SKIN-CARE BALM AND DEVICE FOR INTERNAL AND EXTERNAL NASAL APPLICATION

Abstract

There is provided a skin-care balm comprising 15% to 45% (w/w) of two or more waxes, wherein a first wax has a melting point of 70° C. to 90° C. and a second wax has a melting point of 30° C. to 60° C., the balm further comprising 45% to 70% (w/w) of an emollient and a skin soothing agent. The skin-care balm can be applied to the skin in the perinasal area. There is also provided a combination product comprising a skin-care balm and a nasal spray product.

Claims

1. A skin-care balm comprising 15% to 45% (w/w) of two or more waxes, wherein a first wax has a melting point of 70° C. to 90° C. and a second wax has a melting point of 30° C. to 60° C., the balm further comprising 45% to 70% (w/w) of an emollient and a skin soothing agent.

2. A skin-care balm according to claim 1, wherein the first wax comprises rice bran wax, candelilla wax, bees wax, or any combination thereof.

3. A skin care balm according to claim 1, wherein the first wax is rice bran wax.

4. A skin-care balm according to claim 1, wherein the second wax comprises Rhus verniciflua peel cera, Rhus succedanea fruit cera, Shorea robusta resin, Euphorbia cerifera wax, or a mixture of two or more thereof.

5. A skin-care balm according to claim 1, wherein the emollient comprises octyldodecanol, caprylic/capric triglyceride, castor oil, avocado oil, cocoa butter, myristyl myristate, hydrogenated castor oil, shea butter, behenyl alcohol, cetyl esters, or any combination thereof.

6. A skin-care balm according to claim 1, wherein the emollient comprises 6% to 20% (w/w) of botanical butter.

7. A skin-care balm according to claim 1, wherein the emollient comprises a vegetable oil comprising unsaturated fatty acids.

8. A skin-care balm according to claim 6, wherein the emollient comprises 6% to 8% (w/w) of botanical butter which is cocoa.

9. A composition according to claim 1, wherein the emollient comprises a powdered hydrogenated castor oil.

10. A skin-care balm according to claim 1, wherein the skin soothing agent is Zanthoxylum bungeanum fruit extract.

11. A skin-care balm according to claim 1, further comprising eucalyptol, a eucalyptus essential oil, menthol, menthyl ethylamido oxalate, or any combinations thereof.

12. A skin-care balm according to claim 1, wherein the balm has a melting point in the range from 60° C. to 75° C.

13. A skin-care balm according to claim 12, wherein the balm has a melting point in the range from 65° C. to 72° C.

14. A skin-care balm according to claim 1, wherein the balm has a penetration value of 20 mm-40 mm.

15. A skin-care balm according to claim 14, wherein the balm has a penetration value of 25 mm to 35 mm.

16. A skin care balm according to claim 1, wherein the balm has a dome shape suitable to be applied directly to a perinasal area.

17. A method for the treatment of discomfort, dry skin, feeling of tension, scaliness, flaking, redness, soreness and/or irritation of skin in a perinasal area including the step of applying the skin care balm according to claim 1.

18. A method of treating a patient suffering from sore skin in the perinasal area comprising applying an effective amount of a skin-care balm according to claim 1 to skin in a perinasal area of a patient.

19. A method for reducing skin redness in a perinasal area, the method comprising applying a skin-care balm according to claim 1 to the reddened skin.

20. A method of emolliating, hydrating and/or calming skin in a perinasal area including the step of applying the skin care balm according to claim 1.

21. A method of using the skin care balm according to claim 1 in a combination product comprising a nasal spray and the skin care balm including the step of applying the skin care balm from the combination product.

22. A combination product comprising a nasal spray product and a skin-care balm according to claim 1.

23. A skin-care balm according to claim 7, wherein the emollient comprises 4% to 10% (w/w) of a vegetable oil which is avocado oil.

Description

DETAILED DESCRIPTION

Definitions

[0059] The terms wax and waxes, as used herein, comprise waxes and pseudo-waxes. Numerous waxes or pseudo-waxes of animal, plant or petroleum origin known in the art are suitable for the formulation of the balm. Pseudo-waxes are excipients that have physical properties similar to those of waxes but are not waxes in the chemical sense, i.e. esters of fatty acids with fatty alcohols. They may be mixtures of hydrocarbons and/or fatty acids and/or fatty alcohols and/or fatty acid esters and/or hydrogenated or unhydrogenated oils (triglycerides). Examples for hydrocarbons are petrolatum and paraffin.

[0060] Skin conditioning agent may be any agent that has positive impact on skin and can be a pharmaceutical or cosmetic ingredient. Emollients are a group of skin conditioning agents that can act as lubricants on the skin or that maintain, restore, enhance and or balance skin hydration or moisture.

[0061] Unless indicated otherwise, the percentages given are weight percentages (w/w). INCI means the International Nomenclature of Cosmetic Ingredients. This is a system of names for waxes, oils, pigments, chemicals and other ingredients of cosmetic products and the likes. INCI ingredient names are predominantly based upon the terminology created by the INC committee.

[0062] Elements, apparatus, and methods described herein, however, are not limited to the specific embodiments presented in the detailed description, examples, and figures. It should be recognized that the exemplary embodiments herein are merely illustrative of the principles of the present invention. Numerous modifications and adaptations will be readily apparent to those of skill in the art without departing from the spirit and scope of the invention.

[0063] In addition, all ranges disclosed herein are to be understood to encompass any and all subranges subsumed therein. For example, a stated range of “1.0 to 10.0” should be considered to include any and all subranges beginning with a minimum value of 1.0 or more and ending with a maximum value of 10.0 or less, e.g., 1.0 to 5.3, or 4.7 to 10.0, or 3.6 to 7.9.

[0064] All ranges disclosed herein are also to be considered to include the end points of the range, unless expressly stated otherwise. For example, a range of “between 5 and 10” or “5 to 10” or “5-10” should generally be considered to include the end points 5 and 10.

[0065] It is further to be understood that the feature or features of one embodiment may generally be applied to other embodiments, even though not specifically described or illustrated in such other embodiments, unless expressly prohibited by this disclosure or the nature of the relevant embodiments. Likewise, compositions and methods described herein can include any combination of features and/or steps described herein not inconsistent with the objectives of the present disclosure. Numerous modifications and/or adaptations of the compositions and methods described herein will be readily apparent to those skilled in the art without departing from the present subject matter.

Example

[0066] An example for a balm formulation is given below in Table 3.

TABLE-US-00003 TABLE 3 Example of a balm formulation The names of the raw materials are given using the International Nomenclature of Cosmetic Ingredients (INCI). The % are indicated by weight. % of component in INCI name of the final Function of component formulation the component OCTYLDODECANOL 17.00 Emollient CAPRYLIC/CAPRIC 14.70 Skin conditioning TRIGLYCERIDE RICINUS COMMUNIS 14.30 Emollient SEED OIL Skin conditioning ORYZA SATIVA CERA 14.00 Skin conditioning Skin protecting Smoothing RHUS VERNICIFLUA 13.40 Emollient PEEL CERA/RHUS Stabilising/ SUCCEDANEA FRUIT Binding CERA Emollient THEOBROMA CACAO 7.00 Emollient SEED BUTTER Skin conditioning PERSEA GRATISSIMA 5.00 Skin conditioning OIL CETEARYL ALCOHOL 3.00 Emollient Emulsifying Emulsion stabilising MYRISTYL MYRISTATE 3.00 Emollient Skin conditioning POLYGLYCERYL-3 2.50 Emulsifying DIISOSTEARATE CETYL ESTERS 2.00 Emollient Skin conditioning BUTYROSPERMUM 2.00 Emollient PARKII BUTTER Skin conditioning OLEYL ALCOHOL 0.48 Emollient Masking ZANTHOXYLUM 0.12 Skin conditioning BUNGEANUM FRUIT Skin soothing EXTRACT TOCOPHERYL ACETATE 0.50 Antioxidant MENTHYL ETHYLAMIDO 0.50 Cooling OXALATE Skin conditioning Eucalyptol Nat 0.2 Cooling Perfuming Skin conditioning MENTHOL 0.20 Cooling Refreshing Soothing BHT 0.10 Antioxidant

[0067] In this example, a balm was prepared by melting of the solid components in a water bath at a temperature sufficiently high to melt all ingredients, at about 60° C.-70° C. Subsequently, the liquid ingredients were added, and the mixture was stirred to form a bulk. Any volatile ingredients were added after letting the bulk cool under stirring, but whilst the bulk was still fluid. The fluid bulk was poured into a stainless steel mould with an array of recesses of hemispheric shape. Excess bulk was scraped off. The mould filled with the bulk was let cool down at 5° C. for 20 minutes. The solidified balm hemispheres were removed from the mould by turning it upside down and placing it on a hard surface. To produce the combination product, the balm was pressed on the base element (34, 34′) and the base element was assembled with the remaining parts of the balm holder element (30, 30″) and the container which contains the formulation for nasal administration.