Anhydrous solid composition based on particles encapsulating a beneficial agent

Abstract

Provided is a solid anhydrous composition that comprises particles comprising a core containing at least one beneficial agent and an envelope surrounding the core. The envelope comprises at least one hydrophobically modified polysaccharide and at least one water-soluble carbohydrate and/or water-soluble polyol. The particles simultaneously have a poured powder density ranging from 300.0 g/l to 600.0 g/l and an absolute density of greater than 1.0. The envelope also comprises at least one structuring agent. Also provided is a cosmetic process for caring for and/or for the hygiene of and/or for conditioning and/or for fragrancing and/or for making up keratin material. The process comprises applying to the keratin material the above composition. Also provided is a cosmetic process for treating body odor and optionally human perspiration, which comprises applying to a keratin material a composition defined above comprising at least one deodorant and/or antiperspirant in free form and/or in encapsulated form.

Claims

1. A solid anhydrous composition comprising: 1) particles comprising a core containing at least one beneficial agent and an envelope surrounding the core; said envelope comprising at least one hydrophobically modified polysaccharide chosen from starch (C.sub.5-C.sub.20)alkenyl succinates and at least one water-soluble carbohydrate chosen from maltodextrins; said particles simultaneously having a poured powder density ranging from 300.0 g/l to 600.0 g/l and an absolute density of greater than 1.0, and wherein the particles are spherical and have a number-mean diameter ranging from 5 to 150 m; and 2) at least one structuring agent.

2. The composition as claimed in claim 1, comprising a physiologically acceptable medium.

3. The composition as claimed in claim 1, in which the particles have a number-mean diameter ranging from 5 to 10 m, and a volume-mean diameter ranging from 10 to 100 m.

4. The composition as claimed in claim 1, in which the hydrophobically modified polysaccharide is sodium starch octenyl succinate.

5. The composition as claimed in claim 1, in which the hydrophobically modified polysaccharide represents from 20% to 90% by weight, relative to the total weight of the envelope of the particle.

6. The composition as claimed in claim 1, in which the water-soluble carbohydrate is chosen from maltodextrins with a D.E. ranging from 12 to 20.

7. The composition as claimed in claim 1, in which the water-soluble carbohydrate(s) represent from 10% to 80% by weight relative to the total weight of the envelope of the particle.

8. The composition as claimed in claim 1, in which the envelope of the particles with release of beneficial agent is formed from at least one starch (C.sub.5-C.sub.20)alkenyl succinate and from at least one maltodextrin with a D.E. ranging from 4 to 20.

9. The composition as claimed in claim 8, in which the envelope of the particles with release of beneficial agent is formed from a) 20% to 90% by weight relative to the total weight of the envelope of the particle, and b) at least one maltodextrin with a D.E. ranging from 4 to 20 in an amount ranging from 10% to 80% by weight relative to the total weight of the envelope of the particle.

10. The composition as claimed in claim 1, in which the structuring agent is chosen from beeswax, lanolin wax, carnauba wax, candelilla wax, orange and lemon waxes, microcrystalline waxes, paraffins, ozokerite, polyethylene waxes, fatty acid triglycerides, stearyl alcohol, cetearyl alcohol, cetylstearyl alcohol, isomerized jojoba oil, hydrogenated sunflower oil, hydrogenated castor oil, hydrogenated coconut oil, hexyldecyl stearate, a mixture of soybean sterols and of oxyethylenated (5 OE) oxypropylenated (5 OP) pentaerythritol, and mixtures thereof.

11. The composition as claimed claim 1, in which the particles with release of beneficial agent is obtained according to a process comprising at least the following steps: an aqueous solution formed from a mixture of the water-soluble carbohydrate and/or the water-soluble polyol and of the hydrophobically modified polysaccharide is prepared, the beneficial agent is then added and the whole is stirred so as to form an emulsion; and said emulsion thus formed is homogenized at high pressure at a pressure ranging from 10 to 200 bar; said emulsion is sprayed in a drying chamber; and the water is extracted for a time preferably not exceeding 3 hours, and more preferentially not exceeding 30 minutes, with a fluid under pressure so as to obtain particles with release of beneficial agent.

12. The composition as claimed in claim 1, in which the beneficial agents are chosen from: (i) fatty substances; (ii) fragrancing substances; (iii) pharmaceutical active principles; (iv) cosmetic active agents.

13. The composition as claimed in claim 1, in which the beneficial agents are chosen from fragrancing substances.

14. The composition as claimed in claim 1, in which the particles comprise at least one or more fragrancing substances with a saturating vapor pressure at 25 C. of greater than or equal to 10.0 Pa and said fragrancing substance(s) represent from 50% to 100% by weight relative to the total weight of the fragrancing substances present in the particles.

15. The composition as claimed in claim 1, wherein a) the particles comprise at least one fragrancing substance and b) the composition also comprises at least one fragrancing substance in free form, which may be identical to or different from said fragrancing substance present in said particles.

16. The composition as claimed in claim 1, wherein it exclusively contains one or more fragrancing substances encapsulated in the particles.

17. The composition as claimed in claim 1, comprising at least one coloring agent chosen from nacres, pigments, reflective particles, and mixtures thereof.

18. The composition as claimed in claim 1, comprising at least one deodorant active agent and/or at least one antiperspirant active agent in free form and/or in encapsulated.

19. A process for caring for and/or for the hygiene of and/or for conditioning and/or for fragrancing and/or for making up a human keratin material, which comprises applying to said human keratin material a composition as claimed in claim 1.

20. A cosmetic process for treating body odor and optionally human perspiration, which comprises applying to a keratin material a composition as claimed in claim 17.

21. A consumer product, wherein it is formed from a composition as claimed claim 1.

Description

EXAMPLES OF PREPARING PARTICLES WITH RELEASE OF PERFUME

Example A

(1) Capsules were prepared using the following composition:

(2) TABLE-US-00001 Composition Hydrophobically modified Water-soluble starch polysaccharide Fragrance* Water Example A Amidon Potato 55 g 225 g Capsul from maltodextrin National Starch MD 20 P from 110 g Avebe 110 g

(3) * The perfume used has the following composition:

(4) TABLE-US-00002 Ingredients Amount in g Isopropyl myristate 20.5 Methyl dihydrojasmonate 15 2-Phenylethanol 8 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8- 8 tetramethyl-2-naphthyl)ethan-1-one Hexylcinnamal 6 Tetrahydro-2-isobutyl-4-methylpyran-4- 6 ol Hexyl salicylate 6 Benzyl acetate 5 1,4-Dioxacycloheptadecane-5,17-dione 5 3-Methyl-5-phenyl-1-pentanol 5 Dihydromyrcenol 4 Orange terpenes 0.05% BHT 4 (limonene >95%) 2-Acetonaphthone 2 3a,6,6,9a- 1 Tetramethyldodecahydronaphtho[2,1- b]furan ,-Dimethyl-p-ethylphenylpropanal 1 1,3-Benzodioxole-5-carboxaldehyde 1 2-Isopropyl-5-methylcyclohexanone 1 1-Phenylethyl acetate 0.8 2,6-Dimethylhept-5-enal (Melonal) 0.5 2,4-Dimethylcyclohex-3-ene-1- 0.2 carbaldehyde (Triplal)
Process for Preparing the Emulsion

(5) Potato maltodextrin MD20P and the starch Capsul were mixed in water until dissolved, the perfume was then added and the whole was emulsified with a Heidolph Diax 900 Ultra-Turrax disperser (motor power 900 W with an electronically controlled speed of 8000 to 26 000 rpm) at the maximum power for 4 minutes.

(6) Drying Procedure for Obtaining Spherical Particles

(7) The emulsion obtained was then homogenized at a pressure of 30 bar using a high-pressure pump and then sprayed in an atomization chamber using a nozzle simultaneously with a stream of CO.sub.2 (30 bar, 45 C.) which was circulated continuously at a flow rate of about 500 g/min to remove the water. The dried powder was retained on a filter located at the base of the atomization chamber, and then collected after depressurization. 270 g of spherical microcapsules in the form of a fine white powder with a number-mean diameter of 7.8 m and a volume-mean diameter of 47 m were thus obtained.

(8) The size of the particles was measured via the dry route by laser scattering using a Microtrac S3500 particle size analyzer, the particle sizes being expressed by volume and by number.

(9) TABLE-US-00003 Measured characteristics of the capsules Amount Amount of of free Poured encapsulated perfume powder Absolute perfume (%) (%) density density Example A 19.8 <0.1 484 1.12

Examples B to H

(10) According to the process described in Example A, the following capsules were prepared:

(11) TABLE-US-00004 Composition Hydrophobi- Perfume cally of modified Water-soluble Example starch polysaccharide A Water Example B Amidon Maltodextrin MD 55 g 225 g Capsul from 120 from Tereos National 110 g Starch 110 g Example C Amidon Maltodextrin MD 55 g 225 g Capsul from 170 from Tereos National 110 g Starch 110 g Example D Amidon Maltodextrin MD 55 g 225 g Capsul from 190 from Tereos National 110 g Starch 110 g Example E Amidon Potato maltodextrin 105 g 225 g Capsul from MD 20 P from National Avebe Starch 110 g 110 g Example F Amidon Potato maltodextrin 55 g 225 g Capsul from MD 20 P from National Avebe Starch 66 g 154 g Example G Amidon Potato maltodextrin 55 g 225 g Capsul from MD 20 P from National Avebe Starch 154 g 66 g Example H Amidon Glucose syrup 55 g 225 g Capsul from Glucodry G290 National from Tereos Starch 110 g 110 g

(12) TABLE-US-00005 Measured characteristics of the capsules Amount Poured Amount of of free powder encapsulated perfume density Absolute Examples perfume (%) (%) (g/l) density Example B 19.3 <0.1 568 1.14 Example C 19.4 <0.1 490 1.16 Example D 19.9 <0.1 537 1.11 Example E 38 0.8 482 1.08 Example F 21.0 0.2 595 1.11 Example G 20.7 0.2 521 1.15 Example H 19.2 0.1 568 1.12

Comparative Example I

(13) Capsules having the same composition as Example A as described above were prepared according to the process of Example 1 of U.S. Pat. No. 6,200,949 comprising drying by spray-drying (atomization) of the emulsion.

(14) The emulsion is dried by spray-drying using a Bowen Lab Model Dryer machine using air with a flow rate of 420 m.sup.3/h at a temperature of 204 C. and an external temperature of 93 C. and a turbine speed of 50 000 rpm.

(15) Morphological aspect of the particles obtained: polymorph with aggregates.

Comparative Example J

(16) Capsules having the same composition as Example A as described above were prepared according to the process of Example 1 of U.S. Pat. No. 5,508,259 comprising drying by spray-drying (atomization) of the emulsion.

(17) The mixture was dried by spray-drying with a CCM Sulzer machine at an emulsion flow rate of 50 kg/h, air at a flow rate of 320 m.sup.3/h at 350 C. and 0.45 bar.

(18) Morphological aspect of the particles obtained: polymorph with aggregates.

(19) TABLE-US-00006 Measured characteristics of the capsules Amount Poured Amount of of free powder encapsulated perfume density Absolute Composition perfume (%) (%) (g/l) density Example I 18.3 2.7 259 1.16 (outside the invention) Example J 11.2 1.7 269 1.12 (outside the invention)

FORMULATION EXAMPLES

Example 1

Deodorant and Antiperspirant Product

(20) A deodorant and antiperspirant having the following composition was prepared:

(21) TABLE-US-00007 Amounts in Ingredients (INCI name) % by weight Oxypropylenated (14 OP) butyl alcohol 5.9 Isopropyl palmitate 25.4 Polyethylene glycol distearate (8 OE) 6.2 Glycine-buffered aluminum/zirconium 19.0 tetrahydroxychloride complex Calcium hydroxide 0.5 Polyethylene wax (MW: 500) 11.4 Polydimethylsiloxane (viscosity: 10 cSt) 22.2 Ozokerite 2.6 Perlite (25 microns) 0.2 Capsules of perfume of Example A 6.7 TOTAL 100

(22) Isopropyl palmitate and oxypropylenated butyl alcohol are placed in a tank. The mixture is heated to 65 C. and the other ingredients are then added (one by one) while remaining at 65-70 C. The whole is homogenized until a homogeneous solution is obtained, for about 15 minutes. The perlite and the perfume capsules of Example A are added and the mixture is then cooled to about 55 C. (a few C. above the thickening point of the mixture) and poured into sticks, which are stored in a refrigerator at 4 C. for 30 minutes.

Examples C1 and C2

(23) In a manner similar to that of Example 1, deodorant antiperspirant sticks having the following compositions were prepared:

(24) TABLE-US-00008 Example C1 (outside the invention) Ingredients (% by weight) Oxypropylenated butyl alcohol 5.9 Isopropyl palmitate 25.4 Polyethylene glycol distearate 6.2 Glycine-buffered aluminum/zirconium 19.0 tetrahydroxychloride complex Calcium hydroxide 0.5 Polyethylene wax 11.4 PDMS 22.2 Ozokerite 2.6 Perlite 0.2 Capsules of perfume of Example I 6.7 TOTAL 100

(25) TABLE-US-00009 Example C2 (outside the invention) Ingredients (% by weight) Oxypropylenated butyl alcohol 5.9 Isopropyl palmitate 25.4 Polyethylene glycol distearate 6.2 Glycine-buffered aluminum/zirconium 19.0 tetrahydroxychloride complex Calcium hydroxide 0.5 Polyethylene wax 11.4 PDMS 22.2 Ozokerite 2.6 Perlite 0.2 Capsules of perfume of Example J 6.7 TOTAL 100
Evaluation of the Examples
Evaluation Protocol:

(26) About 0.2 g of composition was deposited uniformly onto a perfume blotter (reference from Granger Veyron: 40140BCSI of size 4 cm14 cm). After 1 minute, the perfume odor intensity was evaluated. Perspiration was then simulated by adding about 0.1 g of water (three sprays) onto the deposited composition. After waiting for 1 minute, the blotter was smelled again.

(27) TABLE-US-00010 Formulation Odor intensity BEF Odor intensity AFT Example 1 Odorless Very strong perfume odor Example C1 Strong perfume odor Very strong perfume odor Example C2 Strong perfume odor Strong perfume odor BEF = before addition of water; AFT = after addition of water

(28) It was thus observed at T.sub.0 that the formula of Example 1 comprising the perfume capsules according to the invention has no odor before the addition of water, in contrast with Examples C1 and C2 (outside the invention), which shows that the perfume capsules in Examples C1 and C2 are not leaktight before the addition of water.

(29) It was also observed that the composition of Example, 1 after stimulation with water, led to a very intense odor, which demonstrates substantial release of perfume in response to the water stimulus.

Example 2

Preparation of an Antiperspirant Stick Having the Following Composition

(30) TABLE-US-00011 Ingredients Amounts in weight % Cyclopentasiloxane 20.0 (DC245 - Dow Corning) Hexyldecyl stearate 14.0 (Eutanol G16 S - Cognis) PPG-14 butyl ether 5.0 Hydrogenated castor oil 6.0 (Cutina HR - Cognis) Cetearyl alcohol 8.0 Cetearyl alcohol/Ceteareth-30 14.0 80/20 (Sinnowax AO - Cognis) Talc 7.0 Microdry Aluminum Chlorohydrate 20.0 Capsules of perfume of Example G 6.0 Total 100

(31) The capsules of perfume of Example G may be replaced with the capsules of Examples A to F and H described previously.

(32) The cyclopentasiloxane is heated to 65 C. The other ingredients are added (one by one), while remaining at 65-70 C. The whole is homogenized (transparent solution) for 15 minutes. The two deodorant active agents and the capsules of Example G are added. The mixture is cooled to about 55 C. (a few C. above the thickening point of the mixture) and poured into sticks, which are stored in a refrigerator at 4 C. for 30 minutes.

(33) The intensity of the perfume odor on the skin was evaluated at T0, T2h and T6h after application of the composition.

(34) About 0.15 g of the composition of Example 2 was applied to the skin. After 1 minute, the intensity of the perfume odor was evaluated (BEF), and was graded from 0 to 10. About 0.1 g of water (three sprays) were then sprayed onto the composition applied to the skin. After waiting for 30 seconds, the intensity of the perfume odor was evaluated (AFT).

(35) 2 and 6 hours later, the intensity of the odor was re-evaluated (BEF) before adding about 0.1 g of water (three sprays) to the composition applied to the skin. After waiting for 30 seconds, the intensity of the odor was evaluated (AFT).

(36) TABLE-US-00012 Odor intensity Odor intensity Odor intensity T0h T2h T6h Product BEF AFT BEF AFT BEF AFT Example 2 1.0 5.0 4 3.0 5.5 2.5 2.5 4.5 2.0 BEF = before addition of water; AFT = after addition of water = amplitude of difference in olfactory intensity (BEF AFT) Scale of perfume odor intensity: 0 to 10 (0 = odorless; 10 = very intense/saturated odor).

(37) It was thus observed at T0 that, on the skin, the composition of Example 2 has a virtually odorless odor. It was also observed that each spraying of water onto the product at T0, T2h and T6h leads to an increase in the perfume odor intensity, which demonstrates substantial release of perfume.

Example 3

(38) In a manner similar to that of Example 2, an antiperspirant stick having the following composition was prepared:

(39) TABLE-US-00013 Ingredients % by weight Cyclopentasiloxane 20.6 (DC245 - Dow Corning) Hexyldecyl stearate 14.0 (Eutanol G16 S - Cognis) PPG-14 butyl ether 5.0 Hydrogenated castor oil 6.0 (Cutina HR - Cognis) Cetearyl alcohol 8.0 Cetearyl alcohol/Ceteareth-30 14.0 80/20 (Sinnowax AO - Cognis) Talc 7.0 Aluminium chlorohydrate 20.0 (Micro Dry) Capsules of perfume of Example A 5.0 Free perfume 0.4 Total 100

(40) The capsules of perfume of Example A may be replaced with the capsules of Examples B to H described previously.

(41) The intensity of the perfume odor on the skin was evaluated at T0, T2h and T6h after application of the composition according to the protocol described in Example 2.

(42) TABLE-US-00014 Odor intensity Odor intensity Odor intensity T0h T2h T6h Product BEF AFT BEF AFT BEF AFT Example 3 5.0 6.5 1.5 4.0 6.0 2.0 3.0 6.0 3.0

(43) It was thus observed at T0 that the composition of Example 3 has a perfume odor of moderate intensity. It was also observed at each time (T0, T2h and T6h) that the spraying of water onto the product leads to an increase in the perfume odor intensity (especially of the fresh notes), which demonstrates substantial release of perfume.

Example 4

Preparation of an Antiperspirant Stick Having the Following Composition

(44) TABLE-US-00015 % by Ingredients weight Polyethylene wax (Performalene 500-L polyethylene (New 4.1 Phase Technologies) Ethylene homopolymer (Performalene 400 Polyethylene - 8.3 New Phase Technologies) Cyclohexadimethylsiloxane 25.4 (Dow Corning 246 Fluid - Dow Corning) Phenyl trimethicone (Dow Corning 556 Cosmetic Grade Fluid - 18.6 Dow Corning) Isohexadecane 19.6 Methyl methacrylate crosspolymer (Ganzpearl GMP 0820 - 13.0 Ganz Chemical) Expanded milled perlite (Optimat 1430 OR - Word Minerals) 4.5 Micronized zinc pyrrolidonecarboxylate (UCIB - Solabia) 0.5 Capsules of perfume of Example G 6.0 Total 100

(45) The capsules of perfume of Example G may be replaced with the capsules of Examples A to F and H described previously.

(46) The cyclohexadimethylsiloxane is heated to 65 C. The other ingredients are added (one by one) while remaining at 65-70 C. The whole is homogenized until a transparent solution is obtained, for about 15 minutes. The zinc pyrrolidonecarboxylate, the perlite and the perfume capsules of Example G are added and the mixture is then cooled to about 55 C. (a few C. above the thickening point of the mixture) and poured into sticks, which are stored at 4 C. for 30 minutes.

(47) The composition applied to the armpits leaves a deposit on the skin which gives off a perfume odor. The perfume is released in the course of the day when the capsules are in contact with perspiration.