Topical composition
11547646 · 2023-01-10
Assignee
Inventors
Cpc classification
A61Q17/04
HUMAN NECESSITIES
International classification
Abstract
The present invention relates to topical compositions comprising D-panthenol, bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT) and hydroxyacetophenone (HAP) in specific weight ratios which show less staining.
Claims
1. A topical composition exhibiting reduced textile staining, the topical composition comprising: (i) bis-ethylhexyloxyphenol methoxyphenyl triazine, (ii) 3.0 to 20.0 wt. %, based on total weight of the composition, of D-panthenol, and (iii) p-hydroxyacetophenone, wherein a weight-ratio of the D-panthenol to the bis-ethylhexyloxyphenol methoxyphenyl triazine is at least 1.1, wherein a weight ratio of the p-hydroxyacetophenone to the bis-ethylhexyloxyphenol methoxyphenyl triazine is in a range of 0.05 to 1, and wherein the topical composition exhibits a reduction of yellow staining of a textile after washing by 35% or more as compared to a topical composition not having the weight ratio of the D-panthenol to the bis-ethylhexyloxyphenol methoxyphenyl triazine of at least 1.1.
2. The topical composition according to claim 1, wherein the ratio of the D-panthenol to the bis-ethylhexyloxyphenol methoxyphenyl triazine is at least 1.5.
3. The topical composition according to claim 1, wherein the weight ratio of the D-panthenol to the bis-ethylhexyloxyphenol methoxyphenyl triazine is at least 1.75.
4. The topical composition according to claim 1, wherein the D-panthenol is present in an amount of 3.0 to 5 wt. %.
5. The topical composition according to claim 1, wherein the bis-ethylhexyloxyphenol methoxyphenyl triazine is present in an amount from 0.4 to 10 wt. %, based on the total weight of the composition.
6. The topical composition according to claim 1, wherein the p-hydroxyacetophenone is present in an amount of 0.001 to 5 wt. %, based on the total weight of the composition.
7. The topical composition according to claim 1, wherein the composition is a cosmetic or pharmaceutical composition.
8. The topical composition according to claim 1, wherein the composition is a sun care product.
9. The topical composition according to claim 1, wherein the composition is an oil-in-water (O/W) emulsion comprising an oily phase dispersed in an aqueous phase in the presence of potassium cetyl phosphate as an O/W emulsifier.
Description
EXPERIMENTAL PART
(1) Cream formulations as outlined in table 1 have been prepared. Afterwards, cream has been applied on a cotton fabric with the following procedure: The textile (A5 size cut piece of a cotton textile) is fixed on top of a plastic bottle with an elastic strap. Bottle with fixed textile is placed on a balance. 0.36 g (+/−0.1 g) of sunscreen formulation is weighed on the fabric and homogenously distributed on an area with 5 cm diameter. Then the fabric has been dried for 15 minutes followed by measuring the L,a,b value of the spot.
(2) Afterwards, the fabric has been washed for 1 h in a beaker with 300 ml water and 1 g detergent at 40° C. under stirring, followed by rinsing the fabric in 300 ml fresh water for 15 minutes. After the fabric has been dried for 15 minutes the L,a,b value of the spot has been measured again. For each trial 3 separate fabrics have been used and accordingly each result is the average of 3 fabrics.
(3) Explanation of b value: the higher the b value, the more yellow is the fabric; the more negative the number is, the more white/bluish is the fabric.
(4) TABLE-US-00001 TABLE 1 Reference Reference Invention Invention 1 2 1 2 Ingredient Wt.-% Potassium Cetyl 1.5 1.5 1.5 1.5 Phosphate Stearyl Alcohol 3.0 3.0 3.0 3.0 Tridecyl Salicylate 11.0 11.0 11.0 11.0 C12-15 Alkyl Benzoate 11.0 11.0 11.0 11.0 Bis-Ethylhexyloxyphenol 2.5 2.5 2.5 2.5 Methoxyphenyl Triazine (BEMT) Hydroxyacetophenone 0.7 0.7 0.7 0.7 (HAP) Aqua q.s. q.s. q.s. q.s. Glycerin 3.0 3.0 3.0 3.0 Xanthan Gum 0.3 0.3 0.3 0.3 Phenoxyethanol, 0.5 0.5 0.5 0.5 Ethylhexylglycerin D-Panthenol / 1.0 3.0 5.0
(5) TABLE-US-00002 TABLE 2 Reference Reference Invention Invention 1 2 1 2 b value before washing 4.48 4.50 4.32 3.97 Reduction of yellow No −4% −11% staining after washing reduction vs. reference 1 b value after washing −1.05 −1.02 −1.42 −2.07 Reduction of yellow No −35% −97% staining after washing reduction vs. reference 1
(6) As can be retrieved from table 2, the addition of high amounts of D-panthenol to a topical composition comprising BEMT significantly reduced the staining thereof.