AN EXPANDABLE PLUG BODY FOR USE IN VAGINA AND ITS APPLICATION

Abstract

The present invention relates to an expandable plug body for use in a vagina which is expandable at a predetermined value in an aqueous solution and has an expansion value of 1 to 30 at saturated water absorption. Effective components may be immersed in the interior of the expandable plug body, or dissolved and dispersed in the material wrapping the expandable plug body. The expandable plug body is primarily used in the vagina. The present invention provides an expandable plug body having some unique physical properties such as expanding at a predetermined expansion value, expanding at a specific pH value, and periodically expanding, so that it has a good performance when used as a medicine, a cosmetic, and a disinfection product. After the application of the original liquid of the expandable plug body onto the vagina for 35 min, antibacterial rates of which on E. coli, Staphylococcus aureus and Candida albicans are all in the range of 8995%.

Claims

1.-10. (canceled)

11. An expandable plug body for use in a vagina, wherein keels are provided on the surface of the expandable plug body in axial or radial direction, wherein 3-5 keels are provided in the radial direction and 8-10 keels are provided in the axial direction.

12. The expandable plug body for use in a vagina of claim 11, wherein the outer periphery of the expandable plug body is wrapped with a non-woven fabric as a protective layer; the nonwoven fabric is any one or a mixture of at least two selected from the group consisting of polyester fiber, polyolefin fiber, polyamide fiber, polyacrylonitrile fiber or regenerated fiber.

13. The expandable plug body for use in a vagina of claim 12, wherein the nonwoven fabric is any one or a mixture of at least two of polypropylene fiber, polyester fiber, polyamide fiber, viscose fiber, acrylic fiber, polyethylene fiber or polyvinyl chloride fiber.

14. The expandable plug body for use in a vagina of claim 11, wherein the expandable plug body comprises a high expansion zone and a low expansion zone.

15. The expandable plug body for use in a vagina of claim 14, wherein the expansion value of the high expansion zone is 20-30; and the expansion value of the low expansion zone is 1-10.

16. The expandable plug body for use in a vagina of claim 14, wherein the material for preparing the high expansion zone comprises at least cellulose fiber, cotton and viscose fiber; and the mass ratio of the cellulose fiber, cotton and viscose fiber is 7-10:1-2:1-3.

17. The expandable plug body for use in a vagina of claim 14, wherein the material for preparing the low expansion zone comprises at least cellulose fiber, cotton and viscose fiber; and the mass ratio of the cellulose fiber, cotton and viscose fiber is 4-6:3-5:1-2.

18. The expandable plug body for use in a vagina of claim 11, wherein different parts of the expandable plug body have same expansion value but different expanding orders.

19. The expandable plug body for use in a vagina of claim 18, wherein the outer end of the expandable plug body firstly expands.

20. The expandable plug body for use in a vagina of claim 11, wherein different parts of the expandable plug body have different expansion values.

21. The expandable plug body for use in a vagina of claim 20, wherein the expansion value of the keel is larger than that of the other parts.

22. The expandable plug body for use in a vagina of claim 11, wherein the expandable plug body has a diameter of 3-15 mm, a weight deviation of 1 to 4 g, a length of 10-60 mm, and a pull wire length of 50 mm.

23. The expandable plug body for use in a vagina of claim 22, wherein the expandable plug body has a diameter of 10-11 mm, a weight deviation of 2.1-2.4 g, a length of 43-46 mm, and a pull wire length of 100 mm.

24. The expandable plug body for use in a vagina of claim 11, wherein the interior of the expandable plug body is provided with a built-in expandable plug body which will expand after the expandable plug body exerts its expansive action.

25. The expandable plug body for use in a vagina of claim 24, wherein the built-in expandable plug body is at least 2.

26. The expandable plug body for use in a vagina of claim 25, wherein the built-in expandable plug body is 3-5.

27. A product containing the expandable plug body for use in a vagina of claim 11, wherein the product is a drug, a cosmetic, or a disinfection product.

28. The product of claim 27, wherein the expandable plug body is used in a cosmetic.

29. The product of claim 28, wherein the cosmetic is made by immersing the expandable plug body in a cleaning agent; the cleaning agent comprises the following raw materials in parts by weight: 30-60 parts of liquid paraffin, 10-40 parts of lanolin, 10-40 parts of olive oil, 0.01-10 parts of carbomer, and 0.01-10 parts of hyaluronic acid.

30. The product of claim 29, wherein the cleaning agent comprises the following raw materials in parts by weight: 44 parts of liquid paraffin, 27 parts of lanolin, 28 parts of olive oil, 0.5 part of carbomer, and 0.5 part of hyaluronic acid.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0034] FIG. 1 is a schematic diagram of the structure of the expandable plug body for use in a vagina according to the present disclosure, wherein 1 represents radial keel and 2 represents axial keel.

[0035] The present disclosure will be further described in detail below. However, the following examples are merely illustrative examples of the present disclosure, which do not represent or limit the claimed scope of the present disclosure that is only defined by the claims.

DETAIL DESCRIPTION

[0036] The technical solution of the present disclosure will be further described below by way of specific embodiments in combination with accompanying drawing.

[0037] FIG. 1 shows the expandable plug body for use in a vagina according to the present disclosure which is provided with a keel 1 in the radial direction, and a keel 2 in the axial direction, on the surface of the body.

[0038] In order to better illustrate the present disclosure, and easily understand the technical solution of the present disclosure, the typical but non-limiting examples of the present disclosure are as follows:

Example 1 Bacteriostatic Maintenance Agent

[0039] The expandable plug body for use in a vagina of this example was made of cellulose fiber, jute and viscose fiber as materials in a ratio of 5.5:2:1, wherein the cellulose fiber was supplied by Shanghai Royang Innovative Material Technologies Co., Ltd. 3 keels were arranged in the radial direction, and 8 keels were arranged in the axial direction, on the surface of the body, the pull-out end firstly expanded, the expansion value of the pull-out end and the incoming end were the same; one end of the expandable plug body was provided with a cotton string, wherein a nonwoven fabric material of polypropylene fiber was used as the protective layer.

[0040] The active ingredients carried by the expandable plug body were chlorhexidine acetate and chitosan in a weight ratio of 100:100, and fillers of algal polysaccharide and liquid paraffin.

[0041] In this Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were all 92% upon detection after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

Example 2 Bacteriostatic Maintenance Agent

[0042] Compared with Example 1, Example 2 was the same as Example 1 except that 4 keels were arranged in the radial direction, and 9 keels were arranged in the axial direction, on the surface of the body.

[0043] In this Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 94%, 92.4% and 92.5%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

Example 3 Bacteriostatic Maintenance Agent

[0044] Compared with Example 1, Example 3 was the same as Example 1 except that 3 keels were arranged in the radial direction, and 9 keels were arranged in the axial direction, on the surface of the body.

[0045] In this Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were all 93% after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

Example 4 Bacteriostatic Maintenance Agent

[0046] Compared with Example 1, Example 4 was the same as Example 1 except that 3 keels were arranged in the radial direction, and 10 keels were arranged in the axial direction, on the surface of the body.

[0047] In this Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 94.8%, 94.9% and 95%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

Comparative Example 1 Bacteriostatic Maintenance Agent

[0048] Compared with Example 1, Comparative Example 1 was the same as Example 1 except that 8 keels were arranged in the radial direction, and 3 keels were arranged in the axial direction, on the surface of the body.

[0049] In this Comparative Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 65%, 58% and 62%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

[0050] By comparison between Example 1 and Comparative Example 1, it can be concluded that when more keels are arranged axially and relatively less keels are arranged radially, it can help the active ingredients to function better, so that the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans can be greatly increased.

Comparative Example 2 Bacteriostatic Maintenance Agent

[0051] Compared with Example 1, Comparative Example 2 was the same as Example 1 except that 1 keel was arranged in the radial direction, and 8 keels were arranged in the axial direction, on the surface of the body.

[0052] In this Comparative Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 67.5%, 60% and 68%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

[0053] By comparison between Example 1 and Comparative Example 2, it can be concluded that when the same number of keels is arranged in the axial direction, but the number of keels in the radial direction is reduced, it will delay the expansion of the expandable plug body to a certain extent, resulting in uneven expansion, so that the active ingredients cannot fully act on the subject, thereby reducing its efficacy.

Comparative Example 3 Bacteriostatic Maintenance Agent

[0054] Compared with Example 1, Comparative Example 3 was the same as Example 1 except that 3 keels were arranged in the radial direction, and 5 keels were arranged in the axial direction, on the surface of the body.

[0055] In this Comparative Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 67%, 67.8% and 70%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

[0056] By comparison between Example 1 and Comparative Example 3, it can be concluded that when the same number of keels are arranged in the radial direction, but the number of keels in the axial direction is reduced, likewise it will delay the expansion of the expandable plug body to a certain extent, resulting in uneven expansion, so that the active ingredients cannot fully act on the subject, thereby reducing its efficacy.

Comparative Example 4 Bacteriostatic Maintenance Agent

[0057] Compared with Example 1, Comparative Example 4 was the same as Example 1 except that 6 keels were arranged in the radial direction, and 12 keels were arranged in the axial direction, on the surface of the body.

[0058] In this Comparative Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 70%, 65.1% and 68.4%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 3 minutes.

[0059] By comparison between Example 1 and Comparative Example 4, it can be concluded that when more keels are arranged radially and axially, it will make the expansion degree of the vector to be difficult to control, resulting in uneven expansion, likewise it will reduce the efficacy of the active ingredients.

Example 5 Bacteriostatic Maintenance Agent

[0060] Compared with Example 1, Example 5 was the same as Example 1 except that the polyamide fiber was used as the nonwoven fabric material.

[0061] In this Example, the antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 89%, 92% and 94%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 4 minutes.

Example 6 Bacteriostatic Maintenance Agent

[0062] Compared with Example 1, Example 6 was the same as Example 1 except that the acrylic fiber was used as the nonwoven fabric material.

[0063] The antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 92%, 93.1% and 94.2%, respectively after the stock solution carried by the bacteriostatic maintenance agent acted in the vagina for 5 minutes.

Example 7 Cleaning Product

[0064] On the surface of the expandable plug body for use in a vagina of this Example, 3 keels were arranged in the axial direction, and 10 keels were arranged in the radial direction, and the segment contained keels were the high expansion zone, the remainders were the low expansion zone. The materials for preparing the high expansion zone of the expandable plug body comprised cellulose fiber, cotton and viscose fiber, and the ratio of the cellulose fiber, cotton and viscose fiber was 7:1:1; and the materials for preparing the low expansion zone of the expandable plug body comprised cellulose fiber, cotton and viscose fiber, and the ratio of the cellulose fiber, cotton and viscose fiber was 4:3:1. The cellulose fiber was supplied by Shanghai Royang Innovative Material Technologies Co., Ltd. The pull-out end and the incoming end simultaneously expanded, but the expansion values of the both were different.

[0065] In this Example, the active ingredients carried by the expandable plug body were 44% of liquid paraffin, 27% of lanolin, 28% of olive oil, 0.5% of carbomer and 0.5% of hyaluronic acid.

[0066] The antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 92.5%, 92.8% and 95%, respectively after the stock solution carried by the cleaning product acted in the vagina for 3 minutes.

Example 8 Cleaning Product

[0067] On the surface of the expandable plug body for use in a vagina of this Example, 3 keels were arranged in the axial direction, and 10 keels were arranged in the radial direction, and the segment contained keels were the high expansion zone, the remainders were the low expansion zone. The materials for preparing the high expansion zone of the expandable plug body comprised cellulose fiber, cotton and viscose fiber, and the ratio of the cellulose fiber, cotton and viscose fiber was 8:2:1; and the materials for preparing the low expansion zone of the expandable plug body comprised cellulose fiber, cotton and viscose fiber, and the ratio of the cellulose fiber, cotton and viscose fiber was 5:5:2. The cellulose fiber was supplied by Shanghai Royang Innovative Material Technologies Co., Ltd. The pull-out end and the incoming end simultaneously expanded, but the expansion values of the both were different.

[0068] In this Example, the active ingredients carried by the expandable plug body were 30% of liquid paraffin, 38% of lanolin, 15% of olive oil, 10% of carbomer and 7% of hyaluronic acid.

[0069] The antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans were 91.0%, 90.8% and 92%, respectively after the stock solution carried by the cleaning product acted in the vagina for 3 minutes.

[0070] In conclusion, an expandable plug body for use in a vagina is provided in the present disclosure, the active ingredients of which can immerge into the interior of the expandable plug body, or dissolve and disperse in the materials wrapping the expandable plug body. The antibacterial rates against Escherichia coli, Staphylococcus aureus and Candida albicans are between 89% and 95% after the stock solution in the expandable plug body acts on the vagina for 3-5 minutes; therefore it has important application value.

[0071] Applicant has stated that although the detailed structural features of the present disclosure have been described by the above embodiments in the present disclosure, the present disclosure is not limited thereto, that is to say, it is not meant that the present disclosure has to be implemented depending on the above detailed structural features. It will be apparent to those skilled in the art that any improvements to the present disclosure, equivalent replacements to the selected components in the present disclosure, additions of ancillary components and choices of specific embodiments etc., all fall within the protection scope and the disclosure scope of the present disclosure.

[0072] While the preferred embodiments of the present disclosure are described in detail hereinbefore, the present disclosure is not limited to the specific details in the above embodiments, various simple variations of the technical solution of the present disclosure can be made within the scope of the technical concept of the present disclosure, and these simple variations fall within the protection scope of the present disclosure.

[0073] Additionally, it is to be noted that the specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction with the present disclosure, and in order to avoid unnecessary repetition, various possible combinations will not be described in the present disclosure.

[0074] In addition, any combination of the various different embodiments of the present disclosure may be made as long as it does not deviate from the spirit of the present disclosure and should likewise be regarded as the disclosure of the present invention.