CONCENTRATE COMPRISING A MEL, AN ALKYL POLYGLUCOSIDE AND MONOPROPYLENE GLYCOL

Abstract

The present invention relates to a concentrate comprising at least one lipid of mannosylerythritol (MEL), at least one alkypolyglucoside and monopropylene glycol, to the method for preparing same and to the uses thereof, in particular as an adjuvant.

Claims

1. A concentrate comprising: at least one mannosylerythritol lipid (MEL); at least one alkyl polyglucoside, and monopropylene glycol.

2. The concentrate according to claim 1, in which the at least one alkyl polyglucoside is a molecule of the following formula (III): ##STR00006## in which: n is an integer comprised between 0 and 5, R.sub.5 is an alkyl chain comprising between 5 and 20 carbon atoms.

3. The concentrate according to claim 1, in which the total quantity of alkyl polyglucoside(s) is comprised between 0.1 and 25% by weight with respect to the total weight of the concentrate.

4. The concentrate according to claim 1, in which the total quantity of MEL(s) is comprised between 0.1 and 25% by weight with respect to the total weight of the concentrate.

5. The concentrate according to claim 1, in which the quantity of monopropylene glycol is comprised between 75 and 99.8% by weight with respect to the total weight of the concentrate.

6. The concentrate according to claim 1, in which the monopropylene glycol:MEL(s) ratio and/or the monopropylene glycol:alkyl polyglucoside(s) ratio is/are comprised between 0.5 and 1000.

7. The concentrate according to claim 1, comprising at least two MELs selected from the group consisting of MEL-A, MEL-B, MEL-C and MEL-D.

8. The concentrate according to claim 1, further comprising at least one free fatty acid and/or at least one triglyceride.

9. A process for the preparation of a concentrate according to claim 1, comprising mixing at least one MEL with at least one alkyl polyglucoside and monopropylene glycol.

10. A phytosanitary composition comprising a concentrate according to claim 1, and a pesticide active ingredient.

11. A cosmetic composition comprising a concentrate according to claim 1, and a cosmetic active ingredient.

12. A solution comprising a concentrate according to claim 1 and water.

13. A process for the preparation of a solution claim 12, comprising mixing a concentrate according to claim 1 with water.

14. (canceled)

15. A solution comprising a phytosanitary composition according to claim 10 and water.

16. A solution comprising a cosmetic composition according to claim 11 and water.

17. A process for the preparation of a solution, comprising mixing a phytosanitary composition according to claim 10 with water.

18. A process for the preparation of a solution, comprising mixing a cosmetic composition according to claim 11 with water.

Description

[0154] The invention will be better understood in light of the examples which follow, given by way of illustration, with reference to the following figures:

[0155] FIG. 1, which represents the contact angle formed by the tangent to a drop of liquid 1 at the point of contact with a flat solid surface 2;

[0156] FIG. 2, which represents three cases in point showing the idea of wetting, namely the case of a total wetting of a flat solid surface 2 by a drop of liquid 1 (FIG. 2a), the case of a partial wetting of a flat solid surface 2 by a drop of liquid 1 (FIG. 2b) and the case where a drop of liquid 1 does not wet a flat solid surface 2 (FIG. 2c);

[0157] FIG. 3, which is a diagram representing the reduction in the contact angle obtained with a solution comprising the concentrate according to the invention and solutions comprising comparative concentrates.

EXAMPLE 1; PREPARATION OF A CONCENTRATE ACCORDING TO THE INVENTION

[0158] 1. Obtaining the MELs

[0159] The MELs were obtained by a fermentation process comprising the following steps: [0160] culturing a yeast strain such as Pseudozyma aphidis in the presence of vegetable oil (rapeseed) in order to obtain the MELs; and [0161] recovering the MELs thus obtained.

[0162] At the end of the step of recovering the MELs, a mixture of MELs is obtained which has the following characteristics: [0163] Content of MELs: 55% by weight [0164] Content of other components: 45% by weight (of which 42% by weight of free fatty acids and triglycerides and 3% by weight of water and strain),
the percentages by weight being given with respect to the total weight of the mixture of MELs obtained.

[0165] 2. Alkyl Polyglucosides

[0166] Simulsol SL11W from Seppic was used. Simulsol SL11W is mainly composed (approximately 40 to 60% by weight) of alkyl polyglucosides of the following formula (IV):

##STR00005##

[0167] 3. Monopropylene Glycol

Monopropylene glycol from OLEON marketed under the trademark RADIA 4713 was used.

[0168] 4. Process for the Preparation of the Concentrate According to the Invention

[0169] 5% by weight of the mixture of MELs, 5% by weight of Simulsol S11W and 90% by weight of monopropylene glycol were added to a 60-mL glass flask, the percentages by weight being indicated with respect to the total weight of the concentrate obtained, and then stirred manually until homogenization of the concentrate was achieved. During stirring, it is possible to heat the concentrate at 40 C. in order to facilitate the homogenization.

EXAMPLE 2 EVALUATION OF THE WETTING POWER OF A SOLUTION COMPRISING THE CONCENTRATE ACCORDING TO THE INVENTION AND OF SOLUTIONS COMPRISING COMPARATIVE CONCENTRATESSYNERGISTIC EFFECT

[0170] In order to evaluate the effect of the concentrate according to the invention on the wetting power of a solution, an aqueous solution comprising the concentrate according to the invention and aqueous solutions comprising comparative concentrates were prepared. Measurements of the contact angle of the aqueous solutions obtained were then carried out.

[0171] 1. Materials and Methods

[0172] 1.1 Materials

[0173] The following products were used in this Example: [0174] monopropylene glycol (RADIANOL 4713, OLEON) [0175] alkyl polyglucosides (Simulsol SL11W) [0176] the mixture of MELs prepared in Example 1 [0177] the concentrate according to the invention prepared in Example 1 [0178] hard water (hardness equal to 500 ppm)

[0179] The following equipment was also used in this Example: [0180] glass bottles, [0181] 1-mL syringes equipped with a needle with a diameter of 0.63 mm [0182] hydrophobic parafilms (Parafilm M, NEENAH, Wis. 54956) [0183] the DSA10 goniometer (KRUSS) [0184] the Drop shape analysis software (KRUSS)

[0185] 1.2. Methods

[0186] Preparation of the Aqueous Solution Comprising the Concentrate According to the Invention

[0187] 0.500% by weight of the concentrate according to the invention was added to 99.500% by weight of water in a glass flask, the percentages by weight being indicated with respect to the total weight of the solution obtained, and then stirred manually until homogenization of the solution was achieved.

[0188] Preparation of the Aqueous Solutions Comprising Comparative Concentrates

[0189] Comparative Solution 2

[0190] 0.450% by weight of monopropylene glycol was added to 99.550% by weight of water in a glass flask, the percentages by weight being indicated with respect to the total weight of the solution obtained, and then stirred manually until homogenization of the solution was achieved.

[0191] Comparative Solution 3

[0192] 0.025% by weight of the mixture of MELs 1 was added to 99.975% by weight of water in a glass flask, the percentages by weight being indicated with respect to the total weight of the solution obtained, and then stirred manually until homogenization of the solution was achieved.

[0193] Comparative Solution 4

[0194] 0.025% by weight of Simulsol SL11W was added to 99.975% by weight of water in a glass flask, the percentages by weight being indicated with respect to the total weight of the solution obtained, and then stirred manually until homogenization of the solution was achieved.

[0195] Comparative Solution 5

[0196] 0.025% by weight of Simulsol SL11W and 0.025% by weight of the mixture of MELs 1 were added to 99.950% by weight of water in a glass flask, the percentages by weight being indicated with respect to the total weight of the solution obtained, and then stirred manually until homogenization of the solution was achieved.

[0197] Comparative Solution 6

[0198] 0.025% by weight of the mixture of MELs 1 and 0.475% by weight of MPG were added to 99.5% by weight of water in a glass flask, the percentages by weight being indicated with respect to the total weight of the solution obtained, and then stirred manually until homogenization of the solution.

[0199] Comparative Solution 7

[0200] 0.025% by weight of Simulsol SL11W and 0.475% by weight of monopropylene glycol were added to 99.5% by weight of water in a glass flask, the percentages by weight being indicated with respect to the total weight of the solution obtained, and then stirred manually until homogenization of the solution was achieved.

[0201] The various solutions prepared are summarized below in Table 1:

TABLE-US-00001 TABLE 1 Solutions prepared in Example 2. Solution 1 Concentrate according to the invention + water Comparative solution 2 Monopropylene glycol + water Comparative solution 3 Mixture of MELs + water Comparative solution 4 Simulsol SL11W + water Comparative solution 5 Simulsol SL11W + Mixture of MELs 1 + water Comparative solution 6 Mixture of MELs + Monopropylene glycol + water Comparative solution 7 Simulsol SL11W + Monopropylene glycol + water

[0202] A control solution only comprising water was also prepared.

[0203] Measurement of the Contact Angles

[0204] Contact angle measurements were carried out for each of solutions 1 to 7 and the control solution, using the goniometer.

[0205] To this end, a drop of each emulsion and of the control solution (3 L) was formed using the syringe. The syringe was then placed approximately 0.5 cm above the hydrophobic parafilm. By gravity, this drop became detached from the needle and fell onto the hydrophobic parafilm. The variation in the contact angle was monitored for 10 minutes from the moment when the drop touched the parafilm, using the analysis software.

[0206] The results were then processed in order to compare the variations in contact angles for each of solutions 1 to 7, with respect to the control solution.

[0207] 2. Results

[0208] The results of the contact angle measurements for each of solutions 1 to 7 and for the control solution are presented in FIG. 3.

[0209] The results show that the reduction in the contact angle obtained with solution 1 is greater than that obtained with each of solutions 2 to 7. Solution 1, comprising the concentrate according to the invention, therefore has greater wetting power than solutions 2 to 7 comprising comparative concentrates.

[0210] Thus, a solution comprising the concentrate according to the invention, i.e. comprising a combination of at least one alkyl polyglucoside, at least one MEL and monopropylene glycol, has greater wetting power than a solution comprising one, or a combination of two of these three components.

[0211] In particular, the addition of monopropylene glycol to the mixture of MELs (comparative solution 6), or the addition of monopropylene glycol to Simulsol SL11W (comparative solution 7) does not have any positive effect on the reduction in contact angle, with respect to the reductions in contact angle obtained with the mixture of MELs alone (comparative solution 3) or Simulsol SL11W alone (comparative solution 4).

[0212] Now, surprisingly, the combination of monopropylene glycol, mixture of MELs and Simulsol SL11W (solution 1) results in a reduction in the contact angle greater than that obtained with the mixture of MELs alone (comparative solution 3), Simulsol SL11W alone (comparative solution 4), and more particularly with the mixture of MELs combined with Simulsol SL11W (comparative solution 5).

[0213] Thus, surprisingly, when monopropylene glycol is added to a solution comprising at least one alkyl polyglucoside and at least one MEL, so that the solution comprises the concentrate according to the invention, the wetting power of said solution is increased considerably.

[0214] Surprisingly, the results presented in FIG. 3 show that the reduction in the contact angle obtained with solution 1 comprising the concentrate according to the invention (monopropylene glycol, mixture of MELs, Simulsol SL11W) is greater than the sum of the reductions obtained with comparative solution 2 (comprising monopropylene glycol) and comparative solution 5 (comprising the mixture of MELs and Simulsol SL11W). This synergistic effect is particularly evident at the moment when the drop is deposited on the hydrophobic film (T0), as shown in Table 2 below.

TABLE-US-00002 TABLE 2 Synergy observed between the components of the concentrate according to the invention at T0 Control Solution Solution Solution solution 2 5 1 Contact angle at T0 () 107.8 107.9 84.9 77.5

[0215] Thus, when a drop of a solution comprising the concentrate according to the invention is deposited on a hydrophobic surface, such as a leaf, it spreads more effectively over the leaf at the moment of impact and is therefore less likely to bounce and land outside of said leaf. This is particularly advantageous when spraying phytosanitary solutions.

EXAMPLE 3: USE OF CONCENTRATE ACCORDING TO THE INVENTION IN THE PREPARATION OF A PHYTOSANITARY COMPOSITIONPREPARATION OF A SOLUTION

[0216] A concentrate according to the invention was prepared, then used in the preparation of a phytosanitary composition.

[0217] The concentrate according to the invention has the following characteristics:

TABLE-US-00003 Components % by weight* Alkyl polyglucosides 6 Mixture of MELs 8 Monopropylene glycol 86 *Percentage by weight with respect to the total weight of the concentrate

[0218] A phytosanitary composition was then prepared, by mixing the concentrate according to the invention with cinnamaldehyde. The phytosanitary composition according to the invention obtained has the following characteristics:

TABLE-US-00004 Components % by weight* Concentrate according to the invention 90 Cinnamaldehyde (Herbarom Laboratory) 10 *Percentage by weight with respect to the total weight of the phytosanitary composition

[0219] A solution was then prepared from the phytosanitary composition according to the invention obtained, as follows:

[0220] 50% by weight of water, 1% by weight of the phytosanitary composition according to the invention and then 49% by weight of water were successively added into a resealable container, the percentages by weight being indicated with respect to the total weight of the solution obtained. If necessary, the pH and the salinity of the water will have been adjusted beforehand.

[0221] The solution according to the invention obtained has the following characteristics:

TABLE-US-00005 Components % by weight* Phytosanitary composition 1 according to the invention water 99 *Percentage by weight with respect to the total weight of the solution

EXAMPLE 4: USE OF A CONCENTRATE ACCORDING TO THE INVENTION IN THE PREPARATION OF A COSMETIC COMPOSITION PREPARATION OF A SOLUTION

[0222] A concentrate according to the invention was prepared, then used in the preparation of a cosmetic composition.

[0223] The concentrate according to the invention has the following characteristics:

TABLE-US-00006 Components % by weight* Alkyl polyglucosides 8 Mixture of MELs 8 Monopropylene glycol 84 *Percentage by weight with respect to the total weight of the concentrate

[0224] A cosmetic composition was then prepared by mixing the concentrate according to the invention with a linseed extract. The cosmetic composition according to the invention obtained is a firming composition for the face, which has the following characteristics:

TABLE-US-00007 Components % by weight* Concentrate according to the invention 90 Linseed extract (Aroma-zone) 10 *Percentage by weight with respect to the total weight of the cosmetic composition

[0225] A solution was then prepared from the cosmetic composition according to the invention obtained, as follows:

[0226] 5% by weight of the cosmetic composition according to the invention was added to 95% by weight of water in a flask, the percentages by weight being indicated with respect to the total weight of the cosmetic solution obtained. If necessary, the pH and the salinity of the water will have been adjusted beforehand.

[0227] The firming solution for the face according to the invention obtained has the following characteristics:

TABLE-US-00008 Components % by weight* Cosmetic composition 5 according to the invention Water 95 *Percentage by weight with respect to the total weight of the solution
Other components may be added to this solution, such as other cosmetic active ingredients and/or formulation agents.