STABILISED MULTIPLE EMULSIONS AS SKIN PROTECTION PRODUCT

Abstract

The invention relates to stabilised multiple emulsions comprising the compounds a), b) and c), methods for the stabilisation of multiple emulsions and the use of multiple emulsions as skin protection products, in particular for protection against aqueous noxa, where: a) at least one aliphatic unbranched diol with 2 to 4 carbon atoms in the hydrocarbon chain, b) at least one further branched or unbranched aliphatic diol with 4 to 12 carbon atoms in the hydrocarbon chain that is different from a), whereby the hydrocarbon chain may be interrupted by an oxygen atom, c) at least one single-value aliphatic alcohol with 12 to 30 carbon atoms in the hydrocarbon chain.

Claims

1. Skin protection agent in the form of a stable water-in-oil-in-water multiple emulsion, comprising: a) 0.2 to 10% w/w of at least one diol selected from 1,2-propanediol, 1,3-propanediol, 1,2-ethanediol, 1,2-butanediol, 1,3-butanediol, and/or 1,4-propanediol; b) 0.1 to 1.5% w/w of at least one branched or unbranched aliphatic diol having 6 to 10 carbon atoms in the hydrocarbon chain, wherein the branched or unbranched aliphatic diol comprises at least one of ethylhexyl glycerine or 1,2-octanediol; c) 1.5 to 5% w/w of at least one alcohol selected from lauryl alcohol, cetyl alcohol, stearyl alcohol, ceryl alcohol and/or myricyl alcohol; d) optionally, 0.3 to 2% w/w of at least one further compound having one OH function and at least one unsaturated hydrocarbon ring with 6, 7 or 8 carbon atoms in the ring, wherein the further compound comprises at least one of phenoxyethanol and/or bisabolol; e) 1 to 25% w/w of an emulsifier mixture consisting of a combination of polyolpoly-12-hydroxy stearates with an alkyl and/or alkylene glucoside and a fatty alcohol and/or partial glyceride, and possible further co-emulsifiers including at least one ethoxylated dipolyhydroxy stearate; f) 50 to 85% w/w water; g) optionally, further components of a quantity to total 100%; wherein the skin protection agent is free from silicones, silicone containing compounds, and parabens, and wherein the water-in-oil-in-water multiple emulsion remains stable without phase separation or loss of the water-in-oil-in-water form over a period of six weeks at room temperature.

2. The skin protection agent of claim 1, wherein component a) is 1,2-propanediol.

3. The skin protection agent of claim 1, wherein component c) is cetyl alcohol, stearyl alcohol, or a mixture thereof.

4. The skin protection agent of claim 1, wherein component a) is present in an amount of 0.5 to 5% w/w.

5. The skin protection agent of claim 1, wherein component a) is present in an amount of 1 to 2.5% w/w.

6. The skin protection agent of claim 1, wherein component b) is present in an amount of 0.3 to 1.5% w/w.

7. The skin protection agent of claim 1, wherein component c) is present in an amount of 1.5 to 3% w/w.

8. The skin protection agent of claim 1, wherein component e) is present in amount of 2 to 15% w/w.

9. The skin protection agent of claim 1, wherein the skin protection agent is free of preservatives, whereby components a), b), and c) are not included under the term preservatives.

10. The skin protection agent of claim 1, wherein the water-in-oil-in-water multiple emulsion remains stable without phase separation or loss of the water-in-oil-in-water form over a period of six weeks at a temperature of 4 C.

11. The skin protection agent of claim 1, wherein the water-in-oil-in-water multiple emulsion remains stable without phase separation or loss of the water-in-oil-in-water form over a period of six weeks at a temperature of 40 C.

Description

EXAMPLES

[0120] Various W/O/W emulsions were produced and examined with regard to their multiplicity and their storage stability at different temperatures over a period of 6 weeks.

[0121] The multiplicity of drops was examined under the microscope and evaluated in line with the following scale:

TABLE-US-00001 Combination Conc. Multiplicity of components of the components Composition b) in % w/w M/O/W RT 40 C. 4 C. a), b), c) and 1,2-propandiol 1.00% ++ stable stable stable d) 1,2-hexandiol, caprylyl glycol, cetearyl alcohol bisabolol tropolone a), b), c) 1,2-propandiol 1.20% + stable stable stable caprylyl glycol, cetearyl alcohol glycerine a), b), c) 1,2-butandiol 1.20% + stable stable stable glyceryl caprylate, methyl propane diol cetearyl alcohol a), b), c) and 1,3-propandiol 1.00% ++ stable stable stable d) caprylyl glycol, hexylene glycol, cetearyl alcohol phenoxy ethanol a), b), c) 1,2-propandiol 1.00% ++ stable stable stable caprylyl glycol, ethyl hexyl glycerine cetearyl alcohol a), b), c) and 1,2-propandiol 2.00% + Cracks in 3 phases grainy, liquid d) caprylyl glycol, the product, on surface ethyl hexyl first oil glycerine, formation cetearyl alcohol alpha- tocopherol a), b), c) and 1,2-propandiol 1.00% +++ stable stable stable d) ethyl hexyl glycerine, cetearyl alcohol tocopherol phenoxy ethanol, a), b), c) and 1,2-propandiol 1.00% + stable stable stable d) caprylyl glycol, 1,2-hexanediol, cetearyl alcohol methylbenzyl alcohol a), b), c) and 1,2-propandiol 1.00% + stable stable stable d) ethyl hexyl glycerine, cetearyl alcohol alpha- tocopherol a), b), c) and ethyl hexyl 1.10% + stable stable stable d) glycerine lauryl alcohol, phenethyl alcohol, alpha- tocopherol a), b), c) and 1,2-ethandiol 1.50% +++ stable Slight Slight d) Caprylyl glycol, separation at separation at cetearyl alcohol bottom top phenoxy ethanol, glycerine c) cetearyl alcohol stable stable stable (Comparison trial) a) and b) 1,2-propandiol, 1.00% stable Separates, stable (comparison caprylyl glycol liquid at trial) bottom b), c) and d) methyl 1.50% stable Liquid Liquid (comparison propandiol, separation separation trial) glyceryl, on the on the caprylate surface surface cetearyl alcohol phenethyl alcohol a) and c) 1,2-propandiol, stable stable stable (comparison cetearyl alcohol trial) almost none or none of the drops show multiplicity + the majority of the drops show multiplicity ++ almost all of the drops show multiplicity +++ all of the drops show multiplicity

[0122] The comparison trials dearly show that only those skin protection agents according to the invention that comprise the components a), b) and c) will result in multiple W/O/W emulsions that are also stable. The absence of at least one of the components will result either in emulsions that are not multiple, and thus immediately disintegrate into a W/O or O/W emulsion and/or into skin protection agents that are less stable during storage.