Additive for Food, Drink and Pharmaceutical Products to Improve Health and Well-Being
20220347153 · 2022-11-03
Assignee
Inventors
Cpc classification
A61K9/2018
HUMAN NECESSITIES
A23L33/105
HUMAN NECESSITIES
A61K8/498
HUMAN NECESSITIES
A61K31/047
HUMAN NECESSITIES
A61K47/10
HUMAN NECESSITIES
A61K47/26
HUMAN NECESSITIES
A61K9/0095
HUMAN NECESSITIES
A61K9/0053
HUMAN NECESSITIES
A61K31/352
HUMAN NECESSITIES
A61K9/0056
HUMAN NECESSITIES
A61K9/0014
HUMAN NECESSITIES
International classification
A61K31/352
HUMAN NECESSITIES
A61K31/047
HUMAN NECESSITIES
A61K47/10
HUMAN NECESSITIES
Abstract
An additive for use alone as a tablet or capsule or with a base product to produce an enhanced product that provides health benefits to a person who consumes or uses the additive, including stimulating naturally occurring enzymes in the person's body. The additive has one or more hydrogenated substances, such as Erythitol, Xylitol, hydrogenated dihydromyricetin and/or Quercetin dihydrate, and the flavonoid Dihydromyricetin. The flavonoid may be extracted from a Vine Tea plant and/or a plant chosen from the genus Hovenia, such as the Japanese raisin tree. The additive may also have one or more of a solvent, such as a bicarbonate compound or an alcohol solvent, a pH balancing acid and/or a preservatives. The base product may be a liquid, solid, powder, chewable, pharmaceutical, cosmetic or a lotion or other applied product. The enhanced product are a base product that is enhanced by the additive.
Claims
1. An additive for improving the health and well-being of a product user, wherein said additive comprises: an effective amount of one or more hydrogenated substances added to or integral with said base product; and one or more flavonoids combined with said hydrogenated substance, said one or more flavonoids selected from a source of flavonoids to provide one or more health benefits for the product user who utilizes the enhanced product, said one or more flavonoids comprising Dihydromyricetin, wherein said additive is beneficially configured to be consumed by the product user alone, such as in the form of a tablet or capsule, or in combination with a base product in which said additive is added to the base product to form an enhanced product during production of the base product and/or added to the base product after production of the base product but before the product user eats, chews, swallows, drinks or applies the enhanced product.
2. The additive of claim 1, wherein said one or more hydrogenated substances are selected from the group comprising Erythitol, Xylitol, hydrogenated dihydromyricetin and Quercetin dihydrate.
3. The additive of claim 1, wherein said source of flavonoids is at least one of a Vine Tea plant and a Hovenia plant.
4. The additive of claim 1 further comprising a solvent.
5. The additive of claim 4, wherein said solvent comprises at least one of an alcohol solvent and a bicarbonate compound.
6. The additive of claim 1 further comprising a pH balancing acid.
7. The additive of claim 1 further comprising a preservative.
8. The additive of claim 1, wherein said base product is one of a liquid product, a solid product, a powder product and a chewable product.
9. The additive of claim 1, wherein said base product is a pharmaceutical product.
10. The additive of claim 1, wherein said base product is one of a cosmetic product and an applied product.
11. An additive to add to a base product to produce an enhanced product for improving the health and well-being of a product user of the enhanced product, wherein said additive comprises: an effective amount of one or more hydrogenated substances added to or integral with the base product, said hydrogenated substances comprising at least one of Erythitol, Xylitol, hydrogenated dihydromyricetin and Quercetin dihydrate, and one or more flavonoids combined with said base product and said hydrogenated substance, said one or more flavonoids selected from a source of flavonoids to provide one or more health benefits for the product user who utilizes the enhanced product, said one or more flavonoids comprising Dihydromyricetin and said source of flavonoids is at least one of a Vine Tea plant and a Hovenia plant, wherein said additive is beneficially configured to be added to the base product during production of the base product and/or added to the base product after production of the base product but before the product user eats, swallows, chews, drinks or applies the enhanced product.
12. The additive of claim 11 further comprising at least one of an alcohol solvent and a bicarbonate compound.
13. The additive of claim 1, wherein said enhanced product is one of a liquid product, a solid product, a powder product, a chewable product, a pharmaceutical product, a cosmetic product and an applied product.
14. An enhanced product to improve the health and well-being of a product user of the enhanced product, wherein said enhanced product comprises: one or more hydrogenated substances; and one or more flavonoids combined with said hydrogenated substance, said one or more flavonoids selected from a source of flavonoids to provide one or more health benefits for the product user who utilizes the enhanced product, said one or more flavonoids comprising Dihydromyricetin, wherein said enhanced product is configured to be consumed by the product user alone, such as in the form of a tablet or capsule, or in combination with a base product.
15. The enhanced product of claim 14, wherein said source of flavonoids is at least one of a Vine Tea plant and a Hovenia plant.
16. The enhanced product of claim 15, wherein said one or more hydrogenated substances are selected from the group comprising Erythitol, Xylitol, hydrogenated dihydromyricetin and Quercetin dihydrate.
17. The enhanced product of claim 14, wherein said one or more hydrogenated substances and said one or more flavonoids are added to the base product to form said enhanced product during production of the base product and/or added to the base product after production of the base product but before the product user eats, chews, swallows, drinks or applies the enhanced product.
18. The enhanced product of claim 17, wherein said source of flavonoids is at least one of a Vine Tea plant and a Hovenia plant and said one or more hydrogenated substances are selected from the group comprising Erythitol, Xylitol, hydrogenated dihydromyricetin and Quercetin dihydrate.
19. The enhanced product of claim 1 further comprising at least one of a pH balancing acid and a preservative.
20. The enhanced product of claim 14 further comprising a solvent, said solvent comprising at least one of an alcohol solvent and a bicarbonate compound.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0034] In the drawings which illustrate the preferred embodiments and the best modes presently contemplated for carrying out the present invention:
[0035]
[0036]
[0037]
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0038] With reference to the figures where like elements have been given like numerical designations to facilitate the reader's understanding of the present invention, the preferred embodiments of the present invention are set forth below. The enclosed figures are illustrative of several potential preferred embodiments and, therefore, are included to represent several different ways of configuring the present invention. Although specific components, materials, configurations and uses are illustrated, it should be understood that a number of variations to the components and to the configuration of those components described herein and shown in the accompanying figures can be made without changing the scope and function of the invention set forth herein. For instance, although the description and figures included herewith generally describe and show particular materials and configurations for the new additive, persons who are skilled in the art will readily appreciate that the present invention is not so limited. In addition, the exemplary embodiments of the present device are shown and described with only those components which are required to disclose the present invention. Many of the necessary steps or components for manufacturing or using the present invention are not shown in the drawings or necessarily described below, but which are well known to persons who are skilled in the relevant art. As will be readily appreciated by such persons, the various elements of the present invention that are described below may take on any form consistent with forms which are readily realized by one of ordinary skill in the art having knowledge of additives that can be utilized with foods, drinks, chewables, pharmaceuticals, cosmetics and the like to produce an enhanced product.
[0039] A new additive that is configured pursuant to one or more of the preferred embodiments of the present invention is shown generally as 50 in
[0040] The sweetener base 12 for the sweetener additive 10 comprises one or more sweeteners 22 that may be natural, artificial or combinations of natural and artificial components, as shown in
[0041] Confectioner's sugar, which is also referred to as powdered sugar, icing sugar and 10× sugar, is a highly refined cane sugar 24 that is made from beets or sugar canes that has been mechanically ground to produce a super fine, powdery sugar. Evaporated cane juice (also called dried cane juice, crystallized cane juice, cane crystals, cane juice crystals and milled cane sugar) is a refined cane sugar 24 made from sugar cane that retains some of the nutrients of the sugar cane. Evaporated cane juice is available in a variety of forms and under different names. This sweetener is slightly less processed than white sugar. Brown sugar is highly refined white sugar combined with varying amounts of molasses to yield golden, light, or dark brown sugar. Cane sugar 24 also includes fructose, glucose, sucrose and galactose, which are refined sugars which are made from sugar canes or sugar beets. Table sugar, which is refined white sugar, is made up of equal amounts of the simple sugars glucose and fructose, which are joined together by chemical bonds. Galactose is a refined sweetener that is found in a number of commercially prepared products. A galactose molecule linked with a glucose molecule forms a lactose molecule.
[0042] Another category of sweeteners 22 that are suitable for use as the sweetener base 12 for the sweetener additive 10 are collectively referred to herein as “other plant sugars” 26. One such other plant sugar 26 is referred to as beet sugar, which is a white sugar that is derived from beets. This sweetener is highly refined and has no nutrient value. Many people believe that beet sugar produces products with an inferior taste and texture compared to those made with cane sugar. Corn syrup is another type of other plant sugar 26. This thick, sweet syrup is made by heating corn starch with an acid or by combining it with enzymes to break it down. As such, corn sugar is a highly refined sweetener and has almost no nutritional value. Corn syrup solids, also called dried glucose syrup or glucose syrup solids, is corn syrup that has been concentrated to contain less than 10% water. Crystalline fructose is a sweetener produced by allowing the fructose from fructose-enriched corn syrup to crystallize. Agave is an other plant sugar 26 that is commercially produced from several species of the agave plant. Agave has more concentrated fructose than does high fructose corn syrup and has been shown to alter liver function, promote obesity, and increase insulin resistance for both diabetics and non-diabetics. Barley malt, which is also referred to as malt sweetener, is an other plant sugar 26 with a strong, distinctive flavor that is made from sprouted barley. Pure malt extract, which is relatively expensive, is often mixed with corn syrup, a less expensive product. Coconut sugar is produced from the sap of coconut flower buds (not the coconut itself). The sap is boiled to reduce moisture content and then dehydrated. There are concerns about the sustainability of producing coconut sugar due to the fact that coconut trees which are tapped for sap cannot produce coconuts. Date sugar, which is not really a refined sugar at all, is simply ground dates. This natural sweetener is high in fiber and nutrients and is considered to be a much better option than refined sweeteners. Date sugar can be used in place of sugar in some recipes. However, date sugar will not melt or dissolve in liquids as regular sugar does. Dextrose is a highly refined crystalline glucose that is made from starch. Dextrose produced from cornstarch may be listed as “corn sugar”, that produced from rice may read as “rice sugar”, and that made from wheat may be listed as “wheat sugar”.
[0043] Honey and juice concentrate are also other plant sugars 26. Honey, which is a sweetener made by bees from plant nectar, contains trace amounts of vitamins and minerals. The color and flavor of the honey depends on the source of the nectar (clover, buckwheat, orange blossom, etc.). Another type of syrup sugar 28 is juice concentrate, which is a sweetener that is made by concentrating fruit juice. Juice concentrate typically retains a small amount of nutrients and is preferable to many other types of sweeteners when sweetening fruit-based dishes. In one example, grape juice concentrate is combined with rice syrup to produce a sweetener. Maltodextrins is a family of highly-refined sweeteners that are made from rice, corn, or potato starch. Maltose, also called malt sugar, is a sweetener that is made from malted grains. Mannitol is a sugar alcohol that is, unfortunately, known to cause digestive problems in some people. Maple syrup is a concentrated natural sweetener that is made by boiling down sap from the sugar maple tree.
[0044] Another category of sweeteners 22 that are suitable for use as the sweetener base 12 for the sweetener additive 10 are collectively referred to herein as “syrup sugars” 28. One syrup sugar 28 is high-fructose corn syrup (HFCS), which is a syrup made from corn that has undergone enzymatic processing to convert some of its glucose into fructose. Molasses, also called treacle, is a thick, dark syrup that is a by-product of the production of beet sugar or cane sugar 24. Sorghum syrup, which is sometimes called molasses, is a different product produced in a different way. Sorghum syrup, commonly referred to as sorghum molasses is a syrup that is made by crushing the stalks of the sorghum plant and then cooking the resulting syrup to concentrate it. In general, sorghum syrup is a more healthful option than regular or blackstrap molasses, which is a type of molasses. Blackstrap molasses is a thick, viscous, dark-colored syrup with a bittersweet flavor that is a waste product from processing sugar cane or beet into table sugar. Brown rice syrup is a thick, syrupy sweetener which is made by cooking brown rice flour or brown rice starch with enzymes. Some people believe brown rice contributes to the development of candida (yeast) more than any other type of sweetener 22.
[0045] Another category of sweeteners 22 that are suitable for use as the sweetener base 12 for the sweetener additive 10 are collectively referred to herein as “artificial sugars” 30. One example of an artificial sugar 30 is acesulfame potassium (acesulfame-K), which is also called Sunett®, a registered trademark of the Celanese Corporation. This artificial sugar 30 is a potassium salt containing methylene chloride, a known carcinogen. Long term exposure to methylene chloride can cause headaches, nausea, emotional imbalances, and damage to the liver and kidneys. Another artificial sugar 30 is acesulfame, which has been shown to produce breast tumors, lung tumors, and other types of tumors, leukemia, and chronic respiratory disease in rodents. The artificial sugar 30 aspartame, which is known by a variety of brand names, is an artificial sweetener that is comprised of approximately 50% phenylalanine, 40% aspartic acid, and 10% methanol and which is approximately 200 times sweeter than sugar. Reported side effects from the use of aspartame include abdominal pain, anxiety, arthritis, depression, headaches, fibromyalgia, memory loss, nausea, heart palpitations, irritable bowel syndrome, seizures, neurological disorders, vision problems, and weight gain. This artificial sugar 30 has also been shown to damage bacteria in the gut.
[0046] Yet another category of sweeteners 22 that are suitable for use as the sweetener base 12 for the sweetener additive 10 are collectively referred to herein as “other sugars” 32, which include, but are not limited to lactose, Sorbitol and Xylitol. As well known, lactose is the sugar that is found naturally in dairy products. It is usually the main factor responsible for milk intolerance. Sorbitol and Xylitol are alcohol sugars that, unfortunately, can cause digestion problems for some people.
[0047] As set forth above and shown in
[0048] As set forth above, the new sweetener additive 10 also comprises a quantity of one or more flavonoids 14 that are selected from a source of flavonoids 15. As shown in
[0049] A wide variety of flavonoids can be extracted from the Hovenia plant 16 and utilized as the flavonoids 14 for the new sweetener additive 10. More specifically, as set forth above and shown in
[0050] As set forth in
[0051] People skilled in the art will readily appreciate that the flavonoids 14 set forth above are not the only flavonoids 14 that may be derived from the Hovenia plant 16 and that the health benefits 34 which are described above as being associated with those flavonoids 14 are not likely to be the only health benefits 34 that can benefit the consumer 18. More specifically, additional research into the Hovenia plant 16 is likely to result in the identification of additional flavonoids 14 that can be utilized with the sweetener additive 10 to provide one or more health benefits 34. Likewise, additional research and study into the above flavonoids 14, as well as any future identified flavonoids 14 from the source of flavonoid 14, including from the Hovenia plant 16, is likely to identify other health benefits 34 that can benefit the consumer 16 who consumes a consumable product 18 having or with the sweetener additive 10.
[0052] As set forth in U.S. patent application Ser. No. 16/998,933, which has the same inventor as the present patent application, the use of the flavonoid dihydromyricetin (DHM) in a chewing gum to reduce aldehyde accumulation in the body of the consumer 18, whether such accumulation is from the consumption of alcohol, or from pollution, smoking, vaping and/or poor eating habits and/or for consumers 18 whose body, for physiological or genetic reasons, do not naturally process aldehydes very well. The full and complete disclosure set forth in U.S. patent application Ser. No. 16/998,933 is hereby incorporated into the present text as though fully set forth herein.
[0053] As described above and shown on
[0054] The consumer 20 of the consumable product 18 having the sweetener additive 10 or to which the sweetener additive 10 is added can be any person who may benefit from the health benefits 34 resulting from combining one or more flavonoids 14 with the sweetener base 12. Although not yet fully studied, it is anticipated that the sweetener additive 10 may also be beneficial for certain animals, particularly dogs, cats and other pets, as the consumer 18 thereof.
[0055] In a second embodiment of the sweetener additive 10, which is shown in
[0056] In one embodiment, the aldehyde reducing component 42 of the new sweetener additive 10 comprises an aldehyde dehydrogenase enzyme. In another embodiment, the glucose reducing component 44 of the sweetener additive 10 comprises a glucose oxidase enzyme and/or a glucose dehydrogenase enzyme. In another embodiment, the alcohol reducing component 46 of the new sweetener additive 10 comprises an alcohol dehydrogenase enzyme and/or an alcohol oxidase enzyme. In yet another embodiment, the new sweetener additive 10 comprises combinations of two or more of the aldehyde reducing component 42, the glucose reducing component 44 and the alcohol reducing component 46 such that the sweetener additive 10 has at least one of the alcohol dehydrogenase enzyme, the glucose oxidase enzyme and the glucose dehydrogenase enzyme, and/or the aldehyde dehydrogenase enzyme and the alcohol oxidase enzyme. In any of these configurations, the sweetener additive 10 will be able to provide the health benefits 34 described above (from the flavonoids 14) and the additional health benefits 34 from further reducing the levels of aldehydes 38 and/or glucose 40 in the body of a consumer 20 who consumes a consumable product 18 having the new sweetener additive 10. The added enzymes 36 will supplement the naturally occurring enzymes in the body of the consumer 20 and the flavonoids will stimulate both the added enzymes 36 and the naturally occurring enzymes.
[0057] Utilizing the sweetener additive 10 with the addition of the aldehyde reducing component 42, glucose reducing component 44 and/or alcohol reducing component 46 with the flavonoids 14 will help safely and effectively remove aldehyde 38, glucose 40 and/or alcohol 41 from the bloodstream of a consumer when he or she consumes a consumable product 18 having the new sweetener additive 10. More specifically, once a consumer 20 consumes the consumable product 18, the digestive process of his or her body will result in the aldehyde reducing components 42, glucose removing components 44 and/or the alcohol reducing components 46 being absorbed into his or her bloodstream through the stomach and other internal organs. As well known in the art, the additive enzymes 36 will start working on the consumable product 18 in the stomach as soon as it is consumed and continue working on the glucose 40 and alcohol 41 components of the consumable product 18 as they work their way through the digestive process of the consumer 20, thereby converting the various glucose 40 and alcohol 41 (as ethanol) components before the small intestine directs these components into the bloodstream. With regard to the aldehyde reducing component 42, once absorbed into the person's bloodstream, the aldehyde reducing components 42 will react with the aldehyde 38 in the person's bloodstream to remove or at least lower the amount of aldehyde 38 in his or her body, including that added by the reduction of the glucose 40 and alcohol 41, thereby preventing or reducing the harmful effects of a buildup of aldehyde 38 in the consumer's body. Likewise, once absorbed into the person's bloodstream, the glucose reducing components 44 will react with glucose 40 in the person's bloodstream to remove or at least lower the amount of glucose 40 in his or her body, which will prevent or reduce the harmful effects of a buildup of glucose 40. The alcohol reducing component 46 will help convert the ethanol from the alcohol 41 to lessen the likelihood of the alcohol 41 entering the consumer's bloodstream.
[0058] As well known in the art, the build-up of aldehyde 38, often in the form of acetaldehyde, in a consumer's body can result from the consumption of alcohol. Not only is acetaldehyde a known carcinogen, its toxic effects are a well known cause of many of the side effects of consuming alcohol, particularly an alcohol hangover (as set forth in the Background). Removing acetaldehyde from the person's bloodstream is known to reduce hangover symptoms. When the ability of a person's body's to oxidize acetaldehyde to acetate is inhibited, typically either chemically or due to genetics for certain persons, amplified hangover symptoms are common. In addition to aldehyde 38 being introduced into a person's bloodstream by alcohol, aldehyde 34 is known to enter a person's bloodstream as a result of exposure to a number of chemicals that are or can be found in the environment, workplace and other locations where a person may frequent and due to smoking, vaping and/or poor eating habits. As set forth in more detail below, the new sweetener additive 10 is safe and effective at removing aldehydes 38, including but not limited to acetaldehyde, from a person's bloodstream, no matter how it may enter the consumer's bloodstream.
[0059] In the sweetener additive 10, acetaldehyde and other aldehydes 38 are removed from a person's bloodstream by the inclusion of the aldehyde dehydrogenase enzyme into the sweetener additive 10. More specifically, in one embodiment, the sweetener additive 10 comprises a therapeutically effective amount of the aldehyde dehydrogenase enzyme. For purposes of describing the sweetener additive 10, a therapeutically effective amount is that amount of aldehyde dehydrogenase which is necessary, desired or beneficial to interact with the aldehyde 38 in a person's bloodstream to lower the level of aldehyde 38, which may be in the bloodstream due to the consumption of food, beverages and/or alcohol 41 or from other sources (as set forth above), to a level which is safe and which provides the various benefits that are sought by use of the new sweetener additive 10, including as applicable prevention or reduction of hangover symptoms. As will be readily appreciated by persons who are skilled in the art, the aldehyde dehydrogenase enzyme can be incorporated into sweetener additive 10 in a variety of different manners, whether directly or as a part of compounds containing the enzyme.
[0060] Likewise, glucose 40 is removed from a person's bloodstream by the inclusion of the glucose oxidase enzyme and/or glucose dehydrogenase enzyme into the sweetener additive 10. More specifically, in one embodiment of the new sweetener additive 10, the sweetener additive 10 comprises a therapeutically effective amount of glucose oxidase. In another embodiment, the new sweetener additive 10 has a therapeutically effective amount of glucose dehydrogenase. In yet another embodiment, the new sweetener additive 10 has a therapeutically effective amount of both glucose oxidase and glucose dehydrogenase. For purposes of describing sweetener additive 10, a therapeutically effective amount is that amount of glucose oxidase and/or glucose dehydrogenase which is necessary, desired or beneficial to interact with glucose 40 in a person's bloodstream to lower the level of glucose 40 in his or her body. As will be readily appreciated by persons who are skilled in the art, the glucose oxidase and glucose dehydrogenase enzymes can be incorporated into sweetener additive 10 in a variety of different manners, whether directly or as part of compounds that contain these enzymes.
[0061] Likewise, alcohol 41 (as ethanol) is removed from the bloodstream of a consumer 20 by the inclusion of the alcohol dehydrogenase enzyme and/or the alcohol oxidase enzyme into the sweetener additive 10. More specifically, in one embodiment, the sweetener additive 10 comprises a therapeutically effective amount of the alcohol dehydrogenase enzyme. In another embodiment, the new sweetener additive 10 has a therapeutically effective amount of the alcohol oxidase enzyme glucose dehydrogenase. In other embodiments, the new sweetener additive 10 has a therapeutically effective amount of both and/or a therapeutically effective amount of alcohol dehydrogenase enzyme and the alcohol oxidase enzyme. For purposes of describing the new sweetener additive 10, a therapeutically effective amount is that amount of alcohol dehydrogenase and/or alcohol oxidase which is necessary, desired or beneficial to interact with alcohol 41 in a person's bloodstream to lower the level of alcohol 41 in his or her body. As will be readily appreciated by persons who are skilled in the art, the one or more alcohol dehydrogenase and/or alcohol oxidase enzymes can be incorporated into the new sweetener additive 10 in a variety of different manners, whether directly or as part of compounds that contain these enzymes.
[0062] As set forth above, the new sweetener additive 10 comprises the sweetener base 12 and one or more flavonoids 14 that are selected from a source of flavonoids 15, which may be a Hovenia plant 16. The flavonoids are selected from the group comprising at least one of Apigenin, Flavanones, Kaempferol, Quercetin, Rutin, Myricetin, Dihdrokaempferol, Dihydromyricetin, Ampelopsin, Epigallocatechin gallate and Taxifolin. The sweetener base 12 is made up of one or more sweeteners 22. The quantity and type of flavonoids 14 in the sweetener additive 10 are selected to achieve general or specific health benefit 34 objectives. The sweetener additive 10 is generally utilized in the same manner as the prior art sweeteners 22 would be utilized, namely the sweetener additive 10 is included in a consumable product 18 during the manufacturing or production thereof and/or added to a consumable product 18 prior to or before consuming the consumable product 18. In contrast to prior art sweeteners 22, the new sweetener additive 10 will provide health benefits 34 to the consumer 20 consuming the consumable product 18. Specifically, as set forth in more detail above, the flavonoids 14 included in the new sweetener additive 10 provide a wide variety of health benefits 34 depending on the types and amounts of flavonoids 14 in the sweetener additive 10, including stimulating the naturally occurring enzymes in the consumer's body that remove aldehyde 38, glucose 40 and/or alcohol 41. The addition of the added enzymes 36, namely, the aldehyde reducing components 42, the glucose reducing components 44 and/or the alcohol reducing components 46 to the flavonoids 14 in a sweetener additive 10 incorporated in or utilized with a consumable product 18 provide the additional health benefit 34 of further reducing aldehyde 38, glucose 40 and/or alcohol 41 in the consumer's body by supplementing the naturally occurring enzymes in his or her body to further improve the health of the consumer 20 who consumes the consumable product 18. The action of the added enzymes 36 will also be stimulated by the flavonoids 14.
[0063] As will be readily appreciated by persons who are skilled in the relevant art, the amount of flavonoids 14 and the amount of aldehyde reducing components 42, glucose reducing components 44 and/or alcohol reducing components 46 in the sweetener additive 10 can be adjusted to achieve one or more health related objectives that are to be achieved by consuming a consumable product 18 having the sweetener additive 10. For instance, such persons will readily understand that if a slower/lesser or faster/increased metabolization of aldehyde 38, glucose 40 and/or alcohol 41 is desired or necessary, then the concentrations of the aldehyde reducing components 42, glucose reducing components 44 and/or alcohol reducing components 46 in the sweetener additive 10 should be adjusted accordingly to determine the therapeutically effective amount that will provide the desired beneficial effect. When consumed, the new sweetener additive 10 will aid in improving the general health of a consumer 20 who consumes a consumable product 18 having the sweetener additive 10 and, if the aldehyde reducing components 42, glucose reducing components 44 and/or alcohol reducing components 46 are utilized in the sweetener additive 10, will supplement naturally occurring enzymes to further help those consumers 20 who have problems with the build-up of aldehydes 38 from eating food and/or drinking beverages, including alcohol 41, or who are exposed to aldehydes 38 as a result of pollution, smoking, vaping and/or poor eating habits and/or for persons whose body, for physiological or genetic reasons, do not naturally process aldehydes 38 very well and for persons for whom glucose 40 and/or alcohol 41 are a problem.
[0064] The new additive 50 of the present invention shares some of the same components and has many of the same attributes and benefits as the sweetener additive 10 described above. As set forth in more detail below and shown in
[0065] In its broadest form, the additive 50 of the present invention generally comprises one or more specially selected flavonoids 14 and one or more specially selected hydrogenated substances 58, with the source of flavonoids 15 preferably being a Hovenia plant 16 or a Vine Tea plant 17, as best shown in
[0066] The flavonoid 14 for the additive 50 of the present invention is, as with the sweetener additive 10, selected to provide one or more health benefits 34 for the product user 56. With regard to the preferred embodiments of the additive 50 of the present invention, the flavonoid 14 is Dihydromyricetin 14a, as shown in FIG. 3. As noted above, this flavonoid 14 may also be utilized with the sweetener additive 10. In a preferred means of manufacturing the new additive 50, the Dihydromyricetin 14a is obtained from a Hovenia plant 16 and/or a Vine Tea plant 17 (e.g., as the source of flavonoids 15).
[0067] For use as an additive 50 that accomplishes the various objectives and which provides the aspects of the present invention, the present inventor solved several problems with regard to use of Dihydromyricetin 14a. One such problem is that Dihydromyricetin 14a, on its own, has a solubility of approximately 0.2 mg per ml of fluid, which is very low. Because the solubility of Dihydromyricetin 14a is so low, it cannot be effectively utilized as a medicine or supplement, despite the well known benefits of this flavonoid 14 for people (as well as certain animals). Another issue with Dihydromyricetin 14a is that, on its own, it has a bioavailability of approximately four percent, meaning that only about four percent of consumed Dihydromyricetin 14a enters a person's bloodstream and stays long enough to be biologically effective for product user 56. Yet another issue with Dihydromyricetin 14a is that Dihydromyricetin 14a has poor stability due to light sensitivity and other shelf-life limitations. Mixing an effective amount of one or more solvents 60, such as a bicarbonate substance 60a or an alcohol solvent 60b, increases the solubility of Dihydromyricetin 14a from approximately 0.2 mg per ml of fluid to approximately 114 mg per ml of fluid. Mixing an effective amount of a hydrogenated substance 58, such as Erythritol 58a or like substances, greatly improves the bioavailability of Dihydromyricetin 14a. With regard to the shelf life problem, the present inventor has found that mixing Dihydromyricetin 14a with an effective amount of Erythritol 58a and/or other hydrogenated substances 58 extends the Dihydromyricetin 14a shelf-life due to the effects created by the bond that is formed between the two substances. The present inventor has also found that combining Dihydromyricetin 14a with an effective amount of a bicarbonate substance 60a (such as sodium bicarbonate) and Erythitol 58a is optimum for increasing the bioavailability of the Dihydromyricetin 14a and other flavonoids 14 having low solubility and relatively low bioavailability and for increasing the shelf life of Dihydromyricetin 14a and, as a result, the additive 50.
[0068] The mechanism for the above interactions is that Dihydromyricetin 14a is able to form a bond with sodium bicarbonate and/or other bicarbonates 60a in a manner which allows the Dihydromyricetin 14a to dissolve in water and other fluids. In addition, Dihydromyricetin 14a is able to bond with Erythitol 58a and other hydrogenated substances 58, which allows the Dihydromyricetin 14a to dissolve in water and other fluids. The present inventor has found that the combination of Dihydromyricetin 14a, sodium bicarbonate 60a and Erythitol 58a is currently the most effective bond to dissolve the Dihydromyricetin 14a in fluid while at the same time helping facilitate the Dihydromyricetin 14a entering the bloodstream of the product user 56 because the Erythitol 58a is not just able to improve solubility, it also improves permeability (by acting as a vascular dilator and by promoting endothelial health). As well known in the art, a combination of increased solubility and permeability directly relate to the bioavailability effectiveness of a substance, namely its ability to enter the user's bloodstream.
[0069] The present inventor has also found that Dihydromyricetin 14a is able to dissolve in greater amounts when it is combined with a solvent. In particular, mixing Dihydromyricetin 14a with a solvent, such as an alcohol solvent and/or a bicarbonate, which may be a bicarbonate powder or gas (e.g., sodium bicarbonate or the like). The present inventor has also found that when an alcohol solvent is added to the combination of the flavonoid Dihydromyricetin 14a and the hydrogenated substance Erythritol readily dissolves and improves solubility and permeability of the Dihydromyricetin 14a. These combinations vastly improve the ability of the product user 56 to obtain the otherwise difficult to obtain (i.e., relative to consuming the Dihydromyricetin 14a alone) benefits of Dihydromyricetin 14a.
[0070] The hydrogenated substances 58 that have been found to be useful for mixing with the flavonoid Dihydromyricetin 14a to obtain the new additive 50 of the present invention for producing the enhanced product 52 include Erythritol 58a, Xylitol 58b, hydrogenated Dihydromyricetin 58c and Quercetin dihydrate 58d, as set forth on
[0071] The base product 54 to which the new additive 50 is added or utilized with can include a wide variety of different liquid products 66, solid products 68, powdered products 70, chewable products 72, pharmaceutical products 74, cosmetic products 76 and applied products 78, as set forth on
[0072] Certain features with regard to the enhanced products 52 and base products 54 that have been determined to be relevant to the new additive 50 of the present invention include: (1) the addition of Erythritol 58a to Dihydromyricetin 14a greatly improves the ability of Dihydromyricetin 14a to dissolve in water; (2) a blend (at an approximate 1:4 ratio) of Dihydromyricetin 14a and Erythritol 58a dissolves more easily at room temperature than Dihydromyricetin 14a alone; (3) a blend (of an approximate 1:10 (or greater) ratio) of Dihydromyricetin 14a and Erythritol 58a dissolves more easily in water than a 1:4 ratio of these substances; (4) the new additive 50 can be used in a variety of different beverage formats, including water based, acidic carbonated, and alcoholic (up to approximately 40% alcohol by volume or ABV) beverages; (5) it is possible to prepare a stable beverage that contains a relatively high concentration of the additive 50 with gentle heating and low pH; (6) in general, low pH benefits the stability of the Dihydromyricetin 14a; and (7) the new additive 50, containing at least the Dihydromyricetin 14a and hydrogenated substances 58 is more stable in the low pH model recovery beverage than in plain water.
[0073] Several example compositions for the new additive 50 and, in certain examples, the incorporation of the additive 50 into a base product 54 to produce an enhanced product 52 are set forth below:
Example #1—Recovery Powder (Powder Product 70)
[0074] Mix 259 mg Dihydromyricetin 14a with 6.22 g of Erythritol 58a (the hydrogenated substance 58), approximately a 1:24 ratio, with 207 g of Sodium Bicarbonate 60a (as the solvent 60) to produce the new additive 50. Add the new additive 50 in powder form (preferably with 155 mg Monk Fruit BS and 155 mg Stevia to sweeten the additive 50) to a 12 oz glass or bottle of water (as the base product 54) to produce an enhanced water (as the enhanced product 52).
Example #2—Recovery Powder (Powder Product 70)
[0075] Mix 259 mg Dihydromyricetin 14a with 6.42 g of Erythritol 58a (the hydrogenated substance 58), approximately a 1:24 ratio, to produce the new additive 50. Add the new additive 50 in powder form (preferably with 155 mg Monk Fruit BS and 155 mg Stevia to sweeten the additive 50) to a 12 oz cup of hot coffee or tea (as the base products 54) to produce an enhanced coffee or tea (as the enhanced product 52).
Example #3—Alcohol/Spirits Recovery (Liquid Product 66)
[0076] Mix 450 mg of Dihydromyricetin 14a with 4.5 g of Erythritol 58a (the hydrogenated substance 58), a 1:10 ratio, to produce the new additive 50. Add the new additive 50 to a 750 mL bottle of 80 proof alcohol, such as vodka or the like (as the base product 54) to produce an enhanced bottle of alcohol (as the enhanced product 52). The 4.95 g of the new additive 50 (per 750 ml bottle of 80 proof spirits) can be added by the manufacturer prior to bottling the alcohol and/or by the consumer after opening the bottle (e.g., a consumer product additive). The general rule for alcohol is 16.5 mg of additive 50 per 1 mL of actual alcohol, whether in the form of beer, wine, alcoholic carbonated drinks, spirits or the like. For instance, 750 mL vodka at 40% alcohol content (80 proof) has 300 mL of alcohol that requires 4.95 g of the new additive 50, 750 mL wine at 12% alcohol content has 90 mL of alcohol that requires 1.485 g of the new additive 50, and 340 ml of beer at 6% alcohol content has 20.4 mL of alcohol that requires 336 mg of the new additive 50.
Example #4—Beverage as a Health Drink or Alcohol Mixer (Liquid Product 66)
[0077] Mix 50 mg of Dihydromyricetin 14a with 500 mg of Erythritol 58a (the hydrogenated substance 58) to produce the new additive 50. Add the 550 mg of the new additive 50 to a can or bottle (whether 8, 12, 16 or 24 oz) of soda, water, energy drink or the like by the manufacturer prior to bottling the drink and/or by the consumer after opening the bottle to produced an enhanced beverage (as enhanced product 52).
Example #5—Beverage as a Recovery Drink (Liquid Product 66)
[0078] Mix 300 mg of Dihydromyricetin 14a with 3 g of Erythritol 58a (the hydrogenated substance 58) to produce the new additive 50. Add the 3.3 g of the new additive 50 to a can or bottle (whether 8, 12, 16 or 24 oz) of soda, water, energy drink or the like by the manufacturer prior to bottling the drink and/or by the consumer after opening the bottle to produce an enhanced recovery drink (as the enhanced product 52).
Example #6—Capsule or Tablet (Pharmaceutical Product 74)
[0079] Mix 100 mg of Dihydromyricetin 14a with 600 mg of Erythritol 58a (the hydrogenated substance 58) and 100 mg of Sodium Bicarbonate 60a (as the solvent 60) to produce the new additive 50. Add the new additive 50 to an 800 mg capsule or compress the new additive into an 800 mg tablet (as the enhanced product 52).
Example #7—Shampoo (Cosmetic Product 76)
[0080] Mix 5 g of Dihydromyricetin 14a with 50 g Erythritol 58a (the hydrogenated substance 58) to produce the new additive 50. Add 55 g of the new additive 50 per bottle of shampoo (as the base product 54) by the manufacturer prior to bottling and/or by the consumer after opening the bottle to produced an enhanced shampoo (as the enhanced product 52).
Example #8—Lotion (Applied Product 78)
[0081] Mix 2.5 g of Dihydromyricetin 14a with 25 g of Erythritol 58a (the hydrogenated substance 58) to produce the new additive 50. Add 27.5 g of the new additive 50 per bottle of lotion (as the base product 54) by the manufacturer prior to bottling and/or by the consumer after opening the bottle to produced an enhanced lotion (as the enhanced product 52).
Example #9—Sweetener (Powder Product 70)
[0082] Mix one part Dihydromyricetin 14a with 50 parts Erythritol 58a (the hydrogenated substance 58) with 0.75 parts Sodium Bicarbonate 60a (as the solvent 60) to produce the new additive 50. Add the new additive 50 to Monk Fruit and/or Stevia Leaf Extract (as the base products 54) as desired for flavor and sweetness to produce an enhanced sweetener (enhanced product 52).
Example #10—Sweetener (Powder Product 70)
[0083] Mix one part 20:1 Raisin Tree Extract (as the source of Dihydromyricetin 14a) with five parts of Erythritol 58a (the hydrogenated substance 58) to produce the new additive 50. Add the new additive 50 to Monk Fruit and/or Stevia Leaf Extract (as the base products 54) as desired for flavor and sweetness to produce an enhanced sweetener (enhanced product 52).
Example #11—Sweetener (Powder Product 70)
[0084] Mix one part 10:1 Raisin Tree Extract (as the source of Dihydromyricetin 14a) with five parts of Erythritol 58a (the hydrogenated substance 58) to produce the new additive 50. Add the new additive 50 to Monk Fruit and/or Stevia Leaf Extract (as the base products 54) as desired for flavor and sweetness to produce an enhanced sweetener (as the enhanced product 52).
[0085] As set forth above and shown in the examples, the new additive 50 of the present invention can be utilized with a wide variety of liquid products 66, solid products 68, powdered products 70, chewable products 72, pharmaceutical products 74, cosmetic products 76 and applied products 78. As also set forth above, the new additive 50 can be utilized by itself in a capsule or tablet form that can be, as may be desired, swallowed with a glass of water or other liquid, be dissolved in the liquid prior to drinking (such as with antacids and the like) and/or chewed (as a chewable product 72). The liquid products 66 can be water, juice, sports drinks, protein drinks, carbonated drinks, spirits, beer, alcoholic mixed drinks, wine, coffee, tea and the like. The solid products 68 can be food, candy, chocolate, energy bars, protein bars and the like. The powder products 70 can be provided in a form that is accessible to the consumer, such as in containers in which the desired amount is removed (i.e., similar to powdered chocolate and the like) or in small, individual packets (i.e., similar to packets of sugar or the like). The powder formulas can be combined with almost anything because, being a powder, they are soluble and highly bioavailable. Typically, however, the more acidic a base product is the more bicarbonate may be needed to change the pH balance. The chewable products 72 can be just the additive 50 and be of the type that allows a person to easily chew the tablet or solid capsule and, if desired, can be mixed with sweeteners or other flavorings or the additive 50 can be mixed with a base product 54 such as gum or other chewable. The pharmaceutical product 74 can comprise just the additive 50 or, if desired, the additive 50 can be mixed with medicines, vitamins or other pharmaceutical or pharmaceutical-type products. The cosmetic product 76 can be products such as shampoo, conditioner, lipstick, facial powder or the like. The applied product 78 can be any type of product that is placed on the body of a person or animal, such as moisturizing lotions, sun screens, sun burn lotions (such as those having aloe and the like), cleaning lotions, healing lotions, salves and the like. As will be readily appreciated by persons who are skilled in the relevant art, the above examples are provided only for exemplary purposes and are not intended to limit the scope of the new additive 50 of the present invention in any manner. As such, persons who are skilled in the relevant art will readily appreciate that the new additive can be utilized with many other products, including products that are not in one of the categories set forth above.
[0086] In the preferred configurations, the new additive 50 comprises all-natural ingredients that produce a unique nutraceutical delivery method with exceptional solubility and bioavailability. The additive 50 provides optimal application, utilization, and concentration of dihydromyricetin 14a, which usually has very low solubility and permeability to allow a person to more easily use or consume the additive and obtain the benefits of the dihydromyricetin 14a. More specifically, as set forth above, the new additive 30 increases the solubility and permeability of dihydromyricetin 14a exponentially up from 0.2 mg to a maximum of 114 mg* per mL (a 570 times increase). Additionally, the additive 50 contains an all natural vasodilator which opens up the cells throughout the digestive track for accelerated absorption into the bloodstream and near complete absorption when it reaches the small intestine. As soon as the additive 50 enters a persons mouth, it begins to be absorbed, the effects are immediate and highly effective in small doses. In addition, the new additive 50 require far less quantity to be effective than other additives that attempt to achieve some of the benefits that are obtained by using the new additive 50. The Dihydromyricetin 14a (DHM or DMY) is a highly researched and studied flavonoid commonly used for health supplements. The original source of Dihydromyricetin 14a, the Japanese Raisin Tree has been used for over a thousand years as a recovery from a hangover. Pure Dihydromyricetin 14a comes from Vine Tea Extract, while the original source of Dihydromyricetin 14a, namely Raisin Tree Extract, is most commonly used for food and beverages.
[0087] The Dihydromyricetin 14a provided by the new additive 50 may be able to be utilized for (based on studies) alcohol intoxication, anxiety, diabetes, liver health, Alzheimer's, dementia, aging, neurological disorders and traumatic brain injury, among others. As set forth above, Dihydromyricetin 14a catalyzes the enzymes alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which process ethanol and its toxic byproduct acetaldehyde. The dihydromyricetin mitochondrial biogenesis process maintains bioenergetics, reduces oxidate stress and activates lipid oxidation pathways. Dihydromyricetin 14a also catalyzes glucose dehydrogenase (GDH). When a sugar enters the body the liver requires these enzymes to break down those sugars. However, when the body encounters an over abundance of sugar in the form of ethanol and/or glucose it struggles to completely convert them into what essentially becomes vinegar (acetate) and water. Instead the human body tends to convert sugars into acetaldehyde “in the hope” the body will be able to process the toxins later. Adding Dihydromyricetin 14a enables the human body to process sugars in a way that actively converts them quickly, while also eliminating the need to store acetaldehyde. The new additive 50 contains Dihydromyricetin 14a in a highly effective dose so a person that consumes the additive 50 will not experience the short and long term detrimental health effects of acquired and stored acetaldehyde. In addition, Dihydromyricetin 14a helps regulate GABA, which regulation is central to maintaining a healthy emotional state of mind. An imbalance in GABA causes stress and anxiety which can lead to additional health problems.
[0088] While there are shown and described herein specific forms of the invention, it will be readily apparent to those skilled in the art that the invention is not so limited, but is susceptible to various modifications and rearrangements in design and materials without departing from the spirit and scope of the invention. For instance, there may be numerous components of the embodiments described herein that can be readily replaced with equivalent functioning components to accomplish the objectives and obtain the desired aspects of the present invention. The various embodiments set forth herein are intended to explain the best mode of making and using the present invention as currently known to and appreciated by the present inventor and to enable other persons who are skilled in the relevant art to make and utilize the present invention. Although, the described embodiments may comprise different features, not all of these features are required in each and every embodiment of the present invention. More specifically, as will be readily appreciated by persons who are skilled in the art, certain embodiments of the present invention only utilize some of the features and/or combinations of features disclosed herein.