ANHYDROUS COMPOSITION FOR TOPICAL USE THAT IS IN THE FORM OF A DISPERSED PHASE BASED ON AT LEAST ONE SHORT DIOL IN A CONTINUOUS FATTY PHASE

Abstract

Composition for topical use including a gelled phase dispersed in a continuous phase, with: the gelled phase including a diol having 3-8 atoms and represented either by formula (Ia): R.sup.a1-C(R.sup.b1)(OH)—C(OH)(R.sup.c1)(R.sup.d1) (Ia), in which each of the Ra1, Rb1, Rc1 and Rd1 radicals represent, independently of one another, a hydrogen atom or saturated aliphatic radical having 1-5 carbon atoms, or by formula (Ib): R.sup.a1-C(R.sup.b1)(OH)—[C(R.sup.e1)(R.sup.f1)]t-C(OH)(R.sup.c1)(R.sup.d1) (Ib), in which t is equal to one, two or three, each of the R.sup.a1, R.sup.b1, R.sup.c1, R.sup.d1, R.sup.e1 and R.sup.f1 radicals represent, independently of one another, a hydrogen atom or saturated aliphatic radical having 1-5 carbon atoms, it being understood that at least one of the Ra1 or Rb1 radicals and/or at least one of the Rc1 or Rd1 radicals do not represent a hydrogen atom, and —a fatty phase including an oil, an emulsifying surfactant system and an emulsifying surfactant.

Claims

1. A composition (E1) suitable for topical use comprising a gelled phase (A1) free of added water and dispersed in a continuous phase (A2), with: the gelled phase (A1) comprising at least one diol chosen from 1,2-propanediol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 2,3-butanediol, 2,3-pentanediol, 2,3-hexanediol, 2,5-hexanediol or 2-methyl 2,4-pentanediol, and a fatty phase (A2) comprising at least one oil, at least one emulsifying surfactant (S1) and at least one emulsifying surfactant (S2).

2. The composition (E1) as claimed in claim 1, wherein said composition (E1) comprises, per 100% of its weight: from 60% to 98% by weight of the gelled phase (A1), and from 2% to 40% by weight of the fatty phase (A2).

3. The composition (E1) as claimed in claim 1, wherein the emulsifying surfactant (S1) is selected from the elements of the group consisting of alkylpolyglycoside compositions and compositions of alkylpolyglycosides and of fatty alcohols, and the emulsifying surfactant (S2) is selected from the elements of the group consisting of polyglycerol esters, alkoxylated polyglycerol esters, polyglycol polyhydroxystearates, polyglycerol polyhydroxystearates and alkoxylated polyglycerol polyhydroxystearates.

4. The composition (E1) suitable for topical use as claimed in claim 1, wherein the gelled phase (A1) comprises, per 100% of its weight: from 0.5% to 10% by weight of a crosslinked anionic polyelectrolyte (AP1), from 90% to 99.5% by weight of at least one diol chosen from 1,2-propanediol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 2,3-butanediol, 2,3-pentanediol, 2,3-hexanediol, 2,5-hexanediol or 2-methyl 2,4-pentanediol.

5. The composition (E1) suitable for topical use as claimed in claim 4, wherein said diol is chosen from 1,2-propanediol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol or 2-methyl-2,4-pentanediol.

6. The composition (E1) suitable for topical use as claimed in claim 4, wherein the crosslinked anionic polyelectrolyte (AP1) comprises a proportion of greater than or equal to 25 mol % of monomer units derived from 2-methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid in free acid or partially or totally salified form.

7. The composition (E1) suitable for topical use as claimed in claim 1, wherein the emulsifying surfactant (S.sub.1) consists of at least one alkylpolyglycoside composition (C.sub.1) represented by formula (VII):
R.sub.1—O-(G)x-H  (VII) wherein x represents a decimal number between 1.05 and 2.5, G represents the glucosyl or α,β-D-glucopyranosyl radical, obtained from the removal of the hemiacetal hydroxyl group from α,β-D-glucopyranose, and R.sub.1 represents a radical chosen from the elements of the group consisting of the radicals n-dodecyl, n-tetradecyl, n-hexadecyl, n-octadecyl, n-eicosyl and n-behenyl, said composition (C.sub.1) consisting of a mixture of compounds represented by formulae (VII.sub.1), (VII.sub.2), (VII.sub.3), (VII.sub.4) and (VII.sub.5):
R.sub.1—O-(G).sub.1-H  (VII.sub.1)
R.sub.1—O-(G).sub.2-H  (VII.sub.2)
R.sub.1—O-(G).sub.3-H  (VII.sub.3)
R.sub.1—O-(G).sub.4-H  (VII.sub.4)
R.sub.1—O-(G).sub.5-H  (VII.sub.5), in the respective molar proportions a.sub.1, a.sub.2, a.sub.3, a.sub.4 and a.sub.5 such that: the sum a.sub.1+a.sub.2+a.sub.3+a.sub.4+a.sub.5 is equal to 1 and that the sum a.sub.1+2a.sub.2+3a.sub.3+4a.sub.4+5a.sub.5 is equal to x.

8. The composition (E1) suitable for topical use as claimed in claim 1, wherein the emulsifying surfactant (S.sub.1) consists of at least one composition (C.sub.2) comprising, per 100% of its weight: from 10% to 50% by weight of at least one alkylpolyglycoside composition (C.sub.1) represented by formula (VII):
R.sub.1—O-(G)x-H  (VII), wherein x represents a decimal number between 1.05 and 2.5, G represents the glucosyl or α,β-D-glucopyranosyl radical, obtained from the removal of the hemiacetal hydroxyl group from α,β-D-glucopyranose, and R.sub.1 represents a radical chosen from the elements of the group consisting of the radicals n-dodecyl, n-tetradecyl, n-hexadecyl, n-octadecyl, n-eicosyl and n-behenyl, said composition consisting of a mixture of compounds represented by formulae (VII.sub.1), (VII.sub.2), (VII.sub.3), (VII.sub.4) and (VII.sub.5):
R1-O-(G)1-H  (VII1)
R1-O-(G)2-H  (VII2)
R1-O-(G)3-H  (VII3)
R1-O-(G)4-H  (VII4)
R1-O-(G)5-H  (VII5) in the respective molar proportions a.sub.1, a.sub.2, a.sub.3, a.sub.4 and a.sub.5 such that: the sum a.sub.1+a.sub.2+a.sub.3+a.sub.4+a.sub.5 is equal to 1 and that the sum a.sub.1+2a.sub.2+3a.sub.3+4a.sub.4+5a.sub.5 is equal to x; and from 90% to 50% by weight of at least one fatty alcohol of formula (VIII):
R″.sub.1—OH  (VIII), wherein R″.sub.1 represents a radical chosen from the elements of the group consisting of the radicals n-dodecyl, n-tetradecyl, n-hexadecyl, n-octadecyl, n-eicosyl and n-behenyl, where R″.sub.1 may be identical to or different from R.sub.1.

9. The composition (E1) suitable for topical use as defined in claim 1, wherein the emulsifying surfactant (S.sub.1) consists of at least one alkylpolyglycoside composition (C′.sub.1) represented by formula (IX):
R.sub.1—O-(G).sub.x-H  (IX) wherein x represents a decimal number between 1.05 and 2.5, G represents the xylose residue and R.sub.1 represents the 2-octyldodecyl radical, said composition (C′.sub.1) consisting of a mixture of compounds represented by the formulae (IX.sub.1), (IX.sub.2), (IX.sub.3), (IX.sub.4) and (IX.sub.5):
R.sub.1—O-(G).sub.1-H  (IX.sub.1)
R.sub.1—O-(G).sub.2-H  (IX.sub.2)
R.sub.1—O-(G).sub.3-H  (IX.sub.3)
R.sub.1—O-(G).sub.4-H  (IX.sub.4)
R.sub.1—O-(G).sub.5-H  (IX.sub.5) in the respective molar proportions a.sub.1, a.sub.2, a.sub.3, a.sub.4 and a.sub.5 such that: the sum a.sub.1+a.sub.2+a.sub.3+a.sub.4+a.sub.5 is equal to 1 and that the sum a.sub.1+2a.sub.2+3a.sub.3+4a.sub.4+5a.sub.5 is equal to x.

10. The composition (E1) suitable for topical use as defined in claim 1, wherein said emulsifying system (S.sub.1) consists of a composition (C′.sub.2) comprising, per 100% of its weight: from 10% to 50% by weight of at least one alkylpolyglycoside composition (C′1) represented by formula (X):
R.sub.1—O-(G).sub.x-H  (X) wherein x represents a decimal number between 1.05 and 2.5, G represents the xylose residue and R.sub.1 represents the 2-octyldodecyl radical, said composition consisting of a mixture of compounds represented by formulae (X.sub.1), (X.sub.2), (X.sub.3), (X.sub.4) and (X.sub.5):
R.sub.1—O-(G).sub.1-H  (X.sub.1)
R.sub.1—O-(G).sub.2-H  (X.sub.2)
R.sub.1—O-(G).sub.3-H  (X.sub.3)
R.sub.1—O-(G).sub.4-H  (X.sub.4)
R.sub.1—O-(G).sub.5-H  (X.sub.5) in the respective molar proportions a.sub.1, a.sub.2, a.sub.3, a.sub.4 and a.sub.5 such that: the sum a.sub.1+a.sub.2+a.sub.3+a.sub.4+a.sub.5 is equal to 1 and that the sum a.sub.1+2a.sub.2+3a.sub.3+4a.sub.4+5a.sub.5 is equal to x; and from 90% to 50% by weight of at least one fatty alcohol of formula (XI):
R′″.sub.1—OH  (XI), wherein R′″.sub.1 represents the 2-octyldodecyl radical.

11. The composition (E1) suitable for topical use as claimed in claim 1, wherein the emulsifying surfactant (S.sub.2) consists of at least one polyglycol polyhydroxystearate represented by the formula (XII): ##STR00008## wherein y2 represents an integer greater than or equal to 2 and less than or equal to 50, R.sub.4 represents a hydrogen atom, a methyl radical or an ethyl radical, and Z.sub.2 represents a radical of formula (XIII): ##STR00009## wherein y′.sub.2 represents an integer greater than or equal to 0 and less than or equal to 10, and Z′.sub.2 represents a radical of formula (XIII) as defined above, where Z′.sub.2 may be identical to or different from Z.sub.2, or a hydrogen atom.

12. The composition (E1) suitable for topical use as claimed in claim 1, further comprising one or more auxiliary compounds chosen from foaming and/or detergent surfactants, thickening and/or gelling surfactants, thickening and/or gelling agents, stabilizers, film-forming compounds, solvents and cosolvents, hydrotropic agents, plasticizers, emulsifiers and co-emulsifiers, opacifiers, self-tanning agents, nacreous agents, superfatting agents, sequestrants, chelating agents, antioxidants, fragrances, essential oils, preserving agents, conditioning agents, deodorants, bleaching agents intended for bleaching bodily hair and the skin, active ingredients intended to provide a treating and/or protective action to the skin or the hair, sunscreens, mineral fillers or pigments, particles that give a visual effect or that are intended for encapsulating active agents, exfoliant particles, texturing agents, optical brighteners and insect repellents.

13. The composition (E.sub.1) suitable for topical use as claimed in claim 12, further comprising, per 100% of its weight, a proportion of between 0.5% by weight and 10% by weight of one or more self-tanning agents.

14. A method for the cosmetic treatment of the skin, the hair, the scalp and/or the lips, comprising applying an effective amount of the composition of claim 1.

15. A method for cleaning, protecting or caring for the skin, the hair, the scalp or the lips, comprising applying an effective amount of the composition of claim 1.

16. A method for artificially tanning and/or browning human skin, comprising applying an effective amount of the composition of claim 1.

17. A cosmetic treatment process for artificially tanning and/or browning human skin, comprising at least one step of applying to said human skin the composition as defined in claim 13.

18. The composition (E1) as claim 2, wherein the emulsifying surfactant (S1) is selected from the elements of the group consisting of alkylpolyglycoside compositions and compositions of alkylpolyglycosides and of fatty alcohols, and the emulsifying surfactant (S2) is selected from the elements of the group consisting of polyglycerol esters, alkoxylated polyglycerol esters, polyglycol polyhydroxystearates, polyglycerol polyhydroxystearates and alkoxylated polyglycerol polyhydroxystearates.

19. The composition (E1) suitable for topical use as claimed in claim 2, wherein the gelled phase (A1) comprises, per 100% of its weight: from 0.5% to 10% by weight of a crosslinked anionic polyelectrolyte (AP1), from 90% to 99.5% by weight of at least one diol chosen from 1,2-propanediol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 2,3-butanediol, 2,3-pentanediol, 2,3-hexanediol, 2,5-hexanediol or 2-methyl 2,4-pentanediol.

20. The composition (E1) suitable for topical use as claimed in claim 3, wherein the gelled phase (A1) comprises, per 100% of its weight: from 0.5% to 10% by weight of a crosslinked anionic polyelectrolyte (AP1), from 90% to 99.5% by weight of at least one diol chosen from 1,2-propanediol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 2,3-butanediol, 2,3-pentanediol, 2,3-hexanediol, 2,5-hexanediol or 2-methyl 2,4-pentanediol.

Description

DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0070] The examples that follow illustrate the invention without, however, limiting it.

Preparation and Evaluation of Emulsions According to the Invention and of Comparative Emulsions

1) Preparation of the Emulsions According to the Invention and of the Comparative Emulsions

[0071] Three emulsions according to the invention, denoted (F.sub.1) to (F.sub.3), and four comparative emulsions, denoted (F′.sub.1) to (F′.sub.4), the proportions by weight of the constituents of which are recorded in table 1 below, the contents by weight of the polyelectrolytes being indicated as a percentage of polymeric solids, are prepared by performing the following process.
The constituents of the fatty phase are introduced successively into a beaker, mixed and brought to a temperature of 20° C. after an 80° C. heating step; the mixing is performed using a mechanical stirrer equipped with a propeller-type stirring spindle at a speed of 100 rpm.
The constituents of the dispersed phase are mixed at ambient temperature in a beaker using a mechanical stirrer at a speed of 2000 rpm and the thickener is then added gradually. The stirring is maintained for a duration which makes it possible to obtain a phase which is in the form of a homogeneous gel. The fatty phase is added in one go to the gel at ambient temperature and at a moderate stirring speed (75 to 300 rpm) using a stirrer equipped with an anchor-type spindle. This stirring is then maintained for 10 minutes and no cooling step is necessary.

TABLE-US-00001 TABLE 1 (F.sub.1) (F.sub.2) (F.sub.3) (F′.sub.1) (F′.sub.2) (F′.sub.3) (F′.sub.4) Continuous fatty phase Lanol ™ 2681 .sup.(1) 5% 5% 5% 5% 5% 5% 5% Sepineo ™ SE 68.sup.(2) 0.4%.sup.  0% 0% 0% 0% 0% 0% Sepicide ™ HB .sup.(3) 1% 1% 1% 1% 1% 1% 1% Simaline ™WO.sup.(4) 1.1%.sup.  1.1%.sup.  1.1%.sup.  1.1%.sup.  1.1%.sup.  1.1%.sup.  1.1%.sup.  Montane ™80.sup.(6) 0% 0% 0% 1.2%.sup.  1.2%.sup.  1.2%.sup.  1.2%.sup.  Montanov ™202.sup.(8) 0% 0.4%.sup.  0% 0% 0% 0% 0% Fluidanov ™20X.sup.(9) 0% 0% 0.4%.sup.  0% 0% 0% 0% Dispersed phase Sepineo ™P600.sup.(5) 2% 2% 2% 2% 2% 2% 2% PEG-400.sup.(7) 0% 0% 0% 0% 0% 0% 50%  Glycerol 0% 0% 0% 0% 0% 60%  0% Water 0% 0% 0% 0% 10.5%.sup.(*.sup.)  30.5%.sup.(*.sup.)  40.5%.sup.(*.sup.)  1,2-propanediol 90.5%   90.5%   90.5%   90.5%   80%  0% 0% .sup.(1) Lanol ™ 2681, or Coco-Caprylate/Caprate. .sup.(2)Sepineo ™ SE 68 is a mixture comprising, per 100% of its weight, from 78% to 85% by weight of a mixture of n-hexadecanol and n-octadecanol, and from 15% to 22% by weight of a mixture of n-hexadecyl glucoside with a mean degree of polymerization of 1.20 and n-octadecyl glucoside with a mean degree of polymerization of 1.20, used as emulsifying agent. .sup.(3) Sepicide ™ HB is a mixture of phenoxyethanol, methylparaben, ethylparaben, butylparaben and n-propylparaben, used as a preserving agent. .sup.(4)Simaline ™ WO, or PEG 30 Dipolyhydroxystearate, is an emulsifying surfactant. .sup.(5)Sepineo ™ P600 is a self-invertible inverse latex comprising, per 100% of its weight, between 30% and 40% by weight of a crosslinked copolymer of acrylamide and of sodium acryloyldimethyltaurate, used as a thickening agent. .sup.(6)Montane ™ 80 is a composition comprising sorbitan monooleate, used as water-in-oil type emulsifying agent. .sup.(7)PEG-400 is a polyethylene glycol with a molecular weight of approximately 400 g .Math. mol.sup.−1. .sup.(8)Montanov ™ 202 is a mixture comprising, per 100% of its weight, from 80% to 90% by weight of a mixture of arachidyl alcohol and behenyl alcohol, and from 10% to 20% by weight of arachidyl polyglucosides with an average degree of polymerization of 1.20, used as an emulsifying agent. .sup.(9)Fluidanov ™ 20X is a mixture comprising, per 100% of its weight, from 70% to 90% by weight of 2-octyl-1-dodecanol and from 10% to 30% by weight of 2-octyl-1-dodecanyl polyxyloside. .sup.(*.sup.)minimum weight proportion of water that could be added to the respective comparative emulsions (F.sub.2), (F′.sub.3), (F′.sub.4) without either obtaining gelation preventing stirring of said emulsion, or obtaining an emulsion exhibiting a heterogeneous appearance that persists despite the stirring phases of the preparation process, or a form for which the dispersed phase is the fatty phase.
2 Demonstration of the Properties of Emulsions (F.sub.1) to (F.sub.3) According to the Invention and of Comparative Emulsions (F′.sub.1) to (F′.sub.4)
2.1 Characterization of the Appearance and Viscosity of Emulsions (F.sub.1) to (F.sub.3) According to the Invention and of Comparative Emulsions (F′.sub.1) to (F′.sub.4)
The emulsions (F.sub.1) to (F.sub.3) and (F′.sub.1) to (F′.sub.4) obtained according to the process described above are then stored in an insulated climatic chamber regulated at a temperature of 25° C. for 3 months. After the conclusion of this period of three months, the appearance (APP) of each emulsion prepared is observed and the dynamic viscosity (μ) of each emulsion is measured (in mPas) by means of a viscometer at 25° C. (Brookfield LVT, speed 6).
An aliquot of these same emulsions (F.sub.1) to (F.sub.3) and (F′.sub.1) to (F′.sub.4) obtained according to the process described above is also stored in an insulated climatic chamber regulated at a temperature of 45° C. for three months. After the conclusion of this period of three months, the appearance (APP) of each emulsion prepared is observed and the dynamic viscosity (μ) of each emulsion is measured (in mPas) by means of a viscometer at 25° C. (Brookfield LVT, speed 6).
2.2 Characterization of the Direction of the Emulsions (F.sub.1) to (F.sub.3) According to the Invention and of the Comparative Emulsions (F′.sub.1) to (F′.sub.3)
The conductivity (σ) of the emulsions (F.sub.1) to (F.sub.3) according to the invention and of the emulsions (F′.sub.1) to (F′.sub.3) is measured at 25° C., after a period of storage of said emulsions of one day in an insulated climatic chamber regulated at a temperature of 25° C., by means of an LF 196™ brand conductivity meter from the company WTW equipped with a TetraCon™ 96 electrode. For a given emulsion, (σ)≤0.5 μS.Math.cm.sup.−1, the emulsion is considered to be non-conductive and consequently the external phase is not the phase based on 1,2-propanediol or on glycerol or on PEG-400, but the oily phase.
Indeed, the conductivity, measured at 25° C., of 1,2-propanediol is equal to 4400 μS.Math.cm.sup.−1, that of glycerol is 6400 μS.Math.cm.sup.−1.
For a given emulsion, (σ)>0.5 μS.Math.cm.sup.−1, the emulsion is considered to be conductive and consequently the external phase is considered not to be the oily phase but the glycolic phase. The term “glycolic phase” means the phase based on 1,2-propanediol or on glycerol or on PEG-400.
This same measurement of the conductivity of the emulsions (F.sub.1) to (F.sub.3) according to the invention and of the comparative emulsions (F′.sub.1) to (F′.sub.3) is measured at 25° C. after three months at 25° C., and after three months at 45° C.
2.3 Results Obtained for the Emulsions (F.sub.1) to (F.sub.3) According to the Invention and for the Comparative Emulsions (F′.sub.1) to (F′.sub.3)
The evaluation methods described in sections 2.1 and 2.2 were applied to the emulsions (F.sub.1) to (F.sub.3) according to the invention and to the comparative emulsions (F′.sub.1) to (F′.sub.3). The results obtained are recorded in table 2 below.

TABLE-US-00002 TABLE 2 (F1) (F2) (F3) (F′1) (F′2) (F′3) (F′4) (APP) Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous at 1 day liquid liquid liquid liquid liquid liquid liquid (visual) (σ) at 1 ≤0.5 ≤0.5 ≤0.5 >0.5 ≤0.5 ≤0.5 ≤0.5 day at μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 25° C. Dispersed Glycolic Glycolic Glycolic Fatty Glycolic Glycolic Glycolic phase phase phase phase phase phase phase phase (APP) at Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous 7 days liquid liquid liquid liquid liquid liquid liquid at 25° C. (σ) at ≤0.5 ≤0.5 ≤0.5 >0.5 ≤0.5 ≤0.5 ≤0.5 3 months μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 at 25° C. (μ) at 43 000 44 200 48 000 not not not not 3 months mPas mPas mPas measured measured measured measured at 25° C. (APP) at Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous 3 months liquid liquid liquid liquid liquid liquid liquid at 45° C. (σ) at ≤0.5 ≤0.5 ≤0.5 >0.5 ≤0.5 ≤0.5 ≤0.5 3 months μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 μS .Math. cm.sup.−1 at 45° C.

2.4 Analysis of the Results

[0072] The emulsions (F.sub.1) to (F.sub.3) according to the invention are therefore characterized by: [0073] a stability of their form, of the type based on 1,2-propanediol dispersed in oil, after storage for 3 months at a temperature of 25° C.; the appearance observed after this storage period is still homogeneous; [0074] a stability of their form, of the type based on 1,2-propanediol dispersed in oil, after storage for 3 months at a temperature of 45° C.; the appearance observed after this storage period is still homogeneous;
The comparative emulsion (F′.sub.1) comprising sorbitan monooleate as oil-in-water lipophilic surfactant does not make it possible to obtain an emulsion wherein the dispersed phase is the phase based on 1,2-propanediol.
The comparative emulsions (F′.sub.2), (F′.sub.3) and (F′.sub.4), also comprising sorbitan monooleate as oil-in-water lipophilic surfactant, make it possible to obtain an emulsion wherein the dispersed phase is the phase based on 1,2-propanediol, but a minimum amount of water is necessary. Unexpectedly, the use of the water-in-oil emulsifying surfactant, sorbitan monooleate, does not make it possible to obtain an emulsion wherein the dispersed phase is the phase based on 1,2-propanediol without the addition of water (F′2 compared to F′1); the same is true with the use of other polyols commonly used to prepare formulations for topical application (F′3 and F′4).