Stirrer installation aid and method for installing a stirrer element in a bioreactor

Abstract

A bioreactor has a stirrer shaft that is driveable by a drive and on which a stirrer element is positioned. The position of the stirrer element is determined by a stirrer installation aid. The stirrer installation aid has a free end with an abutment surface on which the free end of the stirrer element abuts. The stirrer installation aid is designed as a sleeve that comprises a slot extending between the axial ends of the sleeve. The slot is delimited by opposite flanks of a wall, and the sleeve is placed on the stirrer shaft. The stirrer installation aid can be pulled off laterally from the stirrer shaft. A method for installing the stirrer element on the stirrer shaft arranged in the bioreactor also is provided.

Claims

1. A bioreactor comprising: a stirrer shaft (4) that is driveable by a drive (5); a stirrer element (7) positioned on the stirrer shaft (4); and a stirrer installation aid (11) defining a sleeve (12) having opposite inner and outer surfaces and opposite first and second axial ends (14, 13), the sleeve (12) being mounted on the stirrer shaft (7) so that the inner surface faces and extends partly around the stirrer shaft (4), the second axial end defining an abutment surface (22) on which the stirrer element (7) abuts, the stirrer installation aid (11) having a slot (15, 15, 15) extending from the inner surface to the outer surface and from the first axial end to the second axial end (13, 14) of the sleeve, the slot (15, 15 15) being delimited by opposite flanks (16, 16, 16, 17, 17, 17) of a wall (18, 18, 18) that forms the sleeve (12), and the opposite flanks (16, 16, 16, 17, 17, 17) of the slot (15, 15, 15) being spaced from one another to define a slot width that enables the stirrer installation aid (11) to be pulled off laterally from the stirrer shaft (4).

2. The bioreactor of claim 1, wherein the stirrer installation aid (11) is placed on the stirrer shaft (4) so that a first axial end (14) of the stirrer installation aid (11) abuts on a mounting surface of the bioreactor (1), and the slot (15, 15, 15) being dimensioned to permit the stirrer installation aid (11) to be removed laterally after the stirrer element (7) has been fastened to the stirrer shaft (4).

3. The bioreactor of claim 2, wherein the stirrer installation aid (11) is made of an elastic material and is expandable to widen the slot (15, 15, 15).

4. The bioreactor of claim 3, wherein the stirrer installation aid (11) has a C-shaped cross section.

5. The bioreactor of claim 3, wherein the stirrer installation aid (11) has a U-shaped cross section.

6. The bioreactor of claim 2, wherein the sleeve has a length determined by a spacing of the axial ends (13, 14) and determines a position of the stirrer element (7) on the stirrer shaft (4).

Description

BRIEF DESCRIPTION OF THE DRAWINGS

(1) FIG. 1 is a lateral, partially sectional, view of a bioreactor with a stirrer having a stirrer element, the position of the latter on the stirrer shaft being determined by an installation sleeve.

(2) FIG. 2 is a lateral detail view of a bioreactor with a stirrer shaft.

(3) FIG. 3 is a lateral detail view of the bioreactor from FIG. 2 with a stirrer installation aid.

(4) FIG. 4 is a lateral detail view of the bioreactor from FIG. 3 with a stirrer element in place.

(5) FIG. 5 is a lateral detail view of the bioreactor from FIG. 4 from which the stirrer installation aid has been removed.

(6) FIG. 6 is a lateral view of a stirrer installation aid.

(7) FIG. 7 is a cross section of the stirrer installation aid from FIG. 6, cut along Line VII-VII.

(8) FIG. 8 is an additional cross section of a stirrer installation aid according to the cross section from FIG. 7, also with a C-shaped design.

(9) FIG. 9 is a cross section of an additional stirrer installation aid with a U-shaped design.

(10) FIG. 10 is a lateral detail view of an additional bioreactor, with a stirrer element, stirrer shaft and stirrer installation aid arranged in suspended configuration.

(11) FIG. 11 is a lateral, partially sectional, view of a bioreactor with a stirrer having stirrer elements, the position of the latter on the stirrer shaft being determined by installation sleeves.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

(12) A bioreactor 1 basically consists of a reactor interior 2 with a stirrer 3.

(13) The stirrer 3 consists of a stirrer shaft 4 extending into the reactor interior 2, the stirrer shaft 4 being driveable by a drive 5, e.g. a motor, and having a stirrer element 7 positioned at its free end 6 facing away from the drive 5. In the exemplary embodiment shown in FIG. 1, the stirrer element is fixed to the stirrer shaft 4 with a screw 8. The stirrer element 7 consists of a ring-shaped connector 9 that can be placed on the free end 6 of the stirrer shaft and radially extending stirrer paddles 10. A stirrer installation aid 11 is placed on the stirrer shaft 4, said stirrer installation aid 11 being designed as a sleeve 12 with a slot 15 extending between its axial ends 13, 14. The slot 15 is delimited by the opposite flanks 16, 17 of the wall 18.

(14) The position of the stirrer element 7 on the stirrer shaft 4 is predetermined by the sleeve 12, which is used as a stirrer installation aid 11 and whose second or upper axial end 13, in the installation shown in FIG. 1, is abutted by the stirrer element 7 and its connector 9. The sleeve 12 is designed to be elastic, i.e. flexible, so that its slot 15 can be expanded to such an extent that it can be both laterally placed onto and laterally removed from the stirrer shaft 4.

(15) The reactor interior 2 is delimited laterally by a reactor wall 19, by a reactor floor 20 in the downward vertical direction, and by a reactor ceiling 21 in the upward vertical direction.

(16) In order to position the stirrer element 7 on the stirrer shaft 4 (see FIG. 2), in a step a) the stirrer installation aid 11/sleeve 12 is placed on the stirrer shaft 4, whereby its lower or first axial end 14 abuts on the adjacent reactor floor 20 (see FIG. 3), for example. In a subsequent step b), the stirrer element 7 is placed with its connector 9 on the free end 6 of the stirrer shaft so that its abutment surface 22 abuts on the upper or second axial end 13 of the sleeve 12. In a step c), the stirrer element 7 is fixed to the stirrer shaft 4 by the screw 8 (see FIG. 4). In a subsequent step d), the stirrer installation aid 11/sleeve 12 is then removed from the stirrer shaft 4 by pulling it off laterally.

(17) To install multiple stirrer elements 7, 7 on the stirrer shaft 4 arranged within the bioreactor 1 (see FIG. 11), at least one further stirrer element 7 is installed on the stirrer shaft 4 arranged within the bioreactor 1 following installation of the first stirrer element 7, with the following steps being carried out: a) placing a second sleeve 12 which is slotted in the axial longitudinal direction over the entire length of the sleeve, which sleeve also forms a stirrer installation aid 11, on the first stirrer element 7 fixed to the stirrer shaft 4, b) placing a second stirrer element 7 on the free end of the stirrer shaft 4 until it abuts on the adjacent end of the second sleeve 12, c) fixing the second stirrer element 7 on the stirrer shaft 4, d) removing the second sleeve 12.

(18) If necessary, in a step e), the steps a) to d) are repeated multiple times to fix additional stirrer elements 7, 7 to the stirrer shaft 4.

(19) The cross section of the sleeve 12 can be designed in a C shape according to FIGS. 7 and 8. The width of the slot 15, 15 formed by the space between the opposing flanks 16, 17 and 16, 17, respectively, depends in particular on the elasticity of the sleeve material. In principle, however, the cross section of the stirrer installation aid 11 can also be designed in a U shape, and the space between the opposing flanks 16, 17 of the slot 15 corresponds approximately to the interior diameter of the sleeve 12.

(20) Although the stirrer element 4 is arranged upright in FIGS. 1 to 9 and 11, it can also be arranged in a suspended configuration, as per FIG. 10.

(21) Of course, the embodiments discussed in the specific description and shown in the figures are merely illustrative exemplary embodiments of the present invention. In light of the present disclosure, a person skilled in the art has a broad spectrum of optional variations available. In particular, the stirrer element 7, the stirrer shaft 4 and the stirrer installation aid 11 can also be arranged in a suspended configuration on the bioreactor 1 or they may be arranged laterally on the reactor wall 19. At a minimum, the stirrer installation aid 11 should be designed so that it at least partially encloses the stirrer shaft 4, can exert a firm clamping action, and can be removed laterally.

LIST OF REFERENCE NUMBERS

(22) 1 Bioreactor

(23) 2 Reactor interior

(24) 3 Stirrer

(25) 4 Stirrer shaft of 3

(26) 5 Drive

(27) 6 Free end of 4

(28) 7, 7 Stirrer element

(29) 8 Screw

(30) 9 Connector of 7

(31) 10 Stirrer paddle of 7

(32) 11 Stirrer installation aid

(33) 12, 12 Sleeve

(34) 13 Second axial end of 12

(35) 14 First axial end of 12

(36) 15, 15, 15 Slot of 12

(37) 16, 16, 16 Flank of 12

(38) 17, 17, 17 Flank of 12

(39) 18, 18, 18 Wall

(40) 19 Reactor wall of 1

(41) 20 Reactor floor of 1

(42) 21 Reactor ceiling of 1

(43) 22 Abutment surface of 9