METHOD OF CONDUCTING A MINIMALLY INVASIVE SURGICAL PROCEDURE AND RKH-I APPARATUS FOR THE IMPLEMENTATION THEREOF

Abstract

An automatic robotic apparatus for conducting a minimally invasive surgical procedure includes a robotic arm having a movable member made as the multilink active actuator. The end portion of the multilink active actuator is provided with the connector to which the hollow head for a needle biopsy is attached. The operation of the U-shaped head is under full control of the robotic apparatus computer system. Results of pre-procedure studies of a site of interest and the progression of the surgical procedure are displayed on a monitor of the computer system.

Claims

1. An automatic robotic apparatus for conducting a minimally invasive surgical procedure, comprising: a robotic arm which movable member comprises a means for conducting a transcutaneous needle biopsy, the surgical procedure of which being controlled by a computer system, and the course of which being displayed on the monitor screen, wherein robotic arm contains a pressurized anesthetic and a pressurized antiseptic, a means used for giving deep anesthesia, and a control unit cooperating with servo drives mechanically controlling the movable member and the means for conducting a transcutaneous needle biopsy, being comprised of a U-shaped head accommodating an output through hole for delivering an anesthetic and an antiseptic for surface anesthesia, a guide needle for intratissular anesthesia, a guide needle for a needle biopsy, and a control unit for said needles; a the computer system receiving and processing virtual CT slices of a focal mass that are transmitted by the CT scanner computer system and mapping out and subsequently modeling a minimally invasive surgical procedure.

2. The automatic robotic apparatus, according to claim 1, wherein an antiseptic and an anesthetic are contained in aerosol cylinders.

3. The automatic robotic apparatus according to claim 1, wherein the robotic arm is fixedly attached to the floor or to the ceiling.

4. The automatic robotic apparatus according to claim 1, wherein the robotic arm being comprised of movable wheels so as to be mobile.

5. The automatic robotic apparatus according to claim 1, wherein the robotic arm is provided with an emergency stop means triggered by pushing an instant shutoff button.

6. The automatic robotic apparatus according to claim 1, wherein the means used for giving deep anesthesia is comprised of a piston mechanism with an electric motor.

7. The automatic robotic apparatus according to claim 6, wherein the piston mechanism is arranged in a cylindrical container.

8. The automatic robotic apparatus according to claim 1, wherein the movable member of the robotic arm is comprised of an active multilink actuator.

9. A method of conducting a minimally invasive surgical procedure, comprising the steps of: evaluating location and parameters of a focal mass; selecting a needle biopsy site with the aid of a CT scan; and conducting a transcutaneous needle biopsy of a focal mass with the aid of a biopsy needle, wherein virtual CT slices, as produced by the CT scanner computer system, are sent to the computer system of the automatic robotic apparatus performing a minimally invasive surgical procedure, which system performs mapping out the course of and modeling a needle biopsy, and said 3D virtual CT slices, as received by it, are subjected to a computerized analysis for the purposes of automatically establishing optimal parameters and conditions of conducting a robotic surgical procedure performed by the U-shaped head of the robotic arm movable member, the U-shaped head accommodating a biopsy needle and a unit of mechanisms for controlling it mechanically; upon completion of determining said parameters and conditions, the U-shaped head contacts an area of the patient's skin, surface and intratissular anesthesia of said area is performed, and then the biopsy needle is advanced through the skin in order to collect a tissue sample, everything being conducted in accordance with the established parameters and conditions of the corresponding surgical procedure during which a CT scanner scans it and depicts its course on a computer system monitor.

10. The method of conducting a minimally invasive surgical procedure according to claim 9, wherein 3D virtual CT slices of a focal mass are subjected to a computerized analysis for the purposes of automatically determining a virtual area of a contact between the U-shaped head and the patient's body surface, planning and modeling a safe advancement of the active multilink actuator to the contact area, determining entry points and routes of the guide needle for intratissular anesthesia, and determining steps of surface anesthesia and intratissular anesthesia as well as a site and routes of the biopsy needle for the purpose of collecting a tissue sample.

11. The method of conducting a minimally invasive surgical procedure according to claim 10, wherein the entry points for the guide needle for intratissular anesthesia and those for the biopsy needle are determined by identifying the air-skin edge under a HU density.

12. The method of conducting a minimally invasive surgical procedure according to claim 10, wherein routes of the needle for intratissular anesthesia are determined by a difference between densities of the skin and the muscular tissue layers.

13. The method of conducting a minimally invasive surgical procedure according to claim 12, wherein routes for the needles are determined with the possibility of correcting the procedure course by the operator.

14. The method of conducting a minimally invasive surgical procedure according to claim 10, wherein routes for the biopsy needle are determined with due regard to the possibility of exerting a minimum action on the patient's vessels and critical organs.

15. The method of conducting a minimally invasive surgical procedure according to claim 14, wherein minimum action on the patient's vessels and critical organs is ensured by conducting a CT scan with intravenous contrasting or by conducting a MRI procedure.

16. The method of conducting a minimally invasive surgical procedure according to claim 9, wherein, in order to monitor the patient's respiration, a means for monitoring the chest excursion is connected to the robotic arm, and a strap monitoring changes in the chest volume is attached to the patient.

17. The method of conducting a minimally invasive surgical procedure according to claim 16, wherein medical glasses are put on the patient's eyes, which glasses display data on his/her respiration during scanning and in the real-time mode.

18. The method of conducting a minimally invasive surgical procedure according to claim 17, wherein the patient makes an inhalation that is equal in depth to an inhalation during scanning.

19. The method of conducting a minimally invasive surgical procedure according to claim 9, wherein the robotic arm is calibrated according to the CT scanner coordinates before setting up parameters and conditions of a surgical procedure to be conducted.

20. The method of conducting a minimally invasive surgical procedure according to claim 19, wherein said calibration is carried out with the aid of the U-shaped head which, under the action of the active multilink actuator of the robotic arm, is moved until its marks are matched with those of the CT scanner lasers; and then the robotic arm is fixed in place by retainers.

21. An apparatus for conducting a transcutaneous needle biopsy, comprising: a biopsy needle arranged within a hollow head U-shaped in a cross-section and having an open base that is fixed on a patient's skin area, wherein the head is made with a width variable relative to its height, the width of its base being increased toward said patient's skin area, and wherein the head accommodates an output through hole for delivering an anesthetic and an antiseptic for surface anesthesia, and a guide needle for intratissular anesthesia and a mechanism unit for controlling delivery of surface anesthesia and said needles, the control being affected in accordance with automatically preset optimal parameters and conditions of conducting a robotic transcutaneous needle biopsy.

Description

BRIEF DESCRIPTION OF THE SEVERAL VIEWS OF THE DRAWINGS

[0080] FIG. 1 shows a general schematic view of the proposed automatic robotic apparatus connected to a CT scanner with its own computer system.

[0081] FIG. 2 shows a longitudinal sectional view of the proposed head for conducting a surgical procedure, such as a needle biopsy.

[0082] FIG. 3 shows an image of a CT virtual slice depicting automatic planning of the biopsy needle advancement trajectory.

[0083] FIG. 4 shows an image of a virtual CT slice depicting biopsy needle advancement in the real-time mode.

DETAILED DESCRIPTION OF THE INVENTION

[0084] Below, the proposed group of inventions is explained by a specific embodiment which, nevertheless, is not a single possible one, but is used for clear demonstration of a way how the totalities of essential features may achieve the objectively arising technical effect that solves the technical task as set for the group of inventions.

[0085] The proposed automatic robotic method of conducting a minimally invasive surgical procedure utilizes the following devices and members: [0086] a CT scanner 1; [0087] a CT scanner table 2; [0088] a CT scanner computer system 3; [0089] a robotic apparatus computer system 4; [0090] a CT scanner gantry aperture 5; [0091] a robotic arm 6; [0092] an active multilink actuator 7; [0093] a robotic arm case 8; [0094] aerosol cylinders 9 for an anesthetic and an antiseptic; [0095] a piston mechanism 10 for surface anesthesia; [0096] rubber tubes 11; [0097] active actuator links 12; [0098] a connector 13; [0099] a hollow head 14 for a needle biopsy; [0100] a piston mechanism electric motor 15; [0101] servo drives 16; [0102] a through hole 17 for delivery of surface anesthesia drugs; [0103] a guide intratissular anesthesia needle 18; [0104] a puncture needle 19 for a needle biopsy; [0105] a mechanism control unit 20 controlling said needles and delivery of surface anesthesia drugs.

[0106] An automatic robotic apparatus for conducting a minimally invasive surgical procedure comprises the robotic arm 6 which movable member is made as the multilink active actuator 7. The end portion of the multilink active actuator 7 is provided with the connector 13 to which the hollow head 14 for a needle biopsy is attached.

[0107] The operation of the U-shaped head 14 is under full control of the robotic apparatus computer system 4. Results of pre-procedure studies of a site of interest and the progression of the surgical procedure are displayed on a monitor of the computer system 4.

[0108] The robotic arm 6 comprises the aerosol cylinders 9 with a pressurized anesthetic and a pressurized antiseptic, a means for storage and delivery of deep anesthesia drugs that is made as the piston mechanism 10 provided with the electric motor 15 and a control unit (not shown in the Figures).

[0109] This control unit cooperates with the servo drives 16 capable of mechanically controlling the active multilink actuator 7 and the hollow U-shaped head 14 directly used for conducting a minimally invasive surgical procedure, namely, a needle biopsy procedure.

[0110] The hollow U-shaped head 14 accommodates the output through hole 17 intended for delivery of an anesthetic and an antiseptic for surface anesthesia, the guide intratissular anesthesia needle 18, a guide needle 19 for a needle biopsy, and a control mechanism unit for the needles and delivery of the surface anesthesia drugs.

[0111] The robotic apparatus computer system 4 is made capable of receiving and processing virtual CT slices of a focal mass that are transmitted by the CT scanner computer system 3 and capable of mapping out the course and subsequently modeling a minimally invasive surgical procedure with the aid of a special software.

[0112] The robotic arm 6 is equipped with an emergency stop means triggered by pushing an instant stop button (not shown in the Figures).

[0113] The proposed group of inventions may be implemented as follows. The proposed automatic robotic apparatus consists, in essence, of the movable robotic arm 6 being controlled by the computer system 4.

[0114] Before starting a procedure with the movable automatic robotic apparatus, it should be calibrated in accordance with the coordinates of the CT scanner 1. However, when the apparatus is stably fixed, no calibration before each minimally invasive surgical procedure is required.

[0115] After calibration of the proposed automatic robotic apparatus, the CT scanner isocenter is taken as the zero point (x0; y0; z0). Movements are effected along the Y and X axes due to movements of the active multilink actuator 7. The limitations are the size of the gantry aperture of the CT scanner 1 and the size of the U-shaped head 14 arranged at the end of the active multilink actuator 7. Movements along the Z axis are effected due to movements of the CT scanner table 2. After calibration, the coordinate x0y0z0 corresponds to the tip of the biopsy needle 19. After receiving data on a patient, the robotic apparatus computer system 4 receives images in the DICOM format from the CT scanner computer system 3. The patient's body edges are determined by a difference in an air-tissue density in the HU units. Also, possible coordinates are determined for safe manipulative movements of the active multilink actuator 7 and the U-shaped head 14 of the robotic arm 6 in the CT scanner aperture.

[0116] In order to conduct a calibration procedure when the automatic robotic apparatus is movable, the operator arranges it near the CT scanner 1 and moves the active multilink actuator 7 with the U-shaped head 14 until the marks on the U-shaped head 14 are aligned with the lasers of the CT scanner 1. The arranged automatic robotic apparatus is fixed in place by retainers. The active multilink actuator 7 with the U-shaped head 14 is moved out from the aperture of the CT scanner 1 and stays in the initial position so as not to interfere with the course of the patient scanning.

[0117] Then the patient is fully undressed, laid onto the CT scanner table 2 and scanned with the aid of the CT scanner 1 in the supposed area of a minimally invasive surgical procedure. An excursion control sensor is turned on for scanning of the patient's mobile organs. Series of virtual CT slices of a focal mass, as produced by the CT scanner computer system, are sent to the robotic apparatus computer system 4 which is used for mapping out the course of and modeling a needle biopsy procedure (with the aid of a special software). The 3D virtual CT slices, as received by the robotic apparatus computer system 4, are subjected to a computerized analysis for the purposes of automatically setting up optimal parameters and conditions for a robotic surgical procedure (with the aid of a special software), namely, the robotic apparatus computer system 4 determines in a 3D projection on said virtual CT slices: [0118] a point of virtual contact between the hollow U-shaped head 14 and the patient's body (the automatic robotic apparatus performs planning and modeling of an accurate and safe movement of the active multilink actuator 7 to the contact area); [0119] an area where the hollow U-shaped head contacts the patient; [0120] points of entry are determined for the guide intratissular anesthesia needle 18 and the biopsy needle 19, and all anesthesia steps required are determined with due regard to individual specific features of each patient; [0121] an optical trajectory for advancing the biopsy needle 19 is determined.

[0122] Points of entry for the needles 18 and 19 are determined by finding the air-skin edge according to a HU density. Routes for the intratissular anesthesia needle 18 are determined by a difference between densities of the skin and the muscular tissue layers. Routes for the biopsy needle 19 are determined with due regard to the possibility of minimum action on vessels and critical organs. Routes for the needles 18, 19 are determined with the possibility of correcting the procedure course by the operator. In order to ensure minimum action on vessels and critical organs, a scan with the aid of the CT scanner 1 may be conducted with intravenous contrasting. Moreover, in some cases respiration may be monitored.

[0123] In order to monitor respiration, before conducting a biopsy procedure on complex movable areas a sensor for chest excursion (not shown in the Figures) is connected to the automatic robotic apparatus. A strap is attached to the patient, which monitors changes in the chest volume. Also, glasses are put onto the patient's eyes beforehand, which depict a curve of his/her respiration during a scan, and a respiration curve in the real time mode. During a scan the patient should make an inhalation equal to his/her inhalation depth. However, as it is said above, it may be done in extreme cases, during a chest biopsy procedure only, and may not be practiced for patients of advanced age who have difficulties with such a manipulation.

[0124] After that, the proposed automatic robotic apparatus starts conducting a minimally invasive surgical procedure with preset optimal conditions and parameters.

[0125] During the whole procedure the automatic robotic apparatus is connected to the CT scanner 1 and is capable of exercising full control over the CT scanner 1, in particular for ensuring the possibility of controlling the table 2 and monitoring its angle of inclination, and for ensuring the possibility of conducting a scan.

[0126] After the planning procedure is completed, the needle biopsy procedure is started and calculated. The size of the hollow U-shaped head 14 depends on the type of a biopsy needle 19 selected, which length may vary in the range from 10 to 30 cm, the size of the gantry aperture of the CT scanner 1 is 70 cm. Then, the patient on the table 2 of the CT scanner 1 is moved so as to provide a space required for a needle biopsy procedure. In some rare cases, this manipulation may require to move him/her to a side, or to the belly. The robotic arm 6 determines a distance from the patient's surface to the maximum upper point of the aperture 5, using HU data. In a case where such a distance is insufficient for conducting a minimally invasive surgical procedure, the robotic arm 6 issues instructions to move the patient further, until this distance is sufficient for accurate and safe movement of the active multilink actuator 7 of the robotic arm 6. When the active multilink actuator 7 with the hollow U-shaped head 14 is within the aperture 5 of the CT scanner 1, the hollow U-shaped head 14 contacts the skin surface, thus activating the pressure sensor, and the robotic arm 6 stops moving. Then, the CT scanner 1 may change, if necessary, the angle of inclination of the table 2 and, at the same time, the positioning angle of the hollow U-shaped head 14. It is important that, if during the planning procedure the CT scanner 1 was inclined toward the patient's legs while the patient lies with his/her head in the gantry of the CT scanner, the robotic arm 6 change its position correspondingly to maintain the access to the aperture 5. In such a case the movable robotic arm 6 should be positioned correspondingly and the calibration procedure should be repeated.

[0127] When all the conditions and parameters are matched between the CT scanner 1 and the robotic arm 6 for a successful and reliable procedure, in particular an angle of inclination of the table 2 and an optimal distance between the robotic arm 6 and the gantry of the CT scanner 1, scanning is conducted, namely, the CT scanner 1 conducts one scan in order the operator may inspect the position of the hollow U-shaped head 14. The course of the procedure is depicted on the control scan. Then, an antiseptic for disinfection of the surface and an anesthetic for surface anesthesia are ejected from the aerosol cylinders 9 and, if necessary, from the piston mechanism 10, said antiseptic and anesthetic are moved via the rubber tubes 11, passed within the active multilink actuator 7, enter, via the connector 13, into the hollow U-shaped head 14, specifically into the through hole 17 intended for ejecting the surface anesthesia drugs onto the fixed area of the patient's skin.

[0128] Then, the guide needle 18 is advanced for giving intratissular anesthesia and enters under the patient's skin. At this time a control scan is conducted. The operator evaluates the parameters and conditions in the position of the needle 18. Then, the intratissular anesthesia needle 18 is advanced under the skin layer-by layer, introducing the anesthetic in accordance with the preset parameters and conditions. At this time the CT scanner 1 continues making control scans. Upon completion of the anesthesia procedure, the intratissular anesthesia needle 18 is accurately returned to the initial position. Then, the biopsy needle 19 is advanced for conducting a needle biopsy procedure by moving it to the site of interest for collecting a sample. During this, the CT scanner 1 conducts scanning of the manipulation course and displays all the actions on the monitor screen of the robotic apparatus computer system 4. As soon as the biopsy needle 19 reaches the selected point, a sample is collected, and the needle is returned to the initial position.

[0129] If selected sites require respiration monitoring, the procedure is conducted in synchronization with respiration according to a respiration curve registered before. The robotic arm 6 conducts the manipulation at the time when the real-time curve coincides with the loaded one, and the patient is moved according to the HU evaluation for the site selected. If the patient has moved, the robotic arm 6 will issue a corresponding signal.

[0130] It is important to note in this point that the active multilink actuator 7 has several links for ensuring mobility. The cables, shafts, hollow tubes, which connect the robotic arm 6 to the hollow U-shaped head 14, are carried out by the active multilink actuator 7. The connector 13, which is arranged on the end of the active actuator 7, is made with the possibility of coupling its mechanisms with the hollow U-shaped head 14 in order the latter may perform certain movements (straight, rotational, etc.) and move the needles 18 and 19 and deliver medical preparations (for anesthesia) and make other, preset movements and rotations in accordance with the preset parameters and conditions for conducting a successful and reliable needle biopsy procedure.

[0131] For an unforeseen emergency situation, such as a blackout, a strong movement of the patient, an error during the procedure, etc., the robotic arm 6 is equipped with the emergency stop button. It should be pressed for turning off the power supply to the mechanisms involved in the proposed minimally invasive surgical procedure, and in such a case the needles 18 and 19 are returned to their respective initial positions under the action of their respective springs, and the servo drives 16 may rotate freely when the power is shut off.

EXAMPLE 1

[0132] A man aged 47.

[0133] A neoplasm in the upper lobe of the right lung with a size up to 0.5 cm was identified during a planned X-ray study of the chest organs. The patient was directed to a hospital for further examination.

[0134] St. praesens: temperature36.7, respiratory rate22 breaths per minute, heart rate71 beats per minute.

[0135] General analysis of urea and bloodno changes.

[0136] Complaints: does not make actively.

[0137] Bad habits: smoking from the age of 12.

[0138] A puncture under the X-ray radiography control is difficult due to a small size of a neoplasm. The patient was subjected to a control CT study, during which a neoplasm of rounded shape with the size of up to 0.5 cm was identified in the upper lobe of the right lung.

[0139] No other changes in the chest organs were identified. A decision was taken to conduct a needle biopsy of this site according to the proposed minimally invasive surgical procedure under control of a CT scanner. The data obtained by the CT scanner were transmitted to the control computer system of the automatic robotic apparatus, which was used for modeling and mapping out the course of the needle biopsy procedure, and optimal parameters and conditions for the procedure were determined.

[0140] The data was transmitted to the automatic robotic apparatus (the robotic arm 6 with the computer system 4) that conducted the procedure, using the hollow U-shaped head 14 for a needle biopsy. During the manipulation the CT scanner 1 continuously scanned the entire course of the procedure for exercising control over important advancements of the intratissular anesthesia needle 18 and the biopsy needle 19; anesthesia was made also. In this way, reliable data (images) on hitting the focal mass with the needle 19 was obtained, and a sample of a histological material was collected therefrom. The sample was sent to a laboratory for analysis. An epidermoid carcinoma was identified.

[0141] Diagnosis: an epidermoid carcinoma in the upper lobe of the right lung.

[0142] The proposed method enabled to identify a carcinoma in the lung that was accidentally found during the planned examination. An immediate needle biopsy of small masses is possible only with the use of the proposed automatic robotic system (the robotic arm 6 with the computer system 4), since it is operated in connection with the CT scanner 1, is clearly and reliably oriented according to coordinates and takes the patient's chest excursion into account, which enables to reliably and successfully conduct a needle biopsy of small masses that are inaccessible in an X-ray study.

[0143] No damage of critical organs was identified, the patient had minimum painful sensations, and no infection was determined.

EXAMPLE 2

[0144] A man aged 57.

[0145] Arrived with complaints of the skin icteritiousness, fever, general malaise, weight loss, changed color of feces and urea. The patient was placed in a hospital, a cholelithiasis suspected. A US-procedure identified a small concrement in the gallbladder projection and an enlargement of the intrahepatic bile ducts. In order to specify the cause of said enlargement of the intrahepatic bile ducts, the patient was subjected to MR cholangiography. A enlargement of the intrahepatic bile ducts with an obstruction in the bifurcation of the common hepatic duct was found, and a neoplasm in this site was suspected.

[0146] It was not possible to conduct a biopsy procedure under the US-control for the patient due to a great volume of gas in the intestines, typical stone artifacts in the gallbladder and problems with imaging of the point of narrowing. A CT scan with intravenous contrasting was conducted which identified an accumulation of the contrast preparation in the projection of the common hepatic duct. The data obtained from the CT scanner was transmitted to the computer system 4 used for controlling the automatic robotic system that performed modeling and mapping out the needle biopsy procedure and determined optimal parameters and conditions for the needle biopsy procedure.

[0147] The data was transmitted to the automatic robotic apparatus (the robotic arm 6 with the computer system 4) that conducted the procedure, using the hollow U-shaped head 14 for a needle biopsy.

[0148] During the manipulation the CT scanner 1 continuously scanned the entire course of the procedure for exercising control over important advancements of the intratissular anesthesia needle 18 and the biopsy needle 19; anesthesia was given as well. In this way reliable data (images) on hitting the focal mass with the needle 19 was obtained, and a sample of a histological material was collected therefrom. The sample was sent to a laboratory for analysis.

[0149] Histology: high-differentiated adenocarcinoma.

[0150] In the result of the needle biopsy procedure an early-stage mass was identified in a point awkward for a needle biopsy under the US-control.

[0151] The needle biopsy procedure was conducted accurately and reliably, no critical organs were damaged, no painful sensations were experienced, no breaks of the skin integrity were made. The patient quickly recovered after this procedure.

EXAMPLE 3

[0152] A girl aged 18.

[0153] Arrived in a hospital with complaints of weakness, general malaise, temperature rise to 37.5. When evaluating a chest organ X-ray picture, a mediastinal lymphadenopathy was suspected. A CT scan of the chest organs was recommended. A CT scan may identify a mediastinal lymphadenopathy for all groups of the lymph nodes. In order to specify the diagnosis, it was decided to conduct a needle biopsy of the intrathoracic lymph nodes with the use of the proposed method of conducting minimally invasive surgical procedure, because no differentiation of the intrathoracic lymph nodes may be made on a conventional X-ray picture, and the ultrasonic technique is unavailable for a needle biopsy of the mediastinum.

[0154] The data obtained from the CT scanner was transmitted to the computer system 4 used for controlling the automatic robotic system that performed modeling and mapping out of a needle biopsy procedure and determined optimal parameters and conditions for that needle biopsy procedure.

[0155] The data was transmitted to the automatic robotic apparatus (the robotic arm 6 with the computer system 4) that conducted the procedure, using the hollow U-shaped head 14 for a needle biopsy.

[0156] During the manipulation the CT scanner 1 continuously scanned the entire course of the procedure for exercising control over important advancements of the intratissular anesthesia needle 18 and the biopsy needle 19; anesthesia was given as well. In this way reliable data (images) on hitting the focal mass with the needle 19 was obtained, and a sample of a histological material therefrom was collected reliably and successfully. The sample was sent to a laboratory for analysis.

[0157] The obtained material was transmitted for a histological study, the conclusionnoncaseified epithelioid granulomas.

[0158] Diagnosis: sarcoidosis.

[0159] This method of a needle biopsy enables to puncture structures with high accuracy and under continuous control by a doctor, but without his/her direct intervention, which provides the possibility of studying areas with adjoining vitally important organs without the risk of complications.

[0160] During the procedure no critical organs were affected, the skin integrity was not violated, no infection development was found.

EXAMPLE 4

[0161] A woman aged 45.

[0162] An excerpt from the anamnesis: resection of the left kidney due to a renal cell carcinoma. She was subjected to a planned examination on a CT scanner, a neoplasm was found in the left adrenal gland.

[0163] The proposed method was selected for a needle biopsy, since it was extremely difficult to image the adrenal glands by an ultrasonic scanning. The sample collected during the biopsy procedure showed a metastasis of a renal cell carcinoma.

[0164] The data obtained from the CT scanner was transmitted to the computer system 4 used for controlling the automatic robotic system that performed modeling and mapping out a needle biopsy procedure and determined optimal parameters and conditions for that needle biopsy procedure.

[0165] The data was transmitted to the automatic robotic apparatus (the robotic arm 6 with the computer system 4) that conducted the procedure, using the hollow U-shaped head 14 for a needle biopsy.

[0166] During the manipulation the CT scanner 1 continuously scanned the entire course of the procedure for exercising control over important advancements of the intratissular anesthesia needle 18 and the biopsy needle 19; anesthesia was given as well. In this way reliable data (images) on hitting the focal mass with the needle 19 was obtained, and a sample of a histological material therefrom was collected reliably and successfully. The sample was sent to a laboratory for analysis.

[0167] The proposed method may be used for puncturing masses in hardly accessible sites quickly and operatively, without risks of complications and without any complex preliminary preparation.

[0168] No complications and infections were identified in the patient, the skin integrity was not violated.

[0169] According to the patient, her general state was good, the recovery was quick.

EXAMPLE 5

[0170] A man aged 33.

[0171] Arrived with complaints of weakness, poor appetite, weight loss.

[0172] An excerpt from the anamnesis: HIV-infected.

[0173] No pathology was found on an X-ray picture of the chest organs, An ultrasonic scanning of the abdominal cavity organs and the small pelvis organs showed the normal state. During a MRI procedure single enlarged lymph nodes partially fused in conglomerates were found in the small pelvis. Due to poor imaging during an ultrasonic scanning, a decision was taken to use the proposed method under the CT scanner control. During mapping out the course of and modeling the procedure itself in the computer system the data obtained from the CT scanner was superposed, which facilitated imaging of masses in the small pelvis and determining access points for the biopsy needle 19 and the guide needle 18 for intratissular anesthesia.

[0174] During the manipulation the CT scanner 1 continuously scanned the entire course of the procedure for exercising control over important advancements of the intratissular anesthesia needle 18 and the biopsy needle 19; anesthesia was given as well. In this way reliable data (images) on hitting the focal mass with the needle 19 was obtained, and a sample of a histological material was collected therefrom reliably and successfully. The sample was sent to a laboratory for analysis.

[0175] After the conducted study a tissue sample was obtained. Histology: epithelioid cells and Pirogov-Langhans giant cells present specifically against the background of lymphoid and reticular tissue hyperplasia.

[0176] Diagnosis: tuberculosis.

[0177] This Example shows that the proposed method may be used for conducting complex biopsy procedures without direct involvement of a surgeon, which enables not to tear personnel from medical practice for conducting diagnostic actions, a harmful action of X-radiation as well as possible harmful actions on personnel in connection with this complex manipulation are precluded, and the possibility of infection entering into a site of a direct minimally invasive surgical procedure is significantly reduced.

[0178] According to the patient, he did not experience painful sensations during the procedure, his general state was good after the procedure.

EXAMPLE 6

[0179] A man aged 53.

[0180] Arrived in a hospital for specifying his diagnosis.

[0181] An excerpt from the anamnesis: smoking since 18 years of age.

[0182] He considered himself ill for three months since the date when he felt weakness, malaise, rise of temperature to 37.5 degrees and cough accompanied with blood excretion appeared.

[0183] An X-ray study was immediately conducted during which a mass was identified in the upper lobe of the left lung, having the size up to 8 mm and an irregular structure with radial contours and a cavity in the center. A CT scan was conducted that identified a similar object and enlarged mediastinal lymph nodes on both sides. A decision was taken to conduct a needle biopsy of this mass under X-ray control. A sample sent for a histological study was not informative.

[0184] The second needle biopsy under X-ray control was conducted, the histological report stated that the picture corresponded to inflammatory changes in the lung tissue.

[0185] The initial diagnosis of tuberculosis was made for the patient.

[0186] A control CT scan was scheduled for conducting in 2 weeks. During this period the general state was improved, the temperature was normalized. Other reactions specific for tuberculosis were negative. During the control CT scan small positive dynamics was determined, since the mass dimensions slightly decreased. Due to the absence of a reaction specific for tuberculosis, it was recommended to conduct one more examination of the patient for the purpose of determining the causation of the disease. Due to low information value of the two previous needle biopsy procedures, a decision was taken to subject the patient to a manipulation with the use of the proposed method of minimally invasive surgical procedure.

[0187] Before conducting a needle biopsy, the patient's chest was studied with contrasting on the CT scanner 1. The above-said site actively accumulated the contrast preparation along the periphery from the cavity. The data was transmitted from the CT scanner 1 to the robotic apparatus computer system 4 for the purpose of mapping out the course of and modeling a needle biopsy procedure as well as for determining all parameters and conditions optimal for that needle biopsy procedure.

[0188] The data was transmitted to the automatic robotic apparatus (the robotic arm 6 with the computer system 4), which conducted the manipulation with the use of the hollow U-shaped biopsy head 14.

[0189] During the manipulation the CT scanner 1 continuously scanned the entire course of the procedure for exercising control over important advancements of the intratissular anesthesia needle 18 and the biopsy needle 19; anesthesia was given as well. In this way reliable data (images) on hitting the mass with the needle 19 was obtained, and a sample of a histological material was collected reliably and successfully from the site where the contrasting preparation was accumulated most actively.

[0190] The material sample was sent for a histological study.

[0191] Opinion: epidermoid carcinoma.

[0192] Diagnosis: an epidermoid carcinoma in the upper lobe of the left lung.

[0193] This Example shows that the proposed method of minimally invasive surgical procedure provides the possibility of conducting a needle biopsy of not only a mass itself, but also a selected mass site, and obtaining a reliable, most accurate result.

[0194] No damage of the patient's critical organs were identified; painful sensations were minimum, no infections were identified, the skin integrity was not violated, the procedure was conducted quickly and insensibly. The post-procedure recovery was quick and easy.

[0195] Thus, the proposed method may be most successfully used for conducting a minimally invasive surgical procedure, namely, a needle biopsy of the organs of the chest, the abdominal cavity, the small pelvis and the limbs.