Penflufen as a wood preservative against wood-destroying basidiomycetes

Abstract

The invention relates to the use of penflufen for protecting wood and wood-comprising materials against wood-destroying basidiomycetes.

Claims

1. A process for protecting wood and wood-comprising materials against attack or destruction by wood-destroying basidiomycetes, the process comprising treating a wood or wood-comprising material with a treatment solution comprising at least one diluent or solvent, and 0.001% to 5% by weight biocidal compounds comprising 65-55% by weight of at least one of penflufen and salts thereof, and 35-45% by weight of copper oxide, and the treatment solution has an efficacy of greater than 99% against wood destroying basidiomycetes.

2. The process according to claim 1 wherein: the basidiomycetes comprise holobasidiomycetes; and the treating comprises treating the wood or wood-comprising material by at least one of painting, spraying, drenching, submersion, and impregnation of the wood or wood-comprising material with the treatment solution.

Description

EXAMPLES

Example 1

Inhibition Test with Giant Colonies of Wood-destroying Basidiomycetes

(1) Mycelium pieces were punched out of colonies of Coniophora puteana, Poria placenta, Lentinus tigrinus, Coriolus versicolor and Gloeophyllum trabeum and incubated on an agar nutrient soil at 26 C. The inhibition of the growth of the hyphae on active compound-comprising nutrient soil was compared to the longitudinal growth without addition of active compound and rated as inhibition in percent (incubation time: about 1 week, depending on the fungal growth of the comparative sample without active compound). The active compound concentration was 1 ppm.

(2) TABLE-US-00001 (I) (II) (III) Inhibition [%] No. Fungus I II III 1 Coniophora puteana 100 12 25 2 Coriolus versicolor 100 15 78 3 Lentinus tigrinus 100 17 37 4 Poria placenta 100 3 45 5 Gloeophyllum trabeum 100 11 18

(3) Penflufen (I) acts markedly better against wood-destroying basidiomycetes than (II) and (III).

Example 2

Synergism Tests

(4) Mycelium pieces were punched out of a colony of the wood-destroying fungus in question and incubated on a malt extract/peptone-containing nutrient agar at 26 C. The growth of the hyphae with and without active compound was compared. The minimum inhibitory concentration (MIC) stated was the concentration at which the radial hyphae growth was suppressed completely.

(5) The synergism was determined using the method described by Kull et al. (F. C. Kull, P. C. Eismann, H. D. Sylvestrowicz, R. L. Mayer, Applied Microbiology 1961, 9, 538-541). The following relationships apply:

(6) $\frac{Q_A}{Q_a}+\frac{Q_B}{Q_b}=\mathrm{SI}$ SI=1 means additivity SI>1 means antagonism SI<1 means synergism Q.sub.a=concentration of substance A which is the MIC Q.sub.b=concentration of substance B which is the MIC Q.sub.A=concentration of substance A in the concentration of A/B at which microbial growth is suppressed Q.sub.B=concentration of substance A in the concentration of A/B at which microbial growth is suppressed

(7) 2.1 Combinations of Penflufen and Thiabendazole against the Wood-destroying Organism Coriolus versicolor

(8) TABLE-US-00002 MIC against Coriolus versicolor (ppm) SI penflufen 0.3 penflufen:thiabendazole 9:1 0.3 0.91 penflufen:thiabendazole 3:2 0.3 0.64 penflufen:thiabendazole 1:1 0.5 0.92 penflufen:thiabendazole 2:3 0.5 0.77 thiabendazole 3.0

(9) 2.2 Combinations of Penflufen and Fenpropimorph against the Wood-destroying Organisms Coniophora puteana and Lentinus tigrinus

(10) TABLE-US-00003 MIC (ppm) SI Coniophora Lentinus Coniophora Lentinus puteana tigrinus puteana tigrinus penflufen 1.0 0.5 penflufen:fenpropimorph 7:3 0.7 0.5 0.50 0.71 penflufen:fenpropimorph 6:4 1.0 0.5 0.61 0.61 penflufen:fenpropimorph 1:1 0.7 0.7 0.36 0.71 penflufen:fenpropimorph 4:6 0.7 0.7 0.29 0.57 penflufen:fenpropimorph 3:7 0.7 0.7 0.23 0.44 penflufen:fenpropimorph 2:8 0.5 0.5 0.11 0.21 penflufen:fenpropimorph 1:9 0.7 3.0 0.09 0.69 fenpropimorph 30 30

(11) 2.3 Combinations of Penflufen and Copper(II) Oxide against the Wood-destroying Organism Gloeophyllum trabeum

(12) TABLE-US-00004 MIC against Gloeophyllum trabeum (ppm) SI penflufen 0.3 penflufen:copper(II) oxide 7:3 0.3 0.70 penflufen:copper(II) oxide 6:4 0.1 0.20 penflufen:copper(II) oxide 1:1 0.3 0.50 penflufen:copper(II) oxide 4:6 0.5 0.67 penflufen:copper(II) oxide 3:7 0.5 0.50 penflufen:copper(II) oxide 2:8 1.0 0.67 copper(II) oxide 100.0

(13) 2.4 Combinations of Penflufen and Tebuconazole against the Wood-destroying Organism Stereum sanguinolentum

(14) TABLE-US-00005 MIC against Stereum sanguinolentum (ppm) SI penflufen 3.0 penflufen:tebuconazole 6:4 1.0 0.27 penflufen:tebuconazole 1:1 3.0 0.75 penflufen:tebuconazole 4:6 0.7 0.16 penflufen:tebuconazole 3:7 0.5 0.11 penflufen:tebuconazole 2:8 0.5 0.10 penflufen:tebuconazole 1:9 1.0 0.18 tebuconazole 6.0

(15) 2.5 Combinations of Penflufen and Propiconazole against the Wood-destroying Organism Coniophora puteana

(16) TABLE-US-00006 MIC against Coniophora puteana (ppm) SI penflufen 3.0 penflufen:propiconazole 9:1 1.0 0.33 penflufen:propiconazole 8:2 0.5 0.17 penflufen:propiconazole 7:3 0.5 0.17 penflufen:propiconazole 6:4 0.5 0.17 penflufen:propiconazole 1:1 0.5 0.17 penflufen:propiconazole 4:6 0.5 0.17 penflufen:propiconazole 3:7 0.3 0.10 penflufen:propiconazole 2:8 0.5 0.17 penflufen:propiconazole 1:9 0.5 0.17 propiconazole 3.0

(17) 2.6 Combinations of Penflufen and Permethrin against the Wood-destroying Organism Poria placenta

(18) TABLE-US-00007 MIC against Poria placenta (ppm) SI penflufen 0.1 penflufen:permethrin 7:3 0.1 0.70 penflufen:permethrin 6:4 0.1 0.60 penflufen:permethrin 1:1 0.1 0.50 penflufen:permethrin 4:6 0.1 0.40 permethrin >100

(19) 2.7 Combinations of Penflufen and Etofenprox against the Wood-destroying Organism Poria placenta

(20) TABLE-US-00008 MIC against Poria placenta (ppm) SI penflufen 0.1 penflufen:etofenprox 7:3 0.1 0.70 penflufen:etofenprox 6:4 0.1 0.60 penflufen:etofenprox 1:1 0.1 0.50 penflufen:etofenprox 4:6 0.1 0.40 penflufen:etofenprox 3:7 0.1 0.30 penflufen:etofenprox 2:8 0.3 0.60 penflufen:etofenprox 1:9 0.1 0.10 etofenprox >100

(21) 2.8 Combinations of Penflufen and Prochloraz against the Wood-destroying Organisms Coniophora puteana and Lentinus tigrinus

(22) TABLE-US-00009 MIC (ppm) SI Coniophora Lentinus Coniophora Coniophora puteana tigrinus puteana puteana penflufen 3.0 0.3 penflufen:prochloraz 3:7 0.3 0.5 0.04 0.52 penflufen:prochloraz 2:8 0.3 1.0 0.03 0.71 penflufen:prochloraz 1:9 1.0 1.0 0.06 0.38 prochloraz >30 20

(23) 2.9 Combinations of Penflufen and Bifenthrin against the Wood-destroying Organism Coriolus versicolor

(24) TABLE-US-00010 MIC against Coriolus versicolor (ppm) SI penflufen 0.1 penflufen:bifenthrin 4:6 0.1 0.40 penflufen:bifenthrin 3:7 0.1 0.30 penflufen:bifenthrin 2:8 0.3 0.60 penflufen:bifenthrin 1:9 0.1 0.10 bifenthrin 60.0

(25) 2.10 Combinations of Penflufen and Cypermethrin against the Wood-destroying Organisms Coriolus versicolor and Poria placenta

(26) TABLE-US-00011 MIC (ppm) SI Coriolus Poria Coriolus Poria versicolo placenta versicolor placenta penflufen 0.1 0.1 penflufen:cypermethrin 7:3 0.1 0.1 0.70 0.70 penflufen:cypermethrin 6:4 0.1 0.1 0.60 0.60 penflufen:cypermethrin 1:1 0.1 0.1 0.50 0.50 penflufen:cypermethrin 4:6 0.1 0.1 0.40 0.40 penflufen:cypermethrin 3:7 0.1 0.1 0.30 0.30 penflufen:cypermethrin 2:8 0.3 0.3 0.60 0.60 penflufen:cypermethrin 1:9 0.1 0.5 0.10 0.50 cypermethrin >100 >100

Example 3

Activity Test Analogously to EN113

(27) Penflufen (I) was tested analogously to the EN113 standard test for activity against wood-destroying fungi. In contrast to the standard test, smaller pieces of wood were used and the pieces of wood were exposed to attack by the fungi for a shorter period of time.

(28) To this end, dried test specimen (25154 mm) made of pine (Pinus sylvestris) were in each case vacuum-drenched with solutions of penflufen (I) in toluene. From the concentration of penflufen (I) in the drench solution and the uptake of the drench solution into the test specimen, the amount of active compound taken up by the test specimen (retention) was calculated. The test specimens were dried and then weighed. To prevent falsifying colonisation by foreign pathogens, the test specimen were sterilised with rays.

(29) 3.1 Activity against Poria placenta

(30) The test specimen were brought into contact with the wood-destroying organism Poria placenta and stored for 6 weeks. The test pieces of wood were then cleaned, dried and weighed. This was used to calculate the loss of mass. For each retention, the mean of 6 test specimens was determined.

(31) TABLE-US-00012 No. Retention of penflufen [g/m.sup.3] Loss of mass [%] 1 0 20 2 50 0 3 102 0

(32) Penflufen (I) shows very good activity against the wood-destroying fungus Poria placenta.

(33) 3.2 Activity against Coniophora puteana

(34) The test specimens were brought into contact with the wood-destroying organism Coniophora puteana and stored for 6 weeks. The test pieces of wood were then cleaned, dried and weighed. This was used to calculate the loss of mass. For each retention, the mean of 6 test specimens was determined.

(35) TABLE-US-00013 No. Retention of penflufen [g/m.sup.3] Loss of mass [%] 1 0 24 2 50 0 3 103 0

(36) Penflufen (I) shows very good activity against the wood-destroying fungus Coniophora puteana.