FILTER SKID WITH TILTING MECHANISM

Abstract

A filtration system (1) has a filtration unit (2) with at least one filter element (4) for filtration of a fluid. The at least one filter element (4) has a main flow direction (C) for the fluid. The filtration unit (2) is configured to tilt the at least one filter element (4) around a tilting axis (B) to change an orientation of the main flow direction (C). A main unit (3) is fluidly connectable to the filtration unit (2) and includes a supply unit (18) configured to supply the fluid to the at least one filter element (4). A control unit is configured to control supplying and/or evacuating the fluid to/from the at least one filter element (4) and to control tilting of the at least one filter element (4) around the tilting axis (B).

Claims

1. A filtration system (1) comprising: a filtration unit (2) comprising at least one filter element (4) for filtration of a fluid, the at least one filter element (4) having a main flow direction (C) for the fluid, and wherein the filtration unit (2) is configured to tilt the at least one filter element (4) around a tilting axis (B) to change an orientation of the main flow direction (C); a main unit (3) fluidly connectable to the filtration unit (2), the main unit comprising: a supply unit (18) configured to supply the fluid to the at least one filter element (4); and a control unit configured to control supplying and/or evacuating the fluid to/from the at least one filter element (4) and to control tilting of the at least one filter element (4) around the tilting axis (B).

2. The filtration system (1) of claim 1, wherein the filtration unit (2) is fluidly connected to the main unit (3) with a flexible connection (15) in a closed manner.

3. The filtration system (1) of claim 1, wherein the filtration unit comprises a tilting frame (5) configured to carry the at least one filter element (4), the tilting frame (5) being tiltable around the tilting axis (B).

4. The filtration system (1) of claim 3, wherein the filtration unit (2) comprises a main frame (6) configured to support the tilting frame (5), the tilting frame (5) being configured to be tiltable with respect to the main frame (6).

5. The filtration system (1) of claim 1, wherein the control unit is configured to tilt the at least one filter element (4) around the tilting axis to change the orientation of the main flow direction (C) between a first orientation and a second orientation, and wherein the first orientation may be a horizontal orientation and the second orientation may be a vertical orientation.

6. The filtration system (1) of claim 5, wherein the control unit is configured, for a test phase and/or for a recovery phase and/or for a draining phase, to tilt the at least one filter element (4) around the tilting axis (B) to change the orientation of the main flow direction (C) into the first orientation.

7. The filtration system (1) of claim 5, wherein the control unit is configured, for a filtration phase, to tilt the at least one filter element (4) around the tilting axis (B) to change the orientation of the main flow direction (C) into an orientation between the first orientation and the second orientation.

8. The filtration system (1) of claim 1, wherein the control unit is configured to control an inlet valve (16) and an outlet valve (17), the inlet valve (16) and the outlet valve (17) being associated to the at least one filter element (4).

9. The filtration system (1) of claim 1, wherein the at least one filter element (4) comprises a first filter element (4a) and a second filter element (4b), and wherein the control unit is configured to supplying the fluid to the first filter element (4a) and the second filter element (4b) successively and/or simultaneously, and/or wherein the control unit is configured to evacuating the fluid from the first filter element (4a) and the second filter element (4b) successively and/or simultaneously.

10. A filtration method for filtering of a fluid, the method comprising: providing at least one filter element (4), the at least one filter element (4) having a main flow direction (C) for the fluid, and wherein the at least one filter element (4) is tiltable around a tilting axis (B) to change an orientation of the main flow direction (C); supplying the fluid to be filtered to the at least one filter element (4); tilting the at least one filter element (4) around the tilting axis (B) to change the orientation of the main flow direction (C); and filtering the fluid to be filtered by the at least one filter element (4).

11. The filtration method of claim 10, further comprising: turning the at least one filter element (4) around the tilting axis (B) to change the orientation of the main flow direction (C); and recovering the filtered fluid from the at least one filter element (4).

12. The filtration method of claim 11, further comprising: turning the at least one filter element (4) around the tilting axis (B) to change the orientation of the main flow direction; and testing the at least one filter element (4).

13. The filtration method of claim 10, further comprising: turning the at least one filter element (4) around the tilting axis (B) to change the orientation of the main flow direction; and testing the at least one filter element (4).

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0040] FIG. 1 shows exemplary filtration system.

[0041] FIG. 2 is a perspective view of an exemplary filtration system in a first disposition.

[0042] FIG. 3 is a perspective view of an exemplary filtration system in a second disposition.

[0043] FIG. 4 is a schematic illustration of an exemplary filter element.

[0044] FIG. 5 is a flowchart of an exemplary filtration process.

[0045] FIGS. 6a and 6b show a first example for using the filtration system.

[0046] FIGS. 7a and 7b show a second example for using the filtration system.

[0047] FIGS. 8a and 8b show a third example for using the filtration system.

DETAILED DESCRIPTION

[0048] The figures are schematic representations, which are not up to scale and which may comprise parts that are enlarged or downsized for a better understanding. Further, some parts may be omitted for better understanding.

[0049] In the following, a filtration system according to the present disclosure is described with reference to FIGS. 1 to 3. FIGS. 1 to 3 show a filtration system 1. The filtration system 1 comprises a filtration unit 2 and a main unit 3. The filtration unit 2 comprises at least one filter element 4, a tilting frame 5 and a main frame 6. As shown in FIG. 1, the main frame 6 is provided below the tilting frame 5 and the main frame 6 is configured to support the tilting frame 5. The main frame 6 may comprise a frame structure 7 having two support elements 8 and 9 as shown in FIGS. 2 and 3. The two support elements 8 and 9 are arranged parallel to each other and extend horizontally, i.e. perpendicular to the force of gravity, so that the support elements 8 and 9 generate a horizontal plane. For example, the support elements 8 and 9 extend parallel to a horizontal axis A. Each of the support elements 8 and 9 may comprise a bearing 10 and 11 for connecting the tilting frame 5 to the main frame 6. The bearings 10 and 11 may be ball bearings. An axis extending through the bearings 10 and 11 may represent a tilting axis B. The tilting frame 5 may be configured to tilt around the tilting axis B. The at least one filter element 4 is arranged in the tilting frame 5 and may tilt around the tilting axis B when the tilting frame 5 is tilted around the tilting axis B. To tilt the tilting frame 5, the filtration unit 2 comprises at least one actuator 12 connecting the tilting frame 5 and the main frame 6. For example, the at least one actuator 12 may be a hydraulic actuator, pneumatic or an electromechanical actuator.

[0050] The at least one filter element 4 may be connected to a conduit arrangement 13 of the tilting frame 5 for supplying the at least one filter element 4 with a fluid. The conduit arrangement 13 may be configured to carry the at least one filter element 4. The conduit arrangement 13 of the tilting frame 5 may be fluidly connected via conduit element 15 to a conduit arrangement 14 of the main unit 3. The conduit element 15 may be provided as a flexible conduit element, so that the main unit 3 and the filtration unit 2 may be positioned flexibly to each other. Preferably, the conduit arrangement 13 may fluidly connect the tilting frame 5 and the main unit 3 in a closed manner thereby maintaining the sterility of the system which is essential for filtration processes of biologicals. For example, the conduit element 15 may be a plastic tube or any other suitable connection. The at least one filter element 4 may be connected to the conduit arrangement 13 of the tilting frame 5 via an inlet valve 16 and an outlet valve 17.

[0051] Furthermore, the at least one filter element 4 comprises a main flow direction C of the fluid. The main flow direction C may correspond to a flow direction of the fluid through the at least one filter element 4 when the fluid flows from the inlet valve 16 towards the outlet valve 17. As shown in FIG. 1, the main flow direction C has a vertical orientation being directed opposite to the force of gravity. When tilting the tilting frame 5 around the tilting axis B, the orientation of the main flow direction C is changed. For example, as shown in FIG. 3 the orientation of the main flow direction C is changed to a horizontal orientation, the horizontal orientation may be parallel to the horizontal axis A.

[0052] The main unit 3 may further comprise a supply unit 18 for supplying the fluid to the at least one filter element 4. For example, the supply unit 18 may comprise a pump 19 fluidly connected to the conduit arrangement 14 of the main unit 3. The pump 19 may be configured to pump the fluid to the at least one filter element 4 for supplying and/or evacuating the fluid to/from the at least one filter element 4. Furthermore, the main unit 3 may comprise a control unit (not shown) configured to control supplying and/or evacuating the fluid to/from the at least one filter element 4 and to control tilting of the at least one filter element 4 around tilting axis B. In particular, the control unit may be configured to control the inlet valve 16, the outlet valve 17 and the pump 19 in such a manner to supply/evacuate the fluid to/from the at least one filter element 4. Furthermore, the at least one filter element 4 may be connected to a venting valve 20 for venting the at least one filter element 4. The control unit may also be configured to control the venting valve 20.

[0053] The main unit 3 and the filtration unit 2 are movable. For example, wheels 29 are provided on the bottom of the main unit 3 and the filtration unit 2 so that the main unit 3 and the filtration unit 2 can be flexibly positioned with respect to each other. Furthermore, the main unit 3 and the filtration unit 2 are configured to be securely positioned on an installation site. For example, securing elements 30 may be provided on the bottom of the main unit 3 and the filtration unit 2 for securing the main unit 3 and the filtration unit 2 at the installation site. For example, the securing elements 30 may comprise height adjustable stands for securing the main unit 3 and the filtration unit 2 at the installation site.

[0054] Additionally, the filtration unit 2 may be provided with a motion sensor 28. The motion sensor 28 is configured to detect obstacles within the working area of the filtration unit 2. If it is detected that obstacles are within the working area of the filtration unit 2, tilting of the tilting frame 4 is prevented. Thus, it is possible to prevent that an operator is injured when the tilting frame 4 is tilted around the tilting axis.

[0055] Furthermore, the at least one filter element 4 may comprise a first filter element 4a and a second filter element 4b. Each of the first filter element 4a and the second filter element 4b is connected to the conduit arrangement 13 of the filtration unit 2 via a respective inlet valve 16, a respective outlet valve 17 and a respective venting valve 20. Furthermore, the control unit may be configured to supply/evacuate the fluid to/from the first filter element 4a and the second filter element 4b successively and/or in parallel by appropriately operating the respective inlet valve 16, outlet valve 17 and venting valve 20.

[0056] FIG. 4 shows an exemplary filter element 4. The filter element 4 may have a cylindrical wall 21. The cylindrical wall 21 extends along the main flow direction C. Furthermore, the filter element 4 may have a first port 22 associated to the inlet valve 16, a second port 23 associated to the outlet valve 17 and a third port 24 associated with the venting valve 20. The fluid may enter the at least on filter element 4 through the first port 22 and the fluid may be taken out of the at least one filter element 4 through second port 23. The main flow direction C may correspond to the flow of the fluid through the filter element 4 when the fluid is flowing from the first port 22 to the second port 23. For example, the filter element may be a hollow fibre filter. However, the disclosure is not limited to hollow fibre filters and any other type of filter medium may be used.

[0057] FIG. 5 shows an exemplary filtration process of a fluid according to the present disclosure. The filtration process will be described with reference to FIGS. 6a to 8b. The exemplary filtration process comprises a preparation step S1, a cleaning step S2, a draining step S3, a testing step S4 and a filtration step S5. However, the filtration process may comprise further steps.

[0058] During the preparation step S1, the at least one filter element 4 is inserted into the tilting frame 5 and connected to the conduit arrangement 13 of the filtration unit 2. Furthermore, the main unit 3 is fluidly connected to the filtration unit 2 via the conduit element 15. After the preparation step S1 is finished, the filtration system 1 may undergo a pressure hold test. The pressure hold test is performed to verify that no leaks exist in the filtration system 1, i.e. that the filtration system 1 is leak-proof. During the pressure hold test, the at least one filter element 4 is tilted around the tilting axis B in a position so that the main flow direction C is in a vertical orientation. The vertical orientation is perpendicular to the horizontal plane and is directed opposite to the force of gravity.

[0059] When it is verified that the filtration system 1 is leak-proof, the filtration system 1 may be cleaned in cleaning step S2. During the cleaning step S2, the at least one filter element 4 may be tilted around the tilting axis into a position so that the main flow direction C is in the vertical orientation. If the main flow direction C is already in the vertical orientation, the tilting of the at least one filter element 4 is skipped. During the cleaning step S2, a suitable cleaning fluid is supplied to the at least one filter element 4. For example, a cleaning fluid may comprise NaOH or water for injection (WFI).

[0060] After the cleaning step S2 has been completed, the draining step S3 is carried out. The at least one filter element 4 is tilted around the tilting axis B so that the orientation of the main flow direction C is changed from a vertical orientation (FIG. 6a) into the horizontal orientation (FIG. 6b). By tilting the at least one filter element 4 around the tilting axis B so that the main flow direction C has the horizontal orientation, the cleaning fluid remaining in the at least one filter element 4 can be easier evacuated from the at least one filter element 4. Due to the gravity, the cleaning fluid can be easier evacuated through the second port 23.

[0061] During testing step S4, an integrity test step of the at least one filter element 4 may be performed. For the integrity test step, the at least one filter element 4 may be tilted around the tilting axis B so that the orientation of the main flow direction C changes from a vertical orientation (FIG. 7a) into the horizontal orientation (FIG. 7b). Furthermore, the at least one filter element 4 is filled with a liquid and pressurised air is provided to the at least one filter element 4 via the first port 22. As shown in FIG. 7b, due to the horizontal orientation of the main flow direction C, small gas or air bubbles 25 ascend inside the at least one filter element 4 towards a part of the wall 21 facing up, i.e. away from the installation site. Furthermore, a large gas or air bubble 26 formed by the fusion of multiple small gas or air bubbles 25, which individually may be difficult to observe with the large air bubble 26, ascends inside the at least one filter element 4 towards a part of the wall 21 facing up. This allows a better visual inspection of the at least one filter element 4.

[0062] When the filtration system 1 has been drained and tested, a filtration step S5 may be carried out which is explained with reference to FIG. 8a and FIG. 8b. During the filtration step S5, a liquid 27 to be filtered is provided to the at least one filter element 4 via the first port 22 and the at least one filter element 4 is filled with the liquid 27. Furthermore, the liquid 27 can be removed from the at least one filter element number 4 via the second port 23 when the fluid 27 reaches a sufficient level inside the at least one filter element 4. However, in the upper area of the at least one filter element 4 air bubbles 25 may occur causing a reduced effective filter area of the at least one filter element 4. Thus, during the filtration step S5, the at least one filter element 4 is tilted around the tilting axis B into a position so that the main flow direction C is between the horizontal orientation and the vertical orientation. For example, an tilting angle between the main flow direction and the horizontal axis A may be between 0 and 90, preferably between 30 and 60 and more preferably 45. However, depending upon the type and design of the at least one filter element 4, a tilting angle greater than 90 may be advantageous. When tilting the at least one filter element 4 in such a manner and thereby changing the orientation of the main flow direction, the area for air bubbles 25 inside the at least one filter element number 4 is reduced. Consequently, the effective filter area of the at least one filter element 4 is increased. This leads to a faster filtration processing, reduced cost and less waste.

REFERENCE SIGNS

[0063] 1 filtration system [0064] 2 filtration unit [0065] 3 main unit [0066] 4 at least one filter element [0067] 4a first filter element [0068] 4b second filter element [0069] 5 tilting frame [0070] 6 main frame [0071] 7 frame structure [0072] 8, 9 support elements [0073] 10, 11 bearings [0074] 12 actuator [0075] 13 conduit arrangement (of the filtration unit) [0076] 14 conduit arrangement (of the main unit) [0077] 15 conduit element [0078] 16 inlet valve [0079] 17 outlet valve [0080] 18 supply unit [0081] 19 pump [0082] 20 venting valve [0083] 21 wall [0084] 22 first port [0085] 23 second port [0086] 24 third port [0087] 25 air bubbles [0088] 26 large air bubble [0089] 27 liquid [0090] 28 motion sensor [0091] 29 wheels [0092] 30 securing elements [0093] A horizontal axis [0094] B tilting axis [0095] C main flow direction