TWO-PART PLASTIC BLANK SET

Abstract

The present invention relates to a two-part plastic blank set for the production of a drug applicator for storing a unit dose of a drug preparation and for administering that unit dose into the human nose.

Claims

1. A two-part plastic blank set, the plastic blank set comprising a bottom part and a lid part separate from the bottom part, the bottom part having a receiving space configuration enclosed by a sealing rim, and wherein an applicator tube integrally moulded on extends from the receiving space configuration and is sealed at its free end by a seal integrally moulded on via an attachment member, the attachment member having a wall thickness of 0.1-0.5 mm, and the lid part being of such a size as to completely cover the receiving space configuration of the bottom part when placed thereon, and having a sealing rim which can be sealingly joined to the sealing rim of the bottom part, wherein an attachment tab extending from the respective sealing rim, is moulded onto at least the lid part or the bottom part.

2. The two-part plastic blank set as claimed in claim 1, wherein at least the sealing rim of the lid part or the sealing rim of the bottom part is formed with grooves on a surface opposite the bottom part or the top part.

3. Two-part plastic blank set as claimed in claim 1, wherein the receiving space configuration has a shape of a spherical cap or spherical segment.

4. Two-part plastic blank set as claimed in claim 1, wherein the lid part is substantially flat in configuration.

5. Two-part plastic blank set as claimed in claim 1, wherein the plastic blank set is made from polyolefin.

6. The two-part plastic blank set as claimed in claim 5, wherein the polyolefin contains an inorganic additive.

7. The two-part plastic blank set as claimed in claim 6, wherein the inorganic additive is a pigment, preferably titanium dioxide (TiO.sub.2) surface-treated titanium dioxide or a mixture of the two.

8. A drug applicator which is manufactured by welding, the bottom part to the lid part of the the two-part plastic blank set as claimed in claim 1 via the respective sealing rims and which is filled with a drug formulation.

9. The drug applicator as claimed in claim 8 for use in the administration of the drug formulation contained in the drug applicator into the nose of a mammal.

10. The drug applicator as claimed in claim 9, wherein the administration is intended for the therapeutic or prophylactic treatment of the mammal.

11. The drug applicator as claimed in claim 8, wherein, after being dispensed from the drug applicator, the drug formulation forms a protective film against substances in the nose which are harmful to health.

12. The two-part plastic blank set as claimed in claim 1, wherein the bottom part, the lid part and the applicator tube have a wall thickness of at least 0.1 mm.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Further details of the invention will become clear from the following description and from the enclosed drawings. There,

[0032] FIG. 1 shows a perspective view of a two-part plastic blank set comprising a bottom part and a top part in accordance with the invention; and

[0033] FIG. 2 shows a drug applicator produced from a lid part and a bottom part in accordance with the invention in a perspective view.

DETAILED DESCRIPTION

[0034] FIG. 1 shows a perspective view of a two-part plastic blank set for the production of a drug applicator. The plastic blank set comprises a bottom part 2 and a lid part 3. The bottom part 2 has a receiving space configuration 12 which is enclosed by a sealing rim 5 and which is configured substantially in the shape of a spherical cup. Starting from the receiving space configuration 12, there extends an applicator tube 7 which is moulded on integrally, and which is sealed at its free end by a seal 14 likewise moulded on integrally via an attachment member 15. The size of the lid part 3 is such that it can completely cover the receiving space configuration 12 of the bottom part 2. The lid part 3 also has a peripheral sealing rim 6 which can be sealingly joined to the sealing rim 5 of the bottom part 2. The lid part 3 is configured to be substantially flat and has a sealing rim 6 with grooves 17 as means of directing energy in a specific direction.

[0035] Formed in the receiving space configuration 12 is a mouth 8, by means of which the applicator tube 7 leads into the receiving space configuration 12.

[0036] Both the bottom part 2 and the lid part 3 have attachment tabs 16, which extend in the same plane from the respective sealing rim. These attachment tabs may be printed on on their sides facing away from the other part, or may be provided with an adhesive label. In order to manufacture a drug applicator of the invention 1, as shown in FIG. 2, from the two-part plastic blank set of the invention, the bottom part 2 is filled with a drug in a suitable filling and sealing apparatus and then sealed with the lid part 3.

[0037] For this purpose, the bottom part can be placed in a filling and sealing apparatus, such as is known from EP 2 626 304 B1 for example. Unlike the procedure described there, using a one-part blank, the bottom part 2 is first inserted and filled in accordance with the present invention, and after the bottom part 2 has been filled, the lid part 3 is placed on the bottom part 2 in such a way that its sealing rim 6 comes to rest on the peripheral sealing rim 5 of the bottom part 2 running round the receiving space configuration 12. The presence of an attachment tab on the bottom part or top part ensures that it can be placed securely in a mount of the filling and sealing apparatus. The welding, preferably ultrasonic welding, is then carried out using routine methods known in the state of the art.

[0038] A drug applicator 1 produced in this way is shown in FIG. 2. The bottom part 2 and top part 3 together form a receiving space 4, in which a drug formulation is received.

[0039] For use, the seal 14 is first of all broken off, or twisted off, and removed via the attachment member 15. After that, the applicator tube 7 is introduced into a nostril, whereupon squeezing the receiving space configuration 12 with the finger and thumb forces the drug formulation stored in the receiving space 4 through the applicator tube 7 and into the nose. The attachment member 15 has a wall thickness in the range of 0.1-0.5 mm, preferably 0.2-0.3 mm.

[0040] The features of the invention disclosed in the above description and the claims can be essential both individually and in any combination to implementing the invention in its various embodiments.