0.0085 (29.3); −0.0434 (0.4); −0.1495 (3.1) I-29 [00036] I-29: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 9.0098 (15.0); 8.7445 (5.9); 8.7224 (8.1); 8.6071 (0.3); 8.5897 (8.2); 8.5675 (6.7); 8.3160 (1.6); 8.1697 (0.5); 8.1132 (5.6); 8.1056 (5.7); 8.1004 (2.7); 8.0907 (7.3); 8.0832 (11.9); 8.0747 (4.8); 8.0686 (4.6); 8.0422 (11.5); 8.0369 (3.3); 8.0252 (2.4); 8.0199 (5.8); 7.9521 (0.3); 7.9310 (0.4); 7.6278 (2.6); 7.6217 (2.5); 7.6056 (2.4); 7.5994 (2.4); 7.5392 (0.4); 7.5256 (0.3); 7.4208 (0.4); 7.3125 (0.3); 6.9265 (0.4); 6.5431 (0.3); 5.5951 (0.4); 3.9033 (1.8); 3.8850 (6.2); 3.8664 (6.3); 3.8478 (1.8); 3.7962 (0.7); 3.4025 (0.5); 3.3703 (2.1); 3.3289 (982.8); 2.6758 (3.6); 2.6712 (4.8); 2.6667 (3.6); 2.6239 (1.6); 2.6031 (0.4); 2.5246 (15.9); 2.5112 (302.2); 2.5068 (597.3); 2.5022 (779.4); 2.4976 (574.6); 2.4932 (284.0); 2.4348 (0.5); 2.3336 (3.5); 2.3290 (4.7); 2.3245 (3.5); 1.6689 (0.4); 1.6524 (0.5); 1.3002 (7.0); 1.2818 (16.0); 1.2633 (6.8); 1.1916 (0.6); 0.1460 (3.9); 0.0080 (40.5); −0.0001 (955.4); −0.0084 (42.0); −0.0260 (1.5); −0.1496 (4.0) I-30 [00037] I-30: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9478 (12.4); 8.7454 (5.6); 8.7232 (7.4); 8.5919 (7.2); 8.5698 (5.8); 8.3161 (3.3); 8.2757 (5.2); 8.1740 (2.7); 8.1532 (2.7); 8.1503 (2.5); 8.1149 (5.0); 8.0926 (5.6); 8.0755 (4.4); 8.0700 (4.5); 7.9464 (3.0); 7.9271 (3.8); 7.8290 (3.3); 7.8088 (4.7); 7.7890 (2.2); 7.6794 (0.5); 7.6291 (2.8); 7.6234 (2.6); 7.6069 (2.4); 7.6007 (2.5); 3.9048 (2.0); 3.8867 (6.1); 3.8683 (6.2); 3.8498 (2.0); 3.4804 (0.4); 3.4589 (0.5); 3.3252 (1007.7); 2.9430 (0.4); 2.7669 (0.4); 2.7380 (0.5); 2.6753 (9.1); 2.6707 (12.0); 2.6662 (9.2); 2.5106 (761.6); 2.5063 (1469.4); 2.5018 (1909.0); 2.4973 (1423.1); 2.4932 (731.4); 2.3331 (8.7); 2.3287 (11.8); 2.3243 (8.8); 1.3016 (7.2); 1.2831 (16.0); 1.2646 (7.0); 1.2358 (0.6); 1.2040 (0.5); 0.1458 (6.8); 0.0078 (75.7); −0.0003 (1623.2); −0.0086 (77.3); −0.0874 (0.6); −0.1497 (7.2) I-31 [00038] I-31: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8977 (14.2); 8.7280 (5.3); 8.7058 (7.8); 8.6132 (7.8); 8.5910 (5.8); 8.3154 (0.8); 8.1142 (5.5); 8.0918 (6.1); 8.0709 (4.5); 8.0652 (4.6); 7.7106 (2.2); 7.6907 (3.7); 7.6803 (4.0); 7.6759 (5.7); 7.6714 (2.8); 7.6248 (2.8); 7.6189 (5.3); 7.5992 (6.6); 7.5794 (2.6); 7.4560 (3.1); 7.4364 (2.4); 3.8973 (1.9); 3.8790 (6.5); 3.8605 (6.6); 3.8419 (2.0); 3.3223 (167.0); 2.6752 (1.8); 2.6709 (2.4); 2.6664 (1.8); 2.5106 (154.1); 2.5064 (295.4); 2.5019 (377.8); 2.4974 (270.3); 2.4932 (130.8); 2.3332 (1.8); 2.3288 (2.4); 2.3243 (1.7); 2.0740 (3.6); 1.8530 (2.3); 1.8400 (7.3); 1.8328 (7.4); 1.8212 (3.0); 1.6689 (0.3); 1.6308 (3.0); 1.6185 (7.2); 1.6115 (7.4); 1.5981 (2.2); 1.3001 (7.2); 1.2816 (16.0); 1.2632 (6.9); 0.1459 (3.0); 0.0079 (31.7); −0.0002 (630.0); −0.0085 (25.4); −0.1496 (3.0) I-32 [00039] I-32: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.6757 (5.6); 8.6535 (8.2); 8.5591 (8.4); 8.5369 (6.2); 8.4096 (0.4); 8.3461 (14.6); 8.3186 (0.4); 8.0885 (5.5); 8.0658 (8.9); 7.6359 (2.2); 7.6320 (2.0); 7.6136 (1.9); 7.6094 (1.9); 4.0197 (0.4); 3.8676 (2.0); 3.8492 (6.6); 3.8306 (6.6); 3.8119 (2.0); 3.3299 (755.6); 3.0996 (0.8); 3.0886 (1.2); 3.0835 (1.4); 3.0725 (2.8); 3.0642 (1.5); 3.0568 (1.3); 3.0451 (0.8); 2.6753 (5.1); 2.6709 (6.7); 2.6665 (4.9); 2.6619 (2.4); 2.5243 (26.0); 2.5108 (422.0); 2.5065 (812.4); 2.5019 (1043.6); 2.4974 (760.5); 2.4930 (370.0); 2.3333 (4.7); 2.3288 (6.4); 2.3243 (4.6); 1.9892 (1.2); 1.7593 (0.6); 1.3975 (1.4); 1.2974 (0.4); 1.2774 (7.0); 1.2589 (16.0); 1.2404 (7.0); 1.1916 (0.4); 1.1841 (0.4); 1.1743 (0.8); 1.1566 (0.4); 0.9877 (0.7); 0.9680 (7.8); 0.9649 (8.8); 0.9617 (9.3); 0.9492 (3.6); 0.9456 (4.8); 0.9398 (3.1); 0.9181 (0.4); 0.1458 (1.5); 0.0079 (14.9); −0.0002 (376.6); −0.0085 (13.2); −0.1496 (1.6) I-33 [00040] I-33: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8234 (16.0); 8.7284 (5.6); 8.7062 (7.9); 8.5980 (8.0); 8.5758 (6.4); 8.1054 (5.1); 8.0827 (8.1); 8.0761 (3.5); 7.8055 (0.4); 7.7966 (3.9); 7.7909 (1.4); 7.7845 (4.2); 7.7792 (2.4); 7.7738 (4.8); 7.7675 (1.6); 7.7617 (4.4); 7.7529 (0.4); 7.6478 (1.9); 7.6437 (1.7); 7.6254 (1.7); 7.6212 (1.7); 7.4776 (0.5); 7.4686 (4.6); 7.4629 (1.4); 7.4466 (7.2); 7.4415 (1.6); 7.4300 (1.4); 7.4243 (4.0); 3.8960 (1.7); 3.8774 (5.8); 3.8589 (6.0); 3.8405 (1.7); 3.3319 (687.9); 3.2981 (0.4); 2.6800 (1.4); 2.6757 (3.0); 2.6711 (4.2); 2.6665 (3.0); 2.6620 (1.4); 2.5879 (0.4); 2.5246 (14.2); 2.5199 (21.0); 2.5112 (250.6); 2.5067 (499.0); 2.5021 (651.3); 2.4975 (470.9); 2.4930 (224.8); 2.3381 (1.3); 2.3336 (2.9); 2.3290 (4.0); 2.3244 (2.9); 2.3201 (1.3); 1.3974 (15.5); 1.2947 (6.3); 1.2763 (14.6); 1.2578 (6.4); 1.2347 (1.0); −0.0001 (11.5); −0.0084 (0.3) I-34 [00041] I-34: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8243 (12.3); 8.7274 (4.1); 8.7051 (5.9); 8.5949 (5.9); 8.5727 (4.8); 8.0702 (3.8); 8.0478 (4.1); 7.9288 (2.9); 7.9230 (3.0); 7.7976 (2.9); 7.7920 (1.0); 7.7855 (3.1); 7.7802 (1.8); 7.7748 (3.5); 7.7684 (1.1); 7.7627 (3.3); 7.5335 (1.7); 7.5275 (1.6); 7.5113 (1.6); 7.5052 (1.6); 7.4683 (3.4); 7.4627 (1.0); 7.4557 (0.5); 7.4510 (1.2); 7.4464 (5.4); 7.4413 (1.1); 7.4369 (0.4); 7.4298 (1.0); 7.4241 (3.0); 7.0190 (0.4); 7.0114 (0.6); 6.8887 (0.7); 6.8816 (1.5); 6.8738 (0.7); 6.7523 (0.7); 6.7443 (0.4); 3.9024 (1.2); 3.8840 (4.2); 3.8655 (4.3); 3.8470 (1.2); 3.3293 (158.7); 2.6800 (0.6); 2.6756 (1.4); 2.6710 (2.0); 2.6664 (1.4); 2.6620 (0.7); 2.5246 (6.3); 2.5198 (9.4); 2.5111 (114.9); 2.5066 (232.1); 2.5020 (305.1); 2.4974 (221.6); 2.4929 (105.9); 2.3380 (0.6); 2.3335 (1.4); 2.3289 (1.9); 2.3244 (1.4); 2.3200 (0.6); 1.9893 (0.7); 1.3974 (16.0); 1.2970 (4.7); 1.2785 (10.7); 1.2600 (4.6); 1.2349 (0.4); 1.1745 (0.4); −0.0001 (5.4) I-35 [00042] I-35: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 9.5200 (7.2); 8.8315 (15.8); 8.7688 (5.7); 8.7466 (8.4); 8.6893 (7.7); 8.6874 (7.7); 8.6516 (8.2); 8.6293 (6.2); 8.3553 (1.4); 7.8054 (0.4); 7.7967 (4.1); 7.7912 (1.5); 7.7846 (4.5); 7.7793 (2.6); 7.7739 (5.1); 7.7674 (1.7); 7.7619 (4.7); 7.7529 (0.4); 7.7341 (0.7); 7.7219 (0.8); 7.7166 (0.4); 7.7113 (0.8); 7.6991 (0.8); 7.4791 (0.5); 7.4702 (4.9); 7.4646 (1.5); 7.4575 (0.7); 7.4528 (1.8); 7.4482 (7.8); 7.4433 (1.7); 7.4317 (1.4); 7.4260 (4.3); 7.4172 (0.4); 7.3794 (0.8); 7.3573 (1.3); 7.3350 (0.7); 4.0554 (0.4); 4.0376 (1.0); 4.0197 (1.0); 4.0020 (0.4); 3.8502 (1.8); 3.8318 (6.4); 3.8132 (6.5); 3.7948 (1.9); 3.3352 (435.2); 2.6761 (1.6); 2.6715 (2.1); 2.6670 (1.5); 2.6626 (0.7); 2.5250 (7.4); 2.5203 (10.9); 2.5116 (129.5); 2.5071 (257.5); 2.5026 (335.9); 2.4980 (244.4); 2.4935 (117.8); 2.3385 (0.6); 2.3339 (1.4); 2.3294 (2.0); 2.3249 (1.4); 2.3205 (0.6); 1.9894 (4.6); 1.3974 (4.6); 1.3000 (7.1); 1.2816 (16.0); 1.2630 (6.8); 1.2349 (0.5); 1.1924 (1.3); 1.1746 (2.5); 1.1568 (1.3); 0.8711 (0.3); 0.8525 (0.4); −0.0002 (2.6) I-36 [00043] I-36: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8254 (15.9); 8.7381 (6.0); 8.7159 (8.6); 8.6096 (8.4); 8.5874 (6.7); 8.4340 (4.4); 8.2078 (3.3); 8.1862 (4.1); 7.9916 (2.6); 7.9876 (2.5); 7.9698 (2.2); 7.9657 (2.0); 7.8061 (0.4); 7.7974 (4.2); 7.7918 (1.6); 7.7853 (4.6); 7.7800 (2.6); 7.7746 (5.2); 7.7682 (1.6); 7.7625 (4.8); 7.7537 (0.4); 7.4782 (0.5); 7.4694 (5.0); 7.4637 (1.5); 7.4522 (1.8); 7.4474 (7.7); 7.4423 (1.6); 7.4376 (0.6); 7.4308 (1.3); 7.4252 (4.3); 7.4162 (0.3); 4.0374 (0.5); 4.0194 (0.6); 3.8966 (1.8); 3.8783 (6.2); 3.8597 (6.4); 3.8413 (1.8); 3.3992 (0.4); 3.3721 (0.9); 3.3341 (721.4); 2.6801 (1.2); 2.6758 (2.6); 2.6712 (3.7); 2.6666 (2.6); 2.6620 (1.2); 2.5247 (12.7); 2.5200 (19.2); 2.5113 (217.8); 2.5068 (435.0); 2.5022 (568.6); 2.4976 (411.4); 2.4931 (195.6); 2.4456 (0.4); 2.3382 (1.2); 2.3336 (2.6); 2.3290 (3.5); 2.3245 (2.5); 2.3199 (1.1); 1.9893 (2.2); 1.3973 (1.7); 1.3007 (6.9); 1.2823 (16.0); 1.2638 (6.7); 1.2346 (0.4); 1.1921 (0.6); 1.1744 (1.2); 1.1565 (0.6); −0.0002 (8.9) I-37 [00044] I-37: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.6821 (5.6); 8.6599 (8.6); 8.5812 (8.7); 8.5590 (6.2); 8.4973 (13.8); 8.1060 (5.7); 8.0835 (6.3); 8.0698 (4.8); 8.0640 (4.7); 7.6240 (2.7); 7.6179 (2.6); 7.6017 (2.5); 7.5956 (2.4); 4.4001 (0.4); 4.3817 (1.2); 4.3640 (1.7); 4.3462 (1.2); 4.3278 (0.4); 3.8771 (1.9); 3.8587 (6.6); 3.8402 (6.7); 3.8217 (2.0); 3.3355 (83.9); 2.6811 (1.1); 2.6766 (1.5); 2.6722 (1.1); 2.5300 (5.5); 2.5164 (96.3); 2.5121 (181.8); 2.5076 (230.7); 2.5031 (167.1); 2.4987 (80.0); 2.3431 (0.6); 2.3389 (1.1); 2.3345 (1.4); 2.3299 (1.0); 2.0977 (0.8); 2.0902 (0.9); 2.0815 (1.5); 2.0696 (2.2); 2.0501 (2.4); 2.0360 (1.2); 2.0299 (1.3); 1.8656 (0.5); 1.8497 (1.6); 1.8319 (2.6); 1.8149 (6.2); 1.8065 (4.7); 1.7847 (1.4); 1.7772 (1.1); 1.6938 (0.6); 1.6849 (0.6); 1.6778 (0.9); 1.6508 (2.7); 1.6398 (1.9); 1.2859 (7.1); 1.2675 (16.0); 1.2489 (6.9) I-38 [00045] I-38: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.6879 (5.4); 8.6657 (8.5); 8.5891 (8.5); 8.5669 (6.0); 8.4939 (12.9); 8.3809 (4.7); 8.3782 (4.6); 8.2274 (3.6); 8.2056 (4.3); 7.9307 (2.5); 7.9271 (2.5); 7.9087 (2.2); 7.9053 (2.1); 4.3965 (0.4); 4.3774 (1.1); 4.3603 (1.6); 4.3422 (1.2); 4.3245 (0.4); 3.8778 (1.8); 3.8595 (6.4); 3.8409 (6.5); 3.8225 (1.9); 3.3307 (261.4); 2.6759 (1.9); 2.6714 (2.6); 2.6668 (1.9); 2.6623 (0.9); 2.5248 (9.0); 2.5201 (13.8); 2.5113 (165.0); 2.5069 (325.7); 2.5024 (417.0); 2.4978 (295.8); 2.4934 (139.5); 2.3337 (1.9); 2.3292 (2.5); 2.3246 (1.8); 2.0936 (0.8); 2.0864 (0.9); 2.0759 (1.9); 2.0655 (2.0); 2.0460 (2.2); 2.0324 (1.1); 2.0258 (1.2); 1.8613 (0.5); 1.8452 (1.4); 1.8270 (2.4); 1.8101 (5.8); 1.8015 (4.4); 1.7798 (1.4); 1.6884 (0.5); 1.6817 (0.6); 1.6734 (0.9); 1.6467 (2.5); 1.6357 (1.8); 1.2843 (7.0); 1.2658 (16.0); 1.2474 (6.8); 0.1462 (0.6); 0.0080 (4.5); −0.0002 (136.3); −0.0085 (4.3); −0.1495 (0.6) I-39 [00046] I-39: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8563 (5.1); 8.8523 (5.0); 8.7197 (5.6); 8.6974 (7.8); 8.5854 (7.7); 8.5631 (6.0); 8.4403 (4.0); 8.4185 (7.0); 8.4064 (13.1); 8.3649 (3.5); 8.3607 (3.3); 8.3432 (2.0); 8.3387 (2.0); 3.8828 (1.9); 3.8643 (6.4); 3.8458 (6.6); 3.8274 (2.0); 3.5396 (1.3); 3.5283 (1.8); 3.5194 (2.6); 3.5104 (1.9); 3.4989 (1.4); 3.3335 (402.2); 2.6756 (2.8); 2.6712 (4.1); 2.6668 (3.0); 2.6622 (1.9); 2.6521 (1.1); 2.6444 (1.4); 2.6359 (1.3); 2.6269 (1.6); 2.6184 (1.1); 2.6093 (1.0); 2.6011 (0.8); 2.5922 (0.5); 2.5838 (0.6); 2.5246 (13.1); 2.5110 (223.0); 2.5068 (428.8); 2.5023 (552.5); 2.4978 (407.5); 2.4935 (200.5); 2.3336 (2.5); 2.3292 (3.4); 2.3246 (2.4); 2.1173 (0.4); 2.0862 (0.4); 1.7339 (0.8); 1.7177 (1.3); 1.7064 (1.5); 1.6961 (1.2); 1.6797 (0.9); 1.5295 (1.1); 1.5124 (2.4); 1.4920 (2.4); 1.4751 (1.0); 1.2918 (7.2); 1.2733 (16.0); 1.2549 (7.0); 1.2349 (0.6); 1.1394 (0.9); 0.8752 (0.4); −0.0002 (4.7) I-40 [00047] I-40: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9857 (16.0); 8.9452 (3.3); 8.9418 (4.4); 8.9383 (3.2); 8.8741 (4.4); 8.8696 (4.4); 8.7808 (5.8); 8.7586 (7.8); 8.7125 (5.3); 8.7060 (5.4); 8.6203 (7.8); 8.5981 (6.6); 8.4564 (3.6); 8.4347 (6.1); 8.4339 (6.0); 8.3764 (3.0); 8.3719 (2.8); 8.3545 (1.8); 8.3500 (1.8); 8.2729 (1.9); 8.2669 (2.6); 8.2613 (1.7); 8.2479 (1.9); 8.2424 (2.6); 8.2362 (1.7); 4.0553 (0.8); 4.0375 (2.3); 4.0197 (2.3); 4.0019 (0.8); 3.9108 (1.7); 3.8923 (6.0); 3.8738 (6.1); 3.8554 (1.8); 3.3330 (308.6); 2.7641 (0.8); 2.7520 (0.8); 2.6805 (0.6); 2.6760 (1.2); 2.6715 (1.7); 2.6670 (1.2); 2.6623 (0.6); 2.5250 (5.6); 2.5202 (8.6); 2.5115 (101.4); 2.5071 (201.3); 2.5025 (260.8); 2.4979 (187.7); 2.4934 (89.3); 2.3384 (0.6); 2.3338 (1.2); 2.3293 (1.7); 2.3248 (1.2); 2.3203 (0.5); 2.0122 (0.9); 1.9895 (10.3); 1.3972 (0.7); 1.3098 (6.5); 1.2913 (15.2); 1.2728 (6.4); 1.2584 (0.5); 1.2346 (0.4); 1.1923 (2.8); 1.1745 (5.6); 1.1567 (2.8); 0.8878 (1.0); 0.8710 (1.0); −0.0002 (3.9) I-41 [00048] I-41: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9289 (14.9); 8.8663 (5.4); 8.8620 (5.4); 8.7690 (5.6); 8.7468 (7.8); 8.6291 (7.8); 8.6069 (6.2); 8.4593 (4.4); 8.4374 (6.9); 8.3700 (3.5); 8.3655 (3.4); 8.3482 (2.2); 8.3435 (2.2); 7.9256 (3.4); 7.9205 (6.5); 7.9156 (3.6); 7.7863 (2.4); 7.7838 (2.2); 7.7814 (2.0); 7.7661 (2.9); 7.7634 (2.9); 7.7612 (2.6); 7.6396 (2.8); 7.6194 (5.9); 7.5992 (3.5); 7.5449 (3.3); 7.5424 (3.3); 7.5401 (3.0); 7.5247 (2.0); 7.5222 (2.1); 7.5199 (1.8); 5.7600 (13.9); 3.9083 (1.9); 3.8900 (6.6); 3.8715 (6.7); 3.8530 (2.0); 3.3313 (129.0); 2.6762 (0.9); 2.6717 (1.2); 2.6671 (0.9); 2.5248 (4.2); 2.5071 (147.2); 2.5026 (192.0); 2.4982 (142.2); 2.3339 (0.9); 2.3295 (1.2); 2.3250 (0.9); 1.3080 (7.2); 1.2896 (16.0); 1.2711 (7.0); −0.0002 (7.4) I-42 [00049] I-42: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9293 (14.3); 8.8663 (4.7); 8.8618 (4.4); 8.7695 (5.1); 8.7472 (7.2); 8.6337 (7.3); 8.6115 (5.8); 8.4596 (3.6); 8.4378 (5.7); 8.3701 (3.1); 8.3655 (2.8); 8.3482 (1.9); 8.3435 (1.8); 7.7364 (1.6); 7.7333 (2.0); 7.7284 (1.4); 7.7126 (1.3); 7.7078 (2.2); 7.7023 (1.5); 7.6798 (0.6); 7.6765 (1.1); 7.6718 (0.7); 7.6591 (4.5); 7.6563 (4.2); 7.6515 (2.7); 7.6474 (2.2); 7.6429 (2.1); 7.6276 (2.0); 7.6228 (0.6); 7.6073 (0.8); 7.3449 (0.9); 7.3389 (1.4); 7.3316 (0.8); 7.3273 (0.9); 7.3222 (2.0); 7.3162 (1.3); 7.3034 (0.9); 7.2999 (1.0); 7.2976 (0.8); 7.2937 (0.7); 5.7599 (16.0); 3.9081 (1.6); 3.8896 (5.7); 3.8711 (5.8); 3.8527 (1.7); 3.3321 (126.4); 2.6765 (0.7); 2.6720 (0.9); 2.6674 (0.7); 2.5254 (3.5); 2.5119 (61.3); 2.5075 (115.9); 2.5030 (145.6); 2.4984 (103.5); 2.4940 (48.9); 2.3343 (0.7); 2.3298 (0.9); 2.3253 (0.7); 1.3083 (6.2); 1.2899 (14.1); 1.2714 (6.0); −0.0001 (6.7) I-43 [00050] I-43: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8700 (2.3); 8.8659 (2.2); 8.7843 (5.8); 8.7597 (2.2); 8.7375 (3.0); 8.6259 (3.0); 8.6037 (2.3); 8.5042 (2.2); 8.4976 (2.1); 8.4527 (1.7); 8.4308 (2.8); 8.3730 (1.6); 8.3689 (1.5); 8.3511 (0.9); 8.3468 (0.9); 8.0548 (1.4); 8.0480 (1.3); 8.0326 (1.4); 8.0257 (1.4); 7.0598 (2.2); 7.0375 (2.1); 3.9150 (16.0); 3.9006 (0.9); 3.8821 (2.8); 3.8636 (2.7); 3.8453 (0.8); 3.3319 (158.1); 2.6755 (1.0); 2.6712 (1.3); 2.6668 (1.0); 2.5242 (6.0); 2.5066 (163.5); 2.5022 (206.0); 2.4978 (151.9); 2.3334 (1.0); 2.3290 (1.3); 2.3246 (1.0); 2.0862 (2.1); 1.3046 (2.9); 1.2861 (6.3); 1.2676 (2.8); 1.1394 (0.4); 0.0077 (1.0); −0.0002 (20.9); −0.0084 (0.9) I-44 [00051] I-44: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9180 (15.9); 8.7471 (6.1); 8.7249 (8.5); 8.6051 (8.2); 8.5829 (6.7); 8.3969 (4.4); 8.3936 (4.4); 8.2426 (3.5); 8.2209 (4.2); 8.0490 (3.4); 8.0441 (6.4); 8.0392 (3.5); 7.9426 (2.4); 7.9388 (2.4); 7.9208 (2.1); 7.9170 (2.1); 7.8228 (2.0); 7.8205 (2.3); 7.8177 (2.0); 7.8154 (2.0); 7.8025 (2.4); 7.8002 (2.5); 7.7974 (2.5); 7.7951 (2.2); 7.6787 (1.9); 7.6764 (2.2); 7.6740 (2.0); 7.6717 (1.8); 7.6585 (2.7); 7.6562 (2.9); 7.6539 (2.9); 7.6515 (2.5); 7.5694 (3.9); 7.5491 (5.9); 7.5289 (2.5); 3.9094 (1.7); 3.8909 (6.2); 3.8724 (6.3); 3.8539 (1.8); 3.3302 (302.6); 2.6800 (1.0); 2.6756 (2.1); 2.6711 (3.0); 2.6665 (2.2); 2.6620 (1.0); 2.5247 (9.7); 2.5199 (14.3); 2.5112 (174.6); 2.5067 (351.4); 2.5022 (457.0); 2.4975 (328.0); 2.4930 (156.3); 2.3381 (1.0); 2.3336 (2.1); 2.3290 (2.9); 2.3244 (2.0); 2.3199 (0.9); 2.0758 (1.2); 1.3025 (6.8); 1.2840 (16.0); 1.2655 (6.6); 0.0080 (0.8); −0.0001 (25.7); −0.0084 (0.8) I-45 [00052] I-45: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8786 (15.5); 8.7440 (5.8); 8.7217 (8.2); 8.6088 (8.0); 8.5866 (6.3); 8.3955 (4.6); 8.3927 (4.7); 8.2404 (3.7); 8.2187 (4.4); 7.9412 (2.5); 7.9372 (2.5); 7.9193 (2.2); 7.9155 (2.3); 7.8147 (0.7); 7.8073 (7.6); 7.8021 (2.6); 7.7906 (3.0); 7.7851 (11.1); 7.7777 (1.2); 7.6875 (1.2); 7.6801 (10.9); 7.6747 (3.0); 7.6632 (2.6); 7.6579 (7.9); 7.6505 (0.6); 3.9064 (1.8); 3.8880 (6.4); 3.8695 (6.5); 3.8512 (1.8); 3.3304 (419.7); 2.8906 (0.7); 2.7312 (0.6); 2.6798 (1.4); 2.6755 (2.8); 2.6710 (3.9); 2.6665 (2.8); 2.6620 (1.3); 2.5245 (12.6); 2.5197 (19.0); 2.5110 (233.7); 2.5066 (467.7); 2.5020 (609.6); 2.4974 (441.5); 2.4930 (214.2); 2.3377 (1.3); 2.3333 (2.7); 2.3288 (3.8); 2.3243 (2.7); 2.3198 (1.3); 1.3007 (7.0); 1.2822 (16.0); 1.2637 (6.8); 1.2336 (0.5); 0.0080 (0.8); −0.0001 (25.8); −0.0084 (0.9) I-46 [00053] I-46: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9230 (13.9); 8.9153 (1.1); 8.7481 (5.4); 8.7260 (7.4); 8.6061 (7.4); 8.5839 (5.7); 8.3934 (5.7); 8.2418 (4.2); 8.2200 (5.0); 7.9387 (3.2); 7.9253 (4.3); 7.9206 (9.2); 7.9160 (6.4); 7.7863 (2.6); 7.7662 (3.1); 7.7637 (3.1); 7.6392 (2.8); 7.6190 (5.9); 7.5988 (3.5); 7.5427 (3.4); 7.5250 (2.2); 7.5224 (2.2); 7.2509 (0.4); 7.2324 (0.4); 7.1830 (0.4); 7.1625 (0.4); 3.9088 (2.1); 3.8905 (6.9); 3.8720 (7.1); 3.8536 (2.2); 3.3286 (315.1); 3.3206 (27.8); 2.6753 (2.1); 2.6707 (2.8); 2.6667 (2.2); 2.5062 (353.9); 2.5020 (455.2); 2.4977 (349.8); 2.3330 (2.1); 2.3288 (2.8); 2.3246 (2.2); 2.2997 (1.8); 1.3026 (7.3); 1.2841 (16.0); 1.2657 (7.3); −0.0003 (24.4); −0.0080 (2.4) I-47 [00054] I-47: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9224 (15.9); 8.7484 (5.9); 8.7262 (8.2); 8.6104 (8.3); 8.5882 (6.6); 8.3962 (4.7); 8.3928 (4.6); 8.2415 (3.7); 8.2200 (4.4); 7.9422 (2.5); 7.9385 (2.5); 7.9206 (2.2); 7.9164 (2.2); 7.7359 (1.8); 7.7327 (2.2); 7.7276 (1.6); 7.7121 (1.5); 7.7070 (2.4); 7.7016 (1.7); 7.6789 (0.6); 7.6756 (1.2); 7.6708 (0.9); 7.6583 (5.0); 7.6555 (4.8); 7.6507 (3.1); 7.6466 (2.5); 7.6422 (2.3); 7.6268 (2.3); 7.6066 (0.8); 7.3442 (1.0); 7.3382 (1.6); 7.3309 (0.9); 7.3268 (1.0); 7.3215 (2.2); 7.3156 (1.4); 7.3028 (1.0); 7.2992 (1.1); 7.2970 (0.9); 7.2930 (0.8); 3.9078 (1.8); 3.8895 (6.4); 3.8709 (6.6); 3.8525 (1.9); 3.3298 (641.7); 2.6797 (1.3); 2.6754 (2.6); 2.6708 (3.6); 2.6663 (2.6); 2.6617 (1.2); 2.5242 (13.4); 2.5109 (228.4); 2.5064 (439.0); 2.5019 (558.2); 2.4973 (398.3); 2.4928 (188.8); 2.3379 (1.3); 2.3332 (2.6); 2.3288 (3.5); 2.3242 (2.5); 2.3198 (1.2); 2.0750 (0.3); 1.3024 (7.0); 1.2840 (16.0); 1.2655 (6.8); 0.0076 (2.4); −0.0004 (56.2); −0.0085 (1.7) I-48 [00055] I-48: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8796 (16.0); 8.7428 (5.5); 8.7206 (7.7); 8.6068 (7.8); 8.5846 (6.3); 8.3939 (4.4); 8.3907 (4.4); 8.2393 (3.5); 8.2177 (4.2); 7.9399 (2.4); 7.9362 (2.4); 7.9182 (2.1); 7.9144 (2.1); 7.8181 (0.6); 7.8113 (5.9); 7.8059 (2.1); 7.7945 (2.9); 7.7889 (11.6); 7.7824 (1.4); 7.7493 (1.5); 7.7428 (11.2); 7.7373 (2.8); 7.7259 (2.2); 7.7205 (5.9); 7.7137 (0.5); 3.9059 (1.7); 3.8875 (6.1); 3.8689 (6.2); 3.8505 (1.8); 3.3286 (230.8); 2.6798 (0.6); 2.6756 (1.2); 2.6711 (1.7); 2.6665 (1.2); 2.6623 (0.6); 2.5246 (5.7); 2.5198 (8.6); 2.5111 (105.3); 2.5067 (208.6); 2.5022 (268.6); 2.4976 (191.4); 2.4931 (90.9); 2.3380 (0.6); 2.3335 (1.2); 2.3290 (1.7); 2.3244 (1.2); 2.3199 (0.6); 2.0756 (12.5); 1.3006 (6.5); 1.2822 (15.0); 1.2637 (6.4); 0.0079 (0.6); −0.0003 (20.4); −0.0086 (0.6) I-49 [00056] I-49: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8083 (0.3); 8.6780 (5.9); 8.6557 (8.6); 8.6030 (0.4); 8.5600 (8.6); 8.5378 (6.5); 8.4121 (0.6); 8.3464 (14.6); 8.0962 (5.6); 8.0737 (6.1); 8.0602 (4.3); 8.0544 (4.3); 7.6167 (2.5); 7.6105 (2.4); 7.5944 (2.3); 7.5883 (2.3); 7.4460 (0.4); 3.8696 (1.8); 3.8511 (6.4); 3.8326 (6.5); 3.8143 (1.9); 3.3293 (326.8); 3.1006 (0.7); 3.0900 (1.2); 3.0841 (1.4); 3.0734 (2.8); 3.0645 (1.4); 3.0574 (1.2); 3.0461 (0.7); 2.6800 (0.9); 2.6756 (2.0); 2.6711 (2.7); 2.6666 (1.9); 2.6620 (0.9); 2.5246 (8.8); 2.5198 (13.3); 2.5111 (165.3); 2.5067 (329.9); 2.5021 (426.0); 2.4975 (302.2); 2.4930 (142.3); 2.3379 (0.9); 2.3335 (1.9); 2.3289 (2.7); 2.3244 (1.9); 2.3199 (0.9); 1.7638 (0.8); 1.2800 (6.9); 1.2616 (16.0); 1.2431 (6.8); 1.1731 (0.4); 1.1398 (0.6); 0.9883 (0.6); 0.9761 (3.2); 0.9690 (7.1); 0.9658 (7.8); 0.9624 (8.8); 0.9579 (5.9); 0.9500 (3.4); 0.9461 (4.5); 0.9403 (3.0); 0.9181 (0.4); 0.1459 (1.4); 0.0080 (11.1); −0.0002 (341.5); −0.0086 (11.3); −0.1495 (1.4) I-50 [00057] I-50: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.6893 (5.4); 8.6671 (7.9); 8.5901 (0.3); 8.5728 (8.1); 8.5506 (5.9); 8.4185 (0.5); 8.3750 (5.4); 8.3491 (14.0); 8.2227 (4.0); 8.2010 (4.7); 7.9285 (2.8); 7.9254 (2.8); 7.9065 (2.4); 7.9037 (2.4); 3.8760 (2.0); 3.8576 (6.9); 3.8391 (7.0); 3.8206 (2.1); 3.3278 (165.5); 3.1019 (0.8); 3.0914 (1.3); 3.0851 (1.5); 3.0747 (2.8); 3.0657 (1.6); 3.0587 (1.3); 3.0474 (0.8); 2.6755 (1.2); 2.6710 (1.7); 2.6667 (1.2); 2.5242 (5.9); 2.5105 (103.5); 2.5065 (202.3); 2.5021 (263.4); 2.4977 (195.0); 2.3333 (1.2); 2.3290 (1.6); 2.3246 (1.2); 2.0862 (2.7); 1.7960 (0.7); 1.2833 (7.2); 1.2649 (16.0); 1.2464 (7.2); 1.1399 (0.4); 0.9887 (0.7); 0.9694 (8.4); 0.9630 (10.3); 0.9504 (3.9); 0.9467 (5.1); 0.9411 (3.5); 0.9191 (0.4); −0.0003 (1.0) I-51 [00058] I-51: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8824 (16.0); 8.8636 (4.7); 8.8590 (4.6); 8.7643 (5.8); 8.7420 (8.2); 8.6311 (8.1); 8.6088 (6.6); 8.4572 (3.8); 8.4353 (6.1); 8.4138 (0.6); 8.3679 (3.1); 8.3631 (3.0); 8.3460 (2.0); 8.3412 (2.0); 7.8150 (0.7); 7.8074 (7.3); 7.8021 (2.5); 7.7906 (2.9); 7.7851 (10.7); 7.7777 (1.1); 7.7646 (0.5); 7.7424 (0.6); 7.6871 (1.2); 7.6796 (10.5); 7.6742 (2.8); 7.6627 (2.5); 7.6573 (7.5); 7.6498 (0.6); 7.5867 (0.6); 7.5643 (0.5); 5.7589 (3.1); 3.9046 (1.6); 3.8860 (5.9); 3.8675 (6.0); 3.8491 (1.7); 3.3309 (242.3); 2.6803 (0.4); 2.6760 (0.8); 2.6715 (1.1); 2.6669 (0.8); 2.6624 (0.4); 2.5250 (3.0); 2.5202 (4.7); 2.5116 (66.3); 2.5071 (135.4); 2.5025 (178.4); 2.4979 (127.1); 2.4933 (59.5); 2.3385 (0.4); 2.3339 (0.8); 2.3293 (1.1); 2.3247 (0.8); 2.3202 (0.4); 1.3064 (6.6); 1.2879 (15.5); 1.2694 (6.4); 1.2339 (0.3); 0.0080 (1.5); −0.0002 (49.9); −0.0085 (1.5) I-52 [00059] I-52: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8623 (4.8); 8.8577 (4.8); 8.8306 (16.0); 8.7623 (5.7); 8.7400 (8.1); 8.6344 (8.0); 8.6121 (6.3); 8.4558 (3.9); 8.4339 (6.3); 8.3674 (3.1); 8.3626 (3.0); 8.3532 (0.3); 8.3456 (2.0); 8.3407 (2.0); 7.8068 (0.4); 7.7979 (4.0); 7.7923 (1.5); 7.7858 (4.3); 7.7805 (2.5); 7.7751 (4.9); 7.7688 (1.5); 7.7631 (4.6); 7.7542 (0.4); 7.4769 (0.4); 7.4681 (4.8); 7.4624 (1.4); 7.4554 (0.6); 7.4509 (1.6); 7.4460 (7.6); 7.4411 (1.6); 7.4365 (0.5); 7.4296 (1.4); 7.4238 (4.3); 7.4149 (0.3); 5.7586 (3.1); 4.0382 (0.6); 4.0204 (0.6); 3.9032 (1.7); 3.8847 (6.1); 3.8663 (6.2); 3.8478 (1.8); 3.3618 (0.5); 3.3365 (243.0); 3.3218 (1.2); 2.6770 (0.5); 2.6724 (0.6); 2.6678 (0.5); 2.5258 (1.7); 2.5210 (2.7); 2.5124 (38.1); 2.5080 (77.9); 2.5034 (102.8); 2.4988 (73.4); 2.4943 (34.4); 2.3347 (0.4); 2.3302 (0.6); 2.3255 (0.4); 2.0124 (0.7); 1.9898 (2.7); 1.3066 (6.7); 1.2882 (15.3); 1.2696 (6.5); 1.2336 (0.5); 1.1927 (0.7); 1.1749 (1.4); 1.1571 (0.7); 0.8880 (0.7); 0.8712 (0.7); 0.0080 (0.8); −0.0002 (26.4); −0.0085 (0.7) I-53 [00060] I-53: .sup.1H-NMR (300.1 MHz, d.sub.6-DMSO): δ = 8.8704 (15.4); 8.7234 (5.3); 8.6939 (8.1); 8.5850 (8.1); 8.5554 (5.8); 8.2298 (6.4); 8.2238 (6.5); 7.9564 (5.0); 7.9273 (6.8); 7.8091 (7.2); 7.8022 (2.7); 7.7799 (14.6); 7.7749 (6.1); 7.7518 (3.3); 7.7453 (3.2); 7.7088 (0.4); 7.6874 (1.6); 7.6781 (11.4); 7.6710 (3.4); 7.6553 (2.7); 7.6484 (7.3); 7.6388 (0.8); 4.2221 (0.6); 4.0408 (0.6); 4.0171 (0.6); 3.8933 (1.8); 3.8686 (6.3); 3.8439 (6.5); 3.8194 (2.0); 3.3245 (46.4); 2.7295 (0.4); 2.5134 (18.9); 2.5077 (37.5); 2.5019 (49.7); 2.4960 (35.4); 2.0858 (0.4); 2.0754 (1.9); 1.9891 (2.5); 1.3357 (0.3); 1.2975 (7.8); 1.2729 (16.0); 1.2580 (3.0); 1.2482 (7.7); 1.2333 (4.8); 1.1980 (1.1); 1.1743 (1.5); 1.1505 (0.8); 0.9359 (0.5); 0.9115 (1.0); 0.8868 (0.5); 0.8737 (0.3); 0.8525 (0.8); 0.8295 (0.5); 0.0104 (0.3); −0.0004 (8.8); −0.0115 (0.4) I-54 [00061] I-54: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.9004 (16.0); 8.7396 (5.7); 8.7174 (8.6); 8.6272 (8.4); 8.6050 (6.4); 8.3911 (4.5); 8.3877 (4.5); 8.3161 (1.3); 8.2417 (3.6); 8.2200 (4.3); 7.9388 (2.4); 7.9351 (2.4); 7.9169 (2.1); 7.9131 (2.1); 7.7136 (1.7); 7.7110 (1.9); 7.7087 (2.0); 7.6962 (1.8); 7.6911 (3.5); 7.6887 (3.1); 7.6812 (3.7); 7.6767 (5.3); 7.6722 (2.4); 7.6199 (2.7); 7.6002 (5.0); 7.5803 (2.4); 7.4587 (2.4); 7.4562 (2.8); 7.4542 (2.6); 7.4517 (2.2); 7.4391 (1.9); 7.4366 (2.2); 7.4347 (2.1); 7.4321 (1.8); 3.9045 (1.8); 3.8862 (6.3); 3.8677 (6.4); 3.8493 (1.8); 3.3280 (455.6); 2.6803 (1.2); 2.6759 (2.5); 2.6714 (3.5); 2.6668 (2.5); 2.6622 (1.2); 2.5249 (11.3); 2.5201 (17.1); 2.5114 (203.0); 2.5070 (406.9); 2.5024 (530.2); 2.4978 (380.0); 2.4932 (181.2); 2.3383 (1.1); 2.3337 (2.4); 2.3292 (3.4); 2.3246 (2.4); 2.3203 (1.1); 2.0747 (0.8); 1.8537 (2.2); 1.8411 (6.9); 1.8339 (6.9); 1.8224 (2.8); 1.7830 (0.4); 1.6693 (0.3); 1.6311 (2.8); 1.6186 (6.6); 1.6115 (7.0); 1.5981 (2.1); 1.3035 (6.8); 1.2850 (16.0); 1.2665 (6.7); 1.2362 (0.5); 0.1460 (1.3); 0.0081 (10.8); −0.0001 (338.3); −0.0084 (10.8); −0.0178 (0.5); −0.1495 (1.4) I-55 [00062] I-55: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 9.0311 (11.3); 8.8624 (7.0); 8.7775 (4.8); 8.7554 (6.4); 8.6332 (6.8); 8.6111 (9.3); 8.5246 (0.3); 8.4558 (4.3); 8.4338 (6.9); 8.3836 (0.4); 8.3654 (4.8); 8.3435 (2.9); 8.3158 (1.1); 8.2493 (2.4); 8.2394 (2.7); 8.2262 (3.3); 8.2168 (3.2); 8.1029 (1.8); 8.0964 (1.8); 8.0818 (2.7); 8.0746 (2.7); 8.0607 (1.4); 8.0528 (1.3); 3.9189 (2.4); 3.9010 (7.0); 3.8823 (7.1); 3.8644 (2.4); 3.8224 (0.3); 3.8020 (0.4); 3.5921 (0.3); 3.5713 (0.3); 3.5057 (0.4); 3.4969 (0.4); 3.4870 (0.4); 3.3276 (453.4); 3.2368 (0.4); 2.7232 (0.6); 2.7111 (0.6); 2.6712 (5.7); 2.5024 (854.1); 2.3842 (0.5); 2.3666 (0.4); 2.3294 (5.3); 2.0856 (0.7); 1.4720 (0.3); 1.4652 (0.4); 1.4494 (0.3); 1.3800 (0.4); 1.3671 (0.4); 1.3128 (7.8); 1.2945 (16.0); 1.2760 (7.9); 1.2589 (1.9); 1.2347 (5.2); 1.2015 (0.8); 1.1971 (0.8); 1.1905 (0.7); 1.1791 (0.7); 1.1455 (0.7); 1.1308 (0.6); 1.1048 (0.5); 0.8999 (0.3); 0.8819 (0.5); 0.8533 (0.8); 0.8346 (0.5); 0.1456 (2.2); 0.0718 (0.9); −0.0001 (409.3); −0.1499 (2.2) I-56 [00063] I-56: .sup.1H-NMR (400.2 MHz, d.sub.6-DMSO): δ = 8.8252 (16.0); 8.7411 (5.8); 8.7189 (8.4); 8.6125 (8.1); 8.5903 (6.4); 8.3880 (4.6); 8.3849 (4.6); 8.3151 (0.6); 8.2369 (3.6); 8.2153 (4.3); 7.9368 (2.5); 7.9333 (2.5); 7.9150 (2.1); 7.9113 (2.2); 7.8065 (0.4); 7.7976 (4.2); 7.7920 (1.6); 7.7855 (4.5); 7.7802 (2.6); 7.7748 (5.1); 7.7684 (1.6); 7.7627 (4.8); 7.7540 (0.4); 7.4742 (0.4); 7.4654 (5.0); 7.4597 (1.5); 7.4528 (0.7); 7.4481 (1.8); 7.4434 (7.9); 7.4385 (1.8); 7.4268 (1.4); 7.4212 (4.4); 7.4122 (0.4); 3.9048 (1.8); 3.8863 (6.3); 3.8678 (6.4); 3.8493 (1.9); 3.3348 (391.6); 2.6811 (0.4); 2.6766 (1.0); 2.6721 (1.4); 2.6676 (1.0); 2.6631 (0.5); 2.5256 (4.4); 2.5209 (6.8); 2.5121 (83.0); 2.5077 (166.9); 2.5031 (218.4); 2.4986 (158.4); 2.4941 (76.9); 2.3390 (0.5); 2.3345 (1.0); 2.3299 (1.4); 2.3254 (1.0); 2.0867 (2.1); 1.3024 (6.9); 1.2840 (15.8); 1.2655 (6.8); 1.2340 (0.4); 0.1459 (0.5); 0.0080 (3.8); −0.0002 (116.4); −0.0085 (3.7); −0.1496 (0.5)

Use Examples

Diabrotica Balteata—Spray Test

[0551]

TABLE-US-00002 Solvent: 78 parts by weight of acetone 1.5 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0552] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water.

[0553] Pre-swollen wheat grains (Triticum aestivum) are incubated in a multiwell plate filled with agar and a little water for one day (5 seed grains per cavity). The germinated wheat grains are sprayed with an active compound formulation of the desired concentration. Subsequently, each cavity is infected with 10-20 beetle larvae of Diabrotica balteata.

[0554] After 7 days, the efficacy in % is determined. 100% means that all wheat plants have grown as in the untreated, uninfected control; 0% means that no wheat plant has grown.

[0555] In this test, for example, the following compounds from the preparation examples show an efficacy of 100% at an application rate of 500 g/ha (=160 μg/cavity): I-05, I-06, I-07, I-08, I-10, I-11, I-12, I-13, I-14, I-15, I-16, I-17.

[0556] In this test, for example, the following compounds from the preparation examples show an efficacy of 100% at an application rate of 125 g/ha (=40 μg/cavity): I-05, I-06, I-07.

[0557] In this test, for example, the following compounds of the Preparation Examples show an activity of 100% at an application rate of 100 g/ha: I-10, I-11, I-12, I-13, I-14, I-15, I-16, I-17, I-18, I-19, I-20, I-21, I-22, I-23, I-24, I-25, I-26, I-30, I-39, I-40, I-41, I-44, I-45, I-48, I-50, I-52, I-53, I-54, I-55, I-56.

[0558] In this test, for example, the following compounds of the Preparation Examples show an activity of 80% at an application rate of 100 g/ha: I-08, I-42, I-43, I-46, I-47, I-49.

[0559] In this test, for example, the following compounds from the preparation examples show an efficacy of 100% at an application rate of 31.25 g/ha (=10 μg/cavity): I-05, I-06, I-07.

[0560] In this test, for example, the following compounds of the Preparation Examples show an activity of 100% at an application rate of 20 g/ha: I-08, I-12, I-13, I-15, I-17, I-19, I-20, I-22, I-24, I-25, I-26, I-28, I-30, I-31, I-41, I-46, I-49, I-50, I-52, I-54, I-56.

[0561] In this test, for example, the following compounds of the Preparation Examples show an activity of 80% at an application rate of 20 g/ha: I-09, I-10, I-44, I-45, I-47.

Meloidogyne incognita Test

TABLE-US-00003 Solvent: 125.0 parts by weight of acetone

[0562] To produce an appropriate active ingredient formulation, 1 part by weight of active ingredient is mixed with the stated amount of solvent and the concentrate is diluted to the desired concentration with water.

[0563] Vessels are filled with sand, active ingredient solution, an egg/larvae suspension of the southern root-knot nematode (Meloidogyne incognita) and lettuce seeds. The lettuce seeds germinate and the plants develop. The galls develop on the roots.

[0564] After 14 days, the nematicidal efficacy in % is determined by the formation of galls. 100% means that no galls were found; 0% means that the number of galls on the treated plants corresponds to the untreated control.

[0565] In this test, for example, the following compounds from the preparation examples show an efficacy of 100% at an application rate of 20 ppm: I-18.

[0566] In this test, for example, the following compounds from the preparation examples show an efficacy of 90% at an application rate of 20 ppm: I-43.

Myzus persicae—Oral Test

TABLE-US-00004 Solvent: 100 parts by weight of acetone

[0567] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the specified parts by weight of solvent and made up with water until the desired concentration is attained.

[0568] 50 μl of the active compound formulation are transferred into microtitre plates and made up to a final volume of 200 μl with 150 μl of IPL41 insect medium (33%+15% sugar). Subsequently, the plates are sealed with parafilm, which a mixed population of green peach aphids (Myzus persicae) within a second microtitre plate is able to puncture and imbibe the solution through.

[0569] After 5 days, the efficacy in % is determined. 100% means that all the aphids have been killed; 0% means that no aphids have been killed.

[0570] In this test, for example, the following compounds from the preparation examples show an efficacy of 100% at an application rate of 4 ppm: I-01, I-03, I-04, I-05.

[0571] In this test, for example, the following compounds from the preparation examples show an efficacy of 90% at an application rate of 4 ppm: I-02, I-06, I-14, I-16.

Myzus persicae—Spray Test

TABLE-US-00005 Solvent: 78 parts by weight of acetone 1.5 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0572] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water.

[0573] Discs of Chinese cabbage leaves (Brassica pekinensis) infested by all stages of the green peach aphid (Myzus persicae) are sprayed with an active compound formulation of the desired concentration.

[0574] After 5 days, the efficacy in % is determined. 100% means that all the aphids have been killed; 0% means that no aphids have been killed.

[0575] In this test, for example, the following compounds of the Preparation Examples show an activity of 100% at an application rate of 100 g/ha: I-03.

Nezara viridula—Spray Test

TABLE-US-00006 Solvent: 78.0 parts by weight of acetone 1.5 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0576] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water.

[0577] Barley plants (Hordeum vulgare) are sprayed with an active compound formulation of the desired concentration and are infected with larvae of the Southern green shield bug (Nezara viridula).

[0578] After 4 days, the efficacy in % is determined. 100% means that all of the shield bugs have been killed; 0% means that none of the shield bugs have been killed.

[0579] In this test, for example, the following compounds of the Preparation Examples show an activity of 100% at an application rate of 500 g/ha: I-33, I-35, I-36, I-39, I-41, I-44, I-45, I-47, I-52, I-56.

[0580] In this test, for example, the following compounds of the Preparation Examples show an activity of 90% at an application rate of 500 g/ha: I-42, I-43, I-46.

Phaedon cochleariae—spray Test

TABLE-US-00007 Solvent: 78.0 parts by weight of acetone 1.5 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0581] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water.

[0582] Discs of Chinese cabbage leaves (Brassica pekinensis) are sprayed with an active compound formulation of the desired concentration and, after drying, populated with larvae of the mustard beetle (Phaedon cochleariae).

[0583] After 7 days, the efficacy in % is determined. 100% means that all the beetle larvae have been killed; 0% means that no beetle larvae have been killed.

[0584] In this test, for example, the following compounds of the Preparation Examples show an activity of 100% at an application rate of 100 g/ha: I-01, I-02, I-03, I-04.

Spodoptera fruaiperda—Spray Test

TABLE-US-00008 Solvent: 78.0 parts by weight of acetone 1.5 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0585] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water.

[0586] Leaf discs of maize (Zea mays) are sprayed with an active compound formulation of the desired concentration and, after drying, populated with caterpillars of the fall armyworm (Spodoptera frugiperda).

[0587] After 7 days, the efficacy in % is determined. 100% means that all the caterpillars have been killed; 0% means that no caterpillar has been killed.

[0588] In this test, for example, the following compounds of the Preparation Examples show an activity of 100% at an application rate of 100 g/ha: I-01, I-02, I-03, I-04, I-05, I-06, I-07, I-08, I-09, I-11, I-12, I-13, I-14, I-15, I-16, I-19, I-20, I-21, I-22, I-23, I-24, I-25, I-26, I-28, I-30, I-31, I-38, I-39, I-40, I-41, I-42, I-44, I-45, I-46, I-47, I-48, I-49, I-50, I-52, I-53, I-54, I-55, I-56.

[0589] In this test, for example, the following compounds of the Preparation Examples show an activity of 83% at an application rate of 100 g/ha: I-43.

Comparative Experiments

[0590] Heliothis armigera Spray Test (HELIAR)

TABLE-US-00009 Solvent: 14 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0591] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water. If the addition of ammonium salts or/and penetrants is required, these are each added in a concentration of 1000 ppm to the formulation solution.

[0592] Cotton plants (Gossypium hirsutum) are sprayed with an active compound formulation of the desired concentration and, after drying, populated with caterpillars of the cotton bollworm (Heliothis armigera).

[0593] After the desired time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.

[0594] In this test, for example, the following compounds from the preparation examples show superior efficacy to the prior art: see table.

Plutella xylostella Spray Test (PLUTMA)

TABLE-US-00010 Solvent: 14 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0595] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water. If the addition of ammonium salts or/and penetrants is required, these are each added in a concentration of 1000 ppm to the formulation solution.

[0596] Cabbage leaves (Brassica oleracea) are sprayed with an active compound formulation of the desired concentration and infected with larvae of the diamondback moth (Plutella xylostella).

[0597] After the desired time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.

[0598] In this test, for example, the following compounds from the preparation examples show superior efficacy to the prior art: see table.

Spodoptera frugiperda—Spray Test (SPODFR)

TABLE-US-00011 Solvent: 14 parts by weight of dimethylformamide Emulsifier: alkylaryl polyglycol ether

[0599] To produce a suitable active compound formulation, 1 part by weight of active compound is dissolved using the stated parts by weight of solvent and made up with water containing an emulsifier concentration of 1000 ppm until the desired concentration is attained. To produce further test concentrations, the formulation is diluted with emulsifier-containing water. If the addition of ammonium salts or/and penetrants is required, these are each added in a concentration of 1000 ppm to the formulation solution.

[0600] Cotton leaves (Gossypium hirsutum) are sprayed with an active compound formulation of the desired concentration and populated with caterpillars of the armyworm (Spodoptera frugiperda).

[0601] After the desired time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.

[0602] In this test, for example, the following compounds from the preparation examples show superior efficacy to the prior art: see table.

TABLE-US-00012 Substance Structure Object Concentration % efficacy dat Ex. I-34 Known from WO2017/055185 [00064] HELIVI PLUTMA SPODFR   4 ppm   4 ppm 0.8 ppm  0  0  0 7 dat 7 dat 7 dat Ex. I-04 According to the invention [00065] HELIVI PLUTMA SPODFR   4 ppm   4 ppm 0.8 ppm 100 100 100 7 dat 7 dat 7 dat Ex. I-016 Known from WO2018/141954 [00066] HELIVI PLUTMA SPODFR   4 ppm 0.8 ppm 0.8 ppm 0.8 ppm  55  10  70  65 7 dat 7 dat 7 dat 7 dat Ex. I-02 According to the invention [00067] HELIVI PLUTMA SPODFR   4 ppm 0.8 ppm 0.8 ppm 0.8 ppm 100 100 100 100 7 dat 7 dat 7 dat 7 dat dat = days after treatment