Further preparations of silk proteins, seed oils, monosaccharide, natural botanicals and polysaccharide mixtures in compositions for hair care or hair repair, and skin care and topical treatments

Abstract

The present invention intends to provide a composition for hair and skin treatment containing a combination consisting of silk amino acid and protein complexes, seed oils, polysaccharides, polyol, monosaccharide, and botanicals. The composition for hair and skin treatment containing the combination consisting of silk amino acid and protein complexes, seed oils, polysaccharides, and botanicals has excellent improvement effects on the condition of the hair follicle and cuticle, imparts moisture to dry hair; thereby reducing the damaging effects of psoriasis, eczema, alopecia, and seborrheic dermatitis. Furthermore, it imparts retention of moisture to the skin resulting in an improved appearance and diminished appearance of lines on the skin. This invention relates to the manufacture of personal care products to be applied to the hair and skin. The compositions may be in the form of hair conditioners, hair growth treatments, shampoos, skin care, skin cleansing, or anti-wrinkle products, and ointments.

Claims

1. A topical composition comprising: sericin; chitosan; and ribose; wherein the sericin, chitosan, and ribose are part of a first phase comprising water, and wherein the topical composition comprises a water-in-oil emulsion formed from the first phase and a second phase comprising at least one seed oil.

2. The topical composition of claim 1, further comprising Myrica rubra extract in the first phase.

3. The topical composition of claim 2, wherein the Myrica rubra extract is present in the first phase in a Myrica rubra extract concentration range of approximately 0.003% to 5%.

4. The topical composition of claim 1, wherein the ribose is present in the first phase in a ribose concentration range of approximately 0.001% to 3%.

5. The topical composition of claim 1, wherein the chitosan is present in the first phase in a chitosan concentration range of approximately 0.003% to 0.05%.

6. The topical composition of claim 1, further comprising quinoa extract.

7. The topical composition as in claim 1, further comprising kelp extract, sunflower seed extract, cucumber seed extract, grape seed extract, grapefruit seed extract, olive seed extract, or a combination of two or more thereof.

8. The topical composition of claim 1, further comprising flaxseed oil in a flaxseed oil concentration range of approximately 5 to 25%.

9. The topical composition of claim 1, further comprising silk amino acids in a silk amino acid concentration range of approximately 0.1% to 0.7%.

10. The topical composition of claim 1, wherein the sericin is present in a sericin concentration range of approximately 0.03% to 3%.

11. The topical composition of claim 1, wherein the emulsion comprises a nonionic, unsaturated, long-chain fatty acid ester of low hydrophilic/lipophilic balance value in combination with a high hydrophilic/lipophilic balance polyethoxylated fatty acid ester.

12. The composition of claim 1, further comprising olive oil, coconut oil, flaxseed oil, jojoba oil, sorbitan olivate, sucrose cocoate, behenyl alcohol, PCA glyceryl oleate, illipe butter, water, citrus pectin, sodium chloride, citric acid, hydrolyzed keratin, a silk amino acid, aloe vera, glycerin, potassium sorbate, Myrica rubra extract, sodium PCA, kelp extract, panthenol, sunflower seed extract, muira puama extract, vitamin E acetate, manuka oil, or a combination of two or more thereof.

13. The composition of claim 1, further comprising olive oil, sorbitan olivate, sucrose cocoate, PCA glyceryl oleate, hydroxypropyl methylcellulose, behenyl alcohol, cetyl alcohol, stearyl alcohol, vitamin A, vitamin B, vitamin C, glycosaminoglycan hyaluronic acid, green tea extract, Avena sativa kernel flour, kelp extract, Ho Shou Wu root extract, lanolin, or a combination of two or more thereof.

14. The composition of claim 1, wherein the topical composition is a cream, an oil, or a gel.

15. A method of treating a hair condition and/or a skin condition in a subject in need thereof, the method comprising administering to the subject an effective amount of the composition of claim 1 where the hair condition and/or skin condition is selected from the group consisting of a denatured protein structure of the hair, a degradation of at least one keratin protein of the hair, an obstruction of a hair cuticle on the skin, a decreased water content of the skin, dandruff, eczema, psoriasis, seborrheic dermatitis, or alopecia.

Description

EXPERIMENTAL DATA

(1) Water/Oil Preparation for Hair Care and Hair Growth Conditioner Phase A: Olive oil (5-25%), coconut oil (20-40%), Flaxseed oil (5-25%), jojoba oil (5-25%), Sorbitan olivate (1-9%), Sucrose cocoate (0.05-2%), Behenyl alcohol (1-5%), PCA Glyceryl Oleate (0.1-4%), Illipe butter (0.05-6%). Phase B: Purified water (5%-20%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.05%), Sodium chloride (0.003%-0.05%), Citric acid (0.1-1%), Hydrolyzed keratin (0.03%-3%), Silk amino acids (0.1%-0.7%), Sericin (0.03%-3%), Aloe vera (0.005%-1%), Glycerine (5-15%), Potassium sorbate (0.04-2%), D-ribose (0.001%-3%), Myrica rubra extract (0.003-5%), Sodium PCA (1%-13%), Kelp (0.01-2%), Panthenol (1-5%), Chitosan succinamide (0.1-5%), Sunflower seed extract (0.003-5%), Muira Puama extract (0.003-5%). Phase C: vitamin e acetate (0.04%-4%), Natural Fragrance (0.05%-3%), Manuka oil (0.05%-3%).

(2) Oil/Water Preparation for Leave-In Hair Care and Hair Growth Conditioner Phase A: Cucumber Seed extract (0.1-4%), Purified water (50-90%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.9%), citric acid (0.1-1%), Sericin (0.03%-3%), aloe vera (0.005%-1%), potassium sorbate (0.04-2%), D-ribose (0.001%-3%), Myrica rubra extract (0.003%-5%), Kelp (0.01-3%), Panthenol (1-5%), Sorbitol (1-11%), Chitosan succinamide (0.1-5%), Sunflower seed extract (0.003-5%), Muira Puama extract (0.003-5%). Phase B: Olive oil (5-10%), coconut oil (5-10%), Flaxseed oil (5-10%), jojoba oil (5-10%), Behentrimonium methosulfate (0.05-2%), Behenyl alcohol (0.5-5%), Illipe butter (0.05-6%). Phase C: vitamin e acetate (0.04%-4%), Natural Fragrance (0.05%-3%), Manuka oil (0.05%-3%).

(3) Oil/Water Preparation for Rinse Out Hair Care and Hair Growth Conditioner for Normal to Dry Hair Phase A: Honey (1-10%), Purified water (50-90%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.9%), citric acid (0.1-1%), hydrolyzed keratin (0.03%-5%), silk amino acids (0.1%-0.7%), Sericin (0.03%-3%), aloe vera (0.005%-1%), potassium sorbate (0.04-2%), D-ribose (0.001%-3%), Myrica rubra extract (0.003%-5%), Sunflower seed extract (0.01-3%), Chamomile flower extract (0.01-3%), Rosmarinus officinalis extract (0.01-3%), Arctium lappa extract (0.01-3%), Quinoa extract (0.01-3%), Panthenol (1-5%), Sorbitol (1-11%), Muira Puama extract (0.003-5%). Phase B: Sweet almond oil (1-10%), Avocado oil (1-10%), Sucrose cocoate (0.1-5%), Behentrimonium methosulfate (0.05-5%), Behenyl alcohol (0.05-5%). Phase C: vitamin e acetate (0.04%-4%), Natural Fragrance (0.05%-3%), Manuka oil (0.05%-3%).

(4) Oil/Water Preparation for Rinse Out Hair Care and Hair Growth Conditioner for Dry Hair Phase A: Honey (1-10%), Purified water (50-90%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.9%), citric acid (0.1-1%), hydrolyzed keratin (0.03%-5%), silk amino acids (0.1%-0.7%), Sericin (0.03%-3%), aloe vera (0.005%-1%), potassium sorbate (0.04-2%), D-ribose (0.001%-3%), Myrica rubra extract (0.003%-5%), Sunflower seed extract (0.01-3%), Chamomile flower extract (0.01-3%), Rosmarinus officinalis extract (0.01-3%), Arctium lappa extract (0.01-3%), Quinoa extract (0.01-3%), Panthenol (1-5%), Sorbitol (1-11%), Muira Puama extract (0.003-5%), Chitosan succinamide (0.1-5%). Phase B: Sweet almond oil (1-10%), Avocado oil (1-10%), Sucrose cocoate (0.1-5%), Behentrimonium methosulfate (0.05-5%), Behenyl alcohol (0.05-5%), Wipe butter (0.05-6%). Phase C: vitamin e acetate (0.04%-4%), Natural Fragrance (0.05%-3%), Manuka oil (0.05%-3%).

(5) Preparation for Hair Care and Hair Growth Shampoo Low Foam Phase A: Purified water (50-90%), Cocamidopropyl Hydroxysultaine (5-18%), Sodium Cocoyl Glutamate (3-10%), Yucca schidigera extract (1-10%), Saponaria officinalis (1-10%), Sucrose cocoate (1-10%), Soapwort root extract (1-10%). Phase B: Camellia oil (1-10%). Phased C: Honey (1-10%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.9%), citric acid (0.1-1%), Hydrolyzed keratin (0.03%-5%), silk amino acids (0.1%-0.7%), Sericin (0.03%-3%), potassium sorbate (0.04-2%), Glycerine (5-15%), D-ribose (0.001%-3%), Myrica rubra extract (0.003%-5%), Sodium PCA (0.01-5%), Hibiscus flower extract (0.01-3%), Ginger extract (0.01-3%), Green tea extract (0.01-3%), Sandalwood extract (0.01-3%), Rosehip extract (0.01-3%), Ginkbo biloba extract (0.01-3%), Mango extract (0.01-3%), Ashwaganda extract (0.01-3%), Kelp (0.01-3%), Allantoin (0.1-5%), Xanthan gum (0.1-3%), Sodium citrate (0.1-2%), Muira Puama extract (0.003-5%). Phase D: vitamin e acetate (0.04%-4%), Eucalyptus oil (0.01%-3%), Sage clary oil (0.01-3%), Natural Fragrance (0.05%-3%)

(6) Preparation for Hair Care and Hair Growth Shampoo no Foam Phase A: Purified water (50-90), Sucrose cocoate (1-15%). Phase B: Camellia oil (1-10%). Phased C: Honey (1-10%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.9%), citric acid (0.1-1%), Hydrolyzed keratin (0.03%-5%), silk amino acids (0.1%-0.7%), Sericin (0.03%-3%), potassium sorbate (0.04-2%), Glycerine (5-15%), D-ribose (0.001%-3%), Myrica rubra extract (0.003%-5%), Sodium PCA (0.01-5%), Hibiscus flower extract (0.01-3%), Ginger extract (0.01-3%), Green tea extract (0.01-3%), Sandalwood extract (0.01-3%), Rosehip extract (0.01-3%), Ginkbo biloba extract (0.01-3%), Mango extract (0.01-3%), Ashwaganda extract (0.01-3%), Kelp (0.01-3%), Allantoin (0.1-5%), Xanthan gum (0.1-3%), Sodium citrate (0.1-2%), Muira Puama extract (0.003-5%). Phase D: vitamin e acetate (0.04%-4%), Eucalyptus oil (0.01%-3%), Sage clary oil (0.01-3%), Natural Fragrance (0.05%-3%)

(7) Preparation for Carrier Oil-Free Smoothing Gel Phase A: Honey (1-10%), Purified water (50-90%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.9%), citric acid (0.1-1%), hydrolyzed keratin (0.03%-5%), silk amino acids (0.01%-0.7%), Sericin (0.03%-3%), potassium sorbate (0.04-2%), D-ribose (0.001%-3%), Myrica rubra extract (0.003%-5%), Sodium PCA (0.1-2%), Collagen amino acids (0.01-4%), Carob extract (0.01-3%), Grapeseed extract (0.01-3%), Grapefruit seed extract (0.01-3%), Rosmarinus officinalis extract (0.01-3%), Olive seed extract (0.01-3%), Seaweed codium vermilara extract (0.01-3%), Panthenol (1-5%), Sorbitol (1-11%), Polysorbate 60 (0.03-5%), Xanthan gum (0.02-2%). Phase B: vitamin e acetate (0.01%-4%), Fragrance (0.05%-3%)

(8) Preparation for Carrier Oil Containing Smoothing Gel Phase A: Honey (1-10%), Purified water (50-90%), Citrus pectin (0.001-0.05%), Chitosan (0.003-0.9%), citric acid (0.1-1%), hydrolyzed keratin (0.03%-5%), silk amino acids (0.01%-0.7%), Sericin (0.03%-3%), potassium sorbate (0.04-2%), D-ribose (0.001%-3%), Myrica rubra extract (0.003%-5%), Sodium PCA (0.1-2%), Collagen amino acids (0.01-4%), Carob extract (0.01-3%), Grapeseed extract (0.01-3%), Grapefruit seed extract (0.01-3%), Rosmarinus officinalis extract (0.01-3%), Olive seed extract (0.01-3%), Seaweed codium vermilara extract (0.01-3%), Panthenol (1-5%), Sorbitol (1-11%), Polysorbate 60 (0.03-5%), Xanthan gum (0.02-2%). Phase B: Plum kernel oil (1%-10%), Behentrimonium methosulfate (0.05-5%), Behenyl alcohol (0.05-5%), PCA Glyceryl Oleate (0.1-4%). Phase C: vitamin e acetate (0.01%-4%), Fragrance (0.05%-3%)

(9) General Procedure for Preparation of Hair Care and Hair Growth Conditioner and Gels Phase A was prepared in stainless-steel apparatus with agitation at low speed (approx. 200 rpm) and heated to 75 C-80 C. Phase B was prepared similarly with agitation at low speed and heating to 75 C-80 C. Phase A was then agitated at high speed (over 1000 rpm), subsequently Phase B was slowly added to Phase A. High speed agitation was continued for 5 minutes. The mixture was cooled to 45-50 C, then phase C was added to mixture and the mixture was allowed to cool to room temperature with low speed agitation.

(10) General Procedure for Preparation of Hair Care and Hair Growth Shampoo Phase A was prepared in stainless-steel apparatus with agitation at low speed (approx. 200 rpm) and heated to 75 C-80 C. Phase B followed by Phase C were added with agitation and heating to 75 C-80 C. The mixture was cooled to 45-50 C, then phase D was added to mixture and the mixture was allowed to cool to room temperature with low speed agitation.

(11) General Procedure for Preparation of Hair Care and Hair Growth Smoothing Gel Phase A was prepared in stainless-steel apparatus with agitation at low speed (approx. 200 rpm) and heated to 75 C-80 C. The mixture was cooled to 45-50 C, then phase B was added to mixture and the mixture was allowed to cool to room temperature with low speed agitation.

(12) Further Applications The emulsion systems for the W/O are currently composed of, but not limited to suitable monoester of fatty acids derived from olive oil and sorbitol (sorbitan olivate), and monoester of sucrose esters of coconut acids derivatives (sucrose cocoate). Suitable emulsion stabilizer is composed of, but not limited to individual components/or combination of single oleate derivative, PCA glyceryl oleate; propylene glycol ether derivatives of cellulose (hydroxypropyl methylcellulose); and/or long-chain fatty alcohols (behenyl alcohol, cetyl alcohol, stearyl alcohol, or other suitable long-chain fatty alcohols). The W/O emulsifier system may vary within limits. It is preferable to use a combination of nonionic, unsaturated, long-chain fatty acid ester of low hydrophilic/lipophilic balance (HLB) value in combination with a high HLB polyethoxylated fatty acid ester. These emulsions, which are in the form of creams, oils, gels, have good film-forming properties and give a very satisfactory sensation after they have been applied. Such emulsions can be used as skin care, skin cleansing. When these compositions are skin care products, including but not limited to anti-wrinkle products for improving the appearance of the skin. These can be used as skin care and anti-wrinkle products with the addition of a range of vitamins, including but not limited to vitamin A, B, C sources and derivatives derived thereof (0.05%-5%). Addition of carbohydrates is recommended, preferably, but not limited to the glycosaminoglycan hyaluronic acid (0.01%-2%). Addition of botanical extracts, preferably, but not limited to green tea extracts (0.5%-7%). Addition of exfoliating agents is recommended, preferably, but not limited to avena saliva kernel flour (0.05%-5%). These emulsions, which are in the form of creams, oils, and gels, based on their ability to promote hair growth, exhibit epidermal penetration properties, and give a very satisfactory sensation after they have been applied. Such emulsions can be used as topical ointments. These compositions may be suitable health care products, including, but not limited topical ointments for the relief of pain. These can be used as topical products with the addition of a range of vitamins, including but not limited to vitamin A, B, C sources and derivatives derived thereof (0.05%-5%). Addition of marine extracts is recommended, preferably, but not limited to kelp (0.05%-5%). Addition of botanical extracts, preferably, but not limited to Ho Shou Wu root extracts (0.005%-3%). Addition of high molecular weight wax is recommended, preferably, but not limited to medical grade lanolin (2%-20%).