SANITARY AID WITH ANTIBACTERIAL EFFECT FOR STABILIZATION OF PHYSIOLOGICAL BALANCE IN VAGINAL ENVIRONMENT AND/OR EXTERNAL GENITALIA

20190282725 ยท 2019-09-19

    Inventors

    Cpc classification

    International classification

    Abstract

    A sanitary aid with antibacterial effect for stabilization of physiological balance in vaginal environment and/or external genitalia is made by a backsheet impermeable layer, absorbent core formed by a mixture of absorbent and/or superabsorbent and a topsheet layer from woven or non-woven textile or from cellulose. The sanitary aid contains an effective component on the basis of at least one reactive form of oxygen, which is encapsulated by an encapsulation agent, where the effective substance is arranged on the topsheet layer of the sanitary aid designated for the contact with body and/or in the absorbent core. The sanitary aid is adapted for gradual release of reactive forms of oxygen, particularly hydrogen peroxide after contact with liquid from the sanitary aid, which causes the prolongation of the effect of reactive forms of oxygen with substantial disinfection ability.

    Claims

    1. A sanitary aid with antibacterial effect for stabilization of physiological balance in vaginal environment and/or external genitalia made by a backsheet impermeable layer, absorbent core formed by a mixture of absorbent and/or superabsorbent and a topsheet layer from woven or non-woven textile or from cellulose, containing an effective component on the basis of at least one reactive form of oxygen, which is arranged on the topsheet layer of a sanitary aid designated for the contact with body and/or in the absorbent core, characterized in that the reactive forms of oxygen are contained in the effective substance in the form encapsulated by an encapsulation agent, ensuring gradual release of reactive forms of oxygen after contact with liquid from the sanitary aid.

    2. The sanitary aid according to claim 1, characterized in that the reactive form of oxygen is in the form of complex of organic peroxide, particularly polyvinylpyrolidon-hydrogen peroxide or in the form of inorganic compounds of hydrogen peroxide, particularly magnesium peroxide, calcium peroxide, sodium percarbonate and sodium perborate or their mutual combinations.

    3. The sanitary aid according to claim 1, characterized in that the reactive form of oxygen is encapsulated by an encapsulation agent from the group: monolaurin, monoglycerides, stearanes, glyceryles, stearates, sterols, laurels, laureates and other derivatives of fatty acids, microcrystalline cellulose, hydroxypropylmethyl cellulose, omega-3 fatty acids, mannitol, sorbitol, xylitol, isomalt, humin compounds, sunflower oil, rapeseed oil, olive oil, carnauba wax, bee wax, phospholipids, lactic and whey proteins, casein, gelatin, gluten, paraffin, shellac or their mutual combinations.

    4. The sanitary aid according to claim 1, characterized in that the reactive form of oxygen is encapsulated in the ration 0.01 to 99 parts by weight of the reactive form of oxygen and 0.1 to 99.9 parts of the encapsulation agent, with advantage 1 up to 5 parts by weight of the reactive form of oxygen and 2 to 20 parts by weight of the encapsulation agent.

    5. The sanitary aid according to claim 1, characterized in that the effective substance is in the form of micronized particles with the size from 1 to 999 m, with an advantage from 1 to 100 m.

    6. The sanitary aid according to claim 1, characterized in that the topsheet layer contains a mixture formed by 0.01 to 99.99 parts by weight, with an advantage 50 to 90 parts by weight of the absorbent or superabsorbent and 0.01 to 50 parts by weight, with an advantage 5 to 20 parts by weight of an effective substance.

    7. The sanitary aid according to claim 1, characterized in that the absorbent core contains a mixture formed by 1 to 99.999 parts by weight, with an advantage 50 to 99.9 parts by weight of the absorbent or superabsorbent and 0.001 to 50 parts by weight, with an advantage 0.1 to 3 parts by weight of an effective substance.

    8. The sanitary aid according to claim 1, characterized in that it further contains freely arranged reactive forms of oxygen at the topsheet layer of the sanitary aid designated for contact with body and/or in the internal structure of the sanitary aid.

    9. The sanitary aid according to claim 1, characterized in that it further contains an auxiliary substance at the topsheet layer of the sanitary aid designated for contact with body and/or in the internal structure of the sanitary aid selected from the group: lactic acid, its pharmaceutically acceptable salt, lyophilized probiotic culture, prebiotic element, plant extracts, with an advantage herb extracts, titanium dioxide, antimicrobial metals, with an advantage silver, or their mutual mixtures.

    10. The sanitary aid based on claim 1, characterized in that it is made in the form of menstrual pads, towels or napkins, or daytime or overnight pads, or panty liners, or baby diapers, or incontinence pads or napkins, or tampons, or toilet paper, or paper tissues.

    Description

    DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS OF THE INVENTION

    Example 1

    [0025] The effective substance contains a reactive form of oxygen on the basis of 2-Pyrrolidinone,1-Ethenyl-, homopolymer, Hydrogen Peroxide or polyvinylpyrrolidone-hydrogen peroxide with the ability to release hydrogen peroxide, which is encapsulated by an encapsulation agent glyceryl monostrarate by a process of gentle grinding of a stirred mixture in a fragmentation grinder at the laboratory temperature without heating, in weight ratios (1:2, 1:1, 2:1). The encapsulate or the effective substance is homogenized with superabsorbent in the ratio of 1 part of effective substance and 99 parts of superabsorbent. Such prepared mixture is used for the production of an absorbent core of a menstrual pad. The mixture is applied in the absorbent core of a menstrual pad in the amount of 1.5 g.

    Example 2

    [0026] The effective substance contains a reactive form of oxygen on the basis of 2-Pyrrolidinone,1-Ethenyl-, homopolymer, Hydrogen Peroxide or polyvinylpyrrolidone-hydrogen peroxide with the ability to release hydrogen peroxide, which is encapsulated by an encapsulation agent glyceryl monostearate by a process of homogenization by grinding the mixture in a fragmentation grinder and the subsequent encapsulation or encapsulation in the presence of an organic solvent hexane. After encapsulation or encapsulation the distillation of the mixture was made until dry at the water bath temperature of 25 C. and the size of achieved parts is adjusted by sieving through a sieve with the size of 0.5 mm. The encapsulate or effective element is homogenized with superabsorbent in the ratio of 2 parts by weight of effective substance and 98 parts by weight of superabsorbent. Such prepared mixture is used for the production of an absorbent core of a menstrual pad. The mixture is applied in the absorbent core of a menstrual pad in the amount of 1.3 g.

    Example 3

    [0027] The effective substance contains a reactive form of oxygen on the basis of sodium perborate with the ability to release hydrogen peroxide, and is encapsulated by an encapsulation agent glyceryl monolaurate in the ratio of 1:3 in an industrial extruder with the regulation of temperature by a process of active cooling for the purpose of protection of reactive form of oxygen against breakdown by heat. Such prepared mixture is applied by a roller on the internal side of the topsheet from non-woven textiles in the amount of 1 g per 1 m.sup.2.

    Example 4

    [0028] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of polyvinylpyrolidone (PVP)-hydrogen peroxide encapsulated by an encapsulation agent magnesium stearate. The ratios for encapsulation are 2:1 (encapsulation agent:reactive form of oxygen), the encapsulation was carried out by a melting granulation in the ratio of 40 parts by weight of absorbent and 1 weight part of PPV-hydrogen peroxide. Such prepared mixture is used for the production of an absorbent core of a menstrual pad.

    Example 5

    [0029] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of (PVP)-hydrogen peroxide encapsulated by bee wax (ratios for encapsulation 2:1encapsulation agent:reactive form of oxygen) in the ratio of 100 parts by weight of absorbent and 1 weight part of the complex of PVP-hydrogen peroxide. Such prepared mixture was enriched by 1 weight part of sodium perborate and is used for the production of an absorbent core of a menstrual pad.

    Example 6

    [0030] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of polyvinylpyrolidone (PVP)-hydrogen peroxide encapsulated by magnesium stearate (ratios for encapsulation 2:1encapsulation agent: reactive form of oxygen) in the ratio of 40 parts by weight of absorbent and 1 part by weight of the encapsulated complex of PVP-hydrogen peroxide and 0.1 part by weight of non-encapsulated, that is non-encapsulated polyvinylpyrolidon (PVP)-hydrogen peroxide. Such prepared mixture is used for the production of an absorbent core of a menstrual pad in the amount of 1 g per pad.

    Example 7

    [0031] Superabsorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of polyvinylpyrolidon (PVP)-hydrogen peroxide encapsulated by a combination of glyceryl monostearate and gylceryl monolaurate (ratios for encapsulation 1:1:1encapsulation agent I:encapsulation agent II:reactive form of oxygen) in the ratio of 40 parts by weight of superabsorbent and 1 part by weight of encapsulated complex of PVP-hydrogen peroxide. Such prepared mixture is used for the production of an absorbent core of a menstrual pad.

    Example 8

    [0032] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex PVP-hydrogen peroxide in the ratio of 40 parts by weight of absorbent and 3 parts by weight of the complex of PVP-hydrogen peroxide and 0.2 parts by weight of encapsulated sodium perborate. Sodium perborate is encapsulated by carnauba wax in the weight ratio of 25% sodium perborate and 75% carnauba wax. The encapsulation takes place by intensive mixing of the wax warmed at 70 C. with sodium perborate. Such prepared mixture is used for the production of an absorbent core of a menstrual pad. The amount applied in the pad core is 2 g of the final mixture.

    Example 9

    [0033] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of PVP-hydrogen peroxide in the ratio of 40 parts by weight of absorbent and 3 parts by weight of the complex of PVP-hydrogen peroxide encapsulated by monoglyceride (encapsulation by melt granulation of the mixture of 70% by weight of monoglyceride and 30% by weight of PVP-hydrogen peroxide) and 1 part by weight of the sodium hydrogencarbonate. Such prepared mixture is used for the production of an absorbent core of a menstrual pad.

    Example 10

    [0034] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of sodium peroxide in the ratio of 40 parts by weight of absorbent and 3 parts by weight of sodium peroxide encapsulated by microcrystalline cellulose in the form of dry granulation of a mixture of 10% by weight of sodium peroxide and 90% of microcrystalline cellulose. Such prepared mixture is used for the production of an absorbent core of an incontinence napkin. The amount applied into the absorbent core of the napkin is 1 to 10 g of such prepared superabsorbent mixture.

    Example 11

    [0035] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of PVP-hydrogen peroxide in the ratio 40 parts by weight of absorbent and 3 parts by weight of the complex of magnesium peroxide encapsulated by shellac and 0.1 parts by weight of sodium hydrogencarbon for the adjustment of pH. Such prepared mixture is used for the production of an absorbent core of a sanitary incontinence napkin in the amount of 0.1 to 15 g or for applying on the inner side of the topsheet in the concentration of 0.5 per 1 m.sup.2.

    Example 12

    [0036] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of PVP-hydrogen peroxide in the ratio 80 parts by weight of the absorbent and 3 parts by weight of the complex of PVP-hydrogen peroxide encapsulated by melt granulation by monoglyceride and subsequently with the added 1 part by weight of monolaurin and 1 part by weight of crystalline lactic acid. Such prepared mixture is used for the production of an absorbent core of a baby diaper.

    Example 13

    [0037] At the topsheet layer of a feminine menstrual pad the amount of 0.1 g of powder is applied by a roller with a complex of PVP-hydrogen peroxide encapsulated by monoglyceride (encapsulation on fragmentation grinder 66.6% by weight of glyceryl monostearate and 33.4% by weight of PVP-hydrogen peroxide) in the mixture with mannitol in the ratio 1:9. The mixture is prepared in the ratio 10 parts by weight of mannitol and 1 part by weight of encapsulated complex of PVP-hydrogen peroxide. The absorbent core of a pad is enriched by aloe vera extract.

    Example 14

    [0038] At the topsheet layer of a feminine menstrual pad it is applied by a roller 0.1 g of powder with a complex of calcium peroxide encapsulated by monolaurin (encapsulation by melt granulation of the mixture in parts by weight of calcium peroxide:monolaurin in the ratio 1:10) in the mixture with mannitol in the ratio of 1 part by weight of reactive form of oxygen: 9 parts by weight of mannitol. The absorbent core of a pad is enriched by a probiotic element, i.e. inulin from chicory in the amount of 0.1 g per pad.

    Example 15

    [0039] At the topsheet layer of a feminine menstrual pad it is applied by a roller 0.1 g of powder with a complex of PVP-hydrogen peroxide encapsulated by stearane in the mixture with isomalt in the ratio 1:9. The mixture is prepared in the ratio of 10 parts by weight of isomalt and 1 part by weight of encapsulated complex of PVP-hydrogen peroxide. The absorbent core of a pad is enriched by 100 mg of cranberry extract.

    Example 16

    [0040] At the topsheet layer of a feminine menstrual pad it is applied by a roller 0.1 g of powder with a complex of PVP-hydrogen peroxide encapsulated by monoglyceride and monolaurin and stearane in the weight ratio 1:2:1 in the mixture with microcrystalline cellulose in the ratio 1:9. The mixture is prepared in the ratio of 10 parts by weight of microcrystalline cellulose a 1 part by weight of encapsulated complex of PVP-hydrogen peroxide. The absorbent core of a pad is enriched by 50 mg of tea tree extract.

    Example 17

    [0041] At the topsheet layer of a feminine menstrual pad it is applied by a roller 0.1 g of powder with a complex of sodium perborate encapsulated by a combination of monoglyceride, monolaurin and stearane in the mixture with mannitol in the ratio 1:9. The mixture is prepared in the ratio of 10 parts by weight of mannitol and 1 part by weight of complex of sodium perborate.

    Example 18

    [0042] At the topsheet layer of a sanitary incontinency pad or napkin it is applied by a roller 0.1 g of powder with a complex of sodium perborate encapsulated by monoglyceride in the mixture with sorbitol. The mixture is prepared in the ratio of 8 parts by weight of sorbitol and 1 part by weight of sodium perborate.

    Example 19

    [0043] At the topsheet layer of a feminine menstrual pad it is applied by a roller 0.1 g of powder with a complex of PVP-hydrogen peroxide encapsulated by shellac (encapsulation by PVP-hydrogen peroxide 1 part by weight:shellac 2 parts by weight, encapsulation by grinding at a fragmentation grinder) and a mixture of probiotic lyophilized culture Lactobacillus acidophilus or Bacillus coagulans in the amount of 1 billion CFU per pad.

    Example 20

    [0044] At the topsheet layer of a feminine menstrual pad it is applied by a roller 0.1 g of powder with a complex of PVP-hydrogen peroxide encapsulated by monoglyceride and monolaurin with an addition of probiotic lyophilized culture Lactobacillus acidophilus and a prebiotic element in the form of a plant soluble fiber-13 inulin or corn soluble fiber in the amount of 0.12 g per pad.

    Example 21

    [0045] At the topsheet layer of a feminine menstrual pad it is applied by a roller 0.12 g of powder with a complex of PVP-hydrogen peroxide encapsulated by a mixture of microcrystalline cellulose or MCC with sunflower oil (MCC 94% by weight:sunflower oil 6% by weight)encapsulation by dry granulation 1 part of PVP-hydrogen peroxide and 4 parts of a mixture of MCC with sunflower oil with an addition of extract from chamomile in the amount of 0.05 g per pad.

    Example 22

    [0046] At the topsheet layer of a feminine menstrual pad it is applied by a roller or a nozzle 0.05 g of powder with a complex of PVP-hydrogen peroxide encapsulated by monoglyceride in the mixture with non-encapsulated sodium perborate-calcium peroxide.

    Example 23

    [0047] At the inner layer of topsheet of an incontinence napkin it is applied by a roller or a nozzle 0.1 g of powder with the complex of PVP-hydrogen peroxide encapsulated in an extruder by monoglyceride and monolaurin (weight ratio 1:2:1) in the mixture with non-encapsulated PVP-hydrogen peroxide.

    [0048] Example 24

    [0049] At the topsheet layer of the feminine menstrual pad it is applied by a roller 0.08 g of powder with a complex of PVP-hydrogen peroxide encapsulated by monoglyceride in the mixture of monoglyceride encapsulated by sodium perborate.

    Example 25

    [0050] Absorbent forming the absorptive core of a baby diaper is, before applying into the napkin core, homogenized with a complex of PVP-hydrogen peroxide encapsulated by dry granulation by monoglyceride and monolaurin and stearane in the weight ratio 1:1:1:1. Such prepared mixture is used for the production of an absorbent core of a baby diaper.

    Example 26

    [0051] Absorbent forming the absorptive core of a sanitary incontinence aid is, before applying into the absorptive core, homogenized with a complex of PVP-hydrogen peroxide and sodium perboritane (1:1) encapsulated by monostearate 1:3. Such prepared mixture is used for the production of an absorbent core in a mixture with superabsorbent (5% mixture), whereas it is possible to add 1% by weight of sodium perboritane monohydrate, which may be micronized before application.

    Example 27

    [0052] Absorbent forming the absorptive core of a sanitary incontinence aid is, before applying into the absorptive core, homogenized with a complex of PVP-hydrogen peroxide encapsulated by stearane and carboxymethylcelullose in the ratio 15:1:3. Such prepared mixture may be further combined with sodium perborate.

    Example 28

    [0053] In the cellulose absorbent forming the absorptive core of a sanitary incontinency aid in a form of panty liner is apply a homogenate of the complex of PVP-hydrogen peroxide encapsulated by monoglyceride amonolaurin and hydroxymethylpropylcellulose in the ratio 3:8 is applied. Such prepared mixture is used for the production of the absorbent core of a panty liner.

    Example 29

    [0054] Absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with a complex of sodium peroxide encapsulated by a melt granulation by glyceryl monostearate in the ratio of 30 parts by weight of absorbent and 1 part by weight of the complex of PVP-hydrogen peroxide and 1 part by weight of microcrystalline cellulose and 0.00001 parts by weight silver. Such prepared mixture is used for the production of the absorbent core of a menstrual pad, in the optimum amount of 1 to 3 g per pad.

    Example 30

    [0055] At the surface layer of toilet paper it is applied by a roller 0.1 g power with the complex of PVP-hydrogen peroxide encapsulated by monoglyceride and monolaurin in the mixture with marigold extract.

    Example 31

    [0056] At the surface layer of toilet paper it is applied by a roller 0.02 g power with the complex of PVP-hydrogen peroxide encapsulated by monoglyceride in the mixture with sorbitol. The mixture is prepared in the ratio of 6 parts by weight of sorbitol and 1 part by weight of the encapsulated complex of PVP-hydrogen peroxide.

    Example 32

    [0057] Between layers of a paper tissue it is applied by a roller 0.01 g of powder with a complex of percarbonate encapsulated by melt granulation by monoglyceride and monolaurin in the ratio 1:3:2 in the mixture with tea tree and eucalypt extract. The mixture is prepared in the ratio of 2 parts by weight of encapsulated complex and 1 part by weight of plant extract and 2 parts by weight of microcrystalline cellulose. The mixture can be added also to unprocessed cellulose in the first step of the tissue production.

    Example 33

    [0058] The absorbent forming the absorptive core of a sanitary aid is, before applying into the absorptive core, homogenized with the complex of sodium perborate encapsulated by magnesium stearane (the weight ratios for encapsulation 3:1encapsulation agent:reactive form of oxygen) in the ratio of 60 parts by weight of absorbent and 1 part by weight of encapsulated sodium perborate. To such prepared mixture it may be added 0.1 parts by weight of crystalline lactic acid. The mixture is used for the production of the absorbent core of a menstrual pad. The amount of 1.2 g of the mixture is applied in the absorptive core.

    INDUSTRIAL APPLICABILITY

    [0059] The sanitary aid with antibacterial effect for stabilization of physiological balance in vaginal environment and/or external genitalia based on this invention can be used particularly in feminine hygiene in the form of menstrual pads, towels or napkins, daily and overnight pads, liners and tampons usable both at the time of menstruation as well as in the time between menstruations to ensure a quality feminine intimacy hygiene with the objective to stabilize physiological balance in vaginal environment and/or external genitalia. Furthermore, the sanitary aid can be used in routine baby hygiene in case of baby diapers as well as in incontinence aids, or toilet paper and paper tissues.