Live attenuated infectious laryngotracheitis virus (ILTV) vaccines and preparation thereof

Abstract

This disclosure describes a modified live infectious laryngotracheitis virus (ILTV) developed from a strain of ILTV grown at a reduced incubation temperature, vaccines that include the modified live ILTV, methods for producing the live modified ILTV, and methods that include administering the modified ILTV to a subject.

Claims

1. A method of producing a live attenuated infectious laryngotracheitis virus (ILTV), the method comprising serially passaging the ILTV in culture for at least 15 serial passages at a temperature of at least 25 C. and no greater than 35 C.

2. The method of claim 1 wherein ILTV is passaged for at least 30 serial passages.

3. The method of claim 1 wherein the ILTV is passaged in culture at a temperature of from 28 C. to 31 C.

4. The method of claim 2 wherein the ILTV is passaged in culture at a temperature of from 28 C. to 31 C.

Description

BRIEF DESCRIPTION OF THE FIGURES

(1) FIG. 1. ILTV lesions, also referred to as plaques or pocks, on the chorioallantoic membrane (CAM) of the embryonating chicken egg at five days following inoculation. (A) Appearance of unique ILTV lesions on the CAM following inoculation with clone 5-7. Note the small well defined plaques. (B) Appearance of a typical ILTV plaque on the CAM. Note diffuse spreading lesion following inoculation with experimental vaccine P32 37C.

DETAILED DESCRIPTION OF ILLUSTRATIVE EMBODIMENTS

(2) The disclosure relates to live attenuated infectious laryngotracheitis viruses (ILTVs) and the use of the live attenuated ILTVs as vaccines for poultry. Poultry such as, for example, broiler chickens, vaccinated with the vaccine may have a lower incidence of clinical disease signs and/or increased growth (as measured, for example, by greater weight gain), than poultry vaccinated with chick embryo origin (CEO) vaccines. Also, poultry vaccinated using the methods and vaccines described herein can have improved weight gain compared an unvaccinated poultry after being challenged with a virulent challenge strain of ILTV.

(3) Modified live vaccines of two types have been available for many years to control infectious laryngotracheitis (ILT): vaccines of chick embryo origin (CEO) and vaccines of tissue culture origin (TCO). The CEO products often exhibit negative side effects such as, for example, causing disease, reducing growth rates (exhibited as reduce weight gain), and reducing feed efficiency. Because of the side effect produced by the CEO vaccines, poultry producers may prefer not to use them unless it becomes absolutely necessary to do so. Thus, many flocks go unvaccinated and are susceptible to the disease.

(4) There are limited options for commercially available TCO vaccines. A TCO product is typically milder than a CEO vaccine, but is typically administered via the ocular route. This severely limits its practical commercial use by poultry producers because the vaccine must be instilled into the conjunctiva of each individual bird of a flock. This eye drop application can be laborious and expensive. Thus, poultry producers disfavor the process and, consequently, TCO vaccines.

(5) More recently, a third type of vaccine, a recombinant ILTV vaccine, has been commercialized. A recombinant ILTV product can express one or more immunogenic proteins, but not the complete virus, and thus fail to produce side effects associated with CEO vaccines. A disadvantage of recombinant vaccines, however, is that they can be expensive to purchase compared to live vaccines, and are only partially effective. If a safer and effective live vaccine could be developed, the cost of vaccine production would dramatically reduce costs to control ILT.

(6) The new vaccine described herein can replace the use of existing modified live and recombinant vaccines. For example, in commercial use with broiler chicken production, a vaccine prepared with the live attenuated ILTV described herein can offer a cheaper alternative to recombinant vaccines and be safer than current modified live vaccines. As another example, in commercial production of breeder chickens and/or layer chickens, the live attenuated ILTV described herein can be a component of a primary vaccine could be used for primary vaccination, which can be followed with one or more booster vaccinations using, for example, currently available CEO vaccines.

(7) In one embodiment, a commercially available vaccine referred to as a tissue culture origin (TCO) vaccine (LT-IVAX, Merck Animal Health, Summit, N.J.), was serially passaged up to approximately 40 times in successive cultures of chicken kidney cells (CKC) in cell culture maintained at 30 C., an incubation temperature lower than the typical culture temperature used to grow ILTV (37 C.). The virus was then cloned in CKC culture at 30 C. by limiting dilution to obtain a more homogeneous virus population than is typically produced without limiting dilution. The more homogeneous virus population can produce more consistent vaccine characteristics when administered to poultry.

(8) Most poultry vaccines are grown at 37 C. As just discussed above, the ILTV described herein (P32 30C) was produced serially passaging the virus in culture at a temperature of 30 C. A corresponding ILTV (P32 37C) was prepared similarly to the P32 30C ILTV except that it was generated by serially passaging the virus in a culture maintained at 37 C. The resulting experimental vaccines were tested in chickens and found to be safe and efficacious by the ocular/eye drop and oral routes of administration.

(9) TABLE-US-00001 TABLE 1 Post-vaccination assessment of ILTV commercial and experimental vaccines in two-week-old broiler chickens vaccinated by the ocular or oral routes. Weight Gain From 1-6 Days Post Vaccination Clinical Disease As a % of Non-Vacc. Signs Associated Group Treatment Weight Gain With Vaccination Combined Bodyweight & Clinical Disease Signs Data Following Ocular or Oral Vaccination 1 TCO.sup.A Commercial 94 6/15 2 CEO.sup.B Commercial 92 12/15 3 P32 37 C..sup.C 87 4/15 4 P32 30 C..sup.D 92 1/15 5 No Vaccine 100 0/15 Bodyweight & Clinical Disease Signs Data Post Ocular Vaccination 1 TCO Commercial 89 2/5 2 CEO Commercial 93 5/5 3 P32 37 C. 105 1/5 4 P32 30 C. 103 0/5 5 No Vaccine 100 0/5 Bodyweight & Clinical Disease Signs Data Post Oral Vaccination 1 TCO Commercial 96 4/10 2 CEO Commercial 92 7/10 3 P32 37 C. 78 3/10 4 P32 30 C. 87 1/10 5 No Vaccine 100 0/10 .sup.ATCO = Tissue culture origin (LT-IVAX, Merck Animal Health, Summit, NJ). .sup.BCEO = Chicken embryo origin (TRACHIVAX, Merck Animal Health, Summit, NJ). .sup.CP32 37 C. = 32 tissue culture passages performed at 37 C. .sup.DP32 30 C. = 32 tissue culture passages performed at 30 C.

(10) Vaccination with commercial (TCO Commercial and CEO Commercial) and experimental (P32 37C and P32 30C) vaccines exhibited somewhat reduced growth of broiler chickens as measured by bodyweight gain (Table 1). The negative effect of vaccination on bodyweight gain is a general drawback to the use of modified live vaccines for controlling ILTV infections. The negative effect on bodyweight gain is typically offset by improved health of vaccinated birds compared to non-vaccinated birds beyond the period reflected in Table 1.

(11) Another disadvantage to using modified live vaccines is their tendency to produce clinical disease signs following vaccination. The P32 30C vaccine produced the fewest number of chickens with clinical disease signs. Clinical disease signs include, for example, conjunctival swelling and/or reddening, presence of an ocular and/or nasal (nares) exudate, nasal sinus swelling, labored breathing, and/or coughing, and in severe cases, a bloody expectoration.

(12) TABLE-US-00002 TABLE 2 Post-vaccination assessment of ILTV commercial and experimental vaccines in two-week-old broiler chickens vaccinated by the ocular or oral routes. Q-PCR and ILT Serum Antibody Data Following Ocular or Oral Vaccination ILTV Serology-Day 14 Q-PCR Values-Day 6 Post Vaccination Post Vaccination ILTV #of Chickens Total Group Antibody with Positive Group Treatment Combined Ocular Oral Titers Titer/Total 1 TCO Commercial 31.6 35.2 29.8 184 3/15 2 CEO Commercial 29.0 27.3 29.9 1003 12/15 3 P32 37C 33.2 34.1 35.9 1301 12/15 4 P32 30C 36.5 39.4 35.1 15 6/15 5 No Vaccine 46.0 46.0 46.0 0 0/15

(13) Quantitative (Q)-PCR values are an indication of the presence of ILTV vaccine in the oral/pharyngeal cavity, a body site where the vaccine may be detected. Values are inversely related to virus levels; Lower Q-PCR values equate to the presence of higher virus genome levels. Regardless of the type of vaccine tested, ILTV was not detected in great quantities on Day 6 post-vaccination.

(14) The findings indicate that chickens given the CEO Commercial vaccine had the highest levels of ILTV-specific genome based on Q-PCR. A difference of 3.0 between Q-PCR values represents a 10-fold difference in the level of detectable viral genome. Chickens vaccinated with the P32 30C vaccine showed the lowest level of ILTV in the oral/pharyngeal cavity, suggesting that the vaccine is more attenuated than the other vaccines tested.

(15) Serum antibody titers for ILTV were measured on day 14 post-vaccination using a commercial ELISA kit (Synbiotics Corp., Kansas City, Mo.). The CEO Commercial and P32 37C vaccines induced the highest antibody titers, detected in 12/15 chickens. This finding, along with the higher incidence of clinical disease signs and weight suppression suggest that the CEO Commercial and P32 37C experimental vaccines were not attenuatedi.e., they were more invasive than the TCO Commercial and P32 30C vaccines. Moreover, ELISA serum antibody titers may not correlate well with protection (Fahey et al. 1990. J. Gen. Virol. 71:2401-2405). Thus, a more attenuated vaccine like the P32 30C vaccine can induce protection (Table 3) even when producing low serum antibody titers.

(16) TABLE-US-00003 TABLE 3 Post-challenge assessment of ILTV commercial and experimental vaccines in two-week-old broiler chickens vaccinated by the ocular or oral routes. Weight Gain From 1-6 Birds with Days Post Challenge Clinical Disease Microscopic As a % of Non-Vacc. Signs Associated Pathology Group Treatment Weight Gain With ILTV Infection Eyelid Trachea Bodyweight and Protection (Clinical Signs and Microscopic Pathology) Data After Challenge of Chickens Vaccinated via the Ocular or Oral Routes-Combined Data 1 TCO Commercial 678 0/13 0/13 0/13 2 CEO Commercial 711 0/13 0/13 0/13 3 P32 37 C. 677 0/13 0/13 0/13 4 P32 30 C. 741 0/12 0/13 0/13 5 No Vaccine 100 12/12 12/12 5/12 Bodyweight and Protection (Clinical Signs and Microscopic Pathology) Data After Challenge of Chickens Vaccinated via the Ocular Route 1 TCO Commercial 618 0/5 0/5 0/5 2 CEO Commercial 704 0/5 0/5 0/5 3 P32 37 C. 626 0/5 0/5 0/5 4 P32 30 C. 716 0/5 0/5 0/5 5 No Vaccine 100 12/12 12/12 5/12 Bodyweight and Protection (Clinical Signs and Microscopic Pathology) Data After Challenge of Chickens Vaccinated via the Oral Route 1 TCO Commercial 716 0/8 0/8 0/8 2 CEO Commercial 715 0/8 0/8 0/8 3 P32 37 C. 708 0/8 0/8 0/8 4 P32 30 C. 753 0/7 0/8 0/8 5 No Vaccine 100 12/12 12/12 5/12

(17) All vaccines induced protection as measured by weight gain from days 1-6 after challenge, the lack of clinical disease signs, and microscopic pathology observed after ocular and intratracheal route challenge with the virulent USDA challenge strain of ILTV. The Animal and Plant Health Inspection Service of the USDA provides the challenge strain to researchers for the purpose of evaluating immunity of chickens following vaccination with experimental and/or commercial vaccines. It is thus a standard strain used for challenge purposes.

(18) Chickens vaccinated with the P32 30C vaccine showed the greatest weight gain, indicating that the broilers were protected. Clinical disease signs observed only in the broilers in the No Vaccine treatment included conjunctival swelling and reddening, presence of an ocular and/or nasal (nares) exudate, labored breathing and coughing. Microscopic pathology of eyelid and trachea was performed to determine whether clinical signs of ILTV infection associated with the virulent challenge were present in these tissues.

(19) Thus, the data in Tables 1-3 demonstrate that the P32 30C vaccine is more attenuated than the other vaccines, based on its ability to produce milder clinical signs. The P32 30C vaccine, however, produced body weight suppression when administered by the oral route, the most common method of vaccine application in commercial practice. For this reason, we decided to clone the P32 30C vaccine using a limit dilution procedure. The limit dilution procedure (Example 2) produced Clone 5-7. Clone 5-7 was evaluated and the results are provided in Tables 4-6. Three serial ten-fold dilutions (10.sup.1, 10.sup.2, and 10.sup.3) of the virus stock were used to vaccinate broiler chickens at two weeks of age. Vaccines were administered by the ocular or oral route.

(20) TABLE-US-00004 TABLE 4 Post-vaccination assessment of varying dilutions (10.sup.1-10.sup.3) of ILTV experimental vaccine Clone 5-7 in two-week-old broiler chickens vaccinated by the ocular or oral route. Weight Gain From 1-6 Days Post Vaccination Clinical Disease as a % of Non-Vacc. Signs Associated Group Treatment Weight Gain With Vaccination Combined Bodyweight Data Following Ocular or Oral Vaccination 1 Clone 5-7 94 2/10 Dilution 10.sup.1 2 Clone 5-7 92 0/12 Dilution 10.sup.2 3 Clone 5-7 101 0/12 Dilution 10.sup.3 4 No Vaccine/ Not Applicable Not Applicable Challenge 5 No Vaccine/ 100 Not Applicable No Challenge Bodyweight Data Post Ocular Vaccination 1 Clone 5-7 103 0/5 Dilution 10.sup.1 2 Clone 5-7 94 0/5 Dilution 10.sup.2 3 Clone 5-7 100 0/5 Dilution 10.sup.3 4 No Vaccine/ Not Applicable Not Applicable Challenge 5 No Vaccine/ 100 Not Applicable No Challenge Bodyweight Data Post Oral Vaccination 1 Clone 5-7 85 2/5 Dilution 10.sup.1 2 Clone 5-7 86 0/5 Dilution 10.sup.2 3 Clone 5-7 101 0/5 Dilution 10.sup.3 4 No Vaccine/ Not Applicable Not Applicable Challenge 5 No Vaccine/ 100 Not Applicable No Challenge

(21) Clone 5-7 dilutions given ocularly had minimal impact on chickens 1-6 days post vaccination. Oral administration reduced weight gain at the 10-1 and 10-2 dilutions, but not at the 10-3 dilution. Clinical disease signs were only observed at the highest oral dose (10.sup.1 dilution.

(22) Chickens receiving the 10.sup.3 dilution of the vaccine were free of clinical signs and gained bodyweight at the same rate as chickens not receiving the vaccine or the virulent challenge (No Vaccine/No Challenge treatment). Thus, Clone 5-7 demonstrated the potential to be a safe and economically desirable vaccine candidate.

(23) TABLE-US-00005 TABLE 5 Post-vaccination assessment of dilutions 10.sup.1 to 10.sup.3 of ILTV experimental vaccine Clone 5-7 in two-week-old broiler chickens vaccinated by the ocular or oral routes. LT Antibody Serology- Day 14 Post Vaccination # of Birds Q-PCR Values- Day 6 ELISA w/Positive # of Birds # of Birds Post Vaccination Titers: Titer: ELISA w/Positive ELISA w/Positive Combined Combined Combined Titers: Titer: Titers: Titer: Group Treatment Group Ocular Oral Group Group Ocular Ocular Oral Oral 1 Clone 5-7 Dilution 10.sup.1 39.2 41.8 36.7 894 6/9 451 2/4 1211 4/5 2 Clone 5-7 Dilution 10.sup.2 37.4 40.9 32.7 786 9/12 584 4/7 1189 4/5 3 Clone 5-7 Dilution 10.sup.3 37.8 37.0 41.4 368 6/12 334 2/7 295 2/5 4 No Vaccine/Challenge Not Not Not 17 0/14 17 0/14 17 0/14 Detected Detected Detected 5 No Vaccine/No Challenge N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A = Not Applicable

(24) Again, quantitative (Q)-PCR values are an indication of the presence of ILTV vaccine in the oral/pharyngeal cavity, a site where the vaccine may be detected. Values are inversely related to virus genome levels; Lower Q-PCR values equate to the presence of higher virus genome levels. Regardless of the type of vaccine tested, ILTV was not detected in great quantities on Day 6 post-vaccination. A difference of 3.0 between Q-PCR values represents a 10-fold difference in the level of detectable viral genome. Chickens vaccinated with the dilutions of the Clone 5-7 vaccine showed a low level of ILTV in the oral/pharyngeal cavity suggesting the vaccine is attenuated.

(25) Serum antibody titers for ILTV were measured on day 14 post-vaccination using a commercial ELISA kit (Synbiotics Corp., Kansas City, Mo.). Fifty percent or more of chickens vaccinated with the Clone 5-7 vaccine via the ocular or oral route (see Combined Group) produced an ILTV serum antibody response. In each vaccine dilution treatment group, ILTV antibodies were detected in the majority of birds. The data show a greater antibody response in birds receiving the 10.sup.1 and 10.sup.2 dilution vaccines orally compared to chickens given the vaccines via the ocular route. Chickens not given the vaccine (No Vaccine/Challenge treatment) did not produce ILTV serum antibody responses. Once again, however, ELISA titers may not correlate well with protection (Fahey et al. 1990. J. Gen. Virol. 71:2401-2405).

(26) TABLE-US-00006 TABLE 6 Post-challenge assessment of dilutions 10.sup.1 to 10.sup.3 of ILTV Clone 5-7 vaccine in two-week-old broiler chickens vaccinated by the ocular or oral route. Weight Gain From 1-6 Days Post Vaccination Clinical Disease As a % of Non-Vacc. Signs Associated Group Treatment Weight Gain With ILTV Infection Combined Bodyweight & Clinical Disease Signs Data Following Ocular or Oral Vaccination 1 Clone 5-7 99 1/8 Dilution 10.sup.1 2 Clone 5-7 92 0/10 Dilution 10.sup.2 3 Clone 5-7 105 1/8 Dilution 10.sup.3 4 No Vaccine/ 61 5/5 Challenge 5 No Vaccine/ 100 0/10 No Challenge Combined Bodyweight & Clinical Disease Signs Data Following Ocular Vaccination 1 Clone 5-7 123 1/3 Dilution 10.sup.1 2 Clone 5-7 94 0/5 Dilution 10.sup.2 3 Clone 5-7 140 1/4 Dilution 10.sup.3 4 No Vaccine/ 61 5/5 Challenge 5 No Vaccine/ 100 0/10 No Challenge Combined Bodyweight & Clinical Disease Signs Data Following Oral Vaccination 1 Clone 5-7 97 0/5 Dilution 10.sup.1 2 Clone 5-7 106 0/5 Dilution 10.sup.2 3 Clone 5-7 99 0/4 Dilution 10.sup.3 4 No Vaccine/ 61 5/5 Challenge 5 No Vaccine/ 100 0/10 No Challenge

(27) After challenge with virulent USDA challenge strain of ILTV, chickens receiving any ILTV Clone 5-7 vaccine dilution had higher weight gain than non-vaccinated/challenged chickens (No Vaccine/Challenge treatment). Following challenge, chickens vaccinated via the ocular or oral routes had fewer clinical disease signs compared to chickens not receiving a vaccination. All chickens vaccinated via the ocular route were protected against clinical disease signs after challenge.

(28) TABLE-US-00007 TABLE 7 Post-vaccination assessment of 10.sup.2 dilution of ILTV experimental vaccine Clone 5-7 in five-week-old specific pathogen-free (SPF) chickens vaccinated by the ocular route. Passage 1 and Passage 2. Clinical Disease Signs Observed Bird During 14 Days Q-PCR Ct Value: Number Vaccinated Before Challenge Oral Swabs 5 DPV Passage 1. Oral Vaccine Shed Following Ocular Vaccination Y41 Yes None 32.7* Y42 Yes None 32.5* Y43 Yes None 33*.sup. Y44 Yes None Undetermined Y45 Yes None 35.3 Y46 Yes None 34.5 Y47 Yes None 30.1* Y48 Yes None 35.0 Y49 Yes None 32.4* Y50 Yes None Undetermined Passage 2. Oral Vaccine Shed Following Ocular Vaccination G61 Yes None Undetermined G62 Yes None Undetermined G63 Yes None Undetermined G64 Yes None Undetermined G65 Yes None Undetermined G66 Yes None Undetermined G67 Yes None Undetermined G68 Yes None Undetermined G69 Yes None Undetermined G70 Yes None Undetermined Inoculum Ct Value of 28 (Clone 5-7 diluted 10.sup.2 or 1:100). *Used in pool for Passage 2 inoculum.

(29) In Passage 1, five days post ocular vaccination with the ILTV Clone 5-7 vaccine, minimal shedding was observed in oral swabbings. In Passage 2, virus was not detected five days post vaccination with material collected from Passage 1 birds.

(30) TABLE-US-00008 TABLE 8 Post-challenge assessment of 10.sup.2 dilution of ILTV experimental vaccine Clone 5-7 in five-week- old specific pathogen-free (SPF) chickens vaccinated by the ocular route. Passage 1 and Passage 2. Bird Num- Clinical Disease Signs Observed: Days Post Challenge ber Vacc. 1 2 3 4 5 6 7 8 9 10 Passage 1. Post Challenge Data Y41 Yes None None None None None None None None None None Y42 Yes None None None None None None None None None None Y43 Yes None None None None None None None None None None Y44 Yes None None None None None None None None None None Y45 Yes None None None None None None None None None None Y46 Yes None None None None None None None None None None Y47 Yes None None None None None None None None None None Y48 Yes None None None None None None None None None None Y49 Yes None None None None None None None None None None Y50 Yes None None None None None None None None None None B26 No None None None Wet Eye (+1).sup.A Conj. (+3).sup.B Conj. (+3) Wet Eye (+1) None None None B27 No None None None Wet Eye (+1) Conj. (+2) Wet Eye (+1) None None None None B28 No None None None Wet Eye (+1) None Wet Eye (+1) None None None None B29 No None None None Wet Eye (+1) Conj. (+3) Conj. (+3) None None None None B30 No None None None Wet Eye (+1) None None None None None Normal Passage 2. Post Challenge Data G61 Yes None None None None Conj. (NS).sup.C Conj. (NS) Conj. (NS) None None None G62 Yes None None None Wet eye (+1),.sup. Conj. (NS) Conj. (NS) None None None None NE.sup.A G63 Yes None None None None Conj. (NS) Conj. (NS) None None None None G64 Yes None None None Conj. (+1).sup.B Conj. (NS) Conj. (NS) Conj. (NS) None None None G65 Yes None None None Wet eye (+1).sup. Conj. (NS) Conj. (NS) None None None None G66 Yes None None None Conj. (+1) Conj. (NS) Conj. (NS) None None None None G67 Yes None None None None Conj. (NS) Conj. (NS) None None None None G68 Yes None None None Conj. (+1) Conj. (NS) Conj. (NS) None None None None G69 Yes None None None Wet eye Conj. (NS) Conj. (NS) None None None None G70 Yes None None None Conj. (+2) Conj. (NS) Conj. (NS) Conj. (NS) None None None P16 No None None None Conj. (+1) Conj. (NS) Conj. (NS) Conj. (NS) Conj. (NS) Wet eye (NS) None P17 No None None None Wet eye (+1).sup. Conj. (NS) Conj. (NS) None None None None P18 No None None None None Conj. (NS) Conj. (NS) None None None None P19 No None None None None Conj. (NS) Conj. (NS) None None None None P20 No None None None Conj. (+2) Conj. (NS) Conj. (NS) Conj. (NS) None None None .sup.AObserved clinical disease signs (severity of clinical disease sign: +1 = mild; +2 = moderate; +3 = severe). .sup.BConj. = Conjunctivitis .sup.CNS = Not Scored

(31) In Passage 1, following challenge with the ILTV USDA challenge strain, all chickens vaccinated via the ocular route with ILTV Clone 5-7 were protected against clinical disease signs compared to chickens not receiving a vaccination. In Passage 2, there was no difference between birds vaccinated with the oral swab material collected in Passage 1 and the non-vaccinated birds. All birds in Passage 2 showed clinical disease signs compatible with ILTV induced disease. These results show that the ILTV Clone 5-7 is able to induce protective immunity (Passage 1) and does not spread to nave susceptible chickens.

(32) Thus, this disclosure describes an attenuated infectious laryngotracheitis virus (ILTV) that may be used as a component in a vaccine to immunize a subject against infection by a virulent infectious laryngotracheitis virus. Generally, the attenuated ILTV can be produced by serial passage at a temperature that is reduced from the temperature at which the ILTV is typically grown. Once the attenuated ILTV is so generated, however, one can generate the attenuated ILTV using conventional molecular biology techniques to produce a virus having the same nucleotide and/or functional features of the attenuated ILTV produced as described herein.

(33) While described herein in the context of an exemplary embodiment in which the attenuated ILTV is produced by serial passaging an ILTV virus, the attenuated ILTV described hereinand variants thereofcan be produced by any suitable method. Also, while expressly exemplified herein in the context of an exemplary embodiment in which the attenuated ILTV possesses each of the genetic modifications listed in Table 11, an attenuated ILTV as described herein may contain fewer than all of the genetic mutations listed in Table 11 and still retain an attenuated character.

(34) In some embodiments, the attenuated ILTV can be produced by serial passage of the virus at a minimum temperature of at least 25 C. such as, for example, at least 27 C., at least 28 C., at least 29 C., at least 30 C., at least 31 C., or at least 32 C. In some embodiments, the attenuated ILTV can be produced by serial passage of the virus at a maximum temperature of no more than 35 C. such as, for example, no more than 34 C., no more than 33 C., no more than 32 C., no more than 31 C., no more than 30 C., or no more than 29 C. In some embodiments, the attenuated ILTV can be produced by serial passage of the virus at a temperature within a range having endpoints defined by any minimum temperature listed above and any maximum temperature that is greater than the minimum temperature. For example, in one embodiment, the attenuated virus can be produced by serial passage of virus at a temperature of from 28 C. to 31 C. In one particular embodiment, the attenuated ILTV can be produced by serial passage of the virus at a temperature of 30 C.

(35) The attenuated ILTV can be generated by any suitable number of serial passages. In some embodiments, the attenuated ILTV can be produced by a method that includes a minimum of at least two serial passages of the virus such as, for example, at least three serial passages, at least five serial passages, at least seven serial passages, at least 15 serial passages, at least 25 serial passages, at least 30 serial passages, at least 34 serial passages, at least 40 serial passages, or at least 45 serial passages. In some embodiments, the attenuated ILTV can be produced by a method that includes a maximum of no more than 50 serial passages such as, for example, no more than 44 serial passages, no more than 30 serial passages, no more than 20 serial passages, no more than 10 serial passages, no more than seven serial passages, no more than five serial passages, no more than four serial passages, or no more than three serial passages. In some embodiments, the attenuated ILTV can be produced by a method that includes a number of serial passages within a range having endpoints defined by any minimum number of passages listed above and any maximum number of serial passages that is greater than the minimum number of serial passages. In one particular embodiment, the attenuated ILTV may be generated using a method that includes seven serial passages of the virus. Thus, in some embodiments, the attenuated virus can be produced by a method that includes, for example, 30-50 serial passages such as, for example, 34-44 serial passages.

(36) The serial passaging of the virus at a reduced temperature produces an attenuated virus that includes one or more genetic modifications compared to the ILTV that was the starting material. In the exemplary embodiment described above, the starting ILTV was a commercially available ILTV of tissue culture origin, LT-IVAX (Merck Animal Health, Summit, N.J.). Table 11 lists genetic modifications of the Clone 5-7 generated as described herein compared to the LT-IVAX. Some of the mutations are located in non-coding regions. Others, however, introduce frame shift mutations or amino acid substitutions

(37) As noted above, while exemplified herein in the context of an exemplary embodiment in which the attenuated ILTV possesses each of the genetic modifications listed in Table 11, the attenuated ILTV contemplated herein may contain fewer than all of the genetic mutations listed in Table 11 and still retain an attenuated character. Exemplary genetic modifications can produce, for example, a frame shift mutation in one or more coding regions of the viral genome. Exemplary coding regions that may be affected by a frame shift mutation include, for example, ORF B, ORF F, UL50, UL7, or UL9.

(38) A frame shift mutation in ORF B may include, for example, a frame shift introduced at Phe54 such as may be produced by a deletion of a nucleotide or an addition of a nucleotide in the codon for Phe54 of ORF B. One exemplary mutation is a deletion of a thymine (e.g., the thymine at nucleotide position 23030 of the ILTV genome) from the codon, but a person of ordinary skill in the art can readily conceive of other mutations that could cause a frame shift at Phe54or any other siteof ORF B.

(39) A frame shift mutation in ORF F may include, for example, a frame shift introduced at Glu233 such as may be produced by a deletion of a nucleotide or an addition of a nucleotide in the codon for Glu233 of ORF F. One exemplary mutation is an addition (e.g., a guanine added between nucleotide position 5377 and 5378 of the ILTV genome) in the codon, but a person of ordinary skill in the art can readily conceive of other mutations that could cause a frame shift at Glu233or any other siteof ORF F.

(40) A frame shift mutation in UL50 may include, for example, a frame shift introduced at Asn10 such as may be produced by a deletion of a nucleotide or an addition of a nucleotide in the codon for Asn10 of UL50. One exemplary mutation is a deletion of a thymine (e.g., a deletion of the thymine at nucleotide position 15577 of the ILTV genome) from the codon, but a person of ordinary skill in the art can readily conceive of other mutations that could cause a frame shift at Asn10or any other siteof UL50.

(41) A frame shift mutation in UL7 may include, for example, a frame shift introduced at Phe104 such as may be produced by a deletion of a nucleotide or an addition of a nucleotide in the codon for Phe104 of UL7. One exemplary mutation is a deletion of a adenine (e.g., the adenine at nucleotide position 98125 of the ILTC genome) from the codon, but a person of ordinary skill in the art can readily conceive of other mutations that could cause a frame shift at Phe104or any other siteof UL7.

(42) A frame shift mutation in UL9 may include, for example, a frame shift introduced at PGlu771 such as may be produced by a deletion of a nucleotide or an addition of a nucleotide in the codon for Glu771 of UL9. One exemplary mutation is a deletion of a adenine (e.g., the adenine at nucleotide position 94565 of the ILTV genome) from the codon, but a person of ordinary skill in the art can readily conceive of other mutations that could cause a frame shift at Glu771or any other siteof UL9.

(43) In some embodiments, an attenuated ILTV can include a genetic modification to the UL50 coding region without necessarily possessing any of the other genetic modifications shown in Table 11. Moreover, in some embodiments, the genetic modification to UL50 may differ from the thymine deletion identified in Table 11, while still resulting in attenuation of the resulting genetically-modified ILTV.

(44) The attenuated ILTV, when administered to a subject, can decrease the likelihood, extent, and/or severity of infection of the subject by a virulent ILTV compared to a comparable unvaccinated control subject. In some cases, administering the attenuated ILTV can result in increased weight gain and/or a decrease in the severity of one or more signs of infection by a virulent ILTV. Exemplary signs of infection by a virulent ILTV include, for example, conjunctival swelling and/or reddening, presence of an ocular and/or nasal (nares) exudate, nasal sinus swelling, labored breathing, coughing, and in severe cases, a bloody expectoration.

(45) Thus, in another aspect, this disclosure describes a method that involves administering the attenuated infectious laryngotracheitis virus described herein to a subject having or at risk of having an ILTV infection.

(46) Thus, treating a condition can be prophylactic or, alternatively, can be initiated after the subject exhibits one or more symptoms or clinical signs of the condition. As used herein, the term sign or clinical sign refers to an objective physical finding relating to a particular condition capable of being found by one other than the subject; the term symptom refers to any subjective evidence of disease or of a subject's condition. Treatment that is prophylactice.g., initiated before a subject manifests a symptom or clinical sign of the condition such as, for example, while an infection remains subclinicalis referred to herein as treatment of a subject that is at risk of having the condition. As used herein, the term at risk refers to a subject that may or may not actually possess the described risk. Thus, for example, a subject at risk of having an infectious condition is a subject present in an area where other individuals have been identified as having the infectious condition and/or is likely to be exposed to the infectious agent. A subject may be at risk even if the subject has not yet manifested any detectable indication of infection by a virulent ILTV and regardless of whether the animal may harbor a subclinical amount of a virulent ILTV.

(47) Accordingly, the attenuated ILTV can be administered to a subject before, during, or after the subject first comes in contact with a virulent ILTV. Treatment initiated after the subject first exhibits comes in contact with a virulent ILTV may result in decreasing the severity of symptoms and/or clinical signs of the condition, completely resolving the condition, and/or decreasing the likelihood of experiencing clinical evidence of the condition compared to a subject to which the attenuated ILTV has not been administered.

(48) The method includes administering an effective amount of the attenuated ILTV to a subject exposed to, or at risk of being exposed to ILTV. In this aspect of the invention, an effective amount is an amount effective to reduce, limit progression, ameliorate, or resolve, to any extent, the symptoms or clinical signs related to infectious laryngotracheitis.

(49) The attenuated ILTV described herein may be formulated in a composition along with a carrier. As used herein, carrier includes any solvent, stabilizer, dispersion medium, vehicle, coating, diluent, antibacterial, and/or antifungal agent, isotonic agent, absorption delaying agent, buffer, carrier solution, suspension, colloid, and the like. The use of such media and/or agents for pharmaceutical active substances is well known in the art. Except insofar as any conventional media or agent is incompatible with the attenuated ILTV described herein, its use in a therapeutic compositions is contemplated. Supplementary active ingredients also can be incorporated into the compositions.

(50) By pharmaceutically acceptable is meant a material that is not biologically or otherwise undesirable, i.e., the material may be administered to an individual along with the attenuated ILTV without causing any undesirable biological effects or interacting in a deleterious manner with any of the other components of the pharmaceutical composition in which it is contained.

(51) The attenuated ILTV may be administered to any suitable subject such as, for example, chickens, turkeys, ducks, pheasants, and peafowl.

(52) In the preceding description, particular embodiments may be described in isolation for clarity. Unless otherwise expressly specified that the features of a particular embodiment are incompatible with the features of another embodiment, certain embodiments can include a combination of compatible features described herein in connection with one or more embodiments.

(53) For any method disclosed herein that includes discrete steps, the steps may be conducted in any feasible order. And, as appropriate, any combination of two or more steps may be conducted simultaneously.

(54) The present invention is illustrated by the following examples. It is to be understood that the particular examples, materials, amounts, and procedures are to be interpreted broadly in accordance with the scope and spirit of the invention as set forth herein.

EXAMPLES

Example 1

Generating P32 37C

(55) The P32 37C virus was serially passaged 32 times in primary chicken embryo kidney cells (CEKC), incubated at 37 C.

(56) Kidney cells were prepared from 17-20 day old embryos.

(57) The amounts indicated here are for preparing kidney cells from 10-15 embryos. Eggs were sprayed with a disinfectant (BIOGUARD, Bioguard Hygiene Solutions Ltd., Northampton, UK) and allowed to dry. Kidneys were dissected from the embryos, washed in Phosphate Buffered Saline (PBS) without calcium or magnesium (1.60 g Na.sub.2HPO.sub.4, 0.51 g KH.sub.2PO.sub.4, 7.30 g NaCl in 1 L DDH.sub.2O). The kidneys were dissociated and treated with trypsin solution (0.25% trypsin in modified PBS+0.02% EDTA, pH 7.4-7.6) and stirred slowly for 15-20 minutes at 37 C. The supernatant was collected by pouring through a gauze-covered funnel into a graduated centrifuge tube with 5 ml of cold (ice bath-cooled) heat-inactivated calf serum. The remaining pellet was retrypsinized with fresh trypsin solution and the process repeated two more times. The collected supernatant was centrifuges at 1500 RPM for 10 minutes. The pelleted kidney cells were resuspended in 3-6 ml minimal essential medium (MEM), then added to MEM with 10% heat-inactivated fetal calf serum.

(58) Cells were counted in a hemacytometer by resuspending in a known amount of media. 2 ml of cells (2.510.sup.6 cells/ml) were plated on a 35 mm.sup.2 plate, which formed a monolayer in 1-2 days. When the monolayer formed, the cells were ready for inoculation.

(59) 1 mL of starting virus was used to infect one 25 mL flask with 80% confluent monolayer of CEKC's. The inoculated CEKC were incubated at 37 C. ILTV cytopathic effect (CPE) known as syncytia were observed in the CEKC at two days after inoculation. The cells and culture media were harvested and repassaged serially for 32 passages at an incubation temperature of 37 C. A seed stock of the virus was then prepared for further experimentation.

(60) Generating P32 30C

(61) The P32 30C virus was serially passaged 32 times in primary chicken embryo kidney cells (CEKC). Cells were prepared as described above for the preparation of the P32 37C virus, except that the inoculated CEKC were incubated at 30 C. ILTV cytopathic effect (CPE) known as syncytia were observed in the CEKC at 3-4 days after inoculation. The cells and culture media were harvested and repassaged serially for 32 passages at an incubation temperature of 30 C. A seed stock of the virus was then prepared for further experimentation.

(62) Assessment of Vaccines

(63) One-day-old, female commercial broiler chickens (Moyer's Chicks, Inc., Quakertown, Pa.) were assigned to one of five treatment groups shown in Table 9.

(64) TABLE-US-00009 TABLE 9 Group Immunizing Vacc. No. of Birds No. Virus Titer (Oral/ED) 1 TCO Vaccine.sup.A 10.sup.3.0 10/5 2 CEO Vaccine.sup.B 10.sup.4.0 10/5 3 P32 30 C..sup.C 10.sup.3.0 10/5 4 P32 37 C..sup.D 10.sup.3.0 10/5 5 Negative Control Sham 10/5 .sup.ATCO = Tissue culture origin (LT-IVAX, Merck Animal Health, Summit, NJ). .sup.BCEO = Chicken embryo origin (TRACHIVAX, Merck Animal Health, Summit, NJ). .sup.CP32 30 C. = 32 tissue culture passages performed at 30 C. .sup.DP32 37 C. = 32 tissue culture passages performed at 37 C.

(65) The night prior to vaccination at 14 days of age, water was withheld from the birds. On the afternoon prior to vaccination, all birds were weighed. Birds in the oral vaccinated groups received 1.5 mL of water containing one drop of vaccine (0.03 ml) by hand using a blunt needle and syringe. Vaccination occurred slowly to ensure proper uptake by the bird. Each bird was held vertically, beak pointed slightly toward the ceiling to mimic drinking from a nipple. Each bird in the corresponding eye drop vaccine group was vaccinated by placing one drop (0.03 ml) of inoculum directly into the conjunctival sac.

(66) Birds were observed daily for signs of vaccine reaction (conjunctivitis, nasal discharge). Six days post vaccination, all birds were weighed. Oropharyngeal swabs were collected from all birds to determine the level of ILTV present in the oral cavity by real-time PCR (Callison et al., 2007. J. Virol. Methods 139:31-38). Two birds from each water vaccinated group and the negative control group were euthanized. Trachea and eyelid were collected for evaluation of microscopic pathology.

(67) Fourteen days post vaccination, all birds were weighed, serum samples were collected from all birds prior to challenge with the USDA challenge strain of ILTV (10.sup.3.5/0.1 ml). ILTV serum antibody titers were evaluated using a commercial ELISA kit (Synbiotics Corp., Kansas City, Mo.). Five days post challenge birds were weighed and evaluated for signs of disease. Trachea and eyelid were collected after euthanizing via cervical dislocation.

(68) Results are shown in Tables 1-3.

Example 2

Generating Clone 5-7 from P 32 30C Using the Limit Dilution Procedure

(69) Serial 10-fold dilutions (10.sup.1-10.sup.6) of the P32 30C virus were prepared and inoculated onto CEKC. The inoculated cells were incubated at 30 C. The CEKC were observed microscopically daily for syncytia. Cells and media were harvested from the highest dilution showing syncytia. A culture plate at the 10.sup.5 dilution, 7.sup.th replicate plate met the criteria and the cells and media were harvested. A seed stock was prepared for further experimentation.

(70) Assessment of Vaccines

(71) Female broiler type chickens (Moyer's Chicks, Inc., Quakertown, Pa.). Chicks were placed in isolation in groups of 13 birds. At 20 days of age, birds were water deprived for at least two hours prior to inoculation. The following day, at 21 days of age, birds were randomly regrouped, assigned to treatment groups (Table 10) and necktagged for identification. All birds were weighed. Birds with bodyweights greater than or less than 2SD of the group mean weight were used in the swab control groups. The negative control birds were placed in isolation prior to handling any viruses. Birds in the negative control/oral group received 1 mL of water. No other sham inoculations were performed.

(72) TABLE-US-00010 TABLE 10 Cage No. of Female No. Treatment Treatment Broilers 1 Negative Challenge Controls 5 Control Oral 5 Ocular 5 Swab Controls 2 2 10.sup.1 Oral 5 Ocular 5 3 10.sup.2 Oral 5 Ocular 5 Swab Controls 2 4 10.sup.3 Oral 5 Ocular 5 Swab Controls 2 5 10.sup.4 Oral 5 Ocular 5 Swab Controls 2 6 10.sup.5 Oral 5 Ocular 5 Swab Controls 2 7 10.sup.6 Oral 5 Ocular 5 Swab Controls 2
Inoculation:

(73) Prior to inoculation with the Clone 5-7 dilutions, all birds were weighed and blood samples were collected from 10 birds. Six 8-ml tubes were filled with 4.5 ml of sterile water (pH 7.0spring water). Tubes were used for to create the inoculum dilutions (10.sup.1 to 10.sup.6). Six 10-fold dilutions of the Clone 5-7 ILTV were created by placing 0.5 ml of virus in 4.5 ml of sterile water (pH 7.0spring water). 0.5 ml of the 10.sup.1 dilution was then be placed into 4.5 ml of sterile water (pH 7.0spring water) to create the 10.sup.2 and repeated until the 10.sup.6 dilution was created. 0.5 ml were removed from the 10.sup.6 dilution and discarded. All dilution tubes contained 4.5 ml of the virus/water dilution.

(74) Two separate tubes were marked as either for ocular or oral inoculation. The ocular tube contained at least 1 ml of the given dilution. The oral tube contained 0.7 ml of inoculum and 7 ml of water. These tubes were held on ice until used. Ocular treatment birds received 0.1 ml (100 l) by eyedrop. The oral treatment birds received 1 ml of the water/virus preparation. Swab controls received 0.1 ml (100 l) of a given vaccine treatment via eyedrop. These birds were used to assess viral load in the trachea by real-time PCR.

(75) 6 DPI Swab and Weigh:

(76) Birds were swabbed at six day post-inoculation (dpi) to determine viral load by real time PCR in the oral cavity of the ocular and oral challenged groups. Tracheal and oral swabs were collected from the swab controls to evaluate viral load at both swabbing locations by real-time PCR (Callison et al., 2007. J. Virol. Methods 139:31-38). Body weights were also collected to determine the effect of infection on weight gain. Swabs were collected and placed in 2 ml of sterile Tryptose Phosphate Broth (Difco, BD Biosciences, San Jose, Calif.).

(77) 14 DPI-Challenge:

(78) All birds were weighed and bled prior to challenge. The five challenge controls in cage 1 were used to verify infection of the broilers using challenge dose of 10.sup.3 per bird. After challenge, the challenge controls were relocated among the 10.sup.5 and 10.sup.6 treatment groups (cages 6 and 7). All birds in cages 2-7 received a challenge of 10.sup.3 EID.sub.50 of the USDA ILTV challenge strain per 0.1 ml divided between the intraocular (one drop) and oral (remaining volume up to 0.1 ml) routes of inoculation using a 200 l pipette.

(79) Birds were evaluated daily for signs of clinical disease for a period of 10 days post challenge (DPC). At 6 DPC, birds were weighed to evaluate protection based upon suppression of daily weight gain compared to non-challenged controls. At 10 DPC, birds were weighed and evaluated for signs of clinical disease. All surviving birds were bled to evaluate ILTV antibody status following challenge. ELISA titers were evaluated to determine if they might be indicative of lack of protection or a booster response. The experiment was terminated after 10 DPC.

(80) Results are shown in Tables 4-6.

(81) Genetic Signature of Clone 5-7

(82) Approximately 500 L of the Clone 5-7 TCO supernatant was treated with DNase and the viral DNA was extracted using the DNeasy 96 Blood & Tissue Kit (Qiagen, Inc., Valencia, Calif.) according the recommended procedures. A DNA library was generated using the NuGen OVATION ultralow library system (NuGEN Technologies, Inc., San Carlos, Calif.). The libraries were sequenced on an Illumina Genome Analyzer IIx (Illumina, Inc., San Diego, Calif.) in a paired-end, 101 cycle run. Library reads were assembled to a reference ILTV genome using CLCWorkbench (CLC bio, Inc., Germantown, Md.). Variant detection within the Clone 5-7 assembled genome and the impact of the detected variation on amino acid sequence was performed within CLCWorkbench (CLC bio, Inc.,).

(83) TABLE-US-00011 TABLE 11 ILTV Clone 5-7 Genetic Signature vs. Commercial TCO Vaccine Depth of Coding Nt TCO ILTV Clone Non-synonymous Amino Acid Coverage at Frequency of Region Position# Vaccine Nt 5-7 Nt or Synonymous Change Position Mutation (%) NC 1160 A Not Applicable Not Applicable 2020 3.81 NC 104594 A Not Applicable Not Applicable 4493 93.08 NC 109606{circumflex over ()}109607 G Not Applicable Not Applicable 1981 72.19 NC 109614 T Not Applicable Not Applicable 980 6.22 NC 109616{circumflex over ()}109617 G Not Applicable Not Applicable 1689 3.02 NC 109622 G Not Applicable Not Applicable 1450 6.55 ORF B 23030 T Non-synonymous Phe54fs* 5030 6.92 ORF F 5377{circumflex over ()}5378 G Non-synonymous Glu233fs 5489 3.06 UL36 53320 A G Non-synonymous Val2300Ala 4082 16.39 UL37 62826 T C Synonymous Not Applicable 4129 3.44 UL50 15577 T Non-synonymous Asn10fs 4582 92.45 UL7 98125 A Non-synonymous Phe104fs 4737 5.3 UL9 94565 A Non-synonymous Glu771fs 4339 5.49 *fs = frame shift #SEQ ID NO: 1, Genbank accession no. JN580312

Example 3

(84) Female specific pathogen free (SPF) leghorn chickens were obtained at five weeks of age from Charles-River SPAFAS (Norwich, Conn.). Birds were periodically obtained in lots of 15 or 30.

(85) Passage 1

(86) For each passage, birds were assigned to one of two groups: Direct Inoculated (10 birds) or Challenge Controls (5 birds) (Table 7 and Table 8). Each bird was tagged according to treatment group. Clone 5-7 was diluted 1:100 and administered via eye-drop (0.1 mL/bird) to each of the 10 birds in Cage 1. On day 5 post challenge (PC), an oropharyngeal swabbing, culminating in the swabbing of the upper tracheal opening, were collected from each bird and placed into two swab tubes (5 swabs in each tube), each containing 2.5 mL of Tryptose Phosphate Broth (Difco, BD Biosciences, San Jose, Calif.) with antibiotics (penicillin (100 I.U.) and streptomycin (100 g/ml), with fungizone (2.5 g/ml)). Tubes were held at 80 C. until need for subsequent challenge.

(87) Birds were observed and scored daily for disease signs (conjunctivitis, labored breathing/gasping, mortality) through day 10 post-direct inoculation. Birds were scored as 0=normal, 1=diseased (respiratory signs, swollen eye), or 2=dead. Swab tubes were screened for the presence of ILTV genome by real-time PCR (Callison et al., 2007. J. Virol. Methods 139:31-38).

(88) Fourteen days post inoculation, the Direct Inoculates (10 birds) and the Challenge Controls (5 birds) were bled to determine ILTV serum antibody status by enzyme-linked immunosorbent assay (ELISA) (Synbiotics Corp., Kansas City, Mo.). All birds were moved to the Clone 5-7 Challenge Cage and challenged via eye-drop with the USDA ILTV Challenge Virus (10.sup.3.5/bird). All birds were evaluated through 10 days PC for disease signs using the same scoring scale defined above.

(89) Passage 2 to Passage 5

(90) On the defined day of challenge, the two swab tubes collected five days post challenge with the previous passage were thawed at room temperature and centrifuged to pellet any debris. An aliquot of 0.5 ml from each tube was taken and pooled to create the inoculum for birds. The 10 birds in the direct inoculation group received 0.1 ml of the undiluted swab pool material via eye-drop. On day 5 post challenge, an oropharyngeal swabbing (culminating in the swabbing of the upper tracheal opening) was collected from each bird and placed into two swab tubes (5 swabs in each tube) each containing 2.5 ml of Tryptose Phosphate Broth (Difco, BD Biosciences, San Jose, Calif.) with antibiotics (penicillin (100 I.U.) and streptomycin (100 g/ml) with fungizone (2.5 g/ml)). Tubes were held at 80 C. until need for subsequent challenge.

(91) Birds were observed and scored daily for disease signs (conjunctivitis, labored breathing/gasping, mortality) through day 10 post-direct inoculation. Birds were scored as described for Passage 1. Swab tubes were screened for the presence of ILTV genome by real-time PCR as described for Passage 1.

(92) Fourteen days post inoculation, the Direct Inoculates (10 birds) and the Challenge Controls (5 birds) were bled to determine ILTV serum antibody status as described for Passage 1. All birds were challenged via eye-drop and evaluated through 10 days post challenge as described for Passage 1.

(93) The inoculation procedure described above was repeated until ILTV was no longer detected by real-time PCR, the birds were susceptible to challenge, or a total of 5 bird passages had been completed.

(94) Results are shown in Tables 7 and 8.

(95) As used herein, the term and/or means one or all of the listed elements or a combination of any two or more of the listed elements; the terms comprises and variations thereof do not have a limiting meaning where these terms appear in the description and claims; unless otherwise specified, a, an, the, and at least one are used interchangeably and mean one or more than one; and the recitations of numerical ranges by endpoints include all numbers subsumed within that range (e.g., 1 to 5 includes 1, 1.5, 2, 2.75, 3, 3.80, 4, 5, etc.).

(96) The complete disclosure of all patents, patent applications, and publications, and electronically available material (including, for instance, nucleotide sequence submissions in, e.g., GenBank and RefSeq, and amino acid sequence submissions in, e.g., SwissProt, PIR, PRF, PDB, and translations from annotated coding regions in GenBank and RefSeq) cited herein are incorporated by reference in their entirety. In the event that any inconsistency exists between the disclosure of the present application and the disclosure(s) of any document incorporated herein by reference, the disclosure of the present application shall govern. The foregoing detailed description and examples have been given for clarity of understanding only. No unnecessary limitations are to be understood therefrom. The invention is not limited to the exact details shown and described, for variations obvious to one skilled in the art will be included within the invention defined by the claims.

(97) Unless otherwise indicated, all numbers expressing quantities of components, molecular weights, and so forth used in the specification and claims are to be understood as being modified in all instances by the term about. Accordingly, unless otherwise indicated to the contrary, the numerical parameters set forth in the specification and claims are approximations that may vary depending upon the desired properties sought to be obtained by the present invention. At the very least, and not as an attempt to limit the doctrine of equivalents to the scope of the claims, each numerical parameter should at least be construed in light of the number of reported significant digits and by applying ordinary rounding techniques.

(98) Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as possible. All numerical values, however, inherently contain a range necessarily resulting from the standard deviation found in their respective testing measurements.

(99) All headings are for the convenience of the reader and should not be used to limit the meaning of the text that follows the heading, unless so specified.

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taggagctttgctccatagttatgggtgcggaatgtgtcagtatttagctattgttatat2220 ttactgggcagggctcgtttatttgcccaaattgagcagctcggactacaatacgaccta2280 caaagagctgacacagcacagtctctaacagctgttcctggagtcatttaaacagaacga2340 taaattcgaactaaatcgggacagtcccttcgcttgcacggagtccaggtaacactgcgg2400 atctgacaataggattggtgagaacaagtgaagatgccagctcccgacacgaactagtga2460 cctagtccagacgaaaatgcttaagcttgtccttgattggacaagcacgatgaaaacgaa2520 accctgcatagatattggcgagctggctctttacacactctgcggatgtagcttagtggg2580 cgggtatcgggtttcgccgcactgccgaacgctgctttgcttcttgctctatctatttta2640 tagccgggcgcttttaaagaatggacttcgagctttgcatgttcttaattactttaattc2700 tagcaattcttttatttttagctatattgtatctacagtgggtccgtcatcgtagagaag2760 ccgcagagaggctgctatttctgcttttaatacacaacattcagaacgatgcgggcttaa2820 gacggaaccgcgcggcacaaggagcataactgcggggtcagtgtttgttgctgcgtggtt2880 gtaattctctttttggcactgcgaggctaggtttgttgccgcgcgattgcagggtttttc2940 tttgtgagactggtgatggggaaaagcttgattgtgcaatagtaaaagtgacttaggtac3000 ttcatatactgggctgtggcatgtaggcacgtccaagctcggctctgaattctaagcttg3060 ctttgtcgaaccagttttgttttctttttggggggagggtagcacactctgcccgagtct3120 cggcattgacttaacagtgatgtgaaacccggaagatcgagcatgaactaatagcattaa3180 agaattgttatccgaggaataatcgtggacgcgaatttactcgaccgctaaaatctttct3240 tctactgagctggatacgtgaaatttggtgagtataacctctcgggatacatagctttta3300 aatacggggcgtgcaatattaaattctgcactcggggctgcaatggagcgcggagcttta3360 tttgacaagaccgccaattgcaaggactgggtctcgatcgggactactgtgtggggcgcg3420 atcgatgcagatgacggggacgacttagtctgggattatgaaaatagcccatatccaagc3480 atagtttcctcactattcccgggggaagaaacggactcggcaatttgtaactctgttgtt3540 gccgcaaacccctgtagcatacctcctgggcggcagcgtttggcatggccatgctgctgt3600 tttcgtcggccagacagcttctccgtcccgcgcgtggaagttaatgctcgccttgttgcc3660 gcggttgcactgataattttctcattgcttgtagtgatctgtgttgcgtcatattggggg3720 taacatgtcttcagaggacacatcgggattcctaacgccccccgcaagtgatgacgacac3780 tgacccttccgagccaccaccaaatttatgggatcctcaccaggacgattttccgaggga3840 cgctgattccccaaacccacttttctacccctgggatgactctgtgaataatactgggga3900 tacgggcagtaacgaagatgactatgtagatatgggaggggtaggtggatccgaagacta3960 tgaagacctcggtacgggcggggactctgactatgacaatgtatctacagcgaccggcgg4020 gacgtggtttccttcccttacttcttggtcatcagaggaccacggcccaacttctccgga4080 aaaccctatgcaacaacttcaagtaacaattcagcaggattcagatccacagcaggaacc4140 cgatccccagcaagttcccggtctccagcaggaacctgacccccagcaagatccacgaga4200 gcctcgtgatcctcctccctatagtccgcccccagaggacccttttgggctctcgccatt4260 tactagtgggatgggcgggtttgggccaccgccacggtggccccagccaccctcgtatga4320 tgaggcaatgggggatggaccttttactacgactgggggtcggcgaccttgctcacgcag4380 gcgcggtcgtcgccggtctcgaggtcgatctcggcgacgcaattggtgtgcagcaaagtt4440 gtgctcagaggcatgtttgtggcatctcttttgggttggagtggccttaatgtgttggtg4500 gctcttgtatcttattttgcgcattgtctggggacagactccgggataaggaaggttgta4560 tccgcatccagtactcctcaataaaagcgtggtggtgctacacgatgtctgttaatttta4620 caactccattttacaggtgatctagagagacgctgagtggcacttgtcccgacgggacc4679 atgcagtcgaacagcagcgatgaggcccagtgtgatgatgtcgaggag4727 MetGlnSerAsnSerSerAspGluAlaGlnCysAspAspValGluGlu 151015 ggatggtcgtccatagctccaggtgatgcactggatacagatttcatt4775 GlyTrpSerSerIleAlaProGlyAspAlaLeuAspThrAspPheIle 202530 ccagggccttgtgccacgtccatacatggtatatccaaggcagtttat4823 ProGlyProCysAlaThrSerIleHisGlyIleSerLysAlaValTyr 354045 ttttttctgtgtggagttaatctggaggaatgtagtacactcccacag4871 PhePheLeuCysGlyValAsnLeuGluGluCysSerThrLeuProGln 505560 catgtccaatctcacccatatggacatcctgagctgaaatcaggcaaa4919 HisValGlnSerHisProTyrGlyHisProGluLeuLysSerGlyLys 65707580 tggtacaagaggttttgctccgggctaggcgaaattggagatacaagc4967 TrpTyrLysArgPheCysSerGlyLeuGlyGluIleGlyAspThrSer 859095 cagtgtcagctgacacgactatgctgcacttccggaatgccggcacag5015 GlnCysGlnLeuThrArgLeuCysCysThrSerGlyMetProAlaGln 100105110 atttttgggccttcgagattcaggtctctgcaacagaagccaacccat5063 IlePheGlyProSerArgPheArgSerLeuGlnGlnLysProThrHis 115120125 atgcgggcccaagatttgctcactaggccttgccatatactagagttc5111 MetArgAlaGlnAspLeuLeuThrArgProCysHisIleLeuGluPhe 130135140 gatgttggcgctgacctaatcaatcttttcttgtatatggaaccatgt5159 AspValGlyAlaAspLeuIleAsnLeuPheLeuTyrMetGluProCys 145150155160 tcagggaatcgatattgcgtacatttaggataccataaaactaatgcc5207 SerGlyAsnArgTyrCysValHisLeuGlyTyrHisLysThrAsnAla 165170175 atgcgtgttttgagcggtggtgggattctatggggcagacttccgtgg5255 MetArgValLeuSerGlyGlyGlyIleLeuTrpGlyArgLeuProTrp 180185190 aaggacaacaccgaggagcacgggtactcgttgcctatgcgagtattt5303 LysAspAsnThrGluGluHisGlyTyrSerLeuProMetArgValPhe 195200205 gggatcaaattgccccataaagtttatgtggcatgtcgctgccctgca5351 GlyIleLysLeuProHisLysValTyrValAlaCysArgCysProAla 210215220 actcggacggaactattatttggtgaggggggggtaggattcaacgcg5399 ThrArgThrGluLeuLeuPheGlyGluGlyGlyValGlyPheAsnAla 225230235240 gaaaactttaaacagtgcggacggttgaaaaaagagtgtgaatgtctg5447 GluAsnPheLysGlnCysGlyArgLeuLysLysGluCysGluCysLeu 245250255 cagaaggcttgttttactgcacaaacggtgttaggtgcggcatataag5495 GlnLysAlaCysPheThrAlaGlnThrValLeuGlyAlaAlaTyrLys 260265270 tttactgtatactcgagcaagggacgaggtcaagaaattctgctatat5543 PheThrValTyrSerSerLysGlyArgGlyGlnGluIleLeuLeuTyr 275280285 tcaggacccatgaatgctacaacggtaatgcctgtagtactgggtatg5591 SerGlyProMetAsnAlaThrThrValMetProValValLeuGlyMet 290295300 ttaagtagagaaccccacaggtgtgcaggtacactcatactgtccagg5639 LeuSerArgGluProHisArgCysAlaGlyThrLeuIleLeuSerArg 305310315320 tcctctggaaattgccgtggatttcatgagacccaacacgatattccc5687 SerSerGlyAsnCysArgGlyPheHisGluThrGlnHisAspIlePro 325330335 actaacccgggtctgtatcctctgtgtaatcatgagcacccttactat5735 ThrAsnProGlyLeuTyrProLeuCysAsnHisGluHisProTyrTyr 340345350 gtgacagttacagatgtatgcggcaactgttgttcatggcttgagcgg5783 ValThrValThrAspValCysGlyAsnCysCysSerTrpLeuGluArg 355360365 gtttttgggagagtagctgcccctgctggtctaagctccgtatctgta5831 ValPheGlyArgValAlaAlaProAlaGlyLeuSerSerValSerVal 370375380 tccattaaaggctccacccacagcgggactgacgtgacagaagaacgt5879 SerIleLysGlySerThrHisSerGlyThrAspValThrGluGluArg 385390395400 gaagaggactcagggacacagcaaacctcccacgacaaattgccggag5927 GluGluAspSerGlyThrGlnGlnThrSerHisAspLysLeuProGlu 405410415 cgcaaccgcatgggagatcaaaattcgaatttgcggggaagagatcaa5975 ArgAsnArgMetGlyAspGlnAsnSerAsnLeuArgGlyArgAspGln 420425430 tattggccgcctgccccacaccgtagtcattgtcactcggattttata6023 TyrTrpProProAlaProHisArgSerHisCysHisSerAspPheIle 435440445 ttcgatgaacctgagccagaaagtggggaagacgtgcataacatgcat6071 PheAspGluProGluProGluSerGlyGluAspValHisAsnMetHis 450455460 cctccacgaggtgcagatgagcaaacagccgcttctgtgtcagcgcta6119 ProProArgGlyAlaAspGluGlnThrAlaAlaSerValSerAlaLeu 465470475480 atgcaaagtctagcacaagcattggtgagtgcacaagctattagcagc6167 MetGlnSerLeuAlaGlnAlaLeuValSerAlaGlnAlaIleSerSer 485490495 atggtctctggctctgcttcctcagtgggcgtagaagtagactgtggg6215 MetValSerGlySerAlaSerSerValGlyValGluValAspCysGly 500505510 tacagtcagactcatattacagaggggccggggagggaacaattcggt6263 TyrSerGlnThrHisIleThrGluGlyProGlyArgGluGlnPheGly 515520525 agagtcccagaaagagggccagagtatcctcaagattactgtgatata6311 ArgValProGluArgGlyProGluTyrProGlnAspTyrCysAspIle 530535540 tatggtcctgtaagtaatgggcctgctggatacagagcaggaccacca6359 TyrGlyProValSerAsnGlyProAlaGlyTyrArgAlaGlyProPro 545550555560 gatgctcctagtatacaagataggaccttcccatgcggcagaagatgc6407 AspAlaProSerIleGlnAspArgThrPheProCysGlyArgArgCys 565570575 gacgaagcatggcttgccttagaagtagggaatatgccttggatttct6455 AspGluAlaTrpLeuAlaLeuGluValGlyAsnMetProTrpIleSer 580585590 tctggttcacatagtccaccttctcagtatcataacccttatggttca6503 SerGlySerHisSerProProSerGlnTyrHisAsnProTyrGlySer 595600605 catagtccaccttcccagtctcataacccttatggtacatatagtccg6551 HisSerProProSerGlnSerHisAsnProTyrGlyThrTyrSerPro 610615620 ccttctcagtctcataacccttatggctcatatagtccgccttcccag6599 ProSerGlnSerHisAsnProTyrGlySerTyrSerProProSerGln 625630635640 tatcataacccttgtggtacatatagtccgccttctcagtctcgtaag6647 TyrHisAsnProCysGlyThrTyrSerProProSerGlnSerArgLys 645650655 catgactattcacctccatatccgatactcaaaccaaagcctcgatta6695 HisAspTyrSerProProTyrProIleLeuLysProLysProArgLeu 660665670 cccccaggctttgaaaatactgctgggatgtggcctcgatgtccccct6743 ProProGlyPheGluAsnThrAlaGlyMetTrpProArgCysProPro 675680685 gggtttgaggggcgtccatacaaatctgggggcatgggtaactttcct6791 GlyPheGluGlyArgProTyrLysSerGlyGlyMetGlyAsnPhePro 690695700 ggaagtgcatggacggtaatagatagggggtctaaccaatggccagca6839 GlySerAlaTrpThrValIleAspArgGlySerAsnGlnTrpProAla 705710715720 gacgtgcgggggccattctcagatcaacgatgggcccccacagagcat6887 AspValArgGlyProPheSerAspGlnArgTrpAlaProThrGluHis 725730735 gaaacgcgacgtttttgcgggtattacagctgagctctcatcatacccataac6940 GluThrArgArgPheCysGlyTyrTyrSer 740745 tccactcataacccaaggcccataaatccataactcataacataaattcatactttccgg7000 tcgtccagggcaccacgtcatcaacaaggattgcagataaataaaaatgctccacgttgt7060 cggtgtccgttgtattgtattctttattatacctccgtaattttcgagagtcggggaaca7120 ttctaaaaattttaaccgtgcaatactacagtgtatttacaaggccggattgcaacagtg7180 aactcattacatcattgagctcgcggcgccatctgctgaccagtccacagagatggcaat7240 cttcagaaacgtaggatggcaccaattccaatacaataccgccatctgtcgataggtgta7300 tagaactgtcaaaacaagtcgcaagagaaaaatttccctactgtatactggcggcttagc7360 agctgcgcacaaaccactctgcattcctctttgcggcacacatttgcgtgctgcgccaga7420 acgagtgggatttttttagaacaggtcccaggatagtacatgtcccacaatgttctggcc7480 gggtctattgctttatgattcatgactatggcctctggtcgcggatacacaattcttgag7540 aaccggtcgaagaaggtcagtaataaagttaaaggacattttgcgctactcagcgatagc7600 tcctgagatctagtggtatctcttagttgactgccaatgctagagagataacacggcagg7660 attggccccagatgcatggctagagattgacatgcgcagtagatgttagagaagatagga7720 tcgtgggggtaaatcctttcatcttcgaactgatgccaaagcatccatacaagtgtctca7780 tcgcatgcaaaaagtagctcttcaaatgagcagttcgccaaatatacagctcgtgaaatt7840 tttgccaacctggctatatccggacgcgatgtccagcggcctttcagtgaagctgcgcgc7900 ccacaaaactgcttccacgaagtgaatgcagcatctgctgcaaggtcagatgatcccgaa7960 gacaaaaatgctggaaagcagattcctctatcacgatcgatatcatcacaatcatcatca8020 tccactgcccggtttaccatgtctaaaagacatttctgattttctaatcttaactcttca8080 gtaatgcactttccgagaccgccaaatgcagttgcggccttttcaaaatattgggccggt8140 gttacgtttcgcaactccttcgtttcggtccgtgatgacgttgggcatcggacaaagtct8200 ctccaaatcggtcttcgaagttcatcccgatttctttcccaagacctgcgcgaatgcttc8260 aacgaaacagtaaagataggcgccctatatcgcttttctggtgtacctgcacggcgcctg8320 ggtctaggggggatgcctcttcggacttggatatgcgcacggcctctcataaacttattt8380 cgagggctactgacccgccttatggaagaccgtacgctcatacctgactggttctcgtaa8440 cgggaacgaggctcgccattcgaatagcgacggcgccccctgtcacgtgaatcacggact8500 cgtttccagctaccgcgcccagatgaccgggatctggagctactttctgtagaatgagat8560 ctgcggcgaatacaatgtgcttcgtggcgggattctgacctcgagcgtgaacggccatcc8620 aggcgatcttttgtcctttccgttgctgatctcgcttcgctatgagtacttgtattggaa8680 gatgatctggaacgtgtctcacgcctatctttatttattccagatttctccggtctcccc8740 atcgcagtcagtgggttgatgtaccgcgtgcacgtcaaaaaaaatgaaaccgcacacaca8800 acggttgagacttctacggactcagaacaggtgtcaagctcggagcaggtgctgagaggt8860 aagctgacagtaatctggcacgctgtttgcgagctaatccacttggcttttgaatggtct8920 gggccactcccagtatacgtcataacacatacactggaacccacaaactacaattgcggt8980 ccagtagttggtgcgaaatattcacgcagacataataatctgcgagaacttctgcggatc9040 cgacatgtaacttaatcccgtaatgtagtgcggcataccgtctaaaccgcaaacatccgc9100 ttagtagaacacgccctaaaatcacccacgagtatactttgtacattctgaccgccagta9160 gttactcctttcaaacaatgatactcagccgttagaactagggctgtcttcaaatggacc9220 aaattcagacacaataccgcacaacgtgttttaacattttattgccgttcaaggcccgaa9280 caatttgttttgtatcttctgttcgtatttaaatgcaattattacaatgctcgcaatcgc9340 agccacgcacaatgcacgcaagactaagctcgaagcaatattggcaaggcatgaagtcaa9400 gatactgggaggtttcgatgcggagactttagtctttgccggagtcgtgtaagggatcag9460 tgataagagttctagaaccgctgagacaattacatatacccaagcactaatttttacgtg9520 ttcatgtaaaatatatgcacacggatcatagcaaatccgcaatgtcatggtggacataat9580 aagcgatgctaaatataaaccgatctcgagtgttttcagtagtaagacccctggattaca9640 gacgcaaaatcctagagggtctgctacgtagttcaagcttttgcaatctcggagatgttc9700 aaattccctcaaaaaccgttgcatctttgtgtatggcacccgtaatatcagcctcgaagt9760 aaacgctgtccagtagttaagatgatatgcatccatcgcaatgcgttctcgcggcagaca9820 tagcccgaacattcgcctctggcgacgggtcagcaagtaacatatgtacaataccgtcga9880 aatgaatgcaactctgatctgggaaaaccatatgtaaagcagacagtctgccacttccat9940 gacgaatactgttctttggccggtgggatcaagacgagaaatgagtacagtctcattttc10000 aaaataagctcctttaacacatctcgtctggtggttctcgtagttgtttagacgctgtgt10060 atattttgtgaggacataaactagtgaagaattaaatgtagcggggggttggtgaacagg10120 attgaattcttgctgtccgggcaggagccatttaatatttgcgagtacgtacaagcagtc10180 gtcctttgagtcagtggaaattttagagcatacataccataccaagaagactatatgtat10240 cgttccggttaaaattactgcccattttagacattctggtcgcagcattctttggtcaga10300 cgcactgtaaactgagtttgcagcgtgttgcctccgcacttagtcgcaaagcatttggtc10360 tgaaatgccgcgtagggattgccctgtgagttaattgcaaccgctacagaagtaatgacg10420 gtctgggcagcggcacttcgatgcgaatgtttaaggcaggtaaaagttgcgcgccctccg10480 caccctcgacgatttcgtaatagtgatgcggtaatgcgcgttttgagcacccgcacgtct10540 ccaaaactaatgtcgctgtattcgtgcgccaacgatggaaaatgctcttttatgtaattt10600 gttatggccggcagaacatatgtcgtgagcacaaagactccatcgatcgtatccaccccg10660 gctcctgtcctgtcttcgcacggtgctaaattgacacgactgaatgcttccgcgaggcta10720 agagacacagccgtttggggcaagttgctagagggttttgaaactccccctataacgtca10780 ggaggacacgcgattcgagtgacgataatatttggggtgggattgtctggacggaaagca10840 tgaaaatggaaattattagggtctttgtgcgctgccgcgaaagctactttatctgcacag10900 tcaggggggaaaattataaacggcaggagtctcccagacatgaatccggattcagaaacc10960 ttggcaaagaaaggtagccggagacttcgtcctggcgagtagattccagtgtcaataaag11020 tcatagtctctgataacatcgtctaaacattcaatgatttcttcctgcagtaaaattacg11080 tgctgagctagcttcgcgatagtttttactgtctctagaccaaacaaagcatatggggat11140 gggattgggacgcagactctgaacccgagcttttctttgcatttgcataaggttgaattg11200 gcacgatcccgaaatacatttaacgcatcctgtaagtcttgaacagagactatggctcca11260 tgttcactcgcatgctcatcacaccatgacatttcttctacccagccgctatcgcagagg11320 tacatgttctcttcgtcttctatgtcatcagaacatgtattctccaaaaaatcaatatcc11380 actgaggaatattgtgcgtcatggctctccggggacgagcagtgacttttgtaaaagtac11440 acgggataggtgtcatgactgattgatgtctccggaaacaataaggctattaattggatc11500 aatgccacgcgcacggcccgcatcgctttatgtaaggtcaacatcgttatggggccgtga11560 tctagcttgaggggtatgtcgatatccagtatcagggattgaattgctagagattcgtta11620 aggacttcattcctattcaggtacatttgtgacagaccgctgcaagatgcccgaatttta11680 tttttcgaactagttccccatgcggtttcgttcattgcactagtccaagcaaagtctatt11740 actggcaacatggcctgatctgcgaggggggcatcactgcgcattagtaagcaggagtcg11800 tgtatgctggtgtcagatcttacatcagcggttataatcgagtcccactcatcgctggca11860 atggctgcaaaagcctgtccgtgtccagccaatgttactctgtaaacgggacatggtccg11920 ttcctagctgttggtggaggaatgcttgtgggtttcagagaatggaataagagtgtcact11980 ggtcgctttccgcaaataacttgatcagatgaaacgagagaaagtaacctacttaaggga12040 gcaaaaatgatatctcctgtcttacagtattgcccgtcgcgctctcttttttgtgcaagg12100 gcgtgtggagcggaagcatcatctccttcctcttcttcctcttcttcctcttcttcctgt12160 tcattgctagatacagtgctcacatttctgaccagcatgtcagccaagtgtgccccgtag12220 cgacagagagtatcggaatatagacggtctatacgcgttgatacatcaaatgcggaacga12280 caaaaaccaagaaaattgcgcccctgtatttcaccgtaagattttatagctgcaaacttc12340 cctgctactacagccggcaatttcatgacttgcatagtcacatgctgtctgaagtacgaa12400 gcaaaattacaacattcccttaagcttttaaaaaaatcactttgagcacgagcagaactc12460 ttaactggattggtgagattttcagaaagacattgcaagtgttctctaatcacgtttcgt12520 ccatatccttcactgtaagctaaatatacaaatgagatgaagtcacgagctggaagccgc12580 agggcatgtctgtatttgcagataagtgcttccaattgttctgaatagcccctgtcggcg12640 ctagtacgtaatctcaaatgatctctgaatagctttgcagattcgcgagtggcatagtag12700 ctgctgcaccagaatttagaaaacgcagagaaggacgttaggcgcgctatagtcaggtta12760 ctcctgttgttgctattctccgtttgaaatgtaatgcatagatcctttactgcttgaagg12820 tcaaacgtcccagcaataccatcgtcaggggttgcttctaacaagtaatatctcatggct12880 gcaacaagggtaatttctgacgggccgaattttgatacgaaccaaaaggggttcgaaaag12940 ttcgagttgtaaagcctcctgtatgcggcaatcacccttgactcatgctgaagcatcagg13000 ccctccagggcaggtcttcctctgggtagagtcgcatgtatggcagaaaaaggaattttg13060 ttggttgtattttctgctcggaaaattactccgagtgcctcaataatgtccgtgtgcaat13120 gcaaatgtttcctccaaatccatggtttccagtaataactttgcatcgattggaaaccct13180 tcggctaaggcttctctcatagttgcggccccttgaccgacaaaacgacacacaaacact13240 ggtctagacctctgcctgtacttctccgctccggtattagcaggaaggaagaacgtgatt13300 ttgagaggggaatctttgcaaaaatcttgcgctagagcgtcaacatgactaaaggccaga13360 acataaatttcaggctgcagggcttggccgagtagaaggtgcagggagcatactactgga13420 tacccatccgtagcatacaacacgcgaatctcttcgtacgaaacatcctcactaggggga13480 gcgccgcagggttcacaatatccagcttgggaagtctctgtctcatttagcatttcgacg13540 agcatccagtcatctgcctcatactcccatttggcgtctgggacacagtcgaagttcatg13600 atagcaaggaaatgtggcagctactgaagagcgtgttctgcggccggtctaactcagaga13660 gtaaatacgaagcccttccaactgggcggtgcctgcccgtagatgatcgaaaagtacagt13720 cggctgtgaagcttattaaaatctttatccctaactgcttggacgtcgaagatgtcatcg13780 gctcgagggatgaacttaacaaactcgctcaagccaggcaaattagccgcattctggcaa13840 aatcggccgcggctatgcagattgctaagaatatgagatgcccgcgaggagcagaggcgg13900 ttttgcggcaaacgattgtggacaatgggacggtatttcgttctctgtactctgtactag13960 cctacctatatctctcccctggggcagacacggatggactacttgcacaagtaaccgctc14020 aaaccgcagacaggacgatgatgctaggtgacatgaccgtgcttacacatgcaatgcacg14080 tagacggaatggatcgtgaccatagctctttggaactactgcgcatgggtctggtaccaa14140 attcagacctgaaagatccaatcgagctcgtgccggtaattgataaactgcctgacaagg14200 tactgttccctgatcccgtaccgacactgccagttgaaaacccacccatggagcgtacta14260 gacctgcaaagacacgtaaagaactggttgctgcgagttaagtgacttctcagcgcttta14320 ataaagtatgtttaaattttccaatgtcagtacattatttgccggtagatccaaa14375 LeuPheAlaGlyArgSerLys 750 ccccccgtcaccccgaaccgacaacgtattgcgttcgtctactactga14423 ProProValThrProAsnArgGlnArgIleAlaPheValTyrTyr 755760765 gtttactattttccagcgaagggcatctggctctccgagaaaggtgct14471 ValTyrTyrPheProAlaLysGlyIleTrpLeuSerGluLysGlyAla 770775780 tctcttctcagtaactattagctgtgccactcggtcacctgcgtgaat14519 SerLeuLeuSerAsnTyrLeuCysHisSerValThrCysValAsn 785790795 actggccgcttcatctcgaatgttagttagcgaaaatgatatccaatc14567 ThrGlyArgPheIleSerAsnValSerArgLysTyrProIle 800805810 attatcctgcacatgtatcgggtcgactaacagtcctttcagattcat14615 IleIleLeuHisMetTyrArgValAspGlnSerPheGlnIleHis 815820825 ggaggatctccctagtatgaatgcgcgccagaaaggtccgcatgctag14663 GlyGlySerProTyrGluCysAlaProGluArgSerAlaCys 830835840 tttttggggaagggtaatacgggtagacgactttggaagaattgttac14711 PheLeuGlyLysGlyAsnThrGlyArgArgLeuTrpLysAsnCysTyr 845850855 atctttagtagctctaatatcatagcctccatctcctggacgtttggg14759 IlePheSerSerSerAsnIleIleAlaSerIleSerTrpThrPheGly 860865870 ggcaaagatttcgttaaacggaaacagtgcggcagggcaatctggatc14807 GlyLysAspPheValLysArgLysGlnCysGlyArgAlaIleTrpIle 875880885890 tgatcgcagctcgactgtctgatctttaacgagcgatcgtgtagctcc14855 SerGlnLeuAspCysLeuIlePheAsnGluArgSerCysSerSer 895900905 gacgatgatatggtgtcgcacctgggctacaaacttgatgttcgatgc14903 AspAspAspMetValSerHisLeuGlyTyrLysLeuAspValArgCys 910915920 gccacaaaaacgattgatattttctggcgtcgctccattcagtataac14951 AlaThrLysThrIleAspIlePheTrpArgArgSerIleGlnTyrAsn 925930935 gatgcgttcattgcaggctgcatcttgctcctgcaattcttcgaatgt14999 AspAlaPheIleAlaGlyCysIleLeuLeuLeuGlnPhePheGluCys 940945950 tcttctgtaaaacgttgtacatcccatacaaccaatgttgcccggaat15047 SerSerValLysArgCysThrSerHisThrThrAsnValAlaArgAsn 955960965 agttattttcgcccttaatatatctggaggtatacttaaaagggaact15095 SerTyrPheArgProTyrIleTrpArgTyrThrLysGlyThr 970975980 tatacatttctcgaaaccttcacccaaataatcatcttcgccttggaa15143 TyrThrPheLeuGluThrPheThrGlnIleIleIlePheAlaLeuGlu 985990995 agaatctgcggtttctaagagtaggcgcgcgtatcccgtcccaca15188 ArgIleCysGlyPheGluAlaArgValSerArgProThr 100010051010 cttgctaagcatggaatcgttagccaactttataacatttagccg15233 LeuAlaLysHisGlyIleValSerGlnLeuTyrAsnIlePro 101510201025 agcccttacagtgcctggtggaaatataacatttccgtctcttgt15278 SerProTyrSerAlaTrpTrpLysTyrAsnIleSerValSerCys 103010351040 ctctgtgccagtcaaaacattcccgccatcgtttacaagtactac15323 LeuCysAlaSerGlnAsnIleProAlaIleValTyrLysTyrTyr 104510501055 cagtattcccaataatcctgtatagtctgcatctaccaatcctgg15368 GlnTyrSerGlnSerCysIleValCysIleTyrGlnSerTrp 106010651070 aataatttgataacatgcagcatggccttccacatcactgataac15413 AsnAsnLeuIleThrCysSerMetAlaPheHisIleThrAspAsn 107510801085 gattccatacccgactggcaaagaagtcctaatcgcagaatcaat15458 AspSerIleProAspTrpGlnArgSerProAsnArgArgIleAsn 109010951100 tcttaggacgggagagtcggtgcgtgttttcgctattgttgcttc15503 SerAspGlyArgValGlyAlaCysPheArgTyrCysCysPhe 11051110 aacgtttgtaatgacacattgcaaggaatcgaggccaaaaatgtc15548 AsnValCysAsnAspThrLeuGlnGlyIleGluAlaLysAsnVal 111511201125 ccacccagatccaatctctattaatgcatttttttccgttgtcat15593 ProProArgSerAsnLeuTyrCysIlePhePheArgCysHis 113011351140 ttccatctccatgcaagttgcttagacgccaaaataacaccgaccctttcag15645 PheHisLeuHis 1145 gaaatccgcgtagttaaaatcggcagtagaccggtaggatacaaatagtaccgcactgcg15705 cgacttagaggacccgtgaaagagactgcagggcgagctctcgcaaaagagcaatgaggc15765 tgccgtgggaaaggagttttatgctgttgggagcagtggtgtatttgctgcatttggcac15825 tagtattcgcgcaaccgggtgtgacaccaggacacggaatggagcatgggtattatggtc15885 ttggcgctggaaatatgcttggagcggaaaattcgatgtatagcgcgaacatggaacact15945 tttaccacagtgcctgctcgtcgcgcggattttccttagtaaacggaacagctgcttccg16005 ttttctttttcattagcctggcagtggcgttgattggcctgctggccgtgctatataacg16065 gttgtttcaacagctttaaaagcagtgtcattagttctcgatggtagcgcagtatctgct16125 gtaaagacgaaaacatcggtggtgggaccatattagctcgaacactatgtcttactacaa16185 agatctctcggaggaggcgaagaagtatcacgacgatactcgacggaggcgagataccac16245 cacccgccgccccaaaccaccccaattcgaacacccctggtctgggcgaagaacatctcc16305 atatctagatttggatagaggaagcgattctgattcttcagaaggggattacggccatcc16365 atcgcgcgctcactattcgagagatcatacggcaccgcctcaaggccgccgaagcccccc16425 gatggaaagttttcgcaaagaaaccactccaaaggaggagccccctcaaagtaaaagggg16485 ctggaatcctgataatcattgcgctggcctgatgcgacgtttaactatctctaagggatt16545 tggtcctagtgctacaccctcaggggatgaagacccatggcatacttctactattccagc16605 aaatcgttcggccttcgtgcaagccgtctctgtgacggcaatggcccaggcagaattggc16665 agcgagagaggtgtgggacgtaacaaaaccacgcacgaatagggagttgagggatatggt16725 gagagagctagaaatcactataattatcaatccgggtgaatctttatggtctgttgccac16785 ttcggtggcaagagcaatcaaagaaggaaccccaataacccacgagctattgcagaaaag16845 accatcaaagcctccaacccgccgcaaaactgaagatggagccagaaagagttcttcaag16905 gccttctcaacccaagcctgagcatttcccccctccaagaagaaagacatccgaacgaaa16965 gtactagtttcgagagtctttgcattactgtgttcctcgccatatttgtaacaataaagt17025 atacttatgattggtaacatgcgtgtattgtcatgtgttcatagactataaaagcgccgt17085 gatttacatttctgcgcacactgcgcagaaccatggaagaagaatcttccactggagcct17145 ttgcactgtatgaagtcgaagacttcatcgaggaagtagaatctggggctggggggaggt17205 gcagcgattttgaggatgatgcgactgacctaattgaattagaagatctctattttgatt17265 ggttacggaatccaggtccccccgcgctggtcaatgcgccaaagtacgttaggccttcaa17325 aatgttcagcatcgtttctcgcaaaaaacgcgctaacggagctgcaatttgccgactggg17385 acaaaatacagcacgtgttgaagacgataaacattgatattttctcgtgtgtaccagtgg17445 gagaaaatggtctatgcaatatggattggttttccctcgatacagaaaaaatatggacgt17505 taatggattcaggaacacctaatgttagcccaaatttgctgataacacctggcccgccac17565 ccgaatgcattaaaactccagaagaagctccagcttattttgaagcaatctcgaattact17625 ttgaatccgtgttagccgccagagaagccgaatatgcaaaattactggcggagtacgcga17685 agtcgctcgctaaatacatcagacataaatcacaaaaagtagggcgcggtctgcgagccc17745 tcgaactggacacagaggaggccaaaaaacgatttaccgttctaatgaaatccgaatact17805 acaaagggatcgaaaaacttctaattatatttctggttcatttagtgcttaacgcgtgta17865 gggatgttgctcggataatatgggtccaacagagggactcctcgtctgtattgcagaagg17925 taacgtataggtgggaaagccaacagctacactgtatttttcaaccattacttgtttctc17985 cgggtccagtttttttggacaacgaccccttgcctttacagactttgcagcatgtaaact18045 acgtacgatatcttttaggagttccggtgctaagattctccatgatagaagaatccccca18105 gtgcacaatatatcccttatgacaaaactgcaccttctgcatatgatgttttagcgacta18165 ttgcacgtacttgcctaacttccagcggctgttcgcgtgcttctcacgaccatacctacg18225 cacgcgataacgaaaaaccaaactactcctcctctcgaatcgtcttattagctgattccg18285 cccttgatacacctatgccctaaacatgaccgcccaggctataaaacagatggactggcc18345 agacaacatcattgcagcgatggctgaaggcgatgggtttgaagagcgtctccgcgctaa18405 agcgcggtgccatcagatgaagaggactccgattggactcctccaagtaatccttgacgg18465 ggcaaggaaaattgatccgaaacggattttagataattcttccccgagcgacttagctgt18525 gttagctgagcgagagctaccatcctccctgctaggaccggcgcgcgaagaatacttaaa18585 atttggggataaaaaactgccagacaactttatctcacgcactgtctccaatgacaccac18645 ggatgagtatagaagaaatcttgacgaagcgtttaaactctttattgcacgcagaggggt18705 cactgaaaaatgcgttgcccgaatgctcagacatctctatgccaagcggttgtccgtggt18765 tttggatctcgatgtcccatttggtgaaaaaataaacaaagcgctttccgccgatgatca18825 agattttgtactgaaactgtactactgggttttcccggacaaggtctctgcgcctagact18885 taaggaaccagaaatgcaagcttacctggcttcagtaacctatttgtcgtgcacctttaa18945 gttcattgaaggatacgcttattatatgcgcccccctgggccagaactccattcaacaga19005 aacgaccgctcgtctagcagccctccttgtatatgtgagaagcatgtactgcaaactggc19065 gtccttatttgacgcaatcgatgccgctgtgctgcgctctaaatttaataggggagcttc19125 ggctcaagctctgactggaatttatggatacacgcgaaacgggaagggaactataatgtc19185 gcggtattcttcggaggccatgagtgatgaaatcatgtctgtgtgtcgcactggttcgga19245 cactttgatagaatctttacgcaaagctctggggagattgaccgaccttattgctaggtg19305 ggagctcatttcggtagagaagaaaagggacgcaaaagaggccgtgacggcagcgttagc19365 attaagtggactagttagcggacatttgggatacttgctaaacctaatctcaatggcata19425 cgttttttggctccctgggcattatttaaatatgcggttaatattggcgctgagttccag19485 ggaactcctaagccatcttttggctacaaatccttcttcattgagggaagtagccagctg19545 cccgaaaatacttttctaccaatctgtagaagaatggagaggacaggaaagaggaacaca19605 gatttggttggattatgttactgtaagggcatggttggattatatcgacactgggatccc19665 tactattcgctccgaggaaacaaatgcttccataaatgaaatttccgagtatctggaaca19725 gcgacgctcggccagtcctactgaatcctttttatcttcagatggaccaccaaactcaag19785 cgcagcatccctgccccctacacaaggctcaatgcaaacacaaaacaggagacgcgaacg19845 acgcagtaacagtgtcgttatccgaaagccctcccgctctgcgcattcaaagagtaatac19905 cattcccgtgtttcaggaaacgaccatttcttattcggcaccgaattccccggcggatca19965 ttacgtagtaatgaattaagcctgtataactgtacagtaaatgcatcgccaatttttata20025 tttacgctctgaataaataatgacattacattgacgtaagatgtacataattcgtattta20085 tttactttcctcgtagactccgaaagacagggcaactctcaatgccttaatataccgcaa20145 ggcaggcgaaatagcaggggacatgtagcatattactccggcggttccagaacattgtag20205 attctcgactagggccacggacattttttgcgtgcttagagatgcggtggagtcatcatg20265 tatagaatttatgaagtaaacgttggcgcatttgccgccatcatccgcccaccatagtcc20325 ttgaggtgaagtgctcccggaccaataaaataaccggtctaaaatagtgaggaagccgat20385 tgcttttgaagatgaggcaattttccccccgagggcacggcaagaaagtttagcattttc20445 atacgtgtcttgaggcggaccacccccggcccgataacatgaatccagatgttgaatcca20505 gtcaggcggacacaatccgccttcccaggtgctgttcggcagtgcaaatgccatgacagt20565 gcttattacaaacataaaaatcagtaatcctaggaaaatgccaagcaggattagaagaat20625 cactttacacgccttccaatattgtccgcctgtattttcggggcgcattgaatgaagctc20685 tccggaaggatggggggaataggtacttgtcgtagaggatgaagtagaggaacaaacgct20745 tggctcatcttccaaaatagccctgacttcgaagggaagttctgccatcattttttccaa20805 atggcttcgttgatcttcagatggggtttgtgaaattataggggggttcaggtagcttcg20865 ctgatcttcagatgagggctgcaaaattactggaagggactggcctgctgctatttcagg20925 catatctagaaaatccacttgggccgctagacgaagcgagtaacgagggcgctgcacgct20985 cgaattttaaaaagaacaaatgtcatttctgcgtatagtttcggccccgttatggcgtta21045 acgtcaatatttcacgtattatgttattgaaagtggtgtcaaggtcatcacatggtgacg21105 ctattgcttaattgcgcgaaaaatgtgcgggcgcgagaaactggttcatagcactcggtg21165 cgaacgttacgtatgcagttaccgcccatatcatgtaaatcaggtcacgggactggattc21225 gtaacctatgattggtgcggggaggtctagaacaaacattcgcacctcagtattaaaaat21285 ataatatagatatactatatttttaatactgaggtgcgaatgtttgttctagacctcccc21345 gcaccaatcataggttacgaatccagtcccgtgacctgatttacatgatatgggcggtaa21405 ctgcatacgtaacgttcgcaccgcgatttcgagtaaccgggagcataaataccgcgtgcg21465 tttggcactccgtgcgcaatatgcgcccgccactgccgacgtcagatgctgttctgatcg21525 aaaggttacaggcgccggaattctgtacaacctaacgtagggcagggttccggcgccata21585 cgggtcgcaagaaacaggtacaatcccctttcccctaattcattatgtcaatatttttta21645 ggttgtggggcggcacatccggcaggatgtcaatcgagatttttgaatacaggtgatgga21705 gggagtaaccgacacggtgctggttttgacggagcgcgacaggctcgccctattcggacc21765 cattctgtttcgaggagggggacttacggcagcccggtgggctgtttcagtagatgctgt21825 tctaccgtggaccgaaaaaaccatccccccgttaaaggggtccaagctcatcattgctgg21885 ggaaccttacttggggttaacatcatctgatgttctctccaagtgtgaagggaaaacatt21945 ttttgtgctcatcgctgttccagcagccctcggacgctggatttgcgcgcccccgccacc22005 gcttctagagtccgttgcagaaaatgtgcgttgtaaaatttcagcaaccctatccaaaga22065 gcatggagcgcccttttgcactgccgtatacattttggggtcaactacacaggttccccc22125 tggctctagcttaggttggtcttgtgtcgggcaacctgtccttcgggcccctttaaaaga22185 agctaccaagcccgacgaatcgttacaatctgcagagtgtgtatttaagtgtccgctttt22245 tgcggatgagttttcggggaataacccgtttgcaattgggtttttgtgcgcactggacaa22305 gggagttttgaagcacgaattgtttgcagcaatttatgcagcaaaaaaggcaatttcgaa22365 tgcatccttagacgggacattttgtgcttcgtttggagataaagagatgaaattagaaag22425 tgtaagcacccacttagggcctgccgttgtggtaacgcgtggggcaattacagacttccc22485 tccaaagaacgaatttatggatcggcttacatgcaagcgaacctttttgcgtaaagatgg22545 ggactttctcctgggatctgcgttcttaatgtgtaagcgacaaaatagaacgtcgccggt22605 tttacgcaggtggaaaagggcctggcttcgagataggcgaaggaaacatttaatgcgcag22665 ggcaagggtttcggtaacagctgagctgggttgtcggattttatcgcatccaagcagaat22725 agcatccttcgggctagaagttacagaaagagatctgaatttacagcggaggctttcggc22785 acatagaccgagggcccggggggtggtatatgaagattttgattagttacctgaagagac22845 acgccccaaaatcccacccacgctgatgcatgccttgggcataaaatactct22897 MetHisAlaLeuGlyIleLysTyrSer 11501155 gcgatcttcgcagtggtcaggcatactttatacgctccaacttca22942 AlaIlePheAlaValValArgHisThrLeuTyrAlaProThrSer 116011651170 gttgtcatggaacagcggcgagacgaaaaagaagcggaggaacag22987 ValValMetGluGlnArgArgAspGluLysGluAlaGluGluGln 117511801185 aaagtatctgcaatagccagtgcctttctcaatgtgggacaattt23032 LysValSerAlaIleAlaSerAlaPheLeuAsnValGlyGlnPhe 119011951200 ttttctcgtgggcaaacgaacaagtctcgaccgtgggtcacatca23077 PheSerArgGlyGlnThrAsnLysSerArgProTrpValThrSer 120512101215 tctgaaacaataaaagtttctatatatgcatggactcggtgcaga23122 SerGluThrIleLysValSerIleTyrAlaTrpThrArgCysArg 122012251230 gactctctactattttcagattacttgtttcgccgcggcaccatg23167 AspSerLeuLeuPheSerAspTyrLeuPheArgArgGlyThrMet 123512401245 gatagtgcccggcagcagttgcaggttggagtgcctaagaagggc23212 AspSerAlaArgGlnGlnLeuGlnValGlyValProLysLysGly 125012551260 ggggtgtacagacagctatcacgtgatgatggaacggtgttcgag23257 GlyValTyrArgGlnLeuSerArgAspAspGlyThrValPheGlu 126512701275 gtcagtttggatcctgcagtgtgcttcgagttctcagtgacgtta23302 ValSerLeuAspProAlaValCysPheGluPheSerValThrLeu 128012851290 attttaccgggacatgatcttttctggccggtagtgccgccgctg23347 IleLeuProGlyHisAspLeuPheTrpProValValProProLeu 129513001305 caatttctcgagctgataagtcagcgcgcggttattctggcagac23392 GlnPheLeuGluLeuIleSerGlnArgAlaValIleLeuAlaAsp 131013151320 cagtttatttcgtcctctatcatgaagcgagtgagcttatctcca23437 GlnPheIleSerSerSerIleMetLysArgValSerLeuSerPro 132513301335 atcatgctatttccgaagaatacattcatgcccgggtactggtcc23482 IleMetLeuPheProLysAsnThrPheMetProGlyTyrTrpSer 134013451350 ccggatccccagcctggtcggtaccgaccaaaatttcagcctact23527 ProAspProGlnProGlyArgTyrArgProLysPheGlnProThr 135513601365 cgatcagaacaacatttcatgaccgtcggcaagctggtgccaccg23572 ArgSerGluGlnHisPheMetThrValGlyLysLeuValProPro 137013751380 tttcaaattgacttgcatgggaaaaagaataatttcatggctgga23617 PheGlnIleAspLeuHisGlyLysLysAsnAsnPheMetAlaGly 138513901395 attgccgtgggttttcacggcccgccgaccttgacgggcactatt23662 IleAlaValGlyPheHisGlyProProThrLeuThrGlyThrIle 140014051410 cgcgccctgactgaacaagcaattcacaacgctgtggccgaggtg23707 ArgAlaLeuThrGluGlnAlaIleHisAsnAlaValAlaGluVal 141514201425 gttcgaacgcttgaaccgatgactgtggttccgatcactctgaaa23752 ValArgThrLeuGluProMetThrValValProIleThrLeuLys 143014351440 aatggaactggagctctgatgggattgacttcagacaacaagggt23797 AsnGlyThrGlyAlaLeuMetGlyLeuThrSerAspAsnLysGly 144514501455 cttcggatattgataaaaccggcactaggagaattggccaggtct23842 LeuArgIleLeuIleLysProAlaLeuGlyGluLeuAlaArgSer 146014651470 ccacgaagacggcgttccgaatcgcgcggaagagagtctgtttta23887 ProArgArgArgArgSerGluSerArgGlyArgGluSerValLeu 147514801485 ttataaattgaataaacgcagactttttattactgtcaataatttatttattggtc23943 Leu tttattacacggctccttcgggtaacattatacacgactcgattgcctctctggcaacca24003 ctaccgcgttctgcatagtagggatacacagttcttgttattgcggcaaaacgaccaaaa24063 tgcctggcaaaaaactgcaaaacctgtacggggaatctattacttgcgccccggccgttg24123 taaaatctggcgttggtccactttctgacaacatggcggcggcgtaaaaactcacgtttc24183 caagaatcgaataggacctgtcccatctcaagtttgcgtaggttgctgcggagagcgcat24243 cggggagagacagggattccgcacgcgtgaaggttttaggccataatctcagatatggga24303 cgaagtattgctctccgagaaactcttctgggaaggcgattggggcgtcaaatattccaa24363 tgcgtactcttcgcgttagacatgttccggaaaaatatatcggaatgtcaagagatattg24423 gggaagatgctcccttgcagcgcttttcgtataaaaagcgcgggcccaatatttccacta24483 atattgcctgtagtgctggtgcaaataaagggtcgcctgtgtgatcaaaagccgattgaa24543 tcccctgtatctcatcactggtcttgccaaagagttccggtagatgctcaggcagtatgc24603 tgatgtgatgataagatctgttagaaaatatccaacaagggccctgagcactaggagtag24663 gcctttgctgtcgtatagagtttccgtgtcgttccttgtctaccatactgtcgagaagct24723 ggttcgttatttcagcattttcttgtggttcatcatcttttttacgccggagtgtttggc24783 gtatccagccactccgaccggagtgggagttcttaactgaaggtaatgatggcgcgggtt24843 tcagcggaggggaaatcggcccagatatttccagtcggtgtagctgaggttccgatcgag24903 agaagcgcttgcggcgtccaaacggcatgaatttgctcagccagcccatggtgtctcgcc24963 tagagagttctgagtttcagagcaggctctcgcctagagagttctgagattcagagcaga25023 ccctcgaacgcgttcgagggcttttaggtgcttgttgcatggggcgtgtactgggcgtgg25083 atataagacatgtgcctcgacgcccgccacgcacgatttccgcagacatgagttccatgg25143 cctgctctcgttttcagaaaccaaaagcgaagaatgatagttcgcccgaaaaatgtgaac25203 gcactgccaagcaaattgtcgcagcaagtgattattgcaatgattcggaaaaattagagg25263 aagagatggtcttcgtcggagctggaaagatttcatattcttcgtggatgtacgaggcaa25323 ttttttcctgtgattgtattcccgacggatcagcgtttgcagttgctaagcatgcagtga25383 tcctaaatcgcgtaaacggaggcttgccatcttgtcttgggagtgcacatgggttgacca25443 tttaccctgccaggacaagccagcgtggaaggttcagccgtttagcatacagaaatgata25503 tgtccccagctccacaatcagaaaatactgtcgatgtggatggagagcttggagcgtgcg25563 ccatcggcgtgttggagatgggcgaagaagtgtgggcacatgaagaaatgttttttttac25623 cggtggttcctaagttagatcgcatgtggccgtgtgttcccaatcctgctctgttttggg25683 gcctggcgcgcgcgcttaacaatcttccccccaagatactcgtttcaggaaaacttgcca25743 aagggttcatttgccctctatactatcttagcgtaccaacttttggagaagagagcaaag25803 aaactttccttcgcacgagacagaagcagcgaagtctatatgaccctttgtttgaccctg25863 cttcattacttgttcagccacaattttttggatgtgatggtattaaggattctaataact25923 ttcaagctgggcttggcatagttttccagcctcaggatggatggacggcaaaaacaaagc25983 tgctcgagttggacagagttcggtcggaacttgtcacactatttgcacgccaggagcagt26043 caaggcctattaccgtgataattactaggggggcagtcagacgccggcttgtgttttcta26103 ctgttggagggtttaggttttcatcctcgttcgaaccctctgggacaccccttaaaaccc26163 actcggtgactttacatatttaatggaacacacatacgaaataaaagtttgtcagaaatg26223 tatttgcgtttattgatgtttatgtttcgggtaattatccaaacagatcaggccgcgtcg26283 caattcccatgttcttccatgcttcggacactgctgtgcaagcagccgtcttaaaatcgc26343 ctatctcatcgggggtccaatgagagtgcaataaaatgccgagtctaggtggatcgtacg26403 cgtggcaaattgctgcgcacagaaacttgccgcacatgggagtttcttctaaaagagcgc26463 gccagaaggtaaagcctcgcccagtaagccagctagtagctcttgatgcccatgtatcta26523 ccgctagatatgagcgttcgtccgatgccaatacccccgaaactgggaaaaacgcgcaaa26583 gaatgtgagttcctttcggaatcgaggctgtctgctgtgcgcgcggtggatgtatttggc26643 tgtcgccaatcgcaacacaaaacgggatacggaaagcccattcttcgcggcaagtaatta26703 tcggcgaagctatctgtgatcgatacgcgcgtaacccagtaaatatcgccgcttgtagta26763 gtccgacgggcgagtgatgcgggctgtctccgtgctttaaatcaaggatttctccgctta26823 gagtaagtgatggaggactttgaaagaacaaggccccgctgaatgcgcgtacagcagcaa26883 caaccggagaaagttccaaatccgagataagtcctaacattagaaatccgactccatctt26943 tccacttgtctgcagacaacagtttaaaaggcaaatacttggctccaaaagtcatcgggt27003 tttttgaatgcacgctatcagctacggcttgccatctttggaaattttttaaggaagctc27063 ttttcatggcaagaaggagctgctcgacgccaatctctaaattagaattagttgtgtagg27123 gagttctagtcatgataattgcagtagaaggaattccagtgtcgttggaaagggattctt27183 gcggatcctcaaataatggtgctgctacgaatcggatttgagagttatcgggctgttttg27243 agtcatggtcttgaaacacatgaatagtcaaatccttgttgcaatccagaaaaaacgatg27303 ctgtgccgtgcagtacagctaggccatattctaccttttctgtccatagttttccacgat27363 gtgttcctaattccatgtgagacgagtctacaaagtttgcgaggcagtgagttactgcaa27423 aacgacattcgcgattgctggtagacagtgctttggaagcctgagactgcttctttgacg27483 gagccatagccagttattcgtgctgccgcaagtgcagttgaaaagggtttgtaaggaaca27543 aggattaaagttcgctctcctcgtcagacggtagccgtacacgtctaaattgcgttgccg27603 agctgaggcagaatttatatatagccctgatggcactccatagagcaaccaatccaacaa27663 gtgcccctaccacaataccgataatgtatgccttgtcaaaaactattatgcttctgtcaa27723 gtcctaaaattcggacagcagttccgtgtggtcctagaagcgcgtagttatagaactcgg27783 ggttcatagacttaaaaaatgcaatagatgagttggcaccggctaacagttctgattgaa27843 catatgcactgtctataaagaaagcatcctggaacccccgtagaccgtattgaactatca27903 ggtggttgcaatatatgcaagttttcgctcgtccattcaaatgaccatcctccatttttg27963 ctgttcgcgcgatttgcggtagggagttgcaacttgaattcacaaacgttacaaacaaag28023 gggcagctgttgaggtatccggaagtctgtaggtcattccagtgctcggcgggctacttg28083 tcatcacccaactagaatgcgcggtaacagggaggaaaaatacgatgtggtgttccaggt28143 cccagtttaaacatttctttacctctggaaaaaacgcagttgccaggatctgaggggtca28203 acagagcttgtggcggtatcggtgcactatatgatggcaattcaccttcagatgataaat28263 atattttggtgtaaaaaaatcgaaatggagcagatgctgtcagaattattttccatggtg28323 cacttctggaaatatcaaaccttgtcgcaattgcacaaggagaaaaccactcttcaattt28383 tcgatgcctgtcctttcttgaagctcccgtctggttgggagtgaatctcgttgatatcgg28443 ctagccggtcgacagagcataaaattgtcatgcgcctgaggaagttccttccatgttgta28503 tagaaagttgaggagcccgcaaaataatgtacgtagaaactgccaataactttctgtacg28563 cgggggtcattaccttttgtgtaatgatttctctgtaactgttatctattatttcaagag28623 ccagttggctgggggtcactccatcgatgctcgccaggaatgcattttggggatcttgtt28683 ctgcagtgataagcaccgcattcatgatagtaagaagcaggttatgattttttatcatgg28743 gttcccatggcctgtcgtgcataattttaagaatactggatgggatagaagtaagagcac28803 caccgacattctgaataaagcgaatattcgttgtatagtttactgaattcgcccccccaa28863 aacacactgcgacttggtctgcccatgtttgcgtttctgcaataaactcgacgatctccg28923 aatcagttacgtatgcatcgatcgtaaactttagaaatcgaaaccacgcggccataaacc28983 gtgctgcgaatcttacaaaaaaagactcgtctatggtattcgggcaacctgcgattgcga29043 ccttctgcaaagttaaaaagtgtcccgcggatatttgttcgtcgaagctggccagctcta29103 agaaatcttgagcagcggtcgttactgctgtaaacaaatttggccgataatttggtccag29163 ctgcgacgttgatgcgcacagttaacccctgatcttcagccttcagcatatagggccatg29223 acttcagggacgtttctttaaccttcgcgctggttggtgtaattatcatctctatttgag29283 gagaatgctgggtcgcgattataagggtcgccacattcagtccgatgttaatcttaagat29343 ctatgtcactagtaactgcgaggctaatatatcgtgtaaacacaaatggaaaaacagttt29403 gtaaaggatcactgtaaattacacgaatcggagcgatgatgctctcgcccctatgaactg29463 agttatttggtggaaagttgacgagtttcgcagatgtaagtgcattccccttgtatccta29523 ccaaaagtcgatgctcaagctttggatcgttgctgaattttcgtggttggatggtagcct29583 cgctagcagaaccccatctcgagtaagtataggctacgtacagttgtccaagcaaatcta29643 gagcgatcgataaattcctgttagcgcttccaggaggcccaaagattaagtttcgatcga29703 caaggcatagttgtgtgatgtggccgttttcgactgctgtcgctatcgcaatgaattctt29763 tcggaggggccaaattttcactggtggggggcacgaagacaatttttgcctttgccttgt29823 catcccctttagctctaagtaatatcgccagaatgaggaaaaatatttctctcgcgtgtc29883 ccatcggcgcgggttgctggtgaagccacgctctctcgagtaagaatgagtacaaagcaa29943 ggaaatgagtaaaggacatactcttattgtgaaggattatggatgcggaacattacgaac30003 ccatatcagcattgtagcgctctactgcgtcaattaagctcgcgatcgccgctcgtttgg30063 ttgtaagagaacttgccgtctcggcaaactctaaacatttcagtgcacatgcctccgggg30123 tgaggccatgtgctggtaagtaaaaaatgcacaagtttttcaataccgtcgcgagttttt30183 gaaccacaaatgaaagtacagtttttaatctttccccgtgaacattttgctgatcaaaag30243 ctaatattgcaaatagcgtctggtcgattgaaggattgatttctggaacagtagcagttt30303 ctaagcactctctcttgaattttaagagcgtggcacttgttaaggcttcttgctccttca30363 acaatgctggataagatgtacgttggaggtaggtggtagtattcatgaggcagatgtacg30423 agttacgtaatgcacacaaatacgtccagtcgaccgtttcccctgggcgccccctttgta30483 ttatacgccgtgcctgttcgcaaatatccaaatccattaaaacaatgttggagtgtgttg30543 gaatgtcaggaattcctgacaataaagttattaaatctccaaattcgagcgctccgctta30603 gatattgtgcaacagggaaacacaaacatgccgcgagtgggtgcctatctacgaggaata30663 agacatcatctggtccggatgcagctgcgctgtagcagcgttcagatcccaaataattat30723 aaatgacgtggttcattattcttagtggggcagcaatagtcatctgaacttccgctacgc30783 gacgagacgcctcccgacattcaagttttccggaagcctttagggtttgtatttcattaa30843 tttctttgatcatatccgctccgccaaaccattggcgccatgcttgcataggttccgcta30903 agtatagacggcaacctctccaatttggcatttgcatcaacgtctttgcagtgactgttt30963 taccgactccgaatggcccgtcgacgtaaagaagtacaacgcggcgaaagtcggagtcat31023 cgttctcgaactcggagcaaaactgcacaccaccggaagttttcacggcgccagctacgg31083 ccatctctgcgggctagactaaatgccggaatccgttgccataatcgcttttaccgagct31143 ctcgtcagatcactggaggaagtctttgaagggggtggagacggaaggctggcctatacg31203 ataattccccaatgcaaacctgccgggggcaaaattgtagtcatgtttgaagtgaaccta31263 gggttgcggaaacctgattgcatttgtttgctggagacacaacatgaaatgaaatgtatt31323 gtgattgaactgaaaacatgtcgtttttccaaatctttgatgactgaaagtaaattaaga31383 caaggatatactggcactctccaacttcgcgattctgcacgattgttggagaatctggct31443 gttcctggcactgagaaagtaaagattctttctctactggtatttgttgctcaacggggg31503 atgaacatcttggcggtaaaaacggttggggaaacggttataaatgtatcgtctgagctt31563 ttctttgtcactctagctaccagaagccagtatttaaagactttctgcgcgaaattagag31623 ccacgcgtgtcgcatgcgcgcagtaagtatcaacaagaaagtgcaaagaatgcggatcta31683 gcgtctcccgccccttcagccttacaaaccgtagctgcattgttttcgtcgcgcgtggga31743 aaagagtccgcaaccaaacccgcgagctattccacttctacggaggagtccaaaaacttg31803 tccgaaccatgtttcgacccagattcgaacctatgaatttaccaaaggacagcaacaagc31863 cgtctaccttgatggttttagccgatcgtttaaactttatctcctgcgcggaaggctcga31923 gtaaatatgcatctaagcttttcgaaggaactctaatagacgcagaaatcatgaccaatc31983 gtgcaaggattgaagatctggaaaggcggaacagggctgccaaggcagctttagagcaac32043 tggaaaatatgagcgctactgttcccgtacatgtctcatcggcattgcaaactattgaat32103 atcccctagagactgtaattgatgtcttggatgatttagcccagcgggccgtgcaggaga32163 aggacattgttgggtcttataaaacactagacatccgtgcgcctggcgaggatgtccctg32223 cgaacgtaatttggatagttaagaatggagaaccattaacttttaatacagattttcaag32283 tagattttctgacaacttcgtttgctattgctggcaatggccggctgggattcgggtctt32343 ggtttcgcgcgctacagactcagctcctagataacaataaagctatcgctagggttttga32403 atgtaatgggagacacgcgcatctcggggcggtttatgaaaacggctattcgagcgctgc32463 gatcggcgatggaaatttatgctgggactcgacaatatagcggattcgaggctactgttt32523 tatgcttactgcactactcgcggtctagacaatctgcttcaaacattagacatggtcttg32583 atgtttctatatttgaagatgcattaagacatgttccaacgtatttaaattatatgctgg32643 aagatattcgggccgagtggggctcagttacattttcatttgaccggtcaaaactccccg32703 taaactttttttccccaattgacggcagaaaatattcgaatggagtgttcgatcctcaca32763 tagtgtatcaattgctaaagcgtactgggaccctttccaccacagtacgagatataacga32823 aagaaactctgcttccaatagatccagattttgttcgttttgatgaccccattgctgctc32883 tctccatttcatttttcccttcgagacgaacgccgttaattcttcatgaagatgatccgc32943 ttgtgcgaacggttatagactcgatatctctgctcctagtcttgcaaaagctaatgttta33003 atagtaatgtctatacgagcacacatctcaatcgatttcagccatctgcgttctttgaat33063 tgccacttggaacccaatcggaacaggaggcagctaaatggcccgtcgcccctgggtcaa33123 gacctcaagccaccgcaagcacatttgatgacaatggacaagatatggccagtcgcgaca33183 acaacttgttctttttattcgagaaatatgttgtacctatgtatagatatgacaacagat33243 gtgaagttactggtttctttcctggtttagctgcactctgcataacggggcgcgttaaag33303 gaataccgacagcggtacggttgggggagtactattcctccctctgtaatctaattgagc33363 ttgatctcagaaaaacgtcacatgtgggtagcggggcagctgctgttttggcggtacacg33423 attcattgacaggtgacgttgaagagggagtgtccaggttacttgaggtatttgatgcaa33483 aaaagcatttgaaaggaatattgaggacattcaacgtggagtctgattctgacctgatct33543 attttatgtgtcttggatgcttgccacatcacgtgacatatggataatgcttagtatttt33603 cgcgatcgcgtctctgtttagacaataaaagggttatatctttctgatcagtccgtctgt33663 tttgtcagtgtgttgatactttgcgggtcgagtcggtctcgctatgtcggagaacgtcga33723 catcaaatatatcttcgttgccggctatttggtagtatatgaccaccaagaaagtgccgg33783 gcgagaatatgagcttactcgcgagcaaagcaaatcggctttaccagttttgcctggaac33843 aattccgataaacattgaccacgagtcatcctgcgtggtaggtacagtgctgacgatctt33903 agacctgccgagaggactgttttgtttgggtgtcgtgtcaactgctcttgcacctatttt33963 tttaagctacgtgcaagatgatgctctttttgcgaatgccgaagaggggatggttttgac34023 ggagacagagaaatttctctatcttctcagcaacattctaccttctctatcgctctcttc34083 aaggcggcttgaaaagaacgaagtgcccggaaaagatttttttgcacacgtggcgctctg34143 tgagttgggtagacgtgaaggcacggtagcaatttacggggccaccgcttcggaagctat34203 tggagcatttgatgatttgagcgcaccaattaaagaacagctgtatgaaatagctacacg34263 tgagaaatgtgcagaagtccctagagagttgtcgcgaccagaaattacgcgagtcctgat34323 gaagaaatttattcacggggcgtttttgatggataggggtacctgtttgaaaacgcgacg34383 cgagatggcagctgtttacaacccgaaatatttacaagcgaatgaggtaataaccatagg34443 gattaaggaacactccgaagagactcctgagaatgctattaaagaccgttcagtttctac34503 gcaaacggccccaagcttcgatataagcgagagtcagcaaccgtccgggcaaacacacgt34563 tccagccatggagtcggcgacatgctccggccagttcttgcaaacaaaaaacggagcttc34623 accgtccgcatctcgtgaagatatggtctatgtcccattcgagaagtatgcgagtcttct34683 tgcggcatcagcccgcagagataacgaccggagacccgtgtcgccatcacgagagttttc34743 ccgtaggtcgcgggactctactcacgaatgttcaccaggacgtgatatttggccgcgtgg34803 attcgaacgacaccctcgcctagaatcttttatgggtccggggatgaaccacacttacag34863 accggctctttacgaagacccaaatttctgcgggcgtttcccatatattccttatcaaag34923 ccccgcatctacttaccccgtgcatccaaattattatagttcgaacttcggccagtttcc34983 tggggctggaacgtatcctatacagtatccatcattacatgagcagactgttgtttcacg35043 cttagatgccttgatttcggctcttgagaaaaataataaacgggatagcgaatactcgga35103 gaataaccctcggaagagatccgctaggaccatttctgagaatgacccgtacttccctgg35163 ggaaatggttccagcaaaaaagataactacggagcagcagctatgtgaaaaaaaggaacc35223 cgttggtagcggaattaatgatattttacaaggaattctgacccttcaaaaagaggttgc35283 cggtcttaaatcagcttccaatgccgattcgtcttcagagagaaaagaggaactagaaaa35343 tagtaatcaagagtctgctcgggagacagtcgatgcttctatgccaaaacgactgaaaga35403 tgctcagacaaaattgaaaagaaagaaagaagcagccgcatttgcgcaaatgatggcaga35463 ctgagtcatgtgaatagtaatgtcattttattaaataaactgcatttaaacttattcgtc35523 ttcgctttcttctgcccacgaagggtattcgagcagggggtagtcatcttccttggttcg35583 gggttttctgcgaaataggtttctcatatttttagcaaaagcagaaaaccgcgctttctg35643 tcttcgagctttctgttcatccttgtgtagaagctcaaggcctttcagaactctggtggc35703 aagtatcctgtcgtcctcatcactatcctcctcaacctcctcctcatccttgtagtaacg35763 tctagagggtcgtggaggagttccggccgggggaactgcgcctgggaacagaacctgaac35823 tgggtttgatttcaggttcattacatatttgaacgccagcagtcctaaaataatgctcac35883 caccaccgctatcccaattccgagtgcggcgaacgggttagaaagaaatgaggcgatgcc35943 agatactgtagaaattactgctgccgcggctgtcatcactacagttcccaatgcctttcc36003 tacttctccaagagtgttgccaaaaaaatctgctattgctctaaagattgcatctcccct36063 atctccacgtattacagtgtcaatgtctctgaaccttttgttataaatattttgatatct36123 gaccacatcatcatagtttaaagtcccagtatctctgagttcctcgcgagtgtatacttc36183 gacgggcacaaagtccaaatcttctagtatagtggcgttcaagttgatgaatatgctcac36243 ttcttcgatctcggaagcatttacttgtctaacaaatgtatagtcttcgtaaagaaggta36303 gttttctcccaacagaaagtaccgtctgtgattgatcatgcatggttctatcaaattccg36363 cccttgtaaaatttcattatgttctccgagttggcctaatatgtcaagattgtggttttc36423 tgttgagttcgcagaaaactgtgactcaggggaggacgaatacctgaaaataagtactgg36483 tctggtatagcacatggttgggtcccctggcatgcgcatggaatcctgcatcctaatatt36543 ttcgattggaatttctatacattttgataccgctacgatgtctcccaatagcctggcgct36603 tacaggttgtccgaacaaagatgtcatcagtgagttcgggtttagtttcttcatctcatg36663 ccatacaatcagttggcggttctgaagctcacaccacgcttccaacaaatttccgataag36723 ctcgttaacatgggcttggattttgtcgtatgcaaattgtaacatggcaaatgttgcaga36783 actgtgggtagtaattctatcaccctgaggtccagactgcagcgacgccgtgcggcgacc36843 tgcggcttggcgacgctctctccctctcgggagatgattttgtctttgtgcctcttctag36903 gtacatttcagccaagccatggctcatgagtttctgaaatgcgatcagaaatccgccact36963 accgagatagtattcgatgtccccagaacggacatgagtcgaactatactttctggcaaa37023 gatgccatctatggcctccgaggctatggtaggaacgcattcagccaaatgaagcctgct37083 gatgttaaaaggttgttttccggacgagaacgtcatagtcgtatctttaagtgaaaagtg37143 gtaactgtttttgtacgaaacacgaactgcttccgggacttcaatccatttactgagagt37203 acatacagattccttttcttccattgcatcccagcctatagtgaattgttcatctgttag37263 aaagtttctttttttagggggtcttatttgtccggtttccaaatccctgacttgataatt37323 tgcgatttcgagaaatctatagtctctgtagacactgtgacgccttggtccggtcgtgtt37383 tttggtataaaaaggagaaatttctactgtatcacctgtcgccattccaaagtaatcata37443 cgggtatacagatctagcctgtagatattccacaacacagtcgaccgatgtagacgttcg37503 gtatcccagggtttgatgtcgcttagtaaagttagttgtatgaaacgccttggagacagt37563 tgatcttaacagtgatggaaccaggggcaattttttttctgcttcatcattgtcgtaagc37623 ttcaaaaaacatgaaatttttatgatacgttgctttggatgagcattctcccgatcgatc37683 aatcctgacaatttcatgatagtctattggaaccctggtcacgtactcatttgttatttg37743 gggtcttgagaataatgcccacgtagtaactgtggttatatgtttatagtatagagtcac37803 attaaagacgtacggggcaatgttttgcttgaagactacggcaattccttcagtcatgtt37863 agtcgaatcggcatgtcggtgacaatgtcgtggctgggcaagcctcgcaacactggcgcc37923 agttggagatgagcacgcaaaaattctgtttctaatctggggttctttcggtgcccccga37983 cccaatggcttcggagaaagagatttttccaacatccatgctggctgtatcacgagggtc38043 tattattccagcaattccgtgtgaatcttgagatagggtagatgggatcaggattgccac38103 gcacacgcagatcagcattttcaagctagccatgtcaatgttcacggcgatgtaggattg38163 catacaggaccgcgtataaatctttctctactatgatagtagacgctggacccagtttcc38223 cgcggtcatcgacgccccacactgcaactaatggatgttcctcttcaaatgttaaatata38283 gcccgttttccaaaatcgggccgtcgaggtcgaattcgacacaatctgctcgcagtaact38343 tagtgttaccgctgtggaaaattttctcgaaagccgttgtagcaaagagtgcctctctga38403 tatatccgcacgcggctctctgaatagcagttgaattagaaatgcccgcgaagttataga38463 atcggcgaaactcacttgtcatccaatcacatgatctgtgacgttttgtaaagttggcca38523 actcttctttcaaatgaggaagaagtcctacgttctctacagaaaagtatatagacgtgt38583 ttgggggttggggaaatctctccttgtgatgtttgaaaagggggccgcttaaaatttcaa38643 aaaaccgattggtgaggcgcggtaacatggtttggtcgatttggtatctggtgatggaag38703 agcgtatgtattgatgccaatcataagcacgcccatcattttgatcgatgcgtagaattt38763 tcgaatgtagagactcttcagcgcaaacaatatccagaaatgcgcgtcttgctagaaacg38823 cattctttagcgttacgtacattaccggaagagtttctccgtaaatattcacacgcatta38883 atttttctagctcggctcgctgaattttaatgcatcgatccaagtttgaaaatgatcgtg38943 cagaaagcttttcgacgtagttcttttgtctgacatcaagatctcgctctgcctttttta39003 gaagaacttctatcgaatcctcgtccctttcaatagttcctctgaggttagcagtcaggt39063 cgcttgtactagttccttctgtgacaggttgtgtctccttgtctgagccacgcagttttt39123 ccactaattcctccagtgcatctgtatctactttctctgggtttcttaatctgcgaaaca39183 atgggagggatagatggtggtcatagcaggctttgatcaaggcagctatttcggtatccg39243 gtgaagtggccagtactcctgtgatcagcgtatccactaaagaatgttgtggggatatta39303 actcagctcgcgcgaccctgtgaaaatgtgcatgcaccttttcaaacagtgttctttcta39363 gacggatgcattcctgttcaaagtcttcagctcttttgaacagttcgctcagatctttgt39423 ctaactgctttaacacagattgtgaagtagtagtttgtgactctactccgctgggggtcc39483 ttttacccgacgctagccagtattgtaattcacttagttgatagacgggccccggtggtt39543 ccgtaaacacatcatatttgtttaagattttggaagcttctgactctccaggggaacttg39603 ataaggtgcgtcctgcttcgacgtggttttcagcttcgatgcgagtctcgtttgaaagca39663 cattttttaatttttcgggatccacatcccttaaaaatggaagatggcgtttaaggtcat39723 ccgtagatacattgaccggaaactgtcttgtcaagtgatcacaaattttgtatccaaggc39783 gtcgataaattgtttctccctgattagcggttacactaagctcttctaaacacacataac39843 acggctgaccatgatcgtaagtatccggtgctgctacgagacttccccccgagctgagaa39903 ccaaaaactcatctattgtatttagagcttcaattgcgtttttacaagatacaacgcagt39963 gacagtagtttagttgcttcataaagttttctacatcgttgatcagaacgagttcctttg40023 aaataattgaactcattccatataattgtagctggacctccgcatgcaaaggacagatga40083 atcctttcccgtacccaagcgtagcttcaaaaaaacattttctatcctttaggacagaat40143 acttgtctatctcattacacaaagctgctatttcggagcacgctcttcgaagccagagcc40203 acacgcaatatgtctgaagggttaacctataatttacttgcatagagagctcattagaaa40263 ggagcgaatgaatgtacaatgccattagcgcgttgtgtttgattctcgaccgcagtcgct40323 tctgcaacaatatctctggatcgcagcgcttcaaaatatctatttgaaataacagcgtct40383 gtagctgacctgccagagccataaggcgtaactgtgtttcttcagccatattccccagta40443 agaatgaaacaaaatacgtacaaggactttcttatatttatttgtttattctgagcatgc40503 gcagttactgttaacagaacagaatatcagccgatagcgaaggtttttttgcacttggcg40563 cgccaagttcaatatcttcgctgatgtcgccagtgtttgtatcttcatcctcgtctgccc40623 agaccaacatctctcctgcattttccgggcatgtatctttcccctctagctcactgagca40683 tactttgtgcggtagccacggaccacccattctgacttccagaaatgtcctcatggagct40743 ctactaatatatctaccagatacttgtcgtcagtaattgccatccatgtttcggcagtaa40803 tgtctttcattccttctcccagaactctcagaacggctgtgtagatggaagtgggactac40863 ctcctgcatcaattaggcttctcacttgagaggcaatggtgttttcttgaaaccctgatg40923 ccacttgcccagatgacagaatagttcctacccttttacaagcaagtgcaaactttctga40983 cgggatcattcgtcagcgcggaattaaccgattgggaccctgaattgcctataaggctac41043 cccaattgccggactgaaagacggtggtcgagttttgttgtcctacatatttgctgatca41103 taatccctaacattactataggtttagaactcaataccacgcggcacgagtttgacgtac41163 tggatccgcttatgcagtagtcagagacttcttcgtgcctttcctctgactggtgtgcac41223 ctgtgtctccgagttgtgcgcgcgcgaaactctctttgccctcacttgttggctttatgg41283 aggtcgtaatgatcatcgatggagtacttatataatattgtgctctgtcggccatctctc41343 cgtggtcgcagaactccaacaccttgttggcgagcataaaatttgctagttcaagcaggg41403 tagttggggagcacttaataaagtttccctccccatagacctttgaagtttttcttataa41463 attccaaataggtaatgtgctctggagaaaggcgtcgtttgggcatattcccagtcaaga41523 tcaaattccagaatcgaaatgcgttcatgtctttgccgaaaagatttgcatggtcacgct41583 tgagtataaatcccaatggtccacccaaaatattgattgttttggtgcccggtttcaaaa41643 aggcatcagccattccttgcaatctgcctctgttgctacccgactcgctggatccgttga41703 acacgacgcggttcttcaccttaaactctttcagtttcaggacttgtcccctagaaagag41763 aatactcatattgtgcgattgcctgttctgtgtttgggcgcattgtatccggagcgttaa41823 cacacggaactgatattgaaaatggctcatattttccagaaaggaatcctttgtccagca41883 tcccgttaaaggctgatcttagggccggcatggcagaagaacggaacatttttgactctg41943 gttgccgcgtatcaaatgttccatggatttgactgagaatcaaatcttggaaaagtattg42003 agcgagtctgggcgcacaataagctaagtactggacagtacgcagaagaatacgggttca42063 gggtgattccaaatgtatgtacgattgaggataagtgctctttgtaatgatatgctctca42123 ctcctgagagggcagaaatgaacttagagcattctgatccaacgaagttctgaatttttt42183 caaatacagtttttaattctgctaggcttgaaatattatgcgtgtcttcgcccgtgtctt42243 tgtttatcaacccttctgatactagatattgaaagactcgccagcctatgcccctgtatg42303 tgtcattcataactgctttggctggttcaccgtcacctgccctctttaactgggaatacg42363 gggcaaaattccccaaaatgtcgcagtccgtgtagtctccatcaactgctcctatcactg42423 cgatagggcttcttctcatggttcgtggaataggaaaacgggttctcagtcgctgcatag42483 tgtaacggatgcaatgattcctagactcgtcattgcaccaccggcattctggtacggctc42543 cagtacaaggcgcttttccactgttagaaatcgaaatcagattcatgtttggccgagtgc42603 tgagttgcttggaacatttttccaaataaaatatgatacgggacaggagttcggggctaa42663 aaccacaggcatatgcgaggtgctcaggatcatattcgaatgtgttctgaggtgtgagtg42723 gagatggacatgtgccttcccaaactctcttccctgagtagtccacctgggggcatccca42783 ataaatgcaatccacatgtcagataaaaacgggttagtccgctcgaggcgcgctcgccgg42843 gctccggcgcacccccatcgactacctcacttgcataaaggggggagttatttgaaaaaa42903 ttgctgctcctacaatgccggccaattctgctgagaaccgatcgagagcttgaacgcgct42963 ccatttgagttttgcaatcgcagaacaacggccactcttcatacggcagaccgcagccat43023 tatcaaagggatatggagcgcaggagacagagagtctagttgccagcgcaagttcagcag43083 ccaagctacaggcggcgcgccgttctacttctacattttgtttagggggtcctgtttgtt43143 gtatgttctgagccagctcggtaaaggtcttgtccgaggttaatacacagccttcgaagc43203 ttccatcgaacgcgagcattgccgctccgcgcgccacggcttctaggtctctggttctca43263 gactttgtccctgtgttccgagtgttgtcccatgaatgagtctgttcaaagctttgttga43323 ataatggggtagggtaaatgcagccttcaccgatgttacggctgtttgaatcaaatgggt43383 tacggcaaagccgcagcgcgatgtctggcatgtacatttgcacagggtagattggtatgc43443 gcgtaacaagcttagaattgatgtaaagcgtctcgactgatccatagtgaatgtatgtgt43503 tgcatacatacaccgcctcacaaaacggttcggcaactacgagatagagcatcgttttgt43563 cagggtccatattcagggatttgcagatctcttctcctgtagtttcgatggcatttggaa43623 ccggtccatttgggggtagtgaactgaacccgaacctttcccttgcgtcctcgcatattt43683 ttgtgaggtttggagtgaatgatgtaggcgggatgcactctcctccatgaaagatatata43743 ccgttgttgaaaaatggcagggagataaaatagccgtacaattacctccaacgactcctg43803 atgacttagttccgatgactgctgcgacgtttggcttgaaatcagactctacagtaagcc43863 cccgtatgagaggagcgatggcgcaggagggctggtcttgacttttggcgcacagtatct43923 tccattcctttccatcaatctcttcgcggggtcttgcatatacgtagccaattggcccaa43983 tacaccatggtccgccatccgactttccgcccttagttgtgccagatgaactcttttcca44043 tttgcgcgagttatctcagacagtatgatctcagatcagagttccgcgtagtagagtagt44103 ctccgtcactgagcgcggacttaagtaccgcggaaaggacacacctatgtatactttaga44163 gagttcataaatatcgatgattgcagtagctgggcaccgagtttgtcactctgcactatg44223 gacactttttcctccgccggtactggagctgctcgtgtagccccgataattggcctcggg44283 ccgcactctggcgcgtcttattatacttctgtgagagaattcccgtatgtatgtccaacg44343 tgcattaatgggggcggaaggataggaacgcagattggaagggctacaagcaaaccaacc44403 ttttaccacaacgagcgacaattagacatcttgacaagcacacatggagcgtggcccgtc44463 aggatgaaatattggaatgctggtcctggaatgactcaccacaacaagggagatgtaaag44523 ttttatgaatttcacgtttatgacctttttgaaaacactgagatcgctcagtcatgtgta44583 cgatggatgcattccagatttcttgatacactgaaaccgaccggtactgtaataacctta44643 gttggaaattctgcatgcggaaagcgcgtcgccgttcatgtgtatggatctttgccatac44703 ttttttgttaaaaagcgagaaattgaccaagccgcgaaagtcacgaactcggaagagttg44763 gcgcatgctctagcattagcgacgcgtaagacatctttaaaaaattcaccttttctagct44823 gtttcagcggaaagtttttgcattgatgttgttcggcgcagagacatttattattttgaa44883 tctgaggaggaggacttctaccgtgtaaaagtgtgtaatggcaaagtgatgaaatttata44943 tgtgataattttttcccgagcgtacctaaatatgaaagcaatgttgacgctattaccagg45003 ttcatcctcgacaataatctgacttcttttgggtggtatcgctttagagctcaaggtggc45063 gcactccaaattcgagacccaggacaacatgctacatcagctgatgtcgaaattaactgc45123 acagcaagtaatttggaactcggaaacaatgtctcgtggccagactacaaattactgtgc45183 tttgatatagaatgtaaagccggaggggcaaatgagtttgcatttccttctgctgagaag45243 gtagaagatcttgttatccagatttcggcagttacatattctttgttaactaaggaaaaa45303 gagcaggaaatcattttttccctagggacctgtgaactttccgaagattgtagtgatggg45363 ataactgtatgcgaatgtggctctgagttcgagcttcttctgtgctttatgacttttttc45423 aagcaatattcacccgaatttgtgagcggatacaatattctagggttcgattgggcctat45483 ctttctaacaagctgagcaaggtgtatggcatgcgtctcgatggatatgggaaagcaaac45543 tcgtgggggacattcaaacttcaagatccgtctgcgcgcggacttggaagattcaaaaaa45603 gtcaaaatcaatggcgtcgtcaacattgatatgtttaccattagttatgaaaagctaaag45663 ttaccatcttataagttaaatgcagtagcagagtgcgttcttggagaacaaaaaattgat45723 ctggcttacaaagatatcccagtcatgtttgctgcaggccctaaagaaagggggaaaata45783 ggggagtattgtttgcaggattctagactgtcagggagtttgtttttcaaattctcccct45843 catttagaaatgtccgctgtcgctaaattggcctgtatacccttgacaagagcaataggc45903 gatggacagcagctgcgcgtttatacatgcttgctccaacgctctacggcgtccgggttt45963 gtgttgccggacaaaaagagtgcgttttccttcggttctactcttgcttcagacgcgtct46023 gatgcacctgctacaagaaatgtaggctaccagggagccaaggtactagatccagaaata46083 ggattccatgtaactcctgtggttgtattcgattttgccagtttgtatccgagtattatt46143 cagagtaacaatctatgttacagtacgttaacgcacgaccccgccgcactggcaggtcta46203 cagccagaaaaagatttcttccagattgatgttcagggtcggaaattttattttgtcagg46263 gagcatattcgcaaaagtttgctgtcagacttgctaggtgattggttatctatgaggaaa46323 gccgtgcgcgcaaaaatcaagacagccgagactgaagaagagcgaatcttattagacaaa46383 cagcaagctgccattaaagttgtctgtaactctgtatatgggtttactggggtgatgcat46443 ggaatgcttccttgtttagaagttgcttcaacagttacagctataggaagggacatgctt46503 ttgcgtacaaaggcgcacatcgagaaggagtggagaagtggaaatcagtttgccgaaaaa46563 tttttgcccgggtccgaacgtattcagctaaaccaatactctgtccgggtcatttatgga46623 gatactgattctgtatttgtgaagtttaccggagttgacattgaaactttaactcaagtt46683 ggtggctgcatggccgatgagattacacaagcgctttttagagctccggtaaaacttgag46743 tgcgaaaagattttcgtgcgcctgttactcattgctaagaaaaaatacattggggtgatg46803 catggaggtaaaatgttgatgaagggcgtagatctagtcaggaaaacaaactgtaaattt46863 gtcaataccacagcctcccgattagtgaatctacttttcgaagacgacgaaatagcgatg46923 gctgcagatacagcaagagccggatttgaggattttgactgtcttccgagcggacttact46983 aagcttggccggttgattgcagaggcaaggctagctattaccggcaacggactaaacatt47043 agggacttcataatgaccgcggaattaagtcgtgcggtggataactatgccagtttgaaa47103 ttgcctcatctcacggtttatcaaaagaaagctgctcggcgcgaagaattacctcaaatt47163 aaagaaagaatcgaatatgtcatcatagaaccgggacaatctgtcccgaatgatccagca47223 actgagtcttttcctgaactaaaagaaacttctttgatttctagcctggcagaagatcca47283 gaatgggtcgtatcaaatggtctaaaattgaatgtagaatactactttgattcgcttatt47343 agaacattaagtgtaacatttaacgcaattttcggtgatgcaaaaacagcagaggatgtt47403 ttaagaagctttattccagagaaaatacagttttctgagaaagttgcagaggctcttgca47463 cgaaacaccgcgacatttgtatccatcaagaagtaatcggagggctgtaagttgcaaatg47523 ttgaataaagtttagtgtattcgtgaattttttcgtctgttactaggatatcgcagtatc47583 gtcgatacactgactccgggttcagcttaacgcgctgatgctcagagtaacccggtccat47643 cttctttggaaacgatcaataagaacgtaccagcgaatacgtccacgtgccaagtgtatc47703 ctgggcaattaaatattaattgtttcagaagctttgcccctagatgaagtggcgtgctct47763 gtttaaatacaaaatacataaggtatcccgatggaaacttcttagatcttggatcgttca47823 ccaagagaacggtaaaatcttgagagagtccgccctttactgtatagtatgcataaaaca47883 aagtcgcctgggccagtagatttttgatagtgtcaagtaggaattcgttttcatatgctc47943 cagatccaactaccgattcacctgaaaatacccgcagggacgccactaactctttgaatt48003 cgaccacagagctcaggtgatggagaaaggccaattccaacgcaggcaagtctaacggtg48063 gggcatttgaccatccatatgagcaaagtgagcagcatccaccaggtccaacggtgtagc48123 ccatctcggaaagagagatacagtcgccaggggcaaaacttgcattcacattgtaaggaa48183 gggagatattttcttggcgtatgacaggaatcgtcattgttctaagaagggagatagtat48243 cttccggagatgaagccgttagcttgaaaaaagcatcgaagaaagttctccgtgtgtcta48303 gattagcccttgacctagacgatcgcctcttcgatctgaggtatgagatgtagcgatggc48363 gttcgatggcccccgtaatactttttcttcggatgcgcagagcagcggcgcgagaacgga48423 agtcagacatatcgagtcagtgcgtgttctaaagcaatgcagctgattccgtgcctcttt48483 aaataggtctcagcgccgcgaatgaaagaatttaaagcggtagggcgaggaggagaaagc48543 tggtaagctttaaatgtgaaggctagaatccacagcccgcggcaaacccgttcttgaaat48603 atgttagccgtggcgatttcggctttataaagctgcagcagttctgggtccttgggttgg48663 ccttcccacaaaacttttggatttacgcgaagcgtattaactgcacacaatggatcgcaa48723 aaaaagtgtttgtaaattgcgtttgccccggccatcctcaataaggttaacattcgcccc48783 ccatcgtttaacgcagtatagtcttcgaacgtttctaatgctggttcaatcccatcgaac48843 aagctgctatttacgttactgcagccgactactttacttttcagctttcgaagagcatgc48903 cagtgttcccgagtaagcatgagattgcacaacacgcattcccctccagtatctcctcgg48963 ctagtcgggtgaggcaaaatagacgccaaaattgggccaatggcaagtgatggtttggta49023 ttgtcgcaaatgtactgcttcgctgtcttggggagcctagtatttttgacctgttggatt49083 agcgttgcgtgaaagttctccactacggtatttcttgtccgaattataggggcaacgaaa49143 ttttctccattatcatttgtatcatcatactcaggctcgtcgctgcagctggcatcgagt49203 tcccgatttggcataccggctgttccagcaattaataatgccgtcaggtcggtaaatccc49263 catttacttggggttgtcagggtttcgcttggtcccccttccacatattttgactccgtg49323 ctaatatcttctaaagcagctttttgcgcacaggttcgaaaagcgaaggaggcagtctct49383 gtatttttcctctttaacatacactgcgcggagcaaaaacactcgagtggtctggcatac49443 tcacgccattttaacaaagccacggccattccgctacttttttggaagttgaaatctgca49503 gacgcgccagagaccggggcaatttttgccctaagtgcttcttgatatctagtagatagt49563 aacgcatagcgtgctaccgactgcactaggaacgaataattatttagatctattttagag49623 tccagtcccccttccaccgctttgaaacagccgttaaaaaagaagtgcttctgaatatcc49683 ccgagggaaaattcccgacggcttatagcgccaactaaagaggtgctgtgggaatgcaag49743 tagtgtttgtccatgatgaagatgaactcaaaagcagttatgaaggtagatgtagcacac49803 agggggatgctttgagatttgaagcacaataaagagtagtccaccatccattcgggagtc49863 acggggaattttttttgatatttggtaataatcttgcagacggcgcatgatttatctagg49923 gtgtataagtcagccatggtttctacgaaagaatcaatgtccggaattctgttttgttct49983 tcagcttgttctgtactttcttcatgatatatttcaattaggtgagctccatacaatagt50043 tcgtccgacaacttgtcattaaacgtcagaatcgccgggtcgtagccagtatatagtttt50103 gagagcactccagctttccatcccttggaaagttcagtgcgagtttctgcagttgatcgt50163 ttggatgtcatggcatccacagttccgaggcgtcttagtgaattggtagatgaagaggag50223 ttagcggaaaggccactctcagaactgttcagaaagtatattggatctgcaggtagtccg50283 gtatatgaaatatggttttatgacctatcgcctccggaaattgaagtagctctgcctact50343 accgatgctaaactaaactaccttgcgcacacagccaatgtcgcggccgaacttcggtac50403 cgcaatttagatgggaaaaggatgtgcgcacacgcagaacttattgctcgccgtcgtgaa50463 cggttcgcgcaaattctaagtaagtttttggatcttcaccaaattttaggggcgctagaa50523 ccttgttagtctggtagtattataaataagagggcgagtgtgtatggtattaagacggat50583 ccagaagaccatgaagaaagcaatgaaaccccaaggcgccagaaatcaaggagacaaata50643 ctgtcaattggtgcgcgtcgtgaatgctggattaagccttgccggaacgacagcgagtct50703 ggtgtataccagagataatgcacgtctcgcacccactggagatatttttacgcttcttgc50763 taaacttgacggtcccccaattccagcggaatatatcctagaggcaatgaatagcttcct50823 taatattggagagtcgtggctgcgtattcaaaatacgggccaggctgtcattgttgccgg50883 atgctctaccaagaccgctaattgcaaagaccaaatatggcctgcttctagtcctaccat50943 atctttagcggctgcaaaatctctgtgggtaagttcctcatcggtgaaggaaatgaaaag51003 acttcaaaagttaaaaaacgccccgctcgcaacaatgatgtacattagtttttacagggg51063 gtcgagaactgatattaccatcagattcgcattttaccgctcagactcggaacccaattt51123 gattaaaattactcgcagagtgcaagaggctatagactccgcggagcaagaagattcata51183 taaaacggcggcccttcttaaaaaaacgttgatggaaactacaagcgagatgcccacaag51243 tcactcggttgctgagtcgaagccatcacgttctattttcgagcgcgtcaccacatattt51303 tcgaatacatctaaaatgtttaaacccgaggtccttctctttacagccactgatgtgggt51363 gcttatgggtgtggcatggcctgcttttttgacactactgatcttctatttaatccgagt51423 acaggcgacgagctgaaatcataccacacctggaggcagatatgagcaggcaatctaact51483 ctcattccacgccccaaccacaggacagagtcaatgcggccgcagaaatgttgaaagctt51543 ttttattgacccctccgagagatcgagctccggactacatgcaaaccttaaacggaatta51603 ccttggatcaactcacggaagtagctcgagccttgaaaaatgaaatcccgagagaagata51663 cagttcggcaaaatattcttagaaataatatcacactcgcgctaatggctttaaaccgag51723 ctccaatgcttcgagatcggttaaatataaggcccgtatttgctcgcctttcaggccctc51783 aaggattgtggacgtttggagtgagacaacgcaccaggccaagaccgagacgctaagcaa51843 aacgcaataaatataccaatttaacccagtattatttttattttgtgtgt51893 LeuThrGlnTyrTyrPheTyrPheValCys 14901495 ttcatccgctatgcgggcctgctgatctaaagcgtaatctctcgc51938 PheIleArgTyrAlaGlyLeuLeuIleSerValIleSerArg 150015051510 gtgttttattcctttaagcaccatgcggcaggtgactgacagcga51983 ValPheTyrSerPheLysHisHisAlaAlaGlyAspGlnArg 151515201525 tgcataaatatcactgcgcgcggtgggtggcaagggactaagaat52028 CysIleAsnIleThrAlaArgGlyGlyTrpGlnGlyThrLysAsn 153015351540 ttctctttcacccgctttagactcttccgcatcgcttgcaaggtc52073 PheSerPheThrArgPheArgLeuPheArgIleAlaCysLysVal 154515501555 ttctgatggggctttgtcatttattgaggttccggaagatatctcatt52121 PheTrpGlyPheValIleTyrGlySerGlyArgTyrLeuIle 15601565 tacagcatcatcctcttccgaactagaatcaggtggagtctgaat52166 TyrSerIleIleLeuPheArgThrArgIleArgTrpSerLeuAsn 157015751580 ggatttcagatagggtgtgatcgttccatcccgcaatgcgttgtc52211 GlyPheGlnIleGlyCysAspArgSerIleProGlnCysValVal 158515901595 caattttctcaaataagtatctaaagcttgagtatcccttactaa52256 GlnPheSerGlnIleSerIleSerLeuSerIleProTyr 160016051610 cctttctccctcttcaatgcgccctttcttatgttcatcggctct52301 ProPheSerLeuPheAsnAlaProPheLeuMetPheIleGlySer 161516201625 gcgagaagattcctcgtgaagtttgtgcgaccctttgacatatgc52346 AlaArgArgPheLeuValLysPheValArgProPheAspIleCys 163016351640 cggtgtaaaatcctcgtcagaactttctccttccgggggatcgac52391 ArgCysLysIleLeuValArgThrPheSerPheArgGlyIleAsp 164516501655 ttccttgtcccacgtgtaactgtatgttgggaagtgagctatatc52436 PheLeuValProArgValThrValCysTrpGluValSerTyrIle 166016651670 ctcattatctgagcaatgtgtctgtttggcttccgcggtgtcatg52481 LeuIleIleAlaMetCysLeuPheGlyPheArgGlyValMet 167516801685 tttatctctgtggcttgttatgctttctggcgggccctcgtgttc52526 PheIleSerValAlaCysTyrAlaPheTrpArgAlaLeuValPhe 169016951700 gctagttttacgtgttgttgccaggtggcttcgatcttctggttc52571 AlaSerPheThrCysCysCysGlnValAlaSerIlePheTrpPhe 170517101715 cgggtctgtgggatgctcaaggttagtctcgtctgtaataactgc52616 ArgValCysGlyMetLeuLysValSerLeuValCysAsnAsnCys 172017251730 gaaattatcagacgggtcagaagttattgacggactctgaatttt52661 GluIleIleArgArgValArgSerTyrArgThrLeuAsnPhe 173517401745 ccaatcacaagtttctgagagtacttgttcgaattccgataattctga52709 ProIleThrSerPheGluTyrLeuPheGluPheArgPhe 17501755 ttctgttccgctctgcactggactagcaacagagtatagactggt52754 PheCysSerAlaLeuHisTrpThrSerAsnArgValThrGly 176017651770 atcataatttggatcccacagttcggtatcggtgtctgtttccgg52799 IleIleIleTrpIleProGlnPheGlyIleGlyValCysPheArg 177517801785 actcgattctgtgccagattgagttggggattcactatcaatagt52844 ThrArgPheCysAlaArgLeuSerTrpGlyPheThrIleAsnSer 179017951800 gcgcaagttgtctgtaggtgtgctaatgggcgagctttcatgttg52889 AlaGlnValValCysArgCysAlaAsnGlyArgAlaPheMetLeu 180518101815 atctgtcttcgcacataccgtgctatgaattgggcgcgggcgcgt52934 IleCysLeuArgThrTyrArgAlaMetAsnTrpAlaArgAlaArg 182018251830 acattcaccattctcaaaactacttttttcttcagaagcagtatt52979 ThrPheThrIleLeuLysThrThrPhePhePheArgSerSerIle 183518401845 gtgctctttctcactttcggatgaatcgctaggaagaggaatttt53024 ValLeuPheLeuThrPheGlyIleAlaArgLysArgAsnPhe 185018551860 ggaagcatctggataccttacaggagatttagaaatctcggtagt53069 GlySerIleTrpIleProTyrArgArgPheArgAsnLeuGlySer 186518701875 tatgacatgttcatcagatgaggaagatagcaagcgtgacggtgtttt53117 TyrAspMetPheIleArgGlyArgGlnAlaArgCysPhe 18801885 acacgattctgaagctttgaaatagcgagatttgctactcctgcg53162 ThrArgPheSerPheGluIleAlaArgPheAlaThrProAla 189018951900 tttgctcgagtgctttggatgttgggatgaggccttggtgttgcc53207 PheAlaArgValLeuTrpMetLeuGlyGlyLeuGlyValAla 190519101915 aggctccggtttcttaaaggttatccgagggggaagttccacgtg53252 ArgLeuArgPheLeuLysGlyTyrProArgGlyLysPheHisVal 192019251930 ttcttttagcttttctccatattccggtctacgggtacaaatgtc53297 PhePheLeuPheSerIlePheArgSerThrGlyThrAsnVal 193519401945 ctctggatcttcgaatattgggacatctccccctactacatcgct53342 LeuTrpIlePheGluTyrTrpAspIleSerProTyrTyrIleAla 195019551960 ataaaatatatccccaggatccccgagattagacgagaacgtccc53387 IleLysTyrIleProArgIleProGluIleArgArgGluArgPro 196519701975 cgtgtctgaaaattttactgggaggtcctcatatttggggtctcc53432 ArgValLysPheTyrTrpGluValLeuIlePheGlyValSer 198019851990 atggagccttaaaacgaatggcgatggagctgtttcgagagaaactaa53480 MetGluProAsnGluTrpArgTrpSerCysPheGluArgAsn 19952000 tatctgtgttattttgtttcccctgtcgatggcaaaaagtaacga53525 TyrLeuCysTyrPheValSerProValAspGlyLysLysArg 200520102015 cggagcatgcttgaggggtttgctggacagtacggttgataactc53570 ArgSerMetLeuGluGlyPheAlaGlyGlnTyrGlyLeu 202020252030 tgctatctgggaggccagacaggcgttctctatggggttggcatc53615 CysTyrLeuGlyGlyGlnThrGlyValLeuTyrGlyValGlyIle 203520402045 accggcaataatgtctcccaattgaattgccgtcttggcagtagt53660 ThrGlyAsnAsnValSerGlnLeuAsnCysArgLeuGlySerSer 205020552060 agaggacagcgcactttctaatggatttgttttccgtccatcgaa53705 ArgGlyGlnArgThrPheTrpIleCysPheProSerIleGlu 206520702075 aatagtagaaaacaaaaccaaaccgttatttgagcttagttcccctgc53753 AsnSerArgLysGlnAsnGlnThrValIleAlaPheProCys 20802085 ttcatatgcgatgacgacaggtgctccaaaaagaagtgaaataat53798 PheIleCysAspAspAspArgCysSerLysLysLysAsnAsn 209020952100 tgcgatatcaaaagcggttaagtcccatatggatttatggggctc53843 CysAspIleLysSerGlyValProTyrGlyPheMetGlyLeu 210521102115 ctcccgaagggaatatatcccagcacgatctacggtcccgaacaa53888 LeuProLysGlyIleTyrProSerThrIleTyrGlyProGluGln 212021252130 tttgtcatcaggggcctcgaagactcggctgagatcactgtttgg53933 PheValIleArgGlyLeuGluAspSerAlaGluIleThrValTrp 213521402145 ggaaaagtcataatcgcagcttggcgatgagcgggaaaccatata53978 GlyLysValIleIleAlaAlaTrpArgAlaGlyAsnHisIle 215021552160 atgaatcatggtatcgatgggctctccatcaatatcgtcatgggg54023 MetAsnHisGlyIleAspGlyLeuSerIleAsnIleValMetGly 216521702175 tcccatggaaacccatagtgcctccaggatattcctcgggatgca54068 SerHisGlyAsnProCysLeuGlnAspIleProArgAspAla 218021852190 tttgagggcaagaatcattagaaaggcacttgtctcatattcttc54113 PheGluGlyLysAsnHisLysGlyThrCysLeuIlePhePhe 21952200 tccggaacaaaatttttcaagcatgcatatccctgacctgacaga54158 SerGlyThrLysPhePheLysHisAlaTyrProProAspArg 220522102215 gggaaatcttttccaggggtctaaaaatctcaaaatagaggaggg54203 GlyLysSerPheProGlyValLysSerGlnAsnArgGlyGly 222022252230 cggaggttgggaaagccagtctttagggtctatcacaaaacatgc54248 ArgArgLeuGlyLysProValPheArgValTyrHisLysThrCys 223522402245 cccagctgaaggatcgaaatgctgcctaccttttgatagagggaa54293 ProSerArgIleGluMetLeuProThrPheArgGlu 22502255 agagagtgcttttttattctgagtttttctttggtaaggatcaag54338 ArgGluCysPhePheIleLeuSerPheSerLeuValArgIleLys 226022652270 agatgttattcctaccttctcgcgcactgccctagataaaacaac54383 ArgCysTyrSerTyrLeuLeuAlaHisCysProArgAsnAsn 227522802285 atctagggtatttactatgtattcagtttgctttaaataattaag54428 IleGlyIleTyrTyrValPheSerLeuLeuIleIleLys 229022952300 cctgccaaagtaaactaggtgtgcaggttcgcatgcagttaaaag54473 ProAlaLysValAsnValCysArgPheAlaCysSerLys 23052310 gattaaaatatcaatagcggttattgagtaaatgcgaactgcttt54518 AspAsnIleAsnSerGlyTyrValAsnAlaAsnCysPhe 231523202325 gtcgaattgatttttctgattgatcttatccaggtctgtgtgggg54563 ValGluLeuIlePheLeuIleAspLeuIleGlnValCysValGly 233023352340 tataaagttgcccatctcatctattattacatcccgcgctgaccc54608 TyrLysValAlaHisLeuIleTyrTyrTyrIleProArgPro 234523502355 taaagtttttgacagagtcagataagtcagggcactgtaaattgt54653 SerPheGlnSerGlnIleSerGlnGlyThrValAsnCys 23602365 acatgcggcgaccatcggagtatctgtttgtttgttcgagcttgg54698 ThrCysGlyAspHisArgSerIleCysLeuPheValArgAlaTrp 237023752380 ccaggttcgggtggaacagaaaatggtgtaagaatggaagcccgc54743 ProGlySerGlyGlyThrGluAsnGlyValArgMetGluAlaArg 238523902395 ttctatatcgctagtcctggctctcatccatagagttgccgcgac54788 PheTyrIleAlaSerProGlySerHisProSerCysArgAsp 240024052410 caatgagagggctgcattttgtctgacggataatttttttactaa54833 GlnGluGlyCysIleLeuSerAspGlyPhePheTyr 241524202425 ctcgttgtcttttggattctcaagttccaaggagagaggctcact54878 LeuValValPheTrpIleLeuLysPheGlnGlyGluArgLeuThr 243024352440 ttggtccgaagatgtgcataacgcagctgaccacaaggcggcagcttt54926 LeuValArgArgCysAlaArgSerProGlnGlyGlySerPhe 24452450 tgcagtggccgttcgataacaaagagtgtattccaggggcattcc54971 CysSerGlyArgSerIleThrLysSerValPheGlnGlyHisSer 245524602465 gttatctgtgaccatgaccgagcctattgttccgaggtggtgaaa55016 ValIleCysAspHisAspArgAlaTyrCysSerGluValValLys 247024752480 cgtaaccgtcataaccgcttttttattctgtctcatatagctgga55061 ArgAsnArgHisAsnArgPhePheIleLeuSerHisIleAlaGly 248524902495 agccctggcgagttcccggactctggaagaaaagggagtctccgc55106 SerProGlyGluPheProAspSerGlyArgLysGlySerLeuArg 250025052510 agaagatagtctcgggatgatgtcgtctgaaaaagctatacccaa55151 ArgArgSerArgAspAspValValLysSerTyrThrGln 251525202525 ggccttgtaagcaaggtaaagttcaagtcttagcagtattaactt55196 GlyLeuValSerLysValLysPheLysSerGlnTyrLeu 253025352540 tttaatatcttcatactttgctcggtaccactttggaacagactc55241 PheAsnIlePheIleLeuCysSerValProLeuTrpAsnArgLeu 254525502555 aaaaattgcagttaattctaaatggagagatttcaaagctttgaaatg55289 LysAsnCysSerPheMetGluArgPheGlnSerPheGluMet 25602565 catctctgtctttgctttaaagattacttcgtcgaatgttcgcat55334 HisLeuCysLeuCysPheLysAspTyrPheValGluCysSerHis 257025752580 ggcattagtcagtgtgatgatgttttcttctgccttttgtaatat55379 GlyIleSerGlnCysAspAspValPhePheCysLeuLeuTyr 258525902595 gggagtatattctgaaatgtctttttgatacttctttatttccgg55424 GlySerIlePheAsnValPheLeuIleLeuLeuTyrPheArg 260026052610 agttgatgtaacttgagcctctaccatttgcaaccggctggctaa55469 SerCysAsnLeuSerLeuTyrHisLeuGlnProAlaGly 261526202625 gcgttctcgtgattcctttagattgtgaactgcattgacgtatgcacc55517 AlaPheSerPheLeuIleValAsnCysIleAspValCysThr 26302635 ccatgactcttcgctggtgtctttttcttttccggaggtttcctt55562 ProLeuPheAlaGlyValPhePhePheSerGlyGlyPheLeu 264026452650 aaaggaagtggcagctgataaaaaatacttatagtaagcttcgag55607 LysGlySerGlySerLysIleLeuIleValSerPheGlu 265526602665 atctttcagacccgcgtcagcctcttcatacagtcgtttaagttc55652 IlePheGlnThrArgValSerLeuPheIleGlnSerPheLysPhe 267026752680 atccaatcgctttttaaaatcttctaatggtccgcgttcatcgat55697 IleGlnSerLeuPheLysIlePheTrpSerAlaPheIleAsp 268526902695 agagtttactagttcacatgtatcgagaatgtgagccgaagaaaa55742 ArgValTyrPheThrCysIleGluAsnValSerArgArgLys 27002705 catccattccaatgatttggggtccacggaagttataccggtgga55787 HisProPheGlnPheGlyValHisGlySerTyrThrGlyGly 271027152720 attgcttttctcttccacttcgcgaaagagattaaggaaaaggat55832 IleAlaPheLeuPheHisPheAlaLysGluIleLysGluLysAsp 272527302735 aattatatcttcaagtgattctgccctttcgatgcccggggcaac55877 AsnTyrIlePheLysPheCysProPheAspAlaArgGlyAsn 274027452750 ttccttgggcacgcgacccaatagtaaccctttcagcttttttaa55922 PheLeuGlyHisAlaThrGlnProPheGlnLeuPhe 27552760 gcccttctgcatacgcaagacttcctcttctcttacactccataa55967 AlaLeuLeuHisThrGlnAspPheLeuPheSerTyrThrPro 276527702775 ttgctccagcatgtttttaattttgccgtctgtgttctttttttg56012 LeuLeuGlnHisValPheAsnPheAlaValCysValLeuPheLeu 278027852790 ttgttccgccttgttaatttctgcggataaaaataatttaacatc56057 LeuPheArgLeuValAsnPheCysGlyLysPheAsnIle 279528002805 tcgcaacgccctgtgagaagcatcttgataggcggtatggtcaaa56102 SerGlnArgProValArgSerIleLeuIleGlyGlyMetValLys 281028152820 cacagtgacatcatcggagtgtagactgtctggcagctccttgag56147 HisSerAspIleIleGlyValThrValTrpGlnLeuLeuGlu 282528302835 tgcgatgagggccgtgggtatcacttcgccgcggtctaaccgctt56192 CysAspGluGlyArgGlyTyrHisPheAlaAlaValProLeu 28402845 tttggcattttctggacttctctctatctgtgcactctcttcagc56237 PheGlyIlePheTrpThrSerLeuTyrLeuCysThrLeuPheSer 285028552860 taattgaagctccttctttaactcatcttgcaacaggattgcttt56282 LeuLysLeuLeuLeuLeuIleLeuGlnGlnAspCysPhe 286528702875 ttctttaatagtttgaatctttgatgaaaattcgatgaattgttc56327 PhePheAsnSerLeuAsnLeuLysPheAspGluLeuPhe 288028852890 atgcgcttgcaagtaaaagtcaacaaattctgataattcaggaatgcg56375 MetArgLeuGlnValLysValAsnLysPhePheArgAsnAla 28952900 catcaattgctcggacagtcggaaaactacgcccctggtatcaat56420 HisGlnLeuLeuGlyGlnSerGluAsnTyrAlaProGlyIleAsn 290529102915 ttgagacccttctacggtaacttctgccgtttccaaaatatcctt56465 LeuArgProPheTyrGlyAsnPheCysArgPheGlnAsnIleLeu 292029252930 tgcaattgcacaaacggtcgtcaggccttctacctttgctccaaa56510 CysAsnCysThrAsnGlyArgGlnAlaPheTyrLeuCysSerLys 293529402945 taaagtttcatagtatttactgaccaacgggaatgaatgtaccca56555 SerPheIleValPheThrAspGlnArgGluMetTyrPro 295029552960 cgtagaagcggctataggagctacggctattttgtttccctgccc56600 ArgArgSerGlyTyrArgSerTyrGlyTyrPheValSerLeuPro 296529702975 tgcttctgcattaccagaatatgggttgaaggagaaaaacgatcg56645 CysPheCysIleThrArgIleTrpValGluGlyGluLysArgSer 298029852990 aagaagttttgtgccggttgcgagccagtcatttacaacgttttg56690 LysLysPheCysAlaGlyCysGluProValIleTyrAsnValLeu 299530003005 agctagatgttttagttctgtgtgggctttatgtgtactattaac56735 SerMetPhePheCysValGlyPheMetCysThrIleAsn 301030153020 atgtggtcggagatcatatatcgtttcccaatcgtctgccgaaaa56780 MetTrpSerGluIleIleTyrArgPheProIleValCysArgLys 302530303035 cttagcactgctacgatcttggaggagtgcagccttcgttgcttc56825 LeuSerThrAlaThrIleLeuGluGluCysSerLeuArgCysPhe 304030453050 cagccactcgatttcctctatggcaagtatggcattatgcgcagc56870 GlnProLeuAspPheLeuTyrGlyLysTyrGlyIleMetArgSer 305530603065 ctcggaaaggttgctacatgctttttctagagataataattccgggga56918 LeuGlyLysValAlaThrCysPhePheArgPheArgGly 30703075 aaatctttcctcattggtaagatctaactgtgccacctctttctt56963 LysSerPheLeuIleGlyLysIleLeuCysHisLeuPheLeu 308030853090 aaccctttccaccagcactgtagccgagtctgctatttgtcgatc57008 AsnProPheHisGlnHisCysSerArgValCysTyrLeuSerIle 309531003105 acgtaattctgggacattcagtttttccgtggcgttcaaaatgtc57053 ThrPheTrpAspIleGlnPhePheArgGlyValGlnAsnVal 311031153120 tttagtcagtctttcaataacatccgatagctgttttctccttgc57098 PheSerGlnSerPheAsnAsnIleArgLeuPheSerProCys 312531303135 ccgttgataagcttcagactccagctcgtagagattatcacggat57143 ProLeuIleSerPheArgLeuGlnLeuValGluIleIleThrAsp 314031453150 gctaaatagaaactgaggtatttgcgaagcccctctgttattttg57188 AlaLysLysLeuArgTyrLeuArgSerProSerValIleLeu 31553160 cacatcatgaataactgcctccacctcttgtctggcgcgagagaa57233 HisIleMetAsnAsnCysLeuHisLeuLeuSerGlyAlaArgGlu 316531703175 cccatccgcatctccatttgctttcgccgtctctatgacgaacag57278 ProIleArgIleSerIleCysPheArgArgLeuTyrAspGluGln 318031853190 aagccgttctgcatgatcgagaaagacttcaaacgctctgttcag57323 LysProPheCysMetIleGluLysAspPheLysArgSerValGln 319532003205 tgcatgtttgttttttcctccggaaagaagcgttgctgtaaaacg57368 CysMetPheValPheSerSerGlyLysLysArgCysCysLysThr 321032153220 gatagcgtcgacaagatcatgcaaatctgtggtatttagggatcc57413 AspSerValAspLysIleMetGlnIleCysGlyIleGlySer 322532303235 aaatgcacgtccatactcttccagcaagttttcgaaatcgtcccg57458 LysCysThrSerIleLeuPheGlnGlnValPheGluIleValPro 324032453250 tacatgctttccaataaaatcatcatttctagcaaggtttataac57503 TyrMetLeuSerAsnLysIleIleIleSerSerLysValTyrAsn 325532603265 ttcctcttggggaatgtttcttgtctggagcgcgctttttatatt57548 PheLeuLeuGlyAsnValSerCysLeuGluArgAlaPheTyrIle 327032753280 tcttagtccttcgaatttttttaacgggcgcaatatctgcgtcac57593 SerSerPheGluPhePheArgAlaGlnTyrLeuArgHis 328532903295 ggtacgtttcgtttcttcgtgcgcagtttcttcctttctaatctc57638 GlyThrPheArgPhePheValArgSerPhePheLeuSerAsnLeu 330033053310 tttggagaattgatctatcaaacgtgaagcgcggtcttctagcgc57683 PheGlyGluLeuIleTyrGlnThrSerAlaValPheArg 33153320 gtcaaggcgacggctttgttccacggtagttctcgcggctttggc57728 ValLysAlaThrAlaLeuPheHisGlySerSerArgGlyPheGly 332533303335 tactttgattgattcctgtgtgtgaaggacatattgcaggcgtac57773 TyrPheAspPheLeuCysValLysAspIleLeuGlnAlaTyr 334033453350 ttgggggggcgctgtaatagcttccactccctcgagctcgttttc57818 LeuGlyGlyArgCysAsnSerPheHisSerLeuGluLeuValPhe 335533603365 taattcagccagcatattttcagttagcccaaaactctgagcaat57863 PheSerGlnHisIlePheSerProLysThrLeuSerAsn 337033753380 agcgttgatgtcatgaatagcggagatccattttgtaggtgatgg57908 SerValAspValMetAsnSerGlyAspProPheCysArgTrp 338533903395 gacaagtccctctgcatgagcttcgaatagatgtagggaccatctctt57956 AspLysSerLeuCysMetSerPheGluMetGlyProSerLeu 34003405 gagtttttcatcggtggtaaggtctttcccatcgattaccagatc58001 GluPhePheIleGlyGlyLysValPheProIleAspTyrGlnIle 341034153420 tctgaaaattctcaatggctttcttgtgaacagtacttgtaagtt58046 SerGluAsnSerGlnTrpLeuSerCysGluGlnTyrLeuVal 342534303435 cttcgatgggtttcctgcaagttgcctaatcaactgaaaccgcct58091 LeuArgTrpValSerCysLysLeuProAsnGlnLeuLysProPro 344034453450 ttcaatctcctctatgttttttagccaattgacagcattctctac58136 PheAsnLeuLeuTyrValPheProIleAspSerIleLeuTyr 345534603465 aaatagagtagggatgctaaaccttcccaatactccaccgacccc58181 LysSerArgAspAlaLysProSerGlnTyrSerThrAspPro 347034753480 agatgataatgccgatatgctatagtcaatggcgcccgcatattt58226 ArgCysArgTyrAlaIleValAsnGlyAlaArgIlePhe 34853490 ctttaggaatttgaccgcagcatcctcaattctgataattgcgtc58271 LeuGluPheAspArgSerIleLeuAsnSerAspAsnCysVal 349535003505 gtcgagctttcgattaatatcctgaacgtcgagtcctgtaaattt58316 ValGluLeuSerIleAsnIleLeuAsnValGluSerCysLysPhe 351035153520 cctcaaaccctgtataattgcttgtggtatgtccggagtttgggt58361 ProGlnThrLeuTyrAsnCysLeuTrpTyrValArgSerLeuGly 352535303535 tgcttggatattgatcacatctactcctatgttacaaatttcatc58406 CysLeuAspIleAspHisIleTyrSerTyrValThrAsnPheIle 354035453550 aatgactgtccacgtattggcgagaagtgatagtactgcaatttt58451 AsnAspCysProArgIleGlyGluLysTyrCysAsnPhe 355535603565 ggcatcagcgaagcgtgcttcactttctatcacagatttcgcagc58496 GlyIleSerGluAlaCysPheThrPheTyrHisArgPheArgSer 357035753580 acgctctactacatcagtaattttgtgtccgtgtgaattaacatc58541 ThrLeuTyrTyrIleSerAsnPheValSerValIleAsnIle 358535903595 ttctattagaatactcgttttatttgaacattccagcagttcttcgga58589 PheTyrAsnThrArgPheIleThrPheGlnGlnPhePheGly 36003605 taactgttcgtacgcagttggaagttgatcacgctcggcactgtc58634 LeuPheValArgSerTrpLysLeuIleThrLeuGlyThrVal 361036153620 tgcgatttgattcaatttagcaattaacatttctgtctgcgttaa58679 CysAspLeuIleGlnPheSerAsnHisPheCysLeuArg 362536303635 cagggataaactgacctgctgcgtttttcttaaaagaacactgcc58724 GlnGlyThrAspLeuLeuArgPheSerLysAsnThrAla 36403645 cccttcactgttagagtggcatagctccaggagcaagtgtttctt58769 ProPheThrValArgValAlaLeuGlnGluGlnValPheLeu 365036553660 ttcgataagatcctgataacgcagtcttgtagtggtcaatatatt58814 PheAspLysIleLeuIleThrGlnSerCysSerGlyGlnTyrIle 366536703675 gctgatatttttctctccgatgcgagccaatagcgttgccaatgg58859 AlaAspIlePheLeuSerAspAlaSerGlnArgCysGlnTrp 368036853690 gtctattagaaggtccaccgtgctttccaagttttttgtggagac58904 ValTyrLysValHisArgAlaPheGlnValPheCysGlyAsp 369537003705 cccgttctctataataaaaaataatatgcgattgcaggtaattct58949 ProValLeuTyrAsnLysLysTyrAlaIleAlaGlyAsnSer 371037153720 caccttttcccgtaaaatcccagatcgcaaaaatctcgtcagtgc58994 HisLeuPheProAsnProArgSerGlnLysSerArgGlnCys 37253730 cggttcgaatgtctcctgtggggccggtaaccacttaagaggatc59039 ArgPheGluCysLeuLeuTrpGlyArgProLeuLysArgIle 373537403745 ttccaaggcattttttattggtgttatggatcctaattcaattgt59084 PheGlnGlyIlePheTyrTrpCysTyrGlySerPheAsnCys 375037553760 tgctgatgggtttgtgtcttctgccgtaagtaaattccaagatag59129 CysTrpValCysValPheCysArgLysIleProArg 37653770 cttcctcctggcgctatgcggcttagtattgctttgagcttctgg59174 LeuProProGlyAlaMetArgLeuSerIleAlaLeuSerPheTrp 377537803785 gtctgaacgtacggagtgttttctttgttttcgtggtgtgaggtt59219 ValThrTyrGlyValPheSerLeuPheSerTrpCysGluVal 379037953800 tgtcagtttttctgagcttccgatttgatcaggattctttggctg59264 CysGlnPhePheAlaSerAspLeuIleArgIleLeuTrpLeu 380538103815 tggcttctgtctcttttttgatcttggtcttaccggaacgctcca59309 TrpLeuLeuSerLeuPheSerTrpSerTyrArgAsnAlaPro 382038253830 tggagcaatagcctttctacggtccgcgagttcaaaaaggttctt59354 TrpSerAsnSerLeuSerThrValArgGluPheLysLysValLeu 383538403845 ctgagaaaactctgggtttagtccgagagcatagacatgcgccgg59399 LeuArgLysLeuTrpValSerGluSerIleAspMetArgArg 385038553860 aaatggatgaattatttgtgtgcttaacgtaacactgcttaattcagc59447 LysTrpMetAsnTyrLeuCysAlaArgAsnThrAlaPheSer 38653870 atctgatgcgccatatgatgccattactgatgccgcaatgatttc59492 IleCysAlaIleCysHisTyrCysArgAsnAspPhe 387538803885 ctggagcgttttctccgataccttttcttcgtcccacccatccgc59537 LeuGluArgPheLeuArgTyrLeuPhePheValProProIleArg 389038953900 attgaaccagtagagaaaattcatatctattccaactccagacat59582 IleGluProValGluLysIleHisIleTyrSerAsnSerArgHis 390539103915 attctttacatatgcccgaacaaattctgggaggtcatcaattct59627 IleLeuTyrIleCysProAsnLysPheTrpGluValIleAsnSer 392039253930 ccttagcttgcatacataagcacttgacatttcccatccatgtgaatc59675 ProLeuAlaTyrIleSerThrHisPheProSerMetIle 39353940 aaaaatgtacacaggatcgtcctttcccccagaacacacggctgc59720 LysAsnValHisArgIleValLeuSerProArgThrHisGlyCys 394539503955 aactcccctgtcaccgatgatcattatgaatcccaatcctttcct59765 AsnSerProValThrAspAspHisTyrGluSerGlnSerPhePro 396039653970 aattttcttggcaatgattttggtaatgccgtgtatattcatgga59810 AsnPheLeuGlyAsnAspPheGlyAsnAlaValTyrIleHisGly 397539803985 agatgggaaaccttcgattgtgacttccatgtcataacccacatt59855 ArgTrpGluThrPheAspCysAspPheHisValIleThrHisIle 399039954000 cccgtatgttatagaaggtatcatgagcatgtcaggttcatccca59900 ProValCysTyrArgArgTyrHisGluHisValArgPheIlePro 400540104015 tgatgatctccagagtctgggaagttcgtgacaatcaatcattcg59945 SerProGluSerGlyLysPheValThrIleAsnHisSer 402040254030 aaacgaacatttttttgacttgtcctccaccttggccttccctgt59990 LysArgThrPhePheLeuValLeuHisLeuGlyLeuProCys 403540404045 tctcgtaatctccgccccctggtctaaaatcgcatccaaactgtc60035 SerArgAsnLeuArgProLeuValAsnArgIleGlnThrVal 405040554060 cgcagagagcatcgaatcgatcccgtagcattcgcacccccgcag60080 ArgArgGluHisArgIleAspProValAlaPheAlaProProGln 406540704075 gaaggcggcggacgtctccatacacatatagtatctaacaggttc60125 GluGlyGlyGlyArgLeuHisThrHisIleValSerAsnArgPhe 408040854090 atattttcgagcaaattggctggtcgacgcggctacaataaattc60170 IlePheSerSerLysLeuAlaGlyArgArgGlyTyrAsnLysPhe 409541004105 tccgaatgccggtggtaatcttgtcggaggatggaaatcctgagc60215 SerGluCysArgTrpSerCysArgArgMetGluIleLeuSer 41104115 catgttcgtgacctgctagaactgtacatcagtctgcttctggggccttttat60268 His 4120 ttgtttgggaagagtttcgtaaatgtctagccaaccgcacacaagaacgcgataaataca60328 caccactcaattactcattagtctttctttattcaaacatttttacatttgc60380 LeuPheLysHisPheTyrIleCys 4125 actttccaaaactcgatcggaaactgtcagaagagtctctgatga60425 ThrPheGlnAsnSerIleGlyAsnCysGlnLysSerLeu 413041354140 gattagtttgtctggaagtgtgtctacacacccattgtctatccc60470 AspPheValTrpLysCysValTyrThrProIleValTyrPro 414541504155 ttcttttgtcgagtgtcgaacatagagcggggctttgttggtttt60515 PhePheCysArgValSerAsnIleGluArgGlyPheValGlyPhe 416041654170 atcccacgaagtaatgtctgacgcctcggtaataaattgatttgatga60563 IleProArgSerAsnValArgLeuGlyAsnLysLeuIle 41754180 tgtatcttgatatcccctggcatcaggcggccctaaaagagtaag60608 CysIleLeuIleSerProGlyIleArgArgProLysSerLys 418541904195 agctgacgctgtatcttctttagaaggggcagaaatttcaatttc60653 SerArgCysIlePhePheArgArgGlyArgAsnPheAsnPhe 420042054210 ttccaattttccttcaagggtcgtggtccctccctcctctatatc60698 PheGlnPheSerPheLysGlyArgGlyProSerLeuLeuTyrIle 421542204225 tagcagagctgatgccgcgccaataactttaactacatcttcagg60743 GlnSerCysArgAlaAsnAsnPheAsnTyrIlePheArg 42304235 ttttggattagatgtctcgagagcagcttcattatctgaaaaagt60788 PheTrpIleArgCysLeuGluSerSerPheIleIleLysSer 424042454250 tttccaggcttttaccacatcgcgggccctttttaccccgacgcc60833 PheProGlyPheTyrHisIleAlaGlyProPheTyrProAspAla 425542604265 tgcgagtgaacgacataatgtccacgaacgctggacgacagtatt60878 CysGluThrThrCysProArgThrLeuAspAspSerIle 427042754280 cctcgcgtccgctatgccagataattcttcagctactttcctaca60923 ProArgValArgTyrAlaArgPhePheSerTyrPheProThr 428542904295 aatgtgagagcgtgtttgagcattacccgcaagctgccagtatgt60968 AsnValArgAlaCysLeuSerIleThrArgLysLeuProValCys 430043054310 ggtctcaagtgcatgcgttttaacctttgtggaatctaatgcccg61013 GlyLeuLysCysMetArgPheAsnLeuCysGlyIleCysPro 43154320 aatagctttttctgtgtgccggattgcagtttctgcaaaattgac61058 AsnSerPhePheCysValProAspCysSerPheCysLysIleAsp 432543304335 ggctttccatatggcctgcattacagtatcgtccttccagtgtcc61103 GlyPheProTyrGlyLeuHisTyrSerIleValLeuProValSer 434043454350 tagttcttttttgtcacggcaacttgagaaagaaacattgcccaa61148 PhePhePheValThrAlaThrGluArgAsnIleAlaGln 435543604365 aaaatccgcatttgctgactgtgaaagcagtgttcttatggtagc61193 LysIleArgIleCysLeuLysGlnCysSerTyrGlySer 437043754380 agtcttagaaagtagtatttgcactgcagtagatatctgcataga61238 SerLeuArgLysTyrLeuHisCysSerArgTyrLeuHisArg 43854390 tgcgttatttagagtcttggaaacctcctcaaggtctctcgttgc61283 CysValIleSerLeuGlyAsnLeuLeuLysValSerArgCys 439544004405 agcttgctcgaatgcctgggaaatgaactttgatctcatggtatc61328 SerLeuLeuGluCysLeuGlyAsnGluLeuSerHisGlyIle 441044154420 gacggcagggacaggctggactgttttcttaaatgtttctggaag61373 AspGlyArgAspArgLeuAspCysPheLeuLysCysPheTrpLys 442544304435 agtgtcgaggctcctgtcgcatgcgtcagaaattttaagcaatgc61418 SerValGluAlaProValAlaCysValArgAsnPheLysGlnCys 444044454450 tttttctatcgcgcttgcactttcgatggatatcttttctgtcgg61463 PhePheTyrArgAlaCysThrPheAspGlyTyrLeuPheCysArg 445544604465 attggtctttgtaataaatggggagaccgctaactgaaattccaa61508 IleGlyLeuCysAsnLysTrpGlyAspArgLeuLysPheGln 447044754480 aattgctcgcctgtacttctgagtatcagacaggttttctgagag61553 AsnCysSerProValLeuLeuSerIleArgGlnValPheGlu 448544904495 cccaaaatctctagcccacgataaaagctttaccgcgtgttgtac61598 ProLysIleSerSerProArgLysLeuTyrArgValLeuTyr 45004505 cgcgtcaacggtgaatggataagttgatactgcgtaaacaatgtc61643 ArgValAsnGlyGluTrpIleSerTyrCysValAsnAsnVal 451045154520 tctcaatacggtcgctacaaaaagattggaaaagagttgcatatc61688 SerGlnTyrGlyArgTyrLysLysIleGlyLysGluLeuHisIle 452545304535 gattttcgggtccgttccattgcgcgaacatatctcttcaggctc61733 AspPheArgValArgSerIleAlaArgThrTyrLeuPheArgLeu 454045454550 cgcgcccccaacttcaatggcctggactaattctacggtttgctc61778 ArgAlaProAsnPheAsnGlyLeuAspPheTyrGlyLeuLeu 455545604565 aaatccataagtgtaggattgttcgtcggcactcgcatacccctt61823 LysSerIleSerValGlyLeuPheValGlyThrArgIleProLeu 457045754580 atctctggccttttccctgcgttcgagccaatccaaattttcctg61868 IleSerGlyLeuPheProAlaPheGluProIleGlnIlePheLeu 458545904595 cgtctttcctcctaagtcagatatgaggcgttgtacaaaatcgaa61913 ArgLeuSerSerValArgTyrGluAlaLeuTyrLysIleGlu 460046054610 caccaccaaatctccaagcgcctcggctcctccatcgctcccatc61958 HisHisGlnIleSerLysArgLeuGlySerSerIleAlaProIle 461546204625 tataactgaggccagagtgtccctaatgatgtttagagcatcttctga62006 TyrAsnGlyGlnSerValProAsnAspValSerIlePhe 46304635 tggggctggggcaaatgatcgtagtggtagtagttcgctttcaga62051 TrpGlyTrpGlyLysSerTrpPheAlaPheArg 464046454650 cacccctacccgccggagaagatgcgaatatgggtctacaaaatc62096 HisProTyrProProGluLysMetArgIleTrpValTyrLysIle 465546604665 agatataagcccagcgtaatgccctgaatactgtagcgtccgcggatt62144 ArgTyrLysProSerValMetProIleLeuArgProArgIle 46704675 atatgtatacattgagtgcgcagcgagtcctataagtgatgtata62189 IleCysIleHisValArgSerGluSerTyrLysCysIle 468046854690 tacaacggctcctaggaaatctccaatgattgttccgtcagtatc62234 TyrAsnGlySerGluIleSerAsnAspCysSerValSerIle 469547004705 ttcaccccaaagcgcctcagccttttggatatacagttcgcagtt62279 PheThrProLysArgLeuSerLeuLeuAspIleGlnPheAlaVal 471047154720 gctcttggtaaaccccctaagcactaaagtacgaattacttcctc62324 AlaLeuGlyLysProProLysHisSerThrAsnTyrPheLeu 472547304735 tgggccaccggtagcggccaagtccggcaaacgcgccatcatatc62369 TrpAlaThrGlySerGlyGlnValArgGlnThrArgHisHisIle 474047454750 ggcggtacttgttgtataagcagttagggtctccttttgttcctc62414 GlyGlyThrCysCysIleSerSerGlyLeuLeuLeuPheLeu 47554760 tgtcaagttattaggcgcgtcctcgaaaagctgtacgatggttgg62459 CysGlnValIleArgArgValLeuGluLysLeuTyrAspGlyTrp 476547704775 gacatctagggcgaggcgtttaatgggaatagttaatagactatc62504 AspIleGlyGluAlaPheAsnGlyAsnSerThrIle 478047854790 taagtcgtgccgccagcaaactacatgtccaggaacatgcgtctt62549 ValValProProAlaAsnTyrMetSerArgAsnMetArgLeu 479548004805 cggaggatctcctaacacgagtagtgggtctcgactgtatgcagcatt62597 ArgArgIleSerHisGluTrpValSerThrValCysSerIle 48104815 ggcgtacagttgcgagatagaaaagtatcttgagtccaaatcttt62642 GlyValGlnLeuArgAspArgLysValSerValGlnIlePhe 482048254830 agcgatccatgacttggccgaatctgtgtccagatcaaaggcagc62687 SerAspProLeuGlyArgIleCysValGlnIleLysGlySer 483548404845 tagcgccgtctgtggaaacttccgataagggggttttactgtagg62732 ArgArgLeuTrpLysLeuProIleArgGlyPheTyrCysArg 485048554860 ttcaaaatactctctgaccatagagagggtcatcagcgctttagt62777 PheLysIleLeuSerAspHisArgGluGlyHisGlnArgPheSer 486548704875 tttgggtagcccggttgaagccgtgatataatttaacattgcatggta62825 PheGlyProGlySerArgAspIleIleHisCysMetVal 48804885 tcccactaagccttgtagctttgttccaagatactgtatcccgtc62870 SerHisAlaLeuLeuCysSerLysIleLeuTyrProVal 489048954900 ttgaaccatttggtggtcgtataaaagtggataattttcaattaa62915 LeuAsnHisLeuValValValLysTrpIleIlePheAsn 490549104915 aggagataggagtttggttggctcgagtcggtctccggatgtctc62960 ArgArgGluPheGlyTrpLeuGluSerValSerGlyCysLeu 49204925 gaacaattgtcgctcgtcaactaccaatcttgccaaactcccaaa63005 GluGlnLeuSerLeuValAsnTyrGlnSerCysGlnThrProLys 493049354940 ttccgttaaccagccactaattagactccaatattctacatttgg63050 PheArgProAlaThrAsnThrProIlePheTyrIleTrp 494549504955 atcatttaacccaggaaattctttacgtacagctgtttctaggtc63095 IleIleProArgLysPhePheThrTyrSerCysPheVal 496049654970 atgttgcagtccagtaaatgcttctctcaaatattgaattattct63140 MetLeuGlnSerSerLysCysPheSerGlnIleLeuAsnTyrSer 497549804985 gaaatcttctccagagttccatggaacagatatgcggctaataag63185 GluIlePheSerArgValProTrpAsnArgTyrAlaAlaAsnLys 499049955000 agagcgtgcaaataatttcaatgtaacgtccgctactgccggagg63230 ArgAlaCysLysPheGlnCysAsnValArgTyrCysArgArg 50055010 cgccattgtgcatgcgagcattatagtttcaaccatgtttttcct63275 ArgHisCysAlaCysGluHisTyrSerPheAsnHisValPhePro 501550205025 agcttctactttctccaaatcttcaagtggaattctgtttctgga63320 SerPheTyrPheLeuGlnIlePheLysTrpAsnSerValSerGly 503050355040 gattagaattccggtgagggctgaagtaacacccggaactttact63365 AspAsnSerGlyGluGlySerAsnThrArgAsnPheThr 504550505055 gcagtcggtgtgtacagcttcaaggcaagccttgaggctatccgt63410 AlaValGlyValTyrSerPheLysAlaSerLeuGluAlaIleArg 506050655070 gatggcctgcatggtttcaatagtcgcgtcaactcacggaaccagctggtag63462 AspGlyLeuHis 5075 ctttataggcacgcttctgaatgctttcacagcacagtttttttcagaagtgtgattaga63522 gccagtgttctccagcttataataagcgtcagaacttcctttccgcgctgttacatcgta63582 agcatgtccggattacttgctcgcaatggatcgaacgataaaattcgagcgccagaaaga63642 gggctgagtggattcgcaaacactcgcactcatccttatttacaaagtgtacttcctcga63702 agaactcaccagcataatctgttatcagccgcgctggggcgcctaacaactggccggaat63762 ttttctcatggtcttggaacgaggccagggaaattctttattggctcggggccacgtaac63822 cccgaagaaacaaataatgcaacgcttggaaaggaagatacaagggccatcgcatctaaa63882 attcttctcgatgttgaatctacgaggacaaatgatgtaatttctttaacccaaataact63942 gtcatagacctctgccagccaggggtcgaagagtctgggtctctaatgctctttttgaaa64002 ggggttaaagacttactcaagattttgggatcacgacccgcccgcgagcaaattgtgaga64062 gatttagagactgcatttatcaatttgaaccgcgcctgcggcttatcggttactggggag64122 agtgctgtcaaatccttcgagctttcagcggtgtctttgagttttgtagctgcggccggc64182 gcggctcactaccgaaataattgcggagtagaggcactacgcgcgttcgtaatcgcgaat64242 tataaggattccgccattaccgaaaagcttgccaattttgatgcattgcttctggcaaca64302 attgaggcacgagcgtacccccattttttactatctttaggtgggggcttgataaaagct64362 accgaaagtgaaacagtaacgtgcatgcgactcttggtcagagggactcacgaagcagca64422 gctgccggagatctttctgagaaaaaatgtgccgtactccacttccctgcatgtctgtta64482 cttgacctcgatgaaggtttttgcccaccaaggacaaagatcaatgcagaaggcggtgtt64542 tactttctacatttattattcctgtactctaccgatatgggacacccgagctacgaacta64602 tatgtggcaaaaacatctctccccgaaagttgcatgagagacattttaaatgaaagattt64662 acacgacgcagaataaataacactatagcttccttaacacacatgcaagctcaagaacgc64722 caagcctttcccccttttaatattgcagaagctgcggttgccgcgcgaatggatctggga64782 cgagaaagatcaagacatccactggatccagttcaaggtcgtgatcaacgtcttagggat64842 atgcagataacgtccactggaataccagaccattcggctctagtattcgccgcatactgc64902 atgctagggacggcgggcagtattggcggggagccttctttttctactatccagaaaaac64962 gggactagtctaaagtatgttcacattcgcgattttaactttaggggcggcccatggaat65022 gtttgtatgtaacacacccacttctaaataaatacaagtctgttcaccccatgtgtctat65082 tcagttctcattcgaggcaagggagcaaggatccctctcaggacaattataggattatct65142 cctgagcagcccggagccatgctttcgtttttcgatgaactcgaaagcattgcccatcta65202 gaagagtgtctgcgggacatcgaaacgcgtatgcgaacgtctgggtttgatcctaaatcc65262 atcattagagacgattttgacataagggctgggcgcgagggcctcgccaaccggatctcg65322 atgcttgtggacgggtttaaagtttccgtgctatttaacgtagaactataccgactcctc65382 gcggaactcgttcatttaagaattcgcacaaaagcagtctcattttcggagtggctagat65442 actagggggctatctgcggactgtaaacaatttattttggaaaatgcagaacatatttct65502 gcggtcgtcaaagacttctacaacggaacataccatcagcttgcaagagtcggtcttcag65562 tcagctcaaaaatatgaatcgctgtatttgggaaaacttggcaatggaaagctggagagt65622 atgggtcaattttttactagactctctgctgaggctgccagaggagcttttaatattccc65682 caatttgcacaggcattggaagttgatggccaggttacaccggcagacgtctttactagg65742 ttttttacgtgtttgagtagccaactgatcgtacctcctaccccagtaatgcttttcggg65802 ggtacgtctctggctgcttatgccagttgttttttgatagattcatctggcagaaataca65862 agagaggcgttcaatgtcgttgccgaagaagtaattccgatcatgaataatcgcggagga65922 attggaatatcactgccgtgccttggcgctccccaaaatgagtcggggtgcctgggattt65982 cttaaggctctcgattcgctagtagccgcgagcaacggcgccgcaaagcggccaacaggg66042 ctttgtgtttatttcgagccatggcattgcgacacattaaagattctgaaaattcgtggc66102 agctcggccgggaatgaagagttcagatgcgataacatttttactgccatttggatgcct66162 gatctttttatgaaaagactgcagcagccaggaagtaaatgggcactgttcgaccatagg66222 ggggagcatctgtctaacttgtttggagaggagtttgagaaggagtatgaacgtcttgaa66282 agggaaaatgttggagtggccactatccctatcaccgagattatgtttcagataatcaaa66342 agtgcagtttccaccggcactccatttgtcgtctttaaagacgccttcaaccgtcactat66402 ttttacaatatgcaacaccgagcactgaagtgttctaacctctgtacagaaattgcccac66462 atggcagactccgatactgttggagtatgcaacttgattagcatcaatttggcggcaatg66522 gtcaaaaatgctcgcgcaggacttgctgggaaacccggcagcttcttcgactatgaactc66582 ttaagggaaacggcaagaactgcaacaattttcgccaatgtcatgatatcacttggaaac66642 atgccaagccaacgggcacagagcgggaaccacaggttacgatccctcggtgttggagtc66702 cagggactgcacacagcctgcttaatgcaaggttttgggatgactagcgttgagggcttt66762 gaatttaatgacactgtgtttgagctacttgccttggaaacaactggaatcagctgtaga66822 ttgtgtgagctggggttgcctccgtttgataaatatagagaaagctattatgccttagga66882 tggctgcatattgatgggtggcccaatacgaagctgagatacaaaaatgagtgggatagt66942 ctaagacatagaatagatcaatctggtttgtacaactgccaaacagttgctttgatgcca67002 accgccagttcttcccaaattacagaagtcagcgaggggttccagcccgtattcgggaac67062 atgtttagtaagatctctactacaggagaggaagtgcgaccccatttggcgctaatggat67122 gccatcgacgagctgtattctgaccagggagaaaaacaagcatttctagcaaacctaaaa67182 aaacatcagtggtctgtgcgcgctgctctgggaagtgcttggtcagagtctcacgtcctc67242 gcgaaatttcaaaccgcatttgaactcgatcaggaaaagttactatacttaagcgcacgc67302 cgcgctccattcattgatcactctcaatcaaacactctctacatcaccgaagacgtggac67362 ggtactttaagtgcgtcacgtgtatcccgcctactgcaagttgcctttaaatacgggctc67422 aagactgccatgtactactgcaaggtgcgcaagatcacaaacaacggagtgtttgtcggg67482 tcttgcggagacagcctcatttgctctgcgtgtcaataatcttgctaacatggcagaata67542 tcagtccacagactattattacttgccccagtgtgatgacattcgcgagctccgagacct67602 gagcatagcaaataactggaacgaatttgaactatgctacagtcgcgatgagaaagatgt67662 tgatctactaactccggaagaactagatttttacaaattcgtgtttgcatttctggcagc67722 cgcagacgatttgataaatttggatatcgggaatctcatgactttgttccctcacaagga67782 cattcaacactattatgctgagcaaataagaatagagacggtccactctagaacctacag67842 cttggtgcaaatgatccttttcaagggagaccttcatgcgcgagacagatatgtgacaga67902 agctattaaagatcccgccataaagaagaagatagactggctcaaccgtgtccaagtaga67962 aacggatctgacacttcctgaaaaatacattctaatgattctccttgaggggattttttt68022 cgtggcgtcctttgccgcgattgcgtttcttaggaggcggaatatttttgtggtgatgtg68082 ccagtcgaacgacctcatcagtcgcgatgaagcggtgcatacaacagcatcatgccgcat68142 ttacaacaactggctcggggatcacaagaaaccatcggctaaacgaattcaccaactttt68202 caaagaggccattgaaattgagtgtaactttttagcatctagagcgcctcaagcttcgag68262 actcatagatctagaagccatacagagtttcgtgagatatagcggagatcgacttttgac68322 cgccatcggggttcccactatttttgatgaaccgccccctgatccgtcgtttccccttac68382 cctgatgtcgatcgacaaaaatgtcaatttttttgagcaccggagcaccgcgtataatgg68442 caacgttatcaatgacttgtaaaagaaagttcaaacagtcaagcattatataaataaaaa68502 ctactcagacagatattaacattttatacttgttcttgttcattttttccacaaataact68562 tctcgtaatgacggcagaggctttagatgccccttcttaataagctcagaaaaatatttc68622 ggggcatcattagaaaagtatttacacaatacttcatatacagcgatcatgtcgagctgt68682 tcctgaaccacgggcacgcgcttaagtagtttgtgtctgccatttatttctcgtgggccg68742 atgacactcaaaacgtaggacagaaactcgtcatttttttcatttctggcgccattattt68802 accgaaggatcctgagggcggtaatcaatgtccgagttaccatcgtcgggaggttcttga68862 ggaaactgagtcagtacatatacatagcgtccaggcaaaggttcacgcacatctgttttt68922 attccaaaaacatcactatccgcaggcaagaccccgcgctgctcaacacactttttggta68982 tcgttgttttcatttttttcgtggtcacgccattccgccaacctggcagaaaatgagtat69042 attgaatcggtagaatggatgttagtatgacagtccacacatgcattggcaaactcttcc69102 ccggacatgcccaaatattcaataatacttttataaaagatagcgactggaaatgctggg69162 gtcagatccgtaatcacatcacaacccatgaatactaagtcactatcgctagacaggacg69222 tacgccaccgtgcgggtatggaatagattggcacatgcatagtcggcttccattccttgc69282 acatagaccgtagcaaatcctgcggtagttattaagtcccaacataacttgtagtgcgga69342 ggacgtatttttcgacgtgtcttgtaaatacaatccttgggctccttaatatcgctgcat69402 cttcgcgcggcaggtgcagtcggaacagattcttcctggctaaggtgtttaggttccttg69462 tattcgcgccgacgcccaccatcaaaaacaaatacaggatagcacgatttccgactgagt69522 aatgaaaataagaacaccaaacttttaaaagttctctccatgcatcccatatttccgtcc69582 gggtcaattcttcgcaaaattagaaaaagaacattccatgtgtcgactgccagtggaaga69642 taaaatcccttctcaatttttaacgataaatgaacactgagtccatggtttcgaataaag69702 cgacacattcccaagattcccatatcggtatatttcgaggagagcaaatgaaaagacaga69762 agcccgcaagtctcgtatcagcaaactaatatttagggcgctttgaaaggcggtatttgt69822 atgtacaggggttgggcaatccacaccctcgtaatcgcattacacataaggtgtgacatg69882 gtggtagccccaaaattttatgcacaggctacagttgtatataaaccgcgcggatgttta69942 ggagatgttcagagacaccggggaagggaacgaacgtacacacgaattacgttcgttgga70002 agatggatttggatactgcgacaagaagtaaatgtttgctccgactaactttaggaaagc70062 atgggatttcggtggtttcccccattgccaaaaacatgcgtgggattctgcaacactctg70122 tgctggcttttatgaatgactgcatagtaatttcctgttccgctccgtttgggatggctt70182 tcttaaaaatcaagtggcaattgttcgactcatttgaatatttatcagacgatgagagta70242 tactacctatcatgttcaataatactatacaccagcgccctggagacctcttggattttc70302 tgtgggactctaagaaaaaaactgtcggaataccaactttagccacatttactatatcag70362 aaagtttcaaatccgatgaaactagggctgtactcagactgaaagtctgtcgcgagatag70422 aagagagcgcgtcgtgcccccaaaatacggaaataagcacgaaattcaagtactcttcat70482 cggatggacctcctatatacctgcctcgttccgataaggcatgtcgggcctcgctggaac70542 agtattcgttcaatgaaattacaaagtggctttcgaagatccctaaagataactcaatta70602 cagtcacactcacaagagagtatgtcacgttctcgtccgcagaagacgagcaacgcctaa70662 cctttaacgcgaaatggttcggcgaccagacaagtattgtatcgtctgcgtcaattttgt70722 ctcagctatgtggccatgaacctgcgcctaaaaaaagagagctctcaagccgagccatcg70782 gtaagaaactaaaagaagcccgcattatcgctgttcatggggacaaagatgcctgcccca70842 ttgtagtatcactctccagacccggatctctgaaacagtcactagggtggctgaaaagcg70902 gtccttggggaccaccgtgtcttacattttacaaagactctgtgaatagtcttggagtag70962 aactctctgaaagaggaggagaagaattagctgctgggatttttttcctttccgcgtttt71022 ctgcagatggagcaatctctgagcaatgccatgatgactcagacacagccatgcacgaat71082 ttttggcggaggaggagcgcctcatacaacagaccacgctatcccattccaactcaagta71142 agaagaggtcgctcgaaaattacgaggacaccgatattagcccatcccaccacccacaaa71202 agcgggggaaattaaagaacggctcacttgcacggaagaactaaaatcgtctcctcgcgt71262 ctaccggggagcttagtttactgccagcgtttgtgacccaagtgtgcaccgtgatttcaa71322 ctctaccgcaactatgacgggggctaccataattgatccattcgcaccgcccaagggtaa71382 atggtggccgttcaatttgaacgggatagttttttccttgatgatgtttattatattttt71442 agcctggatactgtgcattgactatggactcgcgttagcttacattacctgggcaaagct71502 ttctacgaaagaggcaagattcggatggatgatcggactattggtggctacgattactgc71562 cagttttctggatattcaatactcggctcacaaaacagtccgaatttattttctggtgat71622 gctttctatggcgagcgcagtaataattatatttctcatccattccaacagccccaatgc71682 cgcgatagttatggggctattctccgttttttcggaagtttgcttgatactgattttggg71742 atttcaactccgaccggccattttctgcagcataaacatgacctggctctttcttgaagc71802 catgctcctaaatttgaccgtactttcttggaacttgatgcaccttcgagtaaaccctag71862 atacttggaaccgttggccctttttactattaacattttggcatacaatccctctcgttt71922 tttgctcaagagtgatttttttaagaccagcatgataactctgacgggcagtatagaacc71982 attttccgaagataacacgatttatacacccccaagacaacataaagatactcgcccttc72042 actgaatgacggaccaactcggtggtgcggttactgtattctcgtatctacaacattggt72102 tactgccgctttcgcctgcacattatcattaccgttcctgggcaaagatttaggtactgt72162 acgcatcggcatgcaaacgaattttaaaatcctcatggtagcgtgcggttcggttttggc72222 atttggatctacttgcattggaaaactatgcaaaatccatatcgttgtatggttcgtgat72282 aagcatactattaaccttcgtgtctctgctatcactgattaagttgattgaggacccagc72342 tggcattccatttggtgtcattcttgcatcggtttcttgtctgtttcaagttggagccct72402 ctttttccgagaattaaaaacggccacccatacacaaggatggatttcatgcgcccttct72462 tttctgctcccttttcattccaattgccgcgccgcttgtgtgtgagtacaagctctgaat72522 tcttgtctaagggagacgtgccaattctgacaacgccctaagccaacacaaatgccttcc72582 tcaatttacgcgctagcttgaacattccaacaagatgaatgcatcgctaacatggcttgc72642 tttaacttttaaagttaccttgagtttcagcctgctctgaatgttttcctccaaacctaa72702 gatgttcttagttgtacgatttttgtattgcgaataccacatcatccagtaccaaagtac72762 taatggtcggcaatcgaatagaaatcaaacatggcacgcaggagactgtcgcctcgaaac72822 tgccttcgccgagctgcagaaattcggaacgaggacattagaaacagatctacattccac72882 cgagcaaccgtttactggagaaaatgctagagaataacctaacaggcggccttcaacttt72942 cactacttaacaactggaactatattgtcgaggattgtcatagtcacgaacatgatgcag73002 tattgcttcggatgcaatctatattttgacattgttaataaagcacatgtactatgcaaa73062 gtttgcattcgtgtaattcgtcgagagagaaagttacaagttcgattctctcgcgctagg73122 agtgtttccacgtgcgaaaacgcaaaaattttcatattattcgggcggactgtgtccata73182 gtagctaaattaccgcgatctggagactagggcattcacgactcaacatgcagcatcaga73242 gtactgcgctagtttcgagtatacttttgctcttgagcctgcaaagccttgcgtttgaat73302 ttttctgtgatccgccacacgtttttcgagggcagctcggtgaccccattctattgcaat73362 gcttcagcgacagacctctaacccacgaagaatctgtaaaagtagaagtaattcgacacc73422 cagccagcttagttgaaactgcgctaagcgcctacgggatccccccttcgctagatccat73482 ggagagctactccaagaactctctacacatatgatgccgctactgattcaatcaaggacc73542 taggatacattggtgaagatggaattaacccaccatatttggacgactgtcgttcaggtt73602 ttttcaatgtctctatcaagtctagcatgagatctcacatggcgcgttatcagtggaccg73662 caagtcgagggtctacaaaactaaatagctcttttatcgacgtctttttggcaagaccac73722 ctacaactgtccgcatcaaatcagaagaactgtacgaagactcagataaggcttcgcact73782 taagtgttgaagcgcttggcgcttatcctccatctgctgcgctgggtacatggatgatac73842 ataatgcatctcttgctgaaaaatacagtttagaaagaagagttctttatgcatcaggag73902 agaatggatcggtggatcagacatgggaactggaaatacgtggagaagccagccagcccc73962 tcccttccaaaattcaatttgtatatcgatggacccctcctgaggactttgaaatgctac74022 gacctgaaactcgcttgttaaggttgactcccagctggattagcaagccccgcatcacgg74082 tacaattcgtccctcctgcctatgccctgtgtagagcagctaatattatagacggccgag74142 gatttattgaatggatcgtagataatagaatttcgacgagcccacaccagacctttgttt74202 tggatgagcccgaggggaaaaatatcgttacactaatggacgtcataaaactaccaccgg74262 aggatacatttcaatctgcctctaattacgtgtgcgtcataagaggctatgaacatgcat74322 acagatatctcaacgcctccttaatgatagataatctgccaatgcggcaaggattccccg74382 cagtcgctgcgatttttattataattagtatcgcttttgtgggtgggttactagttgctt74442 gcttgggcgcatggtgctggaagacaacataaacgctcatttaataaatgacattacaaa74502 cgtgcactactgtctgtccaatttatttcatcggaaaccttgcactggcaggtagtctca74562 agcaagcctaaacgatattatagatttcaatatttctaccagatccgtccgatattccca74622 aatgattggagaaatttcttccttagtcatcttccacagatcttcgattttgcgcccaag74682 ctcaaaatttccagtaatttcagaaacctcactggccgcgtatgcctcctcgtacaagta74742 aatgcagacgagagccgcggcggttcgctttgcagtgttgaccaaaatttcttgtggaat74802 tttagttcgaaggcacgctgcggtacttacatctttcattaaacgggtttttgccgcatc74862 gaggagtaccgctgtttctgggattaacgggatactctctggtggatacgaacatctcgg74922 tttgggttgcactttgggattcaaacaacagctgactagtgcatcttgcaaaacatagtg74982 cgtggccagcaaagttttcaatatattgagaacaacttccgacaattcttgtaattgtag75042 agtttcggggctctggatttttttgagcccgcttttttcaatatatctttcacagacaac75102 tgtaatttcgtcaaagtgacaaggatagtgcccgagcataagtaaataattaaacagagt75162 ataaggaatcactgagcttcgcccgaatgatgctttgctgaggcatcgttggccagggta75222 tggcagcgtgaccagaatgtcagcctcgtcgcgcaatgtacttttcagttttgctccatc75282 agtctcccatgaaagtccgatagttgcgagaagtccatgtcgtgaaatcgtggccgcatc75342 cacgatcattaacatcttccagagtcgctttaatactttccaacattcccagaaattttc75402 tacatcttcgtcgaacatttggtcggggtaaatgtgtttcacctgcacatgatctgagag75462 gatagtttttttcttacacccacgcagggcttttttctcatttcctactgcgaccgtact75522 aatgattttacctcccgtaataataataggagtaaaaatctgtgattgttcatgaatcgg75582 ttctcttgttagggagttcaagaataaatcttctaaatcttcttctatgaacttcggcag75642 agtagtaatatgtgcctgcgttagcaccagcgcactactatctacttgatacctaaatcc75702 tgtcgtcgtattgattagatccggggttctaaataacctcagtactttattcctcagaga75762 gacttccccaactcgtatttctagcgtttcggaaacctgcaggccgacaaatattttgca75822 caagatcggtcgtctgatctccacggtaaaattatcaatcaattcatcatgtggagattc75882 tgaaatttcaccaagatgagaagtaaaaatgtattcttcctcctggcggtcaaaaggcat75942 cccattcaaacgattcagttcagtgttaataatcgcacacatggtagggtgtttgatcct76002 aaaaccgaatttggtaatattttttatcggcccgcgagtagagatcgagtagatgcatcc76062 tccatagataatgtagagtcgtccgctgtggtgatctatgtagcgtgcaggagactttga76122 tccgcgcttggagacttcttgaaaagccacttccatttcagtccttctccaaagagcttg76182 cgcgtcaagtgacggtaccgctattggtgctttaaaagtatccgccctttatactgctcc76242 aattctatcgtagcataaagttttgacgatcatacagcgcctgcgtcttggcaccaccta76302 caaccaaacctgagctctccttcaacatgacaactggaaacgaagccaattcaatccgcc76362 tctcttcagtacaagtaccgggaaattgtgagattgacaagctgttggctggatttgact76422 acgaaaaagaacgtgatggtgactattcgacactgaacgaaggatccatatttctaaacg76482 atcgccttatagcttcgggaagtgaagatacatctgatctacaatatacgcgaatgagga76542 aacaaactttttatcctagtttagcccttcttttaaaaatactctgttgtctgcctttct76602 tttggtacgggaattgcacgcgagagaaatatttatttgtaaacgctcttattatcactg76662 ccctctcctgtctagaaggactattgatttccttttttgtgtaccgaaacgtgaaggctg76722 atcgtcttcctttaaaaggtcctgaaaaactcattcaaatggtgttatgtatgataacgg76782 ctatatatggggcgattatcttttcaaggcacctttttgcggacgatgaccttgctattt76842 caatatttgcgaaaaactggacagacacacaggaagccttgagaattggtcattgttatc76902 tctctccgtatttttcgatgtgggctgcctgtctgtactttataattcttctatacgacg76962 ttattgacgtgacacttcctcttttgtgggcctggacaatattaaggacagcaataagct77022 tctaaatcgttttactgctacacgaaatcgcaaagttaggtggaaggatcgcgttactgg77082 cctcataaaccccgccttgaagcctcacccccggtaaagacacgataaaggcagagactg77142 cagtattataacgggctgacttcgtaggataaaggcaacctacaactctgtgtgctcaat77202 atttagccatgaatcctgacaacgggatcccgcataacagtcatcatgatcgcgcagcat77262 tcccaagatctgctgcccctttcgtagcatctggggaactgttaggaattcttcgagaaa77322 attgccatgcgcatctatatgaatggataagccgcgaaggggattgttgctacagacaca77382 gctttgatattctgctgggatcttatttcaatacactaacgctcaccaactttctagaaa77442 ccggactttcagttgcatgtatttgcgtgaaatttccagagttacgctatgcagaccgag77502 gaataatccagtttgtagtggctaatcccatgattgcaagaagtgattgtgaagtacctt77562 ctcggccatcatttacctacatcagtaagagatggtctaggacgacattatcctcatccc77622 ttgtgatttgtgcaccagctctgggcttgctaagtggcgagtcacttgacgggaccgaaa77682 tatctgagttttctagattacaggcgttaaaccaacttgcacgaaacctcaaactaactc77742 tagactcatttgaaagaggaacaataaatcatgtgctgagaattctaatccgaaaagctc77802 caccacttcctcttctacgacccatgatggcggcgttggaatgtgaacgagaaatgtcta77862 cggttgccagagcaaatattatctccagtatgaaggcagccctatgtgaagatttgtttt77922 tcatagataaggagagggggcacgagactccggatttcgcccgaaagctattagccttaa77982 ttaattgcacgcttcctagtgtaaccgatgctcgtgttacacacataggtccggatggtc78042 gacttatagaaggggtgattgttacaaccgaagccgtaaaaggcctcatcgcggcccgcc78102 ttggcatcgaaactgcccgtgccaacgtcccggcaatgtacagtgagatggtattatctg78162 gaaatagccttgtaacggccttactgctggggaaaaccattcgtaactttgatgaagccg78222 ccgcaaatttgttaagctttttggacggtgaaaaaaatctcgccgattttccagaaatac78282 cgtctaataacgcagaccaagttccaacaatgtccgtcaaaatgtccctgctcaacgtgg78342 gggaccatcttgtcagcatagaagcactagagcgtgtttacacgcgcactggagttccct78402 acccactctgtgaaaatgtggatctgacattctttttcccacttgggttgttcaaacctg78462 caatagatcgttattccacatctgagattgctcctgcggtcggagccccggattatcgcc78522 agtttccccctacagaaatgtactttttcaataaggacggcatgatggttaaactcacgt78582 ttgaagactcattgccaaccgtcgcacatcccatagcacatggaatgctggaagctttgg78642 cagaactttgtcaagaaccatgggtttcaaatcgcagacctgctccgatggggttcacaa78702 ttcaacgtatcggactaaacccacctcgcctgttaatgatcgaattcttggaagcggtag78762 cacgtactgcccctgcaccatacccagacgcaactttaatcaatcggaaaaatccagatc78822 aattctctagccataccaacccgttccttccattagaggttcacccgttctatgatgtgt78882 acagagttgcgcaggatctaactattccctgtgatgaaccattgtttttcccagccgaac78942 caataacactggccgcctctaggcgactctgcaacggggatattccgttgccgctgtctt79002 cagtcgattttagacttgccagggggtactgtatcgctgcaggaagacacagactgcacc79062 cttcaacggacgcagccatagaaacaacactatctgatgtgaattacccactggctttct79122 atgtaattgaagcttgcatccatggcgatgaattgattttcatggaatcgcagaggctag79182 tagcgcagtgcatcaatagctattggcatacatcaaggggactagcttttataaacagtt79242 atccaatggtaacgtacatttatcacaacatgactggaatgatcgatcgagattgccact79302 ccagatatgcggatgtaatgggcctgcttcacgcactgagggaaacaatcagaaattata79362 ctctccctgcggaaccaattctcctgcgttctcatgaggaattaaacaatctcatgacgg79422 acccggcactttttccgcccatgatttatgactgtgattccatcctaagggcacgcactg79482 catgcgcgactagaggggttacgatctccaccttcggagagagagcacctaccgtttctg79542 tcagggaatatccagcccaagtggatttcaccgttcttagtaacactctaaatcacggcc79602 cagcatatactgctggcggaagacatgaaggaggaacccatcatgactccgaatggacag79662 tactcagcaaattgttttactatgtttttctacctgctgtctctagagggaggtgttgca79722 gtgcaggagtcgagtttgaaatgatctacgatctcattaacactaccagacttccagata79782 cagttgatgaaatggacaatcaggcaggtgccgtcgacagaggtcctttggcggatgaaa79842 atcttgcccccgaatcctttaacactttgttggcaaatggatccataaatctggtggata79902 atgaagctctggtagcatttatcgctgccgcacggcgccgtcaggcagtacacacgatac79962 ctctgagagttaactatttacctgacccgggcttcgaaactatagacagcccgaggaatt80022 ttttggtagacggagtcttatacaatggaataatcatgatgaactatgctcaatatgacg80082 cgacagctattccatctcgctatttctatgcattgcctgtgaatggattctttatgaacc80142 gtactatcatagaagcatctcacagggctaacgtcaaccttactaatgtacctgaggact80202 tgccactagttcctacatttttggggagcgaagtgtatcgctccataagagcaccgtcgt80262 acctatttgcttcgagagcttcaaactatgcctcaaactcggtcgcggcatacagcttgc80322 tggcaggatacttcaagacgtctcccgtcgcacttgtccatcagttgaaattaaatcttc80382 atccagggtttgctctcactgtcgcccgccaagacagatttgcggcggatcaaattttat80442 ttgcccgaagagcatcggaatcttactatctaggatctccagttgtaaccaaccgcccag80502 agaatgattctctcgtaattgagataagtcagccaagggggcacatagatatgggtctgg80562 gatttacagcgagtcgtgttcctgcaaaaattaatacagtggttacagacatgggcaatc80622 attgccaaaatctcttcaatgcccgctaccctggtcagtttcgccatgcggaagttgcgg80682 attttattgcctctgaaataacagacaatgactctacagccttgcctagagcgcagcctc80742 ccattctgctgtcttacgaaaaggcacccatccccccttgcatagagcggggacagcttg80802 ctacatgtgagtttcttttaactccagtgactgccgatcttgcatatttttatacatcag80862 caaatccccgagggcgcagcagctgtatcgcgtgcaccaactgcgaggatccatgcgcga80922 gtgaaactgaaaaggctatgtatgaccattctaccccagatgcagcacacccgtctaggg80982 ctacgaataatgcttgggcatcgcaaaagtattcagtgggagacaaaatgtataatgcgc81042 ggcggggttttattacggccagtgatttttacagtcctctgagcaagtttatgacgccat81102 ctagagctgaagataagagtcggtgcctggctcgtttgatgagagattcctctgcggcaa81162 ttagttcagttacgggtgacactgagtatcaatttgtcgccccgcccggtgccaacgaat81222 tagtaactgatccgtgcgcaatgtttcaagaagcgttcccacccctttgtagcagtgaca81282 aggtcctcttcgcaacctacgaaggccctaatagagcatctggatctggtgcaagagaaa81342 accactttgcgcagtatttgattcacgataagtctccaatcgccaatgcgttaaaaaccc81402 catgcaacacgcgtcgctaagacggaattcgcaaacgatttctacccgtgaaatcacgtc81462 accgcctggtctgtttgggcggagccctttcaaaacttcttcataagtgtttcctgtgca81522 gatgatttgcccacggagggatatatagcgcatacctaactaaatttcagaggacagaag81582 tacagatcgtatcagccagaacgatgacaagcggacagtacgagatccgcgttgttctgc81642 caaatggactgacacgagatgaagaagatcgtctcagaagcttgcgtgggactattttaa81702 tggcgccaattttgcgaaggtgtgtttttctgcacgaaatcgatcaaaaatcatttttcg81762 cccatggaaaagaaccagactatgcaactctgctcacagcctacaggagacgctttccca81822 tattaatagtttgtgtcgaaaaccgagaattgagcgccatcgcgctatccataggatacc81882 cgcgcggaatcagcgtgcgcaacactggtccatttagtttgaacaacggtgatctcgtgt81942 ctttactgccacccattacgaatacgcgttttcgcgtcgacttgccatcctgcggctctg82002 taatcgagccagccatgacaattcctttcgagatcggaacagaactgatgggaaagattt82062 ttgcagggatggcctatgacttctgcgttagaaatcaaatagcgacaacccgtcctcgtg82122 atatttatgttgtaacatataagaacaagacactcgatctatctacattgcccccgtctg82182 atgcggctgcacttcaagatacaatgaaaagcctattttcatcggttctattttcgatac82242 acgagggggtcatgtccgttttgtcactaatgcctgctttattggcaggaggggcgaacg82302 atccatttctcaatgccattctacaaatgcaaagcatgaccagactttccgtgcagcttt82362 ttaatccacccgcgctagaattaccggaacctgctggcagctctgggcgatatcatgtat82422 ttgatgcttttgccgcgtggctttcaatgtctcaccgacttggtgatttattcaatttga82482 aaccggtcctcaaagtagtaatgttttactcggatgattctaccgcagacgagggagacc82542 tcctcaacgccattgtaccttaacccgtctgtgcatctctatgaaatgacgagacatcat82602 atctctttgatttgtgaataaagtatttattatcgaaattgaatttatgctggtctctgt82662 cttctaccgatcggtgcgatggggtgatatccggcagtcggggaaccttctagtgctaag82722 tatgtagacattacagcggccactaacatgtcatcgggtacgcggccctgcttaccgcta82782 aaagttcgaaaggaatcgggcccttggccatgagtaacagtaatgttccttatttggtct82842 acgagatactcgcatggatctttactgagtacaagggtgttcgagacaagttcctgggaa82902 gccataaagcgcccagagttaaataggctgacaaacaagtcaaatgctctgctcttttgt82962 ttgtttagaagataaaaagggtgagccattgcagttccaggctgccgactgtgggcaaaa83022 gtcagagaaaagcctaacctcctacgcaaagaatccaaaagctctgtcaagttgccggct83082 atggcagcagcagaatcctgactcgaattcccctccaccgctatacgaatttctcgaaat83142 gcgccagcgtgaataagacaacagtatgctatacacaaatacacgcactgggcaatttcc83202 agcgccgcctctccggtcagtgcatccaagtaaaaatgttcagctcccatgagaaccata83262 gagtctcgcagcgcagtcactaatgctatgccagtaccagatgcgcttctgtttgtggta83322 aatgcaggatctacatacacagtgagaattttcccgagcccagagatgttgggtttactt83382 gaggtagatggtctgtaaatcaaaaactgatccaaagctcgcacaggaacaagtgtacga83442 tcggagtcatattttccagcacgtccaccggcaatctcatgcataaacgaatcttttacg83502 aacaaatctgcggtatttcgaacctcgctgtccatactaacaaagactggtttgtgcaaa83562 acataacaagaacaggtagtcacgtctgttcttttctggatttcaggcatgtgttcgtcg83622 catatataggtaacaacattaagcagagagtttgtctttcccttaagattgtacagtaga83682 ctcgtgttactatggcaagtgttggtagaagatacgaagaaaagtttgcagttagtctga83742 ttcaaaaaccccatcaccgtgtggagagcagccggttttataaaatttgcttcatcgacg83802 aacaggaaattgaagtcctgccccctgagaccctgcaaaaacagaccagcaataaaagat83862 cacactcaacggacatgattcattcaccagcgcgtcgcaatggaagtacatgtcttagca83922 gcgacatcgaagctattatcttgcggtgaacaggagggaggtcctgcgccgatactaagt83982 cacctagtcctgtccacgcagtgcttagaaggatttgaagttccggttcaccttcttagt84042 gacaataagttttatacagaaattcaaattcgacaccacggatgttttgactgcacagag84102 tggaaacaagttttctcaacttttgtcggacaccgggcactcgacaaaattctattacct84162 gagttggggaattgtcaagagcgcccctttcgaattacgtatgatggtgggaatgactgg84222 ggaggactgttcatcactatcccggtatattgcgacgcagaaaagatgacatatgatgat84282 tttactgcggtggctatacgaatagctataggagctgcgttggaagaatattatgaactt84342 ctattcacgtatggagagctggtaaactcttctactcgctacaatgtagacagtgccaga84402 ttagaggcgctttcgtgccagctattagagtactctccatcacatttaaatgaagctcaa84462 accaagtattttcgcgatattaaaaaacggctctccgaattactcggcaaaaaccggcaa84522 tatgtaataagcgcagctgaatatctctcaaacaatctacaacgatttgatgcgccaccg84582 gacacgtcagccaaacaggctactataaaagaaaggatagacgagtctacacatctcttg84642 aaacaggtggcaggcgcttccatgctgcccatgaagaagtacacccccgttccccaagga84702 agtgaaaatttgagggcggtggcccaagggttgagcgctctcgtaaaaacgctagggacc84762 cgaggcactgaaaagatagcagatgctcggttttcatcaaatactgcaacatctgaatta84822 gagccaccaggttgcagcagaggtttcgaaaaggcggcaccaccaatgcctgatataaga84882 aatgttatcatgacagacaggcaaaaaaccacaatgtctattacatcaagatcggtaact84942 tattatactatgtatgattgtctggcagcagcctgtgaaatcatggaggcagaaaataat85002 tctaccagaagatcatggtcactcggaaaaatctcaattgtgttgatgtcgtgctataac85062 tctggagctccaatcatggttgtaaattattcccaagactcgttaaagttatgctatcca85122 aaggttagatctggagcttcaatactagctacaataatgagaccgctgggagaaacctca85182 gtacaaaatttaaccgaagcagctcagcaagaaatagtgaagaatgccccatgttttcaa85242 tgtcctttgaaagctttgaaagatccagattctctaactaaattgtttgcagtggactgt85302 gaacagttgctcctttatagtttccaagcgcgcgtggctgcagcattcaccgcagcggtg85362 tccgaggccattgtacgagcaactcacacagagagcaatactactcggctcggacagcta85422 ataaactacgacatccctttataccagccatttgacagcttggaagcaaactggccaaca85482 caaatagcacgtatggcttcagacctaatggcagttctctgtataactcttcaaagtgaa85542 cgcttgtccgtctttatgaaaagtggaatatggcgcgccatcttggcaatgttaattcga85602 aaggaaaatcaccgaagaccatacctggcccctgttcatgtggaggatgacgtgtaccta85662 ttcgattatttcagattcggatcgagtaatattgtaagaattaccacagagcctgttgtg85722 ttaaaggctcgcaaacccaaaatagacggcctctacgaacttgatttcatcgctagtccc85782 ccctctggcctccacccgtggactaaacaaaaattccgcccaggagaatttcactcctat85842 atatgcgttggtttcaattcggccctgaatgctcttctcatctttcctggagggtttgga85902 ttagaatttgattttggcgaagcactaaaagaagtctgggaggatcacctggatcactta85962 gtattgaaacgctttagtaggcgtgcaccatactaccctgaatcttatctcccgagctgc86022 gaattcatgcaaaagataaacacagctgggtagctagaaattgcgccattggcacgtctg86082 caggcattcttgcttaaatgtaatagcgtaggacatagaaagcagttaataccgagtaat86142 taacaattagtggtcaaatggattactgttaggactaggtaaatgtacagaatacttaca86202 ttcgtattttgactggaggcgaagacaatcgcacttttgtttccattgcgaaatgtaaat86262 gtgatcgtttcccccttgacctgttctacctgttttgcgccaaaccatttgtacaggcga86322 gtaaaaatttcaataaaaacgggctctgttgcttttcttaagtgggcagtgtatccaatg86382 cgtattccttcaaaagatgaaaccagtagggaaatgagcggaactaaaaaccacgttttc86442 ccgtgcctccttggaactaaaaatacagtagttctttgtctaaaatgttgaatgatattc86502 tctgaaaataatgaggtattaaaaacggtagacaagtatctattacttcgttccgtggat86562 ccttcccccaagcaaatacttgacgcaaagtatgtagcatgcattaagatcattttttga86622 aataattccagtgttccgtctctctgttcgctagttgttttttccaactttgcccgtttg86682 tagtcatttgaagcttgaccagaaaatgacttttttaacagtgtgtgaaatctgtaaata86742 aagttgttcagttgggaaaattcatcagacttgacaaacccccggtagccattcattatt86802 ccgtcgaatgctttgtcatgtattagggagtcgcttggagcaaacctggcaaaatttaag86862 tttgcgagtttctgtcttagtgccggaaggatactgtcctcggctgcacctgtgaaaagt86922 tgccgtttaggggatacctgtaaatcgtttagtgcggcatcggtatctgtgtacttggta86982 gaataggaggccagattttcgtaaatgatttctgacgccatatatgaaaacgcacgcgaa87042 atagcacagcaattatgaaaagatcctataggggcaatgcacgcttgatggcgctgtgga87102 acatcaatcgcaaattgaaatctgctcgccggtgaattcatggtatccctcgctgaatca87162 ttcctatcacatatacttgcagtagttataaaattggagtcactcatttcttgcccatcc87222 acgtcgtctggtcctcgttccattgttcgcttacgcaaagcatcgcggtatcttttgaca87282 atttcgaccgattcctttccaagcatgtcttctgcgagagactaccgaaacagggctcgg87342 gccgaagttatgaactacattaaagggcaagcctataaagctgcggtcatcgagatgatg87402 tctctcaaagttcctcgaatgcacccagctctgcgctattttcttgcatcagctagggag87462 caggaagctgtttcagagataaacgtgcgctcaaataagcgcctcagctctgtcaggtgt87522 catgttgctcggataaaagcagctacagagagtcagagagcattaagactggagttggat87582 ggctacagaagatatctaaggaacgactttttagaaacattcgctcaagagtcagaagcc87642 attgcagatgcggagctagacttgcagcgggcagaagaagaaattgctctgtatatttca87702 ggtgaccctgatcgcagagacagcttagattgtgaggaagacgaccttttattaaaatgg87762 caactagaaaacgtaaatcctccgacgctactgccatcaccacatgcaccaagtcccgtc87822 agtcgcgggaactcgccaagaactccaccgactcccagtccaacttttcaagaagacgaa87882 tgcccagtagaagaatactaagcaacgatgatggaatcgaccttgagcatatagccccgg87942 tctcagaagatttgacaaaagaatcgagacagcttgcgatctacataatgccgaaaccta88002 acaaaatatgtctcaaggtcaatccaaaaatgagctaccgatggtttaacctagaagggt88062 caacggtaattggaaatggtggatatggatcagtgcagtatgccccaaagtaccacatgg88122 cagtaaaaatatttgaatcggatggtcattttcgatgggaactagcaatgtccttgattc88182 tttccaatgcggcaagaagaccagaactttccgacatcgccaaacatttcttacagatct88242 atgccttttcaaaaatcgagagagcttttgtaatggaaccgttgagccatgacctaaaaa88302 cgtacgccaaaagatacaaagacaattttacaatggaaacattgaataccctgacatctg88362 agttcaaaggacttgcgaaggccttggcatttctgaacattgattgcggattggtacaca88422 tggacgtcaagagtaacaacatactggtcaaatgtgatgcgaatggaaaacttagtcgac88482 ttgtattggcagactttagtttgacaggccctaatactaattctattctcaaccagagca88542 tgatggtgtgtccttcaagaggagtagtggaagggctaaaaattatagattcaacgactg88602 taaagaatcacattccatctgactcttttatcatatataacggccactgccgagctccag88662 aagtgataataaattattgtaatgggaaaaggtatcgcgaccagccaatggacgccctgg88722 aaacacttggattggatctattttcccttgggcaagtagtgcaggaaatcttatttgagg88782 gaattctgtgcagatcgcgcgagttttcgtttaaaccaaaaccaaacactattcatgaaa88842 aattaagtcacgattacatgatgagggttttggcatatcgaattgtgctttccgacaatc88902 taatctctagaggctgtgatctaagtttcaccggtccactaagtggaacagtagaatcag88962 tgaacgcatccctatttcgagaattagacagaatccttttccagagtcacgtcgaaatgt89022 atgagcgcatcgatctacgagaaaaactgctgaacgtcatcattcctccggaaaccagag89082 gactttgtaccctggcgggactgctatgtcactgggatgcggatttgcgccgctctgcag89142 tgaccttcttttagagattgtgatcgttacttataccaataaactttttcagagctttgt89202 attacgtcgtttttttgtgaccggggactctatcaaggggcgtggttgcgcgataatggg89262 gtatattttggcctaatgggtaacaggcagcaaggtgttccgttcactagtcttcatctc89322 gcagaggagaaacatgacaagtgttcaagaccagtctcctctgaacgaaaacatgcaatg89382 ccagaagactttagaattgtcggttggaatgcagattccgaaagaactaccaggagtggc89442 aatgtttacattctacgattacttagccgacctggcacgcggaggacacgcgcaaagtga89502 cattcttcaacaggaaccactacatcaccgcctggcttacatcagccacctgttttcgtg89562 gctcgaaaaagaaggtttcgcgtatggcattttgaacaaattttttggttctgagcgcgc89622 tctgagcgcatcagaaattagtagtaatttatcgcaacaacagatcaatgaaatcttatt89682 tttcatagaatctgaaacgaaacaacaagcgtcgtgtgacctgtggaaagttttaagaca89742 atttttattgacggcttcaactttgaagtggatgaaaaataaaccgtgctcaaagccgga89802 atggtttaaggtacaggaattcaaaggcggacaccttggctatgccacacagtccatgcc89862 tttgatttttggcaatactaacgaaagctgcgcccgatcccttcttttgggatatgtaac89922 tggagaggcatggaaaacttcagaagatcgagaagagttttacaaatttgacgacggcca89982 tccaccagaagaagcatttacatgtggacttcttttagataaacggagtggaatgttggg90042 agcatcaatggatatggcgatagtaaagcgcaggaaacagtgcgctagaaaagtggagat90102 atacgaaattaagtgcagagcaaagtatgtgttctcggtcgagaaccagacgcatccact90162 ttctcaactgtacgataaaatgttgcaacacccatgtgaaaattctattcgcgatttctt90222 gctgggaatttcctcaccgggggtagaatttgttgaagagagcggaatccctacagcatc90282 agaagctctactaacctgcgacaaaacttggaaaactgacaggtggaagaaaaatttacg90342 agaacgtgcttgcctaatggaaaagcgtcacttgtccctgaatagaaccaacaactcatc90402 tgtgtttttgtttgaaagcccctgtctggaaacaaacacgatcagacctgtccagtggcc90462 ggacggtgaaaacaatatcgagttaccaatcttcattaacccaaaacatcagaatttcaa90522 acagatttttgtacagacatacgtcttggccgaatattttgaaacaattcctatatctcc90582 atttttagttacatttataggtcgcaacagaaagacggtagagcggggacgtgtatttaa90642 gctcgaacacacattagacggtatagaagaaccggtggaattgaactgcaagcacgcgat90702 accggtactactaataataacccccacaaccatcgacagaaatcatttcagtgatttgga90762 ctcgcttggcagagaagcgttcgagttttctgtgaaggaaacatgggccaaggtctctgt90822 ggacacctcggagaatgttgctgcccctgctgttcaaagtcctgcgggggtgacacaaga90882 tcccgaaaatctggagagcgcttgtccctattagacgacagctttgacgaattcaccata90942 accgaagacatgcctatgattcaaggaggaaaaaagaaagagaagcgtagcaaaaaagaa91002 gccgaaccaattgtagttgagccagtggctgctagaaggcattgaaacatgttatttcaa91062 ataaacagaactacaaccaaatacatgcgtcaacctttatttgcgttatgcgtaatctaa91122 attacagttcgtcgtcatagggtacagtttcataaacgtgcttgtctcttcggcttttgt91182 atttttcgcggcgcgttttgcgtttcacggttttatctaaagcttctgtggcaacggtcg91242 ttaccttgcggatgaaatccgtctgtctgtactggtgatatctgtatgcccgtacgactc91302 gcagaatagccaaaactaaaacaaggagggcaaatactcctagaattcctgccgcagccg91362 gcttccagttgggatgagttccgctatccaacgtattagcatagtgcagggatgccgtcc91422 caagcattccaagagcaatgatgagtccgaaatgcggaccaataagtacatgcacatact91482 tcgctaaaaccagctcggtcacaatcaagtatatgatacctatgataagaaatgcaatca91542 ttgccccaagtgtagaagcagggacactgactccaaaattcacggtcatgacgagtgctc91602 cggacaaggccattataagcccccaaactcccatgatagaggcgtagacgtttaatacca91662 ctgccttaaacggtgatacaacacaatgaacttcagggcatgcacttttgagctgtgagt91722 taaaaactgagtactggtcaggtgtctttccggaagacgcgaacgtacccaaaaatacga91782 tgccggatacaaaaataatgcaaaatgtgacagctgatagcgtaagctgtctgtacgaaa91842 ggagtagtacaaacaactgccacgcccatactgtgataataatagacattaaggcaggtg91902 tgctgatcacggccgaagtcaattcggacgctccgtatgaacgatcgtgattacaagtct91962 tggctctaactgcgccaagagtaacgtatatcgccaagagtatccacaccgccatagtcg92022 cgtaaacggtaaatatcattcctggcgacgaaataaaaaaaagtccatcttcgttcgccc92082 ttagcagtccaggttgattgatcaaaggcgttgctggcttaaggtgtccaccggcgacgt92142 tgccgaaaaaacagggaaaccctgcttgcggactaagggcggagaaagctgaggccagtg92202 atatcaacaccagaaccacaaaagagattacttcaatcagccacatgcgccatgcaa92259 MetGln tcctctctaaacgcgattcctgtccactatagtagtagccgctca92304 SerSerLeuAsnAlaIleProValHisTyrSerSerSerArgSer 508050855090 ttttctgcgctatgtgaattagcgcctacgtcgctcagcgggagg92349 PheSerAlaLeuCysGluLeuAlaProThrSerLeuSerGlyArg 509551005105 aacgatatgtcgccaaataattttgctcctggagaacaactgtgg92394 AsnAspMetSerProAsnAsnPheAlaProGlyGluGlnLeuTrp 511051155120 ttgtcgcccagcgtcggactcgcacgaagactgtacggatgcgat92439 LeuSerProSerValGlyLeuAlaArgArgLeuTyrGlyCysAsp 512551305135 ctcagcgatcgcctattatccaatccgacaatgagtaggctgagc92484 LeuSerAspArgLeuLeuSerAsnProThrMetSerArgLeuSer 514051455150 ctagatcagcagcatggccatccggttacgttcccacccccctca92529 LeuAspGlnGlnHisGlyHisProValThrPheProProProSer 515551605165 cgctcgcgaccggtgttgattgcgcgcgctccgatgggatccggg92574 ArgSerArgProValLeuIleAlaArgAlaProMetGlySerGly 517051755180 aaaactacggcactgattgaatggttggctggatttctagaccac92619 LysThrThrAlaLeuIleGluTrpLeuAlaGlyPheLeuAspHis 518551905195 caggatagaagcgctatagtcgtgtcatgcagaaaaagctttact92664 GlnAspArgSerAlaIleValValSerCysArgLysSerPheThr 520052055210 aacagtctttgtcgacgattccaacgggatggtttggtgggtttt92709 AsnSerLeuCysArgArgPheGlnArgAspGlyLeuValGlyPhe 521552205225 gctacgtatctagactgcgaaaaatacataatagatgagatttca92754 AlaThrTyrLeuAspCysGluLysTyrIleIleAspGluIleSer 523052355240 caccgacggctattggtacaactggaaagtctgccacgcgtctct92799 HisArgArgLeuLeuValGlnLeuGluSerLeuProArgValSer 524552505255 agtgtactattggatcactatgatgttctagtagttgatgaagta92844 SerValLeuLeuAspHisTyrAspValLeuValValAspGluVal 526052655270 atgtctttgatgaatcaattcttttcgcctacagttagaaaacta92889 MetSerLeuMetAsnGlnPhePheSerProThrValArgLysLeu 527552805285 cgtgaaacggaagctttgttttcattattgttatctaaatgtcag92934 ArgGluThrGluAlaLeuPheSerLeuLeuLeuSerLysCysGln 529052955300 tatatcgtagcgatggacgcaacgataaatgcaactcttgttgaa92979 TyrIleValAlaMetAspAlaThrIleAsnAlaThrLeuValGlu 530553105315 atgctcgcagatttgagaggggcagaaaatatacacgtgatagtg93024 MetLeuAlaAspLeuArgGlyAlaGluAsnIleHisValIleVal 532053255330 aatgatttcgtatcgagcgggtttgccaatcgtcaatgcacaatg93069 AsnAspPheValSerSerGlyPheAlaAsnArgGlnCysThrMet 533553405345 cttaacgcgcttggcgcggcaatacctgccagtttgttaaagccc93114 LeuAsnAlaLeuGlyAlaAlaIleProAlaSerLeuLeuLysPro 535053555360 tcagaaggaaatgaggacaaaggactcgaggataacaaaagtact93159 SerGluGlyAsnGluAspLysGlyLeuGluAspAsnLysSerThr 536553705375 gcacaggtggatccatctctacttgaagggtccttttttcatgaa93204 AlaGlnValAspProSerLeuLeuGluGlySerPhePheHisGlu 538053855390 atgcaggcgcgcttattgcgtggagaaaatatttgtgtcttttcc93249 MetGlnAlaArgLeuLeuArgGlyGluAsnIleCysValPheSer 539554005405 tctacgctatcattttcaaacgtcgttgcgttcttttgttcagaa93294 SerThrLeuSerPheSerAsnValValAlaPhePheCysSerGlu 541054155420 attctaagtcctgggacagttctcttactgaactccaactctccc93339 IleLeuSerProGlyThrValLeuLeuLeuAsnSerAsnSerPro 542554305435 cacgtagatacgactaactgggggcgatttcgagcagtcatctat93384 HisValAspThrThrAsnTrpGlyArgPheArgAlaValIleTyr 544054455450 actacagtggtgacagttggattgagttttgactcttgccacttc93429 ThrThrValValThrValGlyLeuSerPheAspSerCysHisPhe 545554605465 cactcaatgtttgcgttcgtaaagcccacaatccatggacctgac93474 HisSerMetPheAlaPheValLysProThrIleHisGlyProAsp 547054755480 atgatggctgtctatcaagcgatgggtcgggtaagacgtctacta93519 MetMetAlaValTyrGlnAlaMetGlyArgValArgArgLeuLeu 548554905495 catgataagctttttatatatttagatgtttctggggcatggggc93564 HisAspLysLeuPheIleTyrLeuAspValSerGlyAlaTrpGly 550055055510 gcaccaattttcactcccatgattttaaactcggagtttagcact93609 AlaProIlePheThrProMetIleLeuAsnSerGluPheSerThr 551555205525 accccatggccagtagacattacagttccagcagacgccatgtgt93654 ThrProTrpProValAspIleThrValProAlaAspAlaMetCys 553055355540 gtaaaatttaaaaaccgttgcagacagatcaacaatcatcgagac93699 ValLysPheLysAsnArgCysArgGlnIleAsnAsnHisArgAsp 554555505555 ggggtatttacccggttcaaaaataagcattatgtagaaagatgt93744 GlyValPheThrArgPheLysAsnLysHisTyrValGluArgCys 556055655570 acactaaccagtgctaatgacagttttagtctcctacatactctt93789 ThrLeuThrSerAlaAsnAspSerPheSerLeuLeuHisThrLeu 557555805585 ctagtcaataacaaaataaatgtggagataatgagcgttgactcc93834 LeuValAsnAsnLysIleAsnValGluIleMetSerValAspSer 559055955600 tccgatccgaaactggaaaatttgggtcaattcatatctggtctg93879 SerAspProLysLeuGluAsnLeuGlyGlnPheIleSerGlyLeu 560556105615 cgtgcagatagttatcggaatagggctccacttaagcatctgtac93924 ArgAlaAspSerTyrArgAsnArgAlaProLeuLysHisLeuTyr 562056255630 tccgcgttggaaaagtatgaaaagagtcaagatatattttgcctt93969 SerAlaLeuGluLysTyrGluLysSerGlnAspIlePheCysLeu 563556405645 ccatcaaacccaactcctgaggaaacagctttgatgctcatggag94014 ProSerAsnProThrProGluGluThrAlaLeuMetLeuMetGlu 565056555660 agtgaaaatgtaaaccagttcattgctcgtttttttgaacttgac94059 SerGluAsnValAsnGlnPheIleAlaArgPhePheGluLeuAsp 566556705675 cgatcgctagaaaatttcggggaagacttgcaagcctttctgcaa94104 ArgSerLeuGluAsnPheGlyGluAspLeuGlnAlaPheLeuGln 568056855690 cagcttggtgacaaaagcaaaactatagatgcactaattaatgcg94149 GlnLeuGlyAspLysSerLysThrIleAspAlaLeuIleAsnAla 569557005705 gctgttgtggaaacaggatgcacctgcgatgaagatgaatggttt94194 AlaValValGluThrGlyCysThrCysAspGluAspGluTrpPhe 571057155720 cagatcaatacagaggcattgtccaaagatcgagacagtaaactc94239 GlnIleAsnThrGluAlaLeuSerLysAspArgAspSerLysLeu 572557305735 gactcttggatatcatattatctcgatggtccatttgtgtgtcta94284 AspSerTrpIleSerTyrTyrLeuAspGlyProPheValCysLeu 574057455750 agcaacggacgtccggccgtgattgaggtttgtaatgaaaccgaa94329 SerAsnGlyArgProAlaValIleGluValCysAsnGluThrGlu 575557605765 gttaagaatcgtcgaaacctattaagactatgcataaacattgcc94374 ValLysAsnArgArgAsnLeuLeuArgLeuCysIleAsnIleAla 577057755780 aggacgataggctggaaaccttcagccgatccaaacgagactgaa94419 ArgThrIleGlyTrpLysProSerAlaAspProAsnGluThrGlu 578557905795 attgaacttgatgttatcgtgaaggcagtaaatgacgcattgaac94464 IleGluLeuAspValIleValLysAlaValAsnAspAlaLeuAsn 580058055810 gcagggatggggaattgtatgctagaatatcttcggttaaacata94509 AlaGlyMetGlyAsnCysMetLeuGluTyrLeuArgLeuAsnIle 581558205825 acagaaccctcatggttaactggacctataaggaacctccagtgt94554 ThrGluProSerTrpLeuThrGlyProIleArgAsnLeuGlnCys 583058355840 tatcttggagaaaaaaaaatgtctcgccgcgaacggaagacttct94599 TyrLeuGlyGluLysLysMetSerArgArgGluArgLysThrSer 584558505855 gacccactagagatggcagctgtaaagatcttgcgcactctatgg94644 AspProLeuGluMetAlaAlaValLysIleLeuArgThrLeuTrp 586058655870 gcggagttatttgatgtacgggtatttaaaagccaaaagacattt94689 AlaGluLeuPheAspValArgValPheLysSerGlnLysThrPhe 587558805885 cctggtacggcaagggtcaagaacttgcgaaaggaggagctctgt94734 ProGlyThrAlaArgValLysAsnLeuArgLysGluGluLeuCys 589058955900 gctttgctagaccgcattcacgttccctacgatcgcaaggaaacg94779 AlaLeuLeuAspArgIleHisValProTyrAspArgLysGluThr 590559105915 cacaagcaactatatgctaaacttatgtgtcatagagaacagttc94824 HisLysGlnLeuTyrAlaLysLeuMetCysHisArgGluGlnPhe 592059255930 aagggttctcgactaagtttccggactgctgcgtggacccgtttt94869 LysGlySerArgLeuSerPheArgThrAlaAlaTrpThrArgPhe 593559405945 ttaaaaggacggtgcctggaggacttccatttgatgactccaatc94914 LeuLysGlyArgCysLeuGluAspPheHisLeuMetThrProIle 595059555960 tcttcccatcatgtatgatgaaagcatactttatggctacttatgggg94962 SerSerHisHisVal 5965 catctcgatatatacgattgagactaaacaaaatgcgtcaggaaatattacagacatgtg95022 ggtattgtatgaattagctgtccatgattctactaagggtgcccatgaagtactttatgc95082 atccttacagtttgaagaaagcgacctcagtgtggcctcgtggcctcatccagctctgaa95142 tgccagattactgacggacttcgttggggctgtaaagaatttccatcagagggtgtacaa95202 gctgaatgcaaaaacaattaacttcggatggattctctcatgttctacttctagccagat95262 tgctctccgcctggtgacaggaagactacttcatgaaatcaggcgcgccttgactctgcc95322 agaattttattctccttctattttttatgtttgcaaagacagtggattgatcactaaggt95382 ctgcgaggataaatccaagccacgtatggcaactgcatcttacgcagcattgaatgcttc95442 gtctaacttccaagcaaattacattgaacgcaatctgcaagccggacattgttgtgaact95502 gagaaattttggatgggctcgcatacaggcaatctcatctggaaaaattaatccaagaag95562 catgaccgcggaatgggtgtgggctggtggaaagtggattgatggaagaggaaatgaagc95622 attttctgaaacagggactgatcccacttccgacgatggccttgctgtcccctttgcctt95682 aacacccgcgaaaacaatttatggaccgacgtggtttgttcccagacgcatgcttgtagc95742 gtcattggtgcccaaggagttcgaatatgccatctatctcaaggatggaagtacgataat95802 ctctttagtgtgcgcaataataaatctgtattgcagattttaccaaggaaacattgttgc95862 acaatctacatttctcaaacctattatcctttttctatttccgacaagttcttcccgaat95922 ggacggctcagagaaggtttcatctataaaagactcctacatgtatacacctggattccc95982 gagtataaattttgttcccattacgacgcagaacatgtcaaagatgggagccttgaatgc96042 atgcagaatagtctctcttgtggaggggttatggccagcctataatatcagagcattact96102 catgctggatcgcggagatcgagcgaaacatgggtctcagatcacaacactacccagaga96162 cctcgagagcactttagaagtgtacccagccggtaaaatatccaccatagccgatctccc96222 gactgttatcagtggcaggattttaaaaatggacttttctgctttctttccatgtttgta96282 catggcatgtggcggaggcagccaagcgctatgccgcattatcgaggcaagattaaacag96342 ggagccgcagtcagagaagcttaaagctgccttggtagctctggtgggtgggctaaaata96402 tacagatccatcgaaatataaattagtaatagcgctctgcaacagcattgcattggctgt96462 cgaaaatgctgccaatagcctccagtttggaatagctatttatatgaaggatggattcat96522 aggagcttttgataaacattcctctacaagcgcagaggaactgagaagcaaatgcgaatg96582 ggccgccattgaagaattgcagaagattcttctagaatgcggccaagcaattacaggaat96642 gccgactctgaaactaaggctagagggagaatttacagagggcctgcttcttaattgcaa96702 caagtattggctccacaacaggaataccggaaagagtttcatatgtgggatacctgggct96762 tcgagaagagaatgggctgagtgtgttaacagaacgtacagcttgtgaactgctcgctgg96822 catttacactgccaacaccgtaagcaccgctaccgaaacactcacgcgaattctagatgg96882 atatgccttctctgccttcgaagctagaggtgacataaacttctggcaagagacgctaaa96942 aagtagctttaccccatgcatttcagattccgcagccatcagatctgccagtttcatgac97002 acgcccagatgagctggaaggagagactcactttgtttaccttactccgacaaatttgtc97062 ctcccatggctccgccaacgctggcggtaaagttatctacccaagttctctcgcagaaga97122 gaatttctgcattaaaatatgttattcggctcacctaatccccaaaatgtcagcaatggt97182 ggagcttgtacagaatatggtgtggttaaaattttatcataattctgtggacaatgatga97242 ggagacacggggtaagttattgaaaacgtgtgactacgattacgagagaacatctttttt97302 attctcataattaaacagaacatttccaaagaccatgatacttggtacttcgtcatt97359 tcaaaaataggtatcatataacttatatgcactgcgatgaagctt97404 SerLysIleGlyIleIleLeuIleCysThrAlaMetLysLeu 597059755980 gcggtcattccaccacaatcttaatacgcgagtaaaaaagtttcc97449 AlaValIleProProGlnSerTyrAlaSerLysLysValSer 598559905995 gttgccatatacccgattcaaagttgaattccttgactctaagatgat97497 ValAlaIleTyrProIleGlnSerIleProLeuAspAsp 60006005 ggctcgttcattttcattggaaggcaggttcatgatcataagtgc97542 GlySerPheIlePheIleGlyArgGlnValHisAspHisLysCys 601060156020 gtgggtagaataaagagaagatattagctcttctccaattggagc97587 ValGlyArgIleLysArgArgTyrLeuPheSerAsnTrpSer 602560306035 ggtaatttgcatgaggggctgcgccactcgataatgaggcaatac97632 GlyAsnLeuHisGluGlyLeuArgHisSerIleMetArgGlnTyr 604060456050 caacccgggatcaaagggaggaagatcatgcattaatagcaatgt97677 GlnProGlyIleLysGlyArgLysIleMetHisGlnCys 605560606065 atttaagagccactcccctccattcaccaatagctcgcgcacctt97722 IleGluProLeuProSerIleHisGlnLeuAlaHisLeu 60706075 atcattgattgaaatagttcgcgcgaaacgggcaattgcgcttcg97767 IleIleAspAsnSerSerArgGluThrGlyAsnCysAlaSer 608060856090 taacttatagcagtgttcttgagtaaccttaatggggtcaatgtt97812 LeuIleAlaValPheLeuSerAsnLeuAsnGlyValAsnVal 609561006105 ttccaaatacatgcaaatcaaacagagcgcaaagtcttcaaattt97857 PheGlnIleHisAlaAsnGlnThrGluArgLysValPheLysPhe 611061156120 ttggggcataattctgtgaatcctgtttaaaaaatcaggccatgt97902 LeuGlyHisAsnSerValAsnProValLysIleArgProCys 612561306135 aacatgcacagtggcaacgcggtcctctgaggctgtgattactga97947 AsnMetHisSerGlyAsnAlaValLeuGlyCysAspTyr 61406145 aaatataaagccagcatgatcatctaggcgcacacacgcgcaaaa97992 LysTyrLysAlaSerMetIleIleAlaHisThrArgAlaLys 615061556160 gtactcttcaatatccactactgctccagaaatcagctctaggat98037 ValLeuPheAsnIleHisTyrCysSerArgAsnGlnLeuAsp 616561706175 aattttttccccatccatctggatgtccatatatgttatggaatc98082 AsnPhePheProIleHisLeuAspValHisIleCysTyrGlyIle 618061856190 agacgcaaacaatgctggcgcccctggcgtggatcgtacttcaaa98127 ArgArgLysGlnCysTrpArgProTrpArgGlySerTyrPheLys 619562006205 aaaaaatctcgggatagcctgccgcgatatttccttaattaactg98172 LysLysSerArgAspSerLeuProArgTyrPheLeuAsnLeu 621062156220 tgatgtcgattctccagaggaggccagacgttcaagttcctcaag98217 CysArgPheSerArgGlyGlyGlnThrPheLysPheLeuLys 622562306235 ggtagggccgtgttcgggttcttctgcgatgtcttccaatcgtat98262 GlyArgAlaValPheGlyPhePheCysAspValPheGlnSerTyr 624062456250 aggtcctacttttttctgatgccggcatatcgcgttgaatgcttc98307 ArgSerTyrPhePheLeuMetProAlaTyrArgValGluCysPhe 625562606265 ttcggcccatgatactaactttcgagtcggccgattctctgtcgctgc98355 PheGlyProTyrLeuSerSerArgProIleLeuCysArgCys 62706275 ctctagaataggctctcctgtctctttcagctcttccatcccatc98400 LeuAsnArgLeuSerCysLeuPheGlnLeuPheHisProIle 628062856290 gttcatcttgccgattggcgcacgaacgtctgacatttgctatgta98446 ValHisLeuAlaAspTrpArgThrAsnValHis 62956300 acgtacgttcagatctttcaaatacgaacctacccgcgagctggcaaataatgtttgaca98506 caactcctcctctgacttatatgtagtctggctcgatacaaggaatcctagacgtgacgc98566 cttcagaactttgtgaaaaaatggaccgacaataagcgtgattgcgctagtactgtacga98626 caaagatacttcctcgccttgattattcatatttctttgaattttaaacacgcgcagtaa98686 ttcttgttcccagagcgccgacaatcgagtctcctcctccagataaggaggaatgtaccg98746 cgccagaaaactattagcaatatactgttggtcattcatgtccttacttacatcaacgag98806 gttatatgataaattctcagggagcttcgatagcgactctagagtttctttgcactccca98866 agcctcttcgatacctccaagggtctcccatgctgggcaacggtcatagtttgcttgggt98926 gcgctcagtccgcctggcagattccattctagcctcaaccaattcttttttcattttccc98986 attactatagaccaagtttttattgctttccttgagatcagagacagtcttgaacaaagt99046 atttactacctttccaacacttgtattaacggcagctcgcacagcattccccatgcgatc99106 ttctgcattatcaatgggccgctgcccctgcgctgccgctcttccgccacacccaacacg99166 ggtagggtcaagcacgagttgtctctcgatgttagaaacattttcacgcaagtaagagtc99226 cactacgtctgccacatcaccaactttgcgcatattttgaatatcaataatgaacttgat99286 cagcctagctgctgcagatgtaccggcctcttccacaccttctcccagagccttatccac99346 cacttttgttacatgatctggatcctgtgcattctcagttcgtagaccaagcaaaacctt99406 gatcggagcggtatttactaattgacacaattttgcatgctcgcgcatagcctgagcttt99466 gagaacaggaccgtgcaatcgttgcataggagaatcaaataatactcccctgtcagttac99526 caatggttcccaaacaaccatacattccccaagctccccagtatttccatcataggcgcg99586 gatttcactggttttaacgttcattattattagtgttcgctcatactctaaaatatgtac99646 tgcccctaatacagcacggagatacttcagcatttcgaaccctctggcaaaaagtgaagg99706 cgcgacatgtaggtggtggtgtatttcagtcgttgtactttccaggtcttcatttccgag99766 atcactgccagtggggcgcttttcttgaggttttctttctcgtaccaaaggaaccatacc99826 cagacatgttatccaatctatataacgtacgtaggaaggagccttcccagcttcgcttaa99886 cccgcgcaagcttaactcagacacgccccgtacaaaatcaagtaacactgtctgcaataa99946 aaaggaccacaactcgaacgcctgctctgcaactcgaattccatcttccgaattgtgaca100006 gtaacgtgctgccagttcatccggtgtcaaccctcttgttctgatgtgagtgtcccaatc100066 gcgctccacatcctcaaatcgacagccatccaatatattgcggagaaccgccacttgaat100126 ttgtctaacaacagattctgttgctcggaccgagttatacacgccttgtccagaagtgta100186 cgtcgatgcgcccaggagaatttccctgaatcccatcgtgcgctttgttggatggattat100246 tatccagtcatcaggctcgcctgttagaatcggctccaagaccgcgataaggttgtcgat100306 atcaaaggcacaaggtacctgacgcaattgggaaaatggcatgtccattttcggggaaga100366 gcaggcgggaaatagaaatcaccactcctgtttacttaaatttttcggcaatgcagagca100426 ttcaggcgattttatcggacattacaatcctatcagaacaagctgttcatgaagactcca100486 agccgcaactgtcttggtttgagactgtggcacgtttagatgaaccgaccactttgcctc100546 tggcggaattaccatttaatgtttatctaatcaccggtaacgccggctcaggaaaaagta100606 cttgcattcaaactcttaatgaaacattgaattgcatcgttactggctcaacgcgcatag100666 ctgctcttaatatcttcaataagctatctgcctcttacacctcttgtcccattcatacta100726 tttttcaaaactttggcttcaaaggaaacaacgtacaggctgtgctaggacgattcaagt100786 ttgaaaaacctcacgaacaacgttcgttggcagaacatcaaatggccgacatttattatt100846 attgggacgtgataaaggacattactgcacgcgccatagacacggcatctccggtagctt100906 tgtctgtccttcaaacactccagcagaaaacttcacgcaaatttgtaaaccttgcacctt100966 tcctaatttcctctatgcctccatttgtcaaaagcaacattatccttgttgatgaggctg101026 gagttttagggaaacatatattgactgcaatagtatattcgtggtggctcatgaatgcat101086 tgtggaaaacgcctatgtatcaggacgggaagaagccagtgatcgtgtgcattggctccc101146 ctacacagacagacgcaatggaaagcagcttcgagcacagaaatcaacgacaccttatat101206 ccagcagcataaacattttaagtaatcttatttgtactcctacactgttttcagtcctga101266 atatcaagaagcagtgggccatctttattaataataaacgatgctcggagcctgctttcg101326 gagaagtattaaaggcatttgaatttgggttacctttgacagaacgccatgccagattct101386 tagatcagttcattgtatcagaatcattcatcaaagatccatcaaagcttcctggatgga101446 ctaggcttttctcgtcccacgaagaagttaaagaatacgtttctaaattgcacgcaaagc101506 ttcgtgcacagaaatctgaaaaatatagggtatttctcctgccgatgtatacaatagtag101566 atatggcggcatttgaaaagtataaatccctgacgggtcaagagacactaaatattgatc101626 gctggctgcaaaacaattcctctcgccttggaaactattcacagagcagggatctagatg101686 tgaccgcgcccagatttgaataccatcgagatgagagtaatgaatatacactagtaacga101746 ctgatgcctcgcacgtactcaatagccagatcacggtaacaaaaaaggtaaaaaaattga101806 tcttcggttttgagggaacatttgaaaaattcgcacatgtattatccgaagatagctttc101866 tcaagacgtatggagaagacaaagtagaatttgcctatcactttctgtcgaccttgctat101926 actatgggatgattaaattttacgaatttctccgaacagagggcctccccgaagataaat101986 taacaatggcgtatgacaggttgtactccctagcaatgccggagccagaaactcagaact102046 ttgacatgggaaatggtgaaaaattttgttttaacgaagatgaatgtccgaatgccgatg102106 tgaatgacaaagatgatttattcgatatttttgataagtcgttagatcaattctatctaa102166 attatgagatttgcgggagcgatgtccacggtcaagaaatatttagttatttcgagcaga102226 tgaaaagaatttatactttacgttacgcggtgctgtgtgagctctttgggagtgtattta102286 ctgccgccccctttagctcattcgtcggaacggcttctttctcaagtcaagaaatttcta102346 tctccagtttcaagggagcagtatgtgcatttgctgctcaaaccgacacatataccttac102406 gcgggattacgcgagcaagatttccgggatatgctgaggacacctcaaaagcccacgaat102466 gggccgagccaattttacaaatgctagacttgccaagacttgtcgtaagggatcaaatgg102526 ggttcgtttcagtcctgtgccataacaaagcaacttttgtcgataatataggtggacagg102586 aattaaggatggccataacaattgaccacggaataagttcgagccttgcaatgacgatca102646 cacgatctcaagggttaagtttagacagggtagcaatatgtttttctcacggaacaatga102706 aattaaatactgcatacgtagcaatgtctagagtaacgagtagcgaatatttgcgcatga102766 acttaaaccccctgcgaacgaaatacgaagatactcgacaagtaagccaacacattcttc102826 gcgcgctcagatgcaaagaaacgcgactagtatactaatcctcaaaagtagccacacgca102886 tggctttaaaatcagtttcccaccgtcgtttggagtgttgcataccctcctcgtcccgag102946 aacatgattttcataagctacgtaatggtaggagtccaaggcttggggcatggctcggcc103006 accgaatacgaacaagtagtatactcatgcgatggaggaatgcggtttatttgcatcgga103066 aataaaatgtatcgccaccaattaccacccgggaaagtaatagtaattcacaatcccgtc103126 gcaacaatgatcgctgtagactgtgaagaagaattttgcgcatactgtttggagcgcaat103186 ggttctcaccgaggaccctcaggagaaacattagcttttcagttctcggcatgttggttt103246 ctagggcgcggaggaacgcgagaacggtggagcagcggcaacatcaccatgatgaatttt103306 ttgggcgtcgctcacttaactgtaaccatatacgaaaccccggaagatctagcatctagc103366 gcgcacaccacccccacatgttcccaatcctctccagaatcgctggagtgtccagaggaa103426 agcgttcctcgagatcttgtagagtttgcggcaaggcatgccggactgttagaggaataa103486 ataaaagtaataaacaccaaattatgaaatacgagcatttaattattgcgtcgcattgcg103546 gaaatgagttgaccttcatagttgctgtcacttagctgcagctggaggtagtagtgagga103606 aaatcgggtctcgaaatgtctagagggtagctcaggcaacttttccgacttcggtagaaa103666 gcaatatccattaccctgtaacgcagccgtccgtgccgaagagcacctggagttcttccg103726 tggaggctggcgagacatgcgggcaaagtccatatcagttgcaatagcagcctgaccgta103786 cttcatagtccaggaagtgcaatattcgcgttctgagtaactttcgcaatggggcaggta103846 taaatgttctagcgctgggttccacccagaggcgcacccacgtaagtcaacacgccattc103906 ctccagtcatatgcctggccaatctgcgacaggcatgggcaagattgtcgcgtggaataa103966 ataccggggcatgggctacaaactcgtgaaagaaaactggcacaccggggtgagtttctc104026 catcctcggactgcgtaaaatattttcttgactttcttgacgaaataatgtcttttaggc104086 gagcccttatttgcggggcatgtcttctcttgcaaaagagaaacatctgcaaacttttct104146 gatgtctatttgcacctgcaaatgcggacgtcttagtacatgccatcggaactctgtcta104206 gggaagtacaaatgtcttttcgaatgttatcggtaagctgtcttctcccgagttccccga104266 atgaaaatatcatgaaaacactgtcaaagccacacgagtccaaagattctacatcttcgg104326 tgttattcgttttgacatgcccttggacggctacgtcttttgcgtggtccggagtaacat104386 gagaatgcgtatcatgacattcgtacgatccggaaacacagtcaatagacgaggctccat104446 atagaacttctgtcacagaggggatctcggtacccatatcagagaccacacgccaccaca104506 gagaaaggtcttcaatttattgtttatctcgcaattttacatatattttaacagcaacaa104566 gctccgccccaaaataaacaccggcggaaaaaacatactaatctaaattccagtcaatcg104626 gtgacaggcccttagattcgaagtattgatttgcttcctcgaaatggcgacagttgaacg104686 gacgtcgcgtgcaggtagaaggatggatgaactccaactttaaatgatttttaggcacgc104746 ggggaataaatcgtctagcttcttggccccaaagcatcaacaccgtagatgacaactttt104806 ctagtagcgatgagatcactccctttgtaaatttgtcccagccgatggttgagtgcgatc104866 taggaaaaccttgttccaccgtcaagtatttgttcaaaagcaatactcccttcctggccc104926 aagattctagacacccgtgagtttcctttggaatagatgggtaacagtcgcgtagagctt104986 ccaaaatgcggcgcaagctgggcggtatacggcaccccctagggacactgaaagctaagc105046 catgcgcgtgtccttccgtgggatacgggtcttgcccaacgataataacacgcacatctt105106 gcggattgcagtatcttgtccatgcaaaaatatctcctttaggaggaaagattttgcgga105166 atctagaacagtaggagtactgtaacagcgtctcaccgaaatcttcattttcaattagag105226 gtttcagaattgactcccatgatgatggtattgaaaactctatggccacgtcggtccact105286 ccggtacgagcttcctcgcggatggtataaccaattggacggaagtcatgctcggagggg105346 ggagagtacggcgttttttagcagcgttggggtcggtatctctttggttgctttcagtag105406 gagagctaatgtccagcggacgcttgaagggactttttatgggctgctcgcatagtccgg105466 gtgatagtggttgatgttcgtttccggccatctgaaatttatggtggtccttttatacaa105526 cgaatcaacaagtccacgagccaagacgttagcagccgcaagcccggtagcttccagccg105586 gtcttgaagaagtctaatccccaagtacggattcacttttgcagcgtacccattcttata105646 gtagaaaacaacttccgtgtttacgcacagaggtctgtaaataatcacagtcaaattttc105706 aaagtagtctcccgatggcaacggcccgaaaattcgcgcaccgttatctcgcgaattact105766 atcacatggtgcggccgcggcagaaacaggatcacgaaaaatgccaggtatatcgacact105826 tgaacatagcataagagatgctattagaaaaaaacaagtcaacattttaaaaatcattat105886 catatggagacctaggtctccgttcacgatccgtgttacgtcgacgagcagatggaactc105946 tttgcgcccgacttctaaatggatcgtcgtcagaatctgagtcgtccgaatacaaatgta106006 gtggtctacaggaaccagtaggtactctttgtggcggacttttgaatggatcgtcgtccg106066 aatcagagtcgtcccaatataaatatgacggcctagatggagtacttcggctctgtagtc106126 ctgaaggaccttcacctgcgtcatcgtttcgcatgcggaggctccgattctgcatggaat106186 cgaggtctaaaatacctctgtctgcggcgacgggggattcgggttcattctttatccccc106246 catgacgagtctgtgtaccagtcgtattttgccctgcgccatcataattagacgaggggt106306 ggtggggcgaaagctgtggaggggagcgtctagatggcgaggggagggatgataacctga106366 ggtctagggccgtaggagatggcgcagaaaataaagggggtatagaggacggacgtgcgg106426 gcggtggactatgagcggggctattttctatttcatgccgcacgacccgtcgcacccacg106486 acatctcatatacatctcgcacttctgctctactcgcaaggccatagttgccttccccct106546 cttctgtctccggtaacataaacgtatcggatacggtggtcggccgctttttaaccattg106606 gatgtgcgagcccaactggcttgacgtccgtgctgtcatgagactcgcctttgacaggaa106666 ggcggatcgacaccatcccggcggaatttttaaaatatttcaaatccaccgtgagtggtc106726 tggtcagcatgtcgggctgtatcgtctcaggaatggccattcctaccctgtactctagac106786 ccgatgcactctgtaccgtcggggtttgttcgtacgccaaaaagctatcatatccgctag106846 ggtgattcgtcgtaaactcacgtatccatccattgatcctggttagaaacgagtaaaata106906 cttcaagcatctgttcttcatcctggaatggcaattccactgcgcgtagtgcggaatttg106966 ctccgcgcgtcaccagatgacgcgcgtttgagatttctggagctgaggcgattgccatac107026 tataaacgacacttttagccctcagtagagtagaatacagcgcctcaaaatttctccacg107086 ttagttgacgagttacaaacgtttcaagcattatcgccctcaaaacgactacaacgtcat107146 ctatgggggatagccttccggtatggtgtcttcgagttactggtctttcctgttccaaaa107206 tagtctggatggcttggcgttctccatcggtaataggggtaccggcctgccgcctggttt107266 gaagtaatctcctaacgctttcaactgttgtcggaaaataagctacaacagaaaccaaac107326 cattaatcctcgtacctcaaaaaatcttacacgcgtcatcccaccccacaaaccacttac107386 gcctcatcaagacccagaaatccatatagtgcgcttcatcgatgtccgccacgaatgcta107446 tattgaaatctccgttcattgtcattcttgcgcgcgattctttactctctccagatcact107506 aacgcgctcgccgttgcactggaaagaatatccgtgcagctccgacgcacgtccttatta107566 gcccccgcgcggatacacatgcgcgacgtaacggtatatccgagttttcggattagttcg107626 gtagcggcacactcacccacttactaatcaaataaacacaccgtacgcgccaaaataata107686 aacattcgtttattgatactttgtcagtctataaatcaggtccgtcgatggatctggatc107746 ggttcctagacctggaccttaactggtatctatccctgcccctgtgaggcccaattcttc107806 tatcgtccaaacctacattgcgtaatatttcacgcgccctgcggacacgaattaaaaata107866 cgcgcgggtccgtcgggcgttgcatggggttgttgttttctccttcatccgcgctcaaat107926 cagattctgagctcaatacgatagtctctattggttcctccctccgttgggggtcgcggg107986 gttcaacctcacgcacatcagccagcggctgcgggctctcggccctcccgccctgtcccc108046 ctccatgccaaccctccaccatttccggcggtgggtcgtactcagagtaattgccgtctg108106 aatcatttgattcggaactaagctgctcatcttcggctccaaatggggcatcgtctgcgt108166 cttccatcagcgcttcttgtactgcagcgtcgttcattgagtcatcgctatcgttttcac108226 ttgtggacagtcgggcatcctcactggaggaggagtgccggtagtggaccacaaattcat108286 tatctacaggtgctcggagacgccagctctctgactgtggtatagccacactcacgttga108346 cgggacgtacagagcttaccagggggtccccagcatctcggacaggcagcttaattgtca108406 cctctcccacagagttcttaaatgcggcttccctgcgcgacttatagcgctccggagctg108466 caggtcgcaccctcacaagcgtgtcttttttgggcatctttctagggttgacgtaatacc108526 tcatctcattttcctggatatttgtgcgatgctccaaatagcctatgtcagctttgtgac108586 cgcgtcgattagttctactcttgaacttacgacaccacctaatggagtgtcgcaggaatt108646 gtaggaaatcctctgccatcgactctgggtcacgtactgggagaggaaatcgtaggaaaa108706 tttcgtatgcgcccccgtacaccttttccgttaggagctcgggctgatttgtacgtgtca108766 tgatatcatatactacctccttaagtcgtacaaaagcctttagtatgtacagaatgtgct108826 ttatcgtcaatttgtgcagcaatagcatctccatcgtggcggctttcactaccatcaggt108886 attcgtctacaggagacatgcgacccgactggtgtcgtctgatgacggtgcgttcgttgt108946 ccagcacatgctgaattgcactgtggtcggatgcagagatcttacgcccctcttccggat109006 tttcatgtctcgctcggacctcccctagcttccccaactgttttacgtcatgcattctgg109066 taggaaagagcgctagcaaaaagaaacacaaaaacaatagtatggtggtgtctcacattt109126 gcccatgtccactcaggcacccactacccatccacatcactcgcccaagtttcccttccc109186 gcccggctcttacgttcttctatctccagtatgcgttccgttaactggggcgtcaactcg109246 agttctaccgtcaaatctttctgcacgcgactaagattttcctcgtcacccattcgcgcg109306 aaatttatcgccatgccccgccgggccgctgccatttcaacgaacgggcccgatggcgct109366 gtgggaagagcaactcccgacgcgtcgcagcgatctaccgtctattgcaacgaggtgctc109426 gatgcgctgcttcttaatgacttgcccatcgccgctgcccgctctgtactacctttcttt109486 cattttttccgccacgcgaaagtgaccattgatgtactgcattgcgtcgcggaagcgcat109546 gcagtgccgcgcgcgaggggtttcgaatagctccacagccccgtcgtcggcaataaaccc109606 gggggggtgttttgcgggggggggctatatatgagcagccaaggatgcagggtgtgtgca109666 ctggtggtccgcggttttctccgacccgtcccctcccagtcccctgagtgctccccgccc109726 ttccaatcccttgtggtttcatgtccgacccctactattagatgctggacaggttctggg109786 gttgcgagatacttgacggcccgacatcaaacgccagcgtccgccaacccccccccccaa109846 gttcttccacccgtggagagcaaacggtcagcgcgggcagccgtgaaactagttctacta109906 gattttccagtttagccttttccggagctgaaaaggttcaggtgggcaccggtgggctcc109966 gactggacctcgaagcgcgatcacagaatcgtcacgcagttcgccccgtttgtaagtttc110026 gcggcagcgcgaggtgctttgctcagtagtcatacaggtcacgcccgtggttcttgcaca110086 ataagcgccacactggaattttcgatttccagcaacgctcactggcaagaacggacacga110146 acgtgaaggccccgggggggggggtcttattccgtataaccgcctcactatgtggccacg110206 gccggttaccgcgagttataatagtcaaggattgaaagaagacagagcggttgggtagct110266 gacagttgtcaggccgaaggtaatacgcgctatcgatgtgaaagctatccgggtaacgac110326 accttggcctaaggccgcaattaggtgctactcaggttaagcacttagctaagcgcagta110386 gcacctaactgtgcccgcacttatctttgtagagtgtcgcggaagcaccgtgctcccagt110446 ttctggtattcgtaagcacgtgctgtgagtctcagaggtttcaaaaattctcgttctggt110506 aagttgttcacgcgcaacccacggcgggaaaattttctgctcttgcaagggctctagtgt110566 agccgcttccgggtatagtgggggctagggctttcccgccacgtaaagctatataaatgg110626 tggcagtgtatccttagggaagaacccagagggagaactaggggagaagtttcgcggcgg110686 cggttgcgcgcggtgggaatgcctggcaagtcgaagcctccattgtccgccgcactggcg110746 ttactggtgttactacttggagtcggggatgctcgcagtatacgcgcggcacccttgaag110806 ttactggcggagagcatcagaatactgcaccgtgtgcagaaggacgtaaggcaactcatt110866 ctcgttggaccatgctgacatgcctgcacggtctttgtaactatgtacggctattcagtc110926 tatgttcacgttcataactgtaggctctctcgtttccttataagggttcctgcgacggta110986 gaagagttccgaacatctttacgtccgacacggtgagtaaaagccagctcatttgtcaca111046 tgttctcaacggcaatgccctggaggccggccgcgcgctagccccagattaaaaatgtag111106 attttttgcttaggtctaccctgcccaataatctgctcggcggtttattaacgaatcttg111166 cttttcctgcagcgtctaaacgaaactgaagagttgtgccaatccctttcggtcattttg111226 aaacaccaacagtgtcacaaaaaactgcaggggctctacgtcaatttgtattacgtgctg111286 aattctgtcagtaatggcggtagctctcgcaaggtaagataatggcagcatcgcgcattc111346 tgtactttgaagagactatctaacgcgcagcacagtatctccgagacatcttttgtctcc111406 gtgctcacgcggtccttattggtcgcatgacgagtctaacattgtatctcctatttatta111466 caggcaccgtgccctataacagtggaggattcgtatttgatgaagtcgttcctgaatgac111526 ctggcgaacgccctacagagacgttacgtccgtcagagcaggcaatactagacaatctag111586 tattttgattgcgatttttatatcggcgcttgcaatagtaataatgctgccggccagcat111646 tacaagcttccgtggatcttatgtatcaaaatgaacgaattaaatattcaagtgcattac111706 ttaacacctcgttccgcctcctcccgatattcgtacttgcccccattctcgtcccttttc111766 taatatcactccatggccgcacgggtagaatgttcagcaaagctaaagtcaacggggcta111826 gatcatttccccggtctttttctacaagtcgtcggtggctgacaagctccgactagcaaa111886 agaatgagcacgcaaccagaagtaaattgtacaaaaagttttaataagttaagttaataa111946 cggaaaccacggttaccaccaagggtcagtgacagtgggatgcggtagagggtagttagt112006 catgcgtctatggcgttgacgcgaccgcctatcctctgaagagtctaatctgggtacaag112066 ggttctagtttcccccctccctgaggagacggttagccttgggcgcctggtgcgcgtgtg112126 tccggtgcatctgggtgactctggcgttgctccccgcggagcactccagcaacaacacat112186 tggggaccgattgcggggagtgtgataatgggaatagtcgtcaccaagtagcaatgcgag112246 aggggcgggatttctggcacgcataagcgctagtccttccacgtgaagcgggttccgacg112306 cgcccgcgcccctggcgcatccgggtaataatcggagatgatgcggagaacttcctgtgg112366 aattttgctgggatcggaccaggacgctgcgagagggagggcgggaattaccgtgtcccc112426 cccccacgcagcgacggccctaaaggaagcagaagtgcctcccacaatatcagcacaggg112486 agtgcgcacgcggtagtcccggccacggtacacgcggtcccgaatcgggaggcgctggcg112546 gccgcgccgctttccacctccggcgcgctcacgatcttctttctcgttcttctcgtcccc112606 gtcttcttcagatgagctggagtctgaagaagacgacgacgaggagcatgaggaagagga112666 agacgacgaagaagaatgcatagtggaactggactcggaaaggtccggacatggcggcat112726 cgccccggcgcccacatggggctgggccatgtacggatacaagacggctgaagcttttcc112786 gatttcggagtggctccacccggcatccatggcacgagcaacgtcgcgtaatctcctgag112846 agttacgtgagtgaggaaggggtgcttaacgggaggacacttctctctgtctcctgtacc112906 ctcatcgtcgttgtcggtcttcccaacgctgaggggccatgagacagtgagtcgcctgtc112966 cattactacgtgacctacattgagcccaccccgttccaaccgttcggccgccggaccggt113026 aaacagttttacaaggtaagcgtgcgacggggggctagtccgggcatagacaacacccct113086 ccgcccggtaggtatgcgcggacccgagcgggaatcctcgtccccgggatccctagcatc113146 tacgaccacgcatgcgcgcccagatgtactgagagcgcgctcaagcatccattctaccgc113206 cccggcgtatccaaggtctgtcgtacagagaatggccacgctgcggcccgggtctttctc113266 gtcgggagggatatagggatactccccgcgtgtccacgattctggccaacaggcaccgcc113326 cggcatgcaggcacgtccgcagagggccgcgtaggcgtacgcgcgttctaaaaattcgcc113386 cggggcacgttctgagacaagaatgatgaggtcatagattttgtcagccggatgtcgcaa113446 cgtccaggaaagccgctcctctaagacgcagcgcccccctctgttcacgggtgaaatcct113506 cttgcaaaactcccccagggctactgggtccctcgcaaaagcaggtagccaatctgcggg113566 tccggtcgcggaatagcttcccgccggaccgctgctcaacccgcgcaaatagttcgcgag113626 ccgctccaaagcaggacgcgcgcgatgggcgggcacgtatggctcccctgcggagagcgc113686 aacgcccaagtttttgccatggggacggtaaacatccccttggttcgggatgaaaccctc113746 cggtgcgaacaggatggtagggctgattggggtagaatgaaacagggcctcacctatctc113806 ggaaatgtgaaaggacggggattgtggttcttgcggttcttctcggggcggacatggtgg113866 accctcgggagttatggggcatggcgaaaggaggaggttgtctctatctgtttctggaac113926 cgctggaggtaatgaatctggtaagccctggaggccacatgtttttttagtcgcgttgcc113986 ttctgggatcgggtccgcgtgatcttcagatgactttcttttcagacctttacgggtctc114046 aaagtcatcatctggagggcggtcgggttcgggcccgtacggtgacacagataatggctc114106 ctgttcatcgcacggtggagctctgggccaggggttggcgggagattcttgggcagccga114166 aggctctgctccgttgccgccgccaggactcccgtagagtaggaggtgggccgcgcgatc114226 gggagtgccaggaggtaggtcgtaccggcaagtgctccgccggccgcctcgtcttttgcg114286 cctgtcatggtggtgggtgtcatcatctgcgggacaatcgtccgtgacgtgctcgctgcc114346 gggcgcggaatcatctcctagcatggtagcgatcatcctccaaccagaggccgcgtaggc114406 aattgaaggccgcacgtcaccctcgtcggagcagccaagcacgcccacggcagcttccat114466 ggcttctacaagaagagtgacatcatcggtagatggcagcggcagggaccctatgacgag114526 gcgactccatagcgaagccgcgcagtagcgcatggcgcgctcccacgtaaagactgtttt114586 gggcgccctcgagagtgcttgatacagatccgggcgacgcttggcggggtttattgtaac114646 tggtgggcagtctatagcagtaagcgccgccatgagatctgcggcagcaacaatgcaagt114706 tctagtatggcgcaatagcgccgaagaggaaagtttttccggggttgccgcaggtggctc114766 tttcgctgcggcttccagctccctcgtggcacgcgctattcgcctggcgccaacgagtac114826 agggtggtccccagaagcagacgccgccgtaggatccacggccgctcctggaaatacaaa114886 cgggacaaacgctctcctaagagccgccaacaggtaagttttctgcggatggtcatagcg114946 gcggcacacgcgtacgagctcggtaaggtgcggcagagctaatgacacacggccatcacg115006 catggcgtgcgctacgtgcgggaggcacgtcggcaccgcagaacgagacaatcctccctc115066 ggaagaacccggaccgcggagagcgcacagttcgcagagccgtttgtcacgtgggctcag115126 cttggggccgccatacccatacgaaacgcgcgacaggggctggaccatgaactcctccac115186 aaggcgctctaactgttccactggcatcccgtactcttcgagatacacggaagctgattt115246 cggattggcatggaattcggccgcggcctcccgaacctgcgggtcatcgaccaaagactg115306 tctatagccacttccatgatatacttgtcctctactgggtggggacgggataatagcttc115366 tggaacaaaaacgcgagcctcggaactatggaggtcgacggccaacgctcgtgagagtac115426 attcagggtaatgccgcggcctaggtctgggagctccgtaggcgcggttactgactgaac115486 cgacccgtctgtaccgtccgtttcgacccactccctcaaaactcgccagagtggctctag115546 cgcgacatcgggacattctccaggtagcactaattgggcagagtcccggtcggggctttc115606 ggcggatttttcacttcccgcgctttccagccttcgggcgagacgtcccctcctccctga115666 cagcgagaatgaggaagaggaggaagaggaggaagaggtaaggtggctcgggcccatctt115726 cttcgaaaattccctcttccctcgcttggggagacggtctttgctggtcctctgcggcga115786 agggacggggcgccggttgctcaaagatcgcgccacggcgcgtcgcgaacgagatctggc115846 cactctctctgacttcctcaccacttcttgacgcctcacagcggttgttttctctactgc115906 aggtaatggacacgggcattcaacgtgctgctgctccatgggagtttcgcagggatgtgc115966 gagcgagtcgatgaccgtataaactccgggctgatcggtatccacgttaatatctagtgc116026 cacgacatcactggtagcgttcggacacggttctatagagtttatgttttcgggatccat116086 gtcgtttaacatcgctataaggtcgcggagagacatttctcgcccgtccacgtcttgggc116146 cgcgtcttgggccgcattctcagcgatgacagagtgaaagagctcgtcctcgctggaaaa116206 aagaggtggcgtgctgtacgaaaagctatcagtagtggtctcacaggtaggtgcgtttgg116266 agggttcgggatgggagaacccaaagaatcgtagcgcccactcttatcggcgcgcaaaaa116326 ggtaaatagatctgagggcgggccagttgagaatcccgactcatcaacaattggagcggc116386 caaattactcggcgtcgaggaatcagaggacatgatagaatgctagtggaaggactagcg116446 atttccagaatcctgcagaacaagacccgagtgacaaggttacgtaagttttgtgcagaa116506 gttggaagaaacgtgaagctttctggtggggagtagtaacagaaaaaataaagatgcgcg116566 actctcgaaacctcccgtttctcgcgttggcctgtttatttccgtccccgcaatgcagag116626 cacaataaagctccgcaaccataggcacaattttggaacagcaatacatgctaaagaagt116686 ggattatcgttttgtgcgcttcatgttcatccataacagcagcccatactcttgactgta116746 tgggggaattattcgaagcccacagtcatatttttgcacgataccccatgcaaaaggata116806 tttcgtggtcccctcaaataatgacagcccacctaatcccaccccaaaatttataacaga116866 atattggtttcatgacttacgttttgcgaagaggtcctttccacgctgggtaggtttcag116926 caaaggtgttgtgaagaaagaactttggagagtcaacccctcggtcttgtgcagttggtt116986 tgggtatggcatttgtattgaggcatgatataattcagaaccaatggcgcccatgcggcc117046 tgcatatcgttagcgagcgtatttccagttccggtgtgccatagccaatgcatgccatgc117106 gcccagcataccattaccgtaccaggaacttccggcattttttatgagccaacataataa117166 acaaacctgagcctactgtagaacagatgacgaagataacaaaacaatacattgcttgtg117226 tccacaggtgcgtgcaattcggtgccggggtgtgtgcctactctagaaaggtcacgcgtg117286 ttttgttggcattgatattacccgagaaacacgctcgcttgcacgttattggccacaccg117346 ggaagcagtgaagtttattttgaatgccaaggaaagcacatgggtcacgcttcctgggag117406 tgccaaggaagttgtgacagaaaaaagatccccatatgggagagttgacatgtgtaaata117466 tcaccgtgagcacttgtgttacttgtgtgttctaatctctagcaattttccacgaaagat117526 tattatcttctagccacccctctaacccagcctaaataaaaaattcagacaacgcaaaag117586 cttggttccatgttccacgcgagtagttcgcgggaacacataattactttattgagacat117646 ttgccgctcgggatgcacgaatcgcaaattttgaatctcgggatgcgttctgtatttgca117706 gggcacttttcttcttttgagagatatggcgagaaggtccatgctcgggaatatagttcg117766 caatctggtttgcgatttacaaacggtgaagaaagaactttggagagtcaacccctcggt117826 cttgtgcagttggtttgggtatggcatttgtattgaggcatgatataattcagatccaat117886 ggcgcccatgcggcctgcatatcgttagcgagcgtatttccagttccggtgtgccatagc117946 caatgcatgccatgcgcccagcataccattaccgtaccaggaacttccggcattttttat118006 gagccaacataataaacaaacctgagcctactgtagaacagatgacgaagataacaaaac118066 aatacattgcttgtgtccacaggtgcgtgcaattcggtgccggggtgtgtgcctactcta118126 gaaaggtcacgcgtgttttgttggcattgatattacccgagaaacacgctcgcttgcacg118186 ttattggccacaccgggaagcagtgaagtttattttgaatgccaaggaaagcacatgggt118246 cacgcttcctgggagtgccaaggaagttgtgacagaaaaaagatccccatatgggagagt118306 tgacatgtgtaaatatcaccgtgagcacttgtgttacttgtgtgttctaatctctagcaa118366 ttttccacgaaagattattatcttctagccacccctctaacccagcctaaataaaaaatt118426 cagacaacgcaaaagcttggttccatgttccacgcgagtagttcgcgggaacacataatt118486 actttattgagacatttgccgctcgggatgcacgaatcgcaaattttgaatctcgggatg118546 cgttctgtatttgcagggcacttttcttcttttgagagatatggcgagaaggtccatgct118606 cgggaatatagttcgcaatctggtttgcgatttacaaacggtgaagaaagaactttggag118666 agtcaacccctcggtcttgtgcagttggtttgggtatggcatttgtattgaggcatgata118726 taattcagaaccaatggcgcccatgcggcctgcatatcgttagcgagcgtatttccagtt118786 ccggtgtgccatagccaatgcatgccatgcgcccagcataccattaccgtaccaggaact118846 tccggcattttttatgagccaacataataaacaaacctgagcctactgtagaacagatga118906 cgaagataacaaaacaatacattgcttgtgtccacaggtgcgtgcaattcggtgccgggg118966 tgtgtgcctactctagaaaggtcacgcgtgttttgttggcattgatattacccgagaaac119026 acgctcgcttgcacgttattggccacaccgggaagcagtgaagtttattttgaatgccaa119086 ggaaagcacatgggtcacgcttcctgggagtgccaaggaagttgtgacagaaaaaagatc119146 cccatatgggagagttgacatgtgtaaatatcaccgtgagcacttgtgttacttgtgtgt119206 tctaatctctagcaattttccacgaaagattattatcttctagccacccctctaacccag119266 cctaaataaaaaattcagacaacgcaaaagcttggttccatgttccacgcgagtagttcg119326 cgggaacacataattactttattgagacatttgccgctcgggatgcacgaatcgcaaatt119386 ttgaatctcgggatgcgttctgtatttgcagggcacttttcttcttttgagagatatggc119446 gagaaggtccatgctcgggaatatagttcgcaatctggtttgcgatttacaaacggtgaa119506 gaaagaactttggagagtcaacccctcggtcttgtgcagttggtttgggtatggcatttg119566 tattgaggcatgatataattcagatccaatggcgcccatgcggcctgcatatcgttagcg119626 agcgtatttccagttccggtgtgccatagccaatgcatgccatgcgcccagcataccatt119686 accgtaccaggaacttccggcattttttatgagccaacataataaacaaacctgagccta119746 ctgtagaacagatgacgaagataacaaaacaatacattgcttgtgtccacaggtgcgtgc119806 aattcggtgccggggtgtgtgcctactctagaaaggtcacgcgtgttttgttggcattga119866 tattacccgagaaacacgctcgcttgcacgttattggccacaccgggaagcagtgaagtt119926 tattttgaatgccaaggaaagcacatgggtcacgcttcctgggagtgccaaggaagttgt119986 gacagaaaaaagatccccatatgggagagttgacatgtgtaaatatcaccgtgagcactt120046 gtgttacttgtgtgttctaatctctagcaattttccacgaaagattattatcttctagcc120106 acccctctaacccagcctaaataaaaaattcagacaacgcaaaagcttggttccatgttc120166 cacgcgagtagttcgcgggaacacataattactttattgagacatttgccgctcgggatg120226 cacgaatcgcaaattttgaatctcgggatgcgttctgtatttgcagggcacttttcttct120286 tttgagagatatggcgagaaggtccatgctcgggaatatagttcgcaatctggtttgcga120346 tttacaaacgttcctgtaattttcttacgcggatctggaagtaatcgcaggagcctctcc120406 gcaggagacttgccgattcgccggtgaatcgcaaatacacttccagatatatatgtcggg120466 gggtcaaggcactgtctctacaggtttcttttaggaaacgcacctatgtcggattgcccg120526 tgggactaaaaccagttatctgcgcgtggaagcagccgcaggcttagcagatgcgctcga120586 aacaaagcacgagttgcaatagccggtataatatcaaggtacgggctatatacatgcgcg120646 taatacatccatactggatctacccagtaatcgtgttaactgacggtgttacaacgcagt120706 cgtagcagtaatatgaaagtatgcaatatgtatgcaataagcaagggcaacgaagccgat120766 aacctgcacgtcggtgggcccaaacaactcagcggccctattaaagagcaaataaagtag120826 tgagcccggcacatgccgaacggctcaagtaaaaacaaaaattcataaagtgcaaacccg120886 cctatggcggttcagtgttaactagctcttcacgacaatcgactttgttgggtccttatt120946 ttctgggtcaggtaaactcgaacatgagctttcgtagagtatttttaacccgcgatgtct121006 tggagagtatcggtcacgcagcctccggatgagttcatcccgccgaatatcacttcccga121066 tcacattcagggtcgggggtcgaggggggtgctcgacccgggtcgtgtgtatcgtgagga121126 caagcctctccgatcggcgacccatccccatctgggacagtgcatggctttaaacggagc121186 ctgcgtcggcgtggtctggaggcatcggcggggggattttcgggttgctcatgtgagaag121246 acaatgacccatcccattgtgcccccagtatgaaatcttctcccctcttcctggggtaat121306 ccgagcaggacccgatggtcccgctatatgcggggacagcgacctggatcgttcttttat121366 gcagtgcccgaagatgcaagtcacagctcattggctggaagggggatgcaggaccctcgg121426 tgcgaacgtgacgtaggtgggtgccacccacatcatgtaaattaggtcacggggtaggat121486 tccggctccgcgattggttatgaggcccctaaagcaaacattcgcactccagtatttaat121546 atattaggttttccctaatatattaaatactggagtgcgaatgtttgctttaggggcctc121606 ataaccaatcgcggagccggaatcctaccccgtgacctaatttacatgatgtgggtggca121666 cccacctacgtcacgttcgcaccgagggtccaacattttcctaaaatggcaaagcgggac121726 tggggtccgtgggtaaattttctaattttttcccacggtctgtcgcaagagcgtattctc121786 caagatagaatgctgttagattttcccgaattttgtcgaggtcacgcgttttgtaatgga121846 atatggcgcgagaatattgagtttaaattttgtccgcgcgccaaacttgaagtgatatta121906 ggacatagtcaaccaaccgacatacgttgaaccatttgcgggcagcgctgagggaagacg121966 agatgtatggacaacacaacgaccggagaagagggcgtaaagaacatcacggtcttgctc122026 tacggtggggggtaacaacaatttaataaataaaaagtttctttaatataagagcggtat122086 agcagatttaataaaacaccttttttgaaaaaatattgacctgtctcgttgtagattctt122146 cgcatccgcgttccgtcattattccaagattttgcgtttcattccaattcaatcaatcct122206 agaaggcaaaagaaaacataacacgcaaatataaggatcggtattttgacattttaaatg122266 tgtttttaaggaaaagggtagaactttggggaggagttggtacgtggtagtcacaatttg122326 acagacaggtagacagacaacgaattacaagcggcctagggtaatagcgctgagcccatg122386 atgtgtccgtgcatatgagacgactaataaggtagtcacgtaaacccccgtcaatcacac122446 gcgaaagaaagaaagaaaggaaaaggcctcaaagcaaattttgtagcttaaaaaagaggg122506 ggccctaaagaagaagcaacatcgtctcgggctgtgtttccgacgttggggtgcattatg122566 cgattttactaccagtgtttggtgtggtgtggtaaggggaaatgagacgagaatttttcg122626 cgtgcgctcgaggacagagctacgcccaaccgtgagcaaattgcgcggcgcttccttgtt122686 agcgtggcgtcacgtataaatgcacagaagcttcgtcagtaacgaagcgcctctgccaga122746 gttattaacattaggactcgagagagtctcgagaagagacttctcaaagagagtgccgct122806 ttgatctccagatcacttcacagcccattaagacttttcctttttgacacacgagtaggg122866 cgatattttgtgcttatccgagaacggccgcaaaccacggcctactcgaaccgcgcattc122926 cctgcggaaagacaacacgagtaaataagacccagtgcgcaagatatgagccacagtcct122986 ttgtcgagtgatccctctcccttgccagaagagacctatccgtcgccccgcggaaagtca123046 ccagagcagcttccctgggatcccgaagagctctcccagaagtttttcttttcggacgta123106 tcggaggacgaagaaccggcacgcgggaggagctggagcgacccggagtcggaggaagag123166 cagcctgggtgccggggagtggacttgggcgaggaggacacgggacacagctccaccgag123226 tcagagcccacgcaatctgacttagactttattgacgacagctctccggcgccgccgcca123286 tttgctatcccccgcgtccgtgcgttattgcggtgcgcggcaccccgcaaagacccacgg123346 aaggcttcggccgccagggcgggtaggcgcactcttaaaagacggaggttgtcattttct123406 tcttcctctgacgaggaatccgaggagagaagtaaaaaagaagaagcggcctcgacccct123466 gcacggcgacgcaaggccgaggcctcgacgagcagatagaggagacgcggggcagaacct123526 ccccctccctcccacccccctactctggacatttattgcccgctcgatccattctcatcc123586 agaacttctttcccgctcagccttcacgcagaagcggacgcgcgcccctttgcgaccgcc123646 ggacatcccgccgcccccccccccttcacgcccggcgcaatccgtagccgtccaactcgg123706 cccagcacaaccgcagtagaccgcccggaccgctctcctctagacacatccctaaatgga123766 aaacatgctcgacgggtgctacccgctggcgctgatggacagcgatcacattactgcgca123826 cgcggtacctcgtggcgagcgcaggcggcaaggtgccgctgtcgcctcgtcggagtcggc123886 cgactcggtagacccgtgcattcggatcgcctcgcggctctggcgcgagttagtcgagat123946 atcgtccgaactcaaggacggttacggagagttcacgtcagcgagagaccgccgcaacgc124006 gctgattgctgccaacgaacggctacgttcggcttttctgggggccagccgggcgacgcg124066 cggcctaggtttgaggccgcggtgggcgtcgacggagagcgtcgccaactcccccactga124126 cccgaataacggcaacgggttgggagaattagaggaggcaatggaagggatcgagggcga124186 tttctggctcgactctctggacggtgaccgcttcgaggacgagagccgtaccatgcagag124246 cgagaatatgcgtttcgtgatcgagaaagaactgttatcctggctgtcccgacacctgcc124306 ggccgacctcgcgtccgccgagcgagagacctcccggtctctcctggcggccgggcactg124366 gtgctgcttgtggcaccctcggccgtgccgcgaagcgtgtttgtacgactcgatttacgt124426 gcagagtcttttctgcgtcgggacggggagagtcccgcaatcggagatgcgccgtcgcga124486 atacctggccgccttgcgcgccggcgcggctgccgccaactctcccgaagtgagcgcctc124546 gatctttgcgagggacgctggaatcgcgctggcgctggcgcggcgccgttgacgggagaa124606 tgacgccctctagcggcttccttacctccgcgtccctgacaacctcgcgggtttttacac124666 tgtcctccgtccactctcccccctcacccactccgcggcagcgaaacacaaccccccccc124726 tccccagaaacgagcgacacgcgagcgctgcgaaataaataaagtaatattattgtgtgt124786 ttttcacgttgttgcaatcgagaggccgtttgtctgtctgtgtctgtgcggagctaggct124846 ttcccgggcggccccgttccaccgttcggttaggccggtggcgacgggacatagagaaag124906 atagagcgcgcgccctggcggcgagagggtgttgcgggggtaaatgggaccctgagctca124966 ccattttggcgggggattgcacgggtaacaaaaagctctctcgcacataatgatttccct125026 taaacagtggctgtaaaagctttcttcgactgggacgcgcacgtccggagacatgatctt125086 atcggtagctacacagttcatgaggtgggccacgaacgcgcggatcgagttttgggaacc125146 ttcggggaggtcttccgggagggtgaagtttgacagaggcagcgctatcaccaggaggct125206 ccgcaccatctccatgcctatccttatcgccgcgagtccggcggccggcgcgctgctctg125266 gttattccagtgcgcggaccgcgagtgcgcccctccccgggctctgatatagagcaccgg125326 cagctcgacggcggcggagaaaaaagaaagaatgtccggcccaatgactggaactttggg125386 cacgtctcttatttcccacgcggcggcccggggaatctgcttgccccagaccttgctttc125446 caactccccgttcggccccccaactaactccgacagcgcggtccacagtcctaccgccgc125506 tgcgacggcgcgcttagccgcgggcgctattcgcgggtcgtgcgccgtgatatcttcggc125566 gacctgcagactgcccagcctttccttcccttcaaaatacgcgcgggcggcctgtacgat125626 caccgcggccagatcgggccaaaagaaaatatcgcaactctgcgacgcccgccagaatct125686 ccctccgggcaggtccgtgcccctaaaggccgccgagaaagctaagtccaaatgtgacgt125746 cggaggtctcgacatggtcgccaaccctccaaatgctacccgccggcccacgcaacgcgg125806 gcttttataaagatggcgcgcgagacaataacacttactcatccgcgtacgcgtttatta125866 ttgtcaatatttgtgtggttattattactgctaccgcccttgtttctgcaaggccctcgc125926 cgcggcccaggccactattccggcagcggccgccgacgcggcgagcgtcgccgctaacgt125986 cggcgccgcggggagcggggtttcttcgacttaaatagactcccgagaaaaaattttggc126046 tgccgttcgccatcatccgagtcggaaacacagtatgcggccgagttaggttttactttt126106 aaaaactttaccgtgctgtacggccagggcgttctcaggctcgaaggggcaagagttgtc126166 cagactgatgggtgactcagagacagcgttgtcttgtctccgtttaccaaaaatatttcc126226 actcctctctcaaaatttttacctccggtttcggtaattaggaaagtttttggcgcaggg126286 aggtttaaagctgccatgcatatgtcagcggtacccagcacccacaaatggaactctttt126346 gcggcatacgcgccagatgacaaatggtaaaaccctgcgtccaagccgctccactcggga126406 cttactccaggcgggtcgcccccctcaccgaaccgaatcacgggtctgcacatcctggga126466 agggaaaacagctccccggaaacttcgtacagagatgccgggcgcacgattaccgataat126526 gtactcggacgatcgtaactcgccatagttttcactgcgtgaaccaattctttccatcca126586 gaatccgagagctcaaatctagaattaggtagtttgtagtgcgaatcgaccgcagaaact126646 atagtcacttttacaggcgccatcgccgctcagactccaccccgctatgatgtcagaaat126706 ataacgctcttattctagcagagtcaggccaatatatacagcttagagaagatgcggttt126766 cggcgcatctgttcacgctctagggcagaaaaacgaagaagaacaaccgagaatccgctt126826 acctcaaaacgcgtttgcgtattggatagtttctcacggacaatgtcattgcgcccctat126886 gcagaaattttgccgaccgcggaaggcgtcgagcgcctcgccgaacttgttagcgtgaca126946 atgacagaacgcgcggaacctgtgacagagaatacagctgtaaacagtatccccccggct127006 aacgagaacgggcagaacttcgcatatgcaggcgatgggccctcgactactgaaaaagtt127066 gacggctcgcatacagacttcgatgaagcatcgagcgactacgccggccctgtcccgctc127126 gcgcaaactagattgaagcattcggatgaatttcttcagcacttccgagttttagacgat127186 ttggtggagggggcttacgggtttatctgcgacgtccgtcgctacaccgaggaagagcaa127246 cgtcgaagaggggttaacagtactaaccaggggaaatcaaaatgtaagcgcctgatagct127306 aaatatgtgaaaaatggaacaagggcggcctctcagctggaaaatgaaattttggttctc127366 gggcgcctaaatcacgagaatgttctcaagatccaggaaatccttcggtacccggataat127426 acgtacatgttaacgcagaggtatcagttcgacttgtacagctacatgtacgatgaagcg127486 ttcgactggaaagacagtccaatgcttaaacagactagacgcatcatgaagcagctcatg127546 tcagcggtctcgtatatccattcaaagaaactgattcacagggacatcaaactcgaaaat127606 attttcttaaactgcgacggcaagacagtgctgggcgactttggaactgtcacgcctttt127666 gaaaatgagcgggagcccttcgaatatggatgggtggggaccgtggctactaactctccc127726 gagatactcgccagggattcgtactgtgaaattacagacatttggagctgcggagtagta127786 ttgctggaaatggtaagccatgaattttgcccgatcggcgatggcgggggaaatccgcac127846 cagcaattgctgaaagttatcgactctctctcagtttgtgatgaagagttcccagacccc127906 ccgtgtaatctgtacaattatttgcattatgcgagcatcgatcgcgccggacatacggtc127966 ccgtcgctcatacggaacctccaccttccggcggatgtggaataccctctagttaaaatg128026 cttacttttgactggcgtttgagacccagcgcggccgaagtattggcaatgccactgttt128086 tcggctgaagaggaacggaccataacaattattcatggaaaacataaacccatccgaccc128146 gaaatccgtgcgcgggtgccacggtccatgagtgaaggttaataataaaggacggagata128206 gagaactgaagcgtcagatttttttaaaaaaataaatgatcgagaacttatgatttgtct128266 ttcttgaatgaccttgccccatcgattaacgaaaagacctttcgcgcgtcgattctgctc128326 ggtctttgtgatacattatagtgagactaaactcgaccgatataacaagacaatgttact128386 ctatagaccggactcaaccatgcggcatagcggaggcgacgcaaatcacagagggataag128446 gccgaggcggaaatctattggagcgtttagcgcgcgcgaaaagactggaaaacgaaatgc128506 gctgacggaaagcagctcctcctccgacatgctagatccgttttccacggataaggaatt128566 tggcggtaagtggacggtagacggacctgccgacattactgccgaggtcctttctcaggc128626 atgggacgttctccaattagtgaagcatgaagatgcggaggaggagagagtgacttatga128686 gtccaaaccgaccccgatacagccgttcaatgcctggccggacgggccgagttggaacgc128746 gcaggattttactcgagcgccaatagtttatccctctgcggaggtattggacgcagaggc128806 gttgaaagtaggggcattcgttagccgagttttacaatgtgtaccgttcacgcgatcaaa128866 gaaaagcgttacggtgcgggatgcgcagtcgtttttgggggactcgttctggagaataat128926 gcagaacgtttacacggttgtcttacgacagcacataactcgactcaggcacccttccag128986 caaaagcattgttaactgcaacgaccctctatggtacgcctacgcgaatcaatttcactg129046 gagaggaatgcgcgtgccgtcgcttaaattagcctctcccccggaggagaatattcaaca129106 cgacccaatggccgccgtttttagaaacgcgggggctggtctgttcctgtggcctgccat129166 gcgcgcagcctttgaagagcgcgacaagcgactgttaagagcatgcctgtcttcactcga129226 tatcatggacgcagccgtcctcgcgtcgtttccattttactggcgcggcgtccaagacac129286 ctcgcgcttcgagcctgcgctgggctgtttgtcagagtactttgcactagtggtgttact129346 ggccgagacggtcttagcgaccatgttcgaccacgcactggtattcatgagggcgctggc129406 agacggcaatttcgatgactatgacgaaactagatatatagaccccgttaaaaacgagta129466 cctgaacggagccgagggtactctgttacggggcatagtggcctccaacaccgctctggc129526 ggtggtttgcgcaaacacctattcgacgataagaaaactcccgtccgtggcaactagcgc129586 gtgcaatgttgcctacaggaccgaaacgctgaaagcgaggcgccctggcatgagcgacat129646 ataccggatattacaaaaagagtttttcttttacattgcgtggctccagagggttgcaac129706 acacgcaaatttctgtttaaacattctgaagagaagcgtggatacgggggccccgccatt129766 tttgttcagggccagctcggagaagcggctgcagcagttaaataaaatgctctgccccct129826 tctcgtgccgattcaatatgaagacttttcgaaggccatggggtctgagctcaagaggga129886 aaagttagagacattcgttaaagctatttccagcgacagggacccgagggggtccttaag129946 atttctcatttcggaccatgcaagggaaattattgcagacggagtacggtttaagccggt130006 gatagacgagccggttcgggcttcagttgcgctgagtaccgctgccgctgggaaagtgaa130066 agcgcgacgcttaacctcagttcgcgcgcccgtaccgggcgcaggcgccgtttccgcgcg130126 ccggaaatcggaaatatgataaaaatgcttggcatttgcgggcgaagaggcgtgatctga130186 agggctccacaatgacgtaactgagctacgcatccctataaagtgtacccgctgaccgct130246 agcccatacagtgttacaggaggggagagagacaacttcagctcgaagtctgaagagaca130306 tcatgagcggcttcagtaacataggatcgattgccaccgtttccctagtatgctcgcttt130366 tgtgcgcatctgtattaggggcgccggtactggacgggctcgagtcgagccctttcccgt130426 tcgggggcaaaattatagcccaggcgtgcaaccgcaccacgattgaggtgacggtcccgt130486 ggagcgactactctggtcgcaccgaaggagtgtcagtcgaggtgaaatggttctacggga130546 atagtaatcccgaaagcttcgtgttcggggtggatagcgaaacgggcagtggacacgagg130606 acctgtctacgtgctgggctctaatccataatctgaacgcgtctgtgtgcagggcgtctg130666 acgccgggatacctgatttcgacaagcagtgcgaaaaagtgcagagaagactgcgctccg130726 gggtggaacttggtagttacgtgtctggcaatggatccctggtgctgtacccagggatgt130786 acgatgccggcatctacgcctaccagctctcagtgggtgggaagggatataccgggtctg130846 tttatctagacgtcggaccaaaccccggatgccacgaccagtatgggtacacctattaca130906 gcctggccgacgaggcgtcagacttatcatcttatgacgtagcctcgcccgaactcgacg130966 gtcctatggaggaagattattccaattgtctagacatgcccccgctacgcccatggacaa131026 ccgtttgttcgcatgacgtcgaggagcaggaaaacgccacggacgagctttacctatggg131086 acgaggaatgcgccggtccgctggacgagtacgtcgacgaaaggtcagagacgatgccca131146 ggatggttgtcttttcaccgccctctacgctccagcagtagccacccgagagtgtttttt131206 gtgagcgcccacgcaacatacctaactgcttcatttctgatcaattattgcgtattgaat131266 aaataaacagtacaaaagcatcaggtgtggtttgcgtgtctgtgctaaaccatggcgtgt131326 gcgggtgaaaccgtaaattacgtgataataaatagcataggagttggcgtgcagcgtatt131386 tcgccgagagatggggacaatgttagtgttgcgccttttcctacttgcagtagcggacgc131446 ggcgttgccgaccggcagattctgccgagtttggaaggtgcctccgggaggaaccatcca131506 agagaacctggcggtgctcgcggaatcgccggtcacgggacacgcgacatatccgccgcc131566 tgaaggcgccgtcagctttcagatttttgcggacacccctactttgcgcattcgctacgg131626 cgctacggaggacgaacttgcactggagcgcgggacgtccgcctcagacgcggacaacgt131686 gacattttcgctgtcatatcgcccgcgcccagaaattcacggagcatacttcaccatagg131746 ggtattcgctactggccagagcacggaaagcagctattcggtcatcagtcgggtcttagt131806 taacgcctctctggaacggtccgtgcgcctggaaacgccgtgcgatgaaaattttttgca131866 gaacgagcctacatggggctcgaagcgttggttaggccccccgtcgccttatgtgcgaga131926 taacgatgtcgccgtgttgacaaaagcgcagtacattggggagtgctactccaactcggc131986 ggcccagacggggctcacgtctctcaacatgacctttttctattcgcctaaaagaatagt132046 aaacgtcacgtggacaaccggcggcccctccccctcgcgcataacggtatactcgtcgcg132106 ggagaacgggcagcccgtgttgaggaacgtttctgacgggttcttggttaagtacactcc132166 cgacattgacggccgggccatgataaacgttattgccaattattcgccggcggactccgg132226 cagcgtcctcgcgtttacggcctttagggaaggaaaactcccatccgcgattcaactgca132286 ccggatagatatgtccgggactgagccgccggggactgaaacgaccttcgactgtcaaaa132346 aatgatagaaaccccgtaccgagcgctcgggagcaatgttcccagggacgactctatccg132406 tccgggggccactctgcctccgttcgataccgcagcacctgatttcgatacaggtacttc132466 cccgacccccactaccgtgccagagccagccattactacactcataccgcgcagcactag132526 cgatatgggattcttctccacggcacgtgctaccggatcagaaactctttcggtacccgt132586 ccaggaaacggatagaactctttcgacaactcctcttacccttccactgactcccggtga132646 gtcagaaaatacactgtttcctacgaccgcgccggggatttctaccgagaccccgagcgc132706 ggcacatgaaactacacagacccagagtgcagaaacggtggtctttactcagagtccgag132766 taccgagtcggaaaccgcgcggtcccagagtcaggaaccgtggtattttactcagactcc132826 gagtactgaacaggcggctcttactcagacgcagatcgcagaaacggaggcgttgtttac132886 tcagactccgagtgctgaacagatgacttttactcagactccgggtgcagaaaccgaggc132946 acctgcccagaccccgagcacgatacccgagatatttactcagtctcgtagcacgccccc133006 cgaaaccgctcgcgctccgagcgcggcgccggaggtttttacacagagttcgagtacggt133066 aacggaggtgtttactcagaccccgagcacggtaccgaaaactactctgagttcgagtac133126 tgaaccggcgatttttactcggactcagagcgcgggaactgaggcctttactcagacttc133186 gagtgccgagccggacactatgcgaactcagagtactgaaacacactttttcactcaggc133246 cccgagtacggtaccgaaagctactcagactccgagtacagagccggaggtgttgactca133306 gagtccgagtaccgaacctgtgcctttcacccggactctgggcgcagagccggaaattac133366 tcagaccccgagcgcggcaccggaggtttatactcggagttcgagtacgatgccagaaac133426 tgcacagagcacacccctggcctcgcaaaaccctaccagttcgggaaccgggacgcataa133486 tactgaaccgaggacttatccagtgcaaacgacaccacatacccagaaactctacacaga133546 aaataagactttatcgtttcctactgttgtttcagaattccatgagatgtcgacggcaga133606 gtcgcagacgcccctattggacgtcaaaattgtagaggtgaagttttcaaacgatggcga133666 agtaacggcgacttgcgtttccaccgtcaaatctccctatagggtagaaactaattggaa133726 agtagacctcgtagatgtaatggatgaaatttctgggaacagtcccgccggggtttttaa133786 cagtaatgagaaatggcagaaacagctgtactacagagtaaccgatggaagaacatcggt133846 ccagctaatgtgcctgtcgtgcacgagccattctccggaaccttactgtcttttcgacac133906 gtctcttatagcgagggaaaaagatatcgcgccagagttatactttacctctgatccgca133966 aacggcatactgcacaataactctgccgtccggcgttgttccgagattcgaatggagcct134026 taataatgtttcactgccggaatatttgacggccacgaccgttgtttcgcataccgctgg134086 ccaaagtacagtgtggaagagcagcgcgagagcaggcgaggcgtggatttctggccgggg134146 aggcaatatatacgaatgcaccgtcctcatctcagacggcactcgcgttactacgcgaaa134206 ggagaggtgcttaacaaacacatggattgcggtggaaaacggtgctgctcaggcgcagct134266 gtattcactcttttctggacttgtgtcaggattatgcgggagcatatctgctttgtacgc134326 aacgctatggaccgccatttatttttgaggaatgctttttggactatcgtactgctttct134386 tccttcgctagccagagcaccgccgccgtcacgtacgactacattttaggccgtcgcgcg134446 ctcgacgcgctaaccataccggcggttggcccgtataacagatacctcactagggtatca134506 agaggctgcgacgttgtcgagctcaacccgatttctaacgtggacgacatgatatcggcg134566 gccaaagaaaaagagaaggggggccctttcgaggcctccgtcgtctggttctacgtgatt134626 aagggcgacgacggcgaggacaagtactgtccaatctatagaaaagagtacagggaatgt134686 ggcgacgtacaactgctatctgaatgcgccgttcaatctgcacagatgtgggcagtggac134746 tatgttcctagcacccttgtatcgcgaaatggcgcgggactgactatattctcccccact134806 gctgcgctctctggccaatacttgctgaccctgaaaatcgggagatttgcgcaaacagct134866 ctcgtaactctagaagttaacgatcgctgtttaaagatcgggtcgcagcttaacttttta134926 ccgtcgaaatgctggacaacagaacagtatcagactggatttcaaggcgaacacctttat134986 ccgatcgcagacaccaatacacgacacgcggacgacgtatatcggggatacgaagatatt135046 ctgcagcgctggaataatttgctgaggaaaaagaatcctagcgcgccagaccctcgtcca135106 gatagcgtcccgcaagaaattcccgctgtaaccaagaaagcggaagggcgcaccccggac135166 gcagaaagcagcgaaaagaaggcccctccagaagactcggaggacgacatgcaggcagag135226 gcttctggagaaaatcctgccgccctccccgaagacgacgaagtccccgaggacaccgag135286 cacgatgatccaaactcggatcctgactattacaatgacatgcccgccgtgatcccggtg135346 gaggagactactaaaagttctaatgccgtctccatgcccatattcgcggcgttcgtagcc135406 tgcgcggtcgcgctcgtggggctactggtttggagcatcgtaaaatgcgcgcgtagctaa135466 tcgagcctagaataggtggtttcttcctacatgccacgcctcacgctcataatataaatc135526 acatggaatagcataccaatgcctattcattgggacgttcgaaaagcatggcatcgctac135586 ttggaactctggctctccttgccgcgacgctcgcacccttcggcgcgatgggaatcgtga135646 tcactggaaatcacgtctccgccaggattgacgacgatcacatcgtgatcgtcgcgcctc135706 gccccgaagctacaattcaactgcagctatttttcatgcctggccagagaccccacaaac135766 cctactcaggaaccgtccgcgtcgcgtttcggtctgatataacaaaccagtgctaccagg135826 aacttagcgaggagcgctttgaaaattgcactcatcgatcgtcttctgtttttgtcggct135886 gtaaagtgaccgagtacacgttctccgcctcgaacagactaaccggacctccacacccgt135946 ttaagctcactatacgaaatcctcgtccgaacgacagcgggatgttctacgtaattgttc136006 ggctagacgacaccaaagaacccattgacgtcttcgcgatccaactatcggtgtatcaat136066 tcgcgaacaccgccgcgactcgcggactctattccaaggcttcgtgtcgcaccttcggat136126 tacctaccgtccaacttgaggcctatctcaggaccgaggaaagttggcgcaactggcaag136186 cgtacgttgccacggaggccacgacgaccagcgccgaggcgacaaccccgacgcccgtca136246 ctgcaaccagcgcctccgaacttgaagcggaacactttacctttccctggctagaaaatg136306 gcgtggatcattacgaaccgacacccgcaaacgaaaattcaaacgttactgtccgtctcg136366 ggacaatgagccctacgctaattggggtaaccgtggctgccgtcgtgagcgcaacgatcg136426 gcctcgtcattgtaatttccatcgtcaccagaaacatgtgcaccccgcaccgaaaattag136486 acacggtctcgcaagacgacgaagaacgttcccaaactagaagggaatcgcgaaaatttg136546 gacccatggttgcgtgcgaaataaacaagggggctgaccaggatagtgaacttgtggaac136606 tggttgcgattgttaacccgtctgcgctaagctcgcccgactcaataaaaatgtgattaa136666 gtctgaatgtggctctccaatcatttcgattctctaatctcccaatcctctcaaaagggg136726 cagtatcggacacggactgggaggggcgtacacgatagttatatggtacagcagaggcct136786 ctgaacacttaggaggagaattcagccggggagagcccctgttgagtaggcttgggagca136846 tattgcaggatgaacatgttagtgatagttctcgcctcttgtcttgcgcgcctaactttt136906 gcgacgcgacacgtcctctttttggaaggcactcaggctgtcctcggggaagatgatccc136966 agaaacgttccggaagggactgtaatcaaatggacaaaagtcctgcggaacgcgtgcaag137026 atgaaggcggccgatgtctgctcttcgcctaactattgctttcatgatttaatttacgac137086 ggaggaaagaaagactgcccgcccgcgggacccctgtctgcaaacctggtaattttacta137146 aagcgcggcgaaagcttcgtcgtgctgggttctgggctacacaacagcaatataactaat137206 atcatgtggacagagtacggaggcctgctctttgatcctgtaactcgttcggacgaggga137266 atctattttcgacggatctctcagccagatctggccatggaaactacatcgtacaacgtc137326 agcgttctttcgcacgtagacgagaaggctccagcaccgcacgaggtggagatagacacc137386 atcaagccgtcagaggcccacgcgcacgtggaattacaaatgctgccgtttcatgaactc137446 aacgacaacagccccacctatgtgacccctgttcttagagtcttcccaccgaccgagcac137506 gtaaaatttaacgttacgtattcgtggtatgggtttgatgtcaaagaggagtgcgaagaa137566 gtgaaactgttcgagccgtgcgtataccatcctacagacggcaaatgtcagtttcccgca137626 accaaccagagatgcctcataggatctgtcttgatggcggaattcttgggcgcggcctct137686 ttgctggattgttcccgcgatactctagaagactgccacgaaaatcgcgtgccgaaccta137746 cggttcgattcgcgactctccgagtcacgcgcaggcctggtgatcagtcctcttatagcc137806 atccccaaagttttgattatagtcgtttccgacggagacattttgggatggagctacacg137866 gtgctcgggaaacgtaacagtccgcgcgtagtagtcgaaacgcacatgccctcgaaggtc137926 ccgatgaacaaagtagtaattggcagtcccggaccaatggacgaaacgggtaactataaa137986 atgtacttcgtcgtcgcgggggtggccgcgacgtgcgtaattcttacatgcgctctgctt138046 gtggggaaaaagaagtgccccgcgcaccaaatgggtactttttccaagaccgaaccattg138106 tacgcgccgctccccaaaaacgagtttgaggccggcgggcttacggacgatgaggaagtg138166 atttatgacgaagtatacgaacccctatttcgcggctactgtaagcaggaattccgcgaa138226 gatgtgaatacctttttcggtgcggtcgtggagggagaaagggccttaaactttaaatcc138286 gccatcgcatcaatggcagatcgcatcctggcaaataaaagcggcagaaggaatatggat138346 agctattagttggtcatgccttttaagaccagaggggccgaagacgcggccgcgggcaag138406 aacaggtttaagaaatcgagaaatcgggaaatcttaccgaccagactgcgtggcaccggt138466 aagaaaactgccggattgtccaattatacccagcctattccctggaaccctaaattctgc138526 agcgcgcgcggggaatctgacaaccacgcgtgtaaagacactttttatcgcaggacgtgc138586 tgcgcatcgcgctctaccgtttccagtcaacccgattccccccacacacccatgcctact138646 gagtatgggcgcgtgccctccgcaaagcgcaaaaaactatcatcttcagactgcgagggc138706 gcgcaccaacccctagtatcctgtaaacttccggattctcaagcagcaccggcgcgaacc138766 tatagttctgcgcaaagatatactgttgacgaggtttcgtcgccaactccgccaggcgtc138826 gacgctgttgcggacttagaaacgcgcgcggaacttcctggcgctacgacggaacaaacg138886 gaaagtaaaaataagctccccaaccaacaatcgcgcctgaagccgaaacccacaaacgag138946 cacgtcggaggggagcggtgcccctccgaaggcacggtcgaggcgccatcgctcggcatc139006 ctctcgcgcgtcggggcagcgatagcaaacgagctggctcgtatgcggagggcgtgtctt139066 ccgctcgccgcgtcggcggccgctgccggaatagtggcctgggccgcggcgagggccttg139126 cagaaacaagggcggtagcagtaataataaccacacaaatattgacaataataaacgcgt139186 acgcggatgagtaagtgttattgtctcgcgcgccatctttataaaagcccgcgttgcgtg139246 ggccggcgggtagcatttggagggttggcgaccatgtcgagacctccgacgtcacatttg139306 gacttagctttctcggcggcctttaggggcacggacctgcccggagggagattctggcgg139366 gcgtcgcagagttgcgatattttcttttggcccgatctggccgcggtgatcgtacaggcc139426 gcccgcgcgtattttgaagggaaggaaaggctgggcagtctgcaggtcgccgaagatatc139486 acggcgcacgacccgcgaatagcgcccgcggctaagcgcgccgtcgcagcggcggtagga139546 ctgtggaccgcgctgtcggagttagttggggggccgaacggggagttggaaagcaaggtc139606 tggggcaagcagattccccgggccgccgcgtgggaaataagagacgtgcccaaagttcca139666 gtcattgggccggacattctttcttttttctccgccgccgtcgagctgccggtgctctat139726 atcagagcccggggaggggcgcactcgcggtccgcgcactggaataaccagagcagcgcg139786 ccggccgccggactcgcggcgataaggataggcatggagatggtgcggagcctcctggtg139846 atagcgctgcctctgtcaaacttcaccctcccggaagacctccccgaaggttcccaaaac139906 tcgatccgcgcgttcgtggcccacctcatgaactgtgtagctaccgataagatcatgtct139966 ccggacgtgcgcgtcccagtcgaagaaagcttttacagccactgtttaagggaaatcatt140026 atgtgcgagagagctttttgttacccgtgcaatcccccgccaaaatggtgagctcagggt140086 cccatttacccccgcaacaccctctcgccgccagggcgcgcgctctatctttctctatgt140146 cccgtcgccaccggcctaaccgaacggtggaacggggccgcccgggaaagcctagctccg140206 cacagacacagacagacaaacggcctctcgattgcaacaacgtgaaaaacacacaataat140266 attactttatttatttcgcagcgctcgcgtgtcgctcgtttctggggagggggggggttg140326 tgtttcgctgccgcggagtgggtgaggggggagagtggacggaggacagtgtaaaaaccc140386 gcgaggttgtcagggacgcggaggtaaggaagccgctagagggcgtcattctcccgtcaa140446 cggcgccgcgccagcgccagcgcgattccagcgtccctcgcaaagatcgaggcgctcact140506 tcgggagagttggcggcagccgcgccggcgcgcaaggcggccaggtattcgcgacggcgc140566 atctccgattgcgggactctccccgtcccgacgcagaaaagactctgcacgtaaatcgag140626 tcgtacaaacacgcttcgcggcacggccgagggtgccacaagcagcaccagtgcccggcc140686 gccaggagagaccgggaggtctctcgctcggcggacgcgaggtcggccggcaggtgtcgg140746 gacagccaggataacagttctttctcgatcacgaaacgcatattctcgctctgcatggta140806 cggctctcgtcctcgaagcggtcaccgtccagagagtcgagccagaaatcgccctcgatc140866 ccttccattgcctcctctaattctcccaacccgttgccgttattcgggtcagtgggggag140926 ttggcgacgctctccgtcgacgcccaccgcggcctcaaacctaggccgcgcgtcgcccgg140986 ctggcccccagaaaagccgaacgtagccgttcgttggcagcaatcagcgcgttgcggcgg141046 tctctcgctgacgtgaactctccgtaaccgtccttgagttcggacgatatctcgactaac141106 tcgcgccagagccgcgaggcgatccgaatgcacgggtctaccgagtcggccgactccgac141166 gaggcgacagcggcaccttgccgcctgcgctcgccacgaggtaccgcgtgcgcagtaatg141226 tgatcgctgtccatcagcgccagcgggtagcacccgtcgagcatgttttccatttaggga141286 tgtgtctagaggagagcggtccgggcggtctactgcggttgtgctgggccgagttggacg141346 gctacggattgcgccgggcgtgaagggggggggggcggcgggatgtccggcggtcgcaaa141406 ggggcgcgcgtccgcttctgcgtgaaggctgagcgggaaagaagttctggatgagaatgg141466 atcgagcgggcaataaatgtccagagtaggggggtgggagggagggggaggttctgcccc141526 gcgtctcctctatctgctcgtcgaggcctcggccttgcgtcgccgtgcaggggtcgaggc141586 cgcttcttcttttttacttctctcctcggattcctcgtcagaggaagaagaaaatgacaa141646 cctccgtcttttaagagtgcgcctacccgccctggcggccgaagccttccgtgggtcttt141706 gcggggtgccgcgcaccgcaataacgcacggacgcgggggatagcaaatggcggcggcgc141766 cggagagctgtcgtcaataaagtctaagtcagattgcgtgggctctgactcggtggagct141826 gtgtcccgtgtcctcctcgcccaagtccactccccggcacccaggctgctcttcctccga141886 ctccgggtcgctccagctcctcccgcgtgccggttcttcgtcctccgatacgtccgaaaa141946 gaaaaacttctgggagagctcttcgggatcccagggaagctgctctggtgactttccgcg142006 gggcgacggataggtctcttctggcaagggagagggatcactcgacaaaggactgtggct142066 catatcttgcgcactgggtcttatttactcgtgttgtctttccgcagggaatgcgcggtt142126 cgagtaggccgtggtttgcggccgttctcggataagcacaaaatatcgccctactcgtgt142186 gtcaaaaaggaaaagtcttaatgggctgtgaagtgatctggagatcaaagcggcactctc142246 tttgagaagtctcttctcgagactctctcgagtcctaatgttaataactctggcagaggc142306 gcttcgttactgacgaagcttctgtgcatttatacgtgacgccacgctaacaaggaagcg142366 ccgcgcaatttgctcacggttgggcgtagctctgtcctcgagcgcacgcgaaaaattctc142426 gtctcatttccccttaccacaccacaccaaacactggtagtaaaatcgcataatgcaccc142486 caacgtcggaaacacagcccgagacgatgttgcttcttctttagggccccctctttttta142546 agctacaaaatttgctttgaggccttttcctttctttctttctttcgcgtgtgattgacg142606 ggggtttacgtgactaccttattagtcgtctcatatgcacggacacatcatgggctcagc142666 gctattaccctaggccgcttgtaattcgttgtctgtctacctgtctgtcaaattgtgact142726 accacgtaccaactcctccccaaagttctacccttttccttaaaaacacatttaaaatgt142786 caaaataccgatccttatatttgcgtgttatgttttcttttgccttctaggattgattga142846 attggaatgaaacgcaaaatcttggaataatgacggaacgcggatgcgaagaatctacaa142906 cgagacaggtcaatattttttcaaaaaaggtgttttattaaatctgctataccgctctta142966 tattaaagaaactttttatttattaaattgttgttaccccccaccgtagagcaagaccgt143026 gatgttctttacgccctcttctccggtcgttgtgttgtccatacatctcgtcttccctca143086 gcgctgcccgcaaatggttcaacgtatgtcggttggttgactatgtcctaatatcacttc143146 aagtttggcgcgcggacaaaatttaaactcaatattctcgcgccatattccattacaaaa143206 cgcgtgacctcgacaaaattcgggaaaatctaacagcattctatcttggagaatacgctc143266 ttgcgacagaccgtgggaaaaaattagaaaatttacccacggaccccagtcccgctttgc143326 cattttaggaaaatgttggaccctcggtgcgaacgtgacgtaggtgggtgccacccacat143386 catgtaaattaggtcacggggtaggattccggctccgcgattggttatgaggcccctaaa143446 gcaaacattcgcactccagtatttaatatattagggaaaacctaatatattaaatactgg143506 agtgcgaatgtttgctttaggggcctcataaccaatcgcggagccggaatcctaccccgt143566 gacctaatttacatgatgtgggtggcacccacctacgtcacgttcgcaccgagggtcctg143626 catcccccttccagccaatgagctgtgacttgcatcttcgggcactgcataaaagaacga143686 tccaggtcgctgtccccgcatatagcgggaccatcgggtcctgctcggattaccccagga143746 agaggggagaagatttcatactgggggcacaatgggatgggtcattgtcttctcacatga143806 gcaacccgaaaatccccccgccgatgcctccagaccacgccgacgcaggctccgtttaaa143866 gccatgcactgtcccagatggggatgggtcgccgatcggagaggcttgtcctcacgatac143926 acacgacccgggtcgagcacccccctcgacccccgaccctgaatgtgatcgggaagtgat143986 attcggcgggatgaactcatccggaggctgcgtgaccgatactctccaagacatcgcggg144046 ttaaaaatactctacgaaagctcatgttcgagtttacctgacccagaaaataaggaccca144106 acaaagtcgattgtcgtgaagagctagttaacactgaaccgccataggcgggtttgcact144166 ttatgaatttttgtttttacttgagccgttcggcatgtgccgggctcactactttatttg144226 ctctttaatagggccgctgagttgtttgggcccaccgacgtgcaggttatcggcttcgtt144286 gcccttgcttattgcatacatattgcatactttcatattactgctacgactgcgttgtaa144346 caccgtcagttaacacgattactgggtagatccagtatggatgtattacgcgcatgtata144406 tagcccgtaccttgatattataccggctattgcaactcgtgctttgtttcgagcgcatct144466 gctaagcctgcggctgcttccacgcgcagataactggttttagtcccacgggcaatccga144526 cataggtgcgtttcctaaaagaaacctgtagagacagtgccttgaccccccgacatatat144586 atctggaagtgtatttgcgattcaccggcgaatcggcaagtctcctgcggagaggctcct144646 gcgattacttccagatccgcgtaagaaaattacaggaacgtttgtaaatcgcaaaccaga144706 ttgcgaactatattcccgagcatggaccttctcgccatatctctcaaaagaagaaaagtg144766 ccctgcaaatacagaacgcatcccgagattcaaaatttgcgattcgtgcatcccgagcgg144826 caaatgtctcaataaagtaattatgtgttcccgcgaactactcgcgtggaacatggaacc144886 aagcttttgcgttgtctgaattttttatttaggctgggttagaggggtggctagaagata144946 ataatctttcgtggaaaattgctagagattagaacacacaagtaacacaagtgctcacgg145006 tgatatttacacatgtcaactctcccatatggggatcttttttctgtcacaacttccttg145066 gcactcccaggaagcgtgacccatgtgctttccttggcattcaaaataaacttcactgct145126 tcccggtgtggccaataacgtgcaagcgagcgtgtttctcgggtaatatcaatgccaaca145186 aaacacgcgtgacctttctagagtaggcacacaccccggcaccgaattgcacgcacctgt145246 ggacacaagcaatgtattgttttgttatcttcgtcatctgttctacagtaggctcaggtt145306 tgtttattatgttggctcataaaaaatgccggaagttcctggtacggtaatggtatgctg145366 ggcgcatggcatgcattggctatggcacaccggaactggaaatacgctcgctaacgatat145426 gcaggccgcatgggcgccattggatctgaattatatcatgcctcaatacaaatgccatac145486 ccaaaccaactgcacaagaccgaggggttgactctccaaagttctttcttcaccgtttgt145546 aaatcgcaaaccagattgcgaactatattcccgagcatggaccttctcgccatatctctc145606 aaaagaagaaaagtgccctgcaaatacagaacgcatcccgagattcaaaatttgcgattc145666 gtgcatcccgagcggcaaatgtctcaataaagtaattatgtgttcccgcgaactactcgc145726 gtggaacatggaaccaagcttttgcgttgtctgaattttttatttaggctgggttagagg145786 ggtggctagaagataataatctttcgtggaaaattgctagagattagaacacacaagtaa145846 cacaagtgctcacggtgatatttacacatgtcaactctcccatatggggatcttttttct145906 gtcacaacttccttggcactcccaggaagcgtgacccatgtgctttccttggcattcaaa145966 ataaacttcactgcttcccggtgtggccaataacgtgcaagcgagcgtgtttctcgggta146026 atatcaatgccaacaaaacacgcgtgacctttctagagtaggcacacaccccggcaccga146086 attgcacgcacctgtggacacaagcaatgtattgttttgttatcttcgtcatctgttcta146146 cagtaggctcaggtttgtttattatgttggctcataaaaaatgccggaagttcctggtac146206 ggtaatggtatgctgggcgcatggcatgcattggctatggcacaccggaactggaaatac146266 gctcgctaacgatatgcaggccgcatgggcgccattggttctgaattatatcatgcctca146326 atacaaatgccatacccaaaccaactgcacaagaccgaggggttgactctccaaagttct146386 ttcttcaccgtttgtaaatcgcaaaccagattgcgaactatattcccgagcatggacctt146446 ctcgccatatctctcaaaagaagaaaagtgccctgcaaatacagaacgcatcccgagatt146506 caaaatttgcgattcgtgcatcccgagcggcaaatgtctcaataaagtaattatgtgttc146566 ccgcgaactactcgcgtggaacatggaaccaagcttttgcgttgtctgaattttttattt146626 aggctgggttagaggggtggctagaagataataatctttcgtggaaaattgctagagatt146686 agaacacacaagtaacacaagtgctcacggtgatatttacacatgtcaactctcccatat146746 ggggatcttttttctgtcacaacttccttggcactcccaggaagcgtgacccatgtgctt146806 tccttggcattcaaaataaacttcactgcttcccggtgtggccaataacgtgcaagcgag146866 cgtgtttctcgggtaatatcaatgccaacaaaacacgcgtgacctttctagagtaggcac146926 acaccccggcaccgaattgcacgcacctgtggacacaagcaatgtattgttttgttatct146986 tcgtcatctgttctacagtaggctcaggtttgtttattatgttggctcataaaaaatgcc147046 ggaagttcctggtacggtaatggtatgctgggcgcatggcatgcattggctatggcacac147106 cggaactggaaatacgctcgctaacgatatgcaggccgcatgggcgccattggatctgaa147166 ttatatcatgcctcaatacaaatgccatacccaaaccaactgcacaagaccgaggggttg147226 actctccaaagttctttcttcaccgtttgtaaatcgcaaaccagattgcgaactatattc147286 ccgagcatggaccttctcgccatatctctcaaaagaagaaaagtgccctgcaaatacaga147346 acgcatcccgagattcaaaatttgcgattcgtgcatcccgagcggcaaatgtctcaataa147406 agtaattatgtgttcccgcgaactactcgcgtggaacatggaaccaagcttttgcgttgt147466 ctgaattttttatttaggctgggttagaggggtggctagaagataataatctttcgtgga147526 aaattgctagagattagaacacacaagtaacacaagtgctcacggtgatatttacacatg147586 tcaactctcccatatggggatcttttttctgtcacaacttccttggcactcccaggaagc147646 gtgacccatgtgctttccttggcattcaaaataaacttcactgcttcccggtgtggccaa147706 taacgtgcaagcgagcgtgtttctcgggtaatatcaatgccaacaaaacacgcgtgacct147766 ttctagagtaggcacacaccccggcaccgaattgcacgcacctgtggacacaagcaatgt147826 attgttttgttatcttcgtcatctgttctacagtaggctcaggtttgtttattatgttgg147886 ctcataaaaaatgccggaagttcctggtacggtaatggtatgctgggcgcatggcatgca147946 ttggctatggcacaccggaactggaaatacgctcgctaacgatatgcaggccgcatgggc148006 gccattggttctgaattatatcatgcctcaatacaaatgccatacccaaaccaactgcac148066 aagaccgaggggttgactctccaaagttctttcttcacaacacctttgctgaaacctacc148126 cagcgtggaaaggacctcttcgcaaaacgtaagtcatgaaaccaatattctgttataaat148186 tttggggtgggattaggtgggctgtcattatttgaggggaccacgaaatatccttttgca148246 tggggtatcgtgcaaaaatatgactgtgggcttcgaataattcccccatacagtcaagag148306 tatgggctgctgttatggatgaacatgaagcgcacaaaacgataatccacttctttagca148366 tgtattgctgttccaaaattgtgcctatggttgcggagctttattgtgctctgcattgcg148426 gggacggaaataaacaggccaacgcgagaaacgggaggtttcgagagtcgcgcatcttta148486 ttttttctgttactactccccaccagaaagcttcacgtttcttccaacttctgcacaaaa148546 cttacgtaaccttgtcactcgggtcttgttctgcaggattctggaaatcgctagtccttc148606 cactagcattctatcatgtcctctgattcctcgacgccgagtaatttggccgctccaatt148666 gttgatgagtcgggattctcaactggcccgccctcagatctatttacctttttgcgcgcc148726 gataagagtgggcgctacgattctttgggttctcccatcccgaaccctccaaacgcacct148786 acctgtgagaccactactgatagcttttcgtacagcacgccacctcttttttccagcgag148846 gacgagctctttcactctgtcatcgctgagaatgcggcccaagacgcggcccaagacgtg148906 gacgggcgagaaatgtctctccgcgaccttatagcgatgttaaacgacatggatcccgaa148966 aacataaactctatagaaccgtgtccgaacgctaccagtgatgtcgtggcactagatatt149026 aacgtggataccgatcagcccggagtttatacggtcatcgactcgctcgcacatccctgc149086 gaaactcccatggagcagcagcacgttgaatgcccgtgtccattacctgcagtagagaaa149146 acaaccgctgtgaggcgtcaagaagtggtgaggaagtcagagagagtggccagatctcgt149206 tcgcgacgcgccgtggcgcgatctttgagcaaccggcgccccgtcccttcgccgcagagg149266 accagcaaagaccgtctccccaagcgagggaagagggaattttcgaagaagatgggcccg149326 agccaccttacctcttcctcctcttcctcctcttcctcattctcgctgtcagggaggagg149386 ggacgtctcgcccgaaggctggaaagcgcgggaagtgaaaaatccgccgaaagccccgac149446 cgggactctgcccaattagtgctacctggagaatgtcccgatgtcgcgctagagccactc149506 tggcgagttttgagggagtgggtcgaaacggacggtacagacgggtcggttcagtcagta149566 accgcgcctacggagctcccagacctaggccgcggcattaccctgaatgtactctcacga149626 gcgttggccgtcgacctccatagttccgaggctcgcgtttttgttccagaagctattatc149686 ccgtccccacccagtagaggacaagtatatcatggaagtggctatagacagtctttggtc149746 gatgacccgcaggttcgggaggccgcggccgaattccatgccaatccgaaatcagcttcc149806 gtgtatctcgaagagtacgggatgccagtggaacagttagagcgccttgtggaggagttc149866 atggtccagcccctgtcgcgcgtttcgtatgggtatggcggccccaagctgagcccacgt149926 gacaaacggctctgcgaactgtgcgctctccgcggtccgggttcttccgagggaggattg149986 tctcgttctgcggtgccgacgtgcctcccgcacgtagcgcacgccatgcgtgatggccgt150046 gtgtcattagctctgccgcaccttaccgagctcgtacgcgtgtgccgccgctatgaccat150106 ccgcagaaaacttacctgttggcggctcttaggagagcgtttgtcccgtttgtatttcca150166 ggagcggccgtggatcctacggcggcgtctgcttctggggaccaccctgtactcgttggc150226 gccaggcgaatagcgcgtgccacgagggagctggaagccgcagcgaaagagccacctgcg150286 gcaaccccggaaaaactttcctcttcggcgctattgcgccatactagaacttgcattgtt150346 gctgccgcagatctcatggcggcgcttactgctatagactgcccaccagttacaataaac150406 cccgccaagcgtcgcccggatctgtatcaagcactctcgagggcgcccaaaacagtcttt150466 acgtgggagcgcgccatgcgctactgcgcggcttcgctatggagtcgcctcgtcataggg150526 tccctgccgctgccatctaccgatgatgtcactcttcttgtagaagccatggaagctgcc150586 gtgggcgtgcttggctgctccgacgagggtgacgtgcggccttcaattgcctacgcggcc150646 tctggttggaggatgatcgctaccatgctaggagatgattccgcgcccggcagcgagcac150706 gtcacggacgattgtcccgcagatgatgacacccaccaccatgacaggcgcaaaagacga150766 ggcggccggcggagcacttgccggtacgacctacctcctggcactcccgatcgcgcggcc150826 cacctcctactctacgggagtcctggcggcggcaacggagcagagccttcggctgcccaa150886 gaatctcccgccaacccctggcccagagctccaccgtgcgatgaacaggagccattatct150946 gtgtcaccgtacgggcccgaacccgaccgccctccagatgatgactttgagacccgtaaa151006 ggtctgaaaagaaagtcatctgaagatcacgcggacccgatcccagaaggcaacgcgact151066 aaaaaaacatgtggcctccagggcttaccagattcattacctccagcggttccagaaaca151126 gatagagacaacctcctcctttcgccatgccccataactcccgagggtccaccatgtccg151186 ccccgagaagaaccgcaagaaccacaatccccgtcctttcacatttccgagataggtgag151246 gccctgtttcattctaccccaatcagccctaccatcctgttcgcaccggagggtttcatc151306 ccgaaccaaggggatgtttaccgtccccatggcaaaaacttgggcgttgcgctctccgca151366 ggggagccatacgtgcccgcccatcgcgcgcgtcctgctttggagcggctcgcgaactat151426 ttgcgcgggttgagcagcggtccggcgggaagctattccgcgaccggacccgcagattgg151486 ctacctgcttttgcgagggacccagtagccctgggggagttttgcaagaggatttcaccc151546 gtgaacagaggggggcgctgcgtcttagaggagcggctttcctggacgttgcgacatccg151606 gctgacaaaatctatgacctcatcattcttgtctcagaacgtgccccgggcgaattttta151666 gaacgcgcgtacgcctacgcggccctctgcggacgtgcctgcatgccgggcggtgcctgt151726 tggccagaatcgtggacacgcggggagtatccctatatccctcccgacgagaaagacccg151786 ggccgcagcgtggccattctctgtacgacagaccttggatacgccggggcggtagaatgg151846 atgcttgagcgcgctctcagtacatctgggcgcgcatgcgtggtcgtagatgctagggat151906 cccggggacgaggattcccgctcgggtccgcgcatacctaccgggcggaggggtgttgtc151966 tatgcccggactagccccccgtcgcacgcttaccttgtaaaactgtttaccggtccggcg152026 gccgaacggttggaacggggtgggctcaatgtaggtcacgtagtaatggacaggcgactc152086 actgtctcatggcccctcagcgttgggaagaccgacaacgacgatgagggtacaggagac152146 agagagaagtgtcctcccgttaagcaccccttcctcactcacgtaactctcaggagatta152206 cgcgacgttgctcgtgccatggatgccgggtggagccactccgaaatcggaaaagcttca152266 gccgtcttgtatccgtacatggcccagccccatgtgggcgccggggcgatgccgccatgt152326 ccggacctttccgagtccagttccactatgcattcttcttcgtcgtcttcctcttcctca152386 tgctcctcgtcgtcgtcttcttcagactccagctcatctgaagaagacggggacgagaag152446 aacgagaaagaagatcgtgagcgcgccggaggtggaaagcggcgcggccgccagcgcctc152506 ccgattcgggaccgcgtgtaccgtggccgggactaccgcgtgcgcactccctgtgctgat152566 attgtgggaggcacttctgcttcctttagggccgtcgctgcgtgggggggggacacggta152626 attcccgccctccctctcgcagcgtcctggtccgatcccagcaaaattccacaggaagtt152686 ctccgcatcatctccgattattacccggatgcgccaggggcgcgggcgcgtcggaacccg152746 cttcacgtggaaggactagcgcttatgcgtgccagaaatcccgcccctctcgcattgcta152806 cttggtgacgactattcccattatcacactccccgcaatcggtccccaatgtgttgttgc152866 tggagtgctccgcggggagcaacgccagagtcacccagatgcaccggacacacgcgcacc152926 aggcgcccaaggctaaccgtctcctcagggaggggggaaactagaacccttgtacccaga152986 ttagactcttcagaggataggcggtcgcgtcaacgccatagacgcatgactaactaccct153046 ctaccgcatcccactgtcactgacccttggtggtaaccgtggtttccgttattaacttaa153106 cttattaaaactttttgtacaatttacttctggttgcgtgctcattcttttgctagtcgg153166 agcttgtcagccaccgacgacttgtagaaaaagaccggggaaatgatctagccccgttga153226 ctttagctttgctgaacattctacccgtgcggccatggagtgatattagaaaagggacga153286 gaatgggggcaagtacgaatatcgggaggaggcggaacgaggtgttaagtaatgcacttg153346 aatatttaattcgttcattttgatacataagatccacggaagcttgtaatgctggccggc153406 agcattattactattgcaagcgccgatataaaaatcgcaatcaaaatactagattgtcta153466 gtattgcctgctctgacggacgtaacgtctctgtagggcgttcgccaggtcattcaggaa153526 cgacttcatcaaatacgaatcctccactgttatagggcacggtgcctgtaataaatagga153586 gatacaatgttagactcgtcatgcgaccaataaggaccgcgtgagcacggagacaaaaga153646 tgtctcggagatactgtgctgcgcgttagatagtctcttcaaagtacagaatgcgcgatg153706 ctgccattatcttaccttgcgagagctaccgccattactgacagaattcagcacgtaata153766 caaattgacgtagagcccctgcagttttttgtgacactgttggtgtttcaaaatgaccga153826 aagggattggcacaactcttcagtttcgtttagacgctgcaggaaaagcaagattcgtta153886 ataaaccgccgagcagattattgggcagggtagacctaagcaaaaaatctacatttttaa153946 tctggggctagcgcgcggccggcctccagggcattgccgttgagaacatgtgacaaatga154006 gctggcttttactcaccgtgtcggacgtaaagatgttcggaactcttctaccgtcgcagg154066 aacccttataaggaaacgagagagcctacagttatgaacgtgaacatagactgaatagcc154126 gtacatagttacaaagaccgtgcaggcatgtcagcatggtccaacgagaatgagttgcct154186 tacgtccttctgcacacggtgcagtattctgatgctctccgccagtaacttcaagggtgc154246 cgcgcgtatactgcgagcatccccgactccaagtagtaacaccagtaacgccagtgcggc154306 ggacaatggaggcttcgacttgccaggcattcccaccgcgcgcaaccgccgccgcgaaac154366 ttctcccctagttctccctctgggttcttccctaaggatacactgccaccatttatatag154426 ctttacgtggcgggaaagccctagcccccactatacccggaagcggctacactagagccc154486 ttgcaagagcagaaaattttcccgccgtgggttgcgcgtgaacaacttaccagaacgaga154546 atttttgaaacctctgagactcacagcacgtgcttacgaataccagaaactgggagcacg154606 gtgcttccgcgacactctacaaagataagtgcgggcacagttaggtgctactgcgcttag154666 ctaagtgcttaacctgagtagcacctaattgcggccttaggccaaggtgtcgttacccgg154726 atagctttcacatcgatagcgcgtattaccttcggcctgacaactgtcagctacccaacc154786 gctctgtcttctttcaatccttgactattataactcgcggtaaccggccgtggccacata154846 gtgaggcggttatacggaataagacccccccccccggggccttcacgttcgtgtccgttc154906 ttgccagtgagcgttgctggaaatcgaaaattccagtgtggcgcttattgtgcaagaacc154966 acgggcgtgacctgtatgactactgagcaaagcacctcgcgctgccgcgaaacttacaaa155026 cggggcgaactgcgtgacgattctgtgatcgcgcttcgaggtccagtcggagcccaccgg155086 tgcccacctgaaccttttcagctccggaaaaggctaaactggaaaatctagtagaactag155146 tttcacggctgcccgcgctgaccgtttgctctccacgggtggaagaacttgggggggggg155206 gttggcggacgctggcgtttgatgtcgggccgtcaagtatctcgcaaccccagaacctgt155266 ccagcatctaatagtaggggtcggacatgaaaccacaagggattggaagggcggggagca155326 ctcaggggactgggaggggacgggtcggagaaaaccgcggaccaccagtgcacacaccct155386 gcatccttggctgctcatatatagcccccccccgcaaaacacccccccgggtttattgcc155446 gacgacggggctgtggagc155465