Cosmetic Cream with Anti-Oxidant Activity

Abstract

The proposed cosmetic cream formula contains predetermined quantities of the following ingredients: Grapeseed oil, Spirulina extract, Taxifolin/Dihydroquercetin, Beta-Cyclodextrine, Cetearyl Alcohol, Cetearyl Glucoside, 1,2 Propylene Glycol, Phenylethyl Alcohol, Benzyl Alcohol, Sorbin Acids and Distilled water. The presence of Spirulina extract and Taxifolin in water soluble form in the oil-water base formula of the proposed cosmetic cream provides for a synergetic effect that greatly enhances Spirulina's skin protection properties. There is also disclosed a preferable content of ingredients for preparation of the Spirulina extract.

Claims

1. A cosmetic cream, comprising (in weight % for 1 kg): Grapeseed oil (Vitis Vinifera Oil): 0.10-0.90; Spirulina extract: 0.001-0.01; Taxifolin/Dihydroquercetin: 0.001-0.1; Beta-Cyclodextrine: 0.001-0.1; Cetearyl Alcohol, Cetearyl Glucoside, 1,2 Propylene Glycol, Phenylethyl Alcohol, Benzyl Alcohol, Sorbin Acids: variable from 0.001 to 1; and Distilled water: 0.20-0.90.

2. The cosmetic cream in claim 1, wherein the Spirulina extract has the following dry content (nutritional value per 100 g/3.5 oz): Carbohydrates 23.9 g; Sugars 3.1 g; Dietary fiber 3.6 g; Fat 7.72 g; Saturated fat 2.65 g; Monounsaturated fat 0.675 g; Polyunsaturated 2.08 g; Protein 57.47 g; Tryptophan 0.929 g; Threonine 2.97 g; Isoleucine 3.209 g; Leucine 4.947 g; Lysine 3.025 g; Methionine 1.149 g; Cystine 0.662 g; Phenylalanine 2.777 g; Tyrosine 2.584 g; Valine 3.512 g; Valin 3.512; Arginine 4.147 g; Histidine 1.085 g; Alanine 4.515 g; Aspartic acid 5.793 g; Glutamic acid 8.386 g; Glycine 3.099 g; Proline 2.382 g; Serine 2.998 g; TABLE-US-00003 Vitamins: Vitamin A equiv 29 g; beta-carotene 342 g; Thiamine (B1) 2.38 mg; Riboflavin (B2) 3.67 mg; Niacin (B3) 12.82 mg; Pantothenic acid (B5) 3.48 mg; Vitamin B6 0.364 mg; Folate (B9) 94 g; Choline 66 mg; Vitamin C 10.1 mg; Vitamin E 5 mg; Vitamin K 25.5 g; and Minerals: Calcium 120 mg; Iron 28.5 mg; Magnesium 195 mg; Manganese 1.9 mg; Phosphorus 118 mg; Potassium 1363 mg; Sodium 1048 mg; and Zinc 2 mg.

Description

DRAWINGS OF THE INVENTION

[0029] The present invention is illustrated in the attached drawings.

[0030] FIG. 1 shows a chemical structure of Taxifolin (Dihydroquercetin) and its analogues wherein:

R1R3R4R6R7OH, R2R5H; R2H, R1R3R4R6R7OH, according to an embodiment of the invention.

[0031] FIG. 2 shows a chemical structure of Quercetin and its analogues wherein:

R1R3R4R6R7OH, R2R5H; R2H, R1R3R4R6R7OH, according to another embodiment of the invention.

[0032] FIG. 3 shows a chemical structure wherein: R2R5H, R1R3R6R7OH, R4O-diglucoside, according to another embodiment of the invention.

DETAIL DESCRIPTION OF THE INVENTION

[0033] While the invention may be susceptible to embodiment in different forms, there are shown in the drawings, and will be described in detail herein, specific embodiments of the present invention, with the understanding that the present disclosure is to be considered an exemplification of the principles of the invention, and is not intended to limit the invention to that as illustrated and described herein.

[0034] The above stated object has been achieved in the present invention by using an oil-in-water technique formulation.

[0035] Except Taxifolin, the structures shown in FIGS. 1-3 can be used as an antioxidant in the inventive formula. Solubility of flavonoids in water is achieved with a formation inclusive complex with -Cyclodextrin at a temperature of 40-45 C.

[0036] Spirulina platensis (SP), a blue-green algae (photosynthesizing cyanobacterium) having diverse biological activity is biopolymer cyanobacterium that is also used in the inventive cream formula.

[0037] Due to a high content of highly valuable proteins, indispensable amino acids, vitamins, beta-carotene and other pigments, mineral substances, indispensable fatty acids and polysaccharides, SP has been found suitable for use as bioactive additive. SP produces an immune stimulating effect by enhancing the resistance of mammals and fish to infections and has the capacity to influence hemopoiesis, stimulating the production of antibodies and cytokines.

[0038] Under the influence of SP macrophages, T and B cells are activated. SP sulfolipids have proved to be effective against HIV. Preparations obtained from SP biomass have also been found active against herpes virus, cytomegalovirus, influenza virus, etc. SP extracts are capable in inhibiting cancerogenesis.

[0039] SP preparations are regarded as functional products contributing to the preservation of the resident intestinal microflora, especially lactic acid bacilli and bifidobacteria, and to a decrease in the level of Candida albicans. The biological activity of SP with respect to microorganisms holds good promise in using these microalgae as components of culture media.

[0040] Although Spirulina contains a lot of useful ingredients that are usually used in cosmetic formulas in separate forms, Spirulina was never used in cosmetic formulas with water soluble bioflavonoids like antioxidants. However, the authors have established that flavonoid antioxidant present in a water-soluble form with enhanced bioavailability helps greatly increase Spirulina's skin protection properties.

[0041] Spirulina extract used for the inventive formulation of cream has the following dry weight content (nutritional value per 100 g/3.5 oz):

Carbohydrates 23.9 g; Sugars 3.1 g; Dietary fiber 3.6 g; Fat 7.72 g; Saturated fat 2.65 g; Monounsaturated fat 0.675 g; Polyunsaturated 2.08 g; Protein 57.47 g; Tryptophan 0.929 g; Threonine 2.97 g; Isoleucine 3.209 g; Leucine 4.947 g; Lysine 3.025 g; Methionine 1.149 g; Cystine 0.662 g; Phenylalanine 2.777 g; Tyrosine 2.584 g; Valine 3.512 g; Valin 3.512; Arginine 4.147 g; Histidine 1.085 g; Alanine 4.515 g; Aspartic acid 5.793 g; Glutamic acid 8.386 g; Glycine 3.099 g; Proline 2.382 g; Serine 2.998 g;

TABLE-US-00001 Vitamins: Vitamin A equiv 29 g; beta-carotene 342 g; Thiamine (B1) 2.38 mg; Riboflavin (B2) 3.67 mg; Niacin (B3) 12.82 mg; Pantothenic acid (B5) 3.48 mg; Vitamin B6 0.364 mg; Folate (B9) 94 g; Choline 66 mg; Vitamin C 10.1 mg; Vitamin E 5 mg; Vitamin K 25.5 g; Minerals: Calcium 120 mg; Iron 28.5 mg; Magnesium 195 mg; Manganese 1.9 mg; Phosphorus 118 mg; Potassium 1363 mg; Sodium 1048 mg; and Zinc 2 mg.

[0042] Energy value of 100 g of the formulation is 1.213 kJ (290 kcal)

[0043] The inventive formula also includes Grapeseed oil (Vitis Vinifera Oil) as a basic ingredient. Grapeseed oil is often used as a cosmetic ingredient for damaged or stressed tissues because it has regenerative qualities, specifically for collagen regeneration and capillary support. It is especially effective for repair of the skin around the eyes, and in the repair of stretch marks.

[0044] Grapeseed oil contains a high amount of linoleic acid, nourishing to skin anti-inflammatory, antiseptic and mildly astringent. Grapeseed oil also contains antioxidant polyphenol, which, in a mixture with Taxifolin, synergistically enhances their mutual antioxidant activity, which further contributes into the resultant synergistic effect of the inventive formula. Grapeseed oil is rich in linoleic acid, oleic acid, palmitic acid, stearic acid and palmit oleic acid. Additionally, Grapeseed oil contains vitamin E, C, D and Beta-carotene.

[0045] These qualities make Grapeseed oil especially valuable for antiaging skin care. However, since Grapeseed oil is a light oil, it is suitable for all skin types, including oily skin.

[0046] The inventive formula also includes usual cosmetic ingredients used for stability of cosmetic products: Cetearyl Alcohol, Cetearyl Gluco side 1.2, Propylene Glycol, Phenylethyl Alcohol, Benzyl Alcohol, and Sorbin Acids.

[0047] The TABLE below lists the preferable content of all ingredients of the cream formula in weight % for 1 kg of the inventive cosmetic cream:

TABLE-US-00002 1 Distilled water 0.20-0.90 2 Grape seeds oil (Vitis 0.10-0.90 Vinifera Oil) 3 Spirulina extract 0.001-0.01 4 Taxifolin/ 0.001-0.10 Dihydroquercetin 5 Beta-Cyclodextrine 0.001-0.10 8 Cetearyl Alcohol, Cetearyl 0.01-1 Glucoside,1,2 Propylene Glycol, Phenylethyl Alcohol, Benzyl Alcohol, Sorbin Acids