MEDICAMENT DELIVERY DEVICE

Abstract

A medicament delivery device is presented having a tubular housing comprising a distal end and a proximal end; a medicament container arranged with a medicament delivery member and placed in the housing, a cap removably arranged on the proximal end of the housing and configured to cover the delivery member; a drive mechanism configured to act on the medicament container to expel the medicament through the medicament delivery member upon the drive mechanism is triggered; an activation member arranged coaxially movable in relation to the housing, associated with the drive mechanism and comprising a proximal tubular portion which extends from the proximal end of the housing and wherein for triggering the drive mechanism the activation member is axially moved towards the distal end of the housing after removing the cap from the housing. The proximal tubular portion of the activation member has a resilient element arranged with friction.

Claims

1-12. (canceled)

13: A medicament delivery device comprising: a tubular housing comprising a distal end and a proximal end; a medicament container arranged with a medicament delivery member and placed in the housing, a cap removably arranged on the proximal end of the housing and configured to cover the delivery member; a drive mechanism configured to act on the medicament container to expel the medicament through the medicament delivery member upon the drive mechanism is triggered; an activation member arranged coaxially movable in relation to the housing, associated with the drive mechanism and comprising a proximal tubular portion which extends from the proximal end of the housing and wherein for triggering the drive mechanism the activation member is axially moved towards the distal end of the housing after removing the cap from the housing; wherein the proximal tubular portion of the activation member comprises a resilient element arranged with a friction member; and the cap comprises an interaction member configured to radial force the resilient element and thereby causes the friction member to laterally engage with the housing when the cap is arranged on the proximal end of the housing; whereby an accidental axial movement of the activation member is prevented.

14: The medicament delivery device according to claim 13, wherein the friction member is laterally arranged on resilient element and is configured to interact with the inner surface of the proximal portion of the housing.

15: The medicament delivery device according to claim 13, wherein the proximal tubular portion comprises a lateral cut-out; wherein the cut-out defines the resilient element with a fixed end and a free end which is radially movable in relation to the proximal tubular portion; and wherein the friction member is arranged on the outer surface of the free end of the resilient element.

16: The medicament delivery device according to claim 13, wherein the proximal tubular portion comprises a lateral arranged pair of slots; wherein the pair of slots defines the resilient element; and wherein the friction member is arranged on the outer surface of the resilient element.

17: The medicament delivery device according to claim 13, wherein the friction member is radial outwardly protruding from resilient element and the proximal tubular portion.

18: The medicament delivery device according to claim 13, wherein the outer surface of the proximal tubular portion where the resilient element and the friction member is located, is at least partially surrounded by the inner surface of the proximal portion of the housing.

19: The medicament delivery device according to claim 13, wherein the interaction member of the cap is coaxially arranged within the proximal tubular portion.

20: The medicament delivery device according to claim 13, wherein the activation member is configured to trigger the drive mechanism when the activation member axially moves towards the distal end of the housing.

21: The medicament delivery device according to claim 13, wherein the medicament delivery device is further comprises a trigger button arranged on the housing and movable between a initial position to a trigger position; wherein the drive mechanism is triggered only when the trigger button is in its trigger position and the activation member is axially moved towards the distal end of the housing.

22: The medicament delivery device according to claim 21, wherein the trigger button is prevented from moving into its trigger position until the activation member is axially moved towards the distal end of the housing.

23: The medicament delivery device according to claim 13, wherein the proximal tubular portion is configured to completely surround the medicament delivery member when the activation member extends from the proximal end of the housing and the cap is removed from the proximal end of the housing.

24: The medicament delivery member according to claim 13, wherein the interaction member is coaxially arranged with the medicament delivery member when the cap is arranged on the proximal end of the housing.

25: A medicament delivery device comprising: a housing comprising a distal end and a proximal end; a medicament container having an attached medicament delivery member is positioned within the housing; a cap is removably attached to the proximal end of the housing, where the cap has an attached interaction member surrounding the delivery member; a drive mechanism that is biased such that when the medicament delivery device is triggered, a plunger rod moves proximally relative to the medicament container to expel medicament through the medicament delivery member; and an activation member slidably arranged within the housing and operatively engaged with the drive mechanism such that distal axial movement will trigger the drive mechanism, where the activation member comprises a proximal tubular portion having a resilient element arranged with a friction member, wherein the interaction member engages with and exerts an outward radial force on the resilient element that causes the friction member to laterally engage with the housing, and wherein the engagement of the interaction member with the resilient member will prevent an unintended axial movement of the activation member and the triggering of the medicament delivery device.

26: The medicament delivery member according to claim 25, wherein the interaction member is coaxially arranged within the proximal tubular portion.

27: The medicament delivery member according to claim 25, wherein the friction member interacts with an inner surface of the proximal end of the housing.

28: The medicament delivery member according to claim 25, wherein the resilient is formed from and defined by a lateral cut-out such that the resilient member has a fixed end and a free end which is radially movable relative to an outer surface of proximal tubular portion, where the friction member is arranged on the outer surface of the free end of the resilient element.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0038] The specific embodiments of the inventive concept will now be described, by way of example, with reference to the accompanying drawings, in which:

[0039] FIG. 1 displays a medicament delivery device.

[0040] FIG. 2A-2B display an activation member with a proximal tubular portion which is axially movable in relation to the housing of the medicament delivery device of FIG. 1.

[0041] FIG. 3A-3B display the proximal tubular portion of the activation member of the medicament delivery device of FIG. 1.

[0042] FIG. 4 displays a cap of the medicament delivery device of FIG. 1.

[0043] FIG. 5-6 display cross-section views of a mechanical arrangement of the accidental activation prevention of the medicament delivery device of FIG. 1.

[0044] FIG. 7 displays a cross-section view of the proximal tubular portion of the activation member when the cap is moved from the of the medicament delivery device of FIG. 1.

[0045] FIG. 8A-8B display cross-section views of the medicament delivery device of FIG. 1 arranged with and without the cap.

DETAILED DESCRIPTION

[0046] The inventive concept will now be described more fully hereinafter with reference to the accompanying drawings, in which exemplifying embodiments are shown. The inventive concept may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided by way of example so that this disclosure will be thorough and complete, and will fully convey the scope of the inventive concept to those skilled in the art. Like numbers refer to like elements throughout the description.

[0047] FIG. 1 illustrates a medicament delivery device with a tubular housing 1 which extends longitudinally along an axis L from a proximal end to a distal end; and a cap 2 arranged on the proximal end of the tubular housing 1. The tubular housing 1 is configured to accommodate a medicament container 5 containing a medicament and having a medicament delivery member 51 which is arranged on the proximal end of the medicament container 5 and arranged to deliver the medicament to an end user of the medicament delivery device.

[0048] The medicament delivery device also comprises a drive mechanism configured to act on the medicament container 5 to expel the medicament through the medicament delivery member 51 upon the drive mechanism is triggered. The drive mechanism comprises an energy source, such as a spring, a gas canister or a motor; a plunger rod which is biased by the energy source in the proximal direction and is configured to act on the medicament container 5 to expel the medicament through the medicament delivery member 51. The plunger rod may be hold against the energy source by a holding member before the drive mechanism is triggered; or the energy source may be prevented to output a force before the drive mechanism is triggered, such that the medicament can only be delivered upon the drive mechanism is triggered.

[0049] The medicament delivery device further comprises an activation member 3 arranged coaxially movable in relation to the housing 1 and associated with the drive mechanism. The activation member 3 comprises a proximal tubular portion 30 that extends from the proximal end of the housing 1 as shown in FIG. 2A. For triggering the drive mechanism, the activation member 3 is axially moved towards the distal end of the housing 1 by distally moving the proximal tubular portion 30, such as pressing the proximal end of the proximal tubular portion 30 onto the medicament delivery site, at least partially into the housing 1 as shown in FIG. 2B. The distal portion of the activation member 3 (not show) is configured to interact with the drive mechanism upon the distal movement of the activation member 3. Such as the distal portion of the activation member may move the holding member out from the engagement with the plunger rod; or release the holding member from the engagement with the plunger rod; or release the power source to output the force toward the plunger rod. The drive mechanism is thereby triggered.

[0050] The activation member 3 may be further associated with a trigger button (not show). The trigger button may be arranged on the distal end of the housing or on the lateral outer surface of the housing 1. The trigger button is movable between an initial position to an axially proximal trigger position or a transverse trigger position. The drive mechanism is arranged to be triggered only when the trigger button is in its axial proximal trigger position or traverse trigger position and the activation member is axially moved towards the distal end of the housing 1. The trigger button may be prevented from moving into its axial proximal trigger position or traverse trigger position until the activation member 3 is axially moved towards the distal end of the housing 1.

[0051] Since this aspect does not form part of the present disclosure, and since many different variations of such drive mechanism associated with the distal movement of the activation member and/or the movement of the trigger button can be realised, such as those drive mechanism disclosed in the cited prior art documents, this feature will not be discussed in any further detail herein.

[0052] FIG. 3A-3B illustrate the proximal tubular portion 30 of the activation member 3 of the medicament delivery device. The proximal tubular portion 30 comprises a resilient element 31, which is formed by a cut-out on the proximal tubular portion 30. A friction member 32 protrudes radially outwards from the lateral outer surface of the resilient element 31. The friction member 32 is configured to laterally interact with the inner surface 11 of the housing 1, such that the proximal tubular portion 30 is friction-fitted with housing 1 through the friction member 32. The friction member 32 may comprise a rough surface or a rubber surface to engage with the inner surface 11 of the housing 1 for increasing the friction between the friction member 32 and the housing 1. The friction member 32 may also comprise a chamfer surface for distributing the normal force evenly around interface between the friction member 32 and the inner surface 11 of the housing 1. The resilient element 31 comprises a fixed end 31a which is fixed to the proximal tubular portion 30; and a free end 31b which is radially movable in relation to the proximal tubular portion 30. The friction member 32 is arranged close to the free end 31a as shown in FIG. 3B. The inner surface of the free end 31b is arranged with an interaction protrusion 4 configured to interact with the cap 2.

[0053] FIG. 4 illustrates a cap 2 comprising an outer cap body 21 which is accessible by the end user; and an interaction member 22 arranged within the outer cap body 21. The interaction member 22 is configured to contact with the interaction protrusion 4 when the cap 2 is attached to the housing 1, the resilient element 31 is thereby forced radially outwards by the interaction member 22 such that the friction member 32 tightly engages with the inner surface 11 of the housing.

[0054] The interaction member 22 is configured to provide a pressing force or normal force on the resilient portion, so that the friction for retaining the proximal tubular portion 30 can be generated when the cap 2 is attached to the housing 1.

[0055] It should be noted that alternatively, the interaction protrusion can be re-arranged onto the interaction member of the cap, and configured to contact the flat inner surface of the resilient element of the proximal tubular portion. It is also feasible that the interaction protrusion can be removed, since the interaction member can be arranged with a slightly greater diameter than the inner diameter of the proximal tubular portion, such that the interaction member is compressed and assembled into the proximal tubular portion, and therefore the interaction member will provide the pressing force to the resilient element. To increase the friction generated by the friction member 32 and the inner surface 11 of the housing 1, it is preferred that the interaction member 22 creates less deformation on the resilient element 31; such that the pressing force from the interaction member 22 can be mainly transited into the pressing force or the normal force on the resilient element 31.

[0056] FIGS. 5-6 and FIG. 8A illustrates the mechanical arrangement of the accidental activation prevention of the present disclosure. When the cap 2 is attached to the housing 1, the interaction member 22 provides a constant bending force to the resilient element 31 through the contact with the interaction protrusion 4. The bending force provides the pressing force or the normal force to the friction member 32, such that the friction member 32 is friction-fitted to the inner surface 11 of the housing 1. An accidental axial movement of the activation member 3 is thereby prevented. When the cap 2 is detached from the housing 1, as shown in FIG. 7 and FIG. 8B, since there is no any support on the inner surface of the resilient element 31, the pressing force to the friction member 32 is also dismissed. The friction between the friction member 32 and the inner surface 11 of the housing 1 is therefore significantly reduced and is no longer able to fix the proximal tubular portion 30 and the activation member 3 to the housing 1. Such that the end user is able to trigger the drive mechanism by distally moving the activation member 3 to start the medicament delivery operation sequence.

[0057] It should be noted that alternatively, instead of the cut-out, the resilient element 31 can be defined by a lateral arranged pair of slots on the proximal tubular portion 30. Such as the free end 31b as described above can be re-arranged as a second fixed end, and the friction member 32 can be arranged between the two fixed ends.

[0058] The friction member 32 can also be alternatively arranged on the inner surface of the resilient element 31. Such arrangement is suitable for a housing with two layers proximal portion. In this embodiment, the proximal tubular portion is arranged between the outer layer housing and the inner layer housing; the interaction member of the cap is configured to contact the interaction protrusion or directly to the outer surface of the resilient element, such that the friction member is engaged with the outer surface of the inner layer of the housing and friction-fitted with housing.

[0059] The friction member 32, instead of protruding from either the inner or the outer surface of the resilient element 31, can be alternatively flat arranged on the inner or the outer surface of the resilient element 31. Similarly, the interaction protrusion 4 can also be removed, such that the interaction member 22 can directly contact on the inner or outer surface of the resilient element 31.

[0060] The proximal tubular portion 30 also acts as the delivery member cover, such that the proximal tubular portion 30 is configured to completely surround the medicament delivery member 51 when the activation member 3 extends from the proximal end of the housing 1 and the cap 2 is removed from the proximal end of the housing 1, as shown in FIG. 7 and FIG. 8B.

[0061] The interaction member 22 of the cap 2 can also serve as or be used with a delivery member sheath remover. Such that the interaction member 22 is coaxially arranged with the medicament delivery member 51 when the cap 2 is arranged on the proximal end of the housing 1, as shown in FIGS. 5-6 and FIG. 8A. The inner surface of the interaction member may be arranged with a gripper configured to grip on the medicament delivery member sheath; or a delivery member sheath remover comprising the grapper may be arranged within the interaction member. Therefore, the delivery member sheath can be removed with the removal of the cap 2 from the housing 1. If the cap 2 serves as or be used with a delivery member sheath remover, the friction between the delivery member and the delivery member sheath may cause the cap 2 can only be removed while a significant pulling force is applied to the cap 2. Therefore, the interface between the interaction member 22 and the interaction protrusion 4 can be smooth and provided with less friction. On the other hand, if the cap 2 is free from the function of delivery member sheath remover; or to more strongly keep the proximal tubular portion 3 immovable when the cap 2 is attached to the housing 1, the interface between the interaction member 22 and the interaction protrusion 4 can be also arranged with high friction, such as rough interface or rubber interface; therefore the proximal tubular portion 3 and so as the activation member can be friction-fitted with both the housing 1 and the cap 2.

[0062] The inventive concept has been described above with reference to a few examples. However, as is readily appreciated by a person skilled in the art, other embodiments than the ones disclosed above are equally possible within the scope of the inventive concept, as defined by the appended claims.