PLANT BASED SUPPLEMENT COMPOSITIONS

Abstract

A composition comprising, for example, 1 wt-% to 10 wt-% curcumin or turmeric; 50 wt-% to 60 wt-% ginger; 10 wt-% to 20 wt-% ashwagandha; and 25 wt % to 30 wt % Tulsi herb, relative to the total weight of curcumin, ginger, ashwagandha and Tulsi herb, and methods of making and using the compositions, are provided.

Claims

1. A composition comprising: 1 wt-% to 10 wt-% curcumin or turmeric; 50 wt-% to 60 wt-% ginger; 10 wt-% to 20 wt-% ashwagandha; and 25 wt % to 30 wt % Tulsi herb, relative to the total weight of curcumin, ginger, ashwagandha and Tulsi herb.

2. The composition of claim 1 comprising 2 wt-% to 8 wt-% turmeric or curcumin; 50 wt-% to 60 wt-% ginger; 12 wt-% to 18 wt-% ashwagandha; and 25 wt % to 30 wt % Tulsi herb, relative to the total weight of the turmeric, ginger, ashwagandha and Tulsi herb.

3. The composition of claim 1 which is a powder or solid.

4. The composition of claim 1 which is an aqueous liquid.

5. The composition of claim 1 which further comprises one or more of vitamin C, vitamin D, vitamin B12, biotin, magnesium, iron, flax seed, L glutamine, or garlic.

6. The composition of claim 1 which does not include calcium, vitamin E, zinc or selenium.

7. The composition of claim 1 which does not include an anti-oxidant.

8. The composition of claim 1 wherein the curcumin or turmeric is about 50 mg to about 500 mg or about 25 mg to about 250 mg.

9. The composition of claim 1 wherein the curcumin or turmeric is about 10 mg to 150 mg or about 100 mg to about 200 mg.

10. The composition of claim 1 wherein the ashwagandha is about 200 mg to about 1000 mg.

11. The composition of claim 1 wherein the ashwagandha is about 75 mg to about 250 mg or about 300 mg to about 500 mg.

12. The composition of claim 1 wherein the tulsi herb is about 0.12 gm to about 0.5 gm.

13. The composition of claim 1 wherein the tulsi herb is about 0.5 gm to about 1 gm or about 1 gm to about 2 gm.

14. The composition of claim 1 wherein the ginger is about 1 gm to about 2 gm or about 2 gm to about 5 gm.

15. The composition of claim 1 wherein the ginger is about 0.25 gm to about 1 gm.

16. The composition of claim 3 which further comprises a source of protein, and optionally one or more fruits, one or more vegetables, one or more sweeteners and/or one or more flavorings.

17. The composition of claim 4 which further comprises one or more fruits and optionally one or more sweeteners and/or one or more flavorings.

18. A method comprising administering to a human the composition of claim 1.

19. The method of claim 18 wherein the ratio of tulsi herb to ginger in the composition is about 1:1, 1:2, 1:3 or 1:4; the ratio of curcumin to ashwagandha in the composition is about 1:1.5, 1:2.5, 1:1, or 1:6; or the ratio of ashwagandha to ginger in the composition is about 1:3, 1:5, 1:12 or 1:20.

20. The method of claim 19 wherein the composition comprises about 0.5 g to about 1 g of ginger, about 150 mg to about 250 mg ashwagandha, about 0.25 g to about 0.5 g tulsi herb, and about 25 mg to about 150 mg turmeric or curcumin; or wherein the composition comprises about 0.3 g to about 0.7 g of ginger, about 100 mg to about 170 mg ashwagandha, about 0.15 g to about 0.35 g tulsi herb, and about 15 mg to about 100 mg turmeric or curcumin; or wherein the composition comprises about 0.25 g to about 0.5 g of ginger, about 75 mg to about 125 mg ashwagandha, about 0.12 g to about 0.25 g tulsi herb, and about 12 mg to about 75 mg turmeric or curcumin or wherein the composition comprises about 0.05 g to about 5 g of ginger, about 100 mg to about 2 g ashwagandha, about 0.25 g to about 2 g tulsi herb, and about 25 mg to about 2 g turmeric or curcumin.

Description

DETAILED DESCRIPTION

[0014] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as is commonly understood by one of skill in the art to which the claimed subject matter belongs.

[0015] It is to be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of any subject matter claimed. In this application, the use of the singular includes the plural unless specifically stated otherwise.

[0016] In the present description, any concentration range, percentage range, ratio range, or integer range is to be understood to include the value of any integer within the recited range and, when appropriate, fractions thereof (such as one tenth and one hundredth of an integer), unless otherwise indicated.

[0017] As used herein, “about” means ±5% of the indicated range, value, sequence, or structure, unless otherwise indicated.

[0018] It should be understood that the terms “a” and “an” as used herein refer to “one or more” of the enumerated components unless otherwise indicated or dictated by its context. The use of the alternative (e.g., “or”) should be understood to mean either one, both, or any combination thereof of the alternatives. As used herein, the terms “include” and “comprise” are used synonymously.

[0019] As used herein, the term “formulation” or the term “formulations” may include a plurality of ingredients including two or more of ashwagandha, turmeric, holy basil and ginger. Such formulations may include other ingredients such as carriers, excipients, solvents, flavors, or any other ingredients as further described herein. For common excipients and carriers, see Remington's Pharmaceutical Sciences, infra, listing various excipients, diluents, additives, carriers, lubricants, and the like.

[0020] As used herein, the term “animal” includes any living organism characterized by voluntary movement.

[0021] As used herein, the term “subject” may include a mammal such as a human, unless specified otherwise.

[0022] As used herein, the term “%” or “wt. %” is a percent by weight value based on a total weight (taken as 100 wt. %) of the formulation with a specific set of ingredients or all of its constituent ingredients accounted for, such as listed ingredients (active and/or inactive), excipients (if any), carriers (if any), or other active ingredients (if any), unless indicated otherwise.

[0023] As used herein, the term “organic” may include ingredients that may be farmed or grown without the use of certain pesticides, antibiotics and/or genetically altered or genetically modified plants, seeds, or organisms.

[0024] As used herein, the term “non-organic” may include ingredients that may be farmed or grown, optionally with the use of pesticides, antibiotics and/or genetically altered or genetically modified plants, seeds, or organisms.

[0025] As used herein, the term “treatment” may include care provided to improve a condition or alleviate some discomfort or undesirable consequence of the condition such as a chronic disease or condition, or even an acute disease or condition or illness, etc.

[0026] As used herein, the term “symptomatic relief” may include control or alleviation of symptoms and/or side effects obtained with the aid or ingestion of one or more embodiments of the disclosed compositions.

[0027] According to one or more illustrative embodiments, formulation(s) in connection with the present disclosure may include one or more of the numerous constituents described herein.

[0028] Any one or more of the formulation(s) or embodiment(s) thereof described herein may have varying ingredient contents. Thus, for example, the amount of each ingredient may fluctuate within a certain range (but not limited to): about ±1%, up to about ±10%, as disclosed herein. The various embodiments may also include well-known excipients, carriers, fillers, pigments, colorants, preservatives, diluents, solvents, and emulsifiers suitable for use in formulations. Such embodiments may optionally include active ingredients in various forms, including, but not limited to, liquids, powders, syrups, shakes, tablets, capsules, e.g., gelatin capsules, concentrates, pills, emulsions, and the like.

[0029] Embodiments may provide dietary supplementation, nutritional supplementation, promote synergistic absorption of certain constituents, promote enhanced activity of certain constituents, promote or provide superior symptomatic relief, treatment or some other health benefit from the combination of the constituent ingredients as opposed to that of the constituent ingredients being administered separately.

[0030] In the one or more embodiments, any combination of herbs and/or natural products may be provided in a powder, e.g., a mixture of those products or as individual products, may be added to a base powder, or base liquid, e.g., soy milk, and resuspended therein, thereby providing a mixture where the combination of herbs and/or natural products is dissolved or suspended in the base liquid which may provide a pleasant taste, composition solubility, composition stability, and/or additional nutritional benefits. In addition to ashwagandha, turmeric, holy basil and ginger, the composition may include spice ingredients including, not limited to, cumin (Cuminum cyminum), black pepper (Piper nigrum), cinnamon (Cinnamonum zevlanicum), coriander (Coriandrum sativum), red pepper (Capsicum frutescens), clove (Syzygium aromaticum), ginger (Zingiber officinale), tejpat (Cinnamon tamala), fennel (Foeniculum vulgare), Kaala Jeera (black cumin), cardamom (Amomum subulatum), kalonji (Nigella sativa), ajowan (Trachyspermum ammi), mint (Mentha piperta), sesame seeds (Sesamum indicum), asafetida (Ferula narthex), curry leaves (Murraya koenigil), pomegranate (Punica granatum), nutmeg (Myristica fragrans), saffron (Coccus sativus), dill (Anethum graveolens), oregano (Origanum vulgare), coriander (Coriandrum sativum), parsley (Petroselinum crispum), camphor (Cinnamomum camphor), licorice (Glycyrrhiza glabra), caraway (Carum carvl), mustard (Brassica juncea), tamarind (Tamarindus indica), rosemary (Rosmarinus officinalis), onion (Allium fistulosum), garlic (Allium sativum), almonds (Amygdalus comunis), cashews (Anacardium occidentale), walnut (Juglans nigra), mace (Myristica fragrans), mango (Magnifera indica), prunes (Prunus domestica), raisins (Vitis vinifera), pecans (Carya illinoensis), figs (Ficus carica), fenugreek (Trigonella foneum-gracium), fenugreek seeds, flax (Linum usitatissimum), til (Sesamum indicum), and lemon grass (Cymbogogon filexusosus). Other plant materials (e.g., ginseng), teas (e.g., tea, green tea, herbal teas, etc.), purified natural ingredients of plant materials or synthetic equivalents (e.g., vanilla), inorganic salts, and sweeteners individually or in any combination may also be added to the formulations. Sweeteners can include either artificial sweeteners (e.g., cyclamate, saccharine, aspartame, acesulfame potassium, sucralose, sugar alcohols) or natural product sweeteners (stevioside, Stevia, sucrose, xylitol, Luohan, glucose, maltose, honey, can sugar or maple syrup etc.) may be added. Cocoa and chocolate powders may be one of the additives. Lipids (e.g., lecithin, soy lecithin) may be added (e.g., as emulsifiers), carbohydrates (e.g., sugars, starches, etc.), grains, and malts (e.g., barley malt) may also be used as ingredients. Proteins may be added or the proteins from high protein content ingredients such as peanuts or soy may be used to provide a protein content of at least about 40% by weight, or more, based on a total weight of a particular embodiment.

[0031] In one embodiment of a powder form compositions, an ashwagandha powder may range from about 10% to about 20% of the total weight of the ashwagandha, holy basil, turmeric and ginger, a turmeric powder may be in range from about 2% to about 8% based on the total weight of the composition, a tulsi powder may be in a range from about 23% to about 29% of the total weight of the ashwagandha, holy basil, turmeric and ginger, and a ginger powder may be in a range from about 52% to about 58% of the total weight of the ashwagandha, holy basil, turmeric and ginger.

[0032] In one embodiment, the ashwagandha may range from about 12% to about 18% of the total weight of the ashwagandha, holy basil, turmeric and ginger, the turmeric may be in range from about 2.5% to about 8% based on the total weight of the composition, the tulsi may be in a range from about 25% to about 29% of the total weight of the ashwagandha, holy basil, turmeric and ginger, and the ginger may be in a range from about 52% to about 56% of the total weight of the ashwagandha, holy basil, turmeric and ginger.

[0033] The powder compositions can be formulated in any suitable product form. Such product forms include but are not limited to a solid or a solution, e.g., a liquid, a dispersion, an emulsion, or a powder. The present compositions may include a carrier. A useful carrier is one that is acceptable for ingestion. Useful carriers may include, but are not limited to, one or more aqueous systems, oils such as vegetable or mineral oils, water, fruit juices, cultured dairy products, (e.g., yogurt), dairy products (e.g., milk), carbonated or non-carbonated beverages, and mixtures of the aforesaid. The powder compositions may be conveniently incorporated into a variety of liquids or solid compositions including, but not limited to, powders and other solids, liquid beverages (teas, mineral water, milk and other dairy products), capsules, tablets, food such as nutrient bars, cookies or other bakery items, etc.

[0034] The nutraceutical compositions may be administered in combination with a nutraceutically acceptable carrier. The active ingredients in such formulations may comprise from 1% by weight to 99% by weight, or alternatively, 0.1% by weight to 99.9% by weight. “Nutraceutically acceptable carrier” means any carrier, which may be a diluent or excipient that is compatible with the other ingredients of the formulation and not deleterious to the user. Thus, the compositions may be administered in combination with a nutraceutically acceptable carrier. The active ingredients in such formulations may comprise from 1% by weight to 99% by weight, or alternatively, 0.1% by weight to 99.9% by weight.

[0035] In one embodiment, the composition is optionally provided in liquid form, dehydrated form, powder form, or dehydrated powder form.

[0036] In one embodiment, the composition comprises curcumin in an amount of about 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg, 45 mg, 50 mg, 55 mg, 60 mg, 65 mg, 70 mg, 75 mg, 80 mg, 85 mg, 90 mg, 95 mg, 100 mg, 105 mg, 110 mg, 115 mg, 120 mg, 125 mg, 130 mg, 135 mg, 140 mg, 145 mg, 150 mg, 160 mg, 170 mg, 180 mg, 190 mg, 200 mg, 210 mg, 220 mg, 230 mg, 240 mg, 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1000 mg, 1100 mg, 1200 mg, 1200 mg, 1300 mg, 1400 mg, 1500 mg and being within about at least one of or just one off 1%, ±2%, ±3%, ±4%, ±5%, 16%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, 22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0037] In one embodiment, the composition comprises curcumin in an amount of about 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg, 45 mg, 50 mg, 55 mg, 60 mg, 65 mg, 70 mg, 75 mg, 80 mg, 85 mg, 90 mg, 95 mg, 100 mg, 105 mg, 110 mg, 115 mg, 120 mg, 125 mg, 130 mg, 135 mg, 140 mg, 145 mg, 150 mg, 160 mg, 170 mg, 180 mg, 190 mg, 200 mg, 210 mg, 220 mg, 230 mg, 240 mg, 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, or 500 mg and being within about at least one of or just one of ±1%, ±2%, ±3%, ±4%, ±5%, ±6%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, 22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0038] In one embodiment, the composition comprises ginger root in an amount of about 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg, 45 mg, 50 mg, 55 mg, 60 mg, 65 mg, 70 mg, 75 mg, 80 mg, 85 mg, 90 mg, 95 mg, 100 mg, 105 mg, 110 mg, 115 mg, 120 mg, 125 mg, 130 mg, 135 mg, 140 mg, 145 mg, 150 mg, 160 mg, 170 mg, 180 mg, 190 mg, 200 mg, 210 mg, 220 mg, 230 mg, 240 mg, 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1000 mg, 1100 mg, 1200 mg, 1200 mg, 1300 mg, 1400 mg, 1500 mg, 1600 mg, 1700 mg, 1800 mg, 1900 mg, 2000 mg, 2500 mg, 3000 mg, 3500 mg, 4000 mg, 4500 mg, or 5000 mg and being within about at least one of or just one of ±1%, ±2%, ±3%, ±4%, ±5%, ±6%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, ±22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0039] In one embodiment, the composition comprises ginger root in an amount of about 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1000 mg, 1100 mg, 1200 mg, 1200 mg, 1300 mg, 1400 mg, 1500 mg, 1600 mg, 1700 mg, 1800 mg, 1900 mg, 2000 mg or 2500 mg and being within about at least one of or just one of ±1%, ±2%, ±3%, ±4%, ±5%, ±6%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, ±22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0040] In one embodiment, the composition comprises holy basil in an amount of about 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg, 45 mg, 50 mg, 55 mg, 60 mg, 65 mg, 70 mg, 75 mg, 80 mg, 85 mg, 90 mg, 95 mg, 100 mg, 105 mg, 110 mg, 115 mg, 120 mg, 125 mg, 130 mg, 135 mg, 140 mg, 145 mg, 150 mg, 160 mg, 170 mg, 180 mg, 190 mg, 200 mg, 210 mg, 220 mg, 230 mg, 240 mg, 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1000 mg, 1100 mg, 1200 mg, 1200 mg, 1300 mg, 1400 mg, or 1500 mg, and being within about at least one of or just one of ±1%, ±2%, ±3%, ±4%, ±5%, ±6%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, ±22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0041] In one embodiment, the composition comprises holy basil in an amount of about 100 mg, 105 mg, 110 mg, 115 mg, 120 mg, 125 mg, 130 mg, 135 mg, 140 mg, 145 mg, 150 mg, 160 mg, 170 mg, 180 mg, 190 mg, 200 mg, 210 mg, 220 mg, 230 mg, 240 mg, 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1000 mg, 1100 mg, 1200 mg, 1200 mg, 1300 mg, 1400 mg, or 1500 mg, and being within about at least one of or just one of ±1%, ±2%, ±3%, ±4%, ±5%, ±6%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, ±22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0042] In one embodiment, the composition comprises ashwagandha in an amount of about 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg, 45 mg, 50 mg, 55 mg, 60 mg, 65 mg, 70 mg, 75 mg, 80 mg, 85 mg, 90 mg, 95 mg, 100 mg, 105 mg, 110 mg, 115 mg, 120 mg, 125 mg, 130 mg, 135 mg, 140 mg, 145 mg, 150 mg, 160 mg, 170 mg, 180 mg, 190 mg, 200 mg, 210 mg, 220 mg, 230 mg, 240 mg, 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 700 mg, 800 mg, 900 mg, or 1000 mg and being within about at least one of or just one of ±1%, ±2%, ±3%, ±4%, ±5%, ±6%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, ±22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0043] In one embodiment, the composition comprises ashwagandha in an amount of about 100 mg, 105 mg, 110 mg, 115 mg, 120 mg, 125 mg, 130 mg, 135 mg, 140 mg, 145 mg, 150 mg, 160 mg, 170 mg, 180 mg, 190 mg, 200 mg, 210 mg, 220 mg, 230 mg, 240 mg, 250 mg, 260 mg, 270 mg, 280 mg, 290 mg, 300 mg, 310 mg, 320 mg, 330 mg, 340 mg, 350 mg, 360 mg, 370 mg, 380 mg, 390 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 700 mg, 800 mg, 900 mg, or 1000 mg and being within about at least one of or just one of ±1%, ±2%, ±3%, ±4%, ±5%, ±6%, ±7%, ±8%, ±9%, ±10%, ±11%, ±12%, ±13%, ±14%, ±15%, ±16%, ±17%, ±18%, ±19%, ±20%, ±21%, ±22%, ±23%, 24%, and ±25% for each of the mg values, respectively.

[0044] In one embodiment, the amounts are per serving.

[0045] In one embodiment, the amounts are daily values.

[0046] In one embodiment, the present disclosure provides dietary supplements.

[0047] Provided herein are methods and formulations of dietary supplements that when administered to an individual treat, support and/or enhance, for example, repair properties or immune function, or provide an anti-inflammatory effect or optionally provide an anti-oxidant effect or decrease fatigue or nausea, or any combination thereof.

Exemplary Additional Components

[0048] The methods, dietary supplements and formulations described herein may comprise at least one of the ingredients (components) discussed below. In certain embodiments, formulations described herein comprise a plurality of ingredients described below. In certain embodiments, two or more ingredients may be combined in an amount suitable to provide synergistic effects. Formulations and dietary supplements described herein may contain other active and inactive ingredients in addition to two or more ingredients described herein.

[0049] Thus, the compositions may include other compounds or compositions, such as mixtures, including but not limited to one or more of iron, useful to overcome fatigue and stimulate bone marrow, vitamin B12, useful to overcome fatigue, vitamin D, useful to increase bone development, flax seed, which has anti-inflammatory, biotin, magnesium, immune boosters such as garlic, L-glutamine, polyphenols such as green tea and vitamin C. In one embodiment, the compositions may not include calcium and/or anti-oxidants like vitamin E, selenium or zinc.

[0050] The additional ingredients or the carrier may provide for a caloric supplement.

[0051] In one embodiment, the composition may include biotin (alternatively called vitamin H or coenzyme R a water-soluble B-vitamin (vitamin B.sub.7)). Certain methods and formulations described herein comprise a suitable amount of biotin or derivative or analog thereof. In certain embodiments, methods and formulations of dietary supplements comprise biotin or derivative or analog thereof in an amount suitable to support and/or enhance at least one of: blood sugar control, cholesterol levels, insulin response to glucose load, manufacture and utilization of carbohydrates/fats/amino acids, maintenance of insulin receptor site sensitivity, glucokinase activity, hair growth, nail health and metabolism.

[0052] In one embodiment, the composition may include vitamin C or L-ascorbic acid, or ascorbate: Certain methods and formulations described herein comprise a suitable amount of vitamin C or derivative or analog thereof. In certain embodiments, methods and formulations of dietary supplements comprise vitamin C or derivative or analog thereof in an amount suitable to support and/or enhance at least one of: neutralization of toxins, glutathione levels, immune system, removal of heavy metal toxins, blood sugar metabolism, beta cells of the pancreas, antioxidation, and growth and repair of tissues. In some embodiments, the concentration of vitamin C in the formulation is from about 1% to about 8% by weight. In some embodiments is a formulation described herein, the concentration of vitamin C in the formulation is from about 2% to about 9% by weight.

[0053] In one embodiment, the composition may include vitamin D. In some embodiments, the source of Vitamin D is vitamin D3 (also known as cholecalciferol). In some embodiments, the source of Vitamin D is vitamin D2 (ergocalciferol). Certain methods and formulations described herein comprise a suitable amount of vitamin D or derivative or analog thereof. In certain embodiments, methods and formulations of dietary supplements comprise vitamin D or derivative or analog thereof in an amount suitable to support and/or enhance at least one of: blood sugar metabolism, heart and cardiovascular health, immune function, insulin receptor site activity, bone health, reducing the risk of some forms of cancer, alleviating musculoskeletal pain.

[0054] In one embodiment, the composition may include vitamin B12 also called cobalamin. In some embodiments the source of vitamin B12 is methylcobalamin. In some embodiments, the source of Vitamin B12 is cyanocobalamin. Certain methods and formulations described herein comprise a suitable amount of vitamin B12 or derivative or analog thereof. In certain embodiments, methods and formulations of dietary supplements comprise vitamin B12 or derivative or analog thereof in an amount suitable to support and/or enhance at least one of: healthy homocysteine levels, healthy red blood cells, energy production, immune system and neuro-protection. In some instances, the concentration of vitamin B12 is from about 0.5% to about 10%, about 1% to about 10%, about 1% to about 8%, about 2% to about 7%, or about 3% to about 6% by weight.

[0055] In one embodiment, the composition may include L-glutamine. Certain methods and formulations described herein comprise a suitable amount of L-glutamine or derivative or analog thereof. In certain embodiments, methods and formulations of dietary supplements comprise L-glutamine or derivative or analog thereof in an amount suitable to support and/or enhance at least one of: sulfation, methylation, detoxification, glutathione storage, oxidative stress management and small intestine health. In some embodiments, the concentration of glutamine in the formulation is from about 0.5% to about 6% by weight. In some cases, the concentration of glutamine is from about 0.5% to about 6%, about 0.8% to about 5%, about 1% to about 4%, or about 1.2% to about 3% by weight.

Exemplary Formulations

[0056] Provided herein are exemplary formulations.

[0057] In some embodiments, the concentration of ginger in a liquid formulation is from about 1% to about 10% by total weight. In some cases, the concentration of ginger is from about 0.5°/o to about 15%, about 1% to about 10%, about 2% to about 8%, or about 3% to about 6% by total weight.

[0058] In some embodiments, the concentration of turmeric extract in a liquid formulation is from about 0.1% to about 1% by total weight. In some instances, the concentration of curcumin is from about 0.5% to about 10%, about 1% to about 8%, about 2% to about 7%, or about 3% to about 6% by total weight.

[0059] In some embodiments, concentration of ashwagandha root extract in a liquid formulation is from about 0.3% to about 0.6% by total weight.

[0060] In some embodiments, the concentration of holy basil leaf extract in a liquid formulation is from about 0.5% to about 5% by total weight. —In some instances, the concentration of ashwagandha root extract is from about 1% to about 30%, about 2% to about 20%, about 4% to about 16%, or about 6% to about 12% by total weight.

[0061] In some instances, the concentration of holy basil leaf extract is from about 1% to about 15%, about 3% to about 13%, or about 4% to about 10% by total weight.

[0062] In some embodiments, one or more formulations described herein may be used as a dietary supplement and/or anticancer agent. The formulations may comprise either the above listed ingredients, its active compounds, or said ingredients and active compounds plus one or more nutraceutically acceptable carriers. In addition to the ingredients discussed above, methods of determining active ingredients and screening for activity in the formulations described herein can be carried out according to methods known to those of skill in the art, and according to methods described in the examples herein. Formulations described herein may be mixed with nutraceutically acceptable carriers known to those of skill in the art, and administered according to methods known to those of skill in the art including: oral administration in the form of juice or milk or other beverage, powders, tablets, suspension, emulsifiers, capsules, granules, suspensions, spirits, or syrups.

[0063] In addition, well-known excipients in the form of solid or liquid maybe used. The several examples of excipients used to administer the dosage forms may include for powders for oral administration: lactose, crystalline cellulose, starch, dextrin, calcium phosphate, calcium carbonate, synthetic and natural aluminum dioxide, magnesium oxide, dried aluminum hydroxide, magnesium stearate, and/or sodium bicarbonate; Excipients in liquids may include water, glycerin, propylene glycol, sweet-taste syrup, ethanol, fatty oil, ethylene glycol, polyethylene glycol, or sorbitol.

[0064] Formulations discussed herein can be administered in any of the forms considered herein, or otherwise known to those of skill in the art. In some embodiments, the formulation is administered orally in a liquid form, either as an extract, concentrated extract or other liquid form. In some embodiments, the formulation is administered orally once a day, twice a day, three times a day, or four times a day, with each dosing varying between, for example, from about 2 oz to about 40 oz, for instance, about 5 oz to about 20 oz such as 8 oz, 10 oz, 16 oz or 24 oz.

[0065] A formulation described herein may be administered as a dietary supplement to facilitate normal physiological function and growth.

[0066] Provided in Tables A-D are exemplary formulations:

TABLE-US-00001 TABLE A Amount Per Daily Serving Amount Vitamin C 2.5-250 mg 10-500 mg Vitamin D 250-1.500 IU 1,000-3,000 IU Holy basil 0.1 g-0.5 g  0.5 g-1 g   Vitamin B12 25-250 mcg 100-1000 mcg Biotin 6-125 mcg 25-250 mcg Ashwagandha 75 mg-250 mg 300 mg-500 mg Curcumin 25 mg-150 mg  50 mg-300 mg (tetrahydroxycurcumin) L-Glutamine 0.5-3 grams 2.5-10 grams Ginger root 0.25 g-1 g    1 g-2 g

TABLE-US-00002 TABLE B Amount Per Daily Serving Value Vitamin C 100-500 mg Vitamin B12 100-1000 mcg Biotin 25-250 mcg Magnesium 25-250 mg Ashwagandha Root Extract 70 mg-300 mg 250 mg-600 mg Holy Basil Leaf Extract 0.05 g-1 g    0.25 g-2 g   Curcumin 12 mg-150 mg  50 mg-300 mg Ginger Root Extract 0.1 g-2 g   0.5 g-4 g   Iron 1-12 mg 4-25 mg Flax seed 2.5-25 grams 10-50 grams Garlic 125-2500 mg 500-5000 mg L-Glutamine 0.5-5 grams 2.5-10 grams

TABLE-US-00003 TABLE C Amount Per Daily Serving Value Vitamin C 100-500 mg Ashwagandha 250 mg 500 mg Ginger 1 g 2 g Vitamin B12 100-1000 mcg Biotin 25-250 mcg Curcumin 50 mg 100 mg Magnesium 6-125 mg 25-250 mg Holy basil 0.5 g 1 g

TABLE-US-00004 TABLE D Amount Per 8 oz Daily Serving Value Ashwagandha 100 mg to 500 mg Up to 2 g Ginger 0.05 g to 0.5 g  Up to 5 g Curcumin  25 mg to 250 mg Up to 2 g Holy basil 250 mg to 500 mg Up to 2 g

[0067] The physical form of the unit may be solid, liquid or a semi solid. In the solid form, the unit is a chewable lozenge tablet, a sugar coated oral tablet, a polymer film coated tablet, a hard gelatin encapsulated tablet, a soft gelatin encapsulated tablet. In the solid form, the unit can also be a sachet, a bubble bag or an herbal dip bag containing predetermined amounts the plant ingredients. When the unit is sachet or bag type, the constituents of the unit is mixed with hot water and consumed as a health drink. When the unit is an herbal dip bag type, the herbal dip bag is dipped into hot water and consumed as a polyherbal infusion.

[0068] In the solid form, the plant ingredients may be combined with excipients such suitable edible carriers, binders, diluents, disintegrating agents, coloring agents, fillers, stabilizers, emulsifiers, film-forming agents, plasticizers, wetting agents, thickeners, lubricants and sweetening agents.

[0069] In the liquid form, the unit is a polyherbal syrup or a polyherbal smoothie health drink.

[0070] In the liquid form, the plant ingredients are combined with suitable liquid carrier, a coloring agent, a flavoring agent, a preservative and a sweetening agent. The liquid carrier is selected from water, fatty oil, glycol, oil, alcohol and combinations thereof.

[0071] In the semi-solid form, the unit of the polyherbal composition is in the form of a jelly.

[0072] In one embodiment of the disclosure, the polyherbal composition comprises powdered plant parts of different herbs.

[0073] The invention will be further described by the following non-limiting examples.

Example 1

[0074] In one embodiment, the composition may have about 50 wt % to about 60 wt %, e.g., about 55 wt %, whole ginger extract relative to the total wt % of ginger, ashwagandha, holy basil and turmeric or curcumin.

[0075] In one embodiment, the composition may have about 5 wt % to about 20 wt %, e.g., about 10 wt % to about 18 wt %, ashwagandha relative to the total wt % of ginger, ashwagandha, holy basil and turmeric or curcumin.

[0076] In one embodiment, the composition may have about 25 wt % top about 30 wt %, e.g., about 27 wt %, of tulsi herb relative to the total wt % of ginger, ashwagandha, holy basil and turmeric or curcumin.

[0077] In one embodiment, the composition may have about 1 wt % to about 8 wt %, about 2.5 to about 8 wt %, of curcumin relative to the total wt % of ginger, ashwagandha, holy basil and turmeric or curcumin.

Example 2

[0078] In one embodiment, the ratio of basil to ginger extract in a composition is about 0.5:2, 1:1 or 1:2.

[0079] In one embodiment, the ratio of ashwagandha to ginger extract in a composition is about 1:2, 1:3, 1:4 or 1:6.

[0080] In one embodiment, the ratio of curcumin or turmeric to ashwagandha in a composition is 1:6, 1:10, 1:1, 1.3:1, 1:1.25, or 1:1.5.

Example 3

[0081] In one embodiment, the composition may have about 0.5 gm to about 1 gm, about 0.3 gm to about 7 gm or about 0.25 to about 0.5 gm per serving of Syussai whole ginger extract.

[0082] In one embodiment, the composition may have about 150 mg to about 250 mg, about 100 to about 170 mg or about 75-about 125 mg per serving of ashwagandha.

[0083] In one embodiment, the composition may have about 0.25 mg to about 0.5 mg, about 0.15 to about 0.35 mg, or about 0.125 to about 0.25 mg per serving of tulsi herb.

[0084] In one embodiment, the composition may have about 12 mg to about 75 mg, about 15 mg to about 100 mg, or about 25 mg to about 150 mg per serving of turmeric or curcumin.

Example 4

[0085]

TABLE-US-00005 Exemplary Exemplary Daily Value Individual Dose Formula A Formula B Formula C Formula D Formula E Ginger 1-2 g 0.25 g-1 g 0.25 g 0.5 g 0.75 g 1 g 0.5 Ashwagandha 300-500 mg 75-250 mg 100 mg 200 mg 250 mg 75 mg 100 mg Tulsi 0.5-1 g 0.1-0.5 g 0.5 g 0.4 g 0.3 g 0.2 g 0.1 g Curcumin 50-300 mg 6-50 μg 50 μg 6 μg 45 μg 15 μg 25 μg Flax seed 25-35 gm 25-35 grams 25-35 grams 25-35 grams Iron 4-25 mg 4 mg 15 mg 25 mg Vitamin B12 100-1000 mcg 1000 mcg 500 mcg 100 mcg Biotin 25-250 mcg 25 mcg 150 mcg 250 mcg Vitamin D 1000-3000 IU 3000 IU 2000 IU 1000 IU Vitamin C 100-500 mg 100 mg 250 mg 500 mg

Example 5

[0086] Individual doses or daily values may be provided in a single container, e.g., one where a powder concentrate is added to a carrier such as tea, e.g., green tea, milk, e.g., soy milk, cow's milk, almond milk, oat milk, so as to suspend or dissolve the powder. For example, curcumin or turmeric at 25 to 100 mg per dose or 100 to 200 mg/day is dissolved or suspended in a liquid and portions thereof may be consumed throughout the day. Syussai whole Ginger extract at 2 gms per day or 100 mg/kg dissolved or suspended in a liquid and portions thereof may be consumed throughout the day. Ashwagandha at 300-500 mg/day is dissolved or suspended in a liquid and portions thereof may be consumed throughout the day. Tulsi herb at 500 mg-1 gm/day is dissolved or suspended in a liquid and portions thereof may be consumed throughout the day. Ground Flax seed at 25-35 gm/day is dissolved or suspended in a liquid and portions thereof may be consumed throughout the day.

Example 6

[0087] In one embodiment, individual doses or daily values, e.g., in a tablet, for ashwagandha, ginger, holy basil and/or turmeric or curcumin as disclosed herein may be combined with one, two, three, four five, ten, fifteen, twenty or more of the following: calcium carbonate, potassium chloride, dibasic calcium phosphate, magnesium oxide, microcrystalline cellulose, ascorbic acid (Vit. C), L-alpha tocopheryl acetate (Vit. E), maltodextrin, modified corn starch, corn starch, beta-carotene, BHT (to preserve freshness), biotin, calcium pantothenate, cholecalciferol (Vit. D.sub.3), chromium picolinate, copper sulfate, crospovidone, cyanocobalamin (Vit. B.sub.12), folic acid, gelatin, hypromellose, lutein, lycopene, magnesium stearate, manganese sulfate, medium-chain triglycerides, niacinamide, phytonadione (vit. K), dextrose, potassium iodide, pyridoxine hydrochloride (vit. B.sub.6), riboflavin (vit. B.sub.2), silicon dioxide, sodium ascorbate, sodium molybdate, sodium selenate, thiamine mononitrate (vit. B.sub.1), titanium dioxide, tocopherols, vitamin A, or zinc oxide.

[0088] Individual doses or daily values, e.g., in a tablet, for ashwagandha, ginger, holy basil and/or turmeric or curcumin as disclosed herein may be combined with one, two, three, four five, ten, fifteen, twenty or more of the following: calcium carbonate, potassium chloride, dibasic calcium phosphate, magnesium oxide, microcrystalline cellulose, ascorbic acid (Vit. C), L-alpha tocopheryl acetate (Vit. E), maltodextrin, beta-carotene, biotin, calcium pantothenate, cholecalciferol (Vit. D.sub.3), chromium picolinate, copper sulfate, crospovidone, cyanocobalamin (Vit. B.sub.12), folic acid, gelatin, hypromellose, lutein, lycopene, magnesium stearate, manganese sulfate, medium-chain triglycerides, niacinamide, phytonadione (vit. K), potassium iodide, pyridoxine hydrochloride (vit. B.sub.6), riboflavin (vit. B.sub.2), sodium ascorbate, sodium molybdate, thiamine mononitrate (vit. B.sub.1), or vitamin A.

[0089] Individual doses or daily values, e.g., in a tablet, for ashwagandha, ginger, holy basil and/or turmeric or curcumin as disclosed herein may be combined with one, two, three, four five, ten, fifteen, twenty or more of the following: calcium carbonate, potassium chloride, dibasic calcium phosphate, magnesium oxide, microcrystalline cellulose, ascorbic acid (Vit. C), L-alpha tocopheryl acetate (Vit. E), maltodextrin, modified corn starch, corn starch, beta-carotene, BHT (to preserve freshness), biotin, calcium pantothenate, cholecalciferol (Vit. D.sub.3), chromium picolinate, copper sulfate, crospovidone, cyanocobalamin (Vit. B.sub.12), folic acid, gelatin, hypromellose, lutein, lycopene, magnesium stearate, manganese sulfate, medium-chain triglycerides, niacinamide, phytonadione (vit. K), polydextrose, potassium iodide, pyridoxine hydrochloride (vit. B.sub.6), red 40 lake, riboflavin (vit. B.sub.2), silicon dioxide, sodium ascorbate (to preserve freshness), sodium molybdate, sodium selenate, talc, thiamine mononitrate (vit. B.sub.1), titanium dioxide, tocopherols (to preserve freshness), vitamin A acetate, or zinc oxide.

For example, ranges are as follows:

TABLE-US-00006 Amount Per Serving Vitamin A 500-1000 mcg (40% as Beta-Carotene) Vitamin C 40-120 mg Vitamin D.sub.3 10-50 mcg Vitamin E 10-40 mg Vitamin K 10-150 mcg Thiamin 1-2 mg Riboflavin 1-3 mg Niacin 10-30 mg Vitamin B.sub.6 0.5-5 mg Folate 500-750 mcg DFE (400 mcg Folic Acid) Vitamin B.sub.12 1-50 mcg Biotin 10-50 mcg Pantothenic Acid 5-200 mg Calcium 220 mg Phosphorus 10-100 mg Iodine 100-200 mcg Magnesium 25-150 mg Zinc 5-15 mg Selenium 10-100 mcg Copper 0.1-10 mg Manganese 1-5 mg Chromium 10-150 mcg Molybdenum 10-100 mcg Chloride 50-500 mg Potassium 50-200 mg Lutein 100-500 mcg Lycopene 100-500 mcg
Specific amounts are as follows:

TABLE-US-00007 Amount Per Serving Vitamin A 750 mcg (40% as Beta-Carotene) Vitamin C 60 mg Vitamin D.sub.3 25 mcg (1,000 IU) Vitamin E 22.5 mg Vitamin K 30 mcg Thiamin 1.5 mg Riboflavin 1.7 mg Niacin 20 mg Vitamin B.sub.6 3 mg Folate 667 mcg DFE (400 mcg Folic Acid) Vitamin B.sub.12 25 mcg Biotin 30 mcg Pantothenic Acid 10 mg Calcium 220 mg Phosphorus 20 mg Iodine 150 mcg Magnesium 50 mg Zinc 11 mg Selenium 19 mcg Copper 0.5 mg Manganese 2.3 mg Chromium 50 mcg Molybdenum 45 mcg Chloride 72 mg Potassium 80 mg Lutein 250 mcg Lycopene 300 mcg

Example 7

[0090] In one example, individual doses or daily values, e.g., in a tablet, for ashwagandha, ginger, holy basil and/or turmeric or curcumin as disclosed herein may be combined with one, two three, four, five, ten, twenty or more of the following: calcium carbonate, magnesium oxide, potassium chloride, ascorbic acid, dibasic calcium phosphate, microcrystalline cellulose, maltodextrin, di-alpha tocopheryl acetate, modified corn starch, beta-carotene, BHT, biotin, calcium pantothenate, cholecaciciterol, chromium picolinate, copper sulfate, corn starch, crospovidone, cyanocobalamin, ferrous fumarate, folic acid, gelatin, hydrogenated palm oil, hypromelloses, lutein, magnesium stearate, manganese sulfate, medium-chain triglycerides, niacinamide, nickelous sulfate, phytonadione (Vit. K), polydextrose, potassium iodide, pyridoxine hydrochloride, riboflavin, silicon dioxide, sodium ascorbate, sodium metavanadate, sodium molybdate, sodium selenate, talc, thiamine mononitrite, titanium dioxide, tocopherols, or vitamin A acetate.

[0091] Individual doses or daily values, e.g., in a tablet, for ashwagandha, ginger, holy basil and/or turmeric or curcumin as disclosed herein may be combined with one, two, three, four five, ten, fifteen, twenty or more of the following: calcium carbonate, potassium chloride, dibasic calcium phosphate, magnesium oxide, microcrystalline cellulose, ascorbic acid, L-alpha tocopheryl acetate, maltodextrin, beta-carotene, biotin, calcium pantothenate, cholecalciferol, chromium picolinate, copper sulfate, crospovidone, cyanocobalamin, folic acid, gelatin, hypromellose, lutein, lycopene, magnesium stearate, manganese sulfate, medium-chain triglycerides, niacinamide, phytonadione, potassium iodide, pyridoxine hydrochloride, riboflavin, sodium ascorbate, sodium molybdate, thiamine mononitrate, or vitamin A

Exemplary ranges are as follows:

TABLE-US-00008 Amount Per Serving Vitamin A 2000-7000 IU (43% as Beta-Carotene) Vitamin C 25-200 mg Vitamin D 250-2,000 UI Vitamin E 10-50 IU Vitamin K 25-150 mcg Thiamin 0.5-3 mg Riboflavin 0.5-3 mg Niacin 5-25 mg Vitamin B.sub.6 1-10 mg Folic Acid 200-800 mcg Vitamin B.sub.12 1-100 mcg Biotin 10-500 mcg Pantothenic Acid 1-15 mg Calcium 200-2,000 mg Iron 1-20 mg Phosphorus 10-2000 mg Iodine 100-300 mcg Magnesium 50-500 mg Zinc 10-30 mg Selenium 10-50 mcg Copper 0.2-10 mg Manganese 1-3 mg Chromium 10-150 mcg Molybdenum 10-200 mcg Chloride 50-500 mg Potassium 50-1000 mg Nickel 1-10 mcg Silicon 1-10 mg Vanadium 5-20 mcg Lutein 150-500 mcg

TABLE-US-00009 Amount Per Serving Vitamin A 3,500 IU (43% as Beta-Carotene) Vitamin C 100 mg Vitamin D 1,000 UI Vitamin E 35 IU Vitamin K 50 mcg Thiamin 1.1 mg Riboflavin 1.1 mg Niacin 14 mg Vitamin B.sub.6 5 mg Folic Acid 400 mcg Vitamin B.sub.12 50 mcg Biotin 30 mcg Pantothenic Acid 5 mg Calcium 300 mg Iron 8 mg Phosphorus 20 mg Iodine 150 mcg Magnesium 100 mg Zinc 15 mg Selenium 22 mcg Copper 0.5 mg Manganese 2.3 mg Chromium 52 mcg Molybdenum 50 mcg Chloride 72 mg Potassium 80 mg Nickel 5 mcg Silicon 2 mg Vanadium 10 mcg Lutein 300 mcg

Example 8

[0092] Examples of specific 16 oz beverages (a “serving”) include but are not limited to:

Beverage A

[0093] 1.5 cup (12 oz) milk such as almond milk or soy milk. [0094] 1 cup of berries (fresh or frozen), such as strawberries or blueberries or raspberries [0095] 1 cup of bananas (fresh or frozen) [0096] 2 tablespoons of honey or another sweetener(s) in an amount that corresponds in sweetness to 2 tablespoons of honey [0097] ashwagandha, holy basil, turmeric and ginger in amounts disclosed herein, e.g., 2 capsules of each of ashwagandha, holy basil and turmeric, and 1 capsule of ginger, e.g., ginger at 0.05 gm to 0.5 gm per 8 oz or up to 5 g per day or 100 mg to 500 mg/kg; ashwagandha at 100 mg to 500 mg per 8 oz or up to 2 g/day; holy basil at 250 mg to 500 mg per 8 oz or up to 2 g/day; and curcumin at 25 mg to 250 mg per 8 oz or up to 2 g/day [0098] optionally 1 tablespoon of lemon

Beverage B

[0099] 12 oz of water including flavored water such as coconut water (no lemon) or tea (e.g., green tea) and optionally lemon, for example, 2 tablespoons of lemon [0100] 1 cup of berries (fresh or frozen) such as strawberries or blueberries or raspberries [0101] 1 cup of bananas (fresh or frozen) [0102] 2 tablespoons of honey or another sweetener(s) in an amount that corresponds in sweetness to 2 tablespoons of honey [0103] ashwagandha, holy basil, turmeric and ginger in amounts disclosed herein, e.g., 2 capsules of each of ashwagandha, holy basil and turmeric and 1 capsule of ginger, e.g., ginger at 0.05 gm to 0.5 gm per 8 oz or up to 5 g per day or 100 mg to 500 mg/kg; ashwagandha at 100 mg to 500 mg per 8 oz or up to 2 g/day; holy basil Vanadium 10 mcg Lutein 300 mcg at 250 mg to 500 mg per 8 oz or up to 2 g/day; and curcumin at 25 mg to 250 mg per 8 oz or up to 2 g/day [0104] optionally 1 tablespoon of lemon

Beverage C

[0105] 12 oz of green tea, e.g., decaffeinated green tea [0106] 1 cup of berries (fresh or frozen), e.g., raspberries or blueberries or strawberries [0107] 1 cup of bananas (fresh or frozen) [0108] 2 tablespoons of honey or another sweetener(s) in an amount that corresponds in sweetness to 2 tablespoons of honey [0109] ashwagandha, holy basil, turmeric and ginger in amounts disclosed herein, e.g., 2 capsules of each of ashwagandha, holy basil and turmeric, and 1 capsule of ginger, e.g., ginger at 0.05 gm to 0.5 gm per 8 oz or up to 5 g per day or 100 mg to 500 mg/kg; ashwagandha at 100 mg to 500 mg per 8 oz or up to 2 g/day; holy basil at 250 mg to 500 mg per 8 oz or up to 2 g/day; and curcumin at 25 mg to 250 mg per 8 oz or up to 2 g/day. [0110] optionally 2 tablespoons of lemon

[0111] All publications, patents and patent applications are incorporated herein by reference. While in the foregoing specification, this invention has been described in relation to certain preferred embodiments thereof, and many details have been set forth for purposes of illustration, it will be apparent to those skilled in the art that the invention is susceptible to additional embodiments and that certain of the details herein may be varied considerably without departing from the basic principles of the invention.